MDP0000203108, MDP0000203108 (mRNA) Malus spp. (apple)

Query:   28 KGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFE-QMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLV----SKDHEYDISINAPKLENL-----------------------DIKQDCLS---------------IY----LFENFKYLECCPPAFDQL---------------TQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXNDELY---------KELMLERGSRTCWV 1185
            + +D IS LPD +LCHILSF+PTK++V TSILS RW+ ++ SVP LDF+ E  ++ +   E     + F  FVD VL   +   I+KFRL    R  +   +  WIC A+   V ELDL +  D       ELP   F+CKTLVV+K+ S  +   +PT+   PSLK L +K VEY +DDS++KL S CPVLE+L I    RD   ++  VS P LK LR+ F +         +D +Y + ++AP LE L                       D++QD                  IY       N K L       D L               T+L+ +    + WD L   L  SPNLE+ VIE     E + +   W     VP CL+ HLK I IR   G  +  +  +YLLKN +VL +MT+   E Y         K L L RGSR+C+V
Sbjct:    7 ESRDIISNLPDELLCHILSFLPTKFAVGTSILSKRWRYLWASVPILDFDDELWLNPSTLVELEERIIMFQNFVDGVLRHSEVSCIKKFRLG--YRDNNLDSVYSWICIALERRVQELDLHLLID----WRVELPPMFFICKTLVVVKL-SCALFLDIPTTVWLPSLKALHLKSVEYSDDDSIQKLLSGCPVLEELVIEREERDNQWVV-NVSNPSLKILRIFFFTDGFAHPYEQEDQDYKVVVDAPNLEYLSITDYLSKDYFVKDLPSLVKAFIDVEQDSEEFEESPHNGGISYHGPIYELLGRISNVKCLSLTGVTLDSLSGTIGDYKLPTFHNMTRLEFLFIGGFNWDFLPNFLHSSPNLEALVIETGYTNELIPE--GWLMPLQVPACLVLHLKEIEIRRIVGEDYELEAVEYLLKNAEVLQQMTIDCHESYMDQEFCVCKKLLGLPRGSRSCFV 454          

Query:   16 NSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNY-VGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFK-----YLECCP-----------------------------------------------PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            ++  K +DRIS LPDAVLCHI+SF+PTK++V TS+LS RW+ ++ S+PNLDF+ + +    K    S   + F  FVD+VL       I+KFRL C     D S +  WICTA+  NV ELDL   ++  +    ELP   F CKTLVVLK+                                       CPVLE+L I     D    +F VSAP LK L + F          +Y + ++AP LE L I       YL  N       Y+   P                                               PAF  +T+L+L +   Y  + L + L  SPNLE  ++EN   +EC  +  +W     VP C+  HL  + I+ F G  +     ++LLKN +VL KM++
Sbjct:    3 STYGKSRDRISNLPDAVLCHIISFLPTKFAVGTSVLSKRWRYLWASIPNLDFDDDLLLDRDKPIGDSERSICFKNFVDKVLLHGSISCIRKFRLKCSDHELD-SAVNSWICTALERNVQELDLYFDTEYPI----ELPPKFFFCKTLVVLKL---------------------------------------CPVLEELVIERWRLDEQ-WVFNVSAPTLKSLAIYF---------SKYKLVVDAPNLEYLSITDFVSEDYLMSNLSSLVKAYVNVGPTIRGIDDQILYRGRIYELLRGISNVKHLSLSGETLHSLSGMFCGYELPAFHSVTRLELEVDYGYGLEFLKEFLDTSPNLEILILENVNKDEC--EIEEWTLPLQVPTCVELHLNEVEIKKFDGLDYELGAIEFLLKNARVLKKMSI 369          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSR---IVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISI-------------------NAPKLENLDIKQDCLSIYL------FENFKYLECCPP-------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVK--DYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMT---------VXNDELYKELML-ERGSRTC 1179
            D +S LPD +L  ILS +PTK  V TSILS RWK ++ S+P L+F     S    +           FV++ L L  +  IQ F L  Y   E   +   I  W+  A+  ++ ELD+   SDN       +P  +F CK+LVVLK++   +   +P++ C PSLK L ++ V Y +    E L S CPVLEDL +     D  +  F ++ P L++L +    +Y  S    Y+I                     N PKLE   +  D +S  +        + K+L  C          FDQL  LKL +      ++L Q LK SPNL   VI   +    +K  + G W    SVP CL+S L+ +   G+ G P  + +A Y+L+N + L   T         V N E+ KEL L  R S TC
Sbjct:    2 DNLSRLPDELLVRILSLVPTKVVVSTSILSKRWKFLWMSLPKLEFVDRDESLLVLKN----------FVNKNLPLHRAPVIQSFLLSLYESREKNIKPEDIRQWVEIAVSRHLRELDVSYSSDN---KENMVPNSLFACKSLVVLKLRFLTLM-DVPSTACLPSLKTLLLELVVYEDQKPFEALLSICPVLEDLEVWFR-EDESIQEFTINVPSLRKLCLHV--SYYWSSLERYEIDTPCLEYLELADWNDSPCLVKNMPKLEKAHV--DVVSFAVKNVIGSVASVKHLTVCSEDVYGDGIVFDQLEHLKLCICKDDSSNVLAQFLKDSPNLRVLVISQLDLHADLKTNEMGYWNQPSSVPECLLSSLQILNWEGYFGRPQDRDIAVYILRNARHLRTATIWGNTVEHDVPNLEMIKELTLSSRASSTC 411          

Query:   28 KGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQ-MSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLV----SKDHEYDISINAPKLENL-----------------------DIKQDCLS---------------IY-LFENFKYLEC-------------CP---PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIE 942
            + +D IS LPD +LCHILSF+PTK++V TSILS RW+ ++ SVP LDF+ E  ++ +   E     + F  FVD VL   +   I+KFRL                    R N           N+     ELP   F+CKTLVV+K+ S  +   +PT+   PSLK L +K VEY +DDS++KL S CPVLE+L I    RD   ++  VS P LK LR+ F +         +D +Y + ++AP LE L                       D++QD                  IY L      ++C             CP   P F  +T L+ +    + WD L   L  SPNLE+ VIE
Sbjct:    7 ESRDIISNLPDELLCHILSFLPTKFAVGTSILSKRWRYLWASVPILDFDDELWLNPSTLVELEERIIMFQNFVDGVLRHSEVSCIKKFRL------------------GYRDN-----------NLDNWGVELPPMFFICKTLVVVKL-SCALFLDIPTTVWLPSLKALHLKSVEYSDDDSIQKLLSGCPVLEELVIEREERDNQWVV-NVSNPSLKILRIFFFTDGFAHPYEQEDQDYKVVVDAPNLEYLSITDYLSKDYFVKDLPSLVKAFIDVEQDSEEFEESPHNGGISYHGPIYELLGRISNVKCLSLTGVTLDVSFLCPPILPTFHNMTCLEFLFIGGFNWDFLPNFLHSSPNLEALVIE 341          

Query:   22 QAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLS-LRDSLDIQKFRLHCYXRXEDFS----RIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNC-ITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLE--DLSINATVRDLLVLMFKVSAPELKRLRMTF---VSAYLVSKDHEYDISINAPKLENLDIKQ----DCLSIYLFENF--KYLECCPPA-------------------------------------------FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXNDEL 1140
            + + +DRIS LPD VL HILSF+PTK SV T+ LS+RW+ ++  +  L F  +  S  + ++    +  F + V+ VL+ LR+   IQK  L C     D       +  W+  AI  ++ EL+L ++ D      F+LPQ +F C  LV L +     ++    T+   PSLK L + + Y E  S+  L   C  +E  DL  +A   D + +      P LKRL++T    V AYL          +NAP L+ L+I Q    +  S+Y   N    YL+  P +                                           F  L +L+LVL   +  + L  L++K P L+  +I+N ++   +     W    S+P CL+SHL  I  +GF G+P      +Y+L+NG VL  + + +  L
Sbjct:   14 EEENEDRISYLPDGVLNHILSFLPTKTSVSTARLSSRWRHLWQHLSVLHFSDD--SHEYVDQPAERFKSFALLVNGVLALLRNPRAIQKMSLSCVHSFTDDKFREYSVETWVRAAIGPHLHELELTLFCDE-DAPDFKLPQALFSCPNLVSLSLSGAVHVSIQHSTAVSLPSLKMLMIDIGYVEVSSVNALLDGCSSIEILDLGFSAQSLDKVCV-----PPSLKRLKITIENDVGAYL---------EVNAPDLQYLNITQITFGEGFSLYSLPNVVEAYLDVFPTSLGSIVPLHNLFGALSGAKHLMLSRSTTKVKWLLGEPHEMLFQEFQYLIRLELVL-SWFNSNSLLHLIQKCPLLQPLIIQNDKERSPIL---AWSPQPSIPNCLVSHLSFIEFKGFRGFPDEVSFVEYVLQNGHVLKTLIIADISL 425          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQ-KFRLHCYXRXEDFSRIVGWICTAIRHNVV---ELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDL-----------SINATVRDLLVLMFKVS-----------APELKRLRMTFVSAYLVSKDHE--------YDISINAPKLENLDIKQDCLSIYLFENF----KYLECC------------PPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPN---LESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXG-YPHVKKVAKYLLKNGKVLTKMTV---------XNDELYKELMLE-RGSRTCWV 1185
            D+ S+LPD +L  +LSF+PTK +VRTS+LS RWKS++  +P L+++F   S + + + ++ ++   +   +  ++ +SL ++ ++      + ED   I  W+  A+  + V    L LC +++       +LP+ ++ CK++V+LK+K   I   +P   C PSLK L + +V Y ++DS+ +L S CPVLEDL            ++  V+ L  L  K+S            P LK L++T       S +          YD   + PKLE  D      +I  F  F    K L  C               F+QL QLK+   D     LL++LL+ SPN   LE+ VIE+  D               VP CL+S L+T       G   +   VAKY+L+N + L   T+           DE+ +EL L  +G  TC V
Sbjct:    2 DKTSQLPDELLVKVLSFLPTKDAVRTSLLSMRWKSLWMWLPKLEYDFRHYSVS-EGQGLARFITLSLLGHKAPAI-ESLSLKLRYGAIGSIKPED---IYLWVSLAVHDSNVRELSLKLCTFAER----PTKLPKSLYKCKSIVILKLKDE-ILVDVPRKVCLPSLKTLFLGRVTYSDEDSLHRLLSNCPVLEDLVVERDRIDNLGKLSVVVKSLQRLTLKMSCPCHLDGIMMNTPSLKYLKVTDERQESDSDNESDSDSPRYFYDFE-DMPKLEEADFVLTFQNIKKFFKFVTSIKRLSLCLGVYTEESLYHEGLVFNQLEQLKICSCDSDWSILLSRLLESSPNLRELEAYVIEDHPDRRVDLPNQWGNQLNCVPKCLLSSLETFKWSEMYGLLQNQMDVAKYILRNARCLKSATIFFPTTYAKETRDEMIEELSLSFQGPETCQV 438          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCY---XRXEDFSRIVGWICTAIRHNVVELDLCVYS--DNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDLSINA----TVRDLLVLM------------------FKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCL----SIYLFENFKYLECCPP-------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYG----KWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND---------ELYKELMLERGSRTC 1179
            D+I+ LPD +L  ILS++PT  +V TSILS RW+ ++  +PNLD+     ++ W  +     VG   F+ + L L  +  I+  R H      + ED  R   WI  A+  +V +LD+  +S  +NI   +F      F CK+LV LK++S  +   +P+  C PSLK L +  V + E  S+++L S CPVLEDLS+        ++L +++                  + +  P L+ L++   +    S DH   +  N PKL    +   C      I    + K+L  C          F+QL  L L +       LL QLLK SPNL   ++E    E+ V D G     W    SVP CL+S L+      + G P  + +A Y+LKN + L K T+  D          + KEL+    +R C
Sbjct:    2 DKINGLPDDLLVKILSYVPTDIAVSTSILSKRWEFLWMWLPNLDY-----TSRWCRK--PGDVGLRDFIHKNLPLHRAPVIESLRFHSNSPDIKPEDIRR---WIEIAVSRHVHDLDIDHFSENENIFLSSF------FACKSLVTLKLRSVTLR-DIPSMVCLPSLKTLLLDNVSFVEGKSLQELLSICPVLEDLSVYCDDYENTKELTIVVPSLLSLSLYIPDEWLLDGYWIDTPSLEYLKLEDWN----SCDH-LSLIKNMPKLREAYVDAKCFLPKSVIESITSVKHLTICSKDGYGDGFVFNQLEHLTLCVCRGDSPSLLGQLLKDSPNLR--ILEISVMEDHVDDVGISLDGWNQPSSVPECLLSSLQIFKWPQYLGRPEDRDIAVYILKNARHLKKTTILADRCERFVTQRRMIKELLQALPARIC 410          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRL---HCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-------------TFVSAYLVSK-DHEYDISI-NAPKLEN-------LDIKQDCLSIYLFENFKYLECCPPA-------FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND-------ELYKELML-ERGSRTC 1179
            DRIS LPD VL  ILSF+PTK +V TSILS RW+ ++  +  L F  ++ S        S +     F+DR L L  +  I+ FRL     + + ED   I  W+  A+   + EL   +YS +       LP  ++ CK+LV+LK+    +   +P   C PSLK L++K V Y +  S+++L   CPVLEDL +N +  D +  +  V  P L+RL +             + +S  LV + D+ +   I N PKL          DIK    SI    + K L             F+ L +  L L++ Y  +LL   LK SPNL   ++ ++ D+        W     VP C++S L+  T   + G P  + +A Y+LKN   L   T+ +D       E+  EL L  + S TC
Sbjct:    2 DRISGLPDEVLVKILSFVPTKVAVSTSILSKRWEFLWMWLTKLKFGSKRYSE-------SEFKRLQCFLDRNLPLHRAPVIESFRLVLSDSHFKPED---IRMWVVVAVSRYIRELK--IYSSHYGEKQNILPSSLYTCKSLVILKLDGG-VLLDVPRMVCLPSLKTLELKGVRYFKQGSLQRLLCNCPVLEDLVVNLSHHDNMGKL-TVIVPSLQRLSLSTPSSREFVIDTPSLLSFQLVDRNDNSHTFLIENMPKLREAYINVPFADIKSLIGSI---TSVKRLAISSEVGYGEGFIFNHLEE--LTLWNKYSSNLLVWFLKNSPNLRELMLVSETDDHENLGMLSWNQPSIVPECMLSSLQKFTWFKYLGRPQDRDIAVYILKNACRLRTATIKSDTRLFTKLEMITELRLSSQASSTC 404          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV--KVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLS--IYLFENFKYLECCP-----------------PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            DRIS LPD +L  ILS +PTK +V T ILS RW+ ++ +V  LDF+ E   ++ +  +     GF  FV  VL L D+  I++FRL C         I  W+C   R     ++L +     V     LP+C+F C T+ V+K+    +      S   P LK L V  +V +   D + KL + CP LEDL + +T  D                            + + D+   +        K+ CL   + +F     + C                   P FD+L QL+ + +  Y WDLL  LL++S  LE   I  +  +       +W     VP CL+ HLKT  +R + G         Y+++N +VL  MT+
Sbjct:   20 DRISHLPDVLLLQILSLLPTKQAVITGILSKRWRPLWPAVSVLDFDDE---SSPEFHHPGGLTGFAEFVYSVLLLHDAPAIERFRLRCANPNYSARDIATWLCHVARRRAERVELSLSLSRYVA----LPRCLFHCDTVSVMKLNGVFLNALASFSVSLPLLKVLHVGDRVLFGCHDYVVKLLAGCPALEDLVLESTYND------------------ACGGVVCAEGNFQLDLKHLSSAKIGFSWKERCLKSMLLIFRALSNVRCLSLSTSTVACLKHASTSDIPVFDKLIQLE-ISFGNYSWDLLASLLQRSHKLEVLTIYKEPQKYAKGQEPRWIHPLLVPECLL-HLKTFCLREYQGLETELDFVGYIMQNARVLETMTI 376          

Query:   31 GKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVS-APELKRLRMT-----------FVSA----YLVSKDHEYD-ISINAPKL------ENLDIKQDCLSIYLFENFKYLECCPP---------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDY------GKWRTTESVPICLISHLKTITIRGF-XGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            GKDRISELPDA+L  ILSF+PTK  V TS+ S +W+ ++  VPNL+F+ E      KE+Y  + +    F+     + +S     FRL       D   I  W+  A   ++ EL L V +D      F+ P  +  C TL  L++    I   + +     SL+ L ++ V Y ++ S+  L S CP+LE+L +     D  + +F +   P LKRL +             ++A    YL+ +D       +NAP+L      +   I  D    YL    + L    P          F QL  L++   +   WDLLT +L+ SP L+      K  + CVK +      GKW   + VP CL+SHL+T   R F  G    K++A Y+LKN + L K T   + +  E
Sbjct:    2 GKDRISELPDALLIKILSFLPTKIVVATSVFSKQWRPLWKLVPNLEFDSEDYDD--KEQYTFSEIVCKSFLSHKAPVLES-----FRLEFESEKVDPVDIGLWVGIAFSRHLRELVL-VAADTGTGTAFKFPSSLCTCNTLETLRLVL-LILVDISSPVVMKSLRTLHLELVSYKDESSIRNLLSGCPILEELLV-IRGEDSDIEVFTIDEVPSLKRLTINDDHDGQEFWGYVINAPSLKYLLIEDLRCPGFCLNAPELMEANIFDGTSITNDNFLGYLTSVKRLLLNLSPWKITYPTGSIFYQLVSLEMYTREIDWWDLLTLMLEHSPKLQVL----KLTDNCVKFHKNGLPGGKWNEPKYVPECLLSHLETFVWRRFDWGREEEKEIATYILKNARRLNKATFSTNPVNSE 400          

Query:   16 NSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNY-VGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFK-----YLECCP-----------------------------------------------PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            ++  K +DRIS LPDAVLCHI+SF+PTK++V TS+LS RW+ ++ S+PNLDF+ + +    K    S   + F  FVD+VL       I+KFRL C     D S +  WICTA+  NV ELDL   ++  +    ELP   F CKTLVVLK+                                       CPVLE+L I     D    +F VSAP LK L + F          +Y + ++AP LE L I       YL  N       Y+   P                                               PAF  +T+L+L +   Y  + L + L  SPNLE  ++EN   +EC  +  +W     VP C+  HL  + I+ F G  +     ++LLKN +VL KM++
Sbjct:    3 STYGKSRDRISNLPDAVLCHIISFLPTKFAVGTSVLSKRWRYLWASIPNLDFDDDLLLDRDKPIGDSERSICFKNFVDKVLLHGSISCIRKFRLKCSDHELD-SAVNSWICTALERNVQELDLYFDTEYPI----ELPPKFFFCKTLVVLKL---------------------------------------CPVLEELVIERWRLDEQ-WVFNVSAPTLKSLAIYF---------SKYKLVVDAPNLEYLSITDFVSEDYLMSNLSSLVKAYVNVGPTIRGIDDQILYRGRIYELLRGISNVKHLSLSGETLHSLSGMFCGYELPAFHSVTRLELEVDYGYGLEFLKEFLDTSPNLEILILENVNKDEC--EIEEWTLPLQVPTCVELHLNEVEIKKFDGLDYELGAIEFLLKNARVLKKMSI 369          

Query:   28 KGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQ-MSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLV----SKDHEYDISINAPKLENL-----------------------DIKQDCLS---------------IY-LFENFKYLEC-------------CP---PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIE 942
            + +D IS LPD +LCHILSF+PTK++V TSILS RW+ ++ SVP LDF+ E  ++ +   E     + F  FVD VL   +   I+KFRL                    R N           N+     ELP   F+CKTLVV+K+ S  +   +PT+   PSLK L +K VEY +DDS++KL S CPVLE+L I    RD   ++  VS P LK LR+ F +         +D +Y + ++AP LE L                       D++QD                  IY L      ++C             CP   P F  +T L+ +    + WD L   L  SPNLE+ VIE
Sbjct:    7 ESRDIISNLPDELLCHILSFLPTKFAVGTSILSKRWRYLWASVPILDFDDELWLNPSTLVELEERIIMFQNFVDGVLRHSEVSCIKKFRL------------------GYRDN-----------NLDNWGVELPPMFFICKTLVVVKL-SCALFLDIPTTVWLPSLKALHLKSVEYSDDDSIQKLLSGCPVLEELVIEREERDNQWVV-NVSNPSLKILRIFFFTDGFAHPYEQEDQDYKVVVDAPNLEYLSITDYLSKDYFVKDLPSLVKAFIDVEQDSEEFEESPHNGGISYHGPIYELLGRISNVKCLSLTGVTLDVSFLCPPILPTFHNMTCLEFLFIGGFNWDFLPNFLHSSPNLEALVIE 341          

Query:   34 KDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSI--YGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRD---SLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYLECCPPAFDQLTQLKLVLYDCY-RWDLLTQLLKKSPNLESXVIEN 945
            +DRIS LPD +L  ILS +PTK   RTS+LS  W+ +  + S+  L F+      + ++ +  +   F+  +D  L LR    SL   + RLH     E  S I  WI  A+   V ELDL +   +I    + LP  +F   T+ VL ++       +      P+L+ L ++    ++ ++ +L S CP++EDL I             VS  +LK+L ++ ++       H   ++     L  ++I    L  +++++ + L C           +L+L+D +   DLL  L+   PNLE   I++
Sbjct:   37 QDRISYLPDDILIRILSLLPTKEIARTSLLSKAWRKLSPFSSLSVLMFQSPDFFHSRRKNF--DVSSFINAIDSSLRLRQKDVSLARLQLRLH-LNDIESESLIDSWIDAALERKVKELDLYLLPRSIP-EPYGLPAKIFSTTTITVLSLEQ--CRLEICGDVDLPALRKLCLRKILCDEQAIRQLISSCPLIEDLDI-------------VSCGKLKKLHVSGLANL-----HRLVVTC-CYNLRRIEIDAPSLQYFMYDHQRSLLCDVVWTPGEFLRELILHDRHITNDLLQNLVSGVPNLERLEIDS 321          

Query:   25 AKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSI--YGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLR-DSLDIQKFRLHC-YXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRL-RMTFVSAYLVSKDHEYDISINAPKLENL 762
            A+ +DRIS LPD +L  IL  +PTK   R+S+LS  W+ +  + S+  L F+      + ++   ++   F+  +D  L LR   +++ + RLH      E  S I  WI  A+   V ELDL +   +I    + LP  +F   T+ VL ++       +      P+L+ L ++    ++ ++ +L S CP++EDL I +        + K+    L  L R+  +  Y + +     I I+AP L++L
Sbjct:    2 AEEQDRISHLPDDILIRILGLLPTKDVARSSLLSQAWRKLSPFSSLSLLMFQCPDFLESCRKN--TDVSSFINAIDSSLRLRPKDVNLARLRLHLDLDDIESESLIDSWIDAALERKVKELDLYLRPRSI-AKPYGLPAKIFSTTTITVLSLEQ--CRLEICGDIDLPALRKLCLRQIRCDEQAIRQLISSCPLIEDLDIASCGG-----LQKLHVSGLANLHRLEVICCYNLRR-----IEIDAPSLQHL 237          

Query:   10 KSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQM--------STTWKEEYMSNYVGFLMFVDRVLSL----RDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNV--VELDLCVY------SDNIVCXTFELPQCVFMCK---------TLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISI-------------NAPKLENLDIK-------------------QD--------CLSIYLFENFKYLECCPPAFDQLTQLKLVLY-----DCYRWDLLTQLLKKSPNLESXVIE------NKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            K+    +G+D + ELPD +L  I+S +P K +VRT ILS RW+SI+     L F+   +        S +  +  +++ +    FV+RV            I  F +H     E  S I  WI  A+   V  ++LDL  Y       D+     F++ +  F C+         TL  L++ S C    LP+S    SL  +D++     D  ++ L S C  LE LS+      L+ L F     +LK L +         + H  D+               N PKL    ++                   QD         LS+   +  +  E   P F  + Q +L ++     D   W  +  +LK  P L+   +        K+ +E  +          +P C   HL  + I GF G  H   + KYLL N   L  + V
Sbjct:    7 KAAKLVRGEDWLVELPDDILSTIISLLPLKEAVRTGILSKRWRSIWTCHSELWFDAASVLGIGDCSTSMSGNQPELNSQMQSSKFVERVDQFMYYRSQGRKINSFSIHFPLGKEFMSHIDQWITCAVMKGVENIDLDLSEYFSFNLKRDDTSSTAFQIYE--FPCRLFSVPGGRCTLKHLRLAS-CHLSALPSSNTLTSLITVDLQRVNISDQQLQDLLSTCSHLEWLSL-CVCNGLVNLSFSALNLQLKFLSIKNCFRLETIEIHAADLVTFKYGGHLPSFSFKNVPKLAKASLEFFIKSSRTEGVMYALTRFPQDLPQLETLKLLSVLTLKKLQLPE-NGPTFTNVKQFELTVFPFDDDDDLSW--IGYILKAFPLLQKLELNLFSPSFTKQPKEIER---------FLPECPHRHLSILQINGFYGNQHEVDLLKYLLHNLVALELLVV 442          

Query:    7 SKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRD-SLDIQKFRLH--CYXRXEDFSR----IVGWICTAIRHNVVELDLCVYSDNIVCXTFE---------LPQCVFMCKTLVVLKVK-SNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSIN 615
            S+ N +    DRISELPD VL HILSF+P   ++RT +LS R+   + S PNL F+     + W+ +       F+ FV+R L L D +  +QKF ++  C  +  + S     +  W+  A R  V +L+L    +      +E         LPQ +F   +   L  +  N +TYG+ +   +  LK L +      ++++  +    P LE L  +
Sbjct:   25 SRKNPRESRVDRISELPDLVLVHILSFLPMDAAIRTGVLSKRFAYKWASTPNLVFD---QDSEWEID------DFITFVNRALLLHDPNCKVQKFTIYMDCMDQVIENSLQEDCVTLWLRFATRKGVEKLNLGFNDEEDPLQLWESRYDSYRYLLPQFIFRHSSFRKLATRFCNFVTYGVVS---WAWLKSLSIGYAELNEETIRNILMGSPALECLEFH 232          

Query:   97 KYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCV-----YSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVS--KDHEYDISINAPKLENLDI 768
            KY V TSILS RW+ ++  VPNL F F +     ++E+      F+  +D+ L L  +  I+KF +    + +  S +  WI  A R NV EL L          + +     LPQ ++   ++V L +    I      S  +PSLK L +      DD +E++ S CP LE L ++       +    +++  LK+L    ++ Y  S    H   + I+AP +++L I
Sbjct:    2 KYVVATSILSKRWQFLWTMVPNLVFRFRR-----RDEH------FVNSIDKTLVLHQNSQIKKFLIDFTYQSQFQSSVNVWIRHATRKNVEELHLQFRVGQHIRSSPMDYAHALPQFLYANSSIVKLSLWFCNIKPTWVIS--WPSLKTLSIGSVELCDDLIEEILSGCPALESLELHHCFG---INSLNITSASLKKL---VINRYWDSSHSHHRSVLKISAPNVQSLGI 213          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTS----GCFPSLKFLDVK-VEYPEDDSMEKLF--SCCPVLEDLSINA------------TVRDLLVLM------FKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKL 753
            DRI+ LPDAVL  IL  +P K   +TS+ S          PN +   + +S T       + +       RVL         +FR H       FSR+ G I +AIRHNV +LD+ V +D+     F LP+CV M ++L  L +K     + LP S    G F SL+ L +  + + +   +  LF  S  PVL  L++++             ++DL V          VS P L+RLR+  VS +  S +  + + I AP+L
Sbjct:   23 DRITHLPDAVLHQILLLLPIKTIAQTSVFSVS--------PNPN-TLDCISQTLAAHQRGSDI-------RVL---------RFRAHL-----GFSRLNGLIRSAIRHNVQDLDIDVCTDDY----FNLPRCVVMSESLKALSLKFRPPGFRLPPSMVMRGGFQSLQTLSLSHMVFYKKHYLLDLFAGSAFPVLRKLTLDSCRGIKFLDVGCRVLQDLTVENCFQLHGLTVSGPRLERLRV--VSCFESSSEKSW-VKIIAPRL 249          

Query:  337 WICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-----------------TFVSAYL---VSKDHEYDISIN-------APKLENLDIKQDCLSIYL------------FENFKYLECCPPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEEC---VKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            WI    R++V E+ L +      C  F +P C+F C+ L  L++   C  +  PT   F  LK L++       ++++ L S CP+LE LS++    D L L   +SAP LK L +                   V+ Y+   V +  E   S N       AP LE L I     + +L            + + K +E    +F+ + ++ ++L          +L+  SPNLE   I    +      V D   W   E    C    L+T+ +    G PH  +  K+LL+N  +L  M++
Sbjct:   77 WILFLSRNDVKEILLELGE----CEWFTVPSCLFSCQKLTRLELV-RCELHPPPTFKGFLHLKILNLHQVSITCEAIQSLVSSCPLLECLSLSYF--DSLAL--NISAPNLKYLFLEGEFKEICLENTPGLVSVTVAMYMSDDVVEHFEQSSSCNFIKFFGGAPHLERL-IGHIYFTKFLSIGNELGRHPITYHHLKNIELYQVSFEDIKEILVIL----------RLIIYSPNLEELQISGSSNTSVSPEVLDLDFWEN-ECPLDCAFKCLQTVKMTDISGLPHEMRFIKFLLENSPILEIMSI 360          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSI--YGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRD-SLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVY-SDNIVCXTFELPQCVFMCKTLVVLKVK 471
            D+IS+LPD +L  ILS +PT+   RT+++S  W+ +  + S+P L F+         ++  ++   F+  +D  L LR     ++K RLH +    + S I  WI  A+   V ELDL +          + LP  +F    + VL ++
Sbjct:    7 DQISQLPDDILRSILSLLPTRDLARTNLVSKAWRKLFAFSSLPILMFKSSDFLVAPCKD--TDVSSFINAIDSYLKLRQKDASLEKLRLHVHLNDVE-SLIDSWINAALERKVKELDLFILPRGRARRKPYSLPAKIFAAIKITVLSLQ 152          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQ-KFRLHCYXRXEDFSRIVGWICTAIRHNVV---ELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDL-----------SINATVRDLLVLMFKVS-----------APELKRLRMTFVSAYLVSKDHE--------YDISINAPKLENLDIKQDCLSIYLFENF----KYLECC------------PPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPN---LESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXG-YPHVKKVAKYLLKNGKVLTKMTV---------XNDELYKELMLE-RGSRTCWV 1185
            D+ S+LPD +L  +LSF+PTK +VRTS+LS RWKS++  +P L+++F   S + + + ++ ++   +   +  ++ +SL ++ ++      + ED   I  W+  A+  + V    L LC +++       +LP+ ++ CK++V+LK+K   I   +P   C PSLK L + +V Y ++DS+ +L S CPVLEDL            ++  V+ L  L  K+S            P LK L++T       S +          YD   + PKLE  D      +I  F  F    K L  C               F+QL QLK+   D     LL++LL+ SPN   LE+ VIE+  D               VP CL+S L+T       G   +   VAKY+L+N + L   T+           DE+ +EL L  +G  TC V
Sbjct:    2 DKTSQLPDELLVKVLSFLPTKDAVRTSLLSMRWKSLWMWLPKLEYDFRHYSVS-EGQGLARFITLSLLGHKAPAI-ESLSLKLRYGAIGSIKPED---IYLWVSLAVHDSNVRELSLKLCTFAER----PTKLPKSLYKCKSIVILKLKDE-ILVDVPRKVCLPSLKTLFLGRVTYSDEDSLHRLLSNCPVLEDLVVERDRIDNLGKLSVVVKSLQRLTLKMSCPCHLDGIMMNTPSLKYLKVTDERQESDSDNESDSDSPRYFYDFE-DMPKLEEADFVLTFQNIKKFFKFVTSIKRLSLCLGVYTEESLYHEGLVFNQLEQLKICSCDSDWSILLSRLLESSPNLRELEAYVIEDHPDRRVDLPNQWGNQLNCVPKCLLSSLETFKWSEMYGLLQNQMDVAKYILRNARCLKSATIFFPTTYAKETRDEMIEELSLSFQGPETCQV 438          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCY---XRXEDFSRIVGWICTAIRHNVVELDLCVYS--DNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDLSINA----TVRDLLVLM------------------FKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCL----SIYLFENFKYLECCPP-------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYG----KWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND---------ELYKELMLERGSRTC 1179
            D+I+ LPD +L  ILS++PT  +V TSILS RW+ ++  +PNLD+     ++ W  +     VG   F+ + L L  +  I+  R H      + ED  R   WI  A+  +V +LD+  +S  +NI   +F      F CK+LV LK++S  +   +P+  C PSLK L +  V + E  S+++L S CPVLEDLS+        ++L +++                  + +  P L+ L++   +    S DH   +  N PKL    +   C      I    + K+L  C          F+QL  L L +       LL QLLK SPNL   ++E    E+ V D G     W    SVP CL+S L+      + G P  + +A Y+LKN + L K T+  D          + KEL+    +R C
Sbjct:    2 DKINGLPDDLLVKILSYVPTDIAVSTSILSKRWEFLWMWLPNLDY-----TSRWCRK--PGDVGLRDFIHKNLPLHRAPVIESLRFHSNSPDIKPEDIRR---WIEIAVSRHVHDLDIDHFSENENIFLSSF------FACKSLVTLKLRSVTLR-DIPSMVCLPSLKTLLLDNVSFVEGKSLQELLSICPVLEDLSVYCDDYENTKELTIVVPSLLSLSLYIPDEWLLDGYWIDTPSLEYLKLEDWN----SCDH-LSLIKNMPKLREAYVDAKCFLPKSVIESITSVKHLTICSKDGYGDGFVFNQLEHLTLCVCRGDSPSLLGQLLKDSPNLR--ILEISVMEDHVDDVGISLDGWNQPSSVPECLLSSLQIFKWPQYLGRPEDRDIAVYILKNARHLKKTTILADRCERFVTQRRMIKELLQALPARIC 410          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRL---HCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-------------TFVSAYLVSK-DHEYDISI-NAPKLEN-------LDIKQDCLSIYLFENFKYLECCPPA-------FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND-------ELYKELML-ERGSRTC 1179
            DRIS LPD VL  ILSF+PTK +V TSILS RW+ ++  +  L F  ++ S        S +     F+DR L L  +  I+ FRL     + + ED   I  W+  A+   + EL   +YS +       LP  ++ CK+LV+LK+    +   +P   C PSLK L++K V Y +  S+++L   CPVLEDL +N +  D +  +  V  P L+RL +             + +S  LV + D+ +   I N PKL          DIK    SI    + K L             F+ L +  L L++ Y  +LL   LK SPNL   ++ ++ D+        W     VP C++S L+  T   + G P  + +A Y+LKN   L   T+ +D       E+  EL L  + S TC
Sbjct:    2 DRISGLPDEVLVKILSFVPTKVAVSTSILSKRWEFLWMWLTKLKFGSKRYSE-------SEFKRLQCFLDRNLPLHRAPVIESFRLVLSDSHFKPED---IRMWVVVAVSRYIRELK--IYSSHYGEKQNILPSSLYTCKSLVILKLDGG-VLLDVPRMVCLPSLKTLELKGVRYFKQGSLQRLLCNCPVLEDLVVNLSHHDNMGKL-TVIVPSLQRLSLSTPSSREFVIDTPSLLSFQLVDRNDNSHTFLIENMPKLREAYINVPFADIKSLIGSI---TSVKRLAISSEVGYGEGFIFNHLEE--LTLWNKYSSNLLVWFLKNSPNLRELMLVSETDDHENLGMLSWNQPSIVPECMLSSLQKFTWFKYLGRPQDRDIAVYILKNACRLRTATIKSDTRLFTKLEMITELRLSSQASSTC 404          

Query:   31 GKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVS-APELKRLRMT-----------FVSA----YLVSKDHEYD-ISINAPKL------ENLDIKQDCLSIYLFENFKYLECCPP---------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDY------GKWRTTESVPICLISHLKTITIRGF-XGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            GKDRISELPDA+L  ILSF+PTK  V TS+ S +W+ ++  VPNL+F+ E      KE+Y  + +    F+     + +S     FRL       D   I  W+  A   ++ EL L V +D      F+ P  +  C TL  L++    I   + +     SL+ L ++ V Y ++ S+  L S CP+LE+L +     D  + +F +   P LKRL +             ++A    YL+ +D       +NAP+L      +   I  D    YL    + L    P          F QL  L++   +   WDLLT +L+ SP L+      K  + CVK +      GKW   + VP CL+SHL+T   R F  G    K++A Y+LKN + L K T   + +  E
Sbjct:   14 GKDRISELPDALLIKILSFLPTKIVVATSVFSKQWRPLWKLVPNLEFDSEDYDD--KEQYTFSEIVCKSFLSHKAPVLES-----FRLEFESEKVDPVDIGLWVGIAFSRHLRELVL-VAADTGTGTAFKFPSSLCTCNTLETLRLVL-LILVDISSPVVMKSLRTLHLELVSYKDESSIRNLLSGCPILEELLV-IRGEDSDIEVFTIDEVPSLKRLTINDDHDGQEFWGYVINAPSLKYLLIEDLRCPGFCLNAPELMEANIFDGTSITNDNFLGYLTSVKRLLLNLSPWKITYPTGSIFYQLVSLEMYTREIDWWDLLTLMLEHSPKLQVL----KLTDNCVKFHKNGLPGGKWNEPKYVPECLLSHLETFVWRRFDWGREEEKEIATYILKNARRLNKATFSTNPVNSE 412          

Query:   31 GKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRI-VG-WICTAIRHNVVELDLCVYSDNI-VCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM----------------TFVSAYLVSKDHEYDISINAPKLENLDIKQ-DCLSI-----------YLFENFKYLECCPPA---FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKD---YGKWRTTESVPICLISHLKTITIRGF-XGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            GKDRISELPD +L  ILS +PT   V TS+LS +W+S++  VPNL+F+         ++Y S +  F   V +      +  ++ FRL    +  +F+ + +G W+  A   ++ EL L  Y   +    TF  P  +  C TL  LK+   CI   +P+     SL+ L ++ V Y ++ S+  L S CP LE+L +     D  + +F +  P L+RL +                 F+   L+ +    +  +NAP+L   +I +   ++I            L  N   L+   P    F QL  L++   +   W+LLT +L+ SP L+   + ++  +   KD    GKW   + VP CL+S L+T   R F  G    K++A Y+LKNG+ L K T   + +  E
Sbjct:   19 GKDRISELPDGLLLKILSSLPTNIVVATSVLSKQWRSLWKLVPNLEFD--------SDDYESEHYTFSEIVCKSFLSHKAPVLESFRL----KFVNFNPVDIGLWVGIAFSRHLRELVLDFYPAELGKGVTFTFPSSLCTCNTLETLKLVL-CILVDIPSPVLMKSLRTLHLEFVRYKDESSVRNLLSGCPGLEELRLYRG-DDSDIKVFTIEVPSLQRLTIHDNNDGPEFWGYVINAPFLKYLLIEELRCPEFCLNAPELVEANIAEVTSITIEKFLGSFTSVSRLLLNLSPLKITYPTGSMFYQLVSLEMYTREAEWWNLLTLMLENSPKLQVLKLTDR-SQNFHKDGLVSGKWNEPKDVPECLLSQLETFVWRRFDWGREEEKEIATYILKNGRRLKKATFSTNPIESE 415          

Query:    1 MCSKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTF-ELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-------------TFVSAYLVSKDH--------------EYDISIN---APKLENLDIKQDCLSIY------------LFENFKYLECCP-PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRG-FXGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            +C K +SQ   ++R+S+LPD ++C ILS + TK +VRTSILSTRW++++  VP LDF+  +         + ++  F+ F      L     IQK R+  Y    ++  +  WI    RH +  +D+ V++    C  F  +P  ++ C TLV LK+    +T         P LK LD+  V +  + +++K+ SC PVLE+L+I  +  D  V + +V +  LKR+ +             T +  +L  K H              + DI +N      L N  + +D  +              + + F Y+E  P   F  L++L  V       ++L  LLK  P LES  ++  + E+  K+  +  ++   P CL+S LK + +     G     KVA+Y L+N  +L K+T+  D +YK+
Sbjct:    6 ICGKGSSQGSEEERLSQLPDHLICVILSHLSTKDAVRTSILSTRWRNLWQLVPVLDFDSRE---------LRSFSEFVSFAGSFFYLHKDSYIQKLRVCIYDLAGNY-YLTSWIDLVTRHRIQHIDISVFT----CSGFGVIPLSLYTCDTLVHLKLSR--VTMVNVEFVSLPCLKILDLDFVNFTNETTLDKIISCSPVLEELTIVKSSED-NVKIIQVRSQTLKRVEIHRRFDRHNGLVIDTPLLQFLSIKAHSIKSIEFINLGFTTKVDIDVNLLDPNDLSNRSMTRDFFTTISRVRSLVIRHGTIKDIFHYMELEPLQQFCYLSELSAVC-SISNLEMLLNLLKSCPKLESLSLKLVDYEKNKKE--EVMSSTVPPPCLVSSLKFVKLESQLLGCGTELKVARYFLENSTILEKLTLKIDYMYKD 414          

Query:    4 CSKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVE-YPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDIS---INAPKLENLDIKQDCLSIYLFEN-----------------------------------------------------FKYLECCP----PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTT-ESVPICLISHLKTITIR-GFXGYPHVKKVAKYLLKNGKVLTKMTV----------XNDELYKEL-MLERGSRTCWVELV 1194
            CSK  +Q   +DRIS+  +++LC IL+++PTK  V+TS+LSTRW+S++  VP+L+ +             S++  F+ F DR       L I K +L      ED   +  WI  A +  +  LD+       +    ++   ++ C+ LV L++    +  G   S  FP +K + ++   YP + + ++L SCCPVLEDL++     D  V  F+V +  LKR  +  VS++L    HE  +S   I+AP L +L I  +    ++  N                                                     ++YL   P    P F  +++L + L        L   L+  PNL+S ++E+  + + +   G +     SVP CL+S L+ + I+     Y    K+ KY L+N   L K+T+            DE+ K+L    R S+TC V +V
Sbjct:   11 CSKGLNQRLKEDRISQFYESLLCQILNYLPTKDVVKTSVLSTRWRSLWLLVPSLELDSRD---------FSDFNTFVSFCDRYFDSNRVLCINKLKLTISENEEDGFYLKSWIDAAAKRKIQHLDV-----QFLPQFHKIHFNLYKCEALVSLRLFEVSLDKGRIFS--FPCMKTMHLEDNVYPNEATFKELISCCPVLEDLTVIIYGMDRKV--FQVHSQSLKRFSLKRVSSFL----HEVALSGVVIDAPLLCSLRINDNVSKSFIVNNLGSNDKLDLSILFGLWHFDETSVTSMRSSIDRFLPGILSVMEMTIHSPAFMLMYRYLALIPLPHLPKFSYMSRLSVTL-GVSDLQFLPTFLESCPNLKSLIMESNSNSKRMLLNGNYHINFSSVPKCLLSSLEFVDIKSSILVYVARMKLVKYFLENSTTLKKLTLRLALRLQYCSAKDEIVKKLRKFPRISKTCQVGIV 458          

Query:   34 KDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLH----CYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLD-VKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENF-------------------------KYLECC-------PPA---FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVL---------TKMTVXNDELYKELMLE-RGSRTC 1179
            +DR+S+LPD  L  ILS++PTK  + TS+LS RW+ ++  VP L+++      T           F  FVDR L L  +  ++   +     C+   +D   +  W+   +   V EL +   S         LP+C+F C TL VLK++ N          CF SLK L  + V+Y +D S+ ++ S C  LEDL +     D  V +  V+AP LK L +   S      D  +   I+ PKL+ +DI+         EN                          K L  C        PA   F QL  L+L       WDLLT+L++ SP L    +  K           W+   ++P CL+ HL+T     + G    K+VA ++LK+   L         T   +   E+ K+L    RGS TC
Sbjct:    5 RDRLSQLPDDFLLQILSWLPTKDVLVTSLLSKRWRFLWTLVPRLNYDLRLHDNTCPR--------FSQFVDRSLLLHKAPTLESLNIKIGSICFTAEKD---VGVWVRIGVDRFVRELSVSYCSGE---EPIRLPKCLFTCSTLAVLKLE-NITLEDASCYVCFQSLKTLHLLDVKYLDDQSLPRIISSCSSLEDLVVQRCPGD-NVKVVTVTAPSLKTLSLHKSSQAFEGDDDGF--LIDTPKLKRVDIEDYWGGFCYIENMPEVVEANVDVIYKNTEKLLGSITSVKRLALCLITSDAAYPAGTIFSQLVHLELCTCAPRWWDLLTRLIEDSPKLRVLKLRQKHIRRAPSPRASWK-QPALPKCLLFHLETFKWELYEGSQKQKEVATFILKHAIRLKTAIISPKPTSTLLEKHEMLKDLSSSPRGSSTC 417          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSI-----NATVRDLLVLMFKVSAPELKRLRMTFVSAYL----------VSKDHEYDISI--NAPKLENLDI---------KQDCLSI------YLFENFKYLEC-CPPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDY--GKWRTTE-SVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            DRIS LPD +L  I+SF+PTK +V TSILS RW+S++  VP L+ +  + +   ++  + N    L    R++   +SL + +FR   +     F  I  W   AI H + EL +  +S +       LP+ ++ CK+LV LK+    I   +P   C PSLK L ++ V Y E+D +  L SCCPVLEDL I     N  V+ L+V++  +    LK         YL          V  D E   ++  N P+LE  DI          +   S+       L+ +    +C     F QL QL+L +       L+  LL+ SPNL    ++   D E  ++Y    W+  + SVP CL S LKT+   G+   P  +    ++ K  + L   ++
Sbjct:    2 DRISGLPDELLVKIISFVPTKVAVSTSILSKRWESLWKWVPKLECDCTEPAL--RDFILKN----LPLQARII---ESLYL-RFRRESFL----FQDIKLWGGIAISHCLRELRIDFFS-HYANPYVILPRSLYTCKSLVTLKLLGLGIRVDVPRDVCLPSLKTLLLQCVAYSEEDPLRLLLSCCPVLEDLVIELDDANQNVKALVVIVPTLQCLSLKIPASCSDERYLIVTPSLKYFKVEDDREIFNALIENMPELEEADIYVTQHIETLLESVTSVKRLTLRQLYNSIDEYKCRAGIVFKQLEQLELSICSDNWTKLVIWLLQNSPNLRVLNLDADSDYERYEEYEQDNWKNIQRSVPKCLKSSLKTLEFAGYTARPEERDFLSFIFKKARCLKTSSI 386          

Query:    4 CSKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLH----CYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISI-NAPKLENLDIK------QDCL---------SIYLFENFKYLECC----------------------PP---AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXG-YPHVKKVAKYLLKNGKVLTKMTVXNDELYKELMLE 1161
            C         +DRIS+LP+A+L  ILS +PTK  V  S+L+ RW+ ++  VP+L+F +          + ++   F   V + L    +  +Q   L+    C  R  DF  ++G    A    + +L L VYS +     F+ P  ++  +TL  L++  +CI   +P   C  SL+ L++ +VE+  D+S+  L + C  LE+L I+ T  DL V  F ++ P L+RL +      +V    E+ + + N P L+ L I+      + C+         +  +  +FK  E                        PP    F  LT L+L  Y    W+LLT +L  SPNL+   I +    +  + + KW   ++VP CL+ HL+T     + G   +  ++AKY+L+N + L K T    E+  +  +E
Sbjct:    6 CKSCGQSLSNEDRISQLPEALLLQILSLLPTKEVVAVSVLAKRWRFLWKMVPSLEFFYY---------FTNDLERFSYNVSKCLFSHQAPFLQSLHLNMNFGCDPRIMDFEILIG---IAFGRQLRKLVLKVYSGD----WFKFPTSLYNSETLETLELY-HCILIDVPFPVCLKSLRTLNLHEVEFVNDESVVNLLAGCISLENLVIHQTT-DLNVKTFTIAVPSLQRLTV------IVEYYEEFSVFVVNTPSLKYLKIEGIIVDDRTCIIENTPELVEASIIDVSFKVFESILGSLASVQRLSLKVSLVEIFSLPPISNTFYHLTYLELSTYKPKWWNLLTLMLDTSPNLQVLKIFDFMTSQEQRPWEKWNEPKNVPECLLLHLETFVWTCYEGKLENEIELAKYILRNARRLKKATFSIIEINPDKRVE 414          

Query:   28 KGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFE-QMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLV----SKDHEYDISINAPKLENL-----------------------DIKQDCLS---------------IY----LFENFKYLECCPPAFDQL---------------TQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXNDELY---------KELMLERGSRTCWV 1185
            + +D IS LPD +LCHILSF+PTK++V TSILS RW+ ++ SVP LDF+ E  ++ +   E     + F  FVD VL   +   I+KFRL    R  +   +  WIC A+   V ELDL +  D       ELP   F+CKTLVV+K+ S  +   +PT+   PSLK L +K VEY +DDS++KL S CPVLE+L I    RD   ++  VS P LK LR+ F +         +D +Y + ++AP LE L                       D++QD                  IY       N K L       D L               T+L+ +    + WD L   L  SPNLE+ VIE     E + +   W     VP CL+ HLK I IR   G  +  +  +YLLKN +VL +MT+   E Y         K L L RGSR+C+V
Sbjct:    7 ESRDIISNLPDELLCHILSFLPTKFAVGTSILSKRWRYLWASVPILDFDDELWLNPSTLVELEERIIMFQNFVDGVLRHSEVSCIKKFRLG--YRDNNLDSVYSWICIALERRVQELDLHLLID----WRVELPPMFFICKTLVVVKL-SCALFLDIPTTVWLPSLKALHLKSVEYSDDDSIQKLLSGCPVLEELVIEREERDNQWVV-NVSNPSLKILRIFFFTDGFAHPYEQEDQDYKVVVDAPNLEYLSITDYLSKDYFVKDLPSLVKAFIDVEQDSEEFEESPHNGGISYHGPIYELLGRISNVKCLSLTGVTLDSLSGTIGDYKLPTFHNMTRLEFLFIGGFNWDFLPNFLHSSPNLEALVIETGYTNELIPE--GWLMPLQVPACLVLHLKEIEIRRIVGEDYELEAVEYLLKNAEVLQQMTIDCHESYMDQEFCVCKKLLGLPRGSRSCFV 454          

Query:   16 NSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMS-NYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLV------------------------------------SKDHEYDISINAPKLENLDIKQDCLSIYLFENFK-----YLECCPPAFDQLTQLKLVLYDCYRWDLLTQLLK-KSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            ++  K +DRIS LPDAVLCHI+SF+PTK++V TS+LS RW+ ++ S+PNLDF+ + +    K    S   + F  FVD+VL       I+KFRL C     D S +  WICTA+  NV ELDL   ++       ELP   F CKTLVVLK+ S  I   +P+   FPSLK L ++ VE+  DDS +KL S CPVLE+L I     D    +F VSAP LK L + F    L                                      +D +Y + ++AP LE L I       YL  N       Y+   P       Q   +LY    ++LL  +   K  +L    +   +D EC  +  +W     VP C+  HL  + I+ F G  +     ++LLKN +VL KM++
Sbjct:    3 STYGKSRDRISNLPDAVLCHIISFLPTKFAVGTSVLSKRWRYLWASIPNLDFDDDLLLDRDKPIGDSERSICFKNFVDKVLLHGSISCIRKFRLKCSDHELD-SAVNSWICTALERNVQELDLYFDTE----YPIELPPKFFFCKTLVVLKL-SFSIFLDIPSLIWFPSLKVLHLRSVEFSTDDSAQKLLSSCPVLEELVIERWRLD-EQWVFNVSAPTLKSLAIYFSVDGLACIAEREDELVDELDNELLVVPQVGPEDESEDEAEDEPEDQKYKLVVDAPNLEYLSITDFVSEDYLMSNLSSLVKAYVNVGPTIRGIDDQ---ILYRGRIYELLRGISNVKHLSLSGETLHVNKD-EC--EIEEWTLPLQVPTCVELHLNEVEIKKFDGLDYELGAIEFLLKNARVLKKMSI 403          

Query:   28 KGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFE-QMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLV----SKDHEYDISINAPKLENL-----------------------DIKQDCLS---------------IY-LFENFKYLEC-------------CP---PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIE 942
            + +D IS LPD +LCHILSF+PTK++V TSILS RW+ ++ SVP LDF+ E  ++ +   E     + F  FVD VL   +   I+KFRL    R  +   +  WIC A+   V ELDL +  D       ELP   F+CKTLVV+K+ S  +   +PT+   PSLK L +K VEY +DDS++KL S CPVLE+L I    RD   ++  VS P LK LR+ F +         +D +Y + ++AP LE L                       D++QD                  IY L      ++C             CP   P F  +T L+ +    + WD L   L  SPNLE+ VIE
Sbjct:    7 ESRDIISNLPDELLCHILSFLPTKFAVGTSILSKRWRYLWASVPILDFDDELWLNPSTLVELEERIIMFQNFVDGVLRHSEVSCIKKFRLG--YRDNNLDSVYSWICIALERRVQELDLHLLID----WGVELPPMFFICKTLVVVKL-SCALFLDIPTTVWLPSLKALHLKSVEYSDDDSIQKLLSGCPVLEELVIEREERDNQWVV-NVSNPSLKILRIFFFTDGFAHPYEQEDQDYKVVVDAPNLEYLSITDYLSKDYFVKDLPSLVKAFIDVEQDSEEFEESPHNGGISYHGPIYELLGRISNVKCLSLTGVTLDVSFLCPPILPTFHNMTCLEFLFIGGFNWDFLPNFLHSSPNLEALVIE 364          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSR---IVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISI-------------------NAPKLENLDIKQDCLSIYL------FENFKYLECCPP-------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVK--DYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMT---------VXNDELYKELML-ERGSRTC 1179
            D +S LPD +L  ILS +PTK  V TSILS RWK ++ S+P L+F     S    +           FV++ L L  +  IQ F L  Y   E   +   I  W+  A+  ++ ELD+   SDN       +P  +F CK+LVVLK++   +   +P++ C PSLK L ++ V Y +    E L S CPVLEDL +     D  +  F ++ P L++L +    +Y  S    Y+I                     N PKLE   +  D +S  +        + K+L  C          FDQL  LKL +      ++L Q LK SPNL   VI   +    +K  + G W    SVP CL+S L+ +   G+ G P  + +A Y+L+N + L   T         V N E+ KEL L  R S TC
Sbjct:    2 DNLSRLPDELLVRILSLVPTKVVVSTSILSKRWKFLWMSLPKLEFVDRDESLLVLKN----------FVNKNLPLHRAPVIQSFLLSLYESREKNIKPEDIRQWVEIAVSRHLRELDVSYSSDN---KENMVPNSLFACKSLVVLKLRFLTLM-DVPSTACLPSLKTLLLELVVYEDQKPFEALLSICPVLEDLEVWFR-EDESIQEFTINVPSLRKLCLHV--SYYWSSLERYEIDTPCLEYLELADWNDSPCLVKNMPKLEKAHV--DVVSFAVKNVIGSVASVKHLTVCSEDVYGDGIVFDQLEHLKLCICKDDSSNVLAQFLKDSPNLRVLVISQLDLHADLKTNEMGYWNQPSSVPECLLSSLQILNWEGYFGRPQDRDIAVYILRNARHLRTATIWGNTVEHDVPNLEMIKELTLSSRASSTC 411          

Query:   22 QAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLS-LRDSLDIQKFRLHCYXRXEDFS----RIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNC-ITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLE--DLSINATVRDLLVLMFKVSAPELKRLRMTF---VSAYLVSKDHEYDISINAPKLENLDIKQ----DCLSIYLFENF--KYLECCPPA-------------------------------------------FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXNDEL 1140
            + + +DRIS LPD VL HILSF+PTK SV T+ LS+RW+ ++  +  L F  +  S  + ++    +  F + V+ VL+ LR+   IQK  L C     D       +  W+  AI  ++ EL+L ++ D      F+LPQ +F C  LV L +     ++    T+   PSLK L + + Y E  S+  L   C  +E  DL  +A   D + +      P LKRL++T    V AYL          +NAP L+ L+I Q    +  S+Y   N    YL+  P +                                           F  L +L+LVL   +  + L  L++K P L+  +I+N ++   +     W    S+P CL+SHL  I  +GF G+P      +Y+L+NG VL  + + +  L
Sbjct:   14 EEENEDRISYLPDGVLNHILSFLPTKTSVSTARLSSRWRHLWQHLSVLHFSDD--SHEYVDQPAERFKSFALLVNGVLALLRNPRAIQKMSLSCVHSFTDDKFREYSVETWVRAAIGPHLHELELTLFCDE-DAPDFKLPQALFSCPNLVSLSLSGAVHVSIQHSTAVSLPSLKMLMIDIGYVEVSSVNALLDGCSSIEILDLGFSAQSLDKVCV-----PPSLKRLKITIENDVGAYL---------EVNAPDLQYLNITQITFGEGFSLYSLPNVVEAYLDVFPTSLGSIVPLHNLFGALSGAKHLMLSRSTTKVKWLLGEPHEMLFQEFQYLIRLELVL-SWFNSNSLLHLIQKCPLLQPLIIQNDKERSPIL---AWSPQPSIPNCLVSHLSFIEFKGFRGFPDEVSFVEYVLQNGHVLKTLIIADISL 425          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRL---HCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-------------TFVSAYLVSK-DHEYDISI-NAPKLEN-------LDIKQDCLSIYLFENFKYLECCPPA-------FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND-------ELYKELML-ERGSRTC 1179
            DRIS LPD VL  ILSF+PTK +V TSILS RW+ ++  +  L F  ++ S        S +     F+DR L L  +  I+ FRL     + + ED   I  W+  A+   + EL   +YS +       LP  ++ CK+LV+LK+    +   +P   C PSLK L++K V Y +  S+++L   CPVLEDL +N +  D +  +  V  P L+RL +             + +S  LV + D+ +   I N PKL          DIK    SI    + K L             F+ L +  L L++ Y  +LL   LK SPNL   ++ ++ D+        W     VP C++S L+  T   + G P  + +A Y+LKN   L   T+ +D       E+  EL L  + S TC
Sbjct:    2 DRISGLPDEVLVKILSFVPTKVAVSTSILSKRWEFLWMWLTKLKFGSKRYSE-------SEFKRLQCFLDRNLPLHRAPVIESFRLVLSDSHFKPED---IRMWVVVAVSRYIRELK--IYSSHYGEKQNILPSSLYTCKSLVILKLDGG-VLLDVPRMVCLPSLKTLELKGVRYFKQGSLQRLLCNCPVLEDLVVNLSHHDNMGKL-TVIVPSLQRLSLSTPSSREFVIDTPSLLSFQLVDRNDNSHTFLIENMPKLREAYINVPFADIKSLIGSI---TSVKRLAISSEVGYGEGFIFNHLEE--LTLWNKYSSNLLVWFLKNSPNLRELMLVSETDDHENLGMLSWNQPSIVPECMLSSLQKFTWFKYLGRPQDRDIAVYILKNACRLRTATIKSDTRLFTKLEMITELRLSSQASSTC 404          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV--KVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLS--IYLFENFKYLECCP-----------------PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            DRIS LPD +L  ILS +PTK +V T ILS RW+ ++ +V  LDF+ E   ++ +  +     GF  FV  VL L D+  I++FRL C         I  W+C   R     ++L +     V     LP+C+F C T+ V+K+    +      S   P LK L V  +V +   D + KL + CP LEDL + +T  D                            + + D+   +        K+ CL   + +F     + C                   P FD+L QL+ + +  Y WDLL  LL++S  LE   I  +  +       +W     VP CL+ HLKT  +R + G         Y+++N +VL  MT+
Sbjct:   20 DRISHLPDVLLLQILSLLPTKQAVITGILSKRWRPLWPAVSVLDFDDE---SSPEFHHPGGLTGFAEFVYSVLLLHDAPAIERFRLRCANPNYSARDIATWLCHVARRRAERVELSLSLSRYVA----LPRCLFHCDTVSVMKLNGVFLNALASFSVSLPLLKVLHVGDRVLFGCHDYVVKLLAGCPALEDLVLESTYND------------------ACGGVVCAEGNFQLDLKHLSSAKIGFSWKERCLKSMLLIFRALSNVRCLSLSTSTVACLKHASTSDIPVFDKLIQLE-ISFGNYSWDLLASLLQRSHKLEVLTIYKEPQKYAKGQEPRWIHPLLVPECLL-HLKTFCLREYQGLETELDFVGYIMQNARVLETMTI 376          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSL--DIQKFRLHC----YXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPED-DSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYLECCPPAFDQLTQLKLVLYDCY----RWDLLTQLLKKSPNLESXVI-ENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMT---------VXNDELYKELMLERGSRTC 1179
            DR+S LPD+V+CHILSF+PTK S  TSILS RW  ++ SV  LDF+         ++  + +  F  FV  V++LR+     IQ FRL C         D  R +  I    +  +  L+L +    +    F+LP CVF C  L  LK+K   I Y    +  FP LK L +  + +  D D   +L   CP+LEDL      +DLL+     +   +    + F+  Y +S                                         F  LT +K+V    +    +W  LT++L+  P L++  I E   D   ++D   W  T  VP C  S LKT ++ G+ G     + AKY+LKN KVL  MT         + +  L K  +  RGS TC
Sbjct:   11 DRVSVLPDSVICHILSFLPTKESAATSILSKRWNPLWLSVLTLDFD---------DQNFTEFSTFRHFVYSVIALRNITLQTIQSFRLKCGNSSGFNPHDVKRFIHAI---FQRGIQNLNLEMSPFKL---GFKLPHCVFSCSNLTALKLKGLAIDYSCDFN--FPLLKTLHLYTISFGRDRDCFLRLLKGCPILEDLE----TKDLLLHSSNSTGMYVSLFNVYFIQKYELS----------------------------------------TFLNLTHMKIVFELTHNWPGKWKWLTKVLQHCPKLQNLTIHEGSSDRNKIEDV-DWMDTPIVPECFSSQLKTCSLIGYKGMNCDFQFAKYILKNAKVLQTMTINASPVDINIKHQILIKLTLCPRGSTTC 351          

Query:   34 KDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLH----CYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLD-VKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENF-------------------------KYLECC----------PPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVL---------TKMTVXNDELYKELMLE-RGSRTC 1179
            +DR+S+LPD  L  ILS++PTK  + TS+LS RW+ ++  VP L+++      T        Y  F  FVDR L L  +  ++   +     CY   +D   +  W+   +   V EL++   S         LP+C+F C TL VLK++ N          CF S+K L  + V+Y +D S+ ++ S C  LEDL +     D  V +  ++AP LK L +   S      D  +   I+AP+L+ +DI+         EN                          K L  C             F QL  L+L       WDLLT+L + SP L    +  K           W+   S+P CL+ HL+T     + G    K+VA ++LK+   L         T   +   E+ KEL    RGS TC
Sbjct:    5 RDRLSQLPDDFLLQILSWLPTKDVMVTSLLSKRWRFLWTLVPRLNYDLRLHDNT--------YPRFSQFVDRSLLLHKAPTLESLNISIGSLCYTAEKD---VGVWVRIGVDRFVRELNISYCSGE---EPIRLPKCLFTCTTLAVLKLE-NISLVDASCYVCFQSVKTLHLLDVKYLDDQSLPRIISSCSSLEDLVVQRCPGD-NVKVVSITAPCLKTLSLHKSSQAFEGDDDGF--LIDAPRLKRVDIEDYWGGFCYIENMPEVVEANVDVIYKNTEKLLGSLTSVKRLALCLITSDAAYPTGTVFSQLVHLELCTCAPRWWDLLTRLFEDSPKLRVLKLRQKHIRRAPSPRACWKQPVSLPKCLLFHLETFKWELYEGSQKQKEVATFILKHAIRLKTAIISPKPTSTLLEKHEMLKELSSSPRGSSTC 418          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRD-SLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDLSIN-ATVRDLLVLMFKVSA--PELKRLRMTFVSAYLVSKDHEYDISIN-APKLENLDIKQDCLSIYLFENFKYLECCPPAFDQLTQLKL-----VLYDCYRWDLLTQLLKKSPNLESXVIENKED-EECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            DRIS+LPD++LCHIL F+PTK +  TS+LS RWK ++ SV   DF+  +  T+           FL  V   +  RD +L I  F  H   R  D  + V      +    + L+LC+    I     ELP  +    TL VLK+++  +          PSLK L + +V++   + + K+   CP+LEDL      V D         A  P L + R+T           E+ I ++   K + L I+     + +F N K+L    P F+ LT LKL     V Y  ++W  L ++LK SP L++ +I++ ED EE + +   W+   ++P CL S LKT  IR F G  +  + A Y+++N KVL  M +
Sbjct:   18 DRISDLPDSILCHILYFLPTKLAATTSVLSKRWKLLWLSVLAFDFDSSRFKTSDL---------FLRVVYSTIYRRDIALPIHSF--HLKSRSWDIQKDVNQFVYLVGQRGI-LNLCLDLSKICRYIIELPTTILSSGTLKVLKLRNLIVGDNSQVDLHLPSLKTLHLNRVDFECHEHLMKILLSCPILEDLETKLCCVMDFQSRFSDEFAAFPNLIKARIT-----------EFYIPLSMVCKAKTLHIE-----VPMFTNCKHL----PMFESLTYLKLSLSFKVWYPKWKW--LMRMLKLSPKLQNLIIKDNEDLEEKIDEC--WKDPPNIPECLSSQLKTCRIRVFKGTQYDLQFAIYIMENSKVLETMRI 356          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQ-KFRLHCYXRXEDFSRIVGWICTAIRHNVV---ELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDL-----------SINATVRDLLVLMFKVS-----------APELKRLRMTFVSAYLVSKDHE--------YDISINAPKLENLDIKQDCLSIYLFENF----KYLECC------------PPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPN---LESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXG-YPHVKKVAKYLLKNGKVLTKMTV---------XNDELYKELMLE-RGSRTCWV 1185
            D+ S+LPD +L  +LSF+PTK +VRTS+LS RWKS++  +P L+++F   S + + + ++ ++   +   +  ++ +SL ++ ++      + ED   I  W+  A+  + V    L LC +++       +LP+ ++ CK++V+LK+K   I   +P   C PSLK L + +V Y ++DS+ +L S CPVLEDL            ++  V+ L  L  K+S            P LK L++T       S +          YD   + PKLE  D      +I  F  F    K L  C               F+QL QLK+   D     LL++LL+ SPN   LE+ VIE+  D               VP CL+S L+T       G   +   VAKY+L+N + L   T+           DE+ +EL L  +G  TC V
Sbjct:    2 DKTSQLPDELLVKVLSFLPTKDAVRTSLLSMRWKSLWMWLPKLEYDFRHYSVS-EGQGLARFITLSLLGHKAPAI-ESLSLKLRYGAIGSIKPED---IYLWVSLAVHDSNVRELSLKLCTFAER----PTKLPKSLYKCKSIVILKLKDE-ILVDVPRKVCLPSLKTLFLGRVTYSDEDSLHRLLSNCPVLEDLVVERDRIDNLGKLSVVVKSLQRLTLKMSCPCHLDGIMMNTPSLKYLKVTDERQESDSDNESDSDSPRYFYDFE-DMPKLEEADFVLTFQNIKKFFKFVTSIKRLSLCLGVYTEESLYHEGLVFNQLEQLKICSCDSDWSILLSRLLESSPNLRELEAYVIEDHPDRRVDLPNQWGNQLNCVPKCLLSSLETFKWSEMYGLLQNQMDVAKYILRNARCLKSATIFFPTTYAKETRDEMIEELSLSFQGPETCQV 438          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCY---XRXEDFSRIVGWICTAIRHNVVELDLCVYS--DNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDLSINA----TVRDLLVLM------------------FKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCL----SIYLFENFKYLECCPP-------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYG----KWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND---------ELYKELMLERGSRTC 1179
            D+I+ LPD +L  ILS++PT  +V TSILS RW+ ++  +PNLD+     ++ W  +     VG   F+ + L L  +  I+  R H      + ED  R   WI  A+  +V +LD+  +S  +NI   +F      F CK+LV LK++S  +   +P+  C PSLK L +  V + E  S+++L S CPVLEDLS+        ++L +++                  + +  P L+ L++   +    S DH   +  N PKL    +   C      I    + K+L  C          F+QL  L L +       LL QLLK SPNL   ++E    E+ V D G     W    SVP CL+S L+      + G P  + +A Y+LKN + L K T+  D          + KEL+    +R C
Sbjct:    2 DKINGLPDDLLVKILSYVPTDIAVSTSILSKRWEFLWMWLPNLDY-----TSRWCRK--PGDVGLRDFIHKNLPLHRAPVIESLRFHSNSPDIKPEDIRR---WIEIAVSRHVHDLDIDHFSENENIFLSSF------FACKSLVTLKLRSVTLR-DIPSMVCLPSLKTLLLDNVSFVEGKSLQELLSICPVLEDLSVYCDDYENTKELTIVVPSLLSLSLYIPDEWLLDGYWIDTPSLEYLKLEDWN----SCDH-LSLIKNMPKLREAYVDAKCFLPKSVIESITSVKHLTICSKDGYGDGFVFNQLEHLTLCVCRGDSPSLLGQLLKDSPNLR--ILEISVMEDHVDDVGISLDGWNQPSSVPECLLSSLQIFKWPQYLGRPEDRDIAVYILKNARHLKKTTILADRCERFVTQRRMIKELLQALPARIC 410          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRL---HCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-------------TFVSAYLVSK-DHEYDISI-NAPKLEN-------LDIKQDCLSIYLFENFKYLECCPPA-------FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND-------ELYKELML-ERGSRTC 1179
            DRIS LPD VL  ILSF+PTK +V TSILS RW+ ++  +  L F  ++ S        S +     F+DR L L  +  I+ FRL     + + ED   I  W+  A+   + EL   +YS +       LP  ++ CK+LV+LK+    +   +P   C PSLK L++K V Y +  S+++L   CPVLEDL +N +  D +  +  V  P L+RL +             + +S  LV + D+ +   I N PKL          DIK    SI    + K L             F+ L +  L L++ Y  +LL   LK SPNL   ++ ++ D+        W     VP C++S L+  T   + G P  + +A Y+LKN   L   T+ +D       E+  EL L  + S TC
Sbjct:    2 DRISGLPDEVLVKILSFVPTKVAVSTSILSKRWEFLWMWLTKLKFGSKRYSE-------SEFKRLQCFLDRNLPLHRAPVIESFRLVLSDSHFKPED---IRMWVVVAVSRYIRELK--IYSSHYGEKQNILPSSLYTCKSLVILKLDGG-VLLDVPRMVCLPSLKTLELKGVRYFKQGSLQRLLCNCPVLEDLVVNLSHHDNMGKL-TVIVPSLQRLSLSTPSSREFVIDTPSLLSFQLVDRNDNSHTFLIENMPKLREAYINVPFADIKSLIGSI---TSVKRLAISSEVGYGEGFIFNHLEE--LTLWNKYSSNLLVWFLKNSPNLRELMLVSETDDHENLGMLSWNQPSIVPECMLSSLQKFTWFKYLGRPQDRDIAVYILKNACRLRTATIKSDTRLFTKLEMITELRLSSQASSTC 404          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRL---HCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-------------TFVSAYLVSK-DHEYDISI-NAPKLEN-------LDIKQDCLSIYLFENFKYLECCPPA-------FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXND-------ELYKELML-ERGSRTC 1179
            DRIS LPD VL  ILSF+PTK +V TSILS RW+ ++  +  L F  ++ S        S +     F+DR L L  +  I+ FRL     + + ED   I  W+  A+   + EL   +YS +       LP  ++ CK+LV+LK+    +   +P   C PSLK L++K V Y +  S+++L   CPVLEDL +N +  D +  +  V  P L+RL +             + +S  LV + D+ +   I N PKL          DIK    SI    + K L             F+ L +  L L++ Y  +LL   LK SPNL   ++ ++ D+        W     VP C++S L+  T   + G P  + +A Y+LKN   L   T+ +D       E+  EL L  + S TC
Sbjct:    2 DRISGLPDEVLVKILSFVPTKVAVSTSILSKRWEFLWMWLTKLKFGSKRYSE-------SEFKRLQCFLDRNLPLHRAPVIESFRLVLSDSHFKPED---IRMWVVVAVSRYIRELK--IYSSHYGEKQNILPSSLYTCKSLVILKLDGG-VLLDVPRMVCLPSLKTLELKGVRYFKQGSLQRLLCNCPVLEDLVVNLSHHDNMGKL-TVIVPSLQRLSLSTPSSREFVIDTPSLLSFQLVDRNDNSHTFLIENMPKLREAYINVPFADIKSLIGSI---TSVKRLAISSEVGYGEGFIFNHLEE--LTLWNKYSSNLLVWFLKNSPNLRELMLVSETDDHENLGMLSWNQPSIVPECMLSSLQKFTWFKYLGRPQDRDIAVYILKNACRLRTATIKSDTRLFTKLEMITELRLSSQASSTC 404          

Query:   31 GKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVS-APELKRLRMT-----------FVSA----YLVSKDHEYD-ISINAPKL------ENLDIKQDCLSIYLFENFKYLECCPP---------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDY------GKWRTTESVPICLISHLKTITIRGF-XGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            GKDRISELPDA+L  ILSF+PTK  V TS+ S +W+ ++  VPNL+F+ E      KE+Y  + +    F+     + +S     FRL       D   I  W+  A   ++ EL L V +D      F+ P  +  C TL  L++    I   + +     SL+ L ++ V Y ++ S+  L S CP+LE+L +     D  + +F +   P LKRL +             ++A    YL+ +D       +NAP+L      +   I  D    YL    + L    P          F QL  L++   +   WDLLT +L+ SP L+      K  + CVK +      GKW   + VP CL+SHL+T   R F  G    K++A Y+LKN + L K T   + +  E
Sbjct:   14 GKDRISELPDALLIKILSFLPTKIVVATSVFSKQWRPLWKLVPNLEFDSEDYDD--KEQYTFSEIVCKSFLSHKAPVLES-----FRLEFESEKVDPVDIGLWVGIAFSRHLRELVL-VAADTGTGTAFKFPSSLCTCNTLETLRLVL-LILVDISSPVVMKSLRTLHLELVSYKDESSIRNLLSGCPILEELLV-IRGEDSDIEVFTIDEVPSLKRLTINDDHDGQEFWGYVINAPSLKYLLIEDLRCPGFCLNAPELMEANIFDGTSITNDNFLGYLTSVKRLLLNLSPWKITYPTGSIFYQLVSLEMYTREIDWWDLLTLMLEHSPKLQVL----KLTDNCVKFHKNGLPGGKWNEPKYVPECLLSHLETFVWRRFDWGREEEKEIATYILKNARRLNKATFSTNPVNSE 412          

Query:   31 GKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRI-VG-WICTAIRHNVVELDLCVYSDNI-VCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM----------------TFVSAYLVSKDHEYDISINAPKLENLDIKQ-DCLSI-----------YLFENFKYLECCPPA---FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKD---YGKWRTTESVPICLISHLKTITIRGF-XGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            GKDRISELPD +L  ILS +PT   V TS+LS +W+S++  VPNL+F+         ++Y S +  F   V +      +  ++ FRL    +  +F+ + +G W+  A   ++ EL L  Y   +    TF  P  +  C TL  LK+   CI   +P+     SL+ L ++ V Y ++ S+  L S CP LE+L +     D  + +F +  P L+RL +                 F+   L+ +    +  +NAP+L   +I +   ++I            L  N   L+   P    F QL  L++   +   W+LLT +L+ SP L+   + ++  +   KD    GKW   + VP CL+S L+T   R F  G    K++A Y+LKNG+ L K T   + +  E
Sbjct:   19 GKDRISELPDGLLLKILSSLPTNIVVATSVLSKQWRSLWKLVPNLEFD--------SDDYESEHYTFSEIVCKSFLSHKAPVLESFRL----KFVNFNPVDIGLWVGIAFSRHLRELVLDFYPAELGKGVTFTFPSSLCTCNTLETLKLVL-CILVDIPSPVLMKSLRTLHLEFVRYKDESSVRNLLSGCPGLEELRLYRG-DDSDIKVFTIEVPSLQRLTIHDNNDGPEFWGYVINAPFLKYLLIEELRCPEFCLNAPELVEANIAEVTSITIEKFLGSFTSVSRLLLNLSPLKITYPTGSMFYQLVSLEMYTREAEWWNLLTLMLENSPKLQVLKLTDR-SQNFHKDGLVSGKWNEPKDVPECLLSQLETFVWRRFDWGREEEKEIATYILKNGRRLKKATFSTNPIESE 415          

Query:   31 GKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRI-VG-WICTAIRHNVVELDLCVYSDNI-VCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM----------------TFVSAYLVSKDHEYDISINAPKLENLDIKQ-DCLSI-----------YLFENFKYLECCPPA---FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKD---YGKWRTTESVPICLISHLKTITIRGF-XGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            GKDRISELPD +L  ILS +PT   V TS+LS +W+S++  VPNL+F+         ++Y S +  F   V +      +  ++ FRL    +  +F+ + +G W+  A   ++ EL L  Y   +    TF  P  +  C TL  LK+   CI   +P+     SL+ L ++ V Y ++ S+  L S CP LE+L +     D  + +F +  P L+RL +                 F+   L+ +    +  +NAP+L   +I +   ++I            L  N   L+   P    F QL  L++   +   W+LLT +L+ SP L+   + ++  +   KD    GKW   + VP CL+S L+T   R F  G    K++A Y+LKNG+ L K T   + +  E
Sbjct:   19 GKDRISELPDGLLLKILSSLPTNIVVATSVLSKQWRSLWKLVPNLEFD--------SDDYESEHYTFSEIVCKSFLSHKAPVLESFRL----KFVNFNPVDIGLWVGIAFSRHLRELVLDFYPAELGKGVTFTFPSSLCTCNTLETLKLVL-CILVDIPSPVLMKSLRTLHLEFVRYKDESSVRNLLSGCPGLEELRLYRG-DDSDIKVFTIEVPSLQRLTIHDNNDGPEFWGYVINAPFLKYLLIEELRCPEFCLNAPELVEANIAEVTSITIEKFLGSFTSVSRLLLNLSPLKITYPTGSMFYQLVSLEMYTREAEWWNLLTLMLENSPKLQVLKLTDR-SQNFHKDGLVSGKWNEPKDVPECLLSQLETFVWRRFDWGREEEKEIATYILKNGRRLKKATFSTNPIESE 415          

Query:    1 MCSKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTF-ELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM-------------TFVSAYLVSKDH--------------EYDISIN---APKLENLDIKQDCLSIY------------LFENFKYLECCP-PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRG-FXGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKE 1149
            +C K +SQ   ++R+S+LPD ++C ILS + TK +VRTSILSTRW++++  VP LDF+  +         + ++  F+ F      L     IQK R+  Y    ++  +  WI    RH +  +D+ V++    C  F  +P  ++ C TLV LK+    +T         P LK LD+  V +  + +++K+ SC PVLE+L+I  +  D  V + +V +  LKR+ +             T +  +L  K H              + DI +N      L N  + +D  +              + + F Y+E  P   F  L++L  V       ++L  LLK  P LES  ++  + E+  K+  +  ++   P CL+S LK + +     G     KVA+Y L+N  +L K+T+  D +YK+
Sbjct:    6 ICGKGSSQGSEEERLSQLPDHLICVILSHLSTKDAVRTSILSTRWRNLWQLVPVLDFDSRE---------LRSFSEFVSFAGSFFYLHKDSYIQKLRVCIYDLAGNY-YLTSWIDLVTRHRIQHIDISVFT----CSGFGVIPLSLYTCDTLVHLKLSR--VTMVNVEFVSLPCLKILDLDFVNFTNETTLDKIISCSPVLEELTIVKSSED-NVKIIQVRSQTLKRVEIHRRFDRHNGLVIDTPLLQFLSIKAHSIKSIEFINLGFTTKVDIDVNLLDPNDLSNRSMTRDFFTTISRVRSLVIRHGTIKDIFHYMELEPLQQFCYLSELSAVC-SISNLEMLLNLLKSCPKLESLSLKLVDYEKNKKE--EVMSSTVPPPCLVSSLKFVKLESQLLGCGTELKVARYFLENSTILEKLTLKIDYMYKD 414          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIR-HNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDL-----------SINATVRDLLVLMFKVSAP-ELKRLRMTFVS-AYLVSKDHE-----------------YDISINAPKLENLD-------IKQD------------CLSIYLFENFKYLECCPPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPN---LESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXG-YPHVKKVAKYLLKNGKVLTKMTV---------XNDELYKELMLE-RGSRTCWV 1185
            D+IS+LPD +L  +LSF+ TK +V TSILS RWKS++  +P L++ F   S + + + ++ ++   + V +  ++ +SL + KFR       +    I  W+  A+   NV EL L ++  N      +LP+ +  CK++V+LK+K   I   +P   C PSLK L + +V Y + +S+ +L S CPVLEDL            ++  V+ L  L  K+S P  L  L+M   S  YL   D                   YD   + PKLE  D       IK+             CL +Y  E+  +       F+QL QLK+   D     LL +LLK SPN   LE+ VIE+  +               VP CL+S L+T       G   +   VAKY+LKN + L   T+           DE+ +EL L  +G  TC V
Sbjct:   53 DKISQLPDELLVKVLSFLSTKDAVSTSILSMRWKSLWMWLPKLEYNFRHYSVS-EGQGLARFITSSLRVHKAPAI-ESLSL-KFRYGAIGSIKP-KDIYLWVSLAVHVSNVRELSLKLF--NFAELPTKLPKSLCKCKSIVILKLKDE-ILVDVPRKVCLPSLKTLFLGRVTYSDANSLHRLLSNCPVLEDLVMERDKIDNLGKLSVIVKSLQRLTLKMSRPCHLDGLKMNSPSLKYLKVIDERLESDSDDESDSDSPRYFYDFE-DMPKLEEADFVLTFQNIKKFFGSITSVKRLSLCLGVYTEESLYHEGL---VFNQLEQLKICSCDSDWSILLARLLKSSPNLRELEAYVIEDHPNGRTDLPNQWDNQLNCVPTCLLSSLETFRWSEMHGLLQNQMDVAKYILKNARCLKSATIFFPTTYAQETRDEMIEELSLSFQGPETCQV 489          

Query:   34 KDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLH----CYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLD-VKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENF-------------------------KYLECC-------PPA---FDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVL---------TKMTVXNDELYKELMLE-RGSRTC 1179
            +DR+S+LPD  L  ILS++PTK  + TS+LS RW+ ++  VP L+++      T           F  FVDR L L  +  ++   +     C+   +D   +  W+   +   V EL +   S         LP+C+F C TL VLK++ N          CF SLK L  + V+Y +D S+ ++ S C  LEDL +     D  V +  V+AP LK L +   S      D  +   I+ PKL+ +DI+         EN                          K L  C        PA   F QL  L+L       WDLLT+L++ SP L    +  K           W+   ++P CL+ HL+T     + G    K+VA ++LK+   L         T   +   E+ K+L    RGS TC
Sbjct:    5 RDRLSQLPDDFLLQILSWLPTKDVLVTSLLSKRWRFLWTLVPRLNYDLRLHDNTCPR--------FSQFVDRSLLLHKAPTLESLNIKIGSICFTAEKD---VGVWVRIGVDRFVRELSVSYCSGE---EPIRLPKCLFTCSTLAVLKLE-NITLEDASCYVCFQSLKTLHLLDVKYLDDQSLPRIISSCSSLEDLVVQRCPGD-NVKVVTVTAPSLKTLSLHKSSQAFEGDDDGF--LIDTPKLKRVDIEDYWGGFCYIENMPEVVEANVDVIYKNTEKLLGSITSVKRLALCLITSDAAYPAGTIFSQLVHLELCTCAPRWWDLLTRLIEDSPKLRVLKLRQKHIRRAPSPRASWK-QPALPKCLLFHLETFKWELYEGSQKQKEVATFILKHAIRLKTAIISPKPTSTLLEKHEMLKDLSSSPRGSSTC 417          

Query:   34 KDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLD--IQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDD--SMEKLFSCCPVLED-------------LSINATVRDLLVLMFKVSA---------------PELKRLRMTFV----------------SAYLVSKDHEYDISIN----------APKLENLDIKQDC--------LSIYLFENFKYLECCP--PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            KD IS+LP+ ++ HILSF+PTK ++ T ILS  W+ ++ S+ N DF+      TWK + +     F  F+DR   L +S +  I KFRL         SR+  WI  AI+ N+ EL L +Y+ + V     LP+ +F C+ LV+L +        L     FP LK L ++     DD  S+EKL +  PVLE+             L I ++    L++ F   A               P L+ L++T +                +A  V+  H + I ++           P +  + I + C        L        K L C    P F  LT+L++      RW +L ++LK SP LE  ++     E+  +    WR  E VP CL S LK I   GF       ++A+YL+KN  VL KMT+
Sbjct:   15 KDMISDLPNVIIGHILSFLPTKDALCTCILSKSWRELWRSLSNFDFD----DRTWKSKII-----FGNFMDRFCYLHNSRENSITKFRLRVNGSYPS-SRMSAWISAAIKDNLEELKLWIYTADHV----PLPRRIFSCEKLVILDLGYRIDIDLLGVGVHFPCLKVLHLQELPMLDDHASIEKLLAGSPVLEELKIEHEDCESRNVLRICSSSLKRLIIRFPFVAYDENDPGCRELTLDTPNLELLKLTDLVSEKLNMLQIPYSLVEAALSVAYKHVFTIQVDDYIDMAVQLLRPIMTIVKILRLCDTTMRTSPLQTLSDAVHKKLPCVGNLPDFQNLTRLEIEASGNDRWLVLHEILKCSPKLEVFILYKDSTEKTPR----WRNPEFVPRCLRSSLKVIEYVGFESELGEIEMAEYLIKNALVLEKMTI 428          

Query:   10 KSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCV-YSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSIN-ATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYLECCPPAFDQLTQLKLVLYDCYRWD----------LLTQLLKKSPNLESXVIENKEDEE----CVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            K +    G   I++LPDA+L HILSF+ TK +VRTSILS +W+ ++ S+ NL  EF Q     K +       F+  V+RVL LRDS +I+KF L C    +D +R   W+  A+  NV E  LCV + +     +F  P C+F C TL  LK+ S+ +   L +S   P LK L ++ V +P++DS +++ +    LE L I     ++L  +   +S+P+L+ L         + + H  D  +      ++ I    L+ + F    + + C      L +    +Y+CY             ++     K   L   V+E +  EE    C KD   W   E VP C  S LK I IR F G          LLKN   L  M +
Sbjct:    8 KQDMDDSGGKSINDLPDALLQHILSFLETKDAVRTSILSRKWEHLWKSLSNL--EFHQCYFKAKRKI------FMNSVERVLLLRDSSNIEKFTLSC--GIDDATRTRTWVSAAVNRNVKE--LCVNFYEGEESESFVFPLCLFTCATLTKLKITSHGV-LRLSSSISLPCLKILSLQHVVFPDEDSTQQILN-LRTLEKLKIRYYDWKNLKAI--TISSPKLRSLD--------ICEMHRND--LRGSDACHVMIFGTALTFFSFSGGFWDDYCLFKSSSLVEAYFDVYECYERSREIAHRAYKHIVGLSTVKHLTLTPDVLEIELSEELPTNCAKD--DW-ILEPVPPCFQSCLKCIEIRDFVGLIDELDAVALLLKNAIALDDMVI 367          

Query:   31 GKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDV-KVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLS 786
            G+  I  LPDA+L HILSF+ T+ +VRTSILS +W  ++ S  NL F F   S   K         F+ FVDRVL+LR   +I++F L C  + +D SR+  WI  A+  NV +L L +        +F LP C+F C+TL  L++    I   LP+S     LK L++ +V + +D S ++LFS  P L +L I+      LV                              +SI+APKL++LDI + C S
Sbjct:   24 GEKSIGNLPDALLEHILSFLLTEAAVRTSILSKKWLHLWKSTTNLTF-FGLKSPKRKL--------FMDFVDRVLALRGPSNIEQFYLSCEVK-DDPSRVGTWISAAVNRNVKDLYLELRDFE---ASFVLPHCLFNCETLTELEINMPYI-LKLPSSISLSCLKILNLYEVIFTDDHSTQQLFS-LPNLVELEIHECNWMNLVA-----------------------------VSISAPKLQSLDIHEPCQS 232          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMS---TTWKEEYMSNYVGFLMFVDRVLSLRD---SLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVK----------SNCITYGLP----------------------TSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSI------------NATVRDLLV----------LMFKVSAPELKRLRMTF----VSAYLVSKDHEYDISINAPKL-ENLDIKQ-------------------DCLSIYLFENFKYLECCPPAFDQLTQLKL-VLYDCYRWDLLTQLLKKSPNLESXVIE------------NKE--DEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV 1125
            DRIS+LPDA+L HIL  +P K   +TS+LS RW+S++ S P+LDF     S    + ++     +   + F+  VL+LRD    L   +FR H       FS + G I  AIR NV ELD+ V + +     F  P+ V   ++L VLK++          S+ +T G P                      T   FP LK L++   +     M+ L  CC  LEDL+I            +A + +L V            FKV+AP L+ +   +     S+ LV+    ++ S+    L ENL +++                   D   + +  N   +      F+ L  L+L   ++      L  L + SP L + +++            N++  D     +   W +        + HLK + I GF    +   +AK+LLK+GK L +MT+
Sbjct:   24 DRISDLPDAILHHILLLLPLKSIAQTSVLSQRWRSLWSSFPDLDFTTMNPSKAICSTRKLKSKRWWPSMDFIANVLALRDKHSDLRALRFRAHL-----SFSHLNGLIRRAIRCNVQELDVEVATGDY----FNFPRGVITSESLRVLKLRSRYPGFRLLPSSVMTIGFPSLHTLSLSLVILYEQSSLLDLFTESSFPCLKNLNLDACF----GMKHLKVCCRALEDLTIENCFQLHSLDICSAKLENLRVASCFDAYSDKTWFKVNAPRLRGISWEYNSITASSSLVNLTSLHEASVGFSLLHENLSVEKLQSVCNFLSGLSHVHSLTLDSQCVEILSNKNDIINLLHPFNNLKVLELHTGFEKNNVPGLAFLFRSSPTLHTLILKIINDFKTERRQWNRDLWDLSTSAEEQYWESQLQALRPFLDHLKVVKIHGFLECENEVSLAKFLLKHGKDLQEMTL 472          

Query:   34 KDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLD--IQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPE-----DD--SMEKLFSCCPVLEDLSIN---ATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHE-YDISINAPKLENLDIKQDCLSIYLFENFKYLEC 822
            KD IS LP+ ++ HILSF+PTK ++ T ILS  W+ ++ S+PN DF+         +    + + F  F+DR   + +S +  I KFRL  +      SR+  WI  AI+ N+ EL L +     +     LP+ VF C+ LVVL      ++YG+        ++F  +KV + E     DD  S+EKL +  PVLE+L I       R+ L    +V +  LKRL + F       KD     ++++ P LE L I  D +S  L  N + L C
Sbjct:   15 KDMISSLPNVIIGHILSFLPTKDALCTCILSKSWRELWRSLPNFDFD---------DRTSKSKIIFGNFMDRFFYVHNSRENSITKFRLRVHGNYPS-SRLSQWIDAAIKDNIEELILWI----PLLTHVPLPRRVFSCEKLVVLN-----LSYGIAIDLLGVGVRFSCLKVLHLEGLPMLDDLASIEKLLAGSPVLEELKIEHEYCQSRNAL----RVCSSSLKRLTIRFTRIRYYRKDPGCRALTLDTPNLELL-ILTDFVSEEL--NMQQLPC 264          

Query:   16 NSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDL-CVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVK-VEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYLECCPPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVI 939
            N+  +  + I  LPDA+L HILSF+P K +++TSILS RW+ ++ SV NL FE       W+ +    +V F+   +R +  RD   I+KF L  +    + + I   I  A+   V +  L  VY    V     LP  +F C TL VL ++        P + C P+LK + +     P   S+ + FS CP L+ L +N        L F +S P  + + +T +S+           +   P L+ L++   CL  Y     ++   CP         KL L +C +W L   L   +P LES VI
Sbjct:   20 NNMDEEINMIENLPDAMLLHILSFLPAKDALKTSILSKRWRHLWMSVSNLYFE------EWRPD---KFVMFMNSAERAMMCRDVPRIEKFSLSSHML--NSACINALISNALSFKVQDFSLRLVY----VGVPILLPHHLFSCPTLTVLNLEE---VTQFPCTACLPNLKKVRLSCCLLPHQQSLLQFFSGCPKLQKLILNRCFWRDANLGF-ISTPMPEPVDITQLSS-----------TTCLPDLKELEL-SFCLLPYGQSMVQFFGDCPKL------QKLTLKEC-QWGLAKCLYISTPMLESLVI 291          

Query:   10 KSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYV-GFLMFVDRVLSLRDSLDIQKFRLHCYXRXE-DFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM 684
            K +S    +DRIS LP+ +L HILSF+     V+T +LS RW +++ S P LDF FE  S+     Y  + +  F  F+  VL  R+  +++ F+L    R +  +S +   I  A++H+V E+ +     ++      LP+C F C++L  LK+K +     LP S    SLK L +      D    K+FS CP LE+L+I     + ++  F + A  LK L +
Sbjct:    7 KRSSLNNNEDRISTLPNVLLHHILSFLDAVQVVQTCVLSKRWMNVWKSHPYLDFNFETFSSLISSYYYDDDMNNFTDFISHVLVRRN--NVKAFKLSLDTRRDCQYSVVESLIYYAVKHHVEEISINTAHWDV---PIVLPRCFFDCESLRSLKLKVDG-GLALPKSLGLQSLKTLHLGGAQNFDG---KIFSSCPNLENLTIEDICLN-VIENFNIHALSLKSLEI 223          

Query:   10 KSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYV-GFLMFVDRVLSLRDSLDIQKFRLHCYXRXE-DFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRM 684
            K +S    +DRIS LP+ +L HILSF+     V+T +LS RW +++ S P LDF FE  S+     Y  + +  F  F+  VL  R+  +++ F+L    R +  +S +   I  A++H+V E+ +     ++      LP+C F C++L  LK+K +     LP S    SLK L +      D    K+FS CP LE+L+I     + ++  F + A  LK L +
Sbjct:    7 KRSSLNNNEDRISTLPNVLLHHILSFLDAVQVVQTCVLSKRWMNVWKSHPYLDFNFETFSSLISSYYYDDDMNNFTDFISHVLVRRN--NVKAFKLSLDTRRDCQYSVVESLIYYAVKHHVEEISINTAHWDV---PIVLPRCFFDCESLRSLKLKVDG-GLALPKSLGLQSLKTLHLGGAQNFDG---KIFSSCPNLENLTIEDICLN-VIENFNIHALSLKSLEI 223          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRL-HC-YXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDI----------KQDCLSIYLFENFKYLECCPPAFD-QLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKEDEECVK-------DYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMT---VXND---ELYKELM 1155
            DRIS LP  VL  ILS +P + +VRTS L  +W+  +  +P++ F+ + +S +  ++  +     +  +D +L L +   I KF+L HC      D  R   WI    R +  E  L ++        ++LP C+F  K LV L++  NC+         F +LK LD++      +  EKL S C +LE L+                               L++ D    ++INAP L+  D+              L++YL       +   P  D     ++L   D         LL+  PNL+   I  + +E+ V        D   W+       CL   L+ + I G  G        K+LL N  VL KMT   V N+   EL K+L+
Sbjct:    4 DRISSLPGHVLGQILSLLPIRDAVRTSALKRKWRYKWSQIPHIVFDSQGISIS-SQDQTTIKNKLVNIIDHILLLHNG-PIYKFKLSHCDLLAVSDIDR---WILHLSRGSAKEFVLEIWKGQ----QYKLPSCLFSFKNLVYLEL-FNCLLKPPLAFKGFRNLKNLDLQHVTLAQEVFEKLISSCAMLERLT-------------------------------LINFDGFTHLNINAPNLQFFDVGGVFDDVSFENTFVLALYLAIGKVPSKLPKPCIDLNYLSIRLNFNDYEENSAAFCLLRSCPNLQEIEILARPEEQAVVGPVTDFWDDDHWK-------CLFGQLRLVKIVGISGIRSELDCIKFLLSNSPVLEKMTIKPVSNEGGWELVKQLL 354          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEF---------EQMSTTWKEEYMSNYVGFLMFVDRVL--SLRDSLDIQKFRLH-CYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIV--CXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFP--SLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLEN 759
            D IS  PD VL HILSF+PTK  +RTSILS RWK +  + P LDF +            S    +EY      F+ +VD  +    +    +QKF+L       E  S +  W+   I +   E+D  +     +     + +P  +F  K++ VLK+        L  S C    SL+ L +K    +D  + ++ +CCP++ED+S+          + K+   EL RL+   + ++L   +    + I +P LE+
Sbjct:    2 DHISRFPDGVLHHILSFLPTKDVLRTSILSKRWKLVLDTYPILDFSWGDCAGQSSDAMYSENASDEYRQMLTKFMNYVDTSIFRFCKYKFSMQKFKLFLVLPDLELSSHLDKWVQKVIENGAKEVDFGIDLPGYLHFKKPYSMPDAIFAAKSVTVLKLFG--CNVKLEESFCIKLHSLQKLALKEVQMDDHLLRRIVTCCPLIEDISLR-----FCWGLKKIQVFELLRLKKFEIYSHLSKPE---SVEIKSPSLES 248          

Query:   10 KSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTW--KEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINA--TVRDLL----VLMFKVSAPELKRLRMTFV-SAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYLECCPPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENK---------EDEECV---KDYG------------------KWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV-------XNDELYKEL-MLERGSRTCWVELV 1194
            KSN  A+ +D+IS+LP+ VLCHILSF+PTKY+VRTSILSTRWK+++  VPNLDF++ +  + +  K++  S   GF  FVDRV+ LR S DI+KF LHC    +DF+ I GWI TAI+HNVVELDLC +        FELPQ +FMCKTLVVLK++SNCIT   P SGCFPSLK L V+VEYP +DSMEK+FSCCPVLEDL+I+   T+  LL    VL FK+SAPELK LR+      ++   DH+Y   IN PK+EN+D+KQD LS YLF+N K           L +  L L+     DL      ++  L + +   K         EDEEC+   ++Y                   KW T + VPICL+SHLKT++IRGF G+ H ++ AKYLL+NG+VL KMT+         +++YKE  M +RGSRTC VE +
Sbjct:   19 KSNPPARVEDKISKLPNEVLCHILSFLPTKYAVRTSILSTRWKNVWAFVPNLDFKYVEAKSYFFNKKKDKSTSAGFFTFVDRVICLRGSADIKKFCLHCSCGSKDFAGIDGWIRTAIQHNVVELDLC-FETTDKDLAFELPQFIFMCKTLVVLKLRSNCITNAPPASGCFPSLKILHVRVEYPVNDSMEKIFSCCPVLEDLTIDGLLTIDGLLGSDDVLNFKISAPELKTLRLILPHRKWVGDHDHQYCFLINCPKVENIDLKQDILSKYLFKNAK----------SLVKASLNLFSHAVADLQPDFSNRANALLAGISNVKYLSLSAHVWEDEECICSDEEYSEDGSSKEEYSEDGCSNAEKWNTPDFVPICLVSHLKTVSIRGFQGHLHEREAAKYLLENGEVLRKMTIYTGDFLPAKEKIYKEFSMFQRGSRTCQVEFI 449          

Query:   10 KSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTT--WKEEYMS-NYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTF-ELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYL----------------------ECCPPAFDQLTQLKL---VLYDCYR----WDLLTQLLKK-------------SPNLESXVIENKEDEECVKDYGK--------------WRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKELMLERGSRTCWVELV 1194
            K   Q   KDRISELPDA+LCHILSFIPTKY+VRTSILSTRWK I+ SVP LDFE++ +S    W E Y S +Y  FL FVDRVLS RD LDIQKFRLHCY   EDFSRI GWI T IRHNVVELDL V  +N       ELPQCVFMCKTL VLKVKSNCI Y  PTSGCFPSLKFL V V+YP++DSMEK+FSCCPVLE L+I+  +    VL F +S                               LE+LDIKQD LS Y FEN K L                            F  +  L L    L  C R    W++L+   K+             +    S  I   ++  C  DY K              WR  ESVP+CLISHLKTITIRG+ GYPH KKVAKYLLK G+VL++MT+ ND      M  R SR C +E +
Sbjct:   13 KPKRQDSVKDRISELPDAILCHILSFIPTKYAVRTSILSTRWKRIWASVPVLDFEYKALSVLFPWTEGYKSESYALFLTFVDRVLSSRDPLDIQKFRLHCYCSDEDFSRIDGWIRTVIRHNVVELDLHVEINNDEGGQIVELPQCVFMCKTLEVLKVKSNCIAYAPPTSGCFPSLKFLHVSVDYPDNDSMEKIFSCCPVLECLTIDGLLGFNDVLNFNIS-------------------------------LESLDIKQDILSKYSFENVKSLVKANVNLWCHYVNHQHAFSNRATALLGGFSNVKYLSLSAHFLASCSRDHLIWNILSWEHKEVRCTFTHAKSYQHASLYYSHFIHTLQNISCSGDYKKHENYSKHVLYSEHRWRKPESVPVCLISHLKTITIRGYKGYPHEKKVAKYLLKKGQVLSEMTICNDLSKDFAMSRRASRACQLEFI 436          

Query:   10 KSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMS-NYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYS--DNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYL 816
            KS  +   KD+ISELPD++LCH+LSFIPT+Y+VRTSILSTRWK I+ SVPNLDFE+   S    +EY S +Y GF  FVDRVLS RD LDI+K RLHC  R EDFSRI GWI T IRHNVVELDL V    D  +    ELPQCVFMCKTLVVLKV SNCITY  PTSGCFPSLKFL V VEYP++DSMEK+FSCCPVLE L+IN  +    VL F +S PEL+RLR+      + + D ++   +N PKLE+LDIKQD LS YLFEN K L
Sbjct:   13 KSKREEIVKDKISELPDSILCHMLSFIPTEYAVRTSILSTRWKRIWASVPNLDFEYRDDSVLLADEYDSESYAGFFTFVDRVLSCRDPLDIKKCRLHCDCRKEDFSRIDGWIRTVIRHNVVELDLNVKIGLDEDIDQPLELPQCVFMCKTLVVLKVNSNCITYTPPTSGCFPSLKFLHVSVEYPDNDSMEKIFSCCPVLECLTINGMLGLDDVLNFNISVPELRRLRLELKLDCVYNVDIKHTFFVNCPKLESLDIKQDILSNYLFENVKSL 284          

Query:    1 MCSKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISIN-----APKLENLDIKQDCLSIYLFENFKYLECCPPAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIENKE--------DEECVKDY--GKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTV-------XNDELYKEL-MLERGSRTCWVE 1188
            +  K   QA   DRISELPDAVLCHILSF+PTK +VRTSILSTRWK+I+ SV NLDF+ E       + ++     F MFVDRVLS R S DI KFRLHC    EDFSRI GWI TAI  N VE DL VYS +     FELPQ +FM KTLVVLK+ S+C+ Y  P SGCF                                                 P LK L +T         D+  D SI       P LE+L I               + C  PAFD L++LKLVL++C  W+LLT+LLK+SPNLE  V+E+ E        DEE   +Y   +W T E+VP+CL +HLK+ITIRGF G     + AKYLL+ GKVL K+T+         +EL +EL ++ RGSRTC VE
Sbjct:   10 LAKKPKPQAVVTDRISELPDAVLCHILSFLPTKLAVRTSILSTRWKNIWASVHNLDFDDEY------DPWIERDDSFSMFVDRVLSFRGSADIHKFRLHCSG-VEDFSRIDGWIRTAIDRNAVEFDLRVYSYSDF-QIFELPQSLFMSKTLVVLKLNSDCLRYVPPKSGCF-------------------------------------------------PSLKFLHVT--------GDYPDDESIEKLFYCCPVLEDLTIDG-------------VACSVPAFDNLSELKLVLHNCDNWELLTELLKRSPNLEYLVLEHNEVACTIYSDDEEYFAEYFDHEWNTPETVPVCLSAHLKSITIRGFKGDSDEMEAAKYLLEKGKVLNKVTIYAGDLLCSREELDEELELIRRGSRTCRVE 350          

Query:   34 KDRISELPDAVLCHILSFIPTK-YSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKV-KSNCITYGLPTSGCFPSLKFLDVKVEYPEDDS-MEKLFSCCPVLEDLSI---NATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQ----------DCLSI---------YLF-----------------ENFKYLECCP--------PAFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIEN--KEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXNDELYKEL-------MLERGSRTCWVE 1188
            KD ISELPDA+LC ILSF+PT  ++VRT+ILS RW +++  VPNLD +           +  ++  F MFVDRVL  RDS DI+KFRL       D +R+ GWICTA+R NVVEL+L +  D     TF LP+ VF CKTL VLK+  S CI Y  P S CFPSLK L V V  P   S ME +F+ CPVLEDLSI   N    D  +   KVSAPELK LRM+     L  K    ++ I+APKLE LD++           D  S+         Y F                  N KYL            P F  L +LK+V+Y C  WDLL  LL+ +PNLE   +E+    DE+  K +  W+  + VP CL+SHLKTIT+  F G     ++A+YLL NG +L K+T+     +  L          R S TC VE
Sbjct:    4 KDWISELPDALLCRILSFLPTTIWAVRTTILSKRWNNVWTCVPNLDLDCGGNFGY----HHCDHDRFAMFVDRVLCSRDSSDIKKFRLRTCVT--DLARVEGWICTAVRRNVVELELEL--DVGEKYTFVLPRSVFSCKTLKVLKLYGSLCIPYAPPASRCFPSLKCLLVSVRSPGCKSLMENVFTNCPVLEDLSISYTNLLENDAPIYKMKVSAPELKTLRMS-----LSEKYPGENVLIDAPKLEKLDVQTHLEGVSNYSLDARSLVNANIDFEDYYFADRASLPKHAIALLAGISNVKYLSLKTSYLRAGELPFFPNLNKLKVVVYRCKYWDLLAVLLENAPNLEDLDLEDGTMRDEKHSKLH--WKPPKVVPNCLMSHLKTITLCPFRGQKIDMELAEYLLNNGHLLDKITLYASYFWHTLDVRRALPKFNRASMTCQVE 432          

Query:    1 MCSKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVK--SNCITYGLPTSGCFPSLKFLDVKVEYPE-DDSMEKLFSCCPVLEDLSINAT---VRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFE-----------------------------------------NFKYLECCPP--------------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVI------ENKEDEECVKDYGKWRTTESVPICLISHLKTITIRGFXGYPHVKKVAKYLLKNGKVLTKMTVXN---------DELYKELMLERGSRTCWVE 1188
            MC K    A+ +DRIS LPDA++ HILSF+PT  +V T  LS RWK+++  VP +  E   +ST W         G   +VDR L  R S +I KF L C        RI GWICTA+R NVVEL L     +       LPQ +F+CKTL  LK+    +      PTS CFP LK L +  ++P+  + +EKLFSCCP LEDL ++     + +  VL   +SAP+LKRL++   +  +   +++  ++ + P LE+LD+ ++ L+ Y  +                                         N K+L    P               F+ L QL+L    C  W  LT +LK +PNLE+ +       +   DE+ ++   KW   E VP+CL S LKTI I GF G     ++ +YLL++G++L ++ +           + L + ++  R S TC ++
Sbjct:    1 MCPK----ARTEDRISALPDAIISHILSFLPTSDAVTTCFLSNRWKNMWTLVPTV--ELIVLSTAWDSG------GTAAYVDRYLLFRGSSNIHKFHLCCVDLDGIVGRINGWICTALRRNVVELHLEFDERDDSHEFLVLPQDLFVCKTLETLKLSLGEHVTAVAPPTSNCFPRLKSLHITFDFPKYVEQIEKLFSCCPALEDLVVDGDLGWLEENQVLNVTISAPKLKRLKIYLFAHAMTLGENKIFVNADVPSLEDLDLTENFLASYCLKGAKSLTNAKIDFSVMREEDEGHPADVLADVDRVQRLFAEISNVKHLSLVVPVLGDPHIEYQCSLPTFNHLNQLELNHLACCSWKSLTNMLKITPNLENLLFAVNIKCDAAHDEDELEH--KWSPPELVPVCLSSCLKTICISGFKGGSDEMEMVEYLLEHGQLLNELKILTFDMEFDDALEVLMEIILFPRASNTCEIQ 458          

Query:    1 MCSKSNS-QAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVK--SNCITYGLPTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYD----ISINAPKLENLDIKQDCLSIY------------------------------------LF---ENFKYLECCPP--------------AFDQLTQLKLVLYDCYRWDLLTQLLKKSPNLESXVIEN 945
            M S S S +A  +DRIS LPDA++ HILSF+ T+ +VRTS+LS RWK+ + SVPNL     +     +    S+  GF  FVDRVL  R S +I +FRL C    +DFSRI  WI TAI  NVVELDL +Y  +     F LP+ +FMCKTLV+LK++  SN I    P S CFPSLKFL V V  P+ DSMEKLFSCCP LEDL I        VL F+VSAP+LKRLR   +S Y+V     YD    I+ + P LE  +++++ L+ Y                                    LF    N K+L    P               F+ L  L+L+L +C     +T  L+ SP LE  V EN
Sbjct:    1 MGSNSKSREACHEDRISGLPDAIISHILSFLLTREAVRTSVLSHRWKNQWTSVPNLYLRDREYYPLERRLKKSDPDGFSGFVDRVLFFRGSSNIHRFRLLCL-EMKDFSRIDAWIRTAIMRNVVELDLELYEYSNPPHPFVLPRSLFMCKTLVLLKLRLQSNFIALA-PASDCFPSLKFLHVDVVLPDADSMEKLFSCCPALEDLVIEGEPGYDSVLNFEVSAPKLKRLR---ISWYIVPFHQNYDRKVFINADVPSLEEFNLQENILANYSLKNAHSLSRAKIDLVNLHSGEKFGTVRDSADHIQWLFAEIRNVKFLSLSAPVFGGPCSVYQYHLPTFNNLNHLELLLQNCCSLRSVTNFLQISPKLEHLVFEN 370          

Query:   40 RISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDF-----EFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLPTSGCFPSLKFLDVKVEYPE-DDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINA--PKLENLDIKQDCLSIYLFENFKYLECCPPAFDQL---TQLKLVLYDCYRWDLLTQLLKKSPNLESXV--IENKEDEECVKDYGKWRTTESVPICLISHLKTI 1035
            RIS LPD +L HILSF+PT  +VRT+ILS RW  ++ SVPN+D      EF+Q               F   VD VL  R +  I +FRLH     E    +  WICTAI HNVVELD+ +  D+     FELP+ ++MCKTLVV K+K   +    P S CFPSLKFL V V  P+  DSM K F+CCPVLEDL+I A      VL   +SAP+LKRLRM  V   ++ + ++Y   INA  P LE      + L+++  +N K L+     F+ L   +    +L+  +      + L  S  +   +  ++  + +E V +   W   ESVPICL SHLKT+
Sbjct:    1 RISGLPDEILYHILSFLPTVQAVRTTILSHRWNHVWASVPNIDLCDNIEEFDQER-------------FAGLVDHVLYSRGNSSIHRFRLHTKYMAE-LPWLDNWICTAITHNVVELDVDLARDSFSSEPFELPRSLYMCKTLVVSKLKLPSVITFAPHSDCFPSLKFLHVNVACPDAADSMGKRFTCCPVLEDLTIEAEPDGGSVLNVNISAPQLKRLRMN-VFLCIIGEYYDYKTFINANTPNLEKFSFDGNVLAVFSSKNAKSLKIAKNNFEGLHAGSDAAELLHRHFAGIGNVEYLGVSAPIFGHIKCLKQHDKDELVHE---WTPPESVPICLSSHLKTV 327          

Query:    7 SKSNSQAKGKDRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVELDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGLP-TSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDL-----LVLMFKVSAPELKRLRMTFVSAYLVSKDHEYDISINAPKLENLDIKQDCLSIYLFENFKYL 816
            SK +     +DRIS LPD VLCHILSF+ T  +V+T +LS RWK+++ SVPNL                S+      FVDRVLS R S  I +F L+ Y   + FS +  WICTAI  NVVEL L ++ +      +ELP  +FMCKTLV+LK+        +P  S CFP+LKFL V V +P+ DSM+KLFSCCP LEDL I+  V  +      VL   VSAP+LK L+++ + +++        I++NAP+LE LD+ ++  + Y  +N K L
Sbjct:    5 SKPHQACIDEDRISGLPDEVLCHILSFLYTITAVKTCVLSHRWKNLWASVPNLKLLICSPK--------SDSTCSPGFVDRVLSSRGSSRIHRFHLNLYGAHKYFSHVDEWICTAITRNVVELHLLLFPNP--WQRYELPSTLFMCKTLVILKLMLQFDIVAIPPNSDCFPNLKFLHVSVCFPDADSMKKLFSCCPALEDLIIDGNVEKIPGEADSVLRLNVSAPKLKILQISLMGSWM----RNVSITVNAPQLETLDLMENFFATYSLKNAKSL 266          

Query:   37 DRISELPDAVLCHILSFIPTKYSVRTSILSTRWKSIYGSVPNLDFEFEQMSTTWKEEYMSNYVGFLMFVDRVLSLRDSLDIQKFRLHCYXRXEDFSRIVGWICTAIRHNVVE----LDLCVYSDNIVCXTFELPQCVFMCKTLVVLKVKSNCITYGL-PTSGCFPSLKFLDVKVEYPEDDSMEKLFSCCPVLEDLSINATVRDLLVLMFKVSAPELKRLRMTFVSAYLVSKDH------EYD-----ISINAPKLENLDIKQDCLSIYLFENFKYL 816
            DRIS LPDA+L HILSF+ T+ +V+TS+LS RW  ++ SVP ++      +          +  F  FVD VL  R S +I  F+L C    EDF RI  WI TA+R NVVE    LD+ V S +     +ELP+ + MC TL VLK+  N     + P S CFPSLKFL V ++YP   S+EKL +CCPVLEDL I   ++D  V+   VSAP+LKRLRM  +S  LV  D       EY      I+ +AP LE  +++ + L+ Y   N K L
Sbjct:   18 DRISGLPDAILSHILSFLTTEDAVKTSVLSHRWFDVWTSVPKINLTLGSQAA---------FEPFAQFVDCVLFFRGSSNIHTFQLRCSVIEEDFCRIDPWIYTAVRRNVVEFEFDLDVDVDSKSHRYEGYELPRRLLMCNTLEVLKLTLNHKDIIINPPSDCFPSLKFLHVTLQYPGGHSLEKLLTCCPVLEDLIIEGHLKDDSVVNINVSAPKLKRLRMR-LSMDLVRWDEGDYKMLEYKCKRIYINADAPNLEEFNLRDNFLASYSLNNAKSL 283