MDP0000784168, MDP0000784168 (mRNA) Malus spp. (apple)

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSG--DDH-----TVLSEEKAQL-SASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAA--DRLRQLATEEKP-NWSFSEDWVTI 1047
            M+W+RG  IG GSF+T+  A   + S     L+A K+ +   S  L+NEK VLDQ+G C  IIRCFG++ SVENG +  NL+LEYA+GG+LA  +K NGG L E DV+ +T+SVL+GL +IH KGF HCDLKLQN+L+F DG  KIADFGLAK  G+    V+VRGTPL MAPESVN+NEY+S  D+WALGC V EM +GKP W+     N+  LL+ I   DELP+IP+ELS +GKDF+SKCFVKDP++RWTA+MLL+H+FV+   DD      TV  + K ++ S+SPR PF+F +W+S+ SS  SP    WS + L+S  DWS   S   ++  DR++QL ++ +  NW+FS+ W+T+
Sbjct:    1 MDWVRGNSIGHGSFSTVNLAIPRNDSG--ASLMAVKSCDVFDSVFLENEKDVLDQLGDCEHIIRCFGSEESVENGHRLSNLLLEYAAGGSLAHWVKNNGGCLRESDVRHYTRSVLKGLSYIHAKGFAHCDLKLQNLLLFEDGELKIADFGLAKKVGQKLEGVQVRGTPLCMAPESVNENEYDSPCDIWALGCAVVEMITGKPAWNCRADANIAALLIKIGVSDELPEIPQELSNEGKDFLSKCFVKDPQRRWTADMLLDHSFVADHYDDEFNSTTTVTFKNKKEVPSSSPRCPFEFQEWISIPSS--SPNSEVWSHRELESRIDWSSLSSTPSSSPVDRIQQLTSDHQGCNWAFSDSWITV 357          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEK----AQLSASPRGPFDFPDWVS--VASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M W+RG+ +G GSFAT+  A  T+ S+      A K+S    S  LKNEK++LD++G+ P +I CFG DH+VENGE++YN+ LEYA+GG+LAD++K++GGRLPE  V+R T+S++ GL+ IH  G+VHCD+KLQN+LVF +G  KIADFGLAK  GE   K+E RGTPL+M+PESVNDNEYES +D+WALGC V EM +GKP WD   G N++ LL+ I  G+ELP+IPEELSE+GKDF+ KCFVKDP +RW+AEMLL H FV+G+  +     +       S SPR  FD   W S   AS   SP   EW          W    S  P  +RLR+L T + P NWS S+ W +I
Sbjct:    1 MNWVRGESLGSGSFATVNIAIPTNTSTQFLSSTAVKSSHVQTSSMLKNEKEILDRLGASPYVINCFGDDHTVENGEEYYNIFLEYAAGGSLADQVKKHGGRLPESYVRRCTRSLVEGLKHIHDNGYVHCDVKLQNILVFQNGDVKIADFGLAKEKGEKPGKLECRGTPLFMSPESVNDNEYESPADIWALGCAVVEMVTGKPAWDVR-GSNIWSLLIRIGAGEELPKIPEELSEEGKDFLLKCFVKDPMKRWSAEMLLNHPFVNGETVSFQKVNEPLPLPSPSPSPRTHFDLTHWASTLTASLPSSPDSDEWR--------MWEFGSSCSP-ENRLRRLVTVQTPANWSESDGWTSI 347          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD--DHTVLSEEKAQLSASPRGPFDFPDWVSVASSEI--SPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M W+RG+ +G GSFAT+  A  T+ S+      A K+S    S  LKNEK++LD +G+ P +I CFG DH+VENGE++YN+ LEYA+GG+LAD++K++GGRLPE  V+R T+S++ GL+ IH  G+VHCD+KLQN+LVF +G  KIADFGLAK  GE   K+E RGTPL+M+PESVNDNEYES +D+WALGC V EM +GKP WD   G N++ LL+ I  G+ELP+IPEELSE+GKDF+ KCFVKDP +RW+AEMLL H FV+G+      ++E     S SPR  FD   W S  ++ +  SP   EW          W    S  P  +RLR+L T + P NWS S+ W ++
Sbjct:    1 MNWVRGEPLGSGSFATVNIAIPTNTSTQFLSSTAVKSSYVHTSSMLKNEKEILDCLGASPYVINCFGDDHTVENGEEYYNIFLEYAAGGSLADQVKKHGGRLPESYVRRCTRSLVEGLKHIHDNGYVHCDVKLQNILVFQNGDVKIADFGLAKEKGEKQGKLECRGTPLFMSPESVNDNEYESPADIWALGCAVVEMLTGKPAWDVR-GSNIWSLLIRIGAGEELPKIPEELSEEGKDFLLKCFVKDPMKRWSAEMLLNHPFVNGETVSFQKVNEPLPLPSPSPRTHFDLTHWASTVTALLPSSPDSDEWR--------MWESGSSCSP-ENRLRRLVTVQTPANWSESDGWTSV 345          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD--DHTVLSEEKAQLSASPRGPFDFPDWVSVASSEI--SPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M W+RG  +G GSFAT+  A  T+ S H P   A K+S+   S  LKNEK++LD +G+ P +I+CFG DH+VENGE++YN+ LEYA+GG+LAD++KR+GGRLPE  V+R T+S++ GL+ IH  G+VHCD+KLQN+LVF +G  KIADFGLAK  GE     E RGTPL+M+PESVNDNEYES +D+WALGC V EM +GKP WD   G N++ LL+ I  G+ELP+IPEELSE+GKDF+ KCFVKDP +RW+AEMLL H FV+ +      ++E     S SPR  FD   W S  ++ +  SP   EW      +EF      S     +R R+L T++ P NWS S+ W ++
Sbjct:    1 MIWVRGDSLGTGSFATVNIAIPTNTSIHFPSPTAVKSSDVHSSSMLKNEKEILDCLGASPYVIKCFGHDHTVENGEEYYNIFLEYAAGGSLADQVKRHGGRLPESYVRRCTRSIVEGLKHIHDNGYVHCDVKLQNILVFENGDVKIADFGLAKEKGEKQGTFECRGTPLFMSPESVNDNEYESPADIWALGCAVVEMLTGKPAWDVR-GSNIWSLLIRIGVGEELPKIPEELSEEGKDFLLKCFVKDPMKRWSAEMLLHHPFVNNEAVSFHKVNEPLPLPSPSPRTHFDLTHWASTVTTWLPSSPDSDEWR----MAEFG-----SSCSPENRFRRLLTDQTPANWSESDGWTSV 345          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE-SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEI--SPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M+W+RG  +GRGSFAT+  A  T+  +  P L   K++++  S  L+NEK VLD++GSCP+IIRCFG D S ENG ++YNL LEYA+GG+LADEL+ + GR+PE   + +T+ ++ GL  +H  GFVHCD+KLQN+LVF DG  KIADFGLA+ AGE    K E RGTP++M+PE V   E ES +D+WALGC V EM +GKP W    G +M+ LL+ I  G E+P+IP  LSEDGKDF+ KCF+KDP++RW+AEMLL+H F+  DD         ++  SPR  FDFPDWVS  ++ +  SP+F E           W     F    DRLRQL T  +P +WS S+ W ++
Sbjct:    1 MDWVRGDAVGRGSFATVSLAIPTTNYNQFPSLTVVKSADAQTSCWLRNEKHVLDRLGSCPRIIRCFGDDCSFENGVEYYNLFLEYAAGGSLADELRNHDGRIPEPQAREYTRDIVEGLSHVHKNGFVHCDIKLQNILVFEDGRIKIADFGLAREAGERQGKKSECRGTPMFMSPEQVTGGECESPADIWALGCAVVEMVTGKPAWQVENGSSMWSLLLRIGVGQEVPEIPNNLSEDGKDFIEKCFIKDPKKRWSAEMLLKHPFLLNDDTVSFK----RVHESPRSHFDFPDWVSSVANSLPSSPEFQE----------KWGFDDEFCSPEDRLRQLLTVNRPASWSESDGWSSV 340          

Query:    1 MEWIRGKEIGRGSFATIYTAK-STSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGS-CPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGES---DNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIX-GDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD-DHTVLSEEK--------AQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEWIRG+ IG G+F+T+  A  S + S  LPPL+A K+++S  + SL+NEK VLD++G  C +I+RCFG D +VENGE+ +NL LEYAS G+L   LK+  G  LPE  V+RHT SVLRGL  IH  GF HCDLKL N+L F DGA KIADFGLAK  GE    +  V++RGTPLYMAPESVNDNEY S  DVWALGC V EM SGK  W    G N   LL+ I  GDELP IPEELSE GKDF+SKCFVKDP++RWTAEMLL H FV+ D D+  L EE+         ++S SPR PF+FPDWVSV+S            + +DS              +R+  L T+  P+WS +  WVT+
Sbjct:    1 MEWIRGETIGYGTFSTVSLATPSNNDSGELPPLMAVKSADSYGAASLENEKSVLDKLGDDCNEIVRCFGEDRTVENGEEMHNLFLEYASRGSLESYLKKLAGEGLPESTVRRHTGSVLRGLRHIHANGFAHCDLKLGNILWFGDGAVKIADFGLAKRIGEVTAINEGVQIRGTPLYMAPESVNDNEYGSEGDVWALGCAVVEMFSGKTAWSLKEGSNFMSLLIRIGVGDELPMIPEELSEQGKDFLSKCFVKDPKKRWTAEMLLHHPFVAVDLDYDGLVEEEDFVVKLKTEEVSTSPRCPFEFPDWVSVSSGS----------QMIDSP------------EERVTSLVTDLIPDWSVTNSWVTV 343          

Query:    1 MEWIRGKEIGRGSFATIYTA-KSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGS-CPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE---SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD-DHTVLSEEK--------AQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEWIRG+ IG G+F+T+  A +S + S   PPL+A K+++S  + SL NEK VLD +G  C +I+RCFG D +VENGE+ +NL LEYAS G+L   LK+  G  +PE  V+RHT SVLRGL  IH  GF HCDLKL N+L+F DGA KIADFGLAK  G+    +  V++RGTPLYMAPESVNDNEY S  DVWALGC+V EM SGK  W    G N   LL+ I  GDE+P IPEELSE G+DF+SKCFVKDP++RWTAEMLL H FV+ D DH VL +E+          +S SPR PF+FPDWVSV+S            + +DS              +R+  L T+  P+WS +  WVT+
Sbjct:    1 MEWIRGETIGYGTFSTVSLATRSNNDSGEFPPLMAVKSADSYGAASLANEKSVLDNLGDDCNEIVRCFGEDRTVENGEEMHNLFLEYASRGSLESYLKKLAGEGVPESTVRRHTGSVLRGLRHIHANGFAHCDLKLGNILLFGDGAVKIADFGLAKRIGDLTALNYGVQIRGTPLYMAPESVNDNEYGSEGDVWALGCVVVEMFSGKTAWSLKEGSNFMSLLLRIGVGDEVPMIPEELSEQGRDFLSKCFVKDPKKRWTAEMLLNHPFVTVDVDHDVLVKEEDFVVNMKTEDVSTSPRCPFEFPDWVSVSS----------GSQTIDS------------PDERVASLVTDMIPDWSVTNSWVTV 343          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSC-PQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEI--SPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M+W+RG  +GRGSFAT+  A  T+  +  P L A K++E+  S  L+NEK VLD++GS  P+IIRCFG D S ENG ++YNL LEYA+GG+LADELK + G++ E + + +T++++ GL  +H  GFVHCD+KLQN+LVF DG  KIADFGLA+ AG+   K E RGTP++M+PE     E ES +D+WALGC + EM +GKP W    G +M+ LL+ I  G+E+P+IP  LSEDGKDF+ KCF+KDP++RW+AEMLL+H F+  D          ++  SPR  FDFPDWVS  ++ +  SP+F +           W     F    DRLRQL T  +P +WS S+ W ++
Sbjct:    1 MDWVRGDALGRGSFATVSLAIPTTNPNQFPSLTAVKSAEAQTSCWLRNEKHVLDRLGSSSPRIIRCFGDDCSFENGVEYYNLFLEYAAGGSLADELKNHDGQISEHEAREYTRAIVEGLSHVHKSGFVHCDIKLQNILVFGDGGIKIADFGLAREAGQKQEKSECRGTPMFMSPEQATGGECESPADIWALGCTIVEMVTGKPAWQVEKGASMWSLLLRIGVGEEVPEIPNNLSEDGKDFIEKCFIKDPKKRWSAEMLLKHPFLINDGTVPFK----RVHESPRSHFDFPDWVSSVTNSLPSSPEFQD----------KWDFDDGFCSPEDRLRQLLTVNRPASWSESDGWSSV 340          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADG----AAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDEL-PQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            M W+RG  IGRGSFAT+  A S +     PPL+A K+     S +L+NE QVL ++G C +++RC+G ++S E G + YN++LEYA+GG+LAD + R+ G L E DV+R+T+S+LRGL++IH  GFVHCD+KLQN+L+ +       AKI DFGLAK A +   K   RGTP+YMAPE ++  E+ + +D+WALGC V EMASGKP W   PG +   LL  I G +  P+ P ELSE+GKDF+ KCF++DPR+RWTAEMLL+H FV+G D TV  ++  + S SPR PFDFP+W S  +   +P       ++L+S  + S   S+   ADR+RQL T++ PNWS SE W  +
Sbjct:    1 MTWVRGGTIGRGSFATVSLAVSRAGEDRFPPLMAVKSCGVEDSATLRNETQVLSRLGDCQEVLRCYGDEYSCEGGRELYNVLLEYAAGGSLADYV-RDFGALVESDVKRYTRSILRGLDYIHGVGFVHCDVKLQNLLLCSSNDSVFCAKIGDFGLAKKAEKVAEKKGFRGTPMYMAPECLSGEEHSAAADIWALGCAVVEMASGKPAWQCQPGTDANALLFRIWGGKASPETPSELSEEGKDFLEKCFLRDPRKRWTAEMLLDHPFVAGTDVTVPLKQSDEASTSPRSPFDFPEWASDHTPSPTPDSEACFDRDLNSWLN-SSSHSWTSPADRIRQLVTDQTPNWSVSESWFAV 352          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADG----AAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDEL-PQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            M W+RG  IGRGSFAT+  A S +     PPL+A K+     S +L+NE QVL ++G C +++RC+G ++S E G + YN++LEYA+GG+LAD + R+ G L E DV+R+T+S+LRGL++IH  GFVHCD+KLQN+L+ +       AKI DFGLAK A +   K   RGTP+YMAPE ++  E+ + +D+WALGC V EMASGKP W   PG +   LL  I G +  P+ P ELSE+GKDF+ KCF++DPR+RWTAEMLL+H FV+G D TV  ++  + S SPR PFDFP+W S  +   +P       ++L+S  + S   S+   ADR+RQL T++ PNWS SE W  +
Sbjct:    1 MTWVRGGTIGRGSFATVSLAVSRAGEDRFPPLMAVKSCGVEDSATLRNETQVLSRLGDCQEVLRCYGDEYSCEGGRELYNVLLEYAAGGSLADYV-RDFGALVESDVKRYTRSILRGLDYIHGVGFVHCDVKLQNLLLCSSNDSVFCAKIGDFGLAKKAEKVAEKKGFRGTPMYMAPECLSGEEHSAAADIWALGCAVVEMASGKPAWQCQPGTDANALLFRIWGGKASPETPSELSEEGKDFLEKCFLRDPRKRWTAEMLLDHPFVAGTDVTVPLKQSDEASTSPRSPFDFPEWASDHTPSPTPDSEACFDRDLNSWLN-SSSHSWTSPADRIRQLVTDQTPNWSVSESWFAV 352          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADG----AAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDEL-PQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            M W+RG  IGRGSFAT+  A S +     PPL+A K+     S +L+NE QVL ++G C +++RC+G ++S E G + YN++LEYA+GG+LAD + R+ G L E DV+R+T+S+LRGL++IH  GFVHCD+KLQN+L+ +       AKI DFGLAK A +   K   RGTP+YMAPE ++  E+ + +D+WALGC V EMASGKP W   PG +   LL  I G +  P+ P ELSE+GKDF+ KCF++DPR+RWTAEMLL+H FV+G D TV  ++  + S SPR PFDFP+W S  +   +P       ++L+S  + S   S+   ADR+RQL T++ PNWS SE W  +
Sbjct:    1 MTWVRGGTIGRGSFATVSLAVSRAGEDRFPPLMAVKSCGVEDSATLRNETQVLSRLGDCQEVLRCYGDEYSCEGGRELYNVLLEYAAGGSLADYV-RDFGALVESDVKRYTRSILRGLDYIHGVGFVHCDVKLQNLLLCSSNDSVFCAKIGDFGLAKKAEKVAEKKGFRGTPMYMAPECLSGEEHSAAADIWALGCAVVEMASGKPAWQCQPGTDANALLFRIWGGKASPETPSELSEEGKDFLEKCFLRDPRKRWTAEMLLDHPFVAGTDVTVPLKQSDEASTSPRSPFDFPEWASDHTPSPTPDSEACFDRDLNSWLN-SSSHSWTSPADRIRQLVTDQTPNWSVSESWFAV 352          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXA-GESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEK-PNWSFSEDWVTI 1047
            M+W RG  +G GS AT+  A S         + A K+ E   S+SL+ E+++L  + S P I+   G D + EN +  YNL +EY  GGTL D ++R GG+L E  +  + + +++GL++IH +G VHCD+K QNVL+  DG AKIADFG AK   G+ D KV + GTP +MAPE     +    SDVWALGC + EMA+G   W  N    +  L      +ELP IP  LS+  KDF+SKC  +DP++RWTA  LL+H FV G+ +    + +   S SP    D   W S+  SE      + S  N                A+R+R+L T  +  NW+  ++WVTI
Sbjct:    1 MDWTRGHTLGSGSSATVSLANSLRSGD----VFAVKSVELSRSESLQREERILSSLRS-PYIVGYKGCDITRENKKLMYNLFIEYMPGGTLGDAIRRGGGQLHESMIGIYARQIVQGLDYIHSRGLVHCDIKGQNVLIGEDG-AKIADFGCAKWTNGKDDRKVPIAGTPFFMAPEVARGEDQGYPSDVWALGCTIIEMATGGAPWP-NVANAVAALYRIGFSEELPWIPSFLSDQAKDFLSKCLRRDPKERWTASQLLKHPFV-GELNPQAKQVQESYSDSPTSILDQNFWSSLEESEAQGYLKQASFSN--------------SPAERIRKLWTFSRVENWTRDDNWVTI 329          

Query:   10 IRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVF--ADGA--AKIADFGLAKXAGESD--NKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSE 816
            ++G  +GRG    +Y+A S +   H P  +A K++ S +S  L  EK++L ++  CP+I+ C+G D ++E G + YNL LEYA GG+L+D ++ +GG LPE +VQ +T+ +L+GL  IH KG+VHCD+K  N+L+F   DG    KIADFGLAK  GE       +  GTP YM+PESV   E E   DVW+LG  V EM +GK VW     +    LL  I   E P+IPE +SE+GKDF+  CF ++ ++RWTA MLL H F + +  ++  E
Sbjct:    7 VKGNLLGRGRHGRVYSAFSFN---HTPHHLAVKSAFSSHSSLLAKEKRILSELQHCPEIVHCYGDDSTMEEGVETYNLFLEYAPGGSLSDLIRNSGGTLPESNVQLYTRMILKGLCHIHEKGYVHCDIKPSNMLIFPLEDGGNKVKIADFGLAKRIGEERALQLPQFSGTPAYMSPESVLYGEDEPPLDVWSLGITVVEMLTGKLVWRR---LGKEDLLFSIVFGE-PEIPESVSEEGKDFLRMCFRREAKERWTARMLLNHPFTTEEPSSMAME 274          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSV-ENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNK-------VEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVS 789
            EW++GK +G GSF T++ A S +        V   A E     SL+NE  +L+++ S P I+RC G D  V   GE   NL +EY +GG+L++   + GG L E  ++ +T+ +L+GLE++H    VHCDLK QNVL+ + G  K+ADFG AK   +  +K         + GTPL+MAPE + +      SD+W+LGC + EMA+G+P W       M  ++M    +++PQIP  LS++G DF++KC  ++P +RWTAE LL H FVS
Sbjct:   14 EWVKGKMVGSGSFGTVHLAMSKATGGLF---VVKSAQEGPGLKSLENEATMLEKLHS-PYIVRCMGRDSFVGRQGEGRLNLFMEYMAGGSLSNVADKFGGILEEKVIRLYTREILQGLEYLHKNEIVHCDLKCQNVLLGSSGNVKLADFGCAKRLRDLKSKGASMTSWQSISGTPLWMAPEVLRNEGVTLASDIWSLGCTIIEMATGRPPWSGEVSNPMAAVMMIACSNKIPQIPTHLSKEGLDFLAKCLDRNPAKRWTAEELLSHPFVS 279          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLP-PLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEE-KAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEK----PNWSFSEDWVTI 1047
            M+W RG  +GRGS AT+  A     +SHL   + A K++E   S  LK E+++L  + S   +I   G + + ENG++ YNL +EYA+GGTL     +  G L E  ++ +T+++L+GL+++H    VHCD+K +N+L+  DG  KI D G A+ A +  + V   GTP +MAPE     E    +DVWALGC + EMA+G+  W            +   GD +P+IP  +SED KDF+ KC V+DP QRW+   LL H FV  ++  V S+E     S+SP    D   W S +  E+ P                  +KS+    +R+  LA        PNW + E+WVT+
Sbjct:    1 MDWTRGCTLGRGSSATVSIA-----TSHLSGDIFAVKSTELSQSKLLKREQRILSTVRSA-HVIEYRGWNVTCENGKQMYNLCMEYAAGGTL-----KQRGSLGEAAIRANTRAILQGLQYLHSNCIVHCDIKSENILITGDGL-KIGDLGCARLADDFSDSV--CGTPAFMAPEVARGEEQGFAADVWALGCTIIEMATGRAPWTDVSDPVSAVYRIGFSGD-VPEIPGWVSEDAKDFLGKCLVRDPVQRWSVGELLGHPFV--NEACVFSKEVYGSSSSSPTSVLDQRFW-SSSIEELYP----------------FHKKSWNSPRERIHFLANSNSNSGLPNWGWDENWVTV 321          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLP-PLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEE-KAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEK----PNWSFSEDWVTI 1047
            M+W RG  +GRGS AT+  A     +SHL   + A K++E   S  LK E+++L  + S   +I   G + + ENG++ YNL +EYA+GGTL     +  G L E  ++ +T+++L+GL+++H    VHCD+K +N+L+  +G  KI D G A+ A +  + V   GTP +MAPE     E    +DVWALGC + EMA+G+  W            +   GD +P+IP  +SE+ KDF+ KC V+DP +RW+   LL H FV  ++  V S+E     S+SP    D   W S +  E+ P                  +KS+    +R++ LA        PNW + E+WVT+
Sbjct:  444 MDWTRGCTLGRGSSATVSIA-----TSHLSGDIFAVKSTELSQSKLLKREQRILSTVRSA-HVIEYRGWNVTCENGKQMYNLCMEYAAGGTL-----KQRGSLGEAAIRANTRAILQGLQYLHSNCIVHCDIKSENILITGEGL-KIGDLGCARLADDFSDSV--CGTPAFMAPEVARGEEQGFAADVWALGCTIIEMATGRAPWTDVSDPVSAVYRIGFSGD-VPEIPGWVSEEAKDFLGKCLVRDPVKRWSVGELLGHPFV--NEACVFSKEVYGSSSSSPTSVLDQRFW-SSSIEELYP----------------FHKKSWNSPRERIQFLANSNSNSGLPNWGWDENWVTV 764          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDS-----LKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESV-NDNEYESCSDVWALGCLVAEMASGKPVWDHNPGV-NMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            +W +G+ +GRG+F  +Y   + S +  +  +   K     ++       L  E  +L Q+ S P I++ +G+    E GE+  ++ LEY SGG++  +L +  G   E  +Q + + ++ GL ++H +  VH D+K  N+LV  +G  K+ADFG+AK    S + +  +G+P +MAPE V N N Y    D+W+LGC + EMA+ KP W    GV  +FK+       ++P+IP+ LS D K FV  C  +DP  R TA  LL+H+FV
Sbjct:  194 KWKKGRLLGRGTFGHVYVGFN-SENGQMCAIKEVKVVSDDHTSKECLKQLNQEINLLSQL-SHPNIVQYYGS----EMGEETLSVYLEYVSGGSI-HKLLQEYGPFKEPVIQNYARQIISGLAYLHGRSTVHRDIKGANILVGPNGEIKLADFGMAKHINSSSSMLSFKGSPYWMAPEVVMNTNGYSLAVDIWSLGCTILEMATSKPPWSQYEGVAAIFKI---GNSRDVPEIPDHLSNDAKSFVRLCLQRDPSARPTALQLLDHSFV 451          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGS--------C-PQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESV-NDNEYESCSDVWALGCLVAEMASGKPVWDHNPGV-NMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            W +GK +GRG+F  +Y   ++         +      + +SD  K+ K+   Q+G         C P I++ +G++     G+K Y + LEY SGG++  +L +  G+L E  ++ +T+ +L GL ++H K  VH D+K  N+LV   G  K+ADFG+AK        +  +G+P +MAPE + N N      D+W+LGC V EMA+ KP W    GV  MFK+       +LP IP+ LS++GKDFV +C  ++P  R TA  LLEH FV
Sbjct:  410 WKKGKLLGRGTFGHVYVGFNSESGE-----MCAMKEVTLFSDDAKS-KESAKQLGQEIVLLSRLCHPNIVQYYGSETV---GDKLY-IYLEYVSGGSIY-KLLQEYGQLGELAIRSYTQQILSGLAYLHAKNTVHRDIKGANILVDPSGRVKLADFGMAKHITGQSCPLSFKGSPYWMAPEVIRNSNGCNLAVDIWSLGCTVLEMATTKPPWSQFEGVAAMFKI---GNSKDLPAIPDHLSDEGKDFVRQCLQRNPLHRPTAAQLLEHPFV 666          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSSHLP----PLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESV-NDNEYESCSDVWALGCLVAEMASGKPVWDHNPGV-NMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            W +G+ +GRG+F  +Y   ++            L +  A     +  L  E  +L ++   P I++ +G++ +V+  +K Y + LEY SGG++  +L +  G+L E  ++ +T+ +L GL ++H K  VH D+K  N+LV  +G  K+ADFG+AK        + ++G+P +MAPE + N N      D+W+LGC V EMA+ KP W    GV  MFK+       ELP IP+ LSE+GKDFV +C  ++P  R TA  LLEH FV
Sbjct:  413 WKKGRLLGRGTFGHVYLGFNSESGEMCAMKEVTLFSDDAKSKESAQQLGQEISLLSRLRH-PNIVQYYGSE-TVD--DKLY-IYLEYVSGGSIY-KLLQEYGQLGEIAIRSYTQQILSGLAYLHAKNTVHRDIKGANILVDPNGRVKLADFGMAKHITGQSCPLSLKGSPYWMAPEVIKNSNGCNLAVDLWSLGCTVLEMATTKPPWSQYEGVAAMFKI---GNSKELPTIPDHLSEEGKDFVRQCLQRNPLHRPTAAWLLEHPFV 669          

Query:    7 WIRGKEIGRGSFATIYTAKSTSP----------------SSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGAD--HSVENGEKFYNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADG---AAKIADFGLAKXAGESDNKVE-------VRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD 795
            W R   +G+GSF  +  A S +P                S  +    A K++E   S SL+ E ++L  +   P +++  G +   S  +   +YN+++E+  GG+LA  +K+ G   L E+ V+   + ++ GL  +H +G+VHCD+K  N+L+  DG    AKIADFGLAK      N  E       VRGT  YMAPE+V+    +  +D+WALGC V EM +GKP+                              DGKDF+ +C V+  R RW+AEML+ H F+S D
Sbjct:   40 WTRKHNLGKGSFGFVSFATSRAPIIVCHDDDDGGGGGGGSDSVLTNFAVKSAEVSMSSSLRRETKILWDLKLSPHVVQSHGDEMTQSRFDNRTYYNILMEFCEGGSLAKWIKKLGNPGLSEYHVRLFARDMVLGLVHVHSRGYVHCDIKPSNILLARDGDGYTAKIADFGLAKRVAAHPNGEEDDDELGAVRGTYRYMAPETVSHRVQDQYADIWALGCTVLEMMTGKPL------------------------------DGKDFLERCLVRSLRSRWSAEMLIHHPFLSLD 301          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLP----PLVAXKASES---GYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE---SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD 795
            + W +G+ IG G+F  +Y   +      L      + A  AS+     +   L+ E ++L  + S P I+R  G     E+     N++LE+  GG+++  L + G   PE  ++ +TK +L GLE++H  G +H D+K  N+LV   G  K+ADFG +K   E         ++GTP +MAPE +    +   +D+W++GC V EMA+GKP W       +  L         P IPE L+ + KDF+ KC  K+P  R  A  LL+H FVSG+
Sbjct:   65 IRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVSIAANSASKEKTQAHIRELEEEVKLLKNL-SHPNIVRYLGTAREDES----LNILLEFVPGGSISSLLGKFGS-FPESVIRMYTKQLLLGLEYLHKNGIMHRDIKGANILVDNKGCIKLADFGASKKVVELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPWSQQ-YQEVAALFHIGTTKSHPPIPEHLTAEAKDFLLKCLQKEPNLRPAASELLQHPFVSGE 332          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLP-------PLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGES---DNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDEL-PQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSG 792
            + W +G+ IG G+F  +Y   +      L        P  A K    G+   L+ E Q+L  + S P I+R  G     ++     N+++E+  GG+++  L++ G   PE  +  +TK +L GLE++H  G +H D+K  N+LV   G  ++ADFG +K   E    +    ++GTP +MAPE +    +   +D+W++GC V EMA+GKP W        F  ++ I   +  P IPE+LS + KDF+ KC  K+P  R +A  LL+H FV+G
Sbjct:   66 IRWRKGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNL-SHPNIVRYLGTVRESDS----LNILMEFVPGGSISSLLEKFGS-FPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPWSEQ--YQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVTG 332          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPL-------VAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE---SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI----XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEE 819
            + W +G+ IGRG+F T+Y   +      L           A K     +   L+ E ++L  + S P I+R  G     E      N++LE+  GG+++  L++ G   PE  V+ +T  +L GLE++H    +H D+K  N+LV   G  K+ADFG +K   E         ++GTP +MAPE +    +   +D+W++GC V EM +GK  W        +K +  I         P IP+ +S D  DF+ KC  ++P  R TA  LL+H FV+G      S++
Sbjct:   66 IRWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNL-SHPNIVRYLGTVREDET----LNILLEFVPGGSISSLLEKFGA-FPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWS-----QQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLKHPFVTGKQKESASKD 341          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSD---SLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNE---YESCSDVWALGCLVAEMASGK-PVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            W +G+ +GRGSF ++Y   S          V+     S   +    L+ E ++L Q+     I+R  G   + ++G   Y + LE  + G+L    +R   +L +  V  +T+ +L GL+++H KGF+H D+K  N+LV A+GA K+ADFGLAK +  +D K   +GTP +MAPE +N  +   Y S +D+W+LGC V EM +G+ P  D  P   +F+    I    LP++P+ LS D + F+ KC   +P +R TA  LL H FV
Sbjct:  333 WQKGQLLGRGSFGSVYEGISGDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQH-QNIVRYRG---TAKDGSNLY-IFLELVTQGSLLKLYQRY--QLRDSVVSLYTRQILDGLKYLHDKGFIHRDIKCANILVDANGAVKLADFGLAKVSKFNDIK-SCKGTPFWMAPEVINRKDSDGYGSPADIWSLGCTVLEMCTGQIPYSDLEPVQALFR----IGRGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELLNHPFV 587          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPL-------VAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE---SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSG 792
            + W +G+ IGRG+F T+Y   +      L           A K     +   L+ E ++L  + S P I+R  G     +      N++LE+  GG+++  L++ G   PE  V+ +T+ +L GLE++H    +H D+K  N+LV   G  K+ADFG +K   E         ++GTP +MAPE +    +   +D+W++GC V EM +GK  W       +  +         P IP+ LS D KDF+ KC  + P  R TA  LL+H FV G
Sbjct:   67 ISWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNL-SHPNIVRYLGTVREDDT----LNILLEFVPGGSISSLLEKFGP-FPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQ-YKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLKHPFVMG 333          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSS-------HLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE--SDNKVEVRGTPLYMAPESVNDNE-YESCSDVWALGCLVAEMASGKPVWDHNPGV-NMFKLLMXIXGDELPQIPEE----LSEDGKDFVSKCFVKDPRQRWTAEMLLEHAF 783
            W++G+ IG+GSF  +Y   + +           +P   +   +     ++L++E   L  +     I++  G     EN    Y+L LEY +GG++   L R  GR  E  ++  T  VL+GL ++H KG +H D+K  N+L+  DG  KI+DFG+++ + +  S++ + +RGT  +MAPE V+  + Y +  D+W+LGC+V EM +GK  W +   V  MFK+         P IPE+    +S+ G++F+  CF  +P +R TA  LL H F
Sbjct: 1175 WMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHL-NIVQYLG----FENKNNIYSLFLEYVAGGSVGS-LIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKI---GKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPF 1439          

Query:   25 IGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYS-DSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLA-KXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEM-ASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEK 822
            IG+G+FAT++   +T     +      K+  S     S+  E  +L ++     I+R  G     E  E +  + LEY   G+L+  L  N G  PE  +  + ++VL+GL ++H +G +H D+K  N+L+   G AK++DFG A +   ESD +  V GTP +MAPE +  + +   SD+W+LGC + E+  S  P +D NP   M++    I  D+ P +P+++S +  +F+ +CF K   +R TA+ LL H +++ +   +++ ++
Sbjct:   83 IGKGAFATVFKGLNTLSGDFVAIKRFEKSKISNEQHSSVSTEFDILQRLNH-ENIVRILGR----EENENYIYIFLEYMENGSLSTILN-NFGTFPESLICNYVENVLKGLVYLHQEGVIHRDIKAANILINKAGEAKLSDFGTAGEIIKESDKRYSVVGTPYWMAPEVIEISGHCQVSDIWSLGCTIIELFTSYPPYFDLNPLGAMYR----ICQDDRPPLPDDISSELANFLERCFCKSTEERATAKELLSHPWITKNRTNLINHQR 341          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIG-----SCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFG----LAKXAGESDNKVE-VRGTPLYMAPESVNDNEYES---CSDVWALGCLVAEMASGKPVW---DHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            +W RG +IG G +  +YT  S         L+A K      +D  K  K+  D++        P ++R FG +    + E+ Y + +EY   GTL +E+ R G  L E  ++ ++K +   +  +H  G VH D+K  N+ + + G  K+ DFG    L   A     +V    GT  YMAPE +   + E     +D+W+LGC+V EM +GK  W   +HN     F+++  +     P IPE LS +GKDF+S C   DP+ RWTA  LL+H+FV
Sbjct: 1342 KWQRGNKIGEGQYGKVYTCISVDTGE----LMAMKEIRFQPNDH-KTIKETADELKIFEGIKHPNLVRYFGVEL---HREEMY-IFMEYCDEGTL-EEVSRLG--LQEHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHN-----FQIMYKVGMGHKPPIPERLSPEGKDFLSHCLESDPKMRWTASQLLDHSFV 1601          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVEN-----GEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKX-AGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTV 807
            ++W +G+ +GRG + ++Y   +         L A K  E    +S    K ++       +++R    D+ V        + F ++ LEY  GG+++  L + G    E  ++ +TK +L+GL F+H    +H D+K  N+L+   G  K++DFG +K  +G       ++GTP +MAPE +    +   SD+W+LGC++ EMA+ +P W +   +    +      + +P IP  +S++  DF++ CF +DP++R  A  LL+H F+   D  +
Sbjct:  168 IKWQKGQILGRGGYGSVYLGLNKDTGE----LFAVKQLEIVDINSDPKLKNMILSFSKEIEVMRSLRHDNIVRYLGTSLDQSFLSVFLEYIPGGSISSLLGKFGA-FSENVIKVYTKQILQGLSFLHANSIIHRDIKGANILIDTKGIVKLSDFGCSKSFSGIVSQFKSMQGTPYWMAPEVIKQTGHGRSSDIWSLGCVIVEMATAQPPWSNITELAAV-MYHIASSNSIPNIPSHMSQEAFDFLNLCFKRDPKERPDANQLLKHPFIMNLDDNI 436          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIG-----SCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFG----LAKXAGESDNKVE-VRGTPLYMAPESVNDNEYES---CSDVWALGCLVAEMASGKPVW---DHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            +W RG +IG G +  +YT  S         L+A K      +D  K  K+  D++        P ++R FG +    + E+ Y + +EY   GTL +E+ R G  L E  ++ +TK +   +  +H  G VH D+K  N+ + + G  K+ DFG    L   A     +V    GT  YMAPE +   + E     +D+W+LGC+V EM +GK  W   +HN     F+++  +     P IPE LS +GK F+S C   DP+ RWTA  LL+HAFV
Sbjct: 1331 KWQRGNKIGEGQYGKVYTCISVDTGE----LMAMKEIRFQPNDH-KTIKETADELKIFEGIKHPNLVRYFGVEL---HREEMY-IFMEYCDEGTL-EEVSRLG--LQEHVIRLYTKQITVAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHN-----FQIMYKVGMGHKPPIPERLSPEGKAFLSHCLESDPKIRWTASQLLDHAFV 1590          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASE-----SGYSDSLKNEKQVLDQIGSCPQIIRCFGADH-------SVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAG---ESDNKVEVRGTPLYMAPESV-NDNE-YESCSDVWALGCLVAEMASGKPVWDHNPGVN-MFKLLMXIXGDE--LPQIPEEL----SEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDD 798
            +W++G+ IG G++  ++ A + +       L+A K  E     +G  D L+  K ++D I +  +I      DH         E  E   ++ LEY SGG++   L RN G   E  V+  ++ VL GL ++H KG +H DLK  N+L+  DG  KI+DFG++K +    ++D  + ++G+  +MAPE + ND++ Y +  DVW+LGC+V EM +G+  W  +  +  MFKL     G E   P IP EL    S +   F++ CF  +   R TAE LL H F+  D+
Sbjct:  824 KWMKGELIGNGTYGKVFLAMNINTGE----LIAVKQVEIPQTINGRHDQLR--KDIVDSINA--EISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCL-RNYGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKL-----GTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHPFMKCDE 1098          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSG--DDH-----TVLSEEKAQL-SASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAA--DRLRQLATEEKP-NWSFSEDWVTI 1047
            M+W+RG  IG GSF+T+  A   + S     L+A K+ +   S  L+NEK VLDQ+G C  IIRCFG++ SVENG +  NL+LEYA+GG+LA  +K NGG L E DV+ +T+SVL+GL +IH KGF HCDLKLQN+L+F DG  KIADFGLAK  G+    V+VRGTPL MAPESVN+NEY+S  D+WALGC V EM +GKP W+     N+  LL+ I   DELP+IP+ELS +GKDF+SKCFVKDP++RWTA+MLL+H+FV+   DD      TV  + K ++ S+SPR PF+F +W+S+ SS  SP    WS + L+S  DWS   S   ++  DR++QL ++ +  NW+FS+ W+T+
Sbjct:    1 MDWVRGNSIGHGSFSTVNLAIPRNDSG--ASLMAVKSCDVFDSVFLENEKDVLDQLGDCEHIIRCFGSEESVENGHRLSNLLLEYAAGGSLAHWVKNNGGCLRESDVRHYTRSVLKGLSYIHAKGFAHCDLKLQNLLLFEDGELKIADFGLAKKVGQKLEGVQVRGTPLCMAPESVNENEYDSPCDIWALGCAVVEMITGKPAWNCRADANIAALLIKIGVSDELPEIPQELSNEGKDFLSKCFVKDPQRRWTADMLLDHSFVADHYDDEFNSTTTVTFKNKKEVPSSSPRCPFEFQEWISIPSS--SPNSEVWSHRELESRIDWSSLSSTPSSSPVDRIQQLTSDHQGCNWAFSDSWITV 357          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEK----AQLSASPRGPFDFPDWVS--VASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M W+RG+ +G GSFAT+  A  T+ S+      A K+S    S  LKNEK++LD++G+ P +I CFG DH+VENGE++YN+ LEYA+GG+LAD++K++GGRLPE  V+R T+S++ GL+ IH  G+VHCD+KLQN+LVF +G  KIADFGLAK  GE   K+E RGTPL+M+PESVNDNEYES +D+WALGC V EM +GKP WD   G N++ LL+ I  G+ELP+IPEELSE+GKDF+ KCFVKDP +RW+AEMLL H FV+G+  +     +       S SPR  FD   W S   AS   SP   EW          W    S  P  +RLR+L T + P NWS S+ W +I
Sbjct:    1 MNWVRGESLGSGSFATVNIAIPTNTSTQFLSSTAVKSSHVQTSSMLKNEKEILDRLGASPYVINCFGDDHTVENGEEYYNIFLEYAAGGSLADQVKKHGGRLPESYVRRCTRSLVEGLKHIHDNGYVHCDVKLQNILVFQNGDVKIADFGLAKEKGEKPGKLECRGTPLFMSPESVNDNEYESPADIWALGCAVVEMVTGKPAWDVR-GSNIWSLLIRIGAGEELPKIPEELSEEGKDFLLKCFVKDPMKRWSAEMLLNHPFVNGETVSFQKVNEPLPLPSPSPSPRTHFDLTHWASTLTASLPSSPDSDEWR--------MWEFGSSCSP-ENRLRRLVTVQTPANWSESDGWTSI 347          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD--DHTVLSEEKAQLSASPRGPFDFPDWVSVASSEI--SPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M W+RG+ +G GSFAT+  A  T+ S+      A K+S    S  LKNEK++LD +G+ P +I CFG DH+VENGE++YN+ LEYA+GG+LAD++K++GGRLPE  V+R T+S++ GL+ IH  G+VHCD+KLQN+LVF +G  KIADFGLAK  GE   K+E RGTPL+M+PESVNDNEYES +D+WALGC V EM +GKP WD   G N++ LL+ I  G+ELP+IPEELSE+GKDF+ KCFVKDP +RW+AEMLL H FV+G+      ++E     S SPR  FD   W S  ++ +  SP   EW          W    S  P  +RLR+L T + P NWS S+ W ++
Sbjct:    1 MNWVRGEPLGSGSFATVNIAIPTNTSTQFLSSTAVKSSYVHTSSMLKNEKEILDCLGASPYVINCFGDDHTVENGEEYYNIFLEYAAGGSLADQVKKHGGRLPESYVRRCTRSLVEGLKHIHDNGYVHCDVKLQNILVFQNGDVKIADFGLAKEKGEKQGKLECRGTPLFMSPESVNDNEYESPADIWALGCAVVEMLTGKPAWDVR-GSNIWSLLIRIGAGEELPKIPEELSEEGKDFLLKCFVKDPMKRWSAEMLLNHPFVNGETVSFQKVNEPLPLPSPSPRTHFDLTHWASTVTALLPSSPDSDEWR--------MWESGSSCSP-ENRLRRLVTVQTPANWSESDGWTSV 345          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD--DHTVLSEEKAQLSASPRGPFDFPDWVSVASSEI--SPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M W+RG  +G GSFAT+  A  T+ S H P   A K+S+   S  LKNEK++LD +G+ P +I+CFG DH+VENGE++YN+ LEYA+GG+LAD++KR+GGRLPE  V+R T+S++ GL+ IH  G+VHCD+KLQN+LVF +G  KIADFGLAK  GE     E RGTPL+M+PESVNDNEYES +D+WALGC V EM +GKP WD   G N++ LL+ I  G+ELP+IPEELSE+GKDF+ KCFVKDP +RW+AEMLL H FV+ +      ++E     S SPR  FD   W S  ++ +  SP   EW      +EF      S     +R R+L T++ P NWS S+ W ++
Sbjct:    1 MIWVRGDSLGTGSFATVNIAIPTNTSIHFPSPTAVKSSDVHSSSMLKNEKEILDCLGASPYVIKCFGHDHTVENGEEYYNIFLEYAAGGSLADQVKRHGGRLPESYVRRCTRSIVEGLKHIHDNGYVHCDVKLQNILVFENGDVKIADFGLAKEKGEKQGTFECRGTPLFMSPESVNDNEYESPADIWALGCAVVEMLTGKPAWDVR-GSNIWSLLIRIGVGEELPKIPEELSEEGKDFLLKCFVKDPMKRWSAEMLLHHPFVNNEAVSFHKVNEPLPLPSPSPRTHFDLTHWASTVTTWLPSSPDSDEWR----MAEFG-----SSCSPENRFRRLLTDQTPANWSESDGWTSV 345          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE-SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEI--SPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKP-NWSFSEDWVTI 1047
            M+W+RG  +GRGSFAT+  A  T+  +  P L   K++++  S  L+NEK VLD++GSCP+IIRCFG D S ENG ++YNL LEYA+GG+LADEL+ + GR+PE   + +T+ ++ GL  +H  GFVHCD+KLQN+LVF DG  KIADFGLA+ AGE    K E RGTP++M+PE V   E ES +D+WALGC V EM +GKP W    G +M+ LL+ I  G E+P+IP  LSEDGKDF+ KCF+KDP++RW+AEMLL+H F+  DD         ++  SPR  FDFPDWVS  ++ +  SP+F E           W     F    DRLRQL T  +P +WS S+ W ++
Sbjct:    1 MDWVRGDAVGRGSFATVSLAIPTTNYNQFPSLTVVKSADAQTSCWLRNEKHVLDRLGSCPRIIRCFGDDCSFENGVEYYNLFLEYAAGGSLADELRNHDGRIPEPQAREYTRDIVEGLSHVHKNGFVHCDIKLQNILVFEDGRIKIADFGLAREAGERQGKKSECRGTPMFMSPEQVTGGECESPADIWALGCAVVEMVTGKPAWQVENGSSMWSLLLRIGVGQEVPEIPNNLSEDGKDFIEKCFIKDPKKRWSAEMLLKHPFLLNDDTVSFK----RVHESPRSHFDFPDWVSSVANSLPSSPEFQE----------KWGFDDEFCSPEDRLRQLLTVNRPASWSESDGWSSV 340          

Query:    1 MEWIRGKEIGRGSFATIYTAK-STSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGS-CPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGES---DNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIX-GDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD-DHTVLSEEK--------AQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEWIRG+ IG G+F+T+  A  S + S  LPPL+A K+++S  + SL+NEK VLD++G  C +I+RCFG D +VENGE+ +NL LEYAS G+L   LK+  G  LPE  V+RHT SVLRGL  IH  GF HCDLKL N+L F DGA KIADFGLAK  GE    +  V++RGTPLYMAPESVNDNEY S  DVWALGC V EM SGK  W    G N   LL+ I  GDELP IPEELSE GKDF+SKCFVKDP++RWTAEMLL H FV+ D D+  L EE+         ++S SPR PF+FPDWVSV+S            + +DS              +R+  L T+  P+WS +  WVT+
Sbjct:    1 MEWIRGETIGYGTFSTVSLATPSNNDSGELPPLMAVKSADSYGAASLENEKSVLDKLGDDCNEIVRCFGEDRTVENGEEMHNLFLEYASRGSLESYLKKLAGEGLPESTVRRHTGSVLRGLRHIHANGFAHCDLKLGNILWFGDGAVKIADFGLAKRIGEVTAINEGVQIRGTPLYMAPESVNDNEYGSEGDVWALGCAVVEMFSGKTAWSLKEGSNFMSLLIRIGVGDELPMIPEELSEQGKDFLSKCFVKDPKKRWTAEMLLHHPFVAVDLDYDGLVEEEDFVVKLKTEEVSTSPRCPFEFPDWVSVSSGS----------QMIDSP------------EERVTSLVTDLIPDWSVTNSWVTV 343          

Query:    1 MEWIRGKEIGRGSFATIYTA-KSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGS-CPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE---SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD-DHTVLSEEK--------AQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEWIRG+ IG G+F+T+  A +S + S   PPL+A K+++S  + SL NEK VLD +G  C +I+RCFG D +VENGE+ +NL LEYAS G+L   LK+  G  +PE  V+RHT SVLRGL  IH  GF HCDLKL N+L+F DGA KIADFGLAK  G+    +  V++RGTPLYMAPESVNDNEY S  DVWALGC+V EM SGK  W    G N   LL+ I  GDE+P IPEELSE G+DF+SKCFVKDP++RWTAEMLL H FV+ D DH VL +E+          +S SPR PF+FPDWVSV+S            + +DS              +R+  L T+  P+WS +  WVT+
Sbjct:    1 MEWIRGETIGYGTFSTVSLATRSNNDSGEFPPLMAVKSADSYGAASLANEKSVLDNLGDDCNEIVRCFGEDRTVENGEEMHNLFLEYASRGSLESYLKKLAGEGVPESTVRRHTGSVLRGLRHIHANGFAHCDLKLGNILLFGDGAVKIADFGLAKRIGDLTALNYGVQIRGTPLYMAPESVNDNEYGSEGDVWALGCVVVEMFSGKTAWSLKEGSNFMSLLLRIGVGDEVPMIPEELSEQGRDFLSKCFVKDPKKRWTAEMLLNHPFVTVDVDHDVLVKEEDFVVNMKTEDVSTSPRCPFEFPDWVSVSS----------GSQTIDS------------PDERVASLVTDMIPDWSVTNSWVTV 343          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADG----AAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDEL-PQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            M W+RG  IGRGSFAT+  A S +     PPL+A K+     S +L+NE QVL ++G C +++RC+G ++S E G + YN++LEYA+GG+LAD + R+ G L E DV+R+T+S+LRGL++IH  GFVHCD+KLQN+L+ +       AKI DFGLAK A +   K   RGTP+YMAPE ++  E+ + +D+WALGC V EMASGKP W   PG +   LL  I G +  P+ P ELSE+GKDF+ KCF++DPR+RWTAEMLL+H FV+G D TV  ++  + S SPR PFDFP+W S  +   +P       ++L+S  + S   S+   ADR+RQL T++ PNWS SE W  +
Sbjct:    1 MTWVRGGTIGRGSFATVSLAVSRAGEDRFPPLMAVKSCGVEDSATLRNETQVLSRLGDCQEVLRCYGDEYSCEGGRELYNVLLEYAAGGSLADYV-RDFGALVESDVKRYTRSILRGLDYIHGVGFVHCDVKLQNLLLCSSNDSVFCAKIGDFGLAKKAEKVAEKKGFRGTPMYMAPECLSGEEHSAAADIWALGCAVVEMASGKPAWQCQPGTDANALLFRIWGGKASPETPSELSEEGKDFLEKCFLRDPRKRWTAEMLLDHPFVAGTDVTVPLKQSDEASTSPRSPFDFPEWASDHTPSPTPDSEACFDRDLNSWLN-SSSHSWTSPADRIRQLVTDQTPNWSVSESWFAV 352          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVEN-GEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVS--GDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEW+RG+ IG GS + ++ A   +   H P ++A K+     S  L+NE++V+ ++G CPQII+ FG  H+VE   E+ YNL+LEYA GG+L+ +L + G    E DV+ + +S+L+GL  IH KGFVHCDLKL N+L+F +   KIADFGLA+ AG++  + E+RGTPLYMAPESVNDN YES  D+WALGC V EM +GKP W   PG NMF LL+ I  GDELP IPEELS+ GKDF+SKCFVKDP++RWTA+MLLEH FV+  G     L EE    S SPR  FDFPDWVS+ S     +F+   G  L   F      S++ A+DR+RQLA+++  NWS S  WV +
Sbjct:    1 MEWVRGQCIGSGSSSRVHLA---TLKQH-PSVLAVKSCAESDSSLLENEREVVTELGYCPQIIQYFGDSHTVEEKNERLYNLLLEYAKGGSLSQKLNKFGC-FQERDVKDYARSILKGLRHIHAKGFVHCDLKLDNILLFENEEVKIADFGLARKAGKAQGRAEIRGTPLYMAPESVNDNVYESGVDIWALGCAVIEMLTGKPAWSCKPGTNMFVLLIRIGKGDELPTIPEELSQQGKDFLSKCFVKDPKRRWTADMLLEHPFVADQGKGTVPLREEIEVSSTSPRCHFDFPDWVSIQSPSPRSEFLSDDGVGL--VFPSLNSSSWISASDRIRQLASDQCCNWSDSGFWVAV 346          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFG-ADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD--DHTVLSEEKAQLSASPRGPFDFPDWVSVASS 888
            MEW+RG  +G GS +T++ A S + SS  P ++A K+     +  L+NE++VL++IG CPQII+CFG    + EN E  YNL+LEYA GG+L+ +LK++GG L E DV+ +T+S+L+GL ++H KGFVHCDLKL N+L+F +G  KIADFGLAK  G+   + E+RGTPLYMAPESVN NEYES +D+WALGC + EM +GKP W+  PG NMF LL+ I  GDELP IPEELS+ GKDF+SK FVKDP QRWTA+MLL+H FV+ +  ++  L EE  +LS SPR  F+FP+W S  SS
Sbjct:    1 MEWVRGGCLGYGSSSTVHLATSKNSSSTYPEVMAVKSCNQSDTTLLENEREVLNEIGFCPQIIQCFGDCQATEENNEFLYNLLLEYAKGGSLSYKLKKSGGCLQEGDVKDYTRSILKGLSYVHGKGFVHCDLKLDNILLFENGEVKIADFGLAKKTGQKQGRAEIRGTPLYMAPESVNKNEYESGADIWALGCAIVEMVTGKPAWNCKPGTNMFVLLIRIGEGDELPIIPEELSQQGKDFLSKIFVKDPTQRWTADMLLKHPFVADNFQENVPLKEESKELSTSPRCHFNFPEWASSQSS 300          

Query:    1 MEWIRGKEIGRGSFATIYTA-KSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGS-CPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGE---SDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD-DHTVLSEEK--------AQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEWIRG+ IG G+F+T+  A +S + S   PPL+A K+++S  + SL NEK VLD +G  C +I+RCFG D +VENGE+ +NL LEYAS G+L   LK+  G  +PE  V+RHT SVLRGL  IH  GF HCDLKL N+L+F DGA KIADFGLAK  G+    +  V++RGTPLYMAPESVNDNEY S  DVWALGC+V EM SGK  W    G N   LL+ I  GDE+P IPEELSE G+DF+SKCFVKDP++RWTAEMLL H FV+ D DH VL +E+          +S SPR PF+FPDWVSV+S            + +DS              +R+  L T+  P+WS +  WVT+
Sbjct:    1 MEWIRGETIGYGTFSTVSLATRSNNDSGEFPPLMAVKSADSYGAASLANEKSVLDNLGDDCNEIVRCFGEDRTVENGEEMHNLFLEYASRGSLESYLKKLAGEGVPESTVRRHTGSVLRGLRHIHANGFAHCDLKLGNILLFGDGAVKIADFGLAKRIGDLTALNYGVQIRGTPLYMAPESVNDNEYGSEGDVWALGCVVVEMFSGKTAWSLKEGSNFMSLLLRIGVGDEVPMIPEELSEQGRDFLSKCFVKDPKKRWTAEMLLNHPFVTVDVDHDVLVKEEDFVVNMKTEDVSTSPRCPFEFPDWVSVSS----------GSQTIDS------------PDERVASLVTDMIPDWSVTNSWVTV 343          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSH-LPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGV--NMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASS-EISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEWIR + IG GSF+T+  A ++  SS   P L+A K+S    S +L+NE+ VLD +G C +I+RCFG   +VENGE+ YNL LEYASGG+LAD +K +G  LPEF+V+R T+S+++GL  IH  GF HCD+KL+NVLVF DG  KI+DFGLAK     +  VE+RGTPLYMAPESVN  E+ES +D+WALGC V EM+SGK  W    GV  N+  LL+ I  GDE+P+IP ELSE+GKDFVSKCFVK+  +RWTAEMLL+H F++ DD +   EE    S SPR PFDFP W SV S    S  F    G                   +R+  L +E+ P+WS S DWV +
Sbjct:    1 MEWIRRETIGHGSFSTVSLATTSGSSSKAFPSLMAVKSSGVVCSAALRNERDVLDDLGDCSEIVRCFGEGRTVENGEEIYNLFLEYASGGSLADRIKSSGEALPEFEVRRFTRSIVKGLCHIHGNGFTHCDIKLENVLVFGDGDVKISDFGLAKRR-SGEVCVEIRGTPLYMAPESVNHGEFESPADIWALGCSVVEMSSGKTAWCLEDGVMNNVMSLLVRIGSGDEVPRIPVELSEEGKDFVSKCFVKNAAERWTAEMLLDHPFLAVDDES--GEEDEACSVSPRNPFDFPGWNSVQSPVNDSVMFGSLVGS----------------PEERISGLVSEKVPDWSVSCDWVNV 335          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGES----DNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVS---GDDH----TVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEW+RG+ IG G+F+T+ TA  +  S   P L+A K++++  + SL NEK VLD +G CP+IIRC+G D +VENGE+ +NL+LEYAS G+LA  +K+ GG  LPE  V+RHT SVLRGL  IH KGF HCD+KL N+L+F DG+ KIADFGLA             VE+RGTPLYMAPE VNDNEY S +DVWALGC V EM SGK  W    G +   LL+ I  GDELP+IPE LSE+GKDF+SKCFVKDP +RWTAEMLL H+FV+    DDH     V  +++ ++  SP+ PF+F DW S                     F      SF    +RL  L +   P+WS    W+T+
Sbjct:    1 MEWVRGETIGFGTFSTVSTATKSRNSGDFPALIAVKSTDAYGAASLSNEKSVLDSLGDCPEIIRCYGEDSTVENGEEMHNLLLEYASRGSLASYMKKLGGEGLPESTVRRHTGSVLRGLRHIHAKGFAHCDIKLANILLFNDGSVKIADFGLAMRVDGDLTALRKSVEIRGTPLYMAPECVNDNEYGSAADVWALGCAVVEMFSGKTAWSVKEGSHFMSLLIRIGVGDELPKIPEMLSEEGKDFLSKCFVKDPAKRWTAEMLLNHSFVTIDLEDDHRENFVVKVKDEDKVLMSPKCPFEFDDWDS---------------------FTLDSNPSFDSPVERLGSLVSGSIPDWSVGGSWLTV 341          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXG--DELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFD--FPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEE---KPNWSFSEDWVTI 1047
            WIRG  IGRGS AT+    + S         A K++E   S  L+ E+ +L ++ S P I++  G++ + EN +  YNL++EY SGG+L D +K +GG+LPE  ++ +T+ +L+GL ++H +G VHCD+K QNV++  +  AKI D G AK   E++N +E  GTP +M+PE     E    +DVWALGC V EMA+G   W   P +N     +   G   E P IP  LSE G+DF+ KC  KDP+QRWT E LL+H F+  +D+          S+SP    D  F D    + S    +  E    N  + F W          DR+++LA +E   +P+W  +  W+ +
Sbjct:    6 WIRGPIIGRGSTATVSLGITNSGD-----FFAVKSAEFSSSAFLQREQSILSKLSS-PYIVKYIGSNVTKENDKLMYNLLMEYVSGGSLHDLIKNSGGKLPEPLIRSYTRQILKGLMYLHDQGIVHCDVKSQNVMIGGE-IAKIVDLGCAKTVEENEN-LEFSGTPAFMSPEVARGEEQSFPADVWALGCTVIEMATGSSPW---PELNDVVAAIYKIGFTGESPVIPVWLSEKGQDFLRKCLRKDPKQRWTVEELLQHPFLDEEDNDSDQTGNCLNSSSPSTVLDQRFWDLCETSRSRFIKEDHEDPFAN-STNFLWDDDSL---PGDRIKKLAGDESSGEPDWE-TNGWIEV 343          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXG--DELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVT 1044
            + W RG  IGRGS AT+  A S+S       L A K+++   S  L+ E+ +L  + S P +++  G   + E+    YN+++EY SGG L D +K +GG+LPE +++ +T+ +L GL ++H +G VHCDLK  NVLV  +G  KIAD G AK    S +K E  GTP +MAPE     E    +DVWALGC + EM +G   W   P +N     M   G   E P IP  +S+  KDF+  C  +D +QRWT E LL+H F+  D+ +  S+     ++SP    D   W S  SS+     V    ++  +E+     +S    ADR+ +LA +E   +S   DW T
Sbjct:    3 INWTRGPIIGRGSTATVSIAISSSGE-----LFAVKSADLSSSSLLQKEQSILSTLSS-PHMVKYIGTGLTRESNGLVYNILMEYVSGGNLHDLIKNSGGKLPEPEIRSYTRQILNGLVYLHERGIVHCDLKSHNVLVEENGVLKIADMGCAK----SVDKSEFSGTPAFMAPEVARGEEQRFPADVWALGCTMIEMMTGSSPW---PELNDVVAAMYKIGFSGESPAIPAWISDKAKDFLKNCLKEDQKQRWTVEELLKHPFLDDDEESQTSDCLKNKTSSPSTVLDQRFWDSCESSK--SHLVSIDHEDPFAEYS----ESLDSPADRIEKLAGDE---FSSLLDWDT 330          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVE-NGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDH-NPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSE 891
            MEW RG+ +GRGS AT+Y A   +       ++A K+SE   S+ L+ E ++L  + S P +I   G++   E NG   YNL++EYA  GTL D   ++GGR+ E  V ++T+ +L+GLE+IH KG VHCD+K  NV++   G AKIADFG AK   +   +  V GTP +MAPE     +    SD+WA+GC + EM +G P W   +   +   +L  +    E P++P  L+E+ KDF+ KC  ++  +RWTA  LL H F++             +S SP    D   W SV   E
Sbjct:    1 MEWTRGRILGRGSTATVYAAAGHNSDE----ILAVKSSEVHRSEFLQREAKILSSLSS-PYVIGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVKYTRDILKGLEYIHSKGIVHCDVKGSNVVISEKGEAKIADFGCAKRV-DPVFESPVMGTPAFMAPEVARGEKQGKESDIWAVGCTMIEMVTGSPPWTKADSREDPVSVLYRVGYSSETPELPCLLAEEAKDFLEKCLKREANERWTATQLLNHPFLTTKPDIEPVLVPGLISNSPTSVTDQTFWRSVEEEE 294          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVE----NGEKF-YNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHX-KGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXG-DELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEW 915
            M W RGK +GRGS AT+  A        L    A K++E   S+ L+ E ++L  + S P +I   G + + E    NGE   Y+L++EYA  GTL D   +NGG + E  V ++T+ +L GLE+IH  KG  HCD+K  NVLV  +G AKIADFG AK   E +    VRGTP +MAPE+         SD+WA+GC V EM +G   W      +   +L  +    ELP++P  L+E  KDF+ KC  K+  +RWTA  LL H F+   +  +++     ++ SP    D   W SV   E+S     W
Sbjct:    1 MNWTRGKTLGRGSTATVSAATCHESGETL----AVKSAEFHRSEFLQREAKILSSLNS-PYVIGYRGCEITREPFHNNGEATTYSLLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQILLGLEYIHNSKGIAHCDIKGSNVLVGENGEAKIADFGCAKWV-EPEITEPVRGTPAFMAPEAARGERQGKESDIWAVGCTVIEMVTGSQPWIGADFTDPVSVLYRVGYLGELPELPCSLTEQAKDFLGKCLKKEATERWTASQLLNHPFLVNKEPELVT---GLVTNSPTSVTDQMFWRSV-EEEVSEDRSSW 302          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASE-----SGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAA-KIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVW-DHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            WIRG  +GRG F T+  A S         L A K+ +        ++SL+NE  +L  + S P I+R  G D S E    F NL LEY+  G +A     NGG + E  ++R+   ++  L  +H  G VHCD+K +NVLVF  G++ K+ADFG A    +S   V  RG+PL+MAPE V        SDVW+LGC V EM +GKP W DH      F  L  I   ++LP IP  LSE G+DF+ KC  +D  QRW+ + LL+H F+  D H     E     +SPR      DWV+    E             + E D    +S V A  R+ +LA     NW  S  W  +
Sbjct:   17 WIRGSCVGRGCFGTVSKALSKIDGG----LFAVKSIDLATCLPSQAESLENEIVILRSMKSHPNIVRFLGDDVSKEGTASFRNLHLEYSPEGDVA-----NGGIVNETLLRRYVWCLVSALSHVHSNGIVHCDVKSKNVLVFNGGSSVKLADFGSAVEFEKSTIHVSPRGSPLWMAPEVVRREYQGPESDVWSLGCTVIEMLTGKPAWEDHG-----FDSLSRIGFSNDLPFIPVGLSELGRDFLEKCLKRDRSQRWSCDQLLQHPFLCQDHHDSFFTE-----SSPRCVL---DWVNSEFDE-------------EEESDEWRPESMVSAMARISKLAITGGANWE-SNGWTEV 335          

Query:    7 WIRGKEIGRGSFATIYTAKS-TSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLP-EFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADR-LRQLATEEKPNWSFSEDWVTI 1047
            W+RG  IGRG F  + TA S T+        V    S    S+SL+NE  V   +   P I++  G   S E    F NL LEY   G +A    R GG++  E  +QR+T  ++  L  +H +GFVHCD+K +N+LV      K+ADFG A         +  RG+PL+MAPE +        SDVW+LGC + EM +GKP W+ + G++   L      DELP  P +LSE G+DF+ KC  +DP QRW+ + LL+H F+S   ++  +E      +SPR      DWV+             SG +L+ E +   R  F  AA   +  LAT     W  S+ WV +
Sbjct:    9 WVRGACIGRGCFGAVSTAISKTNGEVFAVKSVDLATSLPTQSESLENEISVFRSLKPHPYIVKFLGDGVSKEGTTTFRNLYLEYLPNGDVASH--RAGGKIEDETLLQRYTACLVSALRHVHSQGFVHCDVKARNILVSQSSMVKLADFGSAFRIHTPRALITPRGSPLWMAPEVIRREYQGPESDVWSLGCTIIEMFTGKPAWEDH-GID--SLSRISFSDELPVFPSKLSEIGRDFLEKCLKRDPNQRWSCDQLLQHPFLSQCHNSSPTE------SSPRCVL---DWVN-------------SGFDLEEEEEEVGRSEFEDAAKAIICNLATTGGVIWE-SDGWVEV 330          

Query:    7 WIRGKEIGRGSFATIYTAKS-TSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLP-EFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADR-LRQLATEEKPNWSFSEDWVTI 1047
            W+RG  IGRG F  + TA S T+        V    S    S+SL+NE  V   +   P I++  G   S E    F NL LEY   G +A    R GG++  E  +QR+T  ++  L  +H +GFVHCD+K +N+LV      K+ADFG A         +  RG+PL+MAPE +        SDVW+LGC + EM +GKP W+ + G++   L      DELP  P +LSE G+DF+ KC  +DP QRW+ + LL+H F+S   ++  +E      +SPR      DWV+             SG +L+ E +   R  F  AA   +  LAT     W  S+ WV +
Sbjct:   23 WVRGACIGRGCFGAVSTAISKTNGEVFAVKSVDLATSLPTQSESLENEISVFRSLKPHPYIVKFLGDGVSKEGTTTFRNLYLEYLPNGDVASH--RAGGKIEDETLLQRYTACLVSALRHVHSQGFVHCDVKARNILVSQSSMVKLADFGSAFRIHTPRALITPRGSPLWMAPEVIRREYQGPESDVWSLGCTIIEMFTGKPAWEDH-GID--SLSRISFSDELPVFPSKLSEIGRDFLEKCLKRDPNQRWSCDQLLQHPFLSQCHNSSPTE------SSPRCVL---DWVN-------------SGFDLEEEEEEVGRSEFEDAAKAIICNLATTGGVIWE-SDGWVEV 344          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVE-NGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD-DHTVLSEEKAQ--LSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTI 1047
            MEW+RG  +G GS +T++ A +   SS  P ++A K+     +  LKNE+++ ++IG CP+II+CFG   +VE + E+ YNL+LEYA GG+LA +LK++GG L E DV+ +T+S+L+GL  IH KGFVHCD+KL N+L+F +G  KIADFGLAK AGE   +VE+RGTPLYMAPESVN+NEYES  D+WALGC + EM +GK  W+  PG NMF LL+ I  GDELP IP+ELS++GKDF+SKCFVKDP QRWTA+MLLEH FV+     TV  +E+++  L  SPR  FDF +WVS+ S  +SP    WS   L+S F           +DR+RQL  +   NW  S  W+TI
Sbjct:    1 MEWVRGGCLGYGSSSTVHLATTKKSSSSYPAVMAVKSCNQSDTTLLKNEREIFNEIGFCPEIIQCFGDCQTVEEDNERLYNLLLEYAKGGSLAYQLKKSGGCLQESDVKDYTRSILKGLRHIHSKGFVHCDMKLDNMLLFENGEVKIADFGLAKKAGEKQERVEIRGTPLYMAPESVNNNEYESGVDIWALGCSIVEMVTGKSAWNSKPGANMFVLLIRIGEGDELPIIPKELSQEGKDFLSKCFVKDPTQRWTADMLLEHPFVADQVKETVPFKEESEELLPTSPRCHFDFSEWVSIQS--LSPISEVWSDGKLESIFPSLHSSCLASPSDRIRQLTGDRSCNWCDSGCWITI 352          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFG-ADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD--DHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLATEE 1008
            MEW+RG  +G GS +T++ A S + SS  P ++A K+     +  L+NE++VL++IG CPQII+CFG    + EN E  YNL+LEYA GG+L+ +LK++GG L E DV+ +T+S+L+GL ++H KGFVHCDLKL N+L+F +G  KIADFGLAK  G+   + E+RGTPLYMAPESVN NEYES +D+WALGC + EM +GKP W+  PG NMF LL+ I  GDELP IPEELS+ GKDF+SK FVKDP QRWTA+MLL+H FV+ +  ++  L EE  +LS SPR  F+FP+W S  SS  SP+   WS   ++S         +   ADR+R+LA ++
Sbjct:    1 MEWVRGGCLGYGSSSTVHLATSKNSSSTYPEVMAVKSCNQSDTTLLENEREVLNEIGFCPQIIQCFGDCQATEENNEFLYNLLLEYAKGGSLSYKLKKSGGCLQEGDVKDYTRSILKGLSYVHGKGFVHCDLKLDNILLFENGEVKIADFGLAKKTGQKQGRAEIRGTPLYMAPESVNKNEYESGADIWALGCAIVEMVTGKPAWNCKPGTNMFVLLIRIGEGDELPIIPEELSQQGKDFLSKIFVKDPTQRWTADMLLKHPFVADNFQENVPLKEESKELSTSPRCHFNFPEWASSQSSS-SPRSELWSDGKVESTSSSLNSSCWTSPADRIRELAGDQ 339          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVEN-GEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVS--GDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLA 999
            MEW+RG+ IG GS + ++ A   +   H P ++A K+     S  L+NE++V+ ++G CPQII+ FG  H+VE   E+ YNL+LEYA GG+L+ +L + G    E DV+ + +S+L+GL  IH KGFVHCDLKL N+L+F +   KIADFGLA+ AG++  + E+RGTPLYMAPESVNDN YES  D+WALGC V EM +GKP W   PG NMF LL+ I  GDELP IPEELS+ GKDF+SKCFVKDP++RWTA+MLLEH FV+  G     L EE    S SPR  FDFPDWVS+ S     +F+   G  L   F      S++ A+DR+RQLA
Sbjct:    1 MEWVRGQCIGSGSSSRVHLA---TLKQH-PSVLAVKSCAESDSSLLENEREVVTELGYCPQIIQYFGDSHTVEEKNERLYNLLLEYAKGGSLSQKLNKFGC-FQERDVKDYARSILKGLRHIHAKGFVHCDLKLDNILLFENEEVKIADFGLARKAGKAQGRAEIRGTPLYMAPESVNDNVYESGVDIWALGCAVIEMLTGKPAWSCKPGTNMFVLLIRIGKGDELPTIPEELSQQGKDFLSKCFVKDPKRRWTADMLLEHPFVADQGKGTVPLREEIEVSSTSPRCHFDFPDWVSIQSPSPRSEFLSDDGVGL--VFPSLNSSSWISASDRIRQLA 330          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSS---HLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADH-SVENGEKFYNLVLEYASGGTLADELKRNGG-RLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGA------AKIADFGLAKXAGESDNKVEV----RGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDD 798
            W RG  IG+G F ++Y A   +P S   + PP++A K++E   S SL+ EK+V + +  CP II+CFG +  S ++GE FYN++LEYASGG LA  +K++ G  LPE DV+R+T+S+L G+ +IH +G+VHCDLK +N+L+ ++ A      AKI DFGLAK + + + K+++    RGT LYMAPE+V ++  ES  D+WALGC+V EM +GKP WD  P V   +LL  I  G ELP+IP ++S+D KDF+ +CFV +P  R+TAEMLL+  F+SG D
Sbjct:   12 WSRGPLIGKGGFGSVYLASLKNPKSRNGYYPPVMAVKSAEVSASCSLQKEKEVFNCLNGCPFIIKCFGEETTSNKDGEMFYNVLLEYASGGNLACLIKKSDGVGLPELDVKRYTRSILEGICYIHSRGYVHCDLKPENILLVSNRAKAGEFVAKIGDFGLAKKSEKRNKKMKIDPYLRGTALYMAPETVANHVQESPCDIWALGCVVLEMLTGKPAWDLKPHVTTEELLRKIGDGYELPKIPSQISKDAKDFLKRCFVANPMFRFTAEMLLDEPFMSGVD 291          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSS---HLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENG-EKFYNLVLEYASGGTLADELKRNGG-RLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGA------AKIADFGLAKXAGESDNKVEV----RGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDD 798
            W RG  +G+G F ++Y A   SP S   + PP++A K++E   S SL+ EK+V + +  CP II+CFG + + + G E FYN++LEYASGGTLA  +K++ G  LPE DV+R+T+S+L G+ +IH  G+VHCDLK +N+L+ +         AKI DFGLAK + + + K ++    RGT LYMAPE+V ++  E   D+WALGC+V EM +GK  WD  P V + +L   I  G ELP++P E+S+D KDF+ +CFV +P  R+TAEMLL+  FVSG D
Sbjct:   28 WSRGPLLGKGGFGSVYLASLKSPKSRNGYYPPVMAVKSAEVSASCSLQKEKEVFNCLNGCPFIIKCFGEETTRDGGGEMFYNVLLEYASGGTLAGLIKKSDGVGLPELDVKRYTRSILEGIHYIHSHGYVHCDLKPENILLVSSSTKAGEFVAKIGDFGLAKKSEKRNKKRKIDPYLRGTTLYMAPETVANHVQEPPCDIWALGCVVLEMLTGKQAWDVKPDVTIEELKRKIGDGYELPKMPSEVSKDAKDFLKRCFVANPMFRFTAEMLLDEPFVSGVD 307          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESD------NKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSA-SPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLAT--EEKPNWSFSEDWVTI 1047
            M+W RG+ IG GS AT+  AK+         + A K++E   S+SL+ E+ +L  +  CPQI+   G D + ENG+ FYNL LEY SGGTL D ++  GG L E  ++ + +++L GLE++H  G VHCD+K  N+LV  DG AKIAD G AK   E            + GTPLYMAPE          +D+W++GC V EMA+G+  W  N    +  L        +P+IP  +S+  KDF+SKC  +DP +RW+A  LL+H F++ + ++ L E  +  +  +P    D   W S+              + L++ +D S     V   +R++QL     E PNWS+ + W+T+
Sbjct:    1 MDWTRGQTIGHGSSATVSMAKANRSGQ----VFAVKSAELLKSESLQREQSILSTL-KCPQIVVYKGCDITNENGKLFYNLFLEYISGGTLIDAIREGGGCLDEAMIRLYARTILLGLEYLHCNGIVHCDIKGHNILVTGDG-AKIADLGCAKRVDEVSGGTALKTTAPIAGTPLYMAPEVARGEHQGFPADIWSVGCTVVEMATGQAPW-VNVSDPVSALYQIGFSGNVPEIPSFMSKQAKDFLSKCLKRDPGERWSASELLKHDFITEEPNSALKEIISSTNVDTPTCVLDQVLWDSI--------------EELETTWDLSQESHSVSPVERIKQLTEGHGEVPNWSWDDTWITV 337          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESD-----NKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQL--ATEEKPNWS-FSEDWVTI 1047
            M+W RG+ IGRGS AT+  A++         + A K++E   S+SL+ E+ VL  +  CPQI+   G D + ENG+  YNL LEYASGGTL D ++  GG L E  ++ + +++L GLE++H  G VHCD+K  N+LV +DG AKIAD G AK   E           + GTPLYMAPE          +D+WA+GC + EMA+G+  W  N    +  L         P+IP  +S+  +DF+SKC  +DP +RW+A  LL+H F+  + + +L E  +  + +P    D   W S+              + L++ +D +   S V   +R++QL     +  +WS + + WVTI
Sbjct:    1 MDWTRGQTIGRGSSATVSMARANQSGK----VFAVKSAELSKSESLQKEQIVLSTL-RCPQIVAYKGCDITNENGKVLYNLFLEYASGGTLIDAIREGGGCLDEDMIRLYARTILLGLEYLHCNGIVHCDIKGHNILVTSDG-AKIADLGCAKRVDEVSEADWGTTTTIAGTPLYMAPEVARAEHQGFPADIWAVGCTIVEMATGQAPW-VNVSDPVSALYQIGFSGNAPEIPSFMSKQARDFLSKCLKRDPMERWSASELLKHDFIIEEPNLILKENNSSKADTPTCVLDQVLWDSM--------------EKLETTWDSTQNTSLVSPIERIKQLTEGNGKAHSWSTWGDAWVTI 336          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVF-------ADGAAKIADFGLAKXAGESD-----NKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            M+W+R K +G+GS+ T+Y A ST  +     L A K +    S +L+ E+++ ++     +++ C+G   S E G   YN++LEYA  G+L + ++  GGR+ E  V+++TK +L+GL  IH  G VHCDLK  N+LVF       +D   KIAD GLAK  GE D     +  + RGTP YM+PESV   E     D+W+LGC+V EM +G+  W +     +F  L  + G+E P+IPE +SE GKDF+ +CF  D R+RWTA+ LL   FV
Sbjct:    5 MKWLRLKNLGQGSYGTVYLAISTFTNE----LFAVKNANLEDSSTLQKERRIFERFPGTDEVVECYGYCVSKEGGVLKYNILLEYAPMGSLLNLMRDCGGRILESHVRKYTKMLLKGLSCIHSSGHVHCDLKPANILVFPRQVDRLSDIQLKIADIGLAKEPGEDDSDKLFHMYQYRGTPCYMSPESVQFAEITPALDIWSLGCIVIEMITGRVAWGNLDSKELFNKL--VYGNESPKIPEYMSESGKDFLRRCFELDHRERWTADTLLTRPFV 272          

Query:    7 WIRGKEIGRGSFATIYTAK--STSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVE--NGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVF-------ADGAAKIADFGLAKXAGESDN-KVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXI-XGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVS 789
            W R   +G+G + +++ AK  +T+    LP  +A K++    + +LK+EK+VL  + + P +I+C+G + +    +GEK YNL+LE+  G +L  ++K +G  LPE DV+++T+ V++GL+++H +G++HCD+K  N+L+            AKIADFGLA    E+ N   ++ GT  YM+PE V +  Y+   D+WALGC V EM SGKPVW   P +++   L  I    +LPQIP  +S+D KDF+ KC V++  QRW+A+ LLEH F+S
Sbjct:   21 WARCCLLGKGGYGSVFLAKRKTTTSDGDLPDKIAVKSASLENASTLKHEKRVLCDLKASPNVIKCYGDEITDTGCDGEKIYNLLLEFCCGRSLHRQIKLSGSGLPESDVRKYTRDVVKGLKYVHCRGYIHCDVKPGNILLVPGTEERSGGFVAKIADFGLAMSIYENQNWGDDLIGTYPYMSPELVKEKRYDYGVDIWALGCTVVEMLSGKPVW---PRMDVPGYLYTIGDSQDLPQIPSSISDDAKDFLGKCLVRNAAQRWSADELLEHPFLS 291          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGD--DHTVLS--EEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQLA-TEEKPNWSFSEDWVTI 1047
            M+W RG  IG GS AT+  A S         + A K+ E   S  L+ E+Q+L  + S P I+   G D + EN +  YNL LEY   GTL++ +  +GGRL E  ++ +T  VL+GL++IH  G VHCD+K  N+LV   G AKIADFG AK     +   ++ GTP++MAPE     E    SD+WALGC + EMASG   W HN    +  +        LP  P  LSE  +D + KC  +DPR+RWTA  LL+H F+ G+   H V    +E    S SP    D   W S+  SE     V        S            A +R+R L+     P W + E W TI
Sbjct:    1 MDWTRGHSIGHGSTATVSLATSIQSGD----VFAVKSVELFQSGFLQREQQILSSLTS-PFIVSYRGCDITRENSKVMYNLFLEYMPNGTLSNAIHAHGGRLDEPLIRNYTSQVLQGLDYIHLNGLVHCDIKSSNILVGPSG-AKIADFGCAKRV---EQVGQIAGTPMFMAPEVARGEEQGFASDIWALGCAIIEMASGSTPW-HNVNDPVSIIYRVGYSGHLPDFPCCLSEQARDLLDKCLRRDPRERWTASQLLKHPFLVGESNSHHVAKQIQESNSSSNSPTSILDQCFWNSLDLSESLNNLVSVPPSRESS------------AGERIRGLSLLSGMPRWDWDESWTTI 332          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKN-LDSEFDWSXRKSFVPAADRLRQLATEEKPNWSFSEDWVTIM 1050
            MEW+RGKEIGRGSFATIYTAK  +PSS LPPL+A K++ES YS S++NEK++LDQIGSCPQIIRCFG D +VE+GE+FYNL+LEYA+GGTLADELKRNGGRL E DV+RHT SVL+GL F+H KGFVHCD+KLQNVLVF +G AKIADFGLAK AGE++ K EVRGTPLYMAPESVNDNEYES +DVWALGCLVAEMASGKPVWDH+PG N+FKLLM I GDELPQIPE+L E+GKDF+ KCFVKDPR+RWTAEMLL H FVS  D  +L E K  LS SPRGPFDFPDWVS+ASSEIS  F ++ GKN L+S  DWS R+S +PA DRLR LATEE PNWSFS DWVT++
Sbjct:    1 MEWVRGKEIGRGSFATIYTAKRKNPSSQLPPLMAVKSAESYYSASVENEKRILDQIGSCPQIIRCFGDDRTVEDGEEFYNLMLEYATGGTLADELKRNGGRLAEADVRRHTNSVLKGLGFVHAKGFVHCDVKLQNVLVFDNGVAKIADFGLAKKAGEAEQKAEVRGTPLYMAPESVNDNEYESSADVWALGCLVAEMASGKPVWDHSPGANIFKLLMRIGGDELPQIPEDLCEEGKDFLEKCFVKDPRKRWTAEMLLRHPFVSNYDAVLLEETK--LSPSPRGPFDFPDWVSMASSEISSDFGDFFGKNDLNSGSDWSSRQSSIPAVDRLRLLATEETPNWSFSGDWVTVL 349          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAAKIADFGLAK----XAGESDNKVE---VRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWD--HNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVLSEEKAQLSASPRGPFDFPD---WVSVASSEISPQFVEWSGKNLDSEFDWSXRKSFVPAADRLRQL------ATEEKPNWSFSEDWVTI 1047
            W RG+ IGRGS AT+  A +         L A K++E   S  L+ E+ +L ++ SCP I+   G + S EN    YNL++EY  GGTL D ++R+GGRL E  +Q +T  +++GLE++H  G VHCD+K QN+LV A+   KIAD G AK     AG+ D+      + GTP++MAPE     E    +D+WALGC + EMA+G   W   ++P   ++++     GD LP+IP  LS  GKDF++KC  +DPR+RWTA  LLEH F+  +     +E+  + + + R P    D   W S  + E   +     G  L+S              +R+++L      A    PNW F E+W T+
Sbjct:    4 WTRGRTIGRGSTATVSLATAALSGE----LFAVKSTELSCSSFLQKEQCLLSKL-SCPNIVEYLGCNVSTENNRPMYNLLMEYVPGGTLFDTIRRHGGRLEEPAIQLYTHQIVQGLEYLHVNGLVHCDIKSQNILV-AEECVKIADLGCAKSVQIVAGDEDSATSSTIISGTPVFMAPEVARGEEQGFEADIWALGCTIIEMATGDGPWPELNDPVSALYRI--GFSGD-LPEIPTRLSNKGKDFLNKCLRRDPRERWTANQLLEHPFLE-ECLGSKTEQVREFNFTMRSPISVLDQGLWDSHEAFESPKEQSVVEGVCLNSPL------------ERIKRLIGGTCSAFSNAPNWEFDENWSTV 346          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPS---SHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKF-YNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAA---KIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTVL-----SEEKAQLSASPRGPFDFPDWVSVASSEISPQFVEWSGKNLD 933
            EW+RG+ +G+G F ++Y A    P       P ++A K++    S  L +E+ +L +   CP +I C+G D +   G    YN+ LEYA GGT+ D +K++GG  L E  V+++T+S+L+G+++IH +GFVHCDLK +N+L+   G+    KI D GLAK A     +   RGT +Y++PE+V D+  E  SD+WALGC+V +M +G+  WD   G+ +   L  +    +P++P  LS+D +DF+  CF ++P QR TA  LLEH FV+  D          +E + +S+S     D+  ++ + S         WS +N +
Sbjct:   29 EWVRGRILGQGGFGSVYLASVKKPKLGREGFPAIMAVKSALMAKSFELVSERSLLGEFRGCPFVIDCYGEDFTAGIGYNLVYNVFLEYADGGTIGDLIKQSGGSGLCELQVRKYTESILKGIQYIHERGFVHCDLKPENILLVTSGSGFVPKIGDLGLAKRAA---GERSCRGTAMYLSPETVLDSIQEKPSDIWALGCVVLKMLTGRHPWDAKAGLKLHD-LKPLIASGVPKVPGGLSKDARDFLKNCFARNPSQRLTAAKLLEHPFVTKVDEIAQVKAEPIKEVSSVSSSSNCSLDYGSFIPLGS---------WSSENAE 338          

Query:    7 WIRGKEIGRGSFATIYTAKSTSP---SSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKF-YNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAA---KIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDD 798
            W+RG+++G+G F ++Y A    P   S   P ++A K++    S  L  EK +L+ + S P +I C+G D +   G    YN+ LEYA GGT+ D +K++GG  L E  V+++T+S+L+G+++IH  GFVHCDLK +N+L    G+    KI D GL K A    +K   RGTP+Y++PE+V D   E  SD+WALGC+V +M +G+  WD   GV +  L   I    +P IP  LSE+ KDF+  CFV+DP QR TA  L+ H FV+  D
Sbjct:   31 WVRGRKLGQGGFGSVYLASVKKPKLGSEGFPVIMAVKSALMVESLELMIEKSLLETLRSSPFVIDCYGEDVTAGFGHNLVYNVFLEYADGGTVGDLIKQSGGSGLCELQVRKYTESILKGVQYIHEMGFVHCDLKPENILFVTSGSGFVPKIGDLGLTKRA---MSKRSCRGTPMYLSPETVLDRIQEKPSDIWALGCVVLKMLTGRHPWDTKAGVKLHDLKPQI-ASGVPNIPGGLSEEAKDFLKNCFVRDPSQRLTAAKLVHHPFVTEVD 298          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPSSHL---PPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSV-ENGEKFYNLVLEYASGGTLADELKRNGG-RLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAA---------KIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGV--NMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTV--LSEEKAQLSASPRGPFDFPDWVSVAS 885
            EW+RG  +G+G F ++Y      P   L   P +VA K++ +  +  L  E  +L     CP +I C+G D ++  +G   +N+ LEYA GGT+AD ++++ G  L EF V+++T+S+L+G+++IH +GFVHCDLK +N+L+ +D A          KI D GL K A +   K    GTP+Y++PE+V     +  SD+WALGC+V +M +G+  WD  PG   ++  LL  +    +P IP  LS++ KDF+  CF+ +  +R+TA MLL H FV+  D+ V  +   +   SA      D P ++ + S
Sbjct:   36 EWVRGPMLGQGGFGSVYLGFVKKPRLCLKGVPRIVAVKSTLASQAHDLMGEDILLYIFRHCPFVINCYGEDETIGADGRHLFNVFLEYADGGTMADLIEKSRGFGLREFQVRKYTESILKGIKYIHERGFVHCDLKPENILLVSDTAGSSGGARFVPKIGDLGLTKKANQKWEKPSFGGTPMYLSPEAVVYGIQQQPSDIWALGCVVLQMLTGRHPWDFTPGAVFDVRGLLTALLASRIPAIPGWLSKEAKDFLQCCFMWNTSERFTAAMLLNHPFVTKLDNGVGEVKPIEQVSSAVASSVLDCPSFIPLGS 347          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSP---SSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKF-YNLVLEYASGGTLADELKRNGG-RLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFA----DGAAKIADFGLAKXA---GESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVS 789
            EW+RG+ +G+G F ++Y A +  P   S  LP ++A K+     S  L  E+ +L   G CP +I C+G+D + +   K  YN+ +EYA GGT+ D +K++ G  L E  V+++T  +L+GL++IH +G VHCDLK +N+L+ +    D   KI DFGLAK A    +S  +   +GT +Y++PE+V     E  SD+WALGC+V EM +G+  WD   G  +  L + I   ++P +P  LSED KDF+ KCFV++P +R  A  LL H FV+
Sbjct:    2 EWVRGRMLGKGGFGSVYLATAKKPKLGSEDLPAIMAVKSGRVSKSPELLMERTLLKIFGDCPFVIDCYGSDMTADAENKCTYNVFMEYADGGTMRDLIKKSRGCGLLEPQVRKYTGCLLKGLQYIHVRGCVHCDLKPENILLVSNSDGDFVPKIGDFGLAKFAVYKKKSRKEPTCQGTAIYLSPEAVLYGNQEKPSDIWALGCVVLEMLTGRWPWDLEAGATLQDLQLLI-ASKVPTVPGWLSEDAKDFLRKCFVRNPSERLEAAKLLNHPFVT 274          

Query:    4 EWIRGKEIGRGSFATIYTAKSTSPSSHL---PPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSV-ENGEKFYNLVLEYASGGTLADELKRNGG-RLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAA---------KIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGV--NMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDH------TVLSEEKAQLSASPRGPFDFP--DWVSVASSEISPQFVEWSGKNL 930
            EW+RG  +G+G F ++Y      P   L   P +VA K++ +  +  L  E  +L     CP +I C+G D ++  +G   +N+ LEYA GGT+AD ++++ G  L EF V+++ +S+L+G+++IH +GFVHCDLK +N+L+ +D A          KI D GL K A +   K    GTP+Y++PE+V     +  SD+WALGC+V +M +G+  WD  PG   ++  LL  +    +P IP  LS++ KDF+  CF+ +  +R+TA MLL H FV+  D+       +     A  S+ P  P   P   W S  + E++ + V +S + +
Sbjct:   36 EWVRGPMLGQGGFGSVYLGFVKKPRLCLKGVPRIVAVKSTLASQAHDLMGEDILLYIFRHCPFVINCYGEDETIGADGRHLFNVFLEYADGGTMADLIEKSRGFGLREFQVRKYIESILKGIKYIHERGFVHCDLKPENILLVSDAAGSSGGACFVPKIGDLGLTKKANQKWEKPSFGGTPMYLSPEAVVYGIQQQPSDIWALGCVVLQMLTGRHPWDFTPGAVFDVRDLLTALLVSRIPAIPGWLSKEAKDFLQCCFMWNTSERFTAAMLLNHPFVTKLDNGVEEVKPIKQVSSAVASSVPDCPSFIPLGSWKSEDAEEMAQENVGFSEQEI 368          

Query:    7 WIRGKEIGRGSFATIYTAKSTSPSSHL---PPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSV-ENGEKFYNLVLEYASGGTLADELKRNGG-RLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAA---------KIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGV--NMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVSGDDHTV--LSEEKAQLSASPRGPFDFPDWVSVAS 885
            W+RG  +G+G F ++Y      P   L   P +VA K++ +  +  L  E  +L     CP +I C+G D ++  +G   +N+ LEYA GGT+AD ++++ G  L EF V+++T+S+L+G+++IH +GFVHCDLK +N+L+ +D A          KI D GL K A +   K    GTP+Y++PE+V     +  SD+WALGC+V +M +G+  WD  PG   ++  LL  +    +P IP  LS++ KDF+  CF  +  +R+TA MLL H FV+  D+ V  +   +   SA      D P ++ + S
Sbjct:   12 WVRGPMLGQGGFGSVYLGFVKKPRLCLKGVPRIVAVKSTLASQAHDLMGEDVLLYIFRRCPFVINCYGEDETIGADGRHLFNVFLEYADGGTMADLIEKSMGFGLREFQVRKYTESILKGIKYIHERGFVHCDLKPENILIVSDTAGSSGGACFVPKIGDLGLTKKANQKWEKPSFGGTPMYLSPEAVVYGIQQQPSDIWALGCVVLQMLTGRHPWDFTPGAVFDVRDLLTALLASRIPAIPGWLSKEAKDFLQCCFTWNTSERFTAAMLLNHPFVTKLDNGVGEVKPIEQVSSAVASSVLDCPSFIPLGS 322          

Query:    1 MEWIRGKEIGRGSFATIYTAKSTSPSSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKFYNLVLEYASGGTLADELKRNGGRLPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGA-AKIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWD--HNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFV 786
            M+W RG  IG GS AT+  AKS         + A K+++   S SL+ E+ +L  + S  QI+   G + S ENG  FYN+ LEYA GGTL+D ++R GG L E  ++ +T+ +L GL  +H     HCD+K QNVLV  +GA  K+AD G AK    + + + + GTP+YMAPE     +    +DVWALGC V EMA+G+  W    +P   M+++       E+P+IP  LS+ G+DFV+KC ++DP +RW+A  LL+H F+
Sbjct:    1 MDWTRGPTIGHGSSATVSIAKSHGSGE----VFAVKSAKLSQSHSLQMEQTILSTLSSA-QIVSYKGCNTSTENGTVFYNIFLEYAPGGTLSDAIRRQGGCLNEAAIRSYTRQILLGLHHLHSNQIAHCDIKGQNVLVTNNGAEVKLADLGCAKRVNFA-HGLPIGGTPVYMAPEVARGEQQGLAADVWALGCTVIEMATGRAPWPCVSDPVSAMYRIGF---SGEVPEIPSSLSKQGRDFVTKCLMRDPMERWSAGELLKHEFL 256          

Query:   19 KEIGRGSFATIYTAKSTSP---SSHLPPLVAXKASESGYSDSLKNEKQVLDQIGSCPQIIRCFGADHSVENGEKF-YNLVLEYASGGTLADELKRNGGR-LPEFDVQRHTKSVLRGLEFIHXKGFVHCDLKLQNVLVFADGAA---KIADFGLAKXAGESDNKVEVRGTPLYMAPESVNDNEYESCSDVWALGCLVAEMASGKPVWDHNPGVNMFKLLMXIXGDELPQIPEELSEDGKDFVSKCFVKDPRQRWTAEMLLEHAFVS 789
            +++G+G F ++Y A    P   S   P ++A K++    S  L  EK +L  + S P +I C+G D +   G    YN+ LEYA GGT+ D +K++GG  L E  V+++T+S+L+G+++IH  GFVHCDLK +N+L+   G+    KI D GLAK A    +K   RGTP+Y++PE+V D   E  SD+WALGC+V +M +G+  WD    V +  L   I    +P IP  LSE+ KDF+  CF+++P +R TA  LL H FV+
Sbjct:    1 RKLGQGGFGSVYLASVKKPKLGSEGFPAIMAVKSALMVESLELMMEKSLLQTLRSSPFVINCYGEDVTAGFGHNLVYNVFLEYADGGTVGDLIKQSGGSGLCELQVRKYTESILKGVQYIHEMGFVHCDLKPENILLVTSGSGFVPKIGDLGLAKRA---VSKRSCRGTPMYLSPETVLDRIQEKPSDIWALGCVVLKMLTGRHPWDAEAAVKLHDLKPQI-ASGVPNIPGGLSEEAKDFLKNCFMRNPSERLTAAKLLHHPFVT 261