MDP0000151393, MDP0000151393 (mRNA) Malus spp. (apple)

Query:    7 MAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESL-DESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYT 1995
            +AK  RA T  S + L +A++  +V+  FGSP    +DALLKFK  L   +    +++W+P   PC    +NWVGVLC NG++RGLQLE++ L G +DL+ LA LP  +TLS M+N  DGPLPD KK  KL++LYLS N FSG+IPD+ FEGM  L++LYLANN  +GKIPSSL TL ++ ++ LEGN+F GQIP+F QK +K +NV+ NELEGP+P++L ++ P +FAGN  LCGPP  G C P                     T  S G  KK S                     F+  + +K +S +  T S  +E+S    A+    +  +  ET+ H K+AD GKL+F+++D ++FDL DLL ASAE+LGSGTFG+SYKA+++   VVVKRY+ M+NVGREEFHEHMRRLGRL H NLLPL AYY RR+EKLLV++F E GSLASHLHGNH+ +   L W  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLDE+FEPLL DYAL PV+N E A   MMAYKSPEYAQ  R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL  WVN M+KEKRTSEVFD E+     S+GE++KLLKIG+SCCEEDVERRLD+ EVVEKI+ L EG+ D +      SEG+ Y+
Sbjct:    7 VAKFARATT--SSLVLVLAFVLSIVVTSFGSP---DSDALLKFKDQL---ANNGAINSWNPSVKPCEWERSNWVGVLCLNGSIRGLQLEHMALSGDIDLDALAPLPSFRTLSLMDNNFDGPLPDFKKLGKLKALYLSNNRFSGDIPDNAFEGMGSLKRLYLANNLLTGKIPSSLATLSKLMELKLEGNQFQGQIPNFQQKSMKTVNVASNELEGPIPEALSRLSPHSFAGNKGLCGPPL-GPCIPSPPS-----------------TPKSNG--KKFSILYIVIIILIVLLMLAAIAFAFLLFSRKKCKSRIQRTASSPEENSNKMVASYYRDVHRELSETSSHAKKADHGKLTFLKDDIEKFDLQDLLTASAEVLGSGTFGSSYKAVVVGQPVVVKRYRHMSNVGREEFHEHMRRLGRLKHPNLLPLAAYYNRRDEKLLVTEFAENGSLASHLHGNHSPEEDGLHWHIRLKIVKGVARGLAFLYNELP-IIAPHGHLKSSNVLLDESFEPLLTDYALRPVVNPEHAHMFMMAYKSPEYAQQSRTSNKTDIWSFGILILEMLTGKFPENYLTPCYNSDADLATWVNNMVKEKRTSEVFDKEIVGTKYSKGEMIKLLKIGLSCCEEDVERRLDIKEVVEKIDVLKEGDEDEEL---YGSEGNAYS 638          

Query:    7 MAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADY 1959
            +A L RA T +S + L +A++  +V+  FGSP    +DALLKFK+ L      E +SNW+   NPC  + +NWVGVLCFNG + GLQLE++GL G +DL+ LA LP  +TLS M+N  DGPLPD KK  KL++LYLS N FSG+IPD  FEGM  L++L+LANN  +GKI SSL  LP++ ++ L+GN+F GQIP+F QK +K  NV+ NELEGP+P++L ++ P++FAGN  LCGPP  G C P                   K  G      KK S                     F+  + ++ +       S  E+S    ++    +  +  ETN H +  D GKLSF+++D ++FDL DLLRASAE+LGSGT+G+SYKA++    VVVKRY+ MNNV REEFHEHMRR+GRL H NLLPL AYYYRR+EKLLV+ F E GSLASHLHGNH+ +   LDW  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLDE+FEPLL DYAL PVIN E A   MMAYKSPEYAQH R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL  WVN M+KEKRTSEVFD EM    NS+GE++KLLKIG+SCCE++VERR D+ EVV+KIEEL EG+ D D+
Sbjct:    5 VAMLARATT-SSLVLLVLAFVLSIVVTSFGSP---DSDALLKFKEQLV---NNEGISNWNVSVNPCERDRSNWVGVLCFNGGIWGLQLEHMGLAGNIDLDALAPLPSFRTLSLMDNNFDGPLPDFKKLGKLKALYLSNNRFSGDIPDKAFEGMGSLKRLFLANNLLTGKIASSLAILPKLTELKLDGNQFEGQIPNFQQKGMKTANVANNELEGPIPEALSRLSPNSFAGNKGLCGPPL-GPCIPSPPSTP-------------KAHG------KKFSILYIVIIILIVLLILAAIAFAFLLFSRKESKRRTQRRAS--ENSNRIMSSYYRDVHREMPETNSHSRITDHGKLSFLKDDIEKFDLQDLLRASAEVLGSGTYGSSYKAVVGGQPVVVKRYRHMNNVEREEFHEHMRRIGRLKHPNLLPLAAYYYRRDEKLLVTVFAENGSLASHLHGNHSLEEDGLDWRIRLKIVKGVARGLAFLYNQLP-IIAPHGHLKSSNVLLDESFEPLLTDYALRPVINPEHAHVFMMAYKSPEYAQHGRSSNKTDIWSFGILILEILTGKFPENYLTPGYNSDADLATWVNNMVKEKRTSEVFDKEMLGTKNSKGEMIKLLKIGLSCCEQEVERRSDIKEVVDKIEELKEGDDDEDF 625          

Query:   10 AKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGN-TANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTS 1998
            A L+RAPTP+    L +A +  +V +   S   S  D LLKF+  + LG+ T  L +W+  ++ C+ + T +W GV C+NG+V GL+LE LGL G +DL+ L+ L YL+T+SFMNN  +GPLP++KK   L+S+YLS NHFSG+IPDD F GM  L+K++LANN F+GKIPSSL TLPR+  + L+GNKF GQIPDF QK L  +N+S N L GP+P SL ++  S+F+GN  LCG P                              DSC +SKKPS                      + L+   +  +L G   +D  S  +  A SS ++  + E + H KRA+QGKL+FVR+DR+RFDL DLLRASAE+LGSG FG+SYKA++++ +A+V KRYKQMNNVGREEF EHMRRLGRL H NLLPLVAYYYR+EEKLLVS++VE GSLASHLHGNH+ D P L+WPTRLRIIKG+++GL YLY+ LPSL+V HGHLKSSNVLLDE+F P+L DYALLPVIN E A+ LM+AYKSPE+AQH R TKKTDVW  GI+ILE+LTGKFP NYL    +S+ + + WVN +  ++   EVFD EMG   NS+GE+LKLLKIG++CCEEDVERR DL E ++ IEEL       +     + EGD++ S
Sbjct:    6 ALLVRAPTPSP---LPIALILILVSIT-SSEAVSDADILLKFR--VSLGNAT-ALGDWNTSRSVCSTDQTESWNGVRCWNGSVWGLRLEGLGLNGAIDLDSLSSLRYLRTISFMNNSFEGPLPEIKKLVALKSVYLSNNHFSGDIPDDAFSGMAYLKKVHLANNKFTGKIPSSLATLPRLLVLRLDGNKFEGQIPDFQQKHLANVNISNNMLGGPIPASLSRISSSSFSGNKDLCGKPL-----------------------------DSC-SSKKPSAVIVALIVVAIALILVTIGLLLLVLHRNIRTVQLGGAAPVDNHSM-SEVAHSSLVECGTSEMSGHSKRAEQGKLTFVRDDRERFDLQDLLRASAEVLGSGNFGSSYKAVLLSGEAMVAKRYKQMNNVGREEFQEHMRRLGRLAHPNLLPLVAYYYRKEEKLLVSEYVENGSLASHLHGNHSIDQPGLNWPTRLRIIKGVAKGLAYLYNELPSLIVAHGHLKSSNVLLDESFNPVLTDYALLPVINPEHARQLMVAYKSPEFAQHSRTTKKTDVWGLGILILEILTGKFPTNYLTVGNNSE-EGITWVNSIANQEWMMEVFDKEMGGTENSKGEMLKLLKIGLACCEEDVERRWDLKEAIKHIEEL-------EVTDGTNDEGDEFPS 624          

Query:   40 SFITLFVAYLSCMVMLPFGSPMD-------STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN---------NRKQRSELDGTESL--DESSKYTAAAGSSQMDVKSVETNPHPKRA---DQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            +FIT F+  + C V +    P         S  D LL+FK TL   S    +S+WDP  +PC  N+ NW GVLC  GNV GLQLE +GL GKLDLEPLA +  L+TLSFMNN  +G +P +K F  L+SLYLS N F+GEIP D F+GMH L+KL LANNAF G IPSSL  LP + ++ L GN+F G+IP F QKDLK  +   N+LEGP+P+SL  MDP +F+GN  LCGPP                           C+ DS  +   PS                      + L          + ++R  L    S   D + KY     + +       T+   +R    DQ KL F+++D QRFDL DLLRASAE+LGSG+FG+SYK  I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H NLLP+VAYYYRREEKLL+++F+   SLASHLH NH+ D P LDWPTRL+II+G+++GL YL++ L +L +PHGHLKSSNV+LDE+FEPLL DYAL PV+N EQ+ +LM++YKSPEY+    +TKKTDVWC G++ILE+LTG+FPENYL Q YD+   LV WV+ M+KEK+T +VFD EM    N + E+L LLKIG+SCCEED ERR+++ + VEKIE L EGE D D+ S+
Sbjct:   21 AFITTFLIIVLCPVTMVMSQPQADVLPLPASDADCLLRFKDTLVNAS---FISSWDPSISPCKRNSENWFGVLCVTGNVWGLQLEGMGLTGKLDLEPLAAIKNLRTLSFMNNKFNGSMPSVKNFGALKSLYLSNNRFTGEIPADAFDGMHHLKKLLLANNAFRGSIPSSLAYLPMLLELRLNGNQFHGEIPYFKQKDLKLASFENNDLEGPIPESLSNMDPVSFSGNKNLCGPPLS------------------------PCSSDSGSSPDLPSSPTEKNKNQSFFIIAIVLIVIGIILMIISLVVCILHTRRRKSLSAYPSAGQDRTEKYNYDQSTDKDKAADSVTSYTSRRGAVPDQNKLLFLQDDIQRFDLQDLLRASAEVLGSGSFGSSYKTGINSGQMLVVKRYKHMNNVGRDEFHEHMRRLGRLKHPNLLPIVAYYYRREEKLLIAEFMPNRSLASHLHANHSVDQPGLDWPTRLKIIQGVAKGLGYLFNELTTLTIPHGHLKSSNVVLDESFEPLLTDYALRPVMNSEQSHNLMISYKSPEYSLKGHLTKKTDVWCLGVLILELLTGRFPENYLSQGYDANMSLVTWVSNMVKEKKTGDVFDKEMTGKKNCKAEMLNLLKIGLSCCEEDEERRMEMRDAVEKIERLKEGEFDNDFAST 658          

Query:  109 STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN---------NRKQRSELDGTESL--DESSKYTAAAGSSQMDVKSVETNPHPKRA---DQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSS 1977
            S  D LLKFK TL   S    +S+WDP  +PC  N+ NW GVLC  GNV GLQLE +GL GKLDLEPLA +  L+TLSFMNN  +G +P +K    L+SLYLS N F+GEIP D F+GMH L+KL LANNAF G IPSSL +LP + ++ + GN+F GQIPDF QKDLK  +   N+LEGP+P SL  MDP +F+GN  LCGPP                           C+ DS  +   PS                      + L          + ++R  L    S   D + KY     + +       T+   +R    DQ KL F+++D QRFDL DLLRASAE+LGSG+FGASYK  I +   +VVKRYK MNNVGREEFH+HMRRLGRL H NLLP+VAYYYRREEKLL+++F+   SLASHLH NH+ D P LDWPTR++II+G+++GL YL++ L +L +PHGHLKSSNV+LDE+FEPLL DYAL PV+N EQ+ +LM++YKSPEY+    +TKKTDVWC G++ILE+LTG+FPENYL Q YD+   LV WV+ M+KEK+T +VFD EM    N + E+L LLKIG+SCCEED ERR+++ + VEKIE L EGE D D+ S+ ++
Sbjct:   51 SDADCLLKFKDTLVNAS---FISSWDPSISPCKRNSENWFGVLCVTGNVWGLQLEGMGLTGKLDLEPLAPIKNLRTLSFMNNKFNGSMPSVKNLGALKSLYLSNNRFTGEIPADAFDGMHHLKKLLLANNAFRGNIPSSLASLPMLLELRVNGNQFHGQIPDFKQKDLKLASFENNDLEGPIPGSLSNMDPGSFSGNKNLCGPPLS------------------------PCSSDSGSSPDLPSSPTEKNKNQSFFTIAIVLIVIGIILMIISLVVCILDTRKRKSLSAYPSAGQDRTEKYNYDQSTDKDKAADSVTSYTSRRGAVPDQNKLLFLQDDIQRFDLQDLLRASAEVLGSGSFGASYKTGINSGQTLVVKRYKHMNNVGREEFHDHMRRLGRLNHPNLLPIVAYYYRREEKLLIAEFMPNRSLASHLHANHSVDQPGLDWPTRVKIIQGVAKGLGYLFNELTTLTIPHGHLKSSNVVLDESFEPLLTDYALRPVMNSEQSHNLMISYKSPEYSLKGHLTKKTDVWCLGVLILELLTGRFPENYLSQGYDANMSLVTWVSNMVKEKKTGDVFDKEMTGKKNCKAEMLNLLKIGLSCCEEDEERRMEMRDAVEKIERLKEGEFDNDFASTTNN 661          

Query:   46 ITLFVAYLSCMVMLPFGSPMDSTTD--ALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQR-SELDGTESLDESSK------YTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            +   V   S  V + FG   ++ TD  ALLKFK  L     +  L NW+P   PC  + +NW+GVLC NG++ GL+LE++ L G +D++ L  LP+ +TLS M+N LDGP PD+KK  KL++LYLS N FSG+IPDD F+GM  L+++++ANN F+G IP SL TLPR+ ++ LEGN+F G IPDF Q  LK +N++ N+L GP+P SL K+DP +F+GN +LCGPP                              D C + +  S                      + +  RK R S+L+ T SL  +S       Y       QM V+ +      +R+D  +LSFVRED ++FDL+DLLRASAE+LGSGTFG+SYKA + +  A+VVKRY+ MNNVGREEFHEHMRRLGRL H NLL L AYYYRREEKLLV ++VE GSLAS LH N++ +   LDW TRLR+IKG+++GL YLY  LP ++VPHGHLKSSNVLLD + EPLL DYAL PVIN +QA +LM+AYKSPEYAQ+ R + KTD+W FGI+ILE+LTGKFPENYL   YD+ ADL +WVN M+KEKRTSEVFD +M     S+GE++ +LKIG+SCCEEDVE R+D+ +VVEK+E+L EG+S+ +Y  S
Sbjct:   24 VVALVLASSSFVHMAFG---ENATDSVALLKFKDAL---GNSSALYNWNPIFPPCEWDRSNWIGVLCLNGSIWGLKLEHMSLAGSIDVDSLLPLPFFRTLSLMDNDLDGPFPDIKKLGKLKALYLSNNRFSGQIPDDAFQGMGSLKRVFMANNMFTGNIPLSLATLPRLMELRLEGNQFKGLIPDFQQHVLKTVNLASNQLVGPIPTSLSKLDPDSFSGNKELCGPPL-----------------------------DPCSSPENKSNVLKIIITVMVVLLIVAAVAFALAVLWRKSRGSQLERTSSLSANSNKIAPNTYVGDQEQIQMPVEQL------RRSD--RLSFVREDVEKFDLNDLLRASAEVLGSGTFGSSYKASVGSGVALVVKRYRHMNNVGREEFHEHMRRLGRLQHPNLLRLAAYYYRREEKLLVYEYVEHGSLASRLHSNNSLEGQGLDWHTRLRVIKGVAKGLAYLYGELP-ILVPHGHLKSSNVLLDPSLEPLLTDYALRPVINPQQAHNLMIAYKSPEYAQNGRTSNKTDIWSFGILILEILTGKFPENYLTAGYDTSADLASWVNKMVKEKRTSEVFDKDMKGAKYSKGEMINVLKIGLSCCEEDVESRVDIEQVVEKLEQLKEGDSEGEYYGS 630          

Query:   43 FITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQR-----SELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQG-KLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEY--AQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRS 1965
            FI +F++ L  + M     P DS  D LL+FK TL  GS+     +WDP  +PC GNTANW GVLC N  V GLQLE +GL GKL+L+PL  +  L+T+SFMNN  +GP+P +K+F  L+SLYLS N FSGEIP D F GM LL+K+ LANNAF G IPSSL +LP + ++ L GN+F GQIP F QKDLK  +   N+L+GP+P+SL+ MDP +FAGN  LC  P    C+                      TG   G     S                     F F+ +R++          G E + ES  Y  +   +    +SV         D G +L FVR+D QRFDL DLLRASAE+LGSGTFGASYKA I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H N+LPLVAYYYRREEKLLV++F+   SLASHLH N+++    LDW TRL+IIKG+++GL+YL+  LP+L +PHGH+KSSN++LD++FEPLL DYAL P+++ E A + M AYKSPEY  ++ + ITKKTDVWCFG++ILEVLTG+FPENYL Q YDS   LV WVN M+KEK+T +VFD EM    N + E++ LLKIG+ CCEE+ ERR+D+ EVVE +E L EGES+ D+ S
Sbjct:   25 FIIIFISVLCPVAMSQVVVP-DSDADCLLRFKDTLANGSE---FRSWDPLSSPCQGNTANWFGVLCSN-YVWGLQLEGMGLTGKLNLDPLVPMKNLRTISFMNNNFNGPMPQVKRFTSLKSLYLSNNRFSGEIPADAFLGMPLLKKILLANNAFRGTIPSSLASLPMLLELRLNGNQFQGQIPSFQQKDLKLASFENNDLDGPIPESLRNMDPGSFAGNKGLCDAPLS-PCSSSSPGVPVVPVSPVDPKSTSPPTGKKAG-----SFYTLAIILIVIGIILVIIALVFCFVQSRRRNFLSAYPSSAGKERI-ESYNYHQSTNKNNKPAESVNHTRRGSMPDPGGRLLFVRDDIQRFDLQDLLRASAEVLGSGTFGASYKAAISSGQTLVVKRYKHMNNVGRDEFHEHMRRLGRLNHPNILPLVAYYYRREEKLLVTEFMPNSSLASHLHANNSAG---LDWITRLKIIKGVAKGLSYLFDELPTLTIPHGHMKSSNIVLDDSFEPLLTDYALRPMMSSEHAHNFMTAYKSPEYRPSKGQIITKKTDVWCFGVLILEVLTGRFPENYLTQGYDSNMSLVTWVNDMVKEKKTGDVFDKEMKGKKNCKAEMINLLKIGLRCCEEEEERRMDMREVVEMVEMLREGESEDDFGS 659          

Query:   43 FITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLD----ESSKYTAAAGSSQMDVKSVETNPHPKRADQ----GKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEY--AQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRS 1965
            F+ +F++ L  + M     P DS  D LL+FK TL  GS+    ++WDP  +PC GNTANW GVLC N  V GLQLE +GL GKL+L+PL  +  L+T+SFMNN  +GP+P +K+F  L+SLYLS N FSGEIP D F GM LL+K+ LANNAF G IPSSL +LP + ++ L GN+F GQIP F QKDLK  +   N+L+GP+P+SL+ MDP +FAGN  LC  P    C+P                     TG   G     S                     F F+  R+ R+ L    S      ES  Y  +A  +    +SV    H +R       G+L FVR+D QRF L DLLRASAE+LGSGTFGASYKA I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H N+LPLVA     EEKLL++  +   SLA+HLH NH++    LDW TRL+IIKG+++GL+YL+  LP+L +PHGH+KSSN++LDE+FEPLL DYAL PV++ E A + M AYKSPEY  ++ + ITKKTDVWCFG++ILEVLTG+FPENYL Q YDS   LV WVN M+KEK+T +VFD EM    N + E++ LLK+G+ CCEE+ ERR+D+ EVVE IE L EGES+ D+ S
Sbjct:   25 FLIIFISVLCPVAMSQVVVP-DSDADCLLRFKDTLANGSE---FTSWDPLTSPCQGNTANWFGVLCSN-YVWGLQLEGMGLTGKLNLDPLVPMKNLRTISFMNNNFNGPMPQVKRFTSLKSLYLSNNRFSGEIPADAFRGMPLLKKILLANNAFRGTIPSSLASLPMLLELRLNGNQFQGQIPSFQQKDLKLASFENNDLDGPIPESLRNMDPGSFAGNKDLCDAPLS-PCSPSSPGVPVVPVSPVDPKSTSPSTGKKTG-----SFYTLAIILIVIGIILVIIALVFFFVQTRR-RNFLSAYPSAGKERIESYNYHQSASKNNKPAESVVN--HTRRGSMPDPGGRLLFVRDDIQRFGLQDLLRASAEVLGSGTFGASYKAAISSGQTLVVKRYKHMNNVGRDEFHEHMRRLGRLNHPNILPLVALLLP-EEKLLITQLMPNSSLANHLHANHSAG---LDWITRLKIIKGVAKGLSYLFDELPTLTIPHGHIKSSNIVLDESFEPLLTDYALRPVMSSEHAHNFMTAYKSPEYRPSKGQVITKKTDVWCFGVLILEVLTGRFPENYLTQGYDSNMSLVTWVNDMVKEKKTGDVFDKEMKGKKNCKAEMINLLKVGLRCCEEEEERRMDMREVVEMIEMLREGESEDDFGS 658          

Query:   52 LFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMD-VKSVETNPHP-KRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQV 2004
            +F+  +S + +        S ++ LL+FK +L+       L +W+    PC G+   WVGV+C NG+V GLQLE +GL G +D++ LA+LP+L+ +SFMNN  DG +P +KK   L+S++LS N FSGEI DD F GM  L+K++LA+N FSG +P SL  LPR+ ++ LEGN F GQIP+F    L+  N+S N LEGP+P+SL+KM+ ++F+GN  LCG P                               SC   KKP+                     F+ L   K ++ L   E+    SK T      ++D VK  E+N    K+ +QGKL ++R D  + DL DLL+ASAEILGSG FG+SYKA+++   +VVVKR++ MNNVG+EEF EHMRRLGRL H NLLP VAYYYR EEKLLV+DF++ GSLA HLHGNH  D P LDW TRL+IIKGI++GL YLY+ LP+L+ PH HLKSSNVLL ++F PLL DY L+P+IN E AQ LM+AYKSPEY QH RITKKTDVW FG +ILE+LTGKFP   L+Q   S  DL +WVN + +E+   EVFD EMG   NS+ E++KLLKIG++CCE DV +R D+ E VEKIEEL E +S+ D+ SS +SE +  + Q+
Sbjct:   11 IFLVIISVVHINVASGAKPSQSEILLEFKNSLR---NVTALGSWNTSTTPCGGSPGGWVGVICINGDVWGLQLEGMGLMGTIDMDTLAKLPHLRGISFMNNHFDGAIPKIKKLSALKSVFLSNNQFSGEIEDDAFSGMVSLKKVHLAHNKFSGGVPESLALLPRILELRLEGNHFKGQIPEFRATQLQSFNISNNNLEGPIPESLRKMELTSFSGNKNLCGAPL-----------------------------GSCPRPKKPTTLMMVVVGIVVALALSAIIVAFILLRCSKCQTTLVQVET--PPSKVTCR----ELDKVKLQESNTESGKKVEQGKLYYLRNDENKCDLKDLLKASAEILGSGYFGSSYKAVLVNGSSVVVKRFRHMNNVGKEEFQEHMRRLGRLNHPNLLPFVAYYYREEEKLLVTDFIDNGSLAIHLHGNHARDQPRLDWATRLKIIKGIAKGLAYLYTELPTLIAPHSHLKSSNVLLSKSFTPLLTDYGLVPLINQEIAQALMVAYKSPEYKQHGRITKKTDVWSFGTLILEILTGKFPTQNLQQGQASDTDLASWVNSVSQEEWEDEVFDKEMGGTTNSKWEMVKLLKIGLACCEGDVGKRWDMKEAVEKIEELKEKDSEDDFYSSYASEMESPSRQL 626          

Query:   52 LFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMD-VKSVETNPHP-KRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQV 2004
            +F+  +S + +        S ++ LL+FK +L+       L +W+    PC G+   WVGV+C NG+V GLQLE +GL G +D++ LA+LP+L+ +SFMNN  DG +P +KK   L+S++LS N FSGEI DD F GM  L+K++LA+N FSG +P SL  LPR+ ++ LEGN F GQIP+F    L+  N+S N LEGP+P+SL+KM+ ++F+GN  LCG P                               SC   KKP+                     F+ L   K ++ L   E+    SK T      ++D VK  E+N    K+ +QGKL ++R D  + DL DLL+ASAEILGSG FG+SYKA+++   +VVVKR++ MNNVG+EEF EHMRRLGRL H NLLP VAYYYR EEKLLV+DF++ GSLA HLHGNH  D P LDW TRL+IIKGI++GL YLY+ LP+L+ PH HLKSSNVLL  +F PLL DY L+P+IN E AQ LM+AYKSPEY QH RITKKTDVW FG +ILE+LTGKFP   L+Q   S  DL +WVN + +E+   EVFD EMG   NS+ E++KLLKIG++CCE DV +R D+ E VEKIEEL E +S+ D+ SS +SE +  + Q+
Sbjct:   11 IFLVIISVVHINVASGAKPSQSEILLEFKNSLR---NVTALGSWNTSTTPCGGSPGGWVGVICINGDVWGLQLEGMGLMGTIDMDTLAKLPHLRGISFMNNHFDGAIPKIKKLSALKSVFLSNNQFSGEIEDDAFSGMVSLKKVHLAHNKFSGGVPESLALLPRILELRLEGNHFKGQIPEFRATQLQSFNISNNNLEGPIPESLRKMELTSFSGNKNLCGAPL-----------------------------GSCPRPKKPTTLMMVVVGIVVALALSAIIVAFILLRCSKCQTTLVQVET--PPSKVTCR----ELDKVKLQESNTESGKKVEQGKLYYLRNDENKCDLKDLLKASAEILGSGYFGSSYKAVLVNGSSVVVKRFRHMNNVGKEEFQEHMRRLGRLNHPNLLPFVAYYYREEEKLLVTDFIDNGSLAIHLHGNHARDQPRLDWATRLKIIKGIAKGLAYLYTELPTLIAPHSHLKSSNVLLSXSFTPLLTDYGLVPLINQEIAQALMVAYKSPEYKQHGRITKKTDVWSFGTLILEILTGKFPTQNLQQGQASDTDLASWVNSVSQEEWEDEVFDKEMGGTTNSKWEMVKLLKIGLACCEGDVGKRWDMKEAVEKIEELKEXDSEDDFYSSYASEMESPSRQL 626          

Query:   52 LFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMD-VKSVETNPHP-KRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQV 2004
            +F+  +S + +        S ++ LL+FK +L+       L +W+    PC G+   WVGV+C NG+V GLQLE +GL G +D++ LA+LP+L+ +SFMNN  DG +P +KK   L+S++LS N FSGEI DD F GM  L+K++LA+N FSG +P SL  LPR+ ++ LEGN F GQIP+F    L+  N+S N LEGP+P+SL+KM+ ++F+GN  LCG P                               SC   KKP+                     F+ L   K ++ L   E+    SK T      ++D VK  E+N    K+ +QGKL ++R D  + DL DLL+ASAEILGSG FG+SYKA+++   +VVVKR++ MNNVG+EEF EHMRRLGRL H NLLP VAYYYR EEKLLV+DF++ GSLA HLHGNH  D P LDW TRL+IIKGI++GL YLY+ LP+L+ PH HLKSSNVLL ++F PLL DY L+P+IN E AQ LM+AYKSPEY QH RITKKTDVW FG +ILE+LTGKFP   L+Q   S  DL +WVN + +E+   EVFD EMG   NS+ E++KLLKIG++CCE DV +R D+ E VEKIEEL E +S+ D+ SS +SE +  + Q+
Sbjct:   11 IFLVIISVVHINVASGAKPSQSEILLEFKNSLR---NVTALGSWNTSTTPCGGSPGGWVGVICINGDVWGLQLEGMGLMGTIDMDTLAKLPHLRGISFMNNHFDGAIPKIKKLSALKSVFLSNNQFSGEIEDDAFSGMVSLKKVHLAHNKFSGGVPESLALLPRILELRLEGNHFKGQIPEFRATQLQSFNISNNNLEGPIPESLRKMELTSFSGNKNLCGAPL-----------------------------GSCPRPKKPTTLMMVVVGIVVALALSAIIVAFILLRCSKCQTTLVQVET--PPSKVTCR----ELDKVKLQESNTESGKKVEQGKLYYLRNDENKCDLKDLLKASAEILGSGYFGSSYKAVLVNGSSVVVKRFRHMNNVGKEEFQEHMRRLGRLNHPNLLPFVAYYYREEEKLLVTDFIDNGSLAIHLHGNHARDQPRLDWATRLKIIKGIAKGLAYLYTELPTLIAPHSHLKSSNVLLSKSFTPLLTDYGLVPLINQEIAQALMVAYKSPEYKQHGRITKKTDVWSFGTLILEILTGKFPTQNLQQGQASDTDLASWVNSVSQEEWEDEVFDKEMGGTTNSKWEMVKLLKIGLACCEGDVGKRWDMKEAVEKIEELKEKDSEDDFYSSYASEMESPSRQL 626          

Query:   58 VAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVE------TNPHPKRADQGKLSF------VREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELY 1935
            V + + +++ PF   M S ++ALLK K++    + T  L +W+P   PC+G+   W G++CFNG V GL L  +GL GK+D+E L  +  L+T+S +NN   G +P+  +   L+++++S N FSGEIP D F  M  L+KL+L++N F+G IP S+  L  + ++ LE N+F+G IPDF    LK LN+S N+L+G +P SL K   S FAGN  LCG      CN H                     G   GT +                         +FL  R++  E D  E++DES +    +GSS+ +  S        +     R+ Q K S       V E++  F + DL++A+AE+LG+G+ G++YKA++ T  AVVVKR K+MN V +E F   +RRLG L H N+L  + Y++R+EEKL++ +++  GSL   LHG+       L+WP RL+I++GI+RGL YL++ L SL +PHG+LKSSN+LL  + +PLL+DY   P+I++      + AY++PE  +  +I+ K DV+C GI+ILE+L GKFP  YL  S     D+V W    I + R +EVFD E+    NS  E++KLL IGV+C E + E+R D+ E + +IEE++
Sbjct:    8 VFFFTVVLLFPFSFSM-SDSEALLKLKQSF---TNTNALDSWEPGSGPCSGDK-EWGGLVCFNGIVTGLHLVGMGLSGKIDVEALIAITGLRTISIVNNSFSGSIPEFNRLGALKAIFISGNQFSGEIPPDYFVRMASLKKLWLSDNKFTGAIPLSIQLLSHLIELHLENNQFTGTIPDFNLPTLKSLNLSNNKLKGAIPDSLSKFGGSAFAGNAGLCGEELGNGCNDH---------------------GIDLGTDRSRKAIAVIISVAVVIISLLIIV---VFLMRRRKEEEFDVLENVDESVE-VRISGSSRKEGSSTSRRAIGSSRRGSNRSSQVKSSMKEDMVVVNEEKGIFGMSDLMKAAAEVLGTGSLGSAYKAVMATGIAVVVKRMKEMNRVSKEGFDLELRRLGSLQHPNVLNPLGYHFRKEEKLIIYEYIPKGSLLFVLHGDRGPSHAELNWPARLKIVQGIARGLGYLHTELASLDLPHGNLKSSNILLTFDHDPLLSDYGYSPLISVSFVSQALFAYRAPEAVRDNQISPKCDVYCLGIVILEILIGKFPTQYLNNS-KGGTDVVEWAVSAIADGREAEVFDPEIASSINSMEEMVKLLHIGVACAESNPEQRPDIKEAIRRIEEIH 615          

Query:   10 AKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGN-TANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLV 1479
            A L+RAPTP+    L +A +  +V +   S   S  D LLKF+  + LG+ T  L +W+  ++ C+ + T +W GV C+NG+V GL+LE LGL G +DL+ L+ L YL+T+SFMNN  +GPLP++KK   L+S+YLS NHFSG+IPDD F GM  L+K++LANN F+GKIPSSL TLPR+                     L  +N+S N L GP+P SL ++  S+F+GN  LCG P                              DSC +SKKPS                      + L+   +  +L G   +D  S  +  A SS ++  + E + H KRA+QGKL+FVR+DR+RFDL DLLRASAE+LGSG FG+SYKA++++ +A+V KRYKQMNNVGREEF EHMRRLGRL H NLLPLVAYYYR+EEKLLVS++VE GSLASHLHGNH+ D P L+WPTRLRIIKG+++GL YLY+ LPSL+
Sbjct:    6 ALLVRAPTPSP---LPIALILILVSIT-SSEAVSDADILLKFR--VSLGNAT-ALGDWNTSRSVCSTDQTESWNGVRCWNGSVWGLRLEGLGLNGAIDLDSLSSLRYLRTISFMNNSFEGPLPEIKKLVALKSVYLSNNHFSGDIPDDAFSGMAYLKKVHLANNKFTGKIPSSLATLPRLLH-------------------LANVNISNNMLGGPIPASLSRISSSSFSGNKDLCGKPL-----------------------------DSC-SSKKPSAVIVALIVVAIALILVTIGLLLLVLHRNIRTVQLGGAAPVDNHSM-SEVAHSSLVECGTSEMSGHSKRAEQGKLTFVRDDRERFDLQDLLRASAEVLGSGNFGSSYKAVLLSGEAMVAKRYKQMNNVGREEFQEHMRRLGRLAHPNLLPLVAYYYRKEEKLLVSEYVENGSLASHLHGNHSIDQPGLNWPTRLRIIKGVAKGLAYLYNELPSLI 440          

Query: 1039 KRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQVV 2007
            K+ +QG+L FVR DR+RF+L DLLRASAE+LGSG+FG+SYKA++++  A+VVKR+KQMN +G  +FHEHMRRLGRL+H NLL LVA+YY++EEKLLVSDFV  GSLASHLH       P LDWP RL+II+ ++  L YLY  L  L +PHGHLKSSNVLLD+ FEP+L+DYAL+P IN E AQ +M+AYKSPE+ Q+ R T+KTDVW  GI+ILE+LTGKFP NYLKQ   + +DL++WVN +++E+ T EVFD +M    N  GE+LKLLKIG+SCCE ++E+R DL E V++IEEL E +SD D  SS +SEGD Y+S+ +
Sbjct:  267 KKGEQGQLYFVRNDRERFELQDLLRASAEVLGSGSFGSSYKAVLLSGPAMVVKRFKQMNRLGSGDFHEHMRRLGRLSHPNLLSLVAFYYKKEEKLLVSDFVPNGSLASHLHSKRAPGQPGLDWPIRLKIIQKVAHALAYLYKELSDLTLPHGHLKSSNVLLDDKFEPVLSDYALVPAINREHAQQIMVAYKSPEFMQYDRTTRKTDVWSLGILILEMLTGKFPANYLKQGKGANSDLLSWVNSVVREEWTGEVFDKDMKGTRNGEGEMLKLLKIGMSCCEWNMEKRWDLKEAVKRIEELKERDSDED-NSSYASEGDIYSSRAM 589          

Query:  124 LLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGN 699
            L+KFK +L   S    L +W+   +PC+     W GV CF G V  LQLEN+GL G++D+E L +L  L+T+S M N   GP+P  K+   L+SLYLS N FSGE+P D F  M+ L+K++LA N F+GKIP SL  LPR+ +V LE N F G+IP F Q +L+ +N+S N LEG +P SL KMD S+F GN
Sbjct:   12 LVKFKASLFNAS---ALRDWNESSDPCSDGNG-WTGVKCFEGKVWTLQLENMGLAGQIDIESLKELQMLRTISIMGNSFGGPMPAFKRLAALKSLYLSNNRFSGELPHDAFAHMNWLKKVHLAQNEFTGKIPKSLAKLPRLLEVLLENNNFEGKIPKFPQNELQMVNMSNNALEGRIPASLSKMDRSSFIGN 199          

Query:   40 SFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFN--GNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIM-TDAVVVKRYKQMNNVGREEFHEHMRRLGRL-THENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESD 1950
            S + LF+  ++ ++ L     +D+   ALL F   +    K     NW+     C     +WVG+ C      VR L+L  +GL G +    L +L  L+ LS  +N+L G LP D+     L+ L+L +N+FSG+IP      + +L    L+ N+F+G IP ++  L ++  + L+ N  SG IPD     LK LN+S N L G +P SL++   S+F GN  LCGPP                              +  G+ KK S                           RK+ SE  G            A+G  + +    E     +  D+ KL F       FDL DLLRASAE+LG G++G +YKA++  +  VVVKR K++  VG+ +F + M  +GR+  H N++PL AYYY ++EKLLV D+V  GSL++ LHGN  +    LDW  R++I  GI+RG+T+++S        HG++KSSNVLL+++FE  ++D+ L P++N          Y++PE  + R+ T K+DV+ FG+++LE+LTGK P        D   DL  WV  +++E+ T+EVFD+E+ R  N   E++++L++ ++C  +  + R  ++EVV  IEE+ + +S+
Sbjct:   26 SLVLLFLFVIAILLPLAIAD-LDADKQALLDFADAVPHRRKL----NWNSSTPVCT----SWVGINCTGDGSRVRALRLPGIGLTGSIPATTLGKLDALEILSLRSNLLTGKLPSDIPSLPSLQYLFLQHNNFSGDIPASFSPQLTVLD---LSFNSFTGNIPLTIWNLTQLTGLNLQNNSLSGAIPDVNPSKLKHLNLSYNNLNGSIPSSLQRFPNSSFVGNSLLCGPPLNNCS------LTPLSPSPAPSFPSPPMASEKQGSKKKLSMGIIIAIAVGGAVVLFLVVLMIFLCCLRKKDSEGSGVAK-------GKASGGGRSEKPKEEFGSGVQEPDKNKLVFFEGCSYNFDLEDLLRASAEVLGKGSYGTAYKAVLEESTTVVVKRLKEVV-VGKRDFEQQMDIVGRVGQHPNVVPLRAYYYSKDEKLLVYDYVSGGSLSALLHGNRPTGRSPLDWNARVKISLGIARGITHIHSVGGGKFT-HGNIKSSNVLLNQDFEGCISDFGLTPLMNFPATSSRNAGYRAPEVIESRKHTHKSDVYSFGVLLLEMLTGKAP--LQSPGRDDMVDLPRWVQSVVREEWTAEVFDIELMRYQNIEEEMVQMLQLAMACVAKVPDMRPSMDEVVRMIEEIRQSDSE 638          

Query:   19 MRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCF--NGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTA--AAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            M   + A F+ L V  L+ +V+L      + T D         Q+  +  +   W+   + CN     WVGV C     NV  L+L  +GL G++    + +L  L+ LS  +N L G +P D      LRSLYL  N FSG  P    + +  L +L L++N F+G++P S+  L ++  + L+ N FSG IP      L   NVS N L G +PQ+L K   S+FAGN  LCG P    CNP                   K        SKK S                      +    R+QR +       + +    A  A  SS+ D+           AD+ KL F       FDL DLLRASAE+LG G+ G SYKA++     VVVKR K +  V ++EF   +  LG++ HEN++PL A+Y+ ++EKLLV DF+  GSL++ LHG+  S    LDW  R+RI    +RG+ +L+    S  V HG++KSSN+LL  + +  ++D+ L P+       + +  Y++PE  + R++T K+DV+ FG+++LE+LTGK P        +   DL  WV  +++E+ T+EVFDVE+ R  N   E+++LL+I ++C     ++R  + EVV  IE++  GE+D   R S
Sbjct:    1 MAVGSDAGFVFLTVL-LAWVVLLSGRVSSEPTQDKQTLLAFLSQIPHENRI--QWNASDSACN-----WVGVGCDANRSNVYTLRLPGVGLVGQIPENTIGRLSQLRVLSLRSNRLSGDIPRDFANLTLLRSLYLQDNLFSGGFPGSITQ-LTRLGRLDLSSNNFTGELPFSINNLNQLTGLFLQNNGFSGSIPSINSDGLDDFNVSNNRLNGSIPQTLFKFGSSSFAGNLALCGGPLP-PCNPFFPSPTPSPSIVPSNPVQKK--------SKKLSTAAIIAISVGSALILCLLLLFLLLCLRRRQRRQPPKPPKPETTRSIVAETATSSSKDDITGGSAE-----ADRNKLVFFEGGVYSFDLEDLLRASAEVLGKGSVGTSYKAVLEEGTTVVVKRLKDV-TVTKKEFEMQIDVLGKIKHENVVPLRAFYFSKDEKLLVYDFMAAGSLSALLHGSRGSGRTPLDWDNRMRIALSAARGIAHLH---VSGKVVHGNIKSSNILLRPDHDACVSDFGLNPLFGNSTPPNRVAGYRAPEVMETRKVTFKSDVYSFGVLLLELLTGKAPNQ--ASLGEEGIDLPRWVQSVVREEWTAEVFDVELMRYHNIEEEMVQLLQIAMACVSTVPDQRPAMQEVVRMIEDMNRGETDDGLRQS 627          

Query:   28 PTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQK--DLKRLNVSQNELEGPVPQSL-KKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVV-VKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYE-----GESDADYRSSVS 1974
            P   SF++L     S +++L     + + T AL +F+   Q      ++SNW    + C+G    W GV CF+G V  L L +L L+G +D   L+ L  L+ L    N L+G +  +     L+ +YL+ N FSGEIP D F  +  L +L L++N   G IP SL++LPR+  + LE N  SGQ+PD      +LK LN+S N   G +P+ + KK    +F GN  LCG     AC+                      T  S  T   P                            R++RS   G+ S  E  K  A+ G       S  TN      D+ KL F  + R++F+L DLLRASAE+LG G+ G  YKA++     V VKR K  N   R+EF ++M  +G+L H N++   AYYY +EEKLLV D++  GSL S LHGN       LDW TR+ ++ G +RGL  ++    +  +PHG++KSSN+LLD+N    ++D+ L  ++N   A   +  Y++PE  + +R+++K DV+ FG+++LEVLTG+ P  Y   S                     EVFD E+ R  N   EL+ +L++G++C     E+R  ++EV + IE++       GE   + R+S+S
Sbjct:    7 PFSLSFLSLS---FSLLLLLSPSLSLSNDTFALSQFRS--QTDVHGTLISNWTGA-DACSGV---WRGVRCFDGRVAVLSLPSLSLRGPIDA--LSGLNQLRILDLQGNRLNGTVLPIANCTNLKLVYLAGNDFSGEIPPD-FSSLRRLLRLDLSDNNLRGPIPGSLSSLPRLLTLRLENNVLSGQVPDLSASLPNLKELNLSNNGFYGHLPEGMAKKFGDRSFQGNEGLCGSSPLPACS----------------FTEASPTAASAQTGLSPGAIVAIVIANSAGSE-----------GGRRRRS---GSSSASEKKKVYASNGGG---ADSDGTNA----TDRSKLVFF-DRRKQFELEDLLRASAEMLGKGSLGTVYKAVLDDGCTVAVKRLKDANPCARKEFEQYMDVIGKLKHPNIVRFRAYYYAKEEKLLVYDYLPNGSLHSLLHGNRGPGRIPLDWTTRISLVLGAARGLARIHEEYTASKIPHGNVKSSNILLDKNGVACISDFGLALLLNPVHATARLGGYRAPEQLEIKRLSQKADVYSFGVLLLEVLTGRAPSQYPSPS--------------------PEVFDQELLRYKNIEEELVAMLQVGMACVVPQPEKRPTMSEVAKMIEDIRVEQSPLGEEYDESRNSLS 594          

Query:  178 NWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDA-VVVKRYKQMNNVGREEFHEHMRRLGRLT-HENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQ 2001
            NW P    C     +WVG+ C    V  L+L  +GL G +    L +L  LKTLS  +N L+G LP D+     L+ +YL +N+FSG IP        LL  L L+ N+  G IP+++  L  +  + L+ N  +G IP      L  +N+S N+L G +P   +K   S+F GN  LCG P     N                      + +   ++KK                        + L   K++   DG  ++ +  K   +  S + +    +     +  ++ KL+F       FDL DLLRASAE+LG G++G +YKA++     VVVKR K++   G+ EF +HM  +GR++ H N++PL AYYY ++EKLLV D++  GSL + LHGN + +  +L+W +R++I  G ++G+ +++S        HG++KSSNVLL ++ +  ++D+ L  ++N        + Y++PE  + R+ T+K+DV+ +G+++LE+LTGK P        D   DL  WV  +++E+ T+EVFDVE+ +  +   E++++L+I ++C  +  + R  + EVV  +EE+    SD++ R S  ++    T+Q
Sbjct:   45 NWSPATAIC----ISWVGIKCDGNRVVALRLPGVGLYGPIPANTLGKLDALKTLSLRSNHLNGNLPSDVLSLPSLQYMYLQHNNFSGNIPSSL---PPLLILLDLSFNSIVGNIPATIQNLTHLTGLNLQNNSLTGPIPVINLPRLNHVNLSYNDLNGSIPYFFRKFPASSFEGNSLLCGQPL----NHCSSVTPSPSPSPSSIPSPATVSPEPRASNKKKLSIGAIIAIAIGGSAVLCLLFVVILLCCLKKK---DGEGTVLQKGK---SLSSGKSEKPKEDFGSGVQEPEKNKLAFFEGSSYNFDLEDLLRASAEVLGKGSYGTAYKAILEEGTIVVVKRLKEVA-AGKREFEQHMEIVGRVSCHPNVVPLRAYYYSKDEKLLVYDYITGGSLFALLHGNRDPEKTLLNWESRVKIALGTAKGIVHIHSANGGKFT-HGNIKSSNVLLTQDVDGQISDFGLTSLMNYPLVTSRSLGYRAPEVIETRKSTQKSDVYSYGVLLLEMLTGKAPVQ--SPGRDDVVDLPRWVQSVVREEWTAEVFDVELMKDQSYEEEMVQMLQIAMACVAKMPDMRPKMEEVVRLMEEI--RPSDSENRPSSDNQSKGSTAQ 632          

Query:   19 MRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN------NRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGK 1698
            M  PT  S    F  ++    +L   +  D   +AL+ FK+T    +K   L+ W+   NPC+     W GV C    V  L LE L LQG    +PLA L  L+ LS   N L GP+P+L     L+ L+LSYN FSGE P      +  L +L L++N  SG+IP ++  L  +  + LE N+FSG I      +L+  NVS N L G +P++L     S F  N  LCG P    C                          + G     +                     + + N      + K    L+G + +  SS Y A AG                  ++G++ F  E  +RF+L DLLRASAE+LG G FG +YKA++   + V VKR K  +  G+ EF +HM  LGRL H N++ L AYY+ R+EKLLV D++  GSL   LHGN       LDW TRL+I  G +RGL +++++  +L + HG++KS+N+LLD+     ++D+  L V     A      Y++PE    R+ ++K+DV+ FG+++LE+LTGK
Sbjct:    1 MAKPTLTSLHFAFALFILHFFLLHASTSSD--LEALMAFKETADAANK---LTTWNVTVNPCS-----WYGVSCLQNRVSRLVLEGLDLQGSF--QPLASLTQLRVLSLKRNRLSGPIPNLSNLTALKLLFLSYNEFSGEFPAS-VTSLFRLYRLDLSHNNLSGQIPETVNHLAHILTLRLEENRFSGSITGLNLPNLQDFNVSGNRLAGDIPKTLSAFPVSAFDRNAVLCGSPMP-TCKNVAGDPTKPGSGGAIASPPQNTRHGATGKVSPVAMIAIILGDILVLAIVSLLLYCYFWRNYAGKMRDGKSSQILEGEKIVYSSSPYPAQAG-----------------YERGRMVFF-EGVKRFELEDLLRASAEMLGKGGFGTAYKAVLDDGNVVAVKRLKDAHVGGKREFEQHMEVLGRLRHPNVVNLRAYYFARDEKLLVYDYMPNGSLFWLLHGNRGPGRTPLDWTTRLKIAAGAARGLAFIHNSCKTLKLTHGNIKSTNILLDKCGSARVSDFG-LSVFASSTAAPRSNGYRAPEILDGRKGSQKSDVYSFGVLLLELLTGK 534          

Query:  916 NNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVE-TNPHPKRADQ------GKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            + RK+   + G E+LDE  +   + GS++    S++  N   +R  Q        L  + +++  F L DL++A+AE+LG+G  G++YKA++    AVVVKR +++N +GR+ F   +R++GRL HEN+L  +AY+YR+EEKLL+S++V  GSL   +HG+       L+WPTRL+II+GI+ G+ +L+S   SL +PHG+LKSSN+LLDE++ PLL DYA  P++N  QA   M AY+    AQ + ++ K DV+C GI+ILE++TGKFP  YL        D+V WV   I+E R +E+ D E+    + R E+ +LL+I   C E + E RLD+ E + +I+E+
Sbjct:  156 SRRKEEFNILGKENLDEVVEIQVS-GSTRKGADSLKKANGSSRRGSQHGRASVSDLVMINDEKGSFGLPDLMKAAAEVLGNGGLGSAYKAVMANGLAVVVKRMREINRLGRDSFDAQIRKIGRLRHENILTPLAYHYRKEEKLLISEYVPKGSLLYVMHGDRGISHSELNWPTRLKIIQGIASGMNFLHSEFASLDLPHGNLKSSNILLDEHYVPLLTDYAFYPLVNATQASQAMFAYR----AQDQHVSPKCDVYCLGIVILEIITGKFPSQYLSNG-KGGTDVVQWVKSAIEENRETELIDPEIASEASER-EMQRLLQIAAECTESNPENRLDMKEAIRRIQEI 495          

Query:    1 MAMAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSL 408
            MA  +L+       F  LF+++    + L       S  +ALLK KK+L     T  L +W P  NPC G    W G++C NG V GL+L ++ L G +D++ L  +  L+T+S  NN   GPLP   +   L+ +
Sbjct:    1 MAAVRLLLRSHLLIFFFLFLSFFPLSLSL-------SENEALLKLKKSLV---HTGALDSWVPSSNPCQGP---WDGLICLNGIVTGLRLGSMDLSGNIDVDALIDIRGLRTISLTNNSFSGPLPAFNRLGSLKEI 123          

Query:   43 FITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQR-----SELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQG-KLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEY--AQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRS 1965
            FI +F++ L  + M     P DS  D LL+FK TL  GS+     +WDP  +PC GNTANW GVLC N  V GLQLE +GL GKL+L+PL  +  L+T+SFMNN  +GP+P +K+F  L+SLYLS N FSGEIP D F GM LL+K+ LANNAF G IPSSL +LP + ++ L GN+F GQIP F QKDLK  +   N+L+GP+P+SL+ MDP +FAGN  LC  P    C+                      TG   G     S                     F F+ +R++          G E + ES  Y  +   +    +SV         D G +L FVR+D QRFDL DLLRASAE+LGSGTFGASYKA I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H N+LPLVAYYYRREEKLLV++F+   SLASHLH N+++    LDW TRL+IIKG+++GL+YL+  LP+L +PHGH+KSSN++LD++FEPLL DYAL P+++ E A + M AYKSPEY  ++ + ITKKTDVWCFG++ILEVLTG+FPENYL Q YDS   LV WVN M+KEK+T +VFD EM    N + E++ LLKIG+ CCEE+ ERR+D+ EVVE +E L EGES+ D+ S
Sbjct:   25 FIIIFISVLCPVAMSQVVVP-DSDADCLLRFKDTLANGSE---FRSWDPLSSPCQGNTANWFGVLCSN-YVWGLQLEGMGLTGKLNLDPLVPMKNLRTISFMNNNFNGPMPQVKRFTSLKSLYLSNNRFSGEIPADAFLGMPLLKKILLANNAFRGTIPSSLASLPMLLELRLNGNQFQGQIPSFQQKDLKLASFENNDLDGPIPESLRNMDPGSFAGNKGLCDAPLS-PCSSSSPGVPVVPVSPVDPKSTSPPTGKKAG-----SFYTLAIILIVIGIILVIIALVFCFVQSRRRNFLSAYPSSAGKERI-ESYNYHQSTNKNNKPAESVNHTRRGSMPDPGGRLLFVRDDIQRFDLQDLLRASAEVLGSGTFGASYKAAISSGQTLVVKRYKHMNNVGRDEFHEHMRRLGRLNHPNILPLVAYYYRREEKLLVTEFMPNSSLASHLHANNSAG---LDWITRLKIIKGVAKGLSYLFDELPTLTIPHGHMKSSNIVLDDSFEPLLTDYALRPMMSSEHAHNFMTAYKSPEYRPSKGQIITKKTDVWCFGVLILEVLTGRFPENYLTQGYDSNMSLVTWVNDMVKEKKTGDVFDKEMKGKKNCKAEMINLLKIGLRCCEEEEERRMDMREVVEMVEMLREGESEDDFGS 659          

Query:   67 LSCMVMLPFGSPMDSTTD--ALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGAC-NPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN----NRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHP---KR------ADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGE-SDADYRSSVSSEGDDYTSQ 2001
            L C+++  F +P    +D  A+LKFK++L +G +   L++W+ K  PC      W GVLC  G+V  LQ+ENL L G +D+E L+ L  L+TLSFMNN  +GP PD KK   L+SLYLS N F G+IP D FEGM  L+K++LA N F+G+IPSS+  LP++ ++ L+GN+F+G+IP+F +  L  LN+S N L GP+P+SL   DP  F GN  L G P +  C +P+                       S    K  S                        LN    N+K R  ++   S  +       A  S+ D K  +        KR       +  KLSF+REDR++FDL DLL+ASAEILGSG FGASYKA++ +   +VVKR+KQMNN GR+EF EHM+RLGRL H NLL +VAYYYR+EEKLLV DF E GSLA +LH N +   P LDWPTRL+I+KG+++GL YL+  LPSL+ PHGHLKSSNVLL + FEPLL DY L+P+IN E+AQ  M AY+SPEY QHRRITKKTDVW  GI+ILE+LTGKFP N+   S  S+ DL +WVN          +FD  MG+  +  G++LKLL IG++CCE DVE+RLD+ + VEKIEEL E E  D D+ S+  SE D  +S+
Sbjct:   18 LVCLLLF-FSTPTHGLSDSEAILKFKESLVVGQEN-ALASWNAKSPPCT-----WSGVLCNGGSVWRLQMENLELSGSIDIEALSGLTSLRTLSFMNNKFEGPFPDFKKLAALKSLYLSNNQFGGDIPGDAFEGMGWLKKVHLAQNKFTGQIPSSVAKLPKLLELRLDGNQFTGEIPEF-EHQLHLLNLSNNALTGPIPESLSMTDPKVFEGNKGLYGKPLETECDSPYIEHPP-----------------QSEARPKSSSRGPLVITAIVAALTILIILGVIFLLNRSYKNKKPRLAVETGPSSLQKKTGIREADQSRRDRKKADHRKGSGTTKRMGAAAGVENTKLSFLREDREKFDLQDLLKASAEILGSGCFGASYKAVLSSGQMMVVKRFKQMNNAGRDEFQEHMKRLGRLMHHNLLSIVAYYYRKEEKLLVCDFAERGSLAINLHSNQSLGKPSLDWPTRLKIVKGVAKGLFYLHQDLPSLMAPHGHLKSSNVLLTKTFEPLLTDYGLIPLINQEKAQMHMAAYRSPEYLQHRRITKKTDVWGLGILILEILTGKFPANF---SQSSEEDLASWVNSGFHGVWAPSLFDKGMGKTSHCEGQILKLLTIGLNCCEPDVEKRLDIGQAVEKIEELKEREGDDDDFYSTYVSETDGRSSK 652          

Query:  922 RKQRSELDGTES------LDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYE--GESDADYRSS--VSSEGDDYTSQVV 2007
            ++Q SE    +S       +E+ +  + A S  + V  +  +   KR DQ KL FVR D++RF L D+LRASAE+LGSG FG+SYKA + +  AVVVKR++ M+N+GREEF++HM+++GRL+H NLLPL+A+YYR+EEKLLV++++  GSLA+ LH N      VLDWP RL+I++G++RGL YLY   P L +PHGHLKSSNVLLD NFEPLL DYAL+PV+N +Q+Q  M+AYK+PE+ Q  R ++++DVW  GI+ILE+LTGKFP NYL+Q   +  +L  WV  + + + T++VFD EM        ++LKLLKIG+ CC+ D+E+R++L+E V++IEE+    G      RSS   +S+GD  +S+ +
Sbjct:  298 QQQHSEKSSQDSKVYRKLANETVQRDSTATSGAISVGGLSPD-EDKRGDQRKLHFVRNDQERFTLQDMLRASAEVLGSGGFGSSYKAALSSGRAVVVKRFRFMSNIGREEFYDHMKKIGRLSHPNLLPLIAFYYRKEEKLLVTNYISNGSLANLLHANRTPGQVVLDWPIRLKIVRGVTRGLAYLYRVFPDLNLPHGHLKSSNVLLDPNFEPLLTDYALVPVVNRDQSQQFMVAYKAPEFTQQDRTSRRSDVWSLGILILEILTGKFPANYLRQGKGADDELAAWVESVARTEWTADVFDKEMKAGKEHEAQMLKLLKIGLRCCDWDIEKRIELHEAVDRIEEVDRDAGGGQESVRSSYVTASDGDHRSSRAM 669          

Query:   58 VAYLSCMVMLPFGSPM--DSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTAN---WVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPP 720
            + Y   +++L F SP+  D   DALLKFK +L   S    L  WD  + PC+G+  +   W GV+C NG+V  L+LEN+ L G+LD++ L  +  LK++SFM N  +G +P  +     L  LYL++N F+GEI  D F GM  L K++L  N FSG+IP SL  LP++ ++ LE N F+G+IP F QK+L  +NV+ N+LEG +P +L  M+ + F+GN  LCG P
Sbjct:    9 IVYSLLLIVLLFVSPIYGDGDADALLKFKSSLVNASS---LGGWDSGEPPCSGDKGSDSKWKGVMCSNGSVFALRLENMSLSGELDVQALGSIRGLKSISFMRNHFEGKIPRGIDGLVSLAHLYLAHNQFTGEIDGDLFSGMKALLKVHLEGNRFSGEIPESLGKLPKLTELNLEDNMFTGKIPAFKQKNLVTVNVANNQLEGRIPLTLGLMNITFFSGNKGLCGAP 232          

Query:   31 TPA-SFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKK-NPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRS---------------ELDGTESLDESSKYTAAAGS-SQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALI-MTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQ-AQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEM---GRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESD 1950
            TP+ S +++F + L   + LP    + +   ALL F+  +  G +T +   WD K+ +PCN     W GVLC  G V  L+L    L G +       L  L+TLS   N L G LP DL     LR LYL  N FSGEIP+  F   +L+R L LA N FSG+I S    L R+  + LE NK SG + D +   L + NVS N L G +P+SL+K D  +F G   LCG P     N                        +     KK SG                     M L  +K                  E+ G ++  E+ +  +     S   VK+VE N    +    KL F     + FDL DLLRASAE+LG GTFG +YKA++     V VKR K +    RE F E +  +G + HENL+PL AYYY  +EKLLV DF+  GSL++ LHGN  +  P L+W  R  I  G +RGL YL+S  P  +  HG++KSSN+LL  + +  ++D+ L  +++      +    Y++PE    RR+++K DV+ FG+++LE+LTGK P N +    +   DL  WV+ + +E+  +EVFD E+     V +   E+ ++L++G+ C E+  ++R  + EVV +I+EL +  +D
Sbjct:    6 TPSMSNLSIFFSILLLSLPLPSIGDLAADKSALLSFRSAV--GGRTLL---WDVKQTSPCN-----WTGVLCDGGRVTALRLPGETLSGHIPEGIFGNLTQLRTLSLRLNGLTGSLPLDLGSCSDLRRLYLQGNRFSGEIPEVLFSLSNLVR-LNLAENEFSGEISSGFKNLTRLKTLYLENNKLSGSLLD-LDLSLDQFNVSNNLLNGSIPKSLQKFDSDSFVGTS-LCGKPLVVCSNEGTVPSQPISVGNIPGTVEGS---EEKKKRKKLSGGAIAGIVIGCVVGLSLIVMILMVLFRKKGNERTRAIDLATIKHHEVEIPGEKAAVEAPENRSYVNEYSPSAVKAVEVNSSGMK----KLVFFGNATKVFDLEDLLRASAEVLGKGTFGTAYKAVLDAVTLVAVKRLKDVTMADRE-FKEKIEVVGAMDHENLVPLRAYYYSGDEKLLVYDFMPMGSLSALLHGNKGAGRPPLNWEVRSGIALGAARGLDYLHSQDP--LSSHGNVKSSNILLTNSHDARVSDFGLAQLVSASSTTPNRATGYRAPEVTDPRRVSQKADVYSFGVVLLELLTGKAPSNSVMN--EEGMDLARWVHSVAREEWRNEVFDSELMSIETVVSVEEEMAEMLQLGIDCTEQHPDKRPVMVEVVRRIQELRQSGAD 644          

Query:   34 PASFITLFVAYLSCMVM-LPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKK-NPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRK---------------QRSELDG-TESLDESSKYT---AAAGSSQMDVKSVETN-PHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNV--GREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQ-HLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELL-KLLKIGVSCCEEDVERRLDLNEVVEKIEEL--YEGESDAD 1956
            P S + +   +LS +++ LP  S  D   D          +G +T     W+ K+ +PCN     W GV C +  V  L+L  + L G +       L  L+TLS   N L G LP DL     LR LYL  N FSGEIP+  F   HL+R L LA+N+F+G+I S  T L ++  + LE N+ SG IPD +   L + NVS N L G +P++L++ +  +F     LCG P +  C P                       +      K SG                     M L  +K               Q  E+ G  E++D  + Y+   AAA +   + K+ E N P  K     KL F     + FDL DLLRASAE+LG GTFG +YKA++  DAV V   K++ +V    +EF E +  +G + HENL+PL AYY+ R+EKLLV DF+  GSL++ LHGN  +    L+W  R RI  G +RGL YL+S   S    HG++KSSN+LL ++ +  ++D+ L  ++       +    Y++PE    +R+++K DV+ FG+++LE++TGK P N +    +   DL  WV  + +++   EVFD E+  +     E++ +++++G+ C  +  ++R +++EVV K+E L  Y G    +
Sbjct:    7 PNSSMAILSVFLSLLLLSLPLPSTQDLNADRTALLSLRSAVGGRT---FRWNIKQTSPCN-----WAGVKCESNRVTALRLPGVALSGDIPEGIFGNLTQLRTLSLRLNALSGSLPKDLSTSSNLRHLYLQGNRFSGEIPEVLFSLSHLVR-LNLASNSFTGEISSGFTNLTKLKTLFLENNQLSGSIPD-LDLPLVQFNVSNNSLNGSIPKNLQRFESDSFL-QTSLCGKPLK-LC-PDEETVPSQPTSGGNRTPPSVEGSEEKKKKNKLSGGAIAGIVIGCVVGFALIVLILMVLCRKKSNKRSRAVDISTIKQQEPEIPGDKEAVDNGNVYSVSAAAAAAMTGNGKASEGNGPATK-----KLVFFGNATKVFDLEDLLRASAEVLGKGTFGTAYKAVL--DAVTVVAVKRLKDVMMADKEFKEKIELVGAMDHENLVPLRAYYFSRDEKLLVYDFMPMGSLSALLHGNRGAGRSPLNWDVRSRIAIGAARGLDYLHSQGTS--TSHGNIKSSNILLTKSHDAKVSDFGLAQLVGSSATNPNRATGYRAPEVTDPKRVSQKGDVYSFGVVLLELITGKAPSNSVMN--EEGVDLPRWVKSVARDEWRREVFDSELLSLATDEEEMMAEMVQLGLECTSQHPDQRPEMSEVVRKMENLRPYSGSDQVN 652          

Query:  181 WDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQ------------MDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVV-VKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRV-GNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            W+    PC      W GV C +G V  L+L  +GL G L +  +  L  L+TLSF  N L+GPLP D      LR LYL  N FSGEIP   F   +++R + LA N F G+IP ++ +  R+  + L+ N+ +G IP+   K L++ NVS N+L G +P  L  M  + F GN  LCG P   AC  +                    T    G S K S                        L  +K++ ++  + S++ +   T++A  ++                 V  NP     D   L+F  +    FDL  LL+ASAE+LG GTFG+SYKA      VV VKR + +  V  +EF E ++ LG ++H NL+ L+AYY+ R+EKL+V +++  GSL++ LHGN  S    L+W TR  I  G +R ++YL+S        HG++KSSN+LL E+FE  ++DY L P+I+     + +  Y++PE    R+I++K DV+ FG++ILE+LTGK P +  +Q ++   DL  WV+ + +++  S+VFD E+ R   +S   +++LL IG+SC  +  + R  + EV   IEE+
Sbjct:   46 WNLTAPPCT-----WGGVQCESGRVTALRLPGVGLSGPLPIA-IGNLTKLETLSFRFNALNGPLPPDFANLTLLRYLYLQGNAFSGEIPSFLFTLPNIIR-INLAQNNFLGRIPDNVNSATRLATLYLQDNQLTGPIPEIKIK-LQQFNVSSNQLNGSIPDPLSGMPKTAFLGN-LLCGKPLD-ACPVNGTGNGTV-------------TPGGKGKSDKLSAGAIVGIVIGCFVLLLVLFLIVFCLCRKKKKEQVVQSRSIEAAPVPTSSAAVAKESNGPPAVVANGASENGVSKNPAAVSKD---LTFFVKSFGEFDLDGLLKASAEVLGKGTFGSSYKASFDHGLVVAVKRLRDV-VVPEKEFREKLQVLGSISHANLVTLIAYYFSRDEKLVVFEYMSRGSLSALLHGNKGSGRSPLNWETRANIALGAARAISYLHSR--DATTSHGNIKSSNILLSESFEAKVSDYCLAPMISPTSTPNRIDGYRAPEVTDARKISQKADVYSFGVLILELLTGKSPTH--QQLHEEGVDLPRWVSSITEQQSPSDVFDPELTRYQSDSNENMIRLLNIGISCTTQYPDSRPTMPEVTRLIEEV 613          

Query:   37 ASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGN----VRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHL-LRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQ----GACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIM-TDAVVVKRYKQMNNVGREEFHEHMRRLGRLT-HENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQS--YDSKA--DLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYE-GESDADYRSSVSSEGDDYTSQ 2001
            ASF  L +A  + +V     + + S   ALL F  ++    K     NW+   + C+    +W+G+ C   N    V  ++L  +GL G +    L +L  LK LS  +N L G LP D+     L  LYL +N+FSGE+  +    +   L  L L+ N+ SG IPS L  L ++  + L+ N F G I       +K +N+S N L GP+P+ LKK    +F GN  LCGPP      GA +P                     T +     ++ S                     F+    +K + E  G E +   ++          D  S   +P     ++ KL F       FDL DLL+ASAE+LG G+FG +YKA++  T AVVVKR +++    ++EF + M  +G++  H N +PL+AYYY ++EKLLV  ++  GSL   +HGN       +DW TR++I  G S+ ++YL+S    L   HG +KSSN+LL E+ EP L+D +L+ + N+       + Y +PE  + RR+++++DV+ FG++ILE+LTGK P   L Q    D +   DL  WV  +++E+ T+EVFDVE+ +  N   E++++L++ ++C   + E R  + EV   IE++    +S    ++  SSE     S+
Sbjct:   11 ASFFFLLLAATAVLV----SADLASDEQALLNFAASVPHPPKL----NWNKNLSLCS----SWIGITCDESNPTSRVVAVRLPGVGLYGSIPPATLGKLDALKVLSLRSNSLFGTLPSDILSLPSLEYLYLQHNNFSGELTTNSLPSISKQLVVLDLSYNSLSGNIPSGLRNLSQITVLYLQNNSFDGPIDSLDLPSVKVVNLSYNNLSGPIPEHLKKSPEYSFIGNSLLCGPPLNACSGGAISPSSNLPRPL-------------TENLHPVRRRQSKAYIIAIVVGCSVAVLFLGIVFLVCLVKKTKKEEGGGEGV--RTQMGGVNSKKPQDFGSGVQDP-----EKNKLFFFERCNHNFDLEDLLKASAEVLGKGSFGTAYKAVLEDTTAVVVKRLREVV-ASKKEFEQQMEIVGKINQHSNFVPLLAYYYSKDEKLLVYKYMTKGSLFGIMHGNRGDRG--VDWETRMKIATGTSKAISYLHS----LKFVHGDIKSSNILLTEDLEPCLSDTSLVTLFNLPTHTPRTIGYNAPEVIETRRVSQRSDVYSFGVVILEMLTGKTP---LTQPGLEDERVVIDLPRWVRSVVREEWTAEVFDVELLKFQNIEEEMVQMLQLALACVARNPESRPKMEEVARMIEDVRRLDQSQQLQQNRTSSEATSNVSE 640          

Query:   40 SFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPS-------GXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKR------ADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVV-VKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGE-LLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            S + LFV YL+ +      S ++S   ALL  + +++      +L N     +PCN     W GV C  G V  L+L   GL G L +  +  L  LKTLS   N L GP+P D      LR LYL  N FSGEIP   F    ++R + L  N FSG+IP ++ +  R+  + LE N+ SG IP+ +   L++ NVS N+L G +P SL     + F GN  LCG P    C                        GD+ G +  P                              +F   RK++ E +   S +  +   AA  S+ +  ++V   P  K       A    L+F  +    FDL  LL+ASAE+LG GT G+SYKA      VV VKR + +  V  +EF E +  LG ++H NL+ L+AYY+ R+EKLLV +++  GSL++ LHGN  +    L+W TR  I  G +R ++YL+S        HG++KSSN+LL +++E  ++DY L P+I+   A + +  Y++PE    R+I++K DV+ FG++ILE+LTGK P +  +Q  +   DL  WV  + +++  S+V D E+ R      E +++LLKIG+SC  +  + R  + EV   IEE+
Sbjct:   10 SVVFLFVFYLAAVT-----SDLESDRRALLAVRNSVR---GRPLLWNMSAS-SPCN-----WHGVHCDAGRVTALRLPGSGLFGSLPIGGIGNLTQLKTLSLRFNSLSGPIPSDFSNLVLLRYLYLQGNAFSGEIPSLLFTLPSIIR-INLGENKFSGRIPDNVNSATRLVTLYLERNQLSGPIPE-ITLPLQQFNVSSNQLNGSIPSSLSSWPRTAFEGN-TLCGKPLD-TCEAESPNG-----------------GDAGGPNTPPEKKDSDKLSAGAIVGIVIGCVVGLLLLLLILFCLCRKRKKE-ENVPSRNVEAPVAAATSSAAIPKETVVVVPPAKATGSESGAVNKDLTFFVKSFGEFDLDGLLKASAEVLGKGTVGSSYKASFEHGLVVAVKRLRDVV-VPEKEFRERLHVLGSMSHANLVTLIAYYFSRDEKLLVFEYMSKGSLSAILHGNKGNGRTPLNWETRAGIALGAARAISYLHSR--DGTTSHGNIKSSNILLSDSYEAKVSDYGLAPIISSTSAPNRIDGYRAPEITDARKISQKADVYSFGVLILELLTGKSPTH--QQLNEEGVDLPRWVQSVTEQQTPSDVLDPELTRYQPEGNENIIRLLKIGMSCTAQFPDSRPSMAEVTRLIEEV 615          

Query:   37 ASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVR--GLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPD-LKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLT-HENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQ-AQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEM-GRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            A+F+ L V   +  V     + ++S   ALL+F   +    K     NW+     C    A+W G+ C   N R   L+L   GL G L  +   +L  L+ +S  +N L G +P  +     +RSLY   N+FSG IP       H L  L L+ N+ SG IP+SL  L ++ D+ L+ N  SG IP+   + LK LN+S N L G VP S+K    S+F GN  LCG P      P                     T    GT+KK                        + L   K+R   DG +  D ++   A  G S  D K+ E     + A++ KL F       FDL DLLRASAE+LG G++G +YKA++     VVVKR K++   G+ EF + M  +GR++ H N+ PL AYY+ ++EKLLV D+ + G+ +  LHGN+      LDW TRLRI    +RG+++++S   + ++ HG++KS NVLL +     ++D+ + P+++         + Y++PE  + R+ T+K+DV+ FG+++LE+LTGK         ++   DL  WV  +++E+ T EVFDVE+  +  N   E++++L+I ++C  +  + R  + EVV  +EE+
Sbjct:    6 AAFLFLLV---TTFVSRCLSADIESDKQALLEFASLVPHSRKL----NWNSTIPIC----ASWTGITCSKNNARVTALRLPGSGLYGPLPEKTFEKLDALRIISLRSNHLQGNIPSVILSLPFIRSLYFHENNFSGTIPPVL---SHRLVNLDLSANSLSGNIPTSLQNLTQLTDLSLQNNSLSGPIPNLPPR-LKYLNLSFNNLNGSVPSSVKSFPASSFQGNSLLCGAPL----TPCPENTTAPSPSPTTPTEGPGTTNIGRGTAKKVLSTGAIVGIAVGGSVLLFIILAIITLCCAKKR---DGGQ--DSTAVPKAKPGRS--DNKAEEFGSGVQEAEKNKLVFFEGSSYNFDLEDLLRASAEVLGKGSYGTTYKAILEEGTTVVVKRLKEV-AAGKREFEQQMEAVGRISPHVNVAPLRAYYFSKDEKLLVYDYYQGGNFSMLLHGNNEGGRAALDWETRLRICLEAARGISHIHSASGAKLL-HGNIKSPNVLLTQELHVCVSDFGIAPLMSHHTLIPSRSLGYRAPEAIETRKHTQKSDVYSFGVLLLEMLTGKAAGK--TTGHEEVVDLPKWVQSVVREEWTGEVFDVELIKQQHNVEEEMVQMLQIAMACVSKHPDSRPSMEEVVNMMEEI 614          

Query:  181 WDPKKNPCNGNTANWVGVLCFNG--NVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTA-------AAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDAD 1956
            W+   + CN     WVGV C +   ++  L+L   GL G++    L +L  L+ LS  +N L G +P D      LRSLYL +N FSGE P   F  ++ L +L +++N F+G IP S+  L  +  + L  N FSG +P  +   L   NVS N L G +P SL +    +F GN  LCG P +   +                    K          K S                      +FL  RK+R   +      + +            A SS+ +V    +    +  ++ KL F       FDL DLLRASAE+LG G+ G SYKA++     VVVKR K +    ++EF   M  +G++ H N++PL AYYY ++EKLLV DF+  GSL++ LHG+  S    LDW  R+RI    +RGL +L+    S  + HG++K+SN+LL  N +  ++DY L  + +     + +  Y +PE  + R++T K+DV+ FG+++LE+LTGK P        +   DL  WV  +++E+ T+EVFDVE+ R  N   E+++LL+I ++C     ++R  + EV+  IE++   E+  D
Sbjct:   47 WNESDSACN-----WVGVECNSNQSSIHSLRLPGTGLVGQIPSGSLGRLTELRVLSLRSNRLSGQIPSDFSNLTHLRSLYLQHNEFSGEFPTS-FTQLNNLIRLDISSNNFTGSIPFSVNNLTHLTGLFLGNNGFSGNLPS-ISLGLVDFNVSNNNLNGSIPSSLSRFSAESFTGNVDLCGGPLKPCKSFFVSPSPSPSLINPSNRLSSK--------KSKLSKAAIVAIIVASALVALLLLALLLFLCLRKRRGSNEARTKQPKPAGVATRNVDLPPGASSSKEEVTGTSSGMGGE-TERNKLVFTEGGVYSFDLEDLLRASAEVLGKGSVGTSYKAVLEEGTTVVVKRLKDV-MASKKEFETQMEVVGKIKHPNVIPLRAYYYSKDEKLLVFDFMPTGSLSALLHGSRGSGRTPLDWDNRMRIAITAARGLAHLH---VSAKLVHGNIKASNILLHPNQDTCVSDYGLNQLFSNSSPPNRLAGYHAPEVLETRKVTFKSDVYSFGVLLLELLTGKSPNQ--ASLGEEGIDLPRWVLSVVREEWTAEVFDVELMRYHNIEEEMVQLLQIAMACVSTVPDQRPVMQEVLRMIEDVNRSETTDD 627          

Query:    7 MAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESL-DESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYT 1995
            +AK  RA T  S + L +A++  +V+  FGSP    +DALLKFK  L   +    +++W+P   PC    +NWVGVLC NG++RGLQLE++ L G +DL+ LA LP  +TLS M+N  DGPLPD KK  KL++LYLS N FSG+IPD+ FEGM  L++LYLANN  +GKIPSSL TL ++ ++ LEGN+F GQIP+F QK +K +NV+ NELEGP+P++L ++ P +FAGN  LCGPP  G C P                     T  S G  KK S                     F+  + +K +S +  T S  +E+S    A+    +  +  ET+ H K+AD GKL+F+++D ++FDL DLL ASAE+LGSGTFG+SYKA+++   VVVKRY+ M+NVGREEFHEHMRRLGRL H NLLPL AYY RR+EKLLV++F E GSLASHLHGNH+ +   L W  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLDE+FEPLL DYAL PV+N E A   MMAYKSPEYAQ  R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL  WVN M+KEKRTSEVFD E+     S+GE++KLLKIG+SCCEEDVERRLD+ EVVEKI+ L EG+ D +      SEG+ Y+
Sbjct:    7 VAKFARATT--SSLVLVLAFVLSIVVTSFGSP---DSDALLKFKDQL---ANNGAINSWNPSVKPCEWERSNWVGVLCLNGSIRGLQLEHMALSGDIDLDALAPLPSFRTLSLMDNNFDGPLPDFKKLGKLKALYLSNNRFSGDIPDNAFEGMGSLKRLYLANNLLTGKIPSSLATLSKLMELKLEGNQFQGQIPNFQQKSMKTVNVASNELEGPIPEALSRLSPHSFAGNKGLCGPPL-GPCIPSPPS-----------------TPKSNG--KKFSILYIVIIILIVLLMLAAIAFAFLLFSRKKCKSRIQRTASSPEENSNKMVASYYRDVHRELSETSSHAKKADHGKLTFLKDDIEKFDLQDLLTASAEVLGSGTFGSSYKAVVVGQPVVVKRYRHMSNVGREEFHEHMRRLGRLKHPNLLPLAAYYNRRDEKLLVTEFAENGSLASHLHGNHSPEEDGLHWHIRLKIVKGVARGLAFLYNELP-IIAPHGHLKSSNVLLDESFEPLLTDYALRPVVNPEHAHMFMMAYKSPEYAQQSRTSNKTDIWSFGILILEMLTGKFPENYLTPCYNSDADLATWVNNMVKEKRTSEVFDKEIVGTKYSKGEMIKLLKIGLSCCEEDVERRLDIKEVVEKIDVLKEGDEDEEL---YGSEGNAYS 638          

Query:    7 MAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADY 1959
            +A L RA T +S + L +A++  +V+  FGSP    +DALLKFK+ L      E +SNW+   NPC  + +NWVGVLCFNG + GLQLE++GL G +DL+ LA LP  +TLS M+N  DGPLPD KK  KL++LYLS N FSG+IPD  FEGM  L++L+LANN  +GKI SSL  LP++ ++ L+GN+F GQIP+F QK +K  NV+ NELEGP+P++L ++ P++FAGN  LCGPP  G C P                   K  G      KK S                     F+  + ++ +       S  E+S    ++    +  +  ETN H +  D GKLSF+++D ++FDL DLLRASAE+LGSGT+G+SYKA++    VVVKRY+ MNNV REEFHEHMRR+GRL H NLLPL AYYYRR+EKLLV+ F E GSLASHLHGNH+ +   LDW  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLDE+FEPLL DYAL PVIN E A   MMAYKSPEYAQH R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL  WVN M+KEKRTSEVFD EM    NS+GE++KLLKIG+SCCE++VERR D+ EVV+KIEEL EG+ D D+
Sbjct:    5 VAMLARATT-SSLVLLVLAFVLSIVVTSFGSP---DSDALLKFKEQLV---NNEGISNWNVSVNPCERDRSNWVGVLCFNGGIWGLQLEHMGLAGNIDLDALAPLPSFRTLSLMDNNFDGPLPDFKKLGKLKALYLSNNRFSGDIPDKAFEGMGSLKRLFLANNLLTGKIASSLAILPKLTELKLDGNQFEGQIPNFQQKGMKTANVANNELEGPIPEALSRLSPNSFAGNKGLCGPPL-GPCIPSPPSTP-------------KAHG------KKFSILYIVIIILIVLLILAAIAFAFLLFSRKESKRRTQRRAS--ENSNRIMSSYYRDVHREMPETNSHSRITDHGKLSFLKDDIEKFDLQDLLRASAEVLGSGTYGSSYKAVVGGQPVVVKRYRHMNNVEREEFHEHMRRIGRLKHPNLLPLAAYYYRRDEKLLVTVFAENGSLASHLHGNHSLEEDGLDWRIRLKIVKGVARGLAFLYNQLP-IIAPHGHLKSSNVLLDESFEPLLTDYALRPVINPEHAHVFMMAYKSPEYAQHGRSSNKTDIWSFGILILEILTGKFPENYLTPGYNSDADLATWVNNMVKEKRTSEVFDKEMLGTKNSKGEMIKLLKIGLSCCEQEVERRSDIKEVVDKIEELKEGDDDEDF 625          

Query:   10 AKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGN-TANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTS 1998
            A L+RAPTP+    L +A +  +V +   S   S  D LLKF+  + LG+ T  L +W+  ++ C+ + T +W GV C+NG+V GL+LE LGL G +DL+ L+ L YL+T+SFMNN  +GPLP++KK   L+S+YLS NHFSG+IPDD F GM  L+K++LANN F+GKIPSSL TLPR+  + L+GNKF GQIPDF QK L  +N+S N L GP+P SL ++  S+F+GN  LCG P                              DSC +SKKPS                      + L+   +  +L G   +D  S  +  A SS ++  + E + H KRA+QGKL+FVR+DR+RFDL DLLRASAE+LGSG FG+SYKA++++ +A+V KRYKQMNNVGREEF EHMRRLGRL H NLLPLVAYYYR+EEKLLVS++VE GSLASHLHGNH+ D P L+WPTRLRIIKG+++GL YLY+ LPSL+V HGHLKSSNVLLDE+F P+L DYALLPVIN E A+ LM+AYKSPE+AQH R TKKTDVW  GI+ILE+LTGKFP NYL    +S+ + + WVN +  ++   EVFD EMG   NS+GE+LKLLKIG++CCEEDVERR DL E ++ IEEL       +     + EGD++ S
Sbjct:    6 ALLVRAPTPSP---LPIALILILVSIT-SSEAVSDADILLKFR--VSLGNAT-ALGDWNTSRSVCSTDQTESWNGVRCWNGSVWGLRLEGLGLNGAIDLDSLSSLRYLRTISFMNNSFEGPLPEIKKLVALKSVYLSNNHFSGDIPDDAFSGMAYLKKVHLANNKFTGKIPSSLATLPRLLVLRLDGNKFEGQIPDFQQKHLANVNISNNMLGGPIPASLSRISSSSFSGNKDLCGKPL-----------------------------DSC-SSKKPSAVIVALIVVAIALILVTIGLLLLVLHRNIRTVQLGGAAPVDNHSM-SEVAHSSLVECGTSEMSGHSKRAEQGKLTFVRDDRERFDLQDLLRASAEVLGSGNFGSSYKAVLLSGEAMVAKRYKQMNNVGREEFQEHMRRLGRLAHPNLLPLVAYYYRKEEKLLVSEYVENGSLASHLHGNHSIDQPGLNWPTRLRIIKGVAKGLAYLYNELPSLIVAHGHLKSSNVLLDESFNPVLTDYALLPVINPEHARQLMVAYKSPEFAQHSRTTKKTDVWGLGILILEILTGKFPTNYLTVGNNSE-EGITWVNSIANQEWMMEVFDKEMGGTENSKGEMLKLLKIGLACCEEDVERRWDLKEAIKHIEEL-------EVTDGTNDEGDEFPS 624          

Query:   40 SFITLFVAYLSCMVMLPFGSPMD-------STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN---------NRKQRSELDGTESL--DESSKYTAAAGSSQMDVKSVETNPHPKRA---DQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            +FIT F+  + C V +    P         S  D LL+FK TL   S    +S+WDP  +PC  N+ NW GVLC  GNV GLQLE +GL GKLDLEPLA +  L+TLSFMNN  +G +P +K F  L+SLYLS N F+GEIP D F+GMH L+KL LANNAF G IPSSL  LP + ++ L GN+F G+IP F QKDLK  +   N+LEGP+P+SL  MDP +F+GN  LCGPP                           C+ DS  +   PS                      + L          + ++R  L    S   D + KY     + +       T+   +R    DQ KL F+++D QRFDL DLLRASAE+LGSG+FG+SYK  I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H NLLP+VAYYYRREEKLL+++F+   SLASHLH NH+ D P LDWPTRL+II+G+++GL YL++ L +L +PHGHLKSSNV+LDE+FEPLL DYAL PV+N EQ+ +LM++YKSPEY+    +TKKTDVWC G++ILE+LTG+FPENYL Q YD+   LV WV+ M+KEK+T +VFD EM    N + E+L LLKIG+SCCEED ERR+++ + VEKIE L EGE D D+ S+
Sbjct:   21 AFITTFLIIVLCPVTMVMSQPQADVLPLPASDADCLLRFKDTLVNAS---FISSWDPSISPCKRNSENWFGVLCVTGNVWGLQLEGMGLTGKLDLEPLAAIKNLRTLSFMNNKFNGSMPSVKNFGALKSLYLSNNRFTGEIPADAFDGMHHLKKLLLANNAFRGSIPSSLAYLPMLLELRLNGNQFHGEIPYFKQKDLKLASFENNDLEGPIPESLSNMDPVSFSGNKNLCGPPLS------------------------PCSSDSGSSPDLPSSPTEKNKNQSFFIIAIVLIVIGIILMIISLVVCILHTRRRKSLSAYPSAGQDRTEKYNYDQSTDKDKAADSVTSYTSRRGAVPDQNKLLFLQDDIQRFDLQDLLRASAEVLGSGSFGSSYKTGINSGQMLVVKRYKHMNNVGRDEFHEHMRRLGRLKHPNLLPIVAYYYRREEKLLIAEFMPNRSLASHLHANHSVDQPGLDWPTRLKIIQGVAKGLGYLFNELTTLTIPHGHLKSSNVVLDESFEPLLTDYALRPVMNSEQSHNLMISYKSPEYSLKGHLTKKTDVWCLGVLILELLTGRFPENYLSQGYDANMSLVTWVSNMVKEKKTGDVFDKEMTGKKNCKAEMLNLLKIGLSCCEEDEERRMEMRDAVEKIERLKEGEFDNDFAST 658          

Query:  109 STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN---------NRKQRSELDGTESL--DESSKYTAAAGSSQMDVKSVETNPHPKRA---DQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSS 1977
            S  D LLKFK TL   S    +S+WDP  +PC  N+ NW GVLC  GNV GLQLE +GL GKLDLEPLA +  L+TLSFMNN  +G +P +K    L+SLYLS N F+GEIP D F+GMH L+KL LANNAF G IPSSL +LP + ++ + GN+F GQIPDF QKDLK  +   N+LEGP+P SL  MDP +F+GN  LCGPP                           C+ DS  +   PS                      + L          + ++R  L    S   D + KY     + +       T+   +R    DQ KL F+++D QRFDL DLLRASAE+LGSG+FGASYK  I +   +VVKRYK MNNVGREEFH+HMRRLGRL H NLLP+VAYYYRREEKLL+++F+   SLASHLH NH+ D P LDWPTR++II+G+++GL YL++ L +L +PHGHLKSSNV+LDE+FEPLL DYAL PV+N EQ+ +LM++YKSPEY+    +TKKTDVWC G++ILE+LTG+FPENYL Q YD+   LV WV+ M+KEK+T +VFD EM    N + E+L LLKIG+SCCEED ERR+++ + VEKIE L EGE D D+ S+ ++
Sbjct:   51 SDADCLLKFKDTLVNAS---FISSWDPSISPCKRNSENWFGVLCVTGNVWGLQLEGMGLTGKLDLEPLAPIKNLRTLSFMNNKFNGSMPSVKNLGALKSLYLSNNRFTGEIPADAFDGMHHLKKLLLANNAFRGNIPSSLASLPMLLELRVNGNQFHGQIPDFKQKDLKLASFENNDLEGPIPGSLSNMDPGSFSGNKNLCGPPLS------------------------PCSSDSGSSPDLPSSPTEKNKNQSFFTIAIVLIVIGIILMIISLVVCILDTRKRKSLSAYPSAGQDRTEKYNYDQSTDKDKAADSVTSYTSRRGAVPDQNKLLFLQDDIQRFDLQDLLRASAEVLGSGSFGASYKTGINSGQTLVVKRYKHMNNVGREEFHDHMRRLGRLNHPNLLPIVAYYYRREEKLLIAEFMPNRSLASHLHANHSVDQPGLDWPTRVKIIQGVAKGLGYLFNELTTLTIPHGHLKSSNVVLDESFEPLLTDYALRPVMNSEQSHNLMISYKSPEYSLKGHLTKKTDVWCLGVLILELLTGRFPENYLSQGYDANMSLVTWVSNMVKEKKTGDVFDKEMTGKKNCKAEMLNLLKIGLSCCEEDEERRMEMRDAVEKIERLKEGEFDNDFASTTNN 661          

Query:   46 ITLFVAYLSCMVMLPFGSPMDSTTD--ALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQR-SELDGTESLDESSK------YTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            +   V   S  V + FG   ++ TD  ALLKFK  L     +  L NW+P   PC  + +NW+GVLC NG++ GL+LE++ L G +D++ L  LP+ +TLS M+N LDGP PD+KK  KL++LYLS N FSG+IPDD F+GM  L+++++ANN F+G IP SL TLPR+ ++ LEGN+F G IPDF Q  LK +N++ N+L GP+P SL K+DP +F+GN +LCGPP                              D C + +  S                      + +  RK R S+L+ T SL  +S       Y       QM V+ +      +R+D  +LSFVRED ++FDL+DLLRASAE+LGSGTFG+SYKA + +  A+VVKRY+ MNNVGREEFHEHMRRLGRL H NLL L AYYYRREEKLLV ++VE GSLAS LH N++ +   LDW TRLR+IKG+++GL YLY  LP ++VPHGHLKSSNVLLD + EPLL DYAL PVIN +QA +LM+AYKSPEYAQ+ R + KTD+W FGI+ILE+LTGKFPENYL   YD+ ADL +WVN M+KEKRTSEVFD +M     S+GE++ +LKIG+SCCEEDVE R+D+ +VVEK+E+L EG+S+ +Y  S
Sbjct:   24 VVALVLASSSFVHMAFG---ENATDSVALLKFKDAL---GNSSALYNWNPIFPPCEWDRSNWIGVLCLNGSIWGLKLEHMSLAGSIDVDSLLPLPFFRTLSLMDNDLDGPFPDIKKLGKLKALYLSNNRFSGQIPDDAFQGMGSLKRVFMANNMFTGNIPLSLATLPRLMELRLEGNQFKGLIPDFQQHVLKTVNLASNQLVGPIPTSLSKLDPDSFSGNKELCGPPL-----------------------------DPCSSPENKSNVLKIIITVMVVLLIVAAVAFALAVLWRKSRGSQLERTSSLSANSNKIAPNTYVGDQEQIQMPVEQL------RRSD--RLSFVREDVEKFDLNDLLRASAEVLGSGTFGSSYKASVGSGVALVVKRYRHMNNVGREEFHEHMRRLGRLQHPNLLRLAAYYYRREEKLLVYEYVEHGSLASRLHSNNSLEGQGLDWHTRLRVIKGVAKGLAYLYGELP-ILVPHGHLKSSNVLLDPSLEPLLTDYALRPVINPQQAHNLMIAYKSPEYAQNGRTSNKTDIWSFGILILEILTGKFPENYLTAGYDTSADLASWVNKMVKEKRTSEVFDKDMKGAKYSKGEMINVLKIGLSCCEEDVESRVDIEQVVEKLEQLKEGDSEGEYYGS 630          

Query:   43 FITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLD----ESSKYTAAAGSSQMDVKSVETNPHPKRADQ----GKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEY--AQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRS 1965
            F+ +F++ L  + M     P DS  D LL+FK TL  GS+    ++WDP  +PC GNTANW GVLC N  V GLQLE +GL GKL+L+PL  +  L+T+SFMNN  +GP+P +K+F  L+SLYLS N FSGEIP D F GM LL+K+ LANNAF G IPSSL +LP + ++ L GN+F GQIP F QKDLK  +   N+L+GP+P+SL+ MDP +FAGN  LC  P    C+P                     TG   G     S                     F F+  R+ R+ L    S      ES  Y  +A  +    +SV    H +R       G+L FVR+D QRF L DLLRASAE+LGSGTFGASYKA I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H N+LPLVA     EEKLL++  +   SLA+HLH NH++    LDW TRL+IIKG+++GL+YL+  LP+L +PHGH+KSSN++LDE+FEPLL DYAL PV++ E A + M AYKSPEY  ++ + ITKKTDVWCFG++ILEVLTG+FPENYL Q YDS   LV WVN M+KEK+T +VFD EM    N + E++ LLK+G+ CCEE+ ERR+D+ EVVE IE L EGES+ D+ S
Sbjct:   25 FLIIFISVLCPVAMSQVVVP-DSDADCLLRFKDTLANGSE---FTSWDPLTSPCQGNTANWFGVLCSN-YVWGLQLEGMGLTGKLNLDPLVPMKNLRTISFMNNNFNGPMPQVKRFTSLKSLYLSNNRFSGEIPADAFRGMPLLKKILLANNAFRGTIPSSLASLPMLLELRLNGNQFQGQIPSFQQKDLKLASFENNDLDGPIPESLRNMDPGSFAGNKDLCDAPLS-PCSPSSPGVPVVPVSPVDPKSTSPSTGKKTG-----SFYTLAIILIVIGIILVIIALVFFFVQTRR-RNFLSAYPSAGKERIESYNYHQSASKNNKPAESVVN--HTRRGSMPDPGGRLLFVRDDIQRFGLQDLLRASAEVLGSGTFGASYKAAISSGQTLVVKRYKHMNNVGRDEFHEHMRRLGRLNHPNILPLVALLLP-EEKLLITQLMPNSSLANHLHANHSAG---LDWITRLKIIKGVAKGLSYLFDELPTLTIPHGHIKSSNIVLDESFEPLLTDYALRPVMSSEHAHNFMTAYKSPEYRPSKGQVITKKTDVWCFGVLILEVLTGRFPENYLTQGYDSNMSLVTWVNDMVKEKKTGDVFDKEMKGKKNCKAEMINLLKVGLRCCEEEEERRMDMREVVEMIEMLREGESEDDFGS 658          

Query:   52 LFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMD-VKSVETNPHP-KRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQV 2004
            +F+  +S + +        S ++ LL+FK +L+       L +W+    PC G+   WVGV+C NG+V GLQLE +GL G +D++ LA+LP+L+ +SFMNN  DG +P +KK   L+S++LS N FSGEI DD F GM  L+K++LA+N FSG +P SL  LPR+ ++ LEGN F GQIP+F    L+  N+S N LEGP+P+SL+KM+ ++F+GN  LCG P                               SC   KKP+                     F+ L   K ++ L   E+    SK T      ++D VK  E+N    K+ +QGKL ++R D  + DL DLL+ASAEILGSG FG+SYKA+++   +VVVKR++ MNNVG+EEF EHMRRLGRL H NLLP VAYYYR EEKLLV+DF++ GSLA HLHGNH  D P LDW TRL+IIKGI++GL YLY+ LP+L+ PH HLKSSNVLL ++F PLL DY L+P+IN E AQ LM+AYKSPEY QH RITKKTDVW FG +ILE+LTGKFP   L+Q   S  DL +WVN + +E+   EVFD EMG   NS+ E++KLLKIG++CCE DV +R D+ E VEKIEEL E +S+ D+ SS +SE +  + Q+
Sbjct:   11 IFLVIISVVHINVASGAKPSQSEILLEFKNSLR---NVTALGSWNTSTTPCGGSPGGWVGVICINGDVWGLQLEGMGLMGTIDMDTLAKLPHLRGISFMNNHFDGAIPKIKKLSALKSVFLSNNQFSGEIEDDAFSGMVSLKKVHLAHNKFSGGVPESLALLPRILELRLEGNHFKGQIPEFRATQLQSFNISNNNLEGPIPESLRKMELTSFSGNKNLCGAPL-----------------------------GSCPRPKKPTTLMMVVVGIVVALALSAIIVAFILLRCSKCQTTLVQVET--PPSKVTCR----ELDKVKLQESNTESGKKVEQGKLYYLRNDENKCDLKDLLKASAEILGSGYFGSSYKAVLVNGSSVVVKRFRHMNNVGKEEFQEHMRRLGRLNHPNLLPFVAYYYREEEKLLVTDFIDNGSLAIHLHGNHARDQPRLDWATRLKIIKGIAKGLAYLYTELPTLIAPHSHLKSSNVLLSKSFTPLLTDYGLVPLINQEIAQALMVAYKSPEYKQHGRITKKTDVWSFGTLILEILTGKFPTQNLQQGQASDTDLASWVNSVSQEEWEDEVFDKEMGGTTNSKWEMVKLLKIGLACCEGDVGKRWDMKEAVEKIEELKEKDSEDDFYSSYASEMESPSRQL 626          

Query:   52 LFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMD-VKSVETNPHP-KRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQV 2004
            +F+  +S + +        S ++ LL+FK +L+       L +W+    PC G+   WVGV+C NG+V GLQLE +GL G +D++ LA+LP+L+ +SFMNN  DG +P +KK   L+S++LS N FSGEI DD F GM  L+K++LA+N FSG +P SL  LPR+ ++ LEGN F GQIP+F    L+  N+S N LEGP+P+SL+KM+ ++F+GN  LCG P                               SC   KKP+                     F+ L   K ++ L   E+    SK T      ++D VK  E+N    K+ +QGKL ++R D  + DL DLL+ASAEILGSG FG+SYKA+++   +VVVKR++ MNNVG+EEF EHMRRLGRL H NLLP VAYYYR EEKLLV+DF++ GSLA HLHGNH  D P LDW TRL+IIKGI++GL YLY+ LP+L+ PH HLKSSNVLL  +F PLL DY L+P+IN E AQ LM+AYKSPEY QH RITKKTDVW FG +ILE+LTGKFP   L+Q   S  DL +WVN + +E+   EVFD EMG   NS+ E++KLLKIG++CCE DV +R D+ E VEKIEEL E +S+ D+ SS +SE +  + Q+
Sbjct:   11 IFLVIISVVHINVASGAKPSQSEILLEFKNSLR---NVTALGSWNTSTTPCGGSPGGWVGVICINGDVWGLQLEGMGLMGTIDMDTLAKLPHLRGISFMNNHFDGAIPKIKKLSALKSVFLSNNQFSGEIEDDAFSGMVSLKKVHLAHNKFSGGVPESLALLPRILELRLEGNHFKGQIPEFRATQLQSFNISNNNLEGPIPESLRKMELTSFSGNKNLCGAPL-----------------------------GSCPRPKKPTTLMMVVVGIVVALALSAIIVAFILLRCSKCQTTLVQVET--PPSKVTCR----ELDKVKLQESNTESGKKVEQGKLYYLRNDENKCDLKDLLKASAEILGSGYFGSSYKAVLVNGSSVVVKRFRHMNNVGKEEFQEHMRRLGRLNHPNLLPFVAYYYREEEKLLVTDFIDNGSLAIHLHGNHARDQPRLDWATRLKIIKGIAKGLAYLYTELPTLIAPHSHLKSSNVLLSXSFTPLLTDYGLVPLINQEIAQALMVAYKSPEYKQHGRITKKTDVWSFGTLILEILTGKFPTQNLQQGQASDTDLASWVNSVSQEEWEDEVFDKEMGGTTNSKWEMVKLLKIGLACCEGDVGKRWDMKEAVEKIEELKEXDSEDDFYSSYASEMESPSRQL 626          

Query:  115 TDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTG-DSCGTSKKPS-GXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMD----VKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSY-DSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQ 2001
            ++ LLKFK +L   S    L+NW     PCNG+T+NW GV+C    V GLQLE +GL GK+D + L   P L+T+SFMNN  DGPLP++KK   LRS+YLS NHFSGEIPD+ FEG+  L+K++LA+N F G IPSSL  LP++ D+ LEGNKFSG++P+F +K    LNVS NEL GP+P+SL K D ++F+GN  LCG P                          +C G +S   SKKP                       F+    RK+ S+   T      S      G + ++      S E + H K+ +  KLSFVR+DR+RFDLHDLL+ASAEILGSG FG+SYKA + T   +VVKR+KQMNNVG+EEF EHMRRLGRL H NLLPLVAYYYR+EEKLLV+D+VE GSLA HLHG+     P +DW  RL++ KGI +GL YL+  LPS++  HGHLKSSNVL+DE  EPLL DY L+PVIN E AQ LM+AY+SPEY Q  RITKKTDVW  GI+ILE+LTGKFP N+L Q   + + DL +WVN + +E+  S+VFD E+    ++  E+ KLLKIG+SCCE DVE+RLDL E VE+I ++ E +SD D  SS +SE D  +S+
Sbjct:   49 SENLLKFKDSL---SNASALANWSENIKPCNGDTSNWNGVICVKNYVWGLQLERMGLTGKIDFQILESFPELRTISFMNNSFDGPLPEIKKLGALRSIYLSNNHFSGEIPDNAFEGLLKLKKVFLAHNGFEGAIPSSLANLPKLLDLRLEGNKFSGKLPNFKEK-FASLNVSNNELGGPIPESLSKFDLTSFSGNKGLCGWPLS------------------------QCDGSNSSSISKKPPLASIVVVAIVVAVAIAAIVGAAFILFTRRKRTSKTIETPPPPPPSNLQKKTGINDVEQGLQAGSSEQSSHDKKTEITKLSFVRDDRERFDLHDLLKASAEILGSGCFGSSYKAALSTGPTMVVKRFKQMNNVGKEEFQEHMRRLGRLRHPNLLPLVAYYYRKEEKLLVTDYVEKGSLAVHLHGHQALGQPNMDWSIRLKVAKGIGKGLVYLHKELPSIIAAHGHLKSSNVLIDECNEPLLTDYGLVPVINQENAQELMVAYRSPEYLQLSRITKKTDVWNLGILILELLTGKFPTNFLPQGKGNEEEDLASWVNSIPEEEWMSKVFDKEIKASKSNESEMKKLLKIGLSCCEGDVEKRLDLREAVERINQVKEKDSDDDLFSSCASEVDTKSSR 657          

Query:   40 SFITLFVAYLSCMVMLPFGSPMD-------STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN---------NRKQRSELDGTESL--DESSKYTAAAGSSQMDVKSVETNPHPKRA---DQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            +FIT F+  + C V +    P         S  D LL+FK TL   S    +S+WDP  +PC  N+ NW GVLC  GNV GLQLE +GL GKLDLEPLA +  L+TLSFMNN  +G +P +K F  L+SLYLS N F+GEIP D F+GMH L+KL LANNAF G IPSSL  LP + ++ L GN+F G+IP F QKDLK  +   N+LEGP+P+SL  MDP +F+GN  LCGPP                           C+ DS  +   PS                      + L          + ++R  L    S   D + KY     + +       T+   +R    DQ KL F+++D QRFDL DLLRASAE+LGSG+FG+SYK  I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H NLLP+VAYYYRREEKLL+++F+   SLASHLH NH+ D P LDWPTRL+II+G+++GL YL++ L +L +PHGHLKSSNV+LDE+FEPLL DYAL PV+N EQ+ +LM++YKSPEY+    +TKKTDVWC G++ILE+LTG+FPENYL Q YD+   LV WV+ M+KEK+T +VFD EM    N + E+L LLKIG+SCCEED ERR+++ + VEKIE L EGE D D+ S+
Sbjct:   21 AFITTFLIIVLCPVTMVMSQPQADVLPLPASDADCLLRFKDTLVNAS---FISSWDPSISPCKRNSENWFGVLCVTGNVWGLQLEGMGLTGKLDLEPLAAIKNLRTLSFMNNKFNGSMPSVKNFGALKSLYLSNNRFTGEIPADAFDGMHHLKKLLLANNAFRGSIPSSLAYLPMLLELRLNGNQFHGEIPYFKQKDLKLASFENNDLEGPIPESLSNMDPVSFSGNKNLCGPPLS------------------------PCSSDSGSSPDLPSSPTEKNKNQSFFIIAIVLIVIGIILMIISLVVCILHTRRRKSLSAYPSAGQDRTEKYNYDQSTDKDKAADSVTSYTSRRGAVPDQNKLLFLQDDIQRFDLQDLLRASAEVLGSGSFGSSYKTGINSGQMLVVKRYKHMNNVGRDEFHEHMRRLGRLKHPNLLPIVAYYYRREEKLLIAEFMPNRSLASHLHANHSVDQPGLDWPTRLKIIQGVAKGLGYLFNELTTLTIPHGHLKSSNVVLDESFEPLLTDYALRPVMNSEQSHNLMISYKSPEYSLKGHLTKKTDVWCLGVLILELLTGRFPENYLSQGYDANMSLVTWVSNMVKEKKTGDVFDKEMTGKKNCKAEMLNLLKIGLSCCEEDEERRMEMRDAVEKIERLKEGEFDNDFAST 658          

Query:   43 FITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQR-----SELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQG-KLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEY--AQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRS 1965
            FI +F++ L  + M     P DS  D LL+FK TL  GS+     +WDP  +PC GNTANW GVLC N  V GLQLE +GL GKL+L+PL  +  L+T+SFMNN  +GP+P +K+F  L+SLYLS N FSGEIP D F GM LL+K+ LANNAF G IPSSL +LP + ++ L GN+F GQIP F QKDLK  +   N+L+GP+P+SL+ MDP +FAGN  LC  P    C+                      TG   G     S                     F F+ +R++          G E + ES  Y  +   +    +SV         D G +L FVR+D QRFDL DLLRASAE+LGSGTFGASYKA I +   +VVKRYK MNNVGR+EFHEHMRRLGRL H N+LPLVAYYYRREEKLLV++F+   SLASHLH N+++    LDW TRL+IIKG+++GL+YL+  LP+L +PHGH+KSSN++LD++FEPLL DYAL P+++ E A + M AYKSPEY  ++ + ITKKTDVWCFG++ILEVLTG+FPENYL Q YDS   LV WVN M+KEK+T +VFD EM    N + E++ LLKIG+ CCEE+ ERR+D+ EVVE +E L EGES+ D+ S
Sbjct:   25 FIIIFISVLCPVAMSQVVVP-DSDADCLLRFKDTLANGSE---FRSWDPLSSPCQGNTANWFGVLCSN-YVWGLQLEGMGLTGKLNLDPLVPMKNLRTISFMNNNFNGPMPQVKRFTSLKSLYLSNNRFSGEIPADAFLGMPLLKKILLANNAFRGTIPSSLASLPMLLELRLNGNQFQGQIPSFQQKDLKLASFENNDLDGPIPESLRNMDPGSFAGNKGLCDAPLS-PCSSSSPGVPVVPVSPVDPKSTSPPTGKKAG-----SFYTLAIILIVIGIILVIIALVFCFVQSRRRNFLSAYPSSAGKERI-ESYNYHQSTNKNNKPAESVNHTRRGSMPDPGGRLLFVRDDIQRFDLQDLLRASAEVLGSGTFGASYKAAISSGQTLVVKRYKHMNNVGRDEFHEHMRRLGRLNHPNILPLVAYYYRREEKLLVTEFMPNSSLASHLHANNSAG---LDWITRLKIIKGVAKGLSYLFDELPTLTIPHGHMKSSNIVLDDSFEPLLTDYALRPMMSSEHAHNFMTAYKSPEYRPSKGQIITKKTDVWCFGVLILEVLTGRFPENYLTQGYDSNMSLVTWVNDMVKEKKTGDVFDKEMKGKKNCKAEMINLLKIGLRCCEEEEERRMDMREVVEMVEMLREGESEDDFGS 659          

Query:   67 LSCMVMLPFGSPMDSTTD--ALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGAC-NPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN----NRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHP---KR------ADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGE-SDADYRSSVSSEGDDYTSQ 2001
            L C+++  F +P    +D  A+LKFK++L +G +   L++W+ K  PC      W GVLC  G+V  LQ+ENL L G +D+E L+ L  L+TLSFMNN  +GP PD KK   L+SLYLS N F G+IP D FEGM  L+K++LA N F+G+IPSS+  LP++ ++ L+GN+F+G+IP+F +  L  LN+S N L GP+P+SL   DP  F GN  L G P +  C +P+                       S    K  S                        LN    N+K R  ++   S  +       A  S+ D K  +        KR       +  KLSF+REDR++FDL DLL+ASAEILGSG FGASYKA++ +   +VVKR+KQMNN GR+EF EHM+RLGRL H NLL +VAYYYR+EEKLLV DF E GSLA +LH N +   P LDWPTRL+I+KG+++GL YL+  LPSL+ PHGHLKSSNVLL + FEPLL DY L+P+IN E+AQ  M AY+SPEY QHRRITKKTDVW  GI+ILE+LTGKFP N+   S  S+ DL +WVN          +FD  MG+  +  G++LKLL IG++CCE DVE+RLD+ + VEKIEEL E E  D D+ S+  SE D  +S+
Sbjct:   18 LVCLLLF-FSTPTHGLSDSEAILKFKESLVVGQEN-ALASWNAKSPPCT-----WSGVLCNGGSVWRLQMENLELSGSIDIEALSGLTSLRTLSFMNNKFEGPFPDFKKLAALKSLYLSNNQFGGDIPGDAFEGMGWLKKVHLAQNKFTGQIPSSVAKLPKLLELRLDGNQFTGEIPEF-EHQLHLLNLSNNALTGPIPESLSMTDPKVFEGNKGLYGKPLETECDSPYIEHPP-----------------QSEARPKSSSRGPLVITAIVAALTILIILGVIFLLNRSYKNKKPRLAVETGPSSLQKKTGIREADQSRRDRKKADHRKGSGTTKRMGAAAGVENTKLSFLREDREKFDLQDLLKASAEILGSGCFGASYKAVLSSGQMMVVKRFKQMNNAGRDEFQEHMKRLGRLMHHNLLSIVAYYYRKEEKLLVCDFAERGSLAINLHSNQSLGKPSLDWPTRLKIVKGVAKGLFYLHQDLPSLMAPHGHLKSSNVLLTKTFEPLLTDYGLIPLINQEKAQMHMAAYRSPEYLQHRRITKKTDVWGLGILILEILTGKFPANF---SQSSEEDLASWVNSGFHGVWAPSLFDKGMGKTSHCEGQILKLLTIGLNCCEPDVEKRLDIGQAVEKIEELKEREGDDDDFYSTYVSETDGRSSK 652          

Query:   52 LFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXX---FMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHP--KRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAV-VVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYE--GESDADYRSSVSSEGDDYTSQ 2001
            +FV+ +S   M+  G    S T+ LLKFK +L +G +   L +W+ +  PC      W GVLC  G V GL+LENL L G +D+E L  L  L++LSF+NN   GP P+ KK   L+SLYLS N F  EIP D F+GM  L+KL+L  N F G+IP+SL   P++ ++ L+GN+F+GQIP+F       LN+S N L G +P S   MDP  F GN  LCG P    C+                      + +   ++KK S                           +  RK++  L   E    S +  A    S+    S  +      K     KLSF+R+D+ +F+L DLL+ASAEILGSG FGASYK L+   +V VVKR+K MN+ G +EF EHM+RLGRL HENLLP+VAYYY++EEKL VSDFV  GSLA+HLHG+ +   P LDWPTR  I+KG+ RGL YL+  LPSL+ PHGHLKSSNVLL E FEPLL DY L+P+IN E AQ LM+AYKSPEY +  R+TKKTDVW  G++ILE+LTGK  E++ +   +S+ DL +WV    K + T E+FD EMG+  N    +L L++IG+SCCE DVE+RLD+ E VEK+E+L +   + D D+ S+ +SE D  +S+
Sbjct:    7 MFVSIVSVFFMVVNGV---SETETLLKFKNSLVIG-RANALESWNRRNPPCK-----WTGVLCDRGFVWGLRLENLELSGSIDIEALMGLNSLRSLSFINNKFKGPFPEFKKLVALKSLYLSNNQFDLEIPKDAFDGMGWLKKLHLEQNNFIGEIPTSLVKSPKLIELRLDGNRFTGQIPEFRHHP-NMLNLSNNALAGQIPNSFSTMDPKLFEGNKGLCGKPLDTKCSSPYNH-----------------SSEPKSSTKKTSSKFLYIVAAAVAALAASLIIIGVVIFLIRRRKKKQPLLSAEPGPSSLQMRAGIQESERGQGSYHSQNRAAKKMIHTTKLSFLRDDKGKFELQDLLKASAEILGSGCFGASYKTLLSNGSVMVVKRFKHMNSAGIDEFQEHMKRLGRLNHENLLPIVAYYYKKEEKLFVSDFVANGSLAAHLHGHKSLGQPSLDWPTRFNIVKGVGRGLLYLHKNLPSLMAPHGHLKSSNVLLSEKFEPLLMDYGLIPMINEESAQELMVAYKSPEYVKQSRVTKKTDVWGLGVLILEILTGKLLESFSQVDKESEEDLASWVRSSFKGEWTQELFDQEMGKTSNCEAHILNLMRIGLSCCEVDVEKRLDIREAVEKMEDLMKEREQGDDDFYSTYASEADGRSSR 637          

Query:  109 STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGN-VRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQ--KDLKRLNVSQNELEGPVPQSL--KKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESL------------------DESSKYTAAAGSSQM----DVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            S ++ L++FK+++ +      L++W    +PCNG    W G+ C  G  V G+ +  LGL G +++E L  LP L+T+   NN+L GPLP   K   L+SL LS N FSGEI DD F+    L++++L NN  SGKIP+SL  L  + ++ ++GN+F+G+IP      K LK L++S N+LEG +P ++  +K     F GN +LCG P    C+                    K +    G  K  +                       +   R+    + G + L                  D S K + A GSS+     + K     P    +  G +  V  ++  F L DL++A+AE+LG+G+ G++YKA++    +VVVKR + MN + RE F   M+R G+L H N+L  +AY+YRREEKL+VS+++   SL   LHG+       L W TRL+II+G++RG+ +L+    S  +PHG+LKSSNVLL E +EPL++DYA LP++    A   + A+KSPE+ Q+++++ K+DV+C GII+LEV+TGKFP  YL        D+V WV   I + +  E+ D E+    +S  ++++LL+IG +C   +   R ++ E+V +IE +
Sbjct:   24 SESEPLVRFKRSVNITKGD--LNSWRTGTDPCNGK---WFGIYCQKGQTVSGIHVTRLGLSGTINIEDLKDLPNLRTIRLDNNLLSGPLPPFFKLPGLKSLLLSNNSFSGEIADDFFKETPQLKRVFLDNNRLSGKIPASLMQLAGLEELHMQGNQFTGEIPPLTDGNKVLKSLDLSNNDLEGEIPITISDRKNLEMKFEGNQRLCGSPLNIECDE-------------------KPSSTGSGNEKNNTAKAIFMVILFLLIFLFVVAIITRWKKKRQPEFRMLGKDHLSDQESVEVRVPDSIKKPIDSSKKRSNAEGSSKKGSSHNGKGAGGGPG---SGMGDIIMVNSEKGSFGLPDLMKAAAEVLGNGSLGSAYKAVMANGLSVVVKRIRDMNKLAREAFDTEMQRFGKLRHPNVLTPLAYHYRREEKLVVSEYMPKSSLLYVLHGDRGVYHSELTWATRLKIIQGVARGMDFLHEEFASYDLPHGNLKSSNVLLSETYEPLISDYAFLPLLQPNNASQALFAFKSPEFVQNQQVSPKSDVYCLGIIVLEVMTGKFPSQYLNTG-KGGTDIVEWVQSSIAQHKEEELIDPEIASNTDSIKQMVELLRIGAACIASNPNERQNMKEIVRRIERV 631          

Query:  115 TDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSL-TTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQR--------SELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKR-ADQGKLSFVREDRQRFDLHDLLRASAEILG-----------SGTFGASYKALIMTDA-VVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNS----RGELLKLLKIGVSCCEEDVERRLDLNEVVEKI 1923
            +++LLKFKK+L   + T+ L +W P+  PC G +  W+G+LC   +V GLQ+E +GL GK+D+ PL  LP L+T+S MNN   G +P+  +   L+SLY+S N FSG IP D FE M  L+K +L+NN FSG IP SL TTLP + ++ LE N+F G IP+F Q  L  +++S N+L G +P  L K D   FAGN  LCG      C                            GT K  +                       F   +K+R        SE D ++  D+  + T    +S    +S  +    K  A    L  V +++  F L DL++A+A +LG           SG  G++YKA++     VVVKR   MN V  + F + +R+LG L H+N+L  +AY++R++EKLLV +FV   +L   LHG+H      LDWP+RL+II+GI+RG+ YL+  L  L +PHG+LKSSN+ L E+ EPL++++ L  +IN +     ++A+KSPE  +   ++ K+DV+ FG+++LE+LTGKFP  Y   +    A+LV W+   +++    ++    +            E+  +L+IGV C  ED ++R ++ EVV+++
Sbjct:   25 SESLLKFKKSL---NNTKSLDSWTPESEPC-GASQRWIGLLCNKNSVFGLQIEQMGLSGKVDVAPLKDLPSLRTISIMNNSFSGDIPEFNRLTALKSLYISGNRFSGNIPSDYFETMVSLKKAWLSNNHFSGLIPISLATTLPNLIELRLENNQFIGSIPNFTQTTLAIVDLSNNQLTGEIPPGLLKFDAKTFAGNSGLCGAKLSTPCPQPKNSTASITIE---------------GTMKDANKSKYFLAFSTLGVLLIVVLVSLAFRKKKKKRRRKKARRTSEQDNSD--DQQIQVTVEGSNSSRQSRSSRSGELNKGVAGTSDLVMVNKEKGVFRLSDLMKAAAHVLGNPGGGSNRPRSSGGVGSAYKAVLSNGVTVVVKRVTVMNQVSVDVFDKEIRKLGSLQHKNVLTPLAYHFRQDEKLLVFEFVPNLNLLHRLHGDHEEFQ--LDWPSRLKIIQGIARGMWYLHRELGFLNLPHGNLKSSNIFLAEDGEPLISEFGLQKLINPDAQSQSLVAFKSPEADRDGTVSAKSDVFSFGVVVLEILTGKFPSQYAGLNRAGGANLVEWLGSALEQGGWMDLLHPMVVTAAAEDKIMEEEIENVLRIGVRCTREDPDQRPNMTEVVDEL 630          

Query:  922 RKQRSELDGTES------LDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYE--GESDADYRSS--VSSEGDDYTSQVV 2007
            ++Q SE    +S       +E+ +  + A S  + V  +  +   KR DQ KL FVR D++RF L D+LRASAE+LGSG FG+SYKA + +  AVVVKR++ M+N+GREEF++HM+++GRL+H NLLPL+A+YYR+EEKLLV++++  GSLA+ LH N      VLDWP RL+I++G++RGL YLY   P L +PHGHLKSSNVLLD NFEPLL DYAL+PV+N +Q+Q  M+AYK+PE+ Q  R ++++DVW  GI+ILE+LTGKFP NYL+Q   +  +L  WV  + + + T++VFD EM        ++LKLLKIG+ CC+ D+E+R++L+E V++IEE+    G      RSS   +S+GD  +S+ +
Sbjct:  298 QQQHSEKSSQDSKVYRKLANETVQRDSTATSGAISVGGLSPD-EDKRGDQRKLHFVRNDQERFTLQDMLRASAEVLGSGGFGSSYKAALSSGRAVVVKRFRFMSNIGREEFYDHMKKIGRLSHPNLLPLIAFYYRKEEKLLVTNYISNGSLANLLHANRTPGQVVLDWPIRLKIVRGVTRGLAYLYRVFPDLNLPHGHLKSSNVLLDPNFEPLLTDYALVPVVNRDQSQQFMVAYKAPEFTQQDRTSRRSDVWSLGILILEILTGKFPANYLRQGKGADDELAAWVESVARTEWTADVFDKEMKAGKEHEAQMLKLLKIGLRCCDWDIEKRIELHEAVDRIEEVDRDAGGGQESVRSSYVTASDGDHRSSRAM 669          

Query:   58 VAYLSCMVMLPFGSPM--DSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTAN---WVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPP 720
            + Y   +++L F SP+  D   DALLKFK +L   S    L  WD  + PC+G+  +   W GV+C NG+V  L+LEN+ L G+LD++ L  +  LK++SFM N  +G +P  +     L  LYL++N F+GEI  D F GM  L K++L  N FSG+IP SL  LP++ ++ LE N F+G+IP F QK+L  +NV+ N+LEG +P +L  M+ + F+GN  LCG P
Sbjct:    9 IVYSLLLIVLLFVSPIYGDGDADALLKFKSSLVNASS---LGGWDSGEPPCSGDKGSDSKWKGVMCSNGSVFALRLENMSLSGELDVQALGSIRGLKSISFMRNHFEGKIPRGIDGLVSLAHLYLAHNQFTGEIDGDLFSGMKALLKVHLEGNRFSGEIPESLGKLPKLTELNLEDNMFTGKIPAFKQKNLVTVNVANNQLEGRIPLTLGLMNITFFSGNKGLCGAP 232          

Query:   31 TPA-SFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKK-NPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRS---------------ELDGTESLDESSKYTAAAGS-SQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALI-MTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQ-AQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEM---GRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESD 1950
            TP+ S +++F + L   + LP    + +   ALL F+  +  G +T +   WD K+ +PCN     W GVLC  G V  L+L    L G +       L  L+TLS   N L G LP DL     LR LYL  N FSGEIP+  F   +L+R L LA N FSG+I S    L R+  + LE NK SG + D +   L + NVS N L G +P+SL+K D  +F G   LCG P     N                        +     KK SG                     M L  +K                  E+ G ++  E+ +  +     S   VK+VE N    +    KL F     + FDL DLLRASAE+LG GTFG +YKA++     V VKR K +    RE F E +  +G + HENL+PL AYYY  +EKLLV DF+  GSL++ LHGN  +  P L+W  R  I  G +RGL YL+S  P  +  HG++KSSN+LL  + +  ++D+ L  +++      +    Y++PE    RR+++K DV+ FG+++LE+LTGK P N +    +   DL  WV+ + +E+  +EVFD E+     V +   E+ ++L++G+ C E+  ++R  + EVV +I+EL +  +D
Sbjct:    6 TPSMSNLSIFFSILLLSLPLPSIGDLAADKSALLSFRSAV--GGRTLL---WDVKQTSPCN-----WTGVLCDGGRVTALRLPGETLSGHIPEGIFGNLTQLRTLSLRLNGLTGSLPLDLGSCSDLRRLYLQGNRFSGEIPEVLFSLSNLVR-LNLAENEFSGEISSGFKNLTRLKTLYLENNKLSGSLLD-LDLSLDQFNVSNNLLNGSIPKSLQKFDSDSFVGTS-LCGKPLVVCSNEGTVPSQPISVGNIPGTVEGS---EEKKKRKKLSGGAIAGIVIGCVVGLSLIVMILMVLFRKKGNERTRAIDLATIKHHEVEIPGEKAAVEAPENRSYVNEYSPSAVKAVEVNSSGMK----KLVFFGNATKVFDLEDLLRASAEVLGKGTFGTAYKAVLDAVTLVAVKRLKDVTMADRE-FKEKIEVVGAMDHENLVPLRAYYYSGDEKLLVYDFMPMGSLSALLHGNKGAGRPPLNWEVRSGIALGAARGLDYLHSQDP--LSSHGNVKSSNILLTNSHDARVSDFGLAQLVSASSTTPNRATGYRAPEVTDPRRVSQKADVYSFGVVLLELLTGKAPSNSVMN--EEGMDLARWVHSVAREEWRNEVFDSELMSIETVVSVEEEMAEMLQLGIDCTEQHPDKRPVMVEVVRRIQELRQSGAD 644          

Query:   34 PASFITLFVAYLSCMVM-LPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKK-NPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRK---------------QRSELDG-TESLDESSKYT---AAAGSSQMDVKSVETN-PHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNV--GREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQ-HLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELL-KLLKIGVSCCEEDVERRLDLNEVVEKIEEL--YEGESDAD 1956
            P S + +   +LS +++ LP  S  D   D          +G +T     W+ K+ +PCN     W GV C +  V  L+L  + L G +       L  L+TLS   N L G LP DL     LR LYL  N FSGEIP+  F   HL+R L LA+N+F+G+I S  T L ++  + LE N+ SG IPD +   L + NVS N L G +P++L++ +  +F     LCG P +  C P                       +      K SG                     M L  +K               Q  E+ G  E++D  + Y+   AAA +   + K+ E N P  K     KL F     + FDL DLLRASAE+LG GTFG +YKA++  DAV V   K++ +V    +EF E +  +G + HENL+PL AYY+ R+EKLLV DF+  GSL++ LHGN  +    L+W  R RI  G +RGL YL+S   S    HG++KSSN+LL ++ +  ++D+ L  ++       +    Y++PE    +R+++K DV+ FG+++LE++TGK P N +    +   DL  WV  + +++   EVFD E+  +     E++ +++++G+ C  +  ++R +++EVV K+E L  Y G    +
Sbjct:    7 PNSSMAILSVFLSLLLLSLPLPSTQDLNADRTALLSLRSAVGGRT---FRWNIKQTSPCN-----WAGVKCESNRVTALRLPGVALSGDIPEGIFGNLTQLRTLSLRLNALSGSLPKDLSTSSNLRHLYLQGNRFSGEIPEVLFSLSHLVR-LNLASNSFTGEISSGFTNLTKLKTLFLENNQLSGSIPD-LDLPLVQFNVSNNSLNGSIPKNLQRFESDSFL-QTSLCGKPLK-LC-PDEETVPSQPTSGGNRTPPSVEGSEEKKKKNKLSGGAIAGIVIGCVVGFALIVLILMVLCRKKSNKRSRAVDISTIKQQEPEIPGDKEAVDNGNVYSVSAAAAAAMTGNGKASEGNGPATK-----KLVFFGNATKVFDLEDLLRASAEVLGKGTFGTAYKAVL--DAVTVVAVKRLKDVMMADKEFKEKIELVGAMDHENLVPLRAYYFSRDEKLLVYDFMPMGSLSALLHGNRGAGRSPLNWDVRSRIAIGAARGLDYLHSQGTS--TSHGNIKSSNILLTKSHDAKVSDFGLAQLVGSSATNPNRATGYRAPEVTDPKRVSQKGDVYSFGVVLLELITGKAPSNSVMN--EEGVDLPRWVKSVARDEWRREVFDSELLSLATDEEEMMAEMVQLGLECTSQHPDQRPEMSEVVRKMENLRPYSGSDQVN 652          

Query:  181 WDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQ------------MDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVV-VKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRV-GNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            W+    PC      W GV C +G V  L+L  +GL G L +  +  L  L+TLSF  N L+GPLP D      LR LYL  N FSGEIP   F   +++R + LA N F G+IP ++ +  R+  + L+ N+ +G IP+   K L++ NVS N+L G +P  L  M  + F GN  LCG P   AC  +                    T    G S K S                        L  +K++ ++  + S++ +   T++A  ++                 V  NP     D   L+F  +    FDL  LL+ASAE+LG GTFG+SYKA      VV VKR + +  V  +EF E ++ LG ++H NL+ L+AYY+ R+EKL+V +++  GSL++ LHGN  S    L+W TR  I  G +R ++YL+S        HG++KSSN+LL E+FE  ++DY L P+I+     + +  Y++PE    R+I++K DV+ FG++ILE+LTGK P +  +Q ++   DL  WV+ + +++  S+VFD E+ R   +S   +++LL IG+SC  +  + R  + EV   IEE+
Sbjct:   46 WNLTAPPCT-----WGGVQCESGRVTALRLPGVGLSGPLPIA-IGNLTKLETLSFRFNALNGPLPPDFANLTLLRYLYLQGNAFSGEIPSFLFTLPNIIR-INLAQNNFLGRIPDNVNSATRLATLYLQDNQLTGPIPEIKIK-LQQFNVSSNQLNGSIPDPLSGMPKTAFLGN-LLCGKPLD-ACPVNGTGNGTV-------------TPGGKGKSDKLSAGAIVGIVIGCFVLLLVLFLIVFCLCRKKKKEQVVQSRSIEAAPVPTSSAAVAKESNGPPAVVANGASENGVSKNPAAVSKD---LTFFVKSFGEFDLDGLLKASAEVLGKGTFGSSYKASFDHGLVVAVKRLRDV-VVPEKEFREKLQVLGSISHANLVTLIAYYFSRDEKLVVFEYMSRGSLSALLHGNKGSGRSPLNWETRANIALGAARAISYLHSR--DATTSHGNIKSSNILLSESFEAKVSDYCLAPMISPTSTPNRIDGYRAPEVTDARKISQKADVYSFGVLILELLTGKSPTH--QQLHEEGVDLPRWVSSITEQQSPSDVFDPELTRYQSDSNENMIRLLNIGISCTTQYPDSRPTMPEVTRLIEEV 613          

Query:    7 MAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESL-DESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYT 1995
            +AK  RA T  S + L +A++  +V+  FGSP    +DALLKFK  L   +    +++W+P   PC    +NWVGVLC NG++RGLQLE++ L G +DL+ LA LP  +TLS M+N  DGPLPD KK  KL++LYLS N FSG+IPD+ FEGM  L++LYLANN  +GKIPSSL TL ++ ++ LEGN+F GQIP+F QK +K +NV+ NELEGP+P++L ++ P +FAGN  LCGPP  G C P                     T  S G  KK S                     F+  + +K +S +  T S  +E+S    A+    +  +  ET+ H K+AD GKL+F+++D ++FDL DLL ASAE+LGSGTFG+SYKA+++   VVVKRY+ M+NVGREEFHEHMRRLGRL H NLLPL AYY RR+EKLLV++F E GSLASHLHGNH+ +   L W  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLD++FEPLL DYAL PV+N E A   MMAYKSPEYAQ  R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL  WVN M+KEKRTSEVFD E+     S+GE++KLLKIG+SCCEEDVERRLD+ EVVEKI+ L EG+ D +      SEG+ Y+
Sbjct:    7 VAKFARATT--SSLVLVLAFVLSIVVTSFGSP---DSDALLKFKDQL---ANNGAINSWNPSVKPCEWERSNWVGVLCLNGSIRGLQLEHMALSGDIDLDALAPLPSFRTLSLMDNNFDGPLPDFKKLGKLKALYLSNNRFSGDIPDNAFEGMGSLKRLYLANNLLTGKIPSSLATLSKLMELKLEGNQFQGQIPNFQQKSMKTVNVASNELEGPIPEALSRLSPHSFAGNKGLCGPPL-GPCIPSPPS-----------------TPKSNG--KKFSILYIVIIILIVLLMLAAIAFAFLLFSRKKCKSRIQRTASSPEENSNKMVASYYRDVHRELSETSSHAKKADHGKLTFLKDDIEKFDLQDLLTASAEVLGSGTFGSSYKAVVVGQPVVVKRYRHMSNVGREEFHEHMRRLGRLKHPNLLPLAAYYNRRDEKLLVTEFAENGSLASHLHGNHSPEEDGLHWHIRLKIVKGVARGLAFLYNELP-IIAPHGHLKSSNVLLDDSFEPLLTDYALRPVVNPEHAHMFMMAYKSPEYAQQSRTSNKTDIWSFGILILEMLTGKFPENYLTPCYNSDADLATWVNNMVKEKRTSEVFDKEIVGTKYSKGEMIKLLKIGLSCCEEDVERRLDIKEVVEKIDVLKEGDEDEEL---YGSEGNAYS 638          

Query:    7 MAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEE 1929
            +A L RA T +S + L +A++  +V+  FGSP    +DALLKFK+ L      E +SNW+   NPC  + +NWVGVLCFNG + GLQLE++GL G +DL+ LA LP  +TLS M+N  DGPLPD KK  KL++LYLS N FSG+IPD  FEGM  L++L+LANN  +GKI SSL  LP++ ++ L+GN+F GQIP+F QK +K  NV+ NELEGP+P++L ++ P++FAGN  LCGPP  G C P                   K  G      KK S                     F+  + ++ +       S  E+S    ++    +  +  ETN H +  D GKLSF+++D ++FDL DLLRASAE+LGSGT+G+SYKA++    VVVKRY+ MNNV REEFHEHMRR+GRL H NLLPL AYYYRR+EKLLV+ F E GSLASHLHGNH+ +   LDW  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLDE+FEPLL DYAL PVIN E A   MMAYKSPEYAQH R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL  WVN M+KEKRTSEVFD EM    NS+GE++KLLKIG+SCCE++VERR D+ E +  + E
Sbjct:    5 VAMLARATT-SSLVLLVLAFVLSIVVTSFGSP---DSDALLKFKEQLV---NNEGISNWNVSVNPCERDRSNWVGVLCFNGGIWGLQLEHMGLAGNIDLDALAPLPSFRTLSLMDNNFDGPLPDFKKLGKLKALYLSNNRFSGDIPDKAFEGMGSLKRLFLANNLLTGKIASSLAILPKLTELKLDGNQFEGQIPNFQQKGMKTANVANNELEGPIPEALSRLSPNSFAGNKGLCGPPL-GPCIPSPPSTP-------------KAHG------KKFSILYIVIIILIVLLILAAIAFAFLLFSRKESKRRTQRRAS--ENSNRIMSSYYRDVHREMPETNSHSRITDHGKLSFLKDDIEKFDLQDLLRASAEVLGSGTYGSSYKAVVGGQPVVVKRYRHMNNVEREEFHEHMRRIGRLKHPNLLPLAAYYYRRDEKLLVTVFAENGSLASHLHGNHSLEEDGLDWRIRLKIVKGVARGLAFLYNQLP-IIAPHGHLKSSNVLLDESFEPLLTDYALRPVINPEHAHVFMMAYKSPEYAQHGRSSNKTDIWSFGILILEILTGKFPENYLTPGYNSDADLATWVNNMVKEKRTSEVFDKEMLGTKNSKGEMIKLLKIGLSCCEQEVERRSDIKEGMHAVLE 615          

Query:   40 SFITLFVAYLSCMVMLPFGSPMDST-TDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTA-NWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESL-----DESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAV-VVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDS-KADLVNWVNGMIKEKRTSEVFDVEM-----GRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGD 1986
            SF+ +F+     ++ L F + +  T ++ LLKFK +L   S    LS+W  K  PC  N A NW GV+C +G + GLQLEN+GL GK+D+E L  LP LKTLS MNN  DGP+P+ KK   LR+LYLS NHFSG IP D F+GM  L+K+YLA N F+G IPSSL  LP++ D+ LEGN+F+GQ+PD  Q +L   +VS N LEGP+P  L KMD S+F+GN  LCGPP +  CN                      T +S   SKKP                      F+FL  + QR      E+          K T     +Q    S + +   K+ +  KLSFVR+DR++FDL DLL+ASAEILGSG FG+SYKA + +  + VVKR+KQMNNVGREEF EHMRRLGRL H NLLPLVAYYYR+EEKLL++DFVE GSLA HLHG+     P LDWP+RL+I+KG+ RGL YLY  LP+++  HGHLKSSNVLL ++ EPLL DY L+PVIN E AQ LM+AYKSPEY  H RITKKTDVW  GI+ILE+L+ K P N++ Q   S + DL NWVN +  E+ T+ V D +M      + G    E++KLLKIG+SCCE DVE+R+DL E VE+IEE+ E +SD D+ SS +SEGD
Sbjct:    8 SFVLVFL-----LLSLHFVASLGLTDSEILLKFKGSL---SNASALSDWSDKTTPCTKNNATNWAGVICVDGILWGLQLENMGLAGKIDMETLQALPDLKTLSIMNNNFDGPMPEFKKIVSLRALYLSNNHFSGVIPLDAFDGMLKLKKVYLAQNEFTGAIPSSLIALPKLLDLRLEGNQFTGQLPDLTQ-NLLSFSVSNNALEGPIPAGLSKMDSSSFSGNKGLCGPPLK-ECN----------------------TINSNSDSKKPPVLLIVIIAAVVGLLLGAIVAAFLFLRRQSQRQPSASIEAPPPPIPSNLKKKTGFKEENQSPSSSPDHSVGSKKGEPPKLSFVRDDREKFDLPDLLKASAEILGSGCFGSSYKAALNSGTMMVVKRFKQMNNVGREEFQEHMRRLGRLKHSNLLPLVAYYYRKEEKLLITDFVEKGSLAVHLHGHQALGQPSLDWPSRLKIVKGVVRGLAYLYKDLPNIIAAHGHLKSSNVLLTQSNEPLLTDYGLVPVINQENAQELMVAYKSPEYLHHGRITKKTDVWSLGILILEILSAKLPANFVPQGKGSEEEDLANWVNSVPHEEWTNVVIDKDMTNGPTKQNGGGESEVIKLLKIGLSCCEADVEKRIDLKEAVERIEEIKERDSDDDFFSSYASEGD 638          

Query:   40 SFITLFVAYLSCMVMLPFGSPMDST-TDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTA-NWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCG---TSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRS----ELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAV-VVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDS-KADLVNWVNGMIKEKRTSEVFDVEMGRV-----GNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQ 2001
            SF+ +F+     +V L F + +  T ++ LLKFK +L   +   VLS+W  K  PC  N A NWVGV+C  G++ GLQLEN+GL GK+D+E L  LP LKT S MNN  DGP+P+ KK   LRS+YLS NHFSG IP D F+G+  L+K+YLA N F+G IPSSL  LP++  + LEGN+F+G++PDF   +L+  +VS N LEGP+P  L KMD S+F+GN  LCGPP    CN                      T D+ G    SKK                       F+FL  R++++    E           K T     +Q    S + +   ++ +  KLSFVR+DR++FDL DLL+ASAEILGSG FG+SYKA + +  + VVKR+KQMNNVG+EEF EHMRRLGRL H NLLPLVAYYYR+EEKLL++DFVE GSLA+HLHG+     P L WP+RL+I+KG++RGL YLY  LP+++  HGHLKSSNVLL ++ EP+L DY L+PVIN E AQ LM+AYKSPEY  H RITKKTDVW  GI+I+E+LTGK P N++ Q   S + DL +WVN +  E+  + V D +M  V     G    E++KLLKIG+SCCE DVE+RLDL E VE+IEE+ E +SD D+ SS +SEGD  +S+
Sbjct:   25 SFVLVFL-----LVSLHFVASLGLTDSEILLKFKGSL---TNASVLSDWSDKTTPCTKNNATNWVGVICVEGSLWGLQLENMGLAGKIDVEILKSLPDLKTFSIMNNNFDGPMPEFKKMVTLRSIYLSNNHFSGVIPPDAFDGILKLKKVYLAQNEFTGAIPSSLVALPKLLVLRLEGNQFTGKLPDFTH-NLQSFSVSNNALEGPIPTGLSKMDLSSFSGNKGLCGPPLN-ECN----------------------TTDNDGHDSDSKKTPVLLIVILAAAVGLLIGAIVAAFLFLRRRQRQASGSIEAPPPPIPSNLKKKTGFKEENQSPSSSPDHSVGSRKGEGPKLSFVRDDREKFDLPDLLKASAEILGSGCFGSSYKAALSSGTMMVVKRFKQMNNVGKEEFQEHMRRLGRLKHSNLLPLVAYYYRKEEKLLITDFVEKGSLAAHLHGHQALGQPSLGWPSRLKIVKGVARGLAYLYKDLPNIIAAHGHLKSSNVLLTQSNEPMLTDYGLVPVINQENAQELMVAYKSPEYLHHGRITKKTDVWSLGILIVEILTGKLPANFVPQGKGSEQQDLASWVNSVPYEEWINVVLDKDMTNVSTKPNGGGESEVMKLLKIGLSCCEADVEKRLDLKEAVERIEEIKEKDSDDDFFSSYASEGDMKSSR 662          

Query:  115 TDA--LLKFKKTLQLGSKTEVLSNWDPKK-NPCNGNTANWVGVLCFNGN-VRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGK-LSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESD-ADYRSSVSSEGDDYTSQVV 2007
            TDA  L+ FK +L   S   +L +W+     PC G T NWVG+ C N + +  L LEN+GL+G +D++ L QLP L+TLSFMNN  +GP+P++KK   LR+LYLS N+FSG+I  D F+GM  L+++YLA+N F+G+IP SL  + ++  + LEGN+F G +PDF Q++L   N + N  +G +P SL    PS+FAGN  LCG P                               +C +S+K +                     F  + +R+ ++     +  D   K+    G  + + +S +     K  D G+ L FVR DR RFDL DLLRASAE+LGSGTFG+SYKA+++   A+VVKR++ M+NVG+E FHEHMR+LG L+H NLLPLVAYYYR+EEKLLVSDFV  GSLASHLHG  +   P +DWPTRLRIIKG+++GL YLY   P+L +PHGHLKSSNVLLD+ FEPLL DYAL+PV+N + +Q +M+AYKSPE +Q  R  +KTDVW  GI+ILE+LTGKFPENYL Q     ADL  WVN +++E+ T EVFD++M R  N  GE+LKLLKIG+ CCE ++ERR DL   V KIEEL E ++D  D+ +S +SEG+ Y+S+ V
Sbjct:   32 TDAEILVNFKNSLSTNS---LLYDWNASGIPPCTGGTDNWVGLRCNNDSTIDKLLLENMGLKGTIDIDILMQLPTLRTLSFMNNSFEGPMPEVKKLSSLRNLYLSNNNFSGKIDKDAFDGMSSLKEVYLAHNEFTGEIPRSLVLVQKLTKLSLEGNQFDGNLPDFPQENLTVFNAAGNNFKGQIPTSLADFSPSSFAGNQGLCGKPLP-----------------------------ACKSSRKKT--VVIIVVVVVSVVALSAIVVFACIRSRQNKT----LKFKDTKKKF----GDDKKEAQSSDQFGDGKMGDSGQNLHFVRYDRNRFDLQDLLRASAEVLGSGTFGSSYKAVLLDGPAMVVKRFRHMSNVGKEGFHEHMRKLGTLSHPNLLPLVAYYYRKEEKLLVSDFVGNGSLASHLHGKRSPGKPWIDWPTRLRIIKGVAKGLAYLYKEFPTLALPHGHLKSSNVLLDDTFEPLLTDYALVPVVNKDHSQQVMVAYKSPECSQSDRPNRKTDVWSLGILILEILTGKFPENYLTQGKGGDADLATWVNSVVREEWTGEVFDMDMMRTKNCEGEMLKLLKIGMCCCEWNLERRWDLKVAVAKIEELKERDNDNDDFSNSYASEGEVYSSRAV 627          

Query:  115 TDA--LLKFKKTLQLGSKTEVLSNWDPKKNP-CNGNTANWVGVLCF-NGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESD-ADYRSSVSSE 1980
            TDA  L+ FK +L   S   +LSNW+   NP CNG+T NWVG+ C  +G +  LQLEN+GL G ++++ L QL  L+TLSFMNN L+G +P +KK   L++L+LS N FSG+I +D F+GM+ LR+++LA+N F+G IP SL +  ++  + LEGN+  G++P F Q++L   N + N  EG +P SL    PS+F GN  LCG P                               +C +SKK                        +     K       T   + S K  A  G  + +++S +     K  D G+L FVR DR RFDL DLL+ASAE+LGSGT G+SYK ++    ++VVKR++ M+NVG EEFHEHMR+LG L+H NLLPLVAYYYR+EEKLLVSD +E GSLAS LH       P LDWPTRL+I+KG++RGL YLY   P+L +PHGHLKSSNVLLD+ FEPLL DYAL+P++N + AQ +M+AYKSPE+    R T+KTDVW  GI+ILE+LTGKFPENYL Q     ADL  WVN +++E+ T EVFD+++ R  N   E+LKLLK G+ CCE ++E R DL E V KIE+L E ++D  D+ +S +SE
Sbjct:   16 TDAEILVNFKNSLSTNS---LLSNWNVSGNPPCNGSTNNWVGLRCNGDGTIDKLQLENMGLTGTINIDILTQLSKLRTLSFMNNSLEGSMPQVKKLGPLKNLFLSNNSFSGKIAEDAFDGMNSLREVHLAHNEFTGGIPRSLVSAQKLTKLSLEGNQLDGKLPGFPQENLTVFNAADNNFEGQIPASLAHFSPSSFTGNKGLCGKPLP-----------------------------ACKSSKKKIMMIIVVTVVAVVALSAIVAFSCICCRTAK-------TPKFNYSKKKIAMNGVGKKEIQSSDQFGDAKTVDNGQLHFVRYDRGRFDLQDLLKASAEVLGSGTLGSSYKTVLSDGPSMVVKRFRHMSNVGNEEFHEHMRKLGTLSHPNLLPLVAYYYRKEEKLLVSDLIENGSLASRLHAKRAPGKPWLDWPTRLKIVKGVARGLVYLYKEFPTLALPHGHLKSSNVLLDDTFEPLLTDYALVPLVNRDHAQQVMVAYKSPEFTHSDRTTRKTDVWSLGILILEILTGKFPENYLMQGRGGGADLATWVNSVVREEWTGEVFDMDIMRTKNCEKEMLKLLKTGMCCCEWNMENRWDLKEAVAKIEDLKERDNDNDDFSNSYASE 604          

Query:  619 LNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFL--NNRKQRSELDGTESL-DESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            +NV+ NELEGP+P++L ++ P +FAGN  LCGPP  G C P                        S  ++ K +G                    F FL  + +K +S +  T S  +E+S    A+    +  +  ET+ H K+AD GKL+F+++D ++FDL DLL ASAE+LGSGTFG+SYKA+++   VVVKRY+ M+NVGREEFHEHMRRLGRL H NLLPL AYY RR+EK LV++F E GSLASHLHGNH+ +   L W  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLDE+FEPLL DYAL PV+N E A   MMAYKSPEYAQ  R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL   VN M+KEKRTSEVFD E+     S+GE++KLLKIG+SCCEEDVERRLD+ EVVEKI+ L EG+ D +   S
Sbjct:   35 INVASNELEGPIPEALSRLSPHSFAGNKGLCGPPL-GPCIP------------------------SPPSTPKSNGKKFSILYIVLIVLLMLAAIAFAFLLVSRKKCKSRIQRTASSPEENSNKMVASYYRDVHRELSETSSHAKKADHGKLTFLKDDIEKFDLQDLLTASAEVLGSGTFGSSYKAVVVGQPVVVKRYRHMSNVGREEFHEHMRRLGRLKHPNLLPLAAYYNRRDEKHLVTEFAENGSLASHLHGNHSPEEDGLHWHIRLKIVKGVARGLAFLYNELP-IIAPHGHLKSSNVLLDESFEPLLTDYALRPVVNPEHAHMFMMAYKSPEYAQQSRTSNKTDIWSFGILILEMLTGKFPENYLTPCYNSDADLATSVNNMVKEKRTSEVFDKEIVGTKYSKGEMIKLLKIGLSCCEEDVERRLDIKEVVEKIDVLKEGDEDEELYGS 461          

Query: 1069 VREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYT 1995
            +++D ++FDL DLL ASAE+LGSGTFG+SYKA+++   VVVKRY+ M+NVGREEFHEHMRRLGRL H NLLPL AYY RR+EKLLV++F E GSLASHLHGNH+ +   L W  RL+I+KG++RGL +LY+ LP ++ PHGHLKSSNVLLDE+FEPLL DYAL PV+N E A   MMAYKSPEYAQ  R + KTD+W FGI+ILE+LTGKFPENYL   Y+S ADL  WVN M+KEKRTSEVFD E+     S+GE++KLLKIG+SCCEEDVERRLD+ EVVEKI+ L EG+ D +      SEG+ Y+
Sbjct:    2 LKDDIEKFDLQDLLTASAEVLGSGTFGSSYKAVVVGQPVVVKRYRHMSNVGREEFHEHMRRLGRLKHPNLLPLAAYYNRRDEKLLVTEFAENGSLASHLHGNHSPEEDGLHWHIRLKIVKGVARGLAFLYNELP-IIAPHGHLKSSNVLLDESFEPLLTDYALRPVVNPEHAHMFMMAYKSPEYAQQSRTSNKTDIWSFGILILEMLTGKFPENYLTPCYNSDADLATWVNNMVKEKRTSEVFDKEIVGTKYSKGEMIKLLKIGLSCCEEDVERRLDIKEVVEKIDVLKEGDEDEEL---YGSEGNAYS 306          

Query:  109 STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVK---------------SVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDA-VVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRS 1965
            S ++ALL+ KK+    +    LS+W     PCN  T +W G+LCFNG V GLQLEN+GL G +D++ LA +  L++LSF  N   G +P+L +   L+++YL  N FSGEIP D F  M  L+K++L++N F+G IP SL  LPR+ ++ LE N+FSG IP   Q  L   NVS N LEG +P +L   + S+F GN  LCG  F   C                             +S+ P+G                    F     R +R + D  + ++ SS   AAA + ++ V                S     +  R   G+L  V  ++  F L DL++ASAE+LG+G  G+ YKA +   A VVVKR ++MN + +++F   +R+LGRL H N+L  +A+ YR +EKLLV +++  GSL   LHG+  +    L+W  RL+I++GI++GL YL++ L S  +PHG+LKSSNV L  + EPLL+++ L P+I+       +  YK+PE AQ+  ++   DV+C GII+LE+LTGKFP  YL ++     D+V WV   + + R +++ D E+    NS G++ +LL IG +C + + ++RLD+ + ++ I+ +   +S+ + R+
Sbjct:   28 SDSEALLRLKKSF---TNAGALSSWISGSVPCNRQT-HWNGLLCFNGIVTGLQLENMGLSGTIDVDALATIQGLRSLSFARNSFTGAIPELNRLGNLKAIYLRGNQFSGEIPSDFFSKMKSLKKVWLSDNKFTGGIPPSLAELPRLSELHLENNQFSGTIPSIDQPTLMSFNVSNNMLEGEIPPNLAIFNYSSFDGNDHLCGDRFGRGCENTMQT-----------------------SSESPTGTVAGAVTLAVLLLSITALIIF-----RMRRRDKD-FDVIENSSNGNAAAAALEVQVSLSNRPKGVDATKKMGSSRKGSNNGRGGVGELVIVNNEKGVFGLPDLMKASAEVLGNGGMGSLYKAQMANGAMVVVKRTREMNTLSKDQFDAEIRKLGRLHHTNILTPLAFLYRPDEKLLVYEYMPKGSLLYLLHGDRGTSHAELNWFVRLKIVQGIAKGLGYLHTKLASSPLPHGNLKSSNVFLSNDNEPLLSEFGLSPLISPPMLAQALFGYKAPEAAQY-GVSPMCDVYCLGIIVLEILTGKFPSQYLNKA-KGGTDVVQWVESAVSDGRETDLLDPEIASSTNSLGQMRQLLGIGAACVKRNPQQRLDITDAIQMIQGIKLEDSNHEGRT 627          

Query:  109 STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESS------KYTAAAGSSQMDVKSVETNPHPK----RADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVV-KRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESD 1950
            S +++L++ KK+    +    +S+W P   PCN  T +W GV+CFNG V  LQLEN+GL G +D++ LA +  L++LSF  N   G +P L +   L+++YL  N FSGEIP D F  M  L+K+++++N FSG IPSSL  L R+ ++ LE N+FSG IP   Q  L   NVS N+L+G +P  L + + S+F GN  LCG      C                     +      G+  K +                      +     ++  + D  ES    +      + + +    +M+V     + H      R   G+L  V  ++  F L DL++ASAE+LG+G  G+SYK  +    VVV KR ++MN + + +F+  +R+LGRL H N+L  +A++YR +EKLL+ DFV  GSL   LHG+       L W  RL+I++GI++GL YL++ L    +PHG+LKSSNV L  + EPLL+++ L P+I+       +  Y++PE A+   ++ K DV+C GIIILE+L+GK P  YL  +     D+V+WV   I + R ++  D E+    NS  ++ +L  IG +C + + E+RLD+ + ++ I+E+   + D
Sbjct:   28 SESESLIRLKKSF---TNAGAISSWLPGSVPCNKQT-HWRGVVCFNGIVTVLQLENMGLSGTIDVDALANMQGLRSLSFAYNYFTGTIPALNRLGYLKAIYLRGNQFSGEIPSDFFLKMKSLKKVWISDNNFSGGIPSSLAELSRLSELHLENNQFSGTIPSIDQPTLMSFNVSNNKLDGEIPPKLARFNSSSFRGNDGLCGQKIGKGCELQGSSEPPTDVGVDANMMVSE------GSDNKRNSVTKTVAGLVTLAVLLVSIIAVVIFRMWRRGKDFDAIESRSSGNAAALEVQVSLSNRPKEMEVAKKMGSGHKGSNNGRGVVGELVIVNNEKSVFGLPDLMKASAEVLGNGVLGSSYKTQMANGVVVVVKRMREMNTLSKSQFNAEIRKLGRLHHPNILTPLAFHYRPDEKLLIYDFVPKGSLLYLLHGDRGPSHAELSWSVRLKIVQGIAKGLGYLHTELAPSNLPHGNLKSSNVFLSNDNEPLLSEFGLSPLISPPMLAQALFGYEAPEAAEF-GVSPKCDVYCLGIIILEILSGKIPSQYLNNARGG-TDVVHWVESAISDGRETDFLDPEIASSKNSLCQMKQLQGIGAACVKRNPEQRLDITQAIQLIQEIKLEDGD 640          

Query:    1 MAMAKLMRAP--TPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPS-GXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDES-SKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQVV 2007
            MAMA+LMRAP  TP  F+ LF+A LSCMVMLPFGSPM +T +AL++FKKTLQLG+++  LS+WDP K+PCNGN  NWVGVLCFNGNVRGLQLENLGLQGKLDLEPL +LPYLKTLSFMNN L GPLPDLK  K LRS+YLSYNHFSGEIPDD FEGM LLRKLYL NN F+GKIPSSLTTLP++FDVGLE NKFSGQIP+F QK LKRLN++ NELEGPVP+SL K+DPS+F+GNGKLCGPP  G C+                    +C+GDSCGTSKKPS G                     +FLN ++Q+SELD  ESLD+S SKYTAA GSSQMDVKSVE  PHPK+ D GKLSFVR+DRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTH NLLPLVAYYYRREEKLLVSDFVE GSLASHLHGNHNSD PVLDWP RLR+IKGI+RGLTYLYS LPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWC GIIILEVLTGKFPENYLKQS+DS+ADL +WVNGMIKEKRTSEVFDVEMG VG+S+GELLKLLKIGV CCEEDVERRLDL EVVEKI+EL EGESD DYRSSVSSEGDDYTSQVV
Sbjct:    7 MAMARLMRAPNPTPTFFVALFIAVLSCMVMLPFGSPMATTAEALMRFKKTLQLGNESATLSSWDPNKDPCNGNKVNWVGVLCFNGNVRGLQLENLGLQGKLDLEPLTRLPYLKTLSFMNNSLAGPLPDLKNLK-LRSVYLSYNHFSGEIPDDAFEGMILLRKLYLGNNQFTGKIPSSLTTLPKIFDVGLEENKFSGQIPEFRQKGLKRLNLANNELEGPVPESLSKLDPSSFSGNGKLCGPPLAGKCSD----PPPPASPPSPSAPPSECSGDSCGTSKKPSSGLKIALIVVSILLLLALIAVILIFLNKKRQQSELDVAESLDDSASKYTAAGGSSQMDVKSVEATPHPKKGDHGKLSFVRDDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHPNLLPLVAYYYRREEKLLVSDFVENGSLASHLHGNHNSDQPVLDWPIRLRVIKGIARGLTYLYSALPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCLGIIILEVLTGKFPENYLKQSFDSRADLASWVNGMIKEKRTSEVFDVEMGGVGSSKGELLKLLKIGVKCCEEDVERRLDLTEVVEKIDELNEGESDGDYRSSVSSEGDDYTSQVV 674          

Query:  109 STTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFN-GNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQK-DLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTE------------SLDESSKYTAAAGSSQMDVKSVETNPHPKRADQG-KLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAV-VVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGES---DADYRSSVSSEGD 1986
            S ++ALLKFK +L+    T+ L+NW     PC G T+NWVG+ C   G V GLQLE +GL G ++++ L  LP L+T+SFM N  DGP+PDL+K   L+++YLS N FSG IP D F GM  L+K++LANN F+G+IP SLT L ++ ++ LE NKF G+IPDF Q       NVS N+LEG +P+ L+K+D S+FAGN  LCG   + AC                              SKKP+                       F+  R+ ++     E            S+    +  A+A  S  ++   E +    +ADQ  KLSFVR+DR+RFD+ DLLRASAE+LGSG FG+SYKA +++  V VVKRYKQMNNVG+E+F EHMRR+GRL H NLLPLVAYYY++EEKLL+SD V+ GSLA HLHG+     P LDW TRL+I+KG+++GL YLY  LPSLV PHGHLKSSNVLL+E++EPLL DY L+PV+N E A  LM+AYKSPE+ Q +RITKKTDVW FG++ILE+LTGK P N+L+    S+ DL +WVN + +++  S+VFD +MG   NS GE+LKLL IG+ CCE +VE+R DL EVVE+IEE+ E ++   D D+ SS +SEGD
Sbjct:   21 SDSEALLKFKDSLK---NTDELTNWKSSSIPCEGATSNWVGIRCDGKGRVWGLQLEKMGLNGDINVDILKDLPDLRTISFMKNNFDGPMPDLRKLTALKTVYLSDNKFSGAIPPDWFAGMPSLKKVHLANNQFTGEIPRSLTGLDKLVELSLENNKFKGKIPDFRQPAGFTTFNVSNNKLEGEIPEGLRKLDASSFAGNEDLCGGTLK-AC-----------------------------PSKKPATWSIVVVVIIVIVALAAIAIAAFFILRRRNKASESSIEDPPPSTATVQNRSVRNEPEQQASAPGSPENLNGREVSGKQNKADQSLKLSFVRDDRERFDMQDLLRASAEVLGSGCFGSSYKAALLSGPVMVVKRYKQMNNVGKEDFQEHMRRIGRLAHPNLLPLVAYYYKKEEKLLISDHVQKGSLAVHLHGHQTVGQPSLDWQTRLKIVKGVAQGLRYLYHELPSLVAPHGHLKSSNVLLNESYEPLLTDYGLIPVVNQEHAHTLMVAYKSPEFMQSKRITKKTDVWGFGVLILEILTGKLPTNFLQHGKASEEDLASWVNSVPQDEWFSQVFDRDMGAGKNSEGEMLKLLNIGLGCCEGEVEKRWDLKEVVERIEEVKERDNNHGDEDFLSSCASEGD 632          

Query:   52 LFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCF-NGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKD--LKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYTSQVV 2007
            L V +    + +   S   S    LLKFK  L   S    L NW+   NPCNG    W G+ C  NGNV GL+L+N+GL G +D++ L+ L  L+++S MNN  +GPLP L K   L  +YLS N F+GE+ D+ FEGM  L+K+YL  N FSGKIP SL  L ++ ++GL+GN+FSG+IP+F Q     K  N+S N  EG +P SL  ++ S F GN  LCG P                                C +SKK                        +F+  R  +S+ +        +++  AA   Q+   + + + + K    G+L FVR+DR  F+L +LLRA AE+LGSG+FG+SYKA +++ ++VVKR++Q+N VG+E+F++HMRRLGRL+H NLLPLVA+YYR+EEKLLV DFV  GSLASHLH       P LDWPTRL IIKG+SRGL YLY   P L VPHGHLKSSNVLLD NF PL+ +YAL+PVIN + AQ  M+AYKSPE++   + +KKTDVW  GI+I E+LTGKFP NYL+Q   + ADL  WVN +++E+ T EVFD  M    N  GE+LKLLKIG+ CCE  VE R D  EVV+KIEEL E +S+ +Y SS +S+GD  +S+ +
Sbjct:   14 LLVLFFLAQLCIFVSSSDPSEIQTLLKFKSFL---SNDTALDNWNNSTNPCNGTANIWAGLYCDKNGNVYGLKLQNMGLMGIIDIDTLSGLSALRSISIMNNNFEGPLPSLNKLGALIGVYLSNNQFTGEMQDNAFEGMSSLKKIYLDGNEFSGKIPKSLAALSKLSELGLQGNQFSGKIPNFAQSPNGWKYFNISNNRFEGRIPASLSNLEASAFTGNLGLCGKPLA-----------------------------PCKSSKKKI-LLIIAIVVVSIAAILCTIVAILFIRRRSAKSKQEARAQKKLKAQHHTAATEVQL---TADEDNYKKAEKGGELYFVRKDRG-FELEELLRAPAEVLGSGSFGSSYKAGLLSGSMVVKRFRQINQVGKEDFYDHMRRLGRLSHPNLLPLVAFYYRKEEKLLVHDFVANGSLASHLHVKREPGQPGLDWPTRLMIIKGVSRGLGYLYKEFPGLTVPHGHLKSSNVLLDHNFNPLIAEYALIPVINRDHAQKFMVAYKSPEFSHMEQTSKKTDVWSLGILIFEMLTGKFPANYLQQGKRANADLAAWVNSVVREEWTGEVFDKNMKGTKNGEGEMLKLLKIGMCCCESSVEGRWDWREVVDKIEELKERDSEEEY-SSYASDGDMGSSRAM 630          

Query:   46 ITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGAC---NPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFM--FLNNRKQRSELD----GTESLDESSKYTAAAGSSQMDVKSVET------------NPHPKRADQGK-------LSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            ++L +  L+ M++L +   + +  +ALLK K++ +     E L++W P   PC  NT  W G++C +G V GL+L  +GL G++D + LA++  L+T+SF NN   GP+P+      ++ LYLS N F+GEIP + F  M  LRKL+L+NN F+G IP SL T+P + ++ LE N FSG IP   Q  L  LN+S N+LEG VP S+ K + S+FAGN  LCG      C    P                          G++ K +G                     +  F+ +R++  E D    G E++ E + +  +   +  ++K  E             N   K ++ GK       L  + E++  F L DL++A+AE+LG+G  G+SYKA++    AVVVKR ++MN +G++ F   MRR G L H N+L  +AY+YR+EEKLL+ +++   SL   LHG+       LDWP RL+II+G ++GL Y+++   S  VPHG+LKSSN+LL  ++EPLL+D+A  P+IN       + AYK+PE A+H R++ K DV+C GIIILE+LTGKFP  YL        D++ WV   I E R SE+ D E+     S GE+ KLL IG +C E +  +RLD+ E V +IE++    SD   R+S
Sbjct:    4 LSLLLLLLASMLLLCWSYSL-AEPEALLKLKESFK---NAEALNSWTPDTAPCARNT-QWAGLICADGIVTGLRLGGMGLAGEIDTKVLAEIKGLRTMSFANNNFSGPMPEFNTLGPVKGLYLSGNQFTGEIPSNFFVKMESLRKLWLSNNKFTGNIPPSLATIPNLLELHLEDNGFSGSIPVINQSTLVSLNMSNNKLEGEVPASMSKFEASSFAGNAGLCGGKLGKECAKPEPPPAASTTPNENNNNNNNNNNDNNGGNGSNSKGNGGSSKVVVAVSVASAVVLVALIVLFFVKSRRKGEEEDFDMPGKENI-EKADHPDSVELNVSEIKQKEVVVDRPSSSKRTGNSSRKGSNNGKGGGGMAELVMLNEEKGVFGLPDLMKAAAEVLGNGGLGSSYKAVMANGFAVVVKRMREMNGMGKDGFDAEMRRFGSLRHWNILTPLAYHYRKEEKLLIYEYIPKSSLLYILHGDRGPSHDELDWPARLKIIQGTAKGLAYIHTEFASCDVPHGNLKSSNILLGPDYEPLLSDFAFGPLINTANVAQALFAYKAPEAAEHGRVSPKCDVYCLGIIILEILTGKFPSLYLNNG-KGGLDVIQWVRSAISEGRESELLDPEISSTKASLGEMEKLLHIGAACTESNPNQRLDMREAVTRIEQVQVLGSDHVPRTS 666          

Query:   64 YLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKN--PCNGNTANWVGVLCFNGN--VRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGAC-----NPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXF----------MFLNNRKQRSE---LDGTESLDES----------SKYTAAAGSSQMDVKSVETNPHP----KRADQGK-----LSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            + S    L    P D   +ALLKFKK+L   ++   L  W P +N  PC    A W G++C  G+  + GL + N+GL GK+D + L  +P L+T++FMNN   G +PD      L+SL LS N FSGEIP D F  M  L+K+YL NN F+GKIP SL  L ++ ++ LE N+F+G IP   Q  L  L++S N+L+GP+P S+ K +P  F GN  LCG P + +C     +P                     T         PS                                +F+  R++R +   + G E LD+           S    + GSS   ++  +T+       K ++ GK     L  V +++  F L DL++A+AE+LG+G  G++YKA++    +VVVKR + MN +GR+ F   MRR GRL H+N+L  +AY+YRREEKLL+S+++  GSL   LHG+       L+WP RL+II+GI+ GL ++++   S  +PHG+LKSSNVLL++++EP+LNDYAL P+IN   A   M A+++PE  + ++ + K+DV+C GI+ILE+LTGKFP  YL        D+V WV   + E+R  E+ D E+    +S  ++++LLKIG  C   D E+RLD+ E + +IEE+
Sbjct:   12 FFSSSPYLSLSLPQDQ--EALLKFKKSL---TRAGALDKWTPDQNSSPCK---AQWTGIVCSKGSNVISGLHISNMGLSGKIDFDALKDIPTLRTINFMNNNFSGSIPDFHTLGALKSLLLSGNGFSGEIPKDYFSHMTSLKKIYLDNNNFTGKIPESLGQLNKLEELHLEKNQFTGPIPKLKQ-GLNSLDLSNNKLQGPIPDSMSKYNPKAFEGNEGLCGVPLKSSCQSPSPSPSPAPSPSPAPTPAPSLSPSPSTPSPSAPPSSPSSSSSDVDSKRTTTIIIIISVILGIMILLLLYVLFVAKRQKRDDDFDVLGKEQLDDHHQRVVEVHVPSSNNRSLGSSNHSLEVHQTSSKKGDSKKGSNHGKNGMNELLMVNDEKGSFGLSDLMKAAAEVLGNGGLGSAYKAVMSNGMSVVVKRMRDMNRLGRDGFDAEMRRFGRLRHKNILTPLAYHYRREEKLLISEYIPKGSLLYLLHGDRGISHSELNWPIRLKIIQGIACGLGFIHTEFASYDLPHGNLKSSNVLLNDDYEPVLNDYALHPLINPNTAAQTMFAFRTPEITESQQTSPKSDVYCLGILILEILTGKFPSQYLTNG-KGGTDVVQWVQSAMAEQREEELLDPEIASDADSVDQMVQLLKIGADCTLSDPEQRLDIREAIRRIEEV 666          

Query:    1 MAMAKLMRAPTPASFITLFVAYLSCMVMLPFGSPMDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCF--NGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQK--DLKRLNVSQNELEGPVPQSL-KKMDPSNFAGNGKLCGPP------FQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQM-DVKSVETNPH------PKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVV-VKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLK------QSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDY 1992
            M  +K +      S + L +A+ S        SP  + T AL +F+  LQ  +   +LSNW    +PC   T++W GV C      V  L L +L L+G LD   LA L  L+ L   NN L+G +  L     L+ LYL+ N  SGEIP  EF  +  L +L L++N   G IP +LT L R+  + L+ N  SG++PD      DLK LN + NEL G +P+ L +K    +F+GN  LCG        F GA +P                       +      +                          L +   R    G+ S+  S      +GSS   D K V  N            D+ KL F  + R++F+L DLLRASAE+LG G+ G  YKA++     + VKR K  N   R+EF ++M  +G++ H N++ L AYYY +EEKLLV D++  GSL S LHGN       LDW TR+ ++ G +RGL  ++    S  VPHG++KSSNVLLD+N    ++D+ L  ++N   A   +  Y++PE A+ +R+++K DV+ FG+++LEVLTG+ P  Y        +  +   DL  WV  ++KE+ T EVFD E+ R  N   EL+ +L +G++C     E+R  + EV + IE         D R   S  G+DY
Sbjct:    1 MKKSKALALVATLSLLLLALAHPSLS-----SSPPHNDTWALTQFR--LQTDTHGYLLSNWTGA-DPC---TSSWTGVRCSISKSRVVALSLPSLNLRGPLDF--LAFLDQLRFLDLHNNRLNGTVSPLTNCTNLKLLYLAGNDLSGEIPP-EFASLRRLLRLDLSDNNLRGPIPRNLTALTRLLTLRLQNNALSGEVPDLSGSLADLKELNFTNNELYGRLPEGLLRKFGDESFSGNEGLCGASPLPACSFTGATSPPSAASAQTVPSNPSQLPQTTSVNEPEKKKSRKGLSPGAIVAIVIANCVAMLVVVSFILAHYCARDR--GSNSIGGSESGKRRSGSSYGGDQKKVYANSGGADSDGTNATDRSKLVFF-DRRKQFELEDLLRASAEMLGKGSLGTVYKAVLDDGCTMAVKRLKDANPCARKEFEQYMDLIGKVKHPNVVRLSAYYYAKEEKLLVYDYLPNGSLHSLLHGNRGPGRIPLDWTTRISLMLGAARGLARIHEEYSSAKVPHGNVKSSNVLLDKNGVACISDFGLSLLLNPVHAIARLGGYRAPEQAEVKRLSQKADVYSFGVLLLEVLTGRAPSQYPSPARPRVEEEEEAVDLPKWVRSVVKEEWTGEVFDQELLRYKNIEEELVAMLHVGLACVVPQPEKRPTMAEVAKMIE---------DIRVERSPLGEDY 663          

Query:  181 WDPKKNPCNGNTANWVGVLCFNGN--VRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAA----GSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMT-DAVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSS 1968
            W+   + C      WVG+ C      V  L+L  +GL G +    L +L  L+ LS  +N L+GP+P D      LRSLYL  N FSGE P      + L R L L++N F+G IP ++T L  +  + LE N+FSG +P     +L+  NVS N+L G +P SL K   S F GN  LCG P   ACNP                   K        SKK S                      +    +++R +         +++  A A     SS+ D+    T      A++ KL F       FDL DLLRASAE+LG G+ G SYKA++     VVVKR K +  V + EF   M  LG++ H+N++PL A+Y+ ++EKLLV D++  GSL++ LHG+  S    LDW  R++I    +RG+ +L+    S  V HG++KSSN+LL    +  ++D+ L P+       + +  Y++PE  + R++T K+DV+ FG+++LE+LTGK P        +   DL  WV  +++E+ T+EVFDVE+ R  N   E+++LL+I ++C     ++R  + EVV  IE++   E+D   R S
Sbjct:   55 WNSSVSACT-----WVGITCDANQSYVSALRLPGVGLVGPVPPNTLGRLSQLRVLSLRSNRLNGPIPSDFSNLTLLRSLYLQGNQFSGEFPPGLTRLVRLTR-LDLSSNNFTGPIPFTVTNLTHLTGLFLENNEFSGSLPSISAGNLRSFNVSNNKLNGSIPASLSKFPDSAFTGNLNLCGKPLT-ACNPFFPAPAPSPSTPPVIPVHKK--------SKKLSTAAIVAIAVGSALALFLLLLVLLLCIRKRRRQQQAKPPKPPVATRSVAVAEAGTSSSKDDITGGSTE-----AERNKLVFFDGGVYSFDLEDLLRASAEVLGKGSVGTSYKAVLEEGTTVVVKRLKDV-VVTKREFEMQMEVLGKIKHDNVVPLRAFYFSKDEKLLVYDYMAAGSLSALLHGSRGSGRTPLDWDNRMKIALSAARGIAHLH---VSGKVVHGNIKSSNILLRPEHDASVSDFGLNPLFGTSTPPNRVAGYRAPEVVETRKVTFKSDVYSFGVLLLELLTGKAPNQ--ASLGEEGIDLPRWVQSVVREEWTAEVFDVELMRYHNIEEEMVQLLQIAMACVSTVPDQRPAMQEVVRMIEDMNRAETDDGLRQS 632          

Query:  118 DALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLD-LEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQS--LKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLN-----NRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTD-AVVVKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLL----DENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            +ALLK + +L   S +++  NW     PC  N++ W G+ C N +V  + L+ + L G L     L  + +L  LS  NN L GP+P+L     L  + LSYN F G IP +  E                         LP +  + L+ N   G IP F Q  L+  NVS N LEGP+PQ+  L+K   S++  N  LCG P + +C P                     + +     KK +                     F+ L      +RKQ ++       +E       +G +Q  +  +E+   P++  +    F +E    FDL DLLRASA++LG G  G +YK  + +   VVVKR K MN + ++EF + M+ LG + HENL+ ++++YY +EEKL++S F   G+L   LH N       LDW TRL IIK I++GLT+L+ +LPS  VPH +LKSSNVL+     + +   L D+  LP++   +    +   KSPE+AQ +++++K+DV+CFGII+LEV+TG+ P      + ++  DL +WV  ++    ++++ DVE+        E+LKL KI + C +   E+R  + +V+ +IEE+
Sbjct:   20 EALLKLRDSLS--SNSDLHGNWTGP--PCINNSSRWAGIACSNWHVVHIVLQGIQLAGSLPPCAFLHNITFLSKLSLRNNTLSGPVPNLTNLVYLEYVVLSYNRFWGSIPLEYIE-------------------------LPNLRVLELQSNYLDGHIPPFDQPTLRAFNVSYNHLEGPIPQTAVLQKFPKSSYDHNSNLCGSPLETSCPP--------PPPVVIAPSPSPLSPNIIPPKKKNNLQEWSFALIVAAAALVLFLVIFVSLCYSRKVHRKQAAK-------EEQQTGDGTSGWAQTKMPHLESLGDPEKKVELDF-FDKEMPAAFDLDDLLRASAQVLGKGKLGTTYKVTLESGPVVVVKRLKNMNELSKKEFTQQMQLLGNMRHENLVQILSFYYSKEEKLVISKFESSGTLFELLHENRGVGRVPLDWVTRLSIIKDIAKGLTFLHQSLPSHKVPHANLKSSNVLVIQRNSQTYHLKLTDFGFLPLVPSRKYNEDLAIGKSPEFAQGKKLSQKSDVYCFGIILLEVITGRIPGEISPGNDETMDDLSDWVRMVVNNDWSTDILDVEILAAKEDHDEMLKLTKIALDCTDLTPEKRPKMIQVLTRIEEI 592          

Query:  103 MDSTTDALLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCF--NGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLP-DLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPPFQGACNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSKKPSGXXXXXXXXXXXXXXXXXXXXFMFLNNRKQRSELDGTESLDESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDA-VVVKRYKQMNNVGREEFHEHMRRLGRL-THENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYALLPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFPENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEELYEGESDADYRSSVSSEGDDYT 1995
            ++S   ALLKF   +    K     NW+     C    A+WVG+ C     +V  + L  +GL G +    + +L  L+ LS  +N L G LP D+     L  LYL +N+FSG  P      + LL   +   N+FSG IP+++  L R+  + L+ N  SG IP+     LK LN+S N   G +P SLK    S+F GN +LCG P +  C+                    K    +    K   G                     +    R  +  L G  S D  S+     GS   +            A++ KL F       FDL DLLRASAE+LG G++G +YKA++  +  VVVKR +++  VG+ EF +HM  + R+  H N++P  AYYY ++EKLLV +++  GSL +HLHG+ ++    LDW +R++I  G+++G+ +++S        HG++KS+NVLL ++ E  + D  L P++N          Y++PE    R+I+ K+DV+ FG+++LE+LTGK    Y    +DS  DL  WV  +++E+ T+EVFD+E+ R  +   E++++L+I ++C  +  E R  ++EVV  IEE+   +SD   R S  SE D  T
Sbjct:   27 LNSDRQALLKFAAAVGHTQKL----NWNAAAPVC----ASWVGITCNLNKTSVTAIHLPAVGLFGSIPANSIGKLAALRVLSLHSNFLYGSLPSDILSIPSLEYLYLQHNNFSGVFPASLSPNLILLDFSF---NSFSGDIPTTVQNLTRLTALSLQNNSLSGAIPNLNLPKLKLLNMSYNNFNGSIPYSLKGYPDSSFTGNPQLCGAPLKN-CSKTSSSPSASPTYFPPSPTVQK-NHHATLIKKLGHGYITAVAIGGSAVLVVLVLMIVICCLKRTSKEGLKGKASGDGKSEMPKDFGSGVQE------------AEKNKLFFFDGCYFNFDLEDLLRASAEVLGKGSYGTTYKAVLDEETTVVVKRLREVI-VGKREFEQHMEVVERVGKHPNVVPPRAYYYSKDEKLLVYNYMPAGSLFAHLHGSRDAGRSPLDWDSRVKISLGVAKGIAHIHS--EGAKCSHGNIKSTNVLLTQDLEACITDVGLSPLMNFPATMSRATGYRAPEATDMRKISHKSDVYSFGVLLLEMLTGKTTLQY--PGHDSVIDLPRWVKSVVREEWTAEVFDLELLRQQHIEEEMVQMLQIALACVSKLPEARPSMDEVVRMIEEI--RQSDTKTRPSSESEFDVQT 630          

Query:  124 LLKFKKTLQLGSKTEVLSNWDPKKNPCNGNTANWVGVLCFNGNVRGLQLENLGLQGKLDLEPLAQLPYLKTLSFMNNMLDGPLPDLKKFKKLRSLYLSYNHFSGEIPDDEFEGMHLLRKLYLANNAFSGKIPSSLTTLPRVFDVGLEGNKFSGQIPDFMQKDLKRLNVSQNELEGPVPQSLKKMDPSNFAGNGKLCGPP---------------FQGA--------CNPHXXXXXXXXXXXXXXXXXXKCTGDSCGTSK-KPSGXXXXXXXXXXXXXXXXXXXXFMFLNN--RKQRSELDGTESLD-ESSKYTAAAGSSQMDVKSVETNPHPKRADQGKLSFVREDRQRFDLHDLLRASAEILGSGTFGASYKALIMTDAVV-VKRYKQMNNVGREEFHEHMRRLGRLTHENLLPLVAYYYRREEKLLVSDFVEXGSLASHLHGNHNSDMPVLDWPTRLRIIKGISRGLTYLYSTLPSLVVPHGHLKSSNVLLDENFEPLLNDYAL---LPVINMEQAQHLMMAYKSPEYAQHRRITKKTDVWCFGIIILEVLTGKFP----ENYLKQSYDSKADLVNWVNGMIKEKRTSEVFDVEMGRVGNSRGELLKLLKIGVSCCEEDVERRLDLNEVVEKIEEL 1932
            LL FK +    +K   L+ W+   + C      W GV C    V  L LENL L G    E L  L  L+ LS   N L GP+PDL     L+ L+LSYN FSG+ P      +  L +L L+ N  SG IPS++  L  +  + LE N+F+G I      +L+  NVS N L G +P+S      S FA N  LCG P               F GA         NP                     T  + GTSK  P                        FL N   K R     ++ L+ E   Y+++  S+Q  +            ++G++ F  E  +RF+L DLLRASAE+LG G FG +YKA++    VV VKR K     G+ EF +HM  LGRL+H N++ L AYY+ REEKLLV D++  G+L   LHGN       LDW TRL+I  G +RGL  ++++   L + HG++KS+N+LLD+     ++D+ L   +P      +      Y++PE    R++T+K+DV+ FG+++LE+LTGK P           Y    DL  WV  +++E+ T+EVFD+E+ R  +   E++ LL+I ++C     ++R  +++VV+ I+E+
Sbjct:   29 LLAFKSSSDASNK---LATWNSSSDLCT-----WFGVSCTRNRVSRLVLENLDLHGSF--ESLTDLTQLRVLSLKRNRLSGPIPDLSNLTALKLLFLSYNDFSGDFPAS-VTSLFRLYRLDLSYNNLSGHIPSTVNYLTHLLTLRLEVNRFAGSISGLNLPNLQDFNVSANRLTGEIPKSFSGFPESAFAQNPGLCGSPVLNCKGLVNNPTRPGFDGAIASPVMPAANPTVVASSPSSLPGNSTPNKSTNTRRN-GTSKISPEALIAIIVGDALVLVFVSLLLYCYFLRNFSAKMRQGKSSSKLLESEKIVYSSSPYSAQPGI------------ERGQMVFF-EGVKRFELEDLLRASAEMLGKGGFGTAYKAVLDDGNVVAVKRLKDAQIGGKREFEQHMAVLGRLSHPNIVSLRAYYFAREEKLLVYDYMSNGNLFWLLHGNRGPGRTPLDWTTRLKIAAGAARGLACIHNSCSPLKLTHGNIKSTNILLDKTGNARVSDFGLSVFVPPPPATSSAPRSCGYRAPETLDGRKLTQKSDVYAFGVLLLELLTGKCPSVVDSGGPGGGYGGLVDLPRWVQSVVREEWTAEVFDLELMRYKDIEEEMVGLLQIAMACTAASPDQRPRMSQVVKMIDEI 641