MDP0000292750, MDP0000292750 (mRNA) Malus spp. (apple)

Query:   61 GDVVIQMASPDAINITQLTSSMEESLKSVE-KTDWL---LRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            GD + + A     ++T +T +  + LKSVE KT  L   L  SAG  SCCIF+VPQ L E+N   Y PHIVSIGPYHHGK  L+M+++HKWR+L  +LART   G  + D+ + +A  EE IR CYSET + S+ E ++MMV+DG FIIE+F  V  + +     D DD IFN               ENQIPFFVLE LF  S  S       SS ++ +L+FF++A  QR  E L +Y  + G HLLDL R T I      P G     +  I+S KKLHQAGIKFK  E  SFLDI+F NGVLE+P +TVDD    + LN VAFEQCYNHC  HIT+Y  FM CL   P+D  FLCD  I+ENY G+DEEV  FF N+GKD  FDI  SYL ++F+DVNEH +N W+V+WAGFM TYFDTPWSF+SA A ++ L+LT IQ   A Y
Sbjct:    9 GDQIQENAGTSDDHVTSITEADRQWLKSVETKTKLLPKLLNNSAGKSSCCIFRVPQSLFEINKMAYQPHIVSIGPYHHGKVHLKMIEEHKWRFLGGVLARTQQHGIGINDFFKAIAPIEEKIRDCYSETIECSRQEFIEMMVLDGCFIIELFCIVGGIVQ----TDIDDPIFNMTRMFFFIMRDLLRLENQIPFFVLETLFETSILSSRK-QNVSSFAELALEFFDYAA-QRPPEVLRRYKDIRGKHLLDLFRSTIIPSSQEVP-GKISPFLQLIQSAKKLHQAGIKFKPRETDSFLDIEFSNGVLEIPLLTVDDFTTSVILNCVAFEQCYNHCSNHITSYVTFMGCLINAPSDAGFLCDYKIVENYFGTDEEVARFFNNVGKDVTFDIQRSYLSKVFEDVNEHYSNNWHVRWAGFMHTYFDTPWSFISALAAVVLLILTMIQAFFAFY 450          

Query:   61 GDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLL----RPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            GD   + A     ++T +T +  + LKSVEK   LL    + SAG  SCCIF+VPQ LVE+N + YHPHIVSIGPYHHGK  L+M+++HKWR+L  +LART   G  + D+ + +A  EE IR CYSET + S+ E ++MMV+DG FIIE+F  +  + +RD     DD IFN               ENQIPFFVLE LF  S  S       SSL++ +LKFF+ A  +R  E L +Y  + G HLLDL R T I                 I S KKLHQAGIKFK  E  SFLDI+F NGVLE+P +T+DD    + LN VAFEQCYNHC  HIT+Y  FM CL   P+D  FLCD  I+EN  G+DEEV  FF N+GKD  FD   SYL ++F+DVNEH +N W V+WA F  TYFDT WSF+SA A ++ L+LT IQ   A Y
Sbjct:    9 GDQSQENAETSNDHVTSITEADRQWLKSVEKKTKLLPKLLKKSAGKSSCCIFRVPQSLVEINKKAYHPHIVSIGPYHHGKVHLKMIEEHKWRFLGGVLARTQQHGIGINDFFKAIAPIEEKIRDCYSETIECSRQEFIEMMVLDGCFIIELFCIIGGIVQRDI----DDPIFNMTLMFFFIMRDLLKLENQIPFFVLETLFETSILSSRK-QIVSSLTELALKFFDHAA-ERPPEVLRRYKDIRGEHLLDLFRSTIIPASSQEVH-RKISPFQLIHSAKKLHQAGIKFKPRETDSFLDIEFSNGVLEIPLLTIDDFITSVILNCVAFEQCYNHCSNHITSYVTFMGCLINAPSDAGFLCDYKIVENSFGADEEVASFFNNIGKDVTFDTQWSYLSKVFEDVNEHYSNNWQVRWAEFKHTYFDTTWSFISALAAVVLLILTMIQAFFAFY 450          

Query:   43 NNGGRDGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFES-VDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGP 1410
            +  G+  D VI +++      ++  +S+E+ +  + K   LL  +AG  SCCIF+VP+ L ++N + Y PHIVSIGPYHHG    +M+++HKWR+L  +L RT     +L D+ + +A KEE+IR CYSE    S  +L++MM++DG FIIE+   V RL +       DD IFN               ENQIPFFVLE LF     +    D   SL++ +L+FF++AV +R  E L+++    G HLLDL R T+I      P  +A+   +  I+S KKL  +GIKFK     SFLDI F +GVL +P +TVDD      LN VAFEQCY HC KHIT+Y  FM CL  TPAD  +L D  IIENY G+D+EV  FF ++GKD  FDI  SYL +LFKDVN++  N ++++WAGF  TYFD+PWSFMSA A LI L+LT IQ   A+Y    P
Sbjct:   13 HENGKTSDHVIAIST----EASEWLASLEDKISKMPK---LLNKTAGKSSCCIFRVPKSLAQINEKAYQPHIVSIGPYHHGNDQFQMIEEHKWRFLGAVLTRTKAKDISLDDFFKAIAPKEEEIRECYSENIGYSSHQLIEMMILDGCFIIELLCIVARLVQ----THLDDPIFNMAWMFSFLMRDLLRLENQIPFFVLESLFGLVSVTLD--DSSRSLTELALEFFDYAV-ERPAEFLDRFKDKKGKHLLDLFRSTFIPPPQGKPNEDAYSPFLQLIQSAKKLRLSGIKFKPKRTDSFLDISFSHGVLRIPPLTVDDFTSSFLLNCVAFEQCYKHCSKHITSYVTFMGCLINTPADAGYLSDHRIIENYFGTDDEVAKFFNDVGKDITFDIQRSYLSKLFKDVNKYYRNNFHIKWAGFKHTYFDSPWSFMSAMAALILLVLTIIQAFFAVYPYASP 455          

Query:   58 DGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHD------IPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            + DVV+++   +   + ++   + E  +       LLR SAG  SCCIF+VP+ LVE+N ++Y PHI+SIGPYH G+P L+M+++HKW YL  L+ART   G  L DYL+ +   E + R CYSE   L   + ++M+V+DG FII+ F ++ ++       +PDD + +               ENQ+PFFVL+ LF+ +K   P  +   SL+   L FFN   LQR DE L+K+ +L G H LDL+R ++I +      + H P          I+ V KL +AGIK K G+A SFL +KFRNGV+E+P +T+DD     F N VAFE C+  C KHITTYA  ++CL  T  D   LC+RNI ENY G+D  V  F  NLGKD  FD +  YL +LF DVNE+ +N W+VQ AG   TYFDTPWSF+SA A  I LLLT +QT   +Y
Sbjct:    6 NNDVVVRIWEVNKERLARMQQKISEEPR-------LLRKSAGRSSCCIFRVPRTLVEINSRSYQPHIISIGPYHRGEPHLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMEARECYSEIIHLDTHDFLEMLVLDGCFIIDFFRKIGKMHP----FEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTK--MPGEESGPSLASLVLGFFN-NTLQRPDEILQKHCNLKGKHFLDLLRLSFIPEEQELGTLDHRP-------THLIQCVSKLRKAGIKLKSGKADSFLTVKFRNGVMEMPPVTIDDFLTCFFQNCVAFELCHKDCTKHITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVY 436          

Query:   58 DGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHD------IPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            + DVV+++   +   + ++   + E  +       LLR SAG  SCCIF+VP+ LVE+N ++Y PHI+SIGPYH G+P L+M+++HKW YL  L+ART   G  L DYL+ +   E + R CYSE   L   + ++M+V+DG FII+ F ++ ++       +PDD + +               ENQ+PFFVL+ LF+ +K   P  +   SL+   L FFN   LQR DE L+K+ +L G H LDL+R ++I +      + H P          I+ V KL +AGIK K G+A SFL +KFRNGV+E+P +T+DD     F N VAFE C+  C KHITTYA  ++CL  T  D   LC+RNI ENY G+D  V  F  NLGKD  FD +  YL +LF DVNE+ +N W+VQ AG   TYFDTPWSF+SA A  I LLLT +QT   +Y
Sbjct:    5 NNDVVVRIWEVNKERLARMQQKISEEPR-------LLRKSAGRSSCCIFRVPRTLVEINSRSYQPHIISIGPYHRGEPHLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMEARECYSEIIHLDTHDFLEMLVLDGCFIIDFFRKIGKMHP----FEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTK--MPGEESGPSLASLVLGFFN-NTLQRPDEILQKHCNLKGKHFLDLLRLSFIPEEQELGTLDHRP-------THLIQCVSKLRKAGIKLKSGKADSFLTVKFRNGVMEMPPVTIDDFLTCFFQNCVAFELCHKDCTKHITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVY 435          

Query:   58 DGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHD------IPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            + DVV+++   +   + ++   + E  +       LLR SAG  SCCIF+VP+ LVE+N ++Y PHI+SIGPYH G+P L+M+++HKW YL  L+ART   G  L DYL+ +   E   R CYSE   L   + ++M+V+DG FII+ F ++ ++       +PDD + +               ENQ+PFFVL+ LF+ +K   P  +   SL+   L FFN   LQR DE L+K+ +L G H LDL+R ++I +        H P          I+ V KL +AGIK K G+A SFL +KFRNGV+E+P +T+DD     F N VAFE C+  C KHITTYA  ++CL  T  D   LC RNI ENY G+D  V     NLGKD  FD +  YL +LF DVNE+  N W+VQ AG   TYFDTPWSF+SA A  I LLLT +QT   +Y
Sbjct:    5 NNDVVVRIWEVNKERLARMQQKISEEPR-------LLRKSAGRSSCCIFRVPRTLVEINSRSYQPHIISIGPYHRGEPXLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMXARECYSEIIHLXTHDFLEMLVLDGCFIIDFFRKIGKMHP----FEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTK--MPGEESGPSLASLVLGFFN-NTLQRPDEILQKHCNLKGKHXLDLLRLSFIPEEQELGTXDHXP-------THLIQCVSKLRKAGIKLKSGKADSFLTVKFRNGVMEMPPVTIDDFLXCFFQNCVAFELCHKDCTKHITTYATLLDCLINTSKDVGXLCXRNIFENYFGTDAXVARXINNLGKDVTFDPDNCYLSKLFNDVNEYYXNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVY 435          

Query:   91 DAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI--HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKG-EAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQT 1380
            D  NI          LK  E   +L + +AG RSCCIF+VPQ LVEVNG+ Y P IVSIGPYH  +P L M+++HKWRYL  LL+RT   G  L D  + +A  E + R CYSET  L   + +QMM++DG FIIE+F +V RL       + +D +                 ENQIPFF+L  L+  +K   P      +LS  +L FFN + LQ+ DE L+    + G HLLDL+R ++I  +D    PR         I  V KL +AGIK     E+ SFL++KFR GV+E+P +TVDD      LN VA EQCY+ C KH T Y   ++CL  T  D  +LCDRN++EN+LG++ EV  F  N GKD A D++  YL  LF DV+++  N W+VQWA F  TYFDTPWSF+S  A  I LLLT  QT
Sbjct:   11 DISNIIDRERLASMELKISENPKFLCK-AAGKRSCCIFRVPQSLVEVNGKAYQPRIVSIGPYHRNQPRLNMIEEHKWRYLGSLLSRTNTIGFVLEDLFKAIAPLESEARECYSETINLDSHDFIQMMILDGCFIIELFRKVARLVP----FEREDPLLTMVWILPFFYRDFLKLENQIPFFILNQLYQVTK--LPGEKSTPTLSTLALLFFNNS-LQKPDESLQN--DVQGKHLLDLVRSSFIPKNDEETEPRKRVMTPTHVILCVSKLRRAGIKINPSKESESFLNVKFRRGVIEMPSLTVDDFMSSFLLNCVALEQCYSGCSKHFTAYITLLDCLVNTYRDVEYLCDRNVVENHLGTEGEVASFINNAGKDVAVDLDLCYLSLLFNDVHKYYINSWHVQWASFKHTYFDTPWSFISLLAASILLLLTVAQT 433          

Query:  163 LLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAA-SFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            LL  +A   SCCIFKVPQ  +++NG++Y PH+VSIGPYHHG+  L+M+++HKWRYL  +L+RT   G  L   L+ +   E+  R CYS+       E ++MMVVDG FIIE+F +V  + E     + DD I                 ENQIPFFVLE LF+ ++   P  +   SL K SL FFN+A LQR D  + ++  L   HLLDL+R ++I D       +   S   I SV KL +AGI+  +G    SFL +KF+NGV+E+P +T+D+      LN VAFEQC+N   KH TTYA  ++CL  T  D   L D NIIENY G+D EV  F  +LGK+ AFDI   YL  LF DV+++  N  +VQWA F  TYF TPWSF+SA A LI LLLT  QTV  IY +
Sbjct:   11 LLTKAAANSSCCIFKVPQRFIDINGKSYQPHVVSIGPYHHGEEHLKMIEEHKWRYLGSILSRTQNKGLDLEVLLKAIQPLEKKARECYSQIIHFDTDEFIEMMVVDGCFIIELFRKVGNVVE----FEVDDPIVTMAWIIPFFYRDLLRLENQIPFFVLECLFDITR--MPGEESGPSLCKLSLDFFNYA-LQRPDNIIARHNDLNAKHLLDLVRSSFI-DFEQGQSLHVDTSTPMIHSVSKLRRAGIELSQGNPEDSFLVVKFKNGVIEMPTITIDETVTSFLLNCVAFEQCHNGSSKHFTTYATLLDCLVNTFKDVEHLSDCNIIENYFGTDSEVASFINDLGKEVAFDIERCYLSSLFHDVDQYYKNSRHVQWASFKYTYFSTPWSFVSALAALIILLLTVSQTVYTIYGT 416          

Query:  163 LLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAA-SFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            LL  +A   SCCIFKVPQ  +++NG++Y PHIVSIGPYHHG+  L M+++HKW YL  +L+RT   G  L   L+ +   E   R CYS+   L   E V+MMV+DG+FIIE+F +V  +       + DD I                 ENQIPFFVLE LF  ++   P  +   SLSK +L FFN A LQR D  + ++ +    HLLDL+R ++I      PR     S   I+SV KL +AGIK  +G+ A SFL +KF+NGV+E+P +T+DD      LN VAFEQC++    H TTYA  ++CL  T  D  +LCD NIIENY G+D EV  F  +LGK+ AFDI   YL ++F DV+++  + W++QWA F  TYF TPWSF+SA A LI LLLT  QT   IY +
Sbjct:   11 LLTKAAANSSCCIFKVPQRFIDINGKSYQPHIVSIGPYHHGEAHLRMIEEHKWGYLGSMLSRTQNNGLDLEVLLRAIQPLEMKARECYSQIIHLDTCEFVEMMVLDGVFIIELFRKVGEIVG----FEADDPIVTMAWIIPFFYRDLLRLENQIPFFVLECLFEITRT--PGEESGPSLSKLALDFFNNA-LQRPDYIIARHNNGKAKHLLDLVRSSFIDSEQAQPRC-VDTSTPMIQSVSKLRRAGIKLGQGDPADSFLVVKFKNGVIEMPTITIDDTISSFLLNCVAFEQCHSGSSNHFTTYATLLDCLINTIKDVEYLCDCNIIENYFGTDSEVARFVNDLGKEVAFDIERCYLSEMFSDVHQYYKDRWHLQWASFKFTYFSTPWSFISAMAALIILLLTVAQTFYTIYGT 416          

Query:  124 MEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI-----HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKK-GEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            M E LK   +   LL  +AG  +C IF+VPQ +++ NG+ Y P +VS+GP+H G+  LEM+Q+HKWRYL  LL RT     TL DY++ V   EE+ R CYSET  +   E  +MMV+DG F++E+F +V  L       +P+D +                 ENQIPFFVLE LF+ ++    N +  +SL   +  FFN  ++ R+DEDL ++  L   HLLDL+R ++I     H  P    G        I S+ KL +AGIK ++  +A SFL ++FR+G +E+P +TVDD       N VA+EQC+  C  H TTYA  ++CL  T  D  +LCD+NIIENY G+D E+  F  +LG+D AFDI   YL  LF++VNE+  + W+V+WA F  TYF++PWSF+SA A L+ L+L+ IQTV  ++
Sbjct:   28 MHEKLKEPPR---LLSSAAGKPTCSIFRVPQSMIDCNGRWYEPRVVSVGPFHRGQIRLEMIQEHKWRYLNVLLTRTQNL--TLEDYMKSVKSVEEEARECYSETIHMDSEEFNEMMVLDGCFLLELFRKVNNLVP----FEPNDPLVAMAWVLPFFYRDFLCLENQIPFFVLETLFDLTRGDNKN-ETNASLPSLAFAFFN-NMMHRTDEDLARFKELRAKHLLDLLRSSFIPESQLHTPPETNPGKEKTPSHIIHSISKLRRAGIKLRELKDAESFLVVRFRHGAIEMPAITVDDFMSSFLENCVAYEQCHVACSMHFTTYATLLDCLTNTYKDVEYLCDQNIIENYFGTDTELARFVNSLGRDVAFDITQCYLKDLFEEVNEYYKSSWHVEWATFKFTYFNSPWSFVSALAALVLLVLSVIQTVYTVF 446          

Query:   58 DGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHD------IPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            + DVV+++   +   + ++   + E  +       LLR SAG  SCCIF+VP+ LVE+N ++Y PHI+SIGPYH G+P L+M+++HKW YL  L+ART   G  L DYL+ +   E + R CYSE   L   + ++M+V+DG FII+ F ++ ++       +PDD + +               ENQ+PFFVL+ LF+ +K   P  +   SL+   L FFN   LQR DE L+K+ +L G H LDL+R ++I +      + H P          I+ V KL +AGIK K G+A SFL +KFRNGV+E+P +T+DD     F N VAFE C+  C KHITTYA  ++CL  T  D   LC+RNI ENY G+D  V  F  NLGKD  FD +  YL +LF DVNE+ +N W+VQ AG   TYFDTPWSF+SA A  I LLLT +QT   +Y
Sbjct:    5 NNDVVVRIWEVNKERLARMQQKISEEPR-------LLRKSAGRSSCCIFRVPRTLVEINSRSYQPHIISIGPYHRGEPHLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMEARECYSEIIHLDTHDFLEMLVLDGCFIIDFFRKIGKMHP----FEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTK--MPGEESGPSLASLVLGFFN-NTLQRPDEILQKHCNLKGKHFLDLLRLSFIPEEQELGTLDHRP-------THLIQCVSKLRKAGIKLKSGKADSFLTVKFRNGVMEMPPVTIDDFLTCFFQNCVAFELCHKDCTKHITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVY 435          

Query:  190 SCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKG-EAASFLDIKFR--NGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLA 1389
            +CCI++VPQ L +VN + Y P +VSIGP HHG+  L  M++HK RYL++ L R   T  TL + +++++ +E+  R CY E   +S  E V+M++VDG FIIE+    +  + R     PDD IFN               ENQ+P F+L  L++Q +  R + + Y S    S+ FF F       + ++        H +DL+          P   + F+ +  I S  +LH+AG++F+ G +    LDI +R  +GVL++P++ +DD    LF N +AFEQC+     +IT Y   M+ L  T  D   L ++ IIEN LG +  VT+ F NL  +A    +  YL  + + ++E+C+  WN   A     YF +PW   S  A +I LLLT IQT+ +
Sbjct:   26 TCCIYRVPQKLRKVNMEAYTPRVVSIGPLHHGEEHLIAMEEHKLRYLQNFLHR---TRKTLEECVEIISREEKTARDCYMEPINMSSKEFVEMILVDGCFIIEVILGFQNWNGRTG--KPDDRIFNKPWLIYDVRRDMTLLENQLPLFLLLTLYSQLEVPR-HQNHYDSFLLLSVNFFKFYSQMPEAKKIK--------HFVDLLIVCQQPSSTRPQNRSDFKFM--IPSATQLHEAGVRFELGSKEERLLDIVYRRSDGVLKIPRLKLDDKCEPLFRNLIAFEQCHYRERLYITDYITLMDQLINTTKDVDVLVNKGIIENLLGDNVAVTNLFNNLLINATTGTD-FYLADVTEGLSEYCDVPWNRWKAALRHDYFCSPWRGASTIAAVILLLLTLIQTIFS 411          

Query:  199 IFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLL-ARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGV--HLLDLIRKTYIHDIPHPPRGNA-----------FESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCN----NVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGP 1410
            I++VP+ L EV+   + P I+SIGP+H+G P L  M++HK RYL  LL +RTP  G    + +      E+  R CY+    +  ++ VQMMV+DG F++E+  R+    ER+  VD  D IF                ENQ+PFFVL+ LF     +     E   L    L FF+  +L R  +++E   +  G   H+L++ R T++  +                    +    I SV +L +AG+K KK E    LDI F+ GVL++P + +DD    LFLNFVA+EQC        T Y +F + L  + AD   L    II + LGSD++V   F  LG++  +D++  YL Q  K VN +C     + W V +      YF  PW+F S  A +  LLLT  QT   +Y    P
Sbjct:   42 IYRVPRNLREVHKNAFVPKIISIGPFHYGDPGLRFMEEHKVRYLLRLLGSRTPEKGGQAEELMSQEL--EQKTRQCYTGAFDIDSNDFVQMMVIDGCFVLELL-RLYNRFEREKNVD--DPIFTIRWMLRTLQRDLLKLENQLPFFVLKKLFELISLA-----EDPPLIDLVLTFFD-PLLPR--KNIEGNLNPEGEFDHMLEVFRSTFLSSVNQDITSGCEQLKISVNVPLVQERQLIHSVTELEKAGVKLKKREDCDLLDINFQAGVLKIPPLYIDDNTAVLFLNFVAYEQC-EDTKPFFTNYLMFFDSLINSSADVGILHKNGIINHVLGSDQDVADLFNKLGREVVYDLDECYLSQQIKRVNNYCKTYYASKWRVWFTNLKHDYFSNPWTFFSLLAAIALLLLTTAQTYYTVYGYYSP 449          

Query:  187 RSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTP-PTGPTLADYLQLV-----AFKEEDI-----------RGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSK--PSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDK------------IRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCN----NVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYA 1398
            +S  +++VP+ +  +    + P I+SIGP+H+  P L +M++HK RYL  LL   P   G  + D  Q V     A + ED+           R  YSE  ++   EL+QMMV+DG F++E+     +    +   DP   IF                ENQ+PFFVLE L+   +     P  D   +     L   N       +E+ +        H+LD+ R T++  I    +   ++ + K            I  V +L +AG++FK  E    LDI F++G+L++P + +DD  V LFLN VA+EQC        T + +F + L  +  D   L    II + LGSD++V + F  LG++  +D++  YL Q   DVN++C     + W+V +   +  YF +PW+F+S  A +  LLLT  QT  A+YA
Sbjct:   49 KSWTVYRVPKSMRGIQKNAFLPKIISIGPFHNKDPGLRIMEEHKMRYLLRLLESGPRENGERVEDSAQQVPQVVKAIRLEDLAESMRMLEQKTRENYSEDLQIDSDELIQMMVIDGCFVLELLRLYFKFDNEEEVEDP---IFTTRWMLRTLQRDLLKLENQLPFFVLEKLYELIRLVDDPPLVDLVVTFFDPLLPRKNIKGKLNPNEEFD--------HMLDVFRSTFLSSINERTKPAGWKQLQKLDNIPLVEERQLIHCVTELQEAGVRFKMREDLDLLDISFKDGMLKIPPLYIDDNTVPLFLNLVAYEQCDQDAKPFFTNFCMFFDSLINSHTDVGILHKNGIINHVLGSDKDVANLFNKLGREIVYDLDECYLSQQMMDVNDYCKQYFASKWHVWFTNLIRDYFSSPWTFLSLLAAIALLLLTTAQTFYAVYA 476          

Query:  121 SMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIF------FRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHP-PR------GNAFESVDK-----IRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGPG 1413
            S++E L+   + D     +      CI+++P +L E + + Y P IVS+GPYHHG+  L  M +HKWR L  +L RT      +  YL  +   EE  R CY  T  LS +E V+MMV+DG FI+E+F      F+    +  DP       +F                ENQIP F L      +K  R   +  SSL   +                +     GG+H L++ R++ +   P P PR       ++    DK     I  V +L +AGIKFKK +   F DIKF+NG+L +P++ + D    LFLN +AFEQC+  C   IT+Y +FM+ L  +P D  +L    I+E++LGS+ EV   F  L ++  FDIN SYL                             PW+ +S  A ++ L LT  QT  A+Y+   PG
Sbjct:   80 SIKEKLEQAHQDD----AADSWAKLCIYRLPHYLREGDDKAYIPQIVSLGPYHHGRRRLRNMDRHKWRSLHHILKRT---NHDIEIYLDAMKELEEKARACYEGTICLSSNEFVEMMVLDGCFILELFRGVAGGFKHLGYARNDP-------VFAIRGSMHSIQRDMIMLENQIPLFPL------TKSDRNRLE--SSLGYTTT--------------FDPLGDQGGLHCLEVFRRSLLRTGPRPVPRIWMKRWSHSNRVADKRRQQLIHCVTQLREAGIKFKKRKTDRFWDIKFKNGILRIPRLLIHDGTKSLFLNLIAFEQCHLDCSNDITSYVIFMDSLINSPEDVGYLHYCGIMEHWLGSESEVADLFNRLCQEVVFDINDSYLSSF--------------------------PWTIISFVAAVVLLALTFAQTFYAVYSYYRPG 466          

Query:  190 SCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRP---NCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKG----EAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTV 1383
            +CCI++VPQ L + N + Y P +VSIGP HHG+  L  M++HK RYL+  L+ T  T   L + ++++  +EE  RG Y E+ K+S+ E V+M++VD  FIIE+             ++  D I+N               ENQ+PFF+L  L++   P  P   N ++Y+         ++F +L +      +  H   V LL +  +     +P  P   +F+ V  I +   L +AG++FK G    +    LD+ + NGVL++P + + +    LF N +A+E+C++H   +IT Y   M+ L  T  D + L  + II N+LG +  V + F  L  D        +   +++ +N++ ++ WN   A     YF +PW   S  A +I L+LT IQTV
Sbjct:   26 TCCIYRVPQKLRKANMEAYTPRVVSIGPLHHGEEHLVAMEEHKLRYLQKFLSETRKT---LEECVEIIYREEEKARGYYMESIKMSREEFVKMILVDACFIIEVILGFSSSHS----IETGDRIYNKPRLFIDVRRDMTLLENQLPFFLLLSLYSLRAPPGPLPENQNDYAH--------YSFLLLSKKISSRHEIKHF--VDLLIVCLQPSSSSLP--PESKSFKFV--IPTATYLREAGVRFKLGSKDKDNDKLLDLDYNNGVLKIPHLILQEKCESLFRNLIAYEECHDHAQTYITDYMYLMDHLINTTKDVNLLVRKGIISNHLGDNHAVKNLFNRLLIDTTTCKETFHFAGIYEKLNKYYDSPWNRWQATLRHDYFSSPWRGASTIAAVILLVLTLIQTV 409          

Query:  199 IFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXX---ENQIPFFVLEMLF--NQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIP--HPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGPGGHGGRQESN 1440
            I++VP  + ++N + Y P  VS GPYHHG+  L+ M+ HK R L     R+      L + L  V    +D         +   S  +Q+M+VDG F++EI        +     DP+D IF+                  ENQ+P  VL+ L      K   P       ++K  LKFF  +     +  + K      +H+LD+ RK+ + + P   PP                    GI+ KK                       +D    +FLN +AFE+ +      +T++  FM+ +     D   L  R II++ LGSD+ V   F +L KD   D +   L  + K VN++C   WN   A  + TYF  PW+ +S  A      LT  QTV  IY    P G      S+
Sbjct:   29 IYRVPTCVTDLNKKAYKPQAVSFGPYHHGEEHLQTMEDHKRRALLHFFKRSDKPIKLLVESLAEVVQDLKDSYDLLDPAWQKDTSAFLQLMIVDGCFMLEILRTATHTMDD---YDPNDPIFSDHGRLYIMPYVRRDMLMLENQLPMLVLDKLLAVESDKAKDPEL-----INKLILKFFTTS---SPEAGMGKC-----LHVLDVYRKSLLQEGPGRKPP--------------------GIRMKK-----------------------NDTTESMFLNLIAFERLHVGAGNEVTSFIFFMDNIIDNAKDVILLHSRGIIQSALGSDKAVAKLFNSLSKDITLDPDGP-LYGVHKKVNDYCRKSWNEWRANLIHTYFRNPWAILSLIAAAFLFALTIAQTVFTIYPYYHPSGDSSSSPSD 389          

Query: 2362 FIPEQNGIAXRKNRTIVEXAXTMLYEK-------------------KCPTKALENKTXFEEFCGRKPGVKHLRIFGSVCYTHVPTQLRQKLDETGQKGVFVGYGTREKGYRVYDLKHNKIIVSRSVIFNEDAAXNWE 2715
            + P+QNG+  RKN+T++E A  MLYEK                   +CPTKAL NKT  E + GR P V+H ++FG +CY+ VP + R KLDET +K +F+GY ++ KGYR+Y+LK NK+I+SR VIF E AA NWE
Sbjct:  514 YTPQQNGVVERKNQTVMEMAKAMLYEKGLPKFFWVEAVNTVVYLLNRCPTKALLNKTLIEAWSGRNPSVRHFKVFGCLCYSQVPKERRSKLDETSEKCIFMGYSSQSKGYRLYNLKTNKLIISRYVIFYEKAAWNWE 650          

Query: 1546 VGMLDAHMEDQLMKDAKALGIIQSAISNEIFPRIVNQKTSKGAWDLLQEEFHGDKQARSVKLQSLRREFEYMRMKENESLSVYLTRLFELINQMNLM----------------------VRTSLIKENCKRTSDLNIVTVQEVVGSLKSYELRLSRHVDEITSTEHAF----------SIMGLVPKAQNRPFTLGNHSKG-------------------------------------------KKNWKSMFRKWENNTRQPERQDNAMMFYTCHKASVQENS----GVWYLDSGCSNHMTNXESLLINIDRSIRCKVKMGTGDLVDSVGKGTLIVETKRGTLIV 2340
            V  + A+ E++L KD KA+  + S +++ IF +I+N +T K  WD LQ EF G ++ ++V+L  L+REFE M+MK++E +  Y  RL +++NQ+ L+                       + S I+E+C    DL  +T+ E+   L + E R+    DE  +TE AF          ++ G      N+    G+  KG                                           KK       K   N  + ++ D+  +F      S  E S      W +DSGC++HMT   S+  +IDRS++ KVK+G G++V + GKGT+ + TKR T IV
Sbjct:   54 VAQMKAYEEEKLKKD-KAITCLHSGLTDHIFTKIMNLETPKLVWDKLQGEFEGSERFKTVRLLKLKREFELMKMKDDEFVKDYSGRLMDVVNQIRLLGEAFTDQKVVEKIMVLVPQKFEAKISAIEESC----DLQTLTIVELTSKLHAQEQRVLMRGDE--ATEGAFQANHEGKNSGNLQGKKFFKNNKEKAEGSSRKGKFPSCSHCRRTNHAEKDCWHKGKPLFNCNFCNKLGHSEKYCRAKKKQSQQQPKQNANVTEEDKNDDEHLFMASQALSSHELSSHELNTWLIDSGCTSHMTKYLSIFTSIDRSVQPKVKLGNGEVVQAKGKGTIAISTKRRTKIV 390          

Query:   97 INITQLTSSM-EESLKSVEKT---DWL--LRPSAGM-----RSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRP 675
            IN+ +L   M +ES  +  +T   DW+  ++   G+      +  I+KVP  L  VN + Y P IVSIGP+H GK DL  M++HKWRY+  L+ RTP    +L +  + +   EE  RGCY+E  K +K EL +M++VDG FI+E+F    R S RD  VD  D IFN               ENQIPFFVL+ L+    P  P
Sbjct:   15 INLVELKGKMRQESPPTPSETPTSDWMHPIKVKLGILRERSMNLSIYKVPNKLRHVNEEAYSPRIVSIGPFHQGKRDLLAMEEHKWRYMLSLVHRTPNPEKSLDECGKSIIELEEKARGCYAENIKFNKKELAEMLLVDGCFILELFL---RRSLRD-FVDKSDPIFNNAWMVPTLQHDLALLENQIPFFVLQNLYEFILPFAP 214          

Query:  118 SSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIP--------------HPPRGNAFESVDK-----IRSVKKLHQAGIKFK--KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLC-DRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI--YASDGPG 1413
            S+    L S  K   LL  SAG  SCCIF+VP+  V +N + Y P +VSIGPYH+G+  L+M+QQHK R L+  L             ++ V   E+ IR  YSE  K    +L+ MMV+DG FI+ +F  +    E       +D IF+               ENQ+PFFVL+ L+  SK         S L++ +  FF   +  +     EK+ +    HLLDLIR+T++ +                H  +     SVD      I S K+L   GIKF+  + +  S L+++ +   L++PQ+  D      FLN VAFEQ Y      ITTY VFM CL     D +FL  D+ IIEN+ GS+ EV+ FFK + KD  F+++ SYL  +FK VNE+    +N  WAGF  T+F++PW+F+S+ AVL  +LLT +Q+ +AI  Y +D  G
Sbjct:   21 SAFRNYLSSGSKEPVLLLESAGKESCCIFRVPESFVALNPKAYKPKVVSIGPYHYGEKHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGH-DLMFMMVLDGCFILMVFLIMSGNIELS-----EDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSK-----IGVSSDLNRIAFHFFKNPI-DKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQFYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDKKG 464          

Query: 2368 PEQNGIAXRKNRTIVEXAXTMLYEKKCPTKA----------LENKTX-----FE----EFCGRKPGVKHLRIFGSVCYTHVPTQLRQKLDETGQKGVFVGYGTREKGYRVYDLKHNKIIVSRSVIFNE 2694
            P+ NG+A R NRTIVE   +ML   K P             L N++      FE     +  ++    HL++FG   + HVP + R KLD+     +F+GYG  E GYR++D    K+I SR V+F E
Sbjct:  579 PQHNGVAERMNRTIVEKVRSMLRMAKLPKSFWGEAVQTACYLINRSPSVPLAFEIPERVWTNKEVSYSHLKVFGCRAFAHVPKEQRTKLDDKSIPCIFIGYGDEEFGYRLWDPVKKKVIRSRDVVFRE 706          

Query: 2368 PEQNGIAXRKNRTIVEXAXTMLYEKKC-------------------PTKAL--ENKTXFEEFCGRKPGVKHLRIFGSVCYTHVPTQLRQKLDETGQKGVFVGYGTREKGYRVYDLKHNKIIVSRSVIFNEDAAXNWENMETMHFSVPF 2748
            P+ NG++ R  RTI E A TM+   K                    P++AL   +KT +E +  +KP +KHLR+FG+  Y H+  + + K D+   K +FVGY     G++++D  + K IV+R V+ +E    N  N   + F   F
Sbjct:  579 PQLNGVSERMIRTITEKARTMVSGAKLDKSFWGEAVLTATYLINRIPSRALVDSSKTPYEMWHNKKPYLKHLRVFGATVYVHIKNK-QGKFDDKSFKSIFVGY--EPNGFKLWDAVNEKFIVARDVVVDE---TNMVNSRAVKFETVF 720          

Query:  199 IFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEI-----FFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDE-YSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI-----HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFR 954
            IF VP+ L+  +  +Y PH VSIGPYH  KP+L  M+++K    R +  R         D ++ +   E  IR CY +    +   L+ +M VD  F+IE      F +VE L  R   V  ++ +                 ENQIP FVL         S  + D+   S+     K  +  V++  D+ + K       H+LD + +  +      ++      N  +     R+++ + +   +FK+  A+   D+  R
Sbjct:   45 IFNVPKALMCSHPDSYTPHRVSIGPYHCLKPELHEMERYKLMIARKI--RNQYNSFRFHDLVEKLQSMEIKIRACYHKYIGFNGETLLWIMAVDSSFLIEFLKIYSFRKVETLINR---VGHNEIL-----------RDIMMIENQIPLFVLRKTLEFQLESTESADDLLLSVLTGLCKDLSPLVIKFDDDQILKAQFQECNHILDFLYQMIVPRIEEEELEEDDEENRADENGGNRAIRFMDEIKHQFKRVFASRPADLILR 291          

Query:  817 IHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKF--RNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            I DI  PP          I SV  LH+AG++FK     +   + F   +G   +P + +D     +  N VA+E          T Y   +N +  +  D   L ++ ++ + L SD+E    +  + K         +L +  +DVN +    W V+    +  Y    W  ++  A ++ L+L ++Q    +++S
Sbjct:  331 ILDIEKPPLVEELT----IPSVSDLHKAGVRFKPTAHGNISTVTFDSNSGQFYLPVINLDINTETVLRNLVAYEATNTSGPLVFTRYTELINGIIDSEEDVRLLREQGVLVSRLKSDQEAAEMWNGMSKSVRLT-KVGFLDKTIEDVNRYYTGRWKVKIGRLVEVYVYGSWQILAFLAAVLLLMLVSLQLFSLVFSS 522          

Query:   61 GDVVIQMASPDAINITQLTSSMEESLKSVE-KTDWL---LRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            GD + + A     ++T +T +  + LKSVE KT  L   L  SAG  SCCIF+VPQ L E+N   Y PHIVSIGPYHHGK  L+M+++HKWR+L  +LART   G  + D+ + +A  EE IR CYSET + S+ E ++MMV+DG FIIE+F  V  + +     D DD IFN               ENQIPFFVLE LF  S  S       SS ++ +L+FF++A  QR  E L +Y  + G HLLDL R T I      P G     +  I+S KKLHQAGIKFK  E  SFLDI+F NGVLE+P +TVDD    + LN VAFEQCYNHC  HIT+Y  FM CL   P+D  FLCD  I+ENY G+DEEV  FF N+GKD  FDI  SYL ++F+DVNEH +N W+V+WAGFM TYFDTPWSF+SA A ++ L+LT IQ   A Y
Sbjct:    9 GDQIQENAGTSDDHVTSITEADRQWLKSVETKTKLLPKLLNNSAGKSSCCIFRVPQSLFEINKMAYQPHIVSIGPYHHGKVHLKMIEEHKWRFLGGVLARTQQHGIGINDFFKAIAPIEEKIRDCYSETIECSRQEFIEMMVLDGCFIIELFCIVGGIVQ----TDIDDPIFNMTRMFFFIMRDLLRLENQIPFFVLETLFETSILSSRK-QNVSSFAELALEFFDYAA-QRPPEVLRRYKDIRGKHLLDLFRSTIIPSSQEVP-GKISPFLQLIQSAKKLHQAGIKFKPRETDSFLDIEFSNGVLEIPLLTVDDFTTSVILNCVAFEQCYNHCSNHITSYVTFMGCLINAPSDAGFLCDYKIVENYFGTDEEVARFFNNVGKDVTFDIQRSYLSKVFEDVNEHYSNNWHVRWAGFMHTYFDTPWSFISALAAVVLLILTMIQAFFAFY 450          

Query:   61 GDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLL----RPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            GD   + A     ++T +T +  + LKSVEK   LL    + SAG  SCCIF+VPQ LVE+N + YHPHIVSIGPYHHGK  L+M+++HKWR+L  +LART   G  + D+ + +A  EE IR CYSET + S+ E ++MMV+DG FIIE+F  +  + +RD     DD IFN               ENQIPFFVLE LF  S  S       SSL++ +LKFF+ A  +R  E L +Y  + G HLLDL R T I                 I S KKLHQAGIKFK  E  SFLDI+F NGVLE+P +T+DD    + LN VAFEQCYNHC  HIT+Y  FM CL   P+D  FLCD  I+EN  G+DEEV  FF N+GKD  FD   SYL ++F+DVNEH +N W V+WA F  TYFDT WSF+SA A ++ L+LT IQ   A Y
Sbjct:    9 GDQSQENAETSNDHVTSITEADRQWLKSVEKKTKLLPKLLKKSAGKSSCCIFRVPQSLVEINKKAYHPHIVSIGPYHHGKVHLKMIEEHKWRFLGGVLARTQQHGIGINDFFKAIAPIEEKIRDCYSETIECSRQEFIEMMVLDGCFIIELFCIIGGIVQRDI----DDPIFNMTLMFFFIMRDLLKLENQIPFFVLETLFETSILSSRK-QIVSSLTELALKFFDHAA-ERPPEVLRRYKDIRGEHLLDLFRSTIIPASSQEVH-RKISPFQLIHSAKKLHQAGIKFKPRETDSFLDIEFSNGVLEIPLLTIDDFITSVILNCVAFEQCYNHCSNHITSYVTFMGCLINAPSDAGFLCDYKIVENSFGADEEVASFFNNIGKDVTFDTQWSYLSKVFEDVNEHYSNNWQVRWAEFKHTYFDTTWSFISALAAVVLLILTMIQAFFAFY 450          

Query:   43 NNGGRDGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFES-VDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGP 1410
            +  G+  D VI +++      ++  +S+E+ +  + K   LL  +AG  SCCIF+VP+ L ++N + Y PHIVSIGPYHHG    +M+++HKWR+L  +L RT     +L D+ + +A KEE+IR CYSE    S  +L++MM++DG FIIE+   V RL +       DD IFN               ENQIPFFVLE LF     +    D   SL++ +L+FF++AV +R  E L+++    G HLLDL R T+I      P  +A+   +  I+S KKL  +GIKFK     SFLDI F +GVL +P +TVDD      LN VAFEQCY HC KHIT+Y  FM CL  TPAD  +L D  IIENY G+D+EV  FF ++GKD  FDI  SYL +LFKDVN++  N ++++WAGF  TYFD+PWSFMSA A LI L+LT IQ   A+Y    P
Sbjct:   13 HENGKTSDHVIAIST----EASEWLASLEDKISKMPK---LLNKTAGKSSCCIFRVPKSLAQINEKAYQPHIVSIGPYHHGNDQFQMIEEHKWRFLGAVLTRTKAKDISLDDFFKAIAPKEEEIRECYSENIGYSSHQLIEMMILDGCFIIELLCIVARLVQ----THLDDPIFNMAWMFSFLMRDLLRLENQIPFFVLESLFGLVSVTLD--DSSRSLTELALEFFDYAV-ERPAEFLDRFKDKKGKHLLDLFRSTFIPPPQGKPNEDAYSPFLQLIQSAKKLRLSGIKFKPKRTDSFLDISFSHGVLRIPPLTVDDFTSSFLLNCVAFEQCYKHCSKHITSYVTFMGCLINTPADAGYLSDHRIIENYFGTDDEVAKFFNDVGKDITFDIQRSYLSKLFKDVNKYYRNNFHIKWAGFKHTYFDSPWSFMSAMAALILLVLTIIQAFFAVYPYASP 455          

Query:   58 DGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHD------IPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            + DVV+++   +   + ++   + E  +       LLR SAG  SCCIF+VP+ LVE+N ++Y PHI+SIGPYH G+P L+M+++HKW YL  L+ART   G  L DYL+ +   E + R CYSE   L   + ++M+V+DG FII+ F ++ ++       +PDD + +               ENQ+PFFVL+ LF+ +K   P  +   SL+   L FFN   LQR DE L+K+ +L G H LDL+R ++I +      + H P          I+ V KL +AGIK K G+A SFL +KFRNGV+E+P +T+DD     F N VAFE C+  C KHITTYA  ++CL  T  D   LC+RNI ENY G+D  V  F  NLGKD  FD +  YL +LF DVNE+ +N W+VQ AG   TYFDTPWSF+SA A  I LLLT +QT   +Y
Sbjct:    5 NNDVVVRIWEVNKERLARMQQKISEEPR-------LLRKSAGRSSCCIFRVPRTLVEINSRSYQPHIISIGPYHRGEPHLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMEARECYSEIIHLDTHDFLEMLVLDGCFIIDFFRKIGKMHP----FEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTK--MPGEESGPSLASLVLGFFN-NTLQRPDEILQKHCNLKGKHFLDLLRLSFIPEEQELGTLDHRP-------THLIQCVSKLRKAGIKLKSGKADSFLTVKFRNGVMEMPPVTIDDFLTCFFQNCVAFELCHKDCTKHITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVY 435          

Query:   58 DGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHD------IPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            + DVV+++   +   + ++   + E  +       LLR SAG  SCCIF+VP+ LVE+N ++Y PHI+SIGPYH G+P L+M+++HKW YL  L+ART   G  L DYL+ +   E   R CYSE   L   + ++M+V+DG FII+ F ++ ++       +PDD + +               ENQ+PFFVL+ LF+ +K   P  +   SL+   L FFN   LQR DE L+K+ +L G H LDL+R ++I +        H P          I+ V KL +AGIK K G+A SFL +KFRNGV+E+P +T+DD     F N VAFE C+  C KHITTYA  ++CL  T  D   LC RNI ENY G+D  V     NLGKD  FD +  YL +LF DVNE+  N W+VQ AG   TYFDTPWSF+SA A  I LLLT +QT   +Y
Sbjct:    5 NNDVVVRIWEVNKERLARMQQKISEEPR-------LLRKSAGRSSCCIFRVPRTLVEINSRSYQPHIISIGPYHRGEPXLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMXARECYSEIIHLXTHDFLEMLVLDGCFIIDFFRKIGKMHP----FEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTK--MPGEESGPSLASLVLGFFN-NTLQRPDEILQKHCNLKGKHXLDLLRLSFIPEEQELGTXDHXP-------THLIQCVSKLRKAGIKLKSGKADSFLTVKFRNGVMEMPPVTIDDFLXCFFQNCVAFELCHKDCTKHITTYATLLDCLINTSKDVGXLCXRNIFENYFGTDAXVARXINNLGKDVTFDPDNCYLSKLFNDVNEYYXNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVY 435          

Query:  163 LLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAA-SFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            LL  +A   SCCIFKVPQ  +++NG++Y PH+VSIGPYHHG+  L+M+++HKWRYL  +L+RT   G  L   L+ +   E+  R CYS+       E ++MMVVDG FIIE+F +V  + E     + DD I                 ENQIPFFVLE LF+ ++   P  +   SL K SL FFN+A LQR D  + ++  L   HLLDL+R ++I D       +   S   I SV KL +AGI+  +G    SFL +KF+NGV+E+P +T+D+      LN VAFEQC+N   KH TTYA  ++CL  T  D   L D NIIENY G+D EV  F  +LGK+ AFDI   YL  LF DV+++  N  +VQWA F  TYF TPWSF+SA A LI LLLT  QTV  IY +
Sbjct:   11 LLTKAAANSSCCIFKVPQRFIDINGKSYQPHVVSIGPYHHGEEHLKMIEEHKWRYLGSILSRTQNKGLDLEVLLKAIQPLEKKARECYSQIIHFDTDEFIEMMVVDGCFIIELFRKVGNVVE----FEVDDPIVTMAWIIPFFYRDLLRLENQIPFFVLECLFDITR--MPGEESGPSLCKLSLDFFNYA-LQRPDNIIARHNDLNAKHLLDLVRSSFI-DFEQGQSLHVDTSTPMIHSVSKLRRAGIELSQGNPEDSFLVVKFKNGVIEMPTITIDETVTSFLLNCVAFEQCHNGSSKHFTTYATLLDCLVNTFKDVEHLSDCNIIENYFGTDSEVASFINDLGKEVAFDIERCYLSSLFHDVDQYYKNSRHVQWASFKYTYFSTPWSFVSALAALIILLLTVSQTVYTIYGT 416          

Query:  163 LLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAA-SFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            LL  +A   SCCIFKVPQ  +++NG++Y PHIVSIGPYHHG+  L M+++HKW YL  +L+RT   G  L   L+ +   E   R CYS+   L   E V+MMV+DG+FIIE+F +V  +       + DD I                 ENQIPFFVLE LF  ++   P  +   SLSK +L FFN A LQR D  + ++ +    HLLDL+R ++I      PR     S   I+SV KL +AGIK  +G+ A SFL +KF+NGV+E+P +T+DD      LN VAFEQC++    H TTYA  ++CL  T  D  +LCD NIIENY G+D EV  F  +LGK+ AFDI   YL ++F DV+++  + W++QWA F  TYF TPWSF+SA A LI LLLT  QT   IY +
Sbjct:   11 LLTKAAANSSCCIFKVPQRFIDINGKSYQPHIVSIGPYHHGEAHLRMIEEHKWGYLGSMLSRTQNNGLDLEVLLRAIQPLEMKARECYSQIIHLDTCEFVEMMVLDGVFIIELFRKVGEIVG----FEADDPIVTMAWIIPFFYRDLLRLENQIPFFVLECLFEITRT--PGEESGPSLSKLALDFFNNA-LQRPDYIIARHNNGKAKHLLDLVRSSFIDSEQAQPRC-VDTSTPMIQSVSKLRRAGIKLGQGDPADSFLVVKFKNGVIEMPTITIDDTISSFLLNCVAFEQCHSGSSNHFTTYATLLDCLINTIKDVEYLCDCNIIENYFGTDSEVARFVNDLGKEVAFDIERCYLSEMFSDVHQYYKDRWHLQWASFKFTYFSTPWSFISAMAALIILLLTVAQTFYTIYGT 416          

Query:  136 LKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI--HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKG-EAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQT 1380
            LK  E   +L + +AG RSCCIF+VPQ LVEVNG+ Y P IVSIGPYH  +P L M+++HKWRYL  LL+RT   G  L D  + +A  E + R CYSET  L   + +QMM++DG FIIE+F +V RL       + +D +                 ENQIPFF+L  L+  +K   P      +LS  +L FFN + LQ+ DE L+    + G HLLDL+R ++I  +D    PR         I  V KL +AGIK     E+ SFL++KFR GV+E+P +TVDD      LN VA EQCY+ C KH T Y   ++CL  T  D  +LCDRN++EN+LG++ EV  F  N GKD A D++  YL  LF DV+++  N W+VQWA F  TYFDTPWSF+S  A  I LLLT  QT
Sbjct:    3 LKISENPKFLCK-AAGKRSCCIFRVPQSLVEVNGKAYQPRIVSIGPYHRNQPRLNMIEEHKWRYLGSLLSRTNTIGFVLEDLFKAIAPLESEARECYSETINLDSHDFIQMMILDGCFIIELFRKVARLVP----FEREDPLLTMVWILPFFYRDFLKLENQIPFFILNQLYQVTK--LPGEKSTPTLSTLALLFFNNS-LQKPDESLQN--DVQGKHLLDLVRSSFIPKNDEETEPRKRVMTPTHVILCVSKLRRAGIKINPSKESESFLNVKFRRGVIEMPSLTVDDFMSSFLLNCVALEQCYSGCSKHFTAYITLLDCLVNTYRDVEYLCDRNVVENHLGTEGEVASFINNAGKDVAVDLDLCYLSLLFNDVHKYYINSWHVQWASFKHTYFDTPWSFISLLAASILLLLTVAQT 410          

Query:  124 MEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI-----HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKK-GEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            M E LK   +   LL  +AG  +C IF+VPQ +++ NG+ Y P +VS+GP+H G+  LEM+Q+HKWRYL  LL RT     TL DY++ V   EE+ R CYSET  +   E  +MMV+DG F++E+F +V  L       +P+D +                 ENQIPFFVLE LF+ ++    N +  +SL   +  FFN  ++ R+DEDL ++  L   HLLDL+R ++I     H  P    G        I S+ KL +AGIK ++  +A SFL ++FR+G +E+P +TVDD       N VA+EQC+  C  H TTYA  ++CL  T  D  +LCD+NIIENY G+D E+  F  +LG+D AFDI   YL  LF++VNE+  + W+V+WA F  TYF++PWSF+SA A L+ L+L+ IQTV  ++
Sbjct:   28 MHEKLKEPPR---LLSSAAGKPTCSIFRVPQSMIDCNGRWYEPRVVSVGPFHRGQIRLEMIQEHKWRYLNVLLTRTQNL--TLEDYMKSVKSVEEEARECYSETIHMDSEEFNEMMVLDGCFLLELFRKVNNLVP----FEPNDPLVAMAWVLPFFYRDFLCLENQIPFFVLETLFDLTRGDNKN-ETNASLPSLAFAFFN-NMMHRTDEDLARFKELRAKHLLDLLRSSFIPESQLHTPPETNPGKEKTPSHIIHSISKLRRAGIKLRELKDAESFLVVRFRHGAIEMPAITVDDFMSSFLENCVAYEQCHVACSMHFTTYATLLDCLTNTYKDVEYLCDQNIIENYFGTDTELARFVNSLGRDVAFDITQCYLKDLFEEVNEYYKSSWHVEWATFKFTYFNSPWSFVSALAALVLLVLSVIQTVYTVF 446          

Query:  124 MEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI-----HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKK-GEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            +E   K +++   LL  +AG  +C IF+VPQ +++ NG+ Y P +VSIGPYH G+  L+M+++HKWRYL  LL RT     TL DY++ V   EE  R CYSET  +   E  +MMV+DG F++E+F +V  L       +P+D +                 ENQIPFFVLE LFN ++    N +  +SL   +  FFN  ++ R++EDL ++  L   HLLDL+R ++I     H  P    G        I S+ KL +AGIK ++  +A SFL ++FR+G +E+P +TVDD       N VA+EQC+  C  H TTYA  ++CL  T  D  +LCD+NIIENY G+D E+  F  +LG+D AFDI   YL  LF++VNE+  + W+V+WA F  TYF++PWSF+SA A L+ L+L+ IQT+  ++
Sbjct:   22 IERMHKKLKEPPRLLSSAAGKPTCSIFRVPQSMIDCNGRCYEPRVVSIGPYHRGQTQLKMIEEHKWRYLNVLLTRTQNL--TLEDYMKSVKNVEEVARECYSETIHMDSEEFNEMMVLDGCFLLELFRKVNNLVP----FEPNDPLVAMAWVLPFFYRDFLCLENQIPFFVLETLFNLTRGDNEN-ETNASLQSLAFAFFN-NMMHRTEEDLARFKELRAKHLLDLLRSSFIPESELHTPPATNPGKEKMPSHIIHSISKLRRAGIKLRELKDAESFLVVRFRHGTIEMPAITVDDFMSSFLENCVAYEQCHVACSMHFTTYATLLDCLTNTYKDVEYLCDQNIIENYFGTDTELAKFVNSLGRDVAFDITQCYLKDLFEEVNEYYKSSWHVEWATFKFTYFNSPWSFVSALAALVLLVLSVIQTIYTVF 443          

Query:  124 MEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI-----HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKK-GEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            +E   K +++   LL  +AG  +C IF+VPQ +++ NG+ Y P +VSIGPYH G+  L+M+++HKWRYL  LL RT     TL DY++ V   EE  R CYSET  +   E  +MMV+DG F++E+F +V  L       +P+D +                 ENQIPFFVLE LFN ++    N +  +SL   +  FFN  ++ R++EDL ++  L   HLLDL+R ++I     H  P    G        I S+ KL +AGIK ++  +A SFL ++FR+G +E+P +TVDD       N VA+EQC+  C  H TTYA  ++CL  T  D  +LCD+NIIENY G+D E+  F  +LG+D AFDI   YL  LF++VNE+  + W+V+WA F  TYF++PWSF+SA A L+ L+L+ IQT+  ++
Sbjct:   22 IERMHKKLKEPPRLLSSAAGKPTCSIFRVPQSMIDCNGRCYEPRVVSIGPYHRGQTQLKMIEEHKWRYLNVLLTRTQNL--TLEDYMKSVKNVEEVARECYSETIHMDSEEFNEMMVLDGCFLLELFRKVNNLVP----FEPNDPLVAMAWVLPFFYRDFLCLENQIPFFVLETLFNLTRGDNEN-ETNASLQSLAFAFFN-NMMHRTEEDLARFKELRAKHLLDLLRSSFIPESELHTPPATNPGKEKMPSHIIHSISKLRRAGIKLRELKDAESFLVVRFRHGTIEMPAITVDDFMSSFLENCVAYEQCHVACSMHFTTYATLLDCLTNTYKDVEYLCDQNIIENYFGTDTELAKFVNSLGRDVAFDITQCYLKDLFEEVNEYYKSSWHVEWATFKFTYFNSPWSFVSALAALVLLVLSVIQTIYTVF 443          

Query:  130 ESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTY--------IHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFK-KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYA 1398
            +SL S +    LLR SAG   CCI ++PQ L  +N + Y P IVSIGPYHHGK  L+M QQHK R+L+  +A+    G    + ++ V+  E  IRG YSE   L    LVQMMV+DG FI+ +FF V   S +    + DD IF                ENQ+P+ +L+ LF  SK     C   S L++ + +FFN++ LQ+ +   EK+Y L   HLLDLIRKT+        I D       N  E +  + S KKLH  GIKFK +    S LDI + NGVL +P + +DD    +FLN VAFEQ Y     HIT+Y  FM CL    +D SFL +R I+ENY G+++EV+ F+K +GKD A D+  SYL ++F+ VNE+ +  ++V  A F+ T+FD+PW+F S+ A L+ LL  A+Q   A Y+
Sbjct:   10 KSLISEDNGLKLLRESAGSELCCIVRIPQSLARINLKAYEPKIVSIGPYHHGKEHLKMTQQHKRRFLKFFVAKMEEKGFVPQELVKAVSSLEGVIRGSYSEDLGLDSENLVQMMVLDGCFILTLFFVV---SGKVEYTNLDDPIFRMPWILPSIRADLLLLENQVPYVLLQTLFETSK--LVTC---SGLNEIAFEFFNYS-LQKPETFWEKHYGLEAKHLLDLIRKTFVPVPSQRRIKDHSSKSSFNDHEYLGFVLSAKKLHLRGIKFKPRKNTDSILDISYSNGVLHIPPVVMDDFTASIFLNCVAFEQLYADSSNHITSYVAFMACLINEESDASFLSERRILENYFGTEDEVSRFYKRIGKDIALDLEKSYLAKVFEGVNEYTSQGFHVHCAEFIHTHFDSPWTFASSFAALLLLLFAALQVFFAAYS 432          

Query:  166 LRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHG--KPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSK--PSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIH-----------------------------------------------DIPHPPRGNAFESVDKIRSVKKLHQAGIKF-KKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYA 1398
            L+ SAG R CCI+++P  L +VN + Y P IVSIGPYHH   K  L+M+++HK RYL   +++T   G  L   + LV+  E+ IR  YSE  + S+ +L+++M++DG FI+ +F  V +  E     DP   IF                ENQ+P F+L++L   SK  PS       +SL+  + KFF++++ ++ +   EK+ +L   HLLDLIRKT+I                                                  P PP    F  +  I S +KL   GIKF +K    + LDI F++G++E+P +  DD   +L +N VAFEQ    C   IT++ +FM CL  T  D +FL ++ I+ENY G+ EEV+ FFKN+GKD +F I+ S+L  +F+ VNE+ +  ++V WAGF  T+F+TPW+F+S+ A L+ LLLT  Q   A YA
Sbjct:   35 LKESAGDRFCCIYRIPHTLKQVNDKAYAPKIVSIGPYHHSSDKQHLKMIEEHKKRYLEMFVSKTKENGVYLIHLVDLVSGLEQKIRDSYSENLEFSQQKLIKVMLLDGCFILMLFLVVSQKIEYTNLKDP---IFKLRWILPTLRSDLLLLENQVPLFLLKVLLETSKLAPS-------TSLNMLAFKFFDYSI-KKPEGFWEKHNNLRAKHLLDLIRKTFIPAPPPSTTPRQCCINIFNGPREYSRTETSKNICLGKISCSKEITGAQTSSPPPPPRRPFLGL--IVSARKLRLRGIKFMRKENVETPLDISFKSGLVEIPLLVFDDFISNLLINCVAFEQFNMSCSTEITSFVIFMGCLINTEDDATFLIEKGILENYFGTGEEVSLFFKNIGKDISFSISKSFLSNVFEGVNEYTSQGYHVHWAGFKYTHFNTPWTFLSSCAALVLLLLTIFQAFFAAYA 484          

Query:  112 LTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIP-------------HPPRGNAFE------SVDKIRSVKKLHQAGIKFK-KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFL-CDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            + S ++ +L+S  K   LL  SAG  SCCIF++P  L EVN + Y P +VSIGPYH+G+  L+M+QQHK+R+L   + R    G         V   +  IR  YSE  ++ KSELV MM++DG FI+ +   V R  + D   DP   IF                ENQ+PFFVL  +F++S    P       L++ +  FFN ++  + D    K+   G  HLLDL RKT+I  +                 +G + E      +   I S K+L   GIKF+ + +A S LDIK +   L++P + +D     +FLN VAFEQ Y      IT+Y VFM CL     D +FL  D+ IIENY G++ EV+ FFK + KD  FD   SYL  +F+ VNE+ +  +N  WAGF  T+F++PW+ +S+ AV+  +LLT  Q   AI
Sbjct:   35 VVSHIKRNLQSSGKPLILLE-SAGKASCCIFRIPDSLAEVNPKAYKPKVVSIGPYHYGENHLQMIQQHKFRFLELFVDRATKKGMDENVLYAAVGALQHKIRASYSEELRIEKSELVSMMILDGCFILMLLLIVSRKIDLDMNKDP---IFTIPWILASIQSDLLLLENQVPFFVLRTIFDKSGIGSP-----GDLNRMAFSFFNLSI-DKPDTYWAKHRDRGAKHLLDLNRKTFIPSMRSMGESETTPSSKFQHSKGKSGEVSSSESTFPLILSAKRLRLQGIKFRLRSDAESILDIKLKKNKLQIPLLRLDGFISSIFLNCVAFEQFYTESTNDITSYVVFMGCLLNDQEDATFLNNDKRIIENYFGNENEVSQFFKTICKDVVFDTRRSYLRNVFEGVNEYTSKTYNGVWAGFRHTHFESPWTALSSFAVVFVILLTMTQAAYAI 472          

Query:  112 LTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIP-------------HPPRGNAFE------SVDKIRSVKKLHQAGIKFK-KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFL-CDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            + S ++ +L+S  K   LL  SAG  SCCIF++P  L EVN + Y P +VSIGPYH+G+  L+M+QQHK+R+L   + R    G         V   +  IR  YSE  ++ KSELV MM++DG FI+ +   V R  + D   DP   IF                ENQ+PFFVL  +F++S    P       L++ +  FFN ++  + D    K+   G  HLLDL RKT+I  +                 +G + E      +   I S K+L   GIKF+ + +A S LDIK +   L++P + +D     +FLN VAFEQ Y      IT+Y VFM CL     D +FL  D+ IIENY G++ EV+ FFK + KD  FD   SYL  +F+ VNE+ +  +N  WAGF  T+F++PW+ +S+ AV+  +LLT  Q   AI
Sbjct:   35 VVSHIKRNLQSSGKPLILLE-SAGKASCCIFRIPDSLAEVNPKAYKPKVVSIGPYHYGENHLQMIQQHKFRFLELFVDRATKKGMDENVLYAAVGALQHKIRASYSEELRIEKSELVSMMILDGCFILMLLLIVSRKIDLDMNKDP---IFTIPWILASIQSDLLLLENQVPFFVLRTIFDKSGIGSP-----GDLNRMAFSFFNLSI-DKPDTYWAKHRDRGAKHLLDLNRKTFIPSMRSMGESETTPSSKFQHSKGKSGEVSSSESTFPLILSAKRLRLQGIKFRLRSDAESILDIKLKKNKLQIPLLRLDGFISSIFLNCVAFEQFYTESTNDITSYVVFMGCLLNDQEDATFLNNDKRIIENYFGNENEVSQFFKTICKDVVFDTRRSYLRNVFEGVNEYTSKTYNGVWAGFRHTHFESPWTALSSFAVVFVILLTMTQAAYAI 472          

Query:  112 LTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIP-------------HPPRGNAFE------SVDKIRSVKKLHQAGIKFK-KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFL-CDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            + S ++ +L+S  K   LL  SAG  SCCIF++P  L EVN + Y P +VSIGPYH+G+  L+M+QQHK+R+L   + R    G         V   +  IR  YSE  ++ KSELV MM++DG FI+ +   V R  + D   DP   IF                ENQ+PFFVL  +F++S    P       L++ +  FFN ++  + D    K+   G  HLLDL RKT+I  +                 +G + E      +   I S K+L   GIKF+ + +A S LDIK +   L++P + +D     +FLN VAFEQ Y      IT+Y VFM CL     D +FL  D+ IIENY G++ EV+ FFK + KD  FD   SYL  +F+ VNE+ +  +N  WAGF  T+F++PW+ +S+ AV+  +LLT  Q   AI
Sbjct:   35 VVSHIKRNLQSSGKPLILLE-SAGKASCCIFRIPDSLAEVNPKAYKPKVVSIGPYHYGENHLQMIQQHKFRFLELFVDRATKKGMDENVLYAAVGALQHKIRASYSEELRIEKSELVSMMILDGCFILMLLLIVSRKIDLDMNKDP---IFTIPWILASIQSDLLLLENQVPFFVLRTIFDKSGIGSP-----GDLNRMAFSFFNLSI-DKPDTYWAKHRDRGAKHLLDLNRKTFIPSMRSMGESETTPSSKFQHSKGKSGEVSSSESTFPLILSAKRLRLQGIKFRLRSDAESILDIKLKKNKLQIPLLRLDGFISSIFLNCVAFEQFYTESTNDITSYVVFMGCLLNDQEDATFLNNDKRIIENYFGNENEVSQFFKTICKDVVFDTRRSYLRNVFEGVNEYTSKTYNGVWAGFRHTHFESPWTALSSFAVVFVILLTMTQAAYAI 472          

Query:  163 LLRPSAGMRSCCIFKVPQWLVEVNGQT-YHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHP----------------------------------------------PRGNAFESVDK---------IRSVKKLHQAGIKFK-KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHK-HITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            LLR SAG + CCIFK+         +  Y P +VS+GPYHHGK +L+M+++HK R+L+  +      G      ++ V+  EEDIR  YSE+      +L++MMV+DG FI+ IF  V  +         +D IF                ENQ+PFF+L+ +F++SK      ++ S L++    FFN++ LQ+S+    K+  +   HLLDLIR  Y+ D+P                                                P+ ++ E  D          + S +KL   GIKFK + +A + +DI+ +  +L++P + +DD  + + LN VAFEQ Y++C K H+T+Y  FM CL  + AD  FL +  I+ENY GS +EV+ FFK +GKD  FDI+ SYL  +F+ VN++ ++ W+VQWAGF  T+FD+PW+ +S+ A L  ++LT IQ   A Y
Sbjct:   37 LLRESAGGKKCCIFKISHKPENKKYKAAYEPRVVSLGPYHHGKKNLQMIEEHKLRFLKIFMDEAKRKGVDTNGLIKAVSVLEEDIRDSYSESLYSDGKKLIEMMVLDGCFILMIFLVVAGVVSHSEI--ENDPIFAIPWILPAIRNDLILLENQVPFFLLQTIFDRSK-----IEKSSGLNEIIFHFFNYS-LQKSNTFWLKHQKVEANHLLDLIRNIYMPDVPKEEKKSNHLLDCMMIRKICMPRESKQELDVMLKKGKQEVDISMLEEGIPKSDSLEEEDSTTGRHHLKMVLSARKLQLKGIKFKARKKAETLMDIRHKGKLLQIPPLILDDFLIAVLLNCVAFEQYYSYCTKQHMTSYVAFMGCLLKSEADAMFLSEVGILENYFGSGDEVSRFFKVVGKDVLFDIDESYLAGIFEGVNKYTSSGWHVQWAGFKHTHFDSPWTALSSCAALTLVILTIIQAFFAAY 497          

Query:  118 SSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIP--------------HPPRGNAFESVDK-----IRSVKKLHQAGIKFK--KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLC-DRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI--YASDGPG 1413
            S+    L S  K   LL  SAG  SCCIF+VP+  V +N + Y P +VSIGPYH+G+  L+M+QQHK R L+  L             ++ V   E+ IR  YSE  K    +L+ MMV+DG FI+ +F  +    E       +D IF+               ENQ+PFFVL+ L+  SK         S L++ +  FF   +  +     EK+ +    HLLDLIR+T++ +                H  +     SVD      I S K+L   GIKF+  + +  S L+++ +   L++PQ+  D      FLN VAFEQ Y      ITTY VFM CL     D +FL  D+ IIEN+ GS+ EV+ FFK + KD  F+++ SYL  +FK VNE+    +N  WAGF  T+F++PW+F+S+ AVL  +LLT +Q+ +AI  Y +D  G
Sbjct:   21 SAFRNYLSSGSKEPVLLLESAGKESCCIFRVPESFVALNPKAYKPKVVSIGPYHYGEKHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGH-DLMFMMVLDGCFILMVFLIMSGNIELS-----EDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSK-----IGVSSDLNRIAFHFFKNPI-DKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQFYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDKKG 464          

Query:  118 SSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIP--------------HPPRGNAFESVDK-----IRSVKKLHQAGIKFK--KGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLC-DRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI--YASDGPG 1413
            S+    L S  K   LL  SAG  SCCIF+VP+  V +N + Y P +VSIGPYH+G+  L+M+QQHK R L+  L             ++ V   E+ IR  YSE  K    +L+ MMV+DG FI+ +F  +    E       +D IF+               ENQ+PFFVL+ L+  SK         S L++ +  FF   +  +     EK+ +    HLLDLIR+T++ +                H  +     SVD      I S K+L   GIKF+  + +  S L+++ +   L++PQ+  D      FLN VAFEQ Y      ITTY VFM CL     D +FL  D+ IIEN+ GS+ EV+ FFK + KD  F+++ SYL  +FK VNE+    +N  WAGF  T+F++PW+F+S+ AVL  +LLT +Q+ +AI  Y +D  G
Sbjct:   21 SAFRNYLSSGSKEPVLLLESAGKESCCIFRVPESFVALNPKAYKPKVVSIGPYHYGEKHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGH-DLMFMMVLDGCFILMVFLIMSGNIELS-----EDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSK-----IGVSSDLNRIAFHFFKNPI-DKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQFYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDKKG 464          

Query:  196 CIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFF-RVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFN--------------FAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFES-------VDK-----IRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYA 1398
            CI++VP +L E + ++Y P  VS+GPYHHGK  L  M++HKWR L  +L R       +  Y   +   EE  R CY     LS++E  +M+V+DG F++E+F   VE  +E       +D +F                ENQ+P FVL+ L      ++   ++   ++  ++KFF+                ++   ++ L+     G +H LD+ R++ +   P P   +  +        VDK     +  V +L +AG+KF+K +   F DI+F+NG LE+P++ + D    LF N +AFEQC+     HIT+Y +FM+ L  +  D S+L    IIE++LGSD EV   F  L ++  FD   S+L +L  DVN + N  WNV  A     YF+ PW++ S SA +I LLLT  Q+  A+YA
Sbjct:  114 CIYRVPHYLQENDKKSYFPQTVSLGPYHHGKKRLRPMERHKWRALNKVLKRLKQR---IEMYTNAMRELEEKARACYEGPISLSRNEFTEMLVLDGCFVLELFRGTVEGFTEIGYA--RNDPVFAMRGLMHSIQRDMIMLENQLPLFVLDRLLELQLGTQ---NQTGIVAHVAVKFFDPLMPTGEALTKPDQSKLMNWLEKSLDTLGDKGELHCLDVFRRSLLQSSPTPNTRSLLKRLTRNTRVVDKRQQQLVHCVTELREAGVKFRKRKTDRFWDIEFKNGYLEIPKLLIHDGTKSLFSNLIAFEQCHIESSNHITSYIIFMDNLINSSEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDPKDSHLSRLSGDVNRYYNRKWNVLKATLTHKYFNNPWAYFSFSAAVILLLLTLCQSFYAVYA 533          

Query:  100 NITQLTSSMEESLKSVE-KTDWL---LRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            ++T +T +  + LKSVE KT  L   L  SAG  SCCIF+VPQ L E+N   Y PHIVSIGPYHHGK  L+M+++HKWR+L  +LART   G  + D+ + +A  EE IR CYSET + S+ E ++MMV+DG FIIE+F  V  + +     D DD IFN               ENQIPFFVLE LF  S  S       SS ++ +L+FF++A  QR  E L +Y  + G HLLDL R T I      P G     +  I+S KKLHQAGIKFK  E  SFLDI+F NGVLE+P +TVDD    + LN VAFEQCYNHC  HIT+Y  FM CL   P+D  FLCD  I+ENY G+DEEV  FF N+GKD  FDI  SYL ++F+DVNEH +N W+V+WAGFM TYFDTPWSF+SA A ++ L+LT IQ   A Y
Sbjct:   38 HVTSITEADRQWLKSVETKTKLLPKLLNNSAGKSSCCIFRVPQSLFEINKMAYQPHIVSIGPYHHGKVHLKMIEEHKWRFLGGVLARTQQHGIGINDFFKAIAPIEEKIRDCYSETIECSRQEFIEMMVLDGCFIIELFCIVGGIVQ----TDIDDPIFNMTRMFFFIMRDLLRLENQIPFFVLETLFETSILSSRK-QNVSSFAELALEFFDYAA-QRPPEVLRRYKDIRGKHLLDLFRSTIIPSSQEVP-GKISPFLQLIQSAKKLHQAGIKFKPRETDSFLDIEFSNGVLEIPLLTVDDFTTSVILNCVAFEQCYNHCSNHITSYVTFMGCLINAPSDAGFLCDYKIVENYFGTDEEVARFFNNVGKDVTFDIQRSYLSKVFEDVNEHYSNNWHVRWAGFMHTYFDTPWSFISALAAVVLLILTMIQAFFAFY 466          

Query:  163 LLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAA-SFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            LL  +A   SCCIFKVPQ  +++NG++Y PHIVSIGPYHHG+  L M+++HKW YL  +L+RT   G  L   L+ +   E   R CYS+   L   E V+MMV+DG+FIIE+F +V  +       + DD I                 ENQIPFFVLE LF  ++   P  +   SLSK +L FFN A LQR D  + ++ +    HLLDL+R ++I      PR     S   I+SV KL +AGIK  +G+ A SFL +KF+NGV+E+P +T+DD      LN VAFEQC++    H TTYA  ++CL  T  D  +LCD NIIENY G+D EV  F  +LGK+ AFDI   YL ++F DV+++  + W++QWA F  TYF TPWSF+SA A LI LLLT  QT   IY +
Sbjct:   11 LLTKAAANSSCCIFKVPQRFIDINGKSYQPHIVSIGPYHHGEAHLRMIEEHKWGYLGSMLSRTQNNGLDLEVLLRAIQPLEMKARECYSQIIHLDTCEFVEMMVLDGVFIIELFRKVGEIVG----FEADDPIVTMAWIIPFFYRDLLRLENQIPFFVLECLFEITRT--PGEESGPSLSKLALDFFNNA-LQRPDYIIARHNNGKAKHLLDLVRSSFIDSEQAQPRC-VDTSTPMIQSVSKLRRAGIKLGQGDPADSFLVVKFKNGVIEMPTITIDDTISSFLLNCVAFEQCHSGSSNHFTTYATLLDCLINTIKDVEYLCDCNIIENYFGTDSEVARFVNDLGKEVAFDIERCYLSEMFSDVHQYYKDRWHLQWASFKFTYFSTPWSFISAMAALIILLLTVAQTFYTIYGT 416          

Query:   61 GDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLL----RPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEI-FFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            GD   + A     ++T +T +  + LKSVEK   LL    + SAG  SCCIF+VPQ LVE+N + YHPHIVSIGPYHHGK  L+M+++HKWR+L  +LART   G                               +VQ  + D +F + + FF + R                               ENQIPFFVLE LF  S  S       SSL++ +LKFF+ A  +R  E L +Y  + G HLLDL R T I                 I S KKLHQAGIKFK  E  SFLDI+F NGVLE+P +T+DD    + LN VAFEQCYNHC  HIT+Y  FM CL   P+D  FLCD  I+EN  G+DEEV  FF N+GKD  FD   SYL ++F+DVNEH +N W V+WA F  TYFDT WSF+SA A ++ L+LT IQ   A Y
Sbjct:    9 GDQSQENAETSNDHVTSITEADRQWLKSVEKKTKLLPKLLKKSAGKSSCCIFRVPQSLVEINKKAYHPHIVSIGPYHHGKVHLKMIEEHKWRFLGGVLARTQQHG-------------------------------IVQRDIDDPIFNMTLMFFFIMR--------------------------DLLKLENQIPFFVLETLFETSILSSRK-QIVSSLTELALKFFDHAA-ERPPEVLRRYKDIRGEHLLDLFRSTIIPASSQEVH-RKISPFQLIHSAKKLHQAGIKFKPRETDSFLDIEFSNGVLEIPLLTIDDFITSVILNCVAFEQCYNHCSNHITSYVTFMGCLINAPSDAGFLCDYKIVENSFGADEEVASFFNNIGKDVTFDTQWSYLSKVFEDVNEHYSNNWQVRWAEFKHTYFDTTWSFISALAAVVLLILTMIQAFFAFY 398          

Query:   52 GRDGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            G D  + I   + D +N+      M + +    K   LL  +A   SCCIFKVPQ  +++NG++Y PH+VSIGPYHHG+  L+M+++HKWRYL  +L+RT   G  L   L+ +   E+  R CYS+       E ++MMVVDG FIIE+F +V  + E     + DD I                 ENQIPFFVLE LF+ ++   P  +   SL K SL FFN+A LQR D  + ++  L   HLLDL+R ++I D       +   S   I S+ + +            SFL +KF+NGV+E+P +T+D+      LN VAFEQC+N   KH TTYA  ++CL  T  D   L D NIIENY G+D EV  F  +LGK+ AFDI   YL  LF DV+++  N  +VQWA F  TYF TPWSF+SA A LI LLLT  QTV  IY +
Sbjct:   17 GNDHVIRIWEVNEDRLNL------MHQKISDPPK---LLTKAAANSSCCIFKVPQRFIDINGKSYQPHVVSIGPYHHGEEHLKMIEEHKWRYLGSILSRTQNKGLDLEVLLKAIQPLEKKARECYSQIIHFDTDEFIEMMVVDGCFIIELFRKVGNVVE----FEVDDPIVTMAWIIPFFYRDLLRLENQIPFFVLECLFDITR--MPGEESGPSLCKLSLDFFNYA-LQRPDNIIARHNDLNAKHLLDLVRSSFI-DFEQGQSLHVDTSTPMIHSLSQGNPED---------SFLVVKFKNGVIEMPTITIDETVTSFLLNCVAFEQCHNGSSKHFTTYATLLDCLVNTFKDVEHLSDCNIIENYFGTDSEVASFINDLGKEVAFDIERCYLSSLFHDVDQYYKNSRHVQWASFKYTYFSTPWSFVSALAALIILLLTVSQTVYTIYGT 440          

Query:  121 SMEESLKSVEKTDWLLRPSAGMRS-CCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEK------------------YYHLGGVHLLDLIRKTYIHDIPHPP-------RGNAFESVDK-----IRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYA 1398
            S++E LK   + D     +AG  S   I++VP++L E + + Y P I+S+GPYHHGK  L  M QHKWR L  ++ RT      +  YL  V   EE  R CY     LS +E V+MMV+DG F++E+F  V     +      +D +F                ENQ+P FVL+ L         N D+   +++ +L FF+   L  +DE L K                      GG+H LD+ R++ +   P P        R NA    DK     I  V +L +AGIK +K +   F D+KF+ G+L VP++ + D    LFLN +A EQC+  C   IT++ +FM+ L  +P D ++L    IIE++LGSD +V   F  L ++  FDIN SYL +L +DVN + N+ WN   A     YF  PW+ +S  A ++ LLLT  QT   +YA
Sbjct:   85 SIKEKLKEAGQED-----AAGSWSKLSIYRVPRYLREGDDKAYVPQIISLGPYHHGKKRLRQMDQHKWRCLHRVIKRT---NQDIKLYLDAVREIEEKARSCYEGPINLSSNEFVEMMVLDGCFVLELFRGVAE-GFKKLGYPRNDPVFAMRGSMHSIQRDMIMLENQLPLFVLDRLLGLQFN---NSDQKGLVAQLTLIFFD--PLMPTDEPLTKSDRNRLESSLGRATTFDPLSDQGGLHCLDVFRRSLLRTGPKPVPRNWIKRRSNANRVADKRRQQLIHCVTELREAGIKLRKRKTDRFWDVKFKKGILRVPRLLIHDGTKSLFLNLIALEQCHIDCGNEITSFVIFMDNLINSPEDVAYLHYCGIIEHWLGSDADVADLFNQLCQEVVFDINDSYLSRLSEDVNHYYNHKWNTWRASLKHNYFSNPWAIVSLFAAVVLLLLTFAQTFYGVYA 527          

Query:   76 QMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPN-CDEYSSLSKASLKFF-NFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHK-HITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            ++ +   +NI +L +SM   L S+               CCI+ VP+ L  +N + Y P +VSIGP HHGKP+L  M++HK RYL+D L RT     +L DYL+++   E+ +R CY+ET + S  E ++M++VD  FIIE+  R      R      +D ++N               ENQ+PFF+LE LF+ ++ + P+  ++  S++K + +F  +   L+  +E  +K       HL+D +     H  P        +++  I S  +LHQAG+KFK G + +  DIKF+NG+LE+P++ +      LF N +AFEQC  HC K +I  Y + +N L  T  D   L    I+EN+L  DE ++  F  L K+    ++  Y   L +++N +C   W+   A     YF+ PWS +S  A +I L+LT IQ V +I
Sbjct:    3 EITNDTLVNIDELAASMRGELDSLPVLS---------SKCCIYTVPKRLHHLNEKAYTPQLVSIGPLHHGKPELRPMEEHKKRYLQDFLQRTK---LSLVDYLKVIEKNEKKLRDCYAETIEFSSDEFIKMILVDAAFIIEVLLRYHFKPMRKE--KENDRVYNKPWAIQDIRKDMWLLENQLPFFILEDLFDPARITLPSGKNQMLSITKLAYEFSKDLWDLEEMEEKSQKNKSPKVQHLVDFL--WICHQPPQSKSKKKLKTLG-IPSATELHQAGVKFKLGSSKNLFDIKFKNGILEIPRLEIVGATELLFRNLLAFEQC--HCSKNYINDYVIIINHLVNTAKDVELLVKDGIVENWLWDDEGMSALFHGLVKETFVIVDHFYFSGLVEELNAYCRKPWHKWQATLKQHYFNNPWSIISFIAAVILLVLTTIQAVCSI 425          

Query:  139 KSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDE-----DLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            +S+E+   + R      S CIF  P+   ++N   Y P +VS+GPYH GK  +   + HKW +L  LL+R+      L++YL  +   E  IR CYSET  +S  + V+MM++D  F++E+   +  L+  +  +D  D IF                ENQ+P+F+L ++ N S  +     E   L    L       L  +D+     DLE+Y                     HP       S   I+ V +L  +GIKF+  +  SFLDI FRN VLE+P +T++D    + +N VA E C     K+ T Y  FMNCL   P D +FLC   II  +   D+ V   F  LGK+ AF+I   YL ++F++V  +    ++  WA    TYF +PWSF+S  +  I L+LT +Q+++++
Sbjct:   17 RSLEEGRGIERQGGRSSSICIFPFPRSFDKINPNAYQPELVSLGPYHRGKDHVLEFEDHKWFFLGKLLSRSRTD---LSNYLGALKLNERSIRDCYSETISMSSHDFVEMMLLDSCFVLEL---LRNLNHSEDMIDEGDPIFTRPWLIPILIRDLLKFENQLPYFLLHLILNLSGGNGDIKLEPDPLPILHLLDLFHLSLLPTDQVIICIDLEEY---------------------HP-------SDQSIQGVTQLRPSGIKFRPRKCDSFLDINFRNCVLEIPSVTINDFTSTVLVNCVALEHCEEKRSKYFTDYVSFMNCLINQPRDVTFLCSEGIITRFSQDDQYVADLFNTLGKNVAFNIRECYLSKIFREVESY----YSSNWATMRRTYFSSPWSFISVLSASILLVLTMVQSIMSV 401          

Query:   73 IQMASPD--AINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSET-RKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPD--DAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQR--SDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKF--RNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            +QM S D  +++I +L  S+E  LK++               C I++VP+ L E+NG+ Y P ++SIGP H+GK +L  M++HK  YLR+ L  +      + D++  +A  E  +R CY+ET  KLSK E V+M+++D  F+I  F     L    P +     D IFN               ENQ+PFF++E LFN SK    +C+EYS + K S  F   A  Q   S+E LEK   L   H +D +R          P+  A  +     SV +LH+AGIKFK G + + L IKF    G LE+PQ+ + D    LF N  AFEQC    +K++  Y   ++ L     D   L    IIEN+L  ++ V+  F+NL K+   ++N  Y   + +D+N++ +   +   A     YF  PW+ +S  A  + ++LT IQTV +I
Sbjct:   15 MQMDSGDHVSLDIAKLAESVEGKLKTLRSFS---------DQCSIYRVPERLRELNGKAYTPRVISIGPLHYGKEELIEMEEHKRLYLREFLELSKVR---VRDFIAAIAESETRLRSCYAETFDKLSKEEFVEMVLLDCSFLIMFF-----LKAFSPVIQSRYIDRIFNKPWMLDEISIDLCLLENQLPFFIVEDLFNLSKLQH-HCEEYSMI-KISYAFL-LAAWQSWVSEEILEKINLLKVEHFVDFLRICQQPAQETQPKKLATITTP---SVAELHRAGIKFKLGSSINPLLIKFDDNKGTLEIPQLKIGDHAEILFRNLQAFEQCNYDANKYVCNYITMLSLLVPDAKDVEILVKEGIIENWLHDNDAVSRLFRNLSKENVINVNNFYFSGVVEDLNKYYSKRVHKWKAALKQKYFRNPWTIISVVAAAVIVILTIIQTVCSI 440          

Query:   73 IQMASPD--AINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETR-KLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKA----SLKFFNFAVLQRSDEDLEKYYHLGGV-HLLDLIRKTYIHDIPHPPRGNAFESVDKIR--SVKKLHQAGIKFKKGEAASFLDIKF--RNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            +   SPD  +++I +L  S+E  LKS+     L         C I++VP+ L E+N + Y P ++SIGPYHHGK +L+ M++ K  YLR+ L     +   + D++  +A +E  +R CY+ET   LSK E V+M+++D  F+I    +      ++  +D    IFN               ENQ+PFF++E LFN SK    +C+E+S +       S K++++       ED+ K++ L    H +      Y+     P +      +  +   SV +LHQAG+KFK G + + LDIKF    G LE+P   +DD    L  N  AFEQC+   + ++  Y   ++ L  +  D   L    I+EN L  +E V   F+NL K+    I+  Y   L +D+N++C    +   A     YFD PW+ +S  A  + L+LT  QTV +I
Sbjct:    9 VPKVSPDHVSLDIAKLAESVERKLKSLRSFSDL---------CFIYRVPKRLRELNEKAYTPQVISIGPYHHGKKELQEMEEQKRLYLREFLGLCKVS---VKDFITAIAERESRLRNCYAETTDNLSKEEFVEMVLLDCSFLIMFLLKAFSFDIQEANID---RIFNKLWMREEIQFDLCLLENQLPFFIVEDLFNLSKIQH-HCEEHSMIELTHDLLSDKWYSWV-----PEDISKHFKLSKAEHFVG-----YLAICQRPSQHMQPTKLTNLTAPSVAELHQAGMKFKLGSSINLLDIKFDDNKGTLEIPHKIIDDHTEILLRNLQAFEQCHCGVNIYVCDYITMLSFLVPSAKDVEILVKNGILENCLPDNEAVASLFRNLSKENTLAIDTFYYSGLVEDLNKYCGKRRHKWKATLKQKYFDNPWTIISLVAATVLLILTITQTVCSI 434          

Query:   52 GRDGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGV------HLLDLIRKTYIHDIPHPPRGNAFESVDKIR--SVKKLHQAGIKFKKGEAASFLDIKF--RNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            GR      +++   +++I +L  S+ E L+       +  P +   +CCI+KVP+ L E+N + Y P +VSIGP HHG   L+ M+ HK  YL++ +ART  +   +  +++L+  KE  +R CY+ET   S    ++M+++D  F+I +  +      R       D+IF                ENQ+PFF+LE L   S P   N  + ++L   +  FF++   +     + +Y  LGGV      HL+D +  T  H    P     +E ++ +   SVK+LHQAG+KF    +   LDIKF    G LE P++ +DD    +  N  AFEQC+   H ++  Y   M        D   L +  IIEN+L S+EEV   F NL K  +          L KD+N  C   WN   A     YF+TPW+ +S S  +I L+LT IQ+V +I
Sbjct:    4 GRPSSTNHELSHQVSLDIDRLAQSVTEELE-------ISNPFSD--TCCIYKVPERLRELNEKAYTPRLVSIGPIHHGNDKLKAMEDHKRMYLKEFIARTKVS---VKGFIELIKEKETRLRNCYAETNGFSSEYFIKMILMDAAFVIMLLLKWTYTDFRGS----RDSIFYPPYKSVDVRVDICLLENQLPFFILEELCGLS-PIFGNSPK-ATLIGLTHWFFSY---EWGSWAVGEY--LGGVDFSEVKHLVDFL--TIYH---RPTEQQQYEELEVLTAPSVKELHQAGVKFVLSSSKHLLDIKFDRNKGRLEFPRLQLDDRTEIIIRNMQAFEQCHGLTHGYVGDYIFLMGLFVSASKDVEMLVENRIIENWLPSNEEVVQLFYNLNKQNSVWSGTFLFKGLIKDLNAFCERPWNKWKANLKQNYFNTPWAAVSVSGAVILLILTVIQSVCSI 432          

Query:   46 NGGRDGDVVIQMASPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHP------PRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY------ASDGPGGH 1419
            NGGRD  + I      A N  Q T S+E+    +++T WLL P+AG  SCCIF++PQ+L+E+N + Y PHIVSIGPYH+G   L+MMQQHKWR+LRDLL RTP  GP L DY Q+VA  EEDIR CYSET  L   +LV++MV+DGLF IE+F +V RLS  DP    DD IFN               ENQIPF VL+ LF++SK SR   D  SSL++ +L+FF+FAV +R DE L+++  +   HLLDL+R ++I +  H       P+GN    V  I+S KKLH AGIKFK+ EA SFLDI+F NGVLE+P +T+DDLR  +FLNFVAFEQCY+HC KHITTYA  M+CL  TP D +FL D+NIIENYLG+DEEV HFFKNLGKD  FDI+ SYL +LFKDVNE+  N+W+V+WAGF   YFD PWSF+SA A ++ LLLTAIQT   +Y      AS+G G H
Sbjct:    3 NGGRDAVITIA-----ATNNIQTTISLEQG---IQETKWLLHPAAGNSSCCIFRLPQYLLEINKKAYQPHIVSIGPYHYGDTHLDMMQQHKWRFLRDLLVRTPSPGPNLDDYRQVVASMEEDIRRCYSETINLCGQDLVEVMVLDGLFTIELFCKVGRLSPSDP----DDPIFNLAWIFPNLIRDLLRLENQIPFIVLQTLFDKSKSSRE--DSNSSLAQLALEFFSFAV-ERPDEVLKQHVSVEAKHLLDLLRLSFIPEPHHRSPQNQNPKGNTSPLVQFIQSAKKLHLAGIKFKEREANSFLDIRFCNGVLEIPNITLDDLRTDIFLNFVAFEQCYSHCSKHITTYAALMSCLISTPVDAAFLSDKNIIENYLGTDEEVAHFFKNLGKDVPFDIDESYLCKLFKDVNEYHRNIWHVRWAGFRFKYFDNPWSFLSAVAAVVLLLLTAIQTFFTVYDYFNSLASNGGGRH 457          

Query:  160 WLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIR-----KTYIHDIPHPPRGNAFESVDKIR-SVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGPGG 1416
            WLL P AG  SCCIFKV Q L E+N +TY PHIVS GP+HHG   LEM+ QHKW+YLR LLARTP  GPTL  Y Q+VA  EE+IR CYSET  LS  +LV+MMV+DGLF IE+F +V +LS  DP    DD IFN               ENQIPFF+L+ LF++SKPSR + D  SSL+K +L FF +A+        + +  + G HLLDL+R     K Y H     PR N    V  I+ S KKL QAGIKFK  EA SFLDI+F NGVLE+P + +D+LR  L +NFVAFEQCY+HC KH+T+YA FM+CL  TP D SFLCD+ I+ENYLG+DEEV HFFKNLGK   FDI+ SYL +LFK+VNE+  N+W+V+W GF   YF TPWSF+SA A +I LLLTAIQT   +Y    P G
Sbjct:    1 WLLHPLAGKESCCIFKVRQCLAEINKKTYQPHIVSCGPFHHGDQHLEMIHQHKWKYLRGLLARTPSNGPTLDHYQQVVAAMEEEIRECYSETISLSSDDLVEMMVLDGLFTIELFCKVGKLSPSDP----DDPIFNLAWVFANILQDLFRFENQIPFFLLQKLFDESKPSRKDSD--SSLAKLALDFFRYALETPEQVLNQDFTTVEGKHLLDLLRWSFIPKPYDHSPQEEPR-NVRPLVQLIKYSAKKLRQAGIKFKTREAVSFLDIRFCNGVLEIPHVVIDNLRTDLLMNFVAFEQCYSHCSKHVTSYAAFMSCLIRTPEDVSFLCDKKIVENYLGTDEEVVHFFKNLGKGVTFDIDGSYLWKLFKEVNEYHINMWHVRWEGFRSKYFGTPWSFLSALAAVILLLLTAIQTFFTVYEYASPSG 418          

Query:  160 WLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGP 1410
            WLL PSAG  SCCIFKV Q LVE+N +TY PHIVS GPYH+G   LEM+QQHK R++RDLL    P GPTL  Y Q+V                         MV+DGLF +E+F +  +LS  DP    DD IFN               ENQIPFF+L+ LF++SKPSR + D  SSL+K +L FF +A   R+   L           + LI+                       S KKL QAGIKFK  EA SFL+I+F NGVLE+P + +D+LR  L +NFVAFEQCY+HC K +T+YA FM+CL  TP D  FLCD+NIIENYLG+DEEV HFF+NLGKD   DI   YL +LFKDVNE+  ++W+V+W GF   YF TPW+F+SA A +I LLLTAIQ   A+Y    P
Sbjct:    1 WLLHPSAGNESCCIFKVRQCLVEINNKTYQPHIVSCGPYHYGDQHLEMIQQHKRRFVRDLLV---PNGPTLNHYQQVV-------------------------MVLDGLFTVELFCKAGKLSPSDP----DDPIFNLAWVFANILQDLFRFENQIPFFLLQKLFDESKPSRKDSD--SSLAKLALDFFRYAEEPRNVRPL-----------VQLIKY----------------------SAKKLRQAGIKFKTREAVSFLEIRFCNGVLEIPHIVIDNLRADLLMNFVAFEQCYSHCSKDVTSYAAFMSCLIRTPEDVLFLCDKNIIENYLGTDEEVVHFFQNLGKDVPLDIGEGYLWKLFKDVNEYHRSMWHVRWEGFRFKYFGTPWTFLSALAAIILLLLTAIQAFFAVYGYARP 350          

Query:   73 IQMASPDAINITQLTSSMEESL-KSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYI---HDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            IQ  +   I I ++      S+ K + +   LL  +AG  SCCIF++PQ L+E+NG++Y+P I+SIGPYH G+P L+M+++HKWRYL  LL+RT   G TL DY + +   + + R CYSE+  LS  E ++MMV+DG FIIE+F +  RL +     +  D + +               ENQIP+ VLE+LF+ +       D   +LS  +L+FFN   +QR D  ++ + +L GVHLLDL+R + I   HD PH  RGN   +   I  V KL +AGIK +  E  SFL IKF+ GV+E+P +T+DD      LN VA+EQC+  C KHITTYA  ++CL  T  D  +LCDRNIIEN  G+D +V  F  NLGKD AFD++  YL +LF DV+ +  N W+VQWA F  TYFDTPWS +SA A LI L++T +QT   +
Sbjct:    6 IQQETNHVIRIWEVNEDRLASIHKKISEPPRLLSNAAGKPSCCIFRIPQSLLEINGKSYNPQILSIGPYHRGEPRLKMIEEHKWRYLGSLLSRTEAKGLTLNDYFKALEPLQAEARECYSESINLSTDEFIEMMVLDGCFIIELFRKFGRLVK----FEEYDPLVSMVWIISFLVRDLLRLENQIPYLVLEVLFDLTTLPEHK-DNGKTLSLLALEFFNHH-MQRPDHVIQNHQNLTGVHLLDLLRASVIPPGHDEPH--RGNIIPT-HTIHCVSKLRRAGIKLRPCEGESFLVIKFKRGVIEMPTITIDDFMSSFLLNCVAYEQCHKSCSKHITTYATLLDCLVNTYKDVEYLCDRNIIENCFGNDGDVARFVNNLGKDVAFDMDRCYLAKLFNDVHHYYGNSWHVQWASFKYTYFDTPWSCISAFAALILLIMTLLQTFYTV 440          

Query:  193 CCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSK----PSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHC-HKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            CCI++VP+ L  V+ + Y P +VSIGP HHGK  L+ M+ HK RYL+D + RT  +   LADY+Q V  +E  +R CY+ET ++S  E V++++VD  FIIE+  R       D   D +D IFN               ENQ+PFF+LE LF+  K     +  N +  S L+     F N   ++ +D ++EK       H +D  R  ++  +P  P            S+ +LH+AG+KF+ G   +  +IKF NG+L++P++ + D       N +AFEQC  HC   +I  Y V M+    T  D   L    I+EN LG   E +    NL      D N  Y   L  D+N++C   W+   A     Y +TPW+ +S +A +  L+LT IQTV ++ ++
Sbjct:   15 CCIYRVPERLRRVSEKAYTPQVVSIGPLHHGKEGLKAMEDHKKRYLQDYIRRTRVS---LADYVQKVKDQEAKLRSCYAETIQVSSDEFVRIILVDAAFIIEVLLRYRF----DELQDENDCIFNKPYMLQDVWPDMRLLENQLPFFILEELFDPDKIEVSSNNNNIERLSILNLCHNFFKNLMHIEGTDGNMEKLCASKVEHFVDFCRNLHL-PLPLKPHAKGRLETLNTPSITELHRAGVKFRVGSPKNLFNIKFANGILKIPKLAISDETELTIRNLLAFEQC--HCMENYINDYVVIMDRFVNTAKDVELLVKHGIVENSLGDSSEGSTLINNLADGVIVDPNDFYFAILCADLNKYCRTSWHKWQANLRQNYCNTPWATISIAAAIFLLILTFIQTVCSVISA 412          

Query:   85 SPDAINITQLTSSMEESLKSVEKTDWLLRPSAGMRSCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSE--TRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEK------------------YYHLGGVHLLDLIRKTYIHDIPHP-PR------GNAFESVDK-----IRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIY 1395
            SPD+  +  +   +E++ +      W           CI++VP +L E + +   P IVS+GPYHHG+  L  M +HKWR L  +L R       +  YL  +   EE  R CY       +S +E V+MMV+DG F++E+F R      +      +D IF                ENQ+P F+L+ L           ++   ++K +L+FF+   L  +DE L K                      GG+H LD+ R++ +     P PR       +A    DK     I  V +L +AGIKFKK +   F D+KF NG+L +P++ + D    LFLN +AFEQC+  C   IT+Y +FM+ L  +P D  +L    IIE++LGSD EV   F  L ++  FDIN SYL +L +DVN + N+ WN   A     YF+ PW+ +S  A ++ L LT  QT   +Y
Sbjct:   76 SPDSEWVINIKDKLEQAGQDDAAGTWA--------KLCIYRVPHYLREGDDKAIVPQIVSLGPYHHGRRRLRQMDRHKWRSLHHMLKRN---NQNIQLYLDSIKEVEEKARACYEGPVAMGISSNEFVEMMVLDGCFVLELF-RGAAEGFKQLGYPRNDPIFAMRGSMHSIQRDMIMLENQLPLFILDRLLGLQFGDP---EQKGLVAKLALRFFD--PLMPTDEPLTKSDRSKLESSLGYANTFDPLSDQGGLHCLDVFRRSLLRRGLQPTPRVWIKKWSHANRVADKRRQQLIHCVTELREAGIKFKKRKTDRFWDVKFENGILRIPRLLIHDGTKSLFLNLIAFEQCHLDCSNDITSYVIFMDNLINSPQDVGYLHYCGIIEHWLGSDAEVADLFNRLCQEVVFDINDSYLSRLSEDVNRYYNHRWNAWRASLKHNYFNNPWATLSFVAAVVLLFLTFAQTFYGVY 527          

Query:  169 RPSAGMRSCCIFKVPQWL--VEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPP--TGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDD-AIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGV-HLLDLIRKTYIHDIPH-PPRGNAF---------------------------------------ESVDKIRSVKKLHQAGIKFKKGEAA-SFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            R S      CI++VP  L  +    +T  P +VSIGPYH GK +L   + +K ++L  LL+R         L++Y + +   EE  R CYSE+  +S  + V+MMV+DG FIIE+F R+          D DD  I                 +NQ+PFFVLE LF  S     N     SL+  +L+FFN   L R  E L++   L G  HLLDL   +++  IPH PPR  +                                         S + I+   +L  +GIKF+  +AA SFLDI FRNGVL++P +T++DL + +F+N +AFE+C+ +  +  TTY  FM+CL  +  D + LC   II ++  +D+ V   F  LG+   F+I   YL   F+DV  +    ++  WA FM TYF  PWSF+S  +  I L+LT  QT +AI
Sbjct:   15 RRSGRKSPVCIYRVPPSLNGISPTPETIEPEMVSIGPYHRGKDELLEFESYKLQFLNLLLSRETNGRRHDLLSEYYKAMKKLEESTRSCYSESIPMSSPDFVEMMVLDGCFIIELFRRMS--------ADEDDHPILTRLWLIPILTRDLLKLQNQLPFFVLEKLFEIS-----NFRTEHSLTLLALEFFNHT-LPRPSEVLKRASKLRGAKHLLDLFHLSFLPPIPHEPPRKKSIFQRTSDVLSEATFKTLIWFCMLFISSTPHDDHDADQNYRPSSESIQCTTQLRPSGIKFRPLKAAESFLDINFRNGVLQIPPITINDLTIAVFINCMAFERCHQYTSQLFTTYIAFMSCLINSTRDVTLLCADGIITSFSQNDQNVAELFTKLGEKVVFNIRKCYLSTQFRDVEAY----YSSHWATFMRTYFSKPWSFISVFSAFILLVLTGAQTAMAI 451          

Query:  613 ENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYASDGP 1410
            ENQ PF +L+ LF++SK  R N D  SSLSK +L+FFN+A  QR D+ L++ +                 + P PP       ++ I+S KKL  AGIKFK  EA +F+DI+F NG+LE+P + +DDL   L +NFVAFEQCY H  KH TTYA FM+CL  TPAD SFLCD+NI+ENYLG+DEE                   YL +LFKDVNE+  ++W+V+W GF   YF TPW+F+SA A +I LLL AIQ   A+Y    P
Sbjct:    5 ENQFPFSLLQKLFDESKALRGNSDS-SSLSKLALQFFNYA-FQRPDQVLDQDFSAA--------------EKPRPP-------IELIQSAKKLRLAGIKFKTREAMTFIDIRFCNGLLEIPHIVLDDLCTDLLMNFVAFEQCYTHRSKHFTTYAAFMSCLIRTPADVSFLCDKNIVENYLGTDEE------------------GYLWKLFKDVNEYHRSMWHVRWEGFRFKYFGTPWTFLSALAAIILLLLNAIQAFFAVYVCARP 229          

Query:  193 CCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSK----PSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGGVHLLDLIRKTYIHDIPHPPRGNAFESVDKIRSVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHC-HKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAIYAS 1401
            CCI++VP+ L  V+ + Y P +VSIGP HHG+  L+ M+ HK RYL+D + R   T  +LADY+Q V  +E  +R CY+ET ++S  E V++++VD  FIIE+  R       D   D  D IFN               ENQ+PFF+LE LF+  K     +  N +  S L+     F     ++ +D ++EK       H +D  R   + D+           +    S+ +LH+AG+KFK G   +  DI+F NG+LE+P++ + D       N +AFEQC  HC   +I  Y V ++    T  D   +  + I+EN LG     +    NL      D N  Y   L  D+N++C   W+   A     Y +TPW+ +S +  +  L+LT IQ V ++ ++
Sbjct:   15 CCIYRVPERLRRVSEKAYTPQVVSIGPLHHGEEGLKAMEDHKKRYLQDYIRR---TRVSLADYVQKVKDQEAKLRSCYAETIQVSSDEFVRIILVDAAFIIEVLLRY----RFDELQDEIDRIFNKPWLLPDVWPDMRLFENQLPFFILEELFDPEKIKVSSNNNNIERLSMLNLCHNFFKTLMHIEGTDGNMEKLCTSKVEHFVDFCRN--LGDL----------KLLNTSSITELHRAGVKFKVGSPKNLFDIQFANGILEIPKLAISDETELTIRNLLAFEQC--HCMENYINNYVVIVDRFVNTATDVELVVKQGIVENMLGDSSGGSTLINNLADGVIVDSNDFYFAILCADLNKYCRTSWHKWQANLRQNYCNTPWATISIATAIFLLILTFIQAVCSVISA 401          

Query:  190 SCCIFKVPQWLVEVNGQTYHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYSETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNXXXXXXXXXXXXXXXENQIPFFVLEMLFNQSKPSRPNCDE---YSSLSKASLKFFNFAVLQRSDEDLEKYY-HLGGV----HLLDLIRKTYIH-DIPHPPRGNAFE----------SVDKIR---------SVKKLHQAGIKFKKGEAASFLDIKFRNGVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHKHITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 1392
            SCCI++VP+    VN   Y P +VSIGP HHGK  LE M++HK RYL++ L RT  +   L D ++ +  +E  +R CY+ET   S  E V++++VD  FI+E+  +    + R P +  +DAIF                ENQ+P F+LE LF   + + P+  +    + ++  SLKFF   +    D D E     L       H LDLI ++    ++   P G   E          +  +++         SV +L+QAG++FK G   +  DI+F NG+ E+P++ VDD       N +AFEQC+ + H HI  Y   M+       D   L +R IIEN LG  +E++  F NLG     D N ++   L +D+N + ++  +   A     YF+TPW  +S  A ++ L+LT IQTV +I
Sbjct:   36 SCCIYRVPERFRRVNENAYTPQVVSIGPLHHGKKGLEAMEEHKKRYLQEFLCRTKVS---LEDCIKKIRDREARLRSCYAETNGFSSDEFVRIILVDAAFIVELLLKH---NGRTP-IKENDAIFKKPKIILDLETDMQLLENQLPIFILEDLFYLQQGTLPSDSDDRLSTFVTDLSLKFFTSRMTLMRDADQESILDRLSSTKKVEHFLDLILRSLCQSEVELIPLGCQSEVELIPLGYVTTTTRVKTSVTPSLTPSVTELYQAGVEFKVGSMKNLFDIRFTNGICEIPKIRVDDDTEISLRNLLAFEQCH-YMHNHICDYMTIMDGFVNNAIDVDLLVERGIIENILGDRKELSALFNNLGLGICSDENFTF-ASLCEDLNRYYSSKRHKMMANLRHNYFNTPWRTLSVIAAVVLLILTLIQTVCSI 455