MDP0000824817, MDP0000824817 (mRNA) Malus spp. (apple)

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFP--EWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYST---LEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLG-PAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLV-SNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYH 1323
            I  V   LR  K+ +  FEPRV+++GP HH K      E LK  +   F+ +S ++ E LY ++   I EL+ CY++  T++Y+ ++  LAWM  VDGCS+L FI+ Y+T   L++  IK     FA+QDLFLLENQ+P+ +L LL+    +      G+Q       +AA                         V  ++     HLL+LLR R+LG    +  EA       SFRN  EL AAGI F+ ++   LRDISF S    GFL LP +  D      FLNLIAYEMCP+  N+  VTSY+ FL S I  PED K+LR   +L N L +D+ +A+LFNEI  DLV  + +   +  +++KHY+ K   W+A+    HFSSPW +LAF+GA+ ALF   +QT+Y++   H
Sbjct:   86 IPKVPHMLRGTKDFKILFEPRVVSVGPYHHHKHDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDED--LAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGFEE-----GMQMIEQFIGSAAETDPP-------------------AVKSDNEEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILLGFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRH 475          

Query:  112 VSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNED--LWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLG---------------PAKNGREAADN------ELP-----------PSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            V + LR  ++ +K +EPRV++IGP HHGK      E +K   A +F+ DS +  E LY ++  NI+ +++CYD  +T  YD DEA LAWM  +DGC +LQFI++   +    ++  Q+ F  QDLFLLENQ+PY +L L+   +  N+D  +   I+ F+        +  +                      +++  P  HLL LLR+ +LG               P K G+ ++          P            SFR+ K+L A+GIH + S   +L D+SFKS  F G+L LP +  D      FLN++AYEMCPD  +DY +TSY+  L   I H +D K+LRS  IL+N L  DE +AQLFNEIG DLV   +   +  R+++HY  +   W+AQ   DHFS+PW ++AFI A+  LFL+ +QT+Y++
Sbjct:   69 VPQMLRGTQDFKKMYEPRVISIGPYHHGKPDLGRVEMIKPPCAQEFLADSNQDIEALYTKIRSNIETVRKCYDWSSTSEYD-DEA-LAWMMLLDGCFLLQFIRRKGKINF--LRNHQIIFVLQDLFLLENQLPYGVLKLIFEEAKFNDDSLMKKKIKEFVTKTGRPEASDEE----------------------LDEEPP--HLLHLLRSSLLGRDKRIRGSQPEQEQQPEKKGKSSSSQGGDWGFRCPWKKCKQRAIWLYSFRSIKDLKASGIHLKPSRTSVLTDVSFKSSFFHGYLKLPRIIIDDFTKKKFLNMVAYEMCPDAPDDYGITSYICLLDDLIDHADDVKELRSKNILYNLLGNDEDVAQLFNEIGNDLVDPEAYEDVKDRIQEHYNKRMNTWIAQALHDHFSTPWTIIAFIAAVLILFLTGVQTYYAL 478          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRL--AADFVNDSGRSEEFLYKEVEDNIKELKQCYDE-------KTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLE--EFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPT-THLLELLRTRMLGPAKN---GREAADNELPP------------------SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSI-IHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V+  LR+ KN EK++ P++L++GPIHH         KY+L  AA ++ ++G   E L+K++ DNI ELK  + +       K+ E +   E  L+WM FVDGCS+L  ++K    E     IK DQ+     D+ LLENQ+PY +L LL   +  + +L   +  FLD H  A    ++P +    + +   + E  + +  E    T THLL+L R  +L  + +     EA +N+                     ++R+ ++L A GI  + S      D+ F +  FA  L LP +  D  +   FLNLIAYEMCPDF+NDY + S+ +F+ S I  PED K+LRS  IL N L +DE +A  FN I  DLV N  I   +  ++ +HY +K K W+A  F  +FS+PWA++AF+ A  AL L+ IQTW+++
Sbjct:   27 IQRVAEYLRNRKNFEKHYSPKLLSVGPIHHDNTNLKLGEKYKLMWAAKYIENTGHIPEDLHKKIADNIDELKGHFGDDVLTLTGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDN--DSELIKSMMTFLDCHHWATPDESQPDKEKDMVPKGKGEGEHSVSITNESQLETPTHLLDLQRKIILTTSNSKTKSNEANNNKWSQKNSDENVKKNSKEDVKMMTYRSIQDLRAVGIRLKSSATRRPTDVDFSAGWFAAKLTLPEIVVDDTSAATFLNLIAYEMCPDFENDYGICSFAAFMDSLIDRPEDVKELRSKGILLNSLGSDEEVADFFNIISTDLVPNTKIYFEVREKIHEHYCNKCKTWIALGFHTYFSNPWAIIAFLAAFIALALTFIQTWFAV 463          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRL--AADFVNDSGRSEEFLYKEVEDNIKELKQCYDEK--TTERYD-----GDEASLAWMFFVDGCSILQFIQKYSTLEEFE--IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNED---LWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V ++LR+ KN EK++ P+ ++IGPIHH         KY+L  AA ++ ++G   E L+K++ DNI ELK  +D+   T+ R+        E  L+WM FVDGCS+L  ++K +  E +   IK DQ+     D+ LLENQ+PY++L LL     K+ED   L   +  FLD H  A    ++  +  K+ M    K E   GV + ++      L          +K  R+     +  ++RN ++L   GI+F+ S+    RDI F    F   L LP +  D  +   FLNLIAYEMCPDF NDY + S+ +F+ S I +PED K LRS  IL N L +DE +A+LFN I  DLV N  + + + +++  HY+++   W+AQ F  +FSSPWA++AFI AL AL L+ IQTW+++
Sbjct:   27 IQRVLKSLRNRKNFEKHYSPKCVSIGPIHHHNTNLILAEKYKLMWAAKYIENNGYIPEDLHKKIADNIDELKGHFDDDVLTSTRWSLAGFRSLEEKLSWMLFVDGCSLLYILEKANLNEPWHMNIKVDQLVLVMMDVLLLENQLPYQVLKLLW----KDEDESGLIESMMNFLDCHHWATPDESQSGK--KKDMVPKRKGE---GVTIRNNEANKENL----------SKKSRDEKVKMM--TYRNIQDLRDVGINFKSSKTRRPRDIDFSEGLFTAELTLPEIVVDDSSATTFLNLIAYEMCPDFHNDYGICSFAAFMDSLIDNPEDVKLLRSKEILLNSLGSDEEVAELFNIISTDLVPNADTYLEVRAKIHDHYRNRCNTWIAQGFRTYFSSPWAIIAFIAALIALVLTFIQTWFTV 425          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHG--KFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDE-ASLAWMFFVDGCSILQFIQ--KYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQD----------------------------LKFELRLGVCMEDSWPTTHLLELLRTRML---------GPAKNGREAADNELPPSFRNAK------------------------------------ELMAAGIHFRCSEGMLLRDISF--KSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLV-SNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V+  LR  K+  K++ PR+++IGPIHHG  K    E+ K   AA ++  + +  + LY+++  NI++LK+ + E     +  DE  S +WM FVDGCS+LQ ++  K    +E  +K DQ+    QD+ LLENQ+PY++L LL S    +  L   +  FL  H  +      P R  ++  +QD                            LK E R+ +  E      HLL+ LR  +L         G  K  +   ++    ++RN K                                    EL AAGI  +  +   LRD+SF  + +C    L LP +  D    P FLNLIAYEMCPDF N++ + S+++F+ S I HPED K+LR+A++LHN L +DE +A+LFN I  DLV    S  H+  ++EKHY+SK++ W+A  +  +FS+PWA++AF  AL AL L+ IQTW +I
Sbjct:   28 IQRVAHHLRDRKHFAKHYLPRLVSIGPIHHGAEKLQLGEKYKVMWAAMYLERTKQDAQTLYQKIASNIEQLKELFSEDVVRDFPDDEKLSWSWMLFVDGCSLLQILEKGKLHYPKEMNVKVDQLALVWQDVLLLENQLPYQVLKLL-SDHGNDAKLVKSMNEFLKCHHLS------PVRQEQKAKKQDMGNFKSKDEDRALTEEEYRSVCVKNEDTLKGEHRIEITQES---PIHLLDQLRRYVLDDPHEKKDTGRDKRKKNTNEDLDMITYRNKKRENSTNEDLDMTTYRNKKKEQNTNEDLDMTTYRNIQELRAAGIKLKREKSRRLRDVSFSYRWMCLCAELMLPEITVDDTTAPTFLNLIAYEMCPDFGNNFEICSFVAFMDSLIDHPEDVKELRAAKVLHNALGSDEEVAKLFNTISTDLVPDTESYSHVRCQIEKHYRSKYRTWIALGYHTYFSNPWAIIAFHAALVALVLTFIQTWLAI 503          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRL--AADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQK--YSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGI-QXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELR------------LGVCMEDSW-------------PTTHLLELLRTRML-GPAKNGREAADNELPP-----------------SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYH 1323
            IQ V+  LR  K+  K++ PR+++IGPIHHG        KY+L   A ++  + +  + LY+++  NIK+LK+ + E     +  DE  L+WM  VDGCS+LQ ++K      EE  +K DQ+    QD+ LLENQ+PY++L LL     +NE +   I + FL  H  +      P R   R   QD+  ++               VC ++               P  HLL+ LR  ++  P KN ++    +                    ++RN KEL AAGI  + S    ++D SF        L LP +  D    P FLNLIAYEMCPDF N+Y + S+++F+ S I +P+D K+LR A IL N L +DE +A LFN I  DLV N     H+  ++E+HY++K K W+A     +FS+PWA++AF  A+ A+ L+ IQTWY+I   H
Sbjct:   28 IQRVAHYLRDRKHFAKHYSPRLVSIGPIHHGAKNLLLGEKYKLMWTARYLERTNQDAQTLYQKIASNIKQLKELFAEDVIADFPDDE-KLSWMLLVDGCSLLQILEKGKLDYPEEMNVKVDQLVLVWQDVLLLENQLPYQVLKLLTGP--ENEAMLLNIMKEFLKCHHLS------PVRPNHRAKTQDMDKDITKQEDRAFTEEGCTSVCTKNESTLQGEHRVEIPQEPPIHLLDQLRRTVIHDPQKNHQDHRKKDTTSKKKKCKQNKKNEDSDIITYRNIKELRAAGISLKKSNSRRIKDTSFSCGWLYAELKLPEITVDDTTAPSFLNLIAYEMCPDFTNNYEICSFVAFIDSLIDNPDDVKELRKAGILLNMLGSDEEVANLFNTISADLVPNMEGYSHVRPQIERHYRNKCKTWIALGSHTYFSNPWAIIAFHAAVLAIVLTFIQTWYAIHPAH 476          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDE-------KTTERYDGDEASLAWMFFVDGCSILQFIQKYS--TLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAA---------------------------------GASAKPFRWYKRMM-RQDLKFELRLGVCMEDSWPTT-HLLELLR-------TRMLGPAKNGREAADNELPP-SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V   LR+ KN EK++ P++++IGPIHH        E+ K   AA ++ + GR+   L+K++ DNI ELK  + +       ++ E +   E  L+WM FVDGCS+L  ++K       +  IK DQ+     D+ LLENQ+PYE+L LL   S ++E L   ++ FL  H  A                                    S  P    K M+ ++  + E  L +  E    T  HLL+L R       T  +      ++++D ++   ++RN ++L A GI  + S+    RDI F    FA  L LP +  D  +   FLNLIAYEMCPDF NDY + S+ +F+ S I +PED K LRS  IL N L +DE +A+LFN I  DLV N  +   + +++  HY ++   W+A+ F  +FS+PWA++AFI A TAL L+ IQTW+++
Sbjct:   29 IQRVQEYLRNRKNFEKHYSPKLVSIGPIHHDNPNLKTGEKYKLMWAAKYLENIGRNPRDLHKKIADNINELKGHFSDDVLTLTGQSLEDFGSLEEKLSWMLFVDGCSLLHILEKAKLHVPGQMNIKVDQLVLVMMDVLLLENQLPYEVLKLLWKDSDESE-LIKSMKNFLKCHHWATPDNKRNRRKRRNQETSNIVPDKTGKEQHSVLITNESETPSEKEKDMVPKRKGEGEHSLSIRNESQLETPFHLLDLQRNIILITSTTKINKESWSQKSSDEKVKMMTYRNIQDLRAVGIRLKSSKTRRPRDIDFSEGLFAAELTLPEIVVDDTSAATFLNLIAYEMCPDFDNDYGICSFAAFMDSLIDNPEDVKLLRSKGILLNSLGSDEEVAELFNIISTDLVPNSETYFEVRAKIHDHYCNRCNTWIAEGFHTYFSNPWAIIAFIAAFTALVLTFIQTWFTV 487          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE-----IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLG------------PAKNGREAADNE-LPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAMPL--FLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYS 1308
            +  V   LR  ++ +K +EPRV++IGP HHGK      E +K   A  F+    +  + LY ++E  I+ +++CYD K T RY+ DEA L WM  +DG  +LQFI   ST++  +     ++  Q+ F  QDLFLLENQ+P+ +L L+   +  N      ++  +    T  G            M + L  E++L    E++   +HLLELLR+ +LG              K G+ ++    +  SFR+ KEL AAGI+ + S    L +ISFKS  F G L LP +  D      FLN++AYEMCPD   D AVTSY+ FL   I   +D K+LRS  ILHN L +DE +A++FNEIG DLV   +   + +R++KHY  +   W+A+   +HF SPW   + I A+  L ++ +QT+Y+
Sbjct:   65 LPKVPHMLRGTQDFKKLYEPRVISIGPYHHGKPHLRPGEMIKPLYAEQFLAGINQDFKDLYTKIESKIEAVRKCYDTKPTNRYN-DEA-LIWMMLLDGLFLLQFIG--STVDPRDDMSNVLRDHQINFVTQDLFLLENQLPFGVLKLIFEGA--NFQDAPPMEKTIKEFVTDFG------------MPEGLSSEIQLE---EENKEPSHLLELLRSALLGGYKKIQPKQKQEAEKKGKSSSSGGGIWESFRHIKELKAAGIYLKPSRKSFLTEISFKSHFFYGCLKLPRITIDGFTKTKFLNMVAYEMCPDAPVDQAVTSYVCFLYELIDQADDVKELRSKHILHNLLGSDEDVAKIFNEIGNDLVDPGAYGDVKARIQKHYDKRVNTWIAEGLHEHFRSPWTFTSLIAAVWILIVTGLQTYYA 467          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPE-----WEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDE-------KTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLE--EFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPT--THLLELLRTRML-GPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSI-IHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V+  L++ K+ EK++ P++++IGPIHHG          E+ K   AA ++ ++G +   L+K++ DNI ELK  + +       K+ E +   E  L+WM FVDGCS+L  ++K    E     IK DQ+     D+ LLENQ+PY +L LL   + ++E L   ++ FL  H  A                  L+  L L   +  SW    THLL+L R  +L   +K+ +    +    S+R+ + L A GI  + +     + I F    F   L LP +  D  +    LNLIAYEMCPDF+NDY + S+ +F+ S I HPED K LRS  IL N   +DE +A LFN I  + + +  I   + +++++HY ++WK W+ Q    +FS+PWA +AF+ A  AL L+ IQTW+++
Sbjct:   28 IQRVAEYLKNRKDFEKHYSPKLVSIGPIHHGNTSNANLKLGEKYKLTWAAKYIENAGLNPCDLHKKIIDNIDELKGHFSDDVLTLAGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDNNESE-LIKSMKMFLTRHPWAT-----------------LESILELLTIISFSWEKLPTHLLDLQRNIILFTQSKSPKNLESHVRKMSYRSVQSLRAVGIRLKSTATRNPQSIEFAEGWFTAKLTLPEIVVDDRSAATILNLIAYEMCPDFENDYGICSFATFMDSLIDHPEDVKLLRSKGILLNSPWSDEEVANLFNSIRTNFIPDTEIYFKVRAKIDEHYCNRWKTWIGQGLNTYFSNPWAFIAFVAAFIALALTLIQTWFTV 432          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDE-------KTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTA--AGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPT-THLLELLRTRMLGPAKNGREA------------ADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V   LRS KN E+++ P++++IGPIHH        E+ K   AA ++ ++G   E L+K++ DNI ELK  + +        + + ++  +  L+W+ F+DGCS+L  +     L    IK DQ+    +D+ LLENQ+PYE+L LL     K+ED    I+     H+     G+ A+          ++   E  + +  E    T THLL+L R  +L  + + ++             ++  +P ++R  ++L A GI  + S      D+ F +  F   L +P +  N  A    LNLIAYEMCPDF ND  + SY++ + S I HPED K LRS  IL   + +DE +A LFN IG DLV+N     ++  +L +HY +K+K W+A  F  + ++PWA++AF+ A TAL L+ IQTW+++
Sbjct:   27 IQRVQEYLRSRKNFEQHYSPKLVSIGPIHHDNPTLKLGEKYKLMWAAKYIENTGLIPEELHKKIADNIDELKGRFSDDVLTLTGNSLQGFECLDEKLSWILFMDGCSLLHILDNIMYLLPMNIKVDQLALVREDVLLLENQLPYEVLKLLW----KDEDESGLIKSMRSFHNCIYFVGSEAEK--------EKEGNGEHSVSIPNESQSETPTHLLDLQRKIILTTSNSKKKINEAKIREWRWKNSEENIPITYRGIEDLRAVGIRLKASATGRPTDVDFTAGWFTAKLTIPVIYVNNLAASTLLNLIAYEMCPDFDNDCGICSYVALMDSLIDHPEDVKVLRSKGILCT-VWSDEEVASLFNIIGTDLVANIDKYFYVQLKLREHYFNKYKTWIALGFRTYLNNPWAVIAFLAAFTALALTFIQTWFTV 443          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFP--EWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYST---LEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLG-PAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLV-SNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYH 1323
            I  V   LR  K+ +  FEPRV+++GP HH K      E LK  +   F+ +S ++ E LY ++   I EL+ CY++  T++Y+ ++  LAWM  VDGCS+L FI+ Y+T   L++  IK     FA+QDLFLLENQ+P+ +L LL+    +      G+Q       +AA                         V  ++     HLL+LLR R+LG    +  EA       SFRN  EL AAGI F+ ++   LRDISF S    GFL LP +  D      FLNLIAYEMCP+  N+  VTSY+ FL S I  PED K+LR   +L N L +D+ +A+LFNEI  DLV  + +   +  +++KHY+ K   W+A+    HFSSPW +LAF+GA+ ALF   +QT+Y++   H
Sbjct:   86 IPKVPHMLRGTKDFKILFEPRVVSVGPYHHHKHDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDED--LAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGFEE-----GMQMIEQFIGSAAETDPP-------------------AVKSDNEEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILLGFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRH 475          

Query:  688 DSWPTTHLLELLRTRMLGPAKNGR---------EAAD-NELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSI-----IHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYS 1308
            +S P  HLL+L R   LG  ++G          E  D  E+  SFRN KELM AGI  + S    LRDISF+S      L +P +  D     +FLNLIAYEM  D  +D+   SYL FL S I H +D K+L+S  IL N L T + +AQ FN +  +L SN        + I   L+ HY SK   WM Q  + +F SPW ++A++GA  ALFL+ +QT++S
Sbjct:   28 ESKPCHHLLDLFRRNFLGDERSGSPTHPENENLEVRDVKEVMASFRNVKELMDAGIRIKRSPTRHLRDISFRSNGITACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDFI--SYLRFLDSLIDHADDVKELQSIGILQNNLGTHDEVAQFFNTVSANLESNFHAYKDVRVKIRKHLQSHYNSKLTMWMTQCLDTYFGSPWTIIAWVGAALALFLTFVQTYFS 249          

Query:  787 SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSI-----IHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            SFRN KELMAAGI  + S    LRDISF+S      L +P +  D     +FLNLIAYEM  D  +D+   SYL FL S I H +D K+L+S  IL N L T E +AQ FN +  +L SN        + I   L+ HY SK K WM Q  + +F SPW ++A++GA  ALF +A+QT++S+
Sbjct:   30 SFRNVKELMAAGIRIKRSPTRHLRDISFRSNGITACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDFI--SYLRFLDSLIDHADDVKELQSIGILQNNLGTHEEVAQFFNTVSANLESNFHAYKDVRVRIRKHLKNHYNSKLKMWMTQCLDTYFGSPWTIIAWVGAALALFFTAVQTYFSV 209          

Query:  103 IQNVSRTLRS-NKNLEKYFEPRVLAIGPIHHG----KFPEWEELKYRL---AADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFA-------EQDLFLLENQIPYEILNLLMSSSIKNED--LWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPS-----------FRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLEK-------HYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            I  V R LR  +KN    F P++++IGP H+G    +F E  +++Y L    +      G++EE + +E+E   ++ +QCY    T  +D D      M  +DGC +L+ ++ Y+  E  +   D +F         ++DL  LENQ+P+ +L  L       ED  L   +  F D           P +  +  +  + +F+              H+LE+ R+  L        +   +L  S             +  EL  AG+  +  E   L DI+F+    AG L +P +  D     LFLN +AYE C D +  +  T+YL F  S I    D   L    I+++ L +D+ +A LFN++G ++V +    ++S ++++       +Y SKW+ W      D+FS+PW   + + A+  L L+  QT+Y++  Y+ P
Sbjct:   42 IYRVPRNLREVHKNA---FVPKIISIGPFHYGDPGLRFMEEHKVRYLLRLLGSRTPEKGGQAEELMSQELE---QKTRQCY----TGAFDIDSNDFVQMMVIDGCFVLELLRLYNRFEREKNVDDPIFTIRWMLRTLQRDLLKLENQLPFFVLKKLFELISLAEDPPLIDLVLTFFD--------PLLPRKNIEGNLNPEGEFD--------------HMLEVFRSTFLSSVNQDITSGCEQLKISVNVPLVQERQLIHSVTELEKAGVKLKKREDCDLLDINFQ----AGVLKIPPLYIDDNTAVLFLNFVAYEQCEDTKPFF--TNYLMFFDSLINSSADVGILHKNGIINHVLGSDQDVADLFNKLGREVVYDLDECYLSQQIKRVNNYCKTYYASKWRVWFTNLKHDYFSNPWTFFSLLAAIALLLLTTAQTYYTVYGYYSP 449          

Query:  112 VSRTLRSNKNLEKY-FEPRVLAIGPIHHG----KFPEWEELKYRLA---------ADFVNDSGRSEEFLYKEVE-DNIKELKQCYDEKTTERYDGD----EASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFA-------EQDLFLLENQIPYEILNLL--MSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAA--------DN----ELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRL-------EKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPKS 1335
            V R  +S + ++K  F P++++IGP H+     +  E  +++Y L           + V DS +    + K +  +++ E  +  ++KT E Y  D       L  M  +DGC +L+ ++ Y   +  E   D +F         ++DL  LENQ+P+ +L  L  +   + +  L   +  F D           P +  K  +  + +F+              H+L++ R+  L       + A        DN    E         EL  AG+ F+  E + L DISFK     G L +P +  D   +PLFLNL+AYE C      +  T++  F  S I    D   L    I+++ L +D+ +A LFN++G ++V +    ++S ++       ++++ SKW  W      D+FSSPW  L+ + A+  L L+  QT+Y++ +Y++PKS
Sbjct:   53 VYRVPKSMRGIQKNAFLPKIISIGPFHNKDPGLRIMEEHKMRYLLRLLESGPRENGERVEDSAQQVPQVVKAIRLEDLAESMRMLEQKTRENYSEDLQIDSDELIQMMVIDGCFVLELLRLYFKFDNEEEVEDPIFTTRWMLRTLQRDLLKLENQLPFFVLEKLYELIRLVDDPPLVDLVVTFFD--------PLLPRKNIKGKLNPNEEFD--------------HMLDVFRSTFLSSINERTKPAGWKQLQKLDNIPLVEERQLIHCVTELQEAGVRFKMREDLDLLDISFKD----GMLKIPPLYIDDNTVPLFLNLVAYEQCDQDAKPF-FTNFCMFFDSLINSHTDVGILHKNGIINHVLGSDKDVANLFNKLGREIVYDLDECYLSQQMMDVNDYCKQYFASKWHVWFTNLIRDYFSSPWTFLSLLAAIALLLLTTAQTFYAVYAYYFPKS 482          

Query:  145 EKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYS-TLEEFEIKRDQVF----------FAEQDLFLLENQIPYEILNLLM---SSSIKNEDLWHG-IQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRML--GPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPS--IIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            +K ++P+ ++ GP HHG+      E+ K R    F   S +  + L + + + +++LK  YD      +  D ++   +  VDGC +L+ ++  + T+++++   D +F          +  +D+ +LENQ+P  +L+ L+   S   K+ +L +  I  F    S  AG                      +G C+       H+L++ R  +L  GP +          PP  R  K                                    N     +FLNLIA+E       +  VTS++ F+ + I + +D   L S  I+ + L +D+A+A+LFN +  D+  +P   +  +  ++  + +  W  W A     +F +PWA+L+ I A     L+  QT ++I  Y++P
Sbjct:   41 KKAYKPQAVSFGPYHHGEEHLQTMEDHKRRALLHFFKRSDKPIKLLVESLAEVVQDLKDSYD-LLDPAWQKDTSAFLQLMIVDGCFMLEILRTATHTMDDYD-PNDPIFSDHGRLYIMPYVRRDMLMLENQLPMLVLDKLLAVESDKAKDPELINKLILKFFTTSSPEAG----------------------MGKCL-------HVLDVYRKSLLQEGPGRK---------PPGIRMKK------------------------------------NDTTESMFLNLIAFERLHVGAGN-EVTSFIFFMDNIIDNAKDVILLHSRGIIQSALGSDKAVAKLFNSLSKDITLDPDGPLYGVHKKVNDYCRKSWNEWRANLIHTYFRNPWAILSLIAAAFLFALTIAQTVFTIYPYYHP 379          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEI-----KRDQVFF-AEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAK-------ELMAAGIHFRCS----EGMLLRDISFKSLCFAGFLFLP--AMNADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIH---ISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            I  V + LR   N+E Y  PRV++IGP+HHG+      EE K R    F++++ ++ E   + +    ++ +  Y E      +        M  VD C I++ I  +S+    E       + ++F    +D+ LLENQ+P+ +L                    L ++S  A     P           L    ++    E      H ++LL   +        + + + LPP  ++ K        L  AG+ F+      +   L D+ + +    G L +P   +      LF NLIAYE C D    Y +T Y+  +   I   +D   L    I+ N L  + A+  LFN +  D  +     H   I  +L K+Y S W  W A    D+FSSPW   + I A+  L L+ IQT ++ +S + P
Sbjct:   29 IYRVPQKLRK-ANMEAY-TPRVVSIGPLHHGEEHLVAMEEHKLRYLQKFLSETRKTLEECVEIIYREEEKARGYYMESIKMSRE----EFVKMILVDACFIIEVILGFSSSHSIETGDRIYNKPRLFIDVRRDMTLLENQLPFFLL--------------------LSLYSLRAPPGPLPENQNDYAHYSFLLLSKKISSRHE----IKHFVDLLIVCL--------QPSSSSLPPESKSFKFVIPTATYLREAGVRFKLGSKDKDNDKLLDLDYNN----GVLKIPHLILQEKCESLFRNLIAYEECHDHAQTY-ITDYMYLMDHLINTTKDVNLLVRKGIISNHLGDNHAVKNLFNRLLIDTTTCKETFHFAGIYEKLNKYYDSPWNRWQATLRHDYFSSPWRGASTIAAVILLVLTLIQTVFTWMSVNLP 418          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFF--------AEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRC-SEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPS--IIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYS 1308
            I  V + LR   N+E Y  PRV++IGP+HHG+      EE K R   +F++ + ++ E   + +    K  + CY     E  +        M  VDGC I++ I  +        K D   F          +D+ LLENQ+P  +L L + S ++     +    FL +       S   F++Y +M                ++    H ++LL       +   +  +D +      +A +L  AG+ F   S+   L DI ++     G L +P +  D    PLF NLIA+E C  ++    +T Y++ +   I   +D   L +  I+ N L  + A+  LFN +  +  +     +  ++  L ++    W  W A    D+F SPW   + I A+  L L+ IQT +S
Sbjct:   29 IYRVPQKLRK-VNMEAY-TPRVVSIGPLHHGEEHLIAMEEHKLRYLQNFLHRTRKTLEECVEIISREEKTARDCY----MEPINMSSKEFVEMILVDGCFIIEVILGFQNWNGRTGKPDDRIFNKPWLIYDVRRDMTLLENQLPLFLL-LTLYSQLEVPRHQNHYDSFLLL-------SVNFFKFYSQM---------------PEAKKIKHFVDLLIVCQQPSSTRPQNRSDFKF--MIPSATQLHEAGVRFELGSKEERLLDIVYRRS--DGVLKIPRLKLDDKCEPLFRNLIAFEQC-HYRERLYITDYITLMDQLINTTKDVDVLVNKGIIENLLGDNVAVTNLFNNLLINATTGTDFYLADVTEGLSEYCDVPWNRWKAALRHDYFCSPWRGASTIAAVILLLLTLIQTIFS 411          

Query:  154 FEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRS----EEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE-----IKRDQVF-FAEQDLFLLENQIPYEILNLLMS-SSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAMP--LFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHIS---SRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHY 1326
            ++P +++IGP H G+      EE K+      +  + R     +++L + ++    E ++CY    +E    D      M  +DGC I+ F +K   +  FE     +    VF F  +DL LLENQ+P+ +L  L   + +  E+            S  + AS     +   + R D   E+    C   +    H L+LLR   + P +      D+      +   +L  AGI  +  +      + F++    G + +P +  D      F N +A+E+C      + +T+Y + L   I   +D   L    I  N   TD A+A+  N +G D+  +P   ++S   + + ++Y + W   +A     +F +PW+ ++   A   L L+ +QT+Y++  Y +
Sbjct:   60 YQPHIISIGPYHRGEPHLKMIEEHKWLYLGSLIARTQRHGLGLQDYL-RALQPLEMEARECY----SEIIHLDTHDFLEMLVLDGCFIIDFFRKIGKMHPFEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTKMPGEE------------SGPSLASLVLGFFNNTLQRPD---EILQKHC---NLKGKHFLDLLRLSFI-PEEQELGTLDHRPTHLIQCVSKLRKAGIKLKSGKADSFLTVKFRN----GVMEMPPVTIDDFLTCFFQNCVAFELCHKDCTKH-ITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVYPYFH 439          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRLAADFVNDSGRSE---EFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQD-LKFELRLGVCMEDSWPTTHLLELLRTRML---GPAKNGREAADNELPP------SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPD--LVSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIIS 1317
            I NV +TL + K     + P+ +A+GP HH +   +E  +Y+LAA             E L  ++  +   ++ CY +     ++GD  +LAWM  +D   +L+F+Q Y+      IK  +V            ++   + +L    S  + +     Q F  + +  +  +  P R  KR++  D +K  L+L   +    P   +L+     +       +N  E  +N + P      +  +  EL  +G+ F  + G +   I+F +     +L   ++  +   +  NL+AYE   +      +  Y   ++  I   EDA+ LR   I+ N+L++DE +A L+N +     L   P +  +   +  ++   W+    +F + +    W  L F+  +  L+L A+Q + S+ S
Sbjct:   36 IYNVPKTLMATK--PDCYVPQEVALGPYHHWRPELYEMERYKLAAAKRTQKHLQRVKFESLVDQLTKHEPRIRACYHKFL--EFNGD--TLAWMMAIDASFLLEFLQVYA------IKAGRVL----------TRVSSRMSHLGKEESFGDSNYVQ--QLFQIIWNLVSTCTQGPIRLLKRLLLSDPVKVILKLPWTIVSKLPGFSILKQPVEDIFFSQNKEENKPENGNNIIKPPLIEEIAIPSVSELSKSGVRFLPTNGSI-SSITFDAKMATLYLPTVSLEVNTEVILRNLVAYE-ASNASGPLIIARYTELMNGIIDTKEDAQFLRERGIILNRLKSDEEVADLWNGMNKTIRLTKVPFLDKVIEDVNNYHTGIWQVKAGKFMKRYVFGSWQFLTFLATVCILWLMALQAFCSVYS 429          

Query:  148 KYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRS---EEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFA-------EQDLFLLENQIPYEILNLLMS------SSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGR-EAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAM--PLFLNLIAYEMC-PDFQNDYAVTSYLSFLSSFITHPEDAKQLRSAR-ILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLE--KHYKSKW-KAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISY 1320
            K ++P+V++IGP H+G+      ++ K RL   F++++ +    E  L K V D   ++++ Y E+    +D     L +M  +DGC IL      S     E+  D +F         + DL LLENQ+P+ +L  L        SS  N   +H  +  +D      G+  +  R YK     DL  E  L    E    ++  +++     L   K+G   + D++  P   +AK L   GI FR        D           L +P +  D      FLN +A+E    D  N+  +T+Y+ F+   + + ED   LR+ + I+ N   ++  +++ F  I  D+V      ++++  +    Y  KW     A F   HF SPW  L+    L  + L+ +Q+  +I+SY
Sbjct:   61 KAYKPKVVSIGPYHYGEKHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD-----LMFMMVLDGCFILMVFLIMSG--NIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNPIDKE----GSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQV----QLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSK--EDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQFYTDSSNE--ITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSY 458          

Query:  715 ELLRTRMLGPAKNGREAA----DNELPP-----SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLE---KHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIIS 1317
            + L TR    A   R+ +    D E PP     +  +  +L  AG+ F+ +    +  ++F S   +G  +LP +N D     +  NL+AYE   +       T Y   ++  I   ED + LR   +L ++L++D+  A+++N +    V    +  +   +E   ++Y  +WK  + +  E +    W +LAF+ A+  L L ++Q +  + S
Sbjct:  311 DYLFTRQENEATTTRQESVSILDIEKPPLVEELTIPSVSDLHKAGVRFKPTAHGNISTVTFDSN--SGQFYLPVINLDINTETVLRNLVAYE-ATNTSGPLVFTRYTELINGIIDSEEDVRLLREQGVLVSRLKSDQEAAEMWNGMSKS-VRLTKVGFLDKTIEDVNRYYTGRWKVKIGRLVEVYVYGSWQILAFLAAVLLLMLVSLQLFSLVFS 521          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFP--EWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYST---LEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLG-PAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLV-SNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYH 1323
            I  V   LR  K+ +  FEPRV+++GP HH K      E LK  +   F+ +S ++ E LY ++   I EL+ CY++  T++Y+ ++  LAWM  VDGCS+L FI+ Y+T   L++  IK     FA+QDLFLLENQ+P+ +L LL+    +      G+Q       +AA                         V  ++     HLL+LLR R+LG    +  EA       SFRN  EL AAGI F+ ++   LRDISF S    GFL LP +  D      FLNLIAYEMCP+  N+  VTSY+ FL S I  PED K+LR   +L N L +D+ +A+LFNEI  DLV  + +   +  +++KHY+ K   W+A+    HFSSPW +LAF+GA+ ALF   +QT+Y++   H
Sbjct:   86 IPKVPHMLRGTKDFKILFEPRVVSVGPYHHHKHDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDED--LAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGFEE-----GMQMIEQFIGSAAETDPP-------------------AVKSDNEEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILLGFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRH 475          

Query:  112 VSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNED--LWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLG---------------PAKNGREAADN------ELP-----------PSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            V + LR  ++ +K +EPRV++IGP HHGK      E +K   A +F+ DS +  E LY ++  NI+ +++CYD  +T  YD DEA LAWM  +DGC +LQFI++   +    ++  Q+ F  QDLFLLENQ+PY +L L+   +  N+D  +   I+ F+        +  +                      +++  P  HLL LLR+ +LG               P K G+ ++          P            SFR+ K+L A+GIH + S   +L D+SFKS  F G+L LP +  D      FLN++AYEMCPD  +DY +TSY+  L   I H +D K+LRS  IL+N L  DE +AQLFNEIG DLV   +   +  R+++HY  +   W+AQ   DHFS+PW ++AFI A+  LFL+ +QT+Y++
Sbjct:   69 VPQMLRGTQDFKKMYEPRVISIGPYHHGKPDLGRVEMIKPPCAQEFLADSNQDIEALYTKIRSNIETVRKCYDWSSTSEYD-DEA-LAWMMLLDGCFLLQFIRRKGKINF--LRNHQIIFVLQDLFLLENQLPYGVLKLIFEEAKFNDDSLMKKKIKEFVTKTGRPEASDEE----------------------LDEEPP--HLLHLLRSSLLGRDKRIRGSQPEQEQQPEKKGKSSSSQGGDWGFRCPWKKCKQRAIWLYSFRSIKDLKASGIHLKPSRTSVLTDVSFKSSFFHGYLKLPRIIIDDFTKKKFLNMVAYEMCPDAPDDYGITSYICLLDDLIDHADDVKELRSKNILYNLLGNDEDVAQLFNEIGNDLVDPEAYEDVKDRIQEHYNKRMNTWIAQALHDHFSTPWTIIAFIAAVLILFLTGVQTYYAL 478          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHG--KFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEA-SLAWMFFVDGCSILQFIQKYSTLE--EFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFE------LRLGVCMEDSW----PTTHLLELLRTRML-----------GPAKNGREAADNELP-PSFRNAKELMAAGIHFRCSEGML-LRDISF--KSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V   LR  +N  K++ PR+++IGPIHHG  K    E+ K   AA ++  + +  + LY+++  NI++LK  + E     +  DE  S +WM FVDGCS+LQ ++K    +  E  +K DQ+    QD+ LLENQ+PY +L LL S    +  L   +  FL  H  +    +K       M + + + +      + +GV   D         HLL+ LR  +L           G  K   +  + +L   ++RN +EL AAGI  +  +    LRD+SF  + +C    L LP +  D    P FLNLIAYEMCPDF+N++ + S++ F+ S I HPED K+LR+A++LHN L +DE +A+LFN I  DLV +  S +H+  ++EKHY+SK++ W+A  +  +FS+PWA++AF  AL  L L+ IQTW++I
Sbjct:   28 IQRVPHHLRDRENFAKHYLPRLVSIGPIHHGAEKLQLGEKYKLMWAAMYLERTKQDAQTLYQKIASNIEQLKDLFAEDVIRDFPDDEKLSWSWMLFVDGCSLLQILEKGELQDPKEMNVKVDQLVLVWQDVLLLENQLPYHVLKLL-SDHEDDAKLVKSMNEFLKCHHLSPELRSKKQDIGNSMTKDEHRTQTPKSLYIIIGVLHVDMLYFHESPIHLLDQLRRYVLDDPHKKQKNETGNVKKEDQNTNEDLDMTTYRNIQELRAAGIKLKRDKSRRRLRDVSFSYRWMCLCAELTLPQITVDDTTTPTFLNLIAYEMCPDFKNNFEICSFVVFMDSLIDHPEDVKELRAAKVLHNALGSDEDVAKLFNTISADLVPDMESYLHVRRQIEKHYRSKYRTWIALGYHTYFSNPWAVIAFHAALVVLVLTFIQTWFTI 462          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHG--KFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEA-SLAWMFFVDGCSILQFIQKYSTL--EEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASA--------KPFRWY----------------KRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISF--KSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLV-SNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V+  LR  K+  K++ PR+++IGPIHHG  K    E+ K   AA ++  + +  + LY+++  NI++LK+ + E     +  DE  S +WM FVDGCS+LQ ++K      +E  +K DQ+    QD+ LLENQ+PY++L LL S    +  L   +  FL   +     S            R Y                K+   +DL          E+S  T   L++   R     +N  E  D     ++RN +EL AAGI  +  +   LRD+SF  + +C    L LP +  D    P FLNLIAYEMCPDF N++ + S+++F+ S I HPED K+LR+A++LHN L +DE +A+LFN I  DLV    S  H+  ++EKHY+SK++ W+A  +  +FS+PWA++AF  AL AL L+ IQTW +I
Sbjct:   20 IQRVAHHLRDRKHFAKHYLPRLVSIGPIHHGAEKLQLGEKYKVMWAAMYLERTKQDAQTLYQKIASNIEQLKELFSEDVVRDFPDDEKLSWSWMLFVDGCSLLQILEKGKLHYPKEMNVKVDQLALVWQDVLLLENQLPYQVLKLL-SDHGNDAKLVKSMNEFLKALTEEEYRSVCESPIHLLDQLRRYVLDDPHEKKDTGRDKRKKNTNEDLDMITYRNKKRENS--TNEDLDMTTYRNKKKEQNTNEDLDMT---TYRNIQELRAAGIKLKREKSRRLRDVSFSYRWMCLCAELMLPEITVDDTTAPTFLNLIAYEMCPDFGNNFEICSFVAFMDSLIDHPEDVKELRAAKVLHNALGSDEEVAKLFNTISTDLVPDTESYSHVRCQIEKHYRSKYRTWIALGYHTYFSNPWAIIAFHAALVALVLTFIQTWLAI 450          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRL--AADFVNDSGRSEEFLYKEVEDNIKELKQCYDE-------KTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLE--EFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPT-THLLELLRTRMLGPAKN---GREAADNELPP------------------SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSI-IHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V+  LR+ KN EK++ P++L++GPIHH         KY+L  AA ++ ++G   E L+K++ DNI ELK  + +       K+ E +   E  L+WM FVDGCS+L  ++K    E     IK DQ+     D+ LLENQ+PY +L LL   +  + +L   +  FLD H  A    ++P +    + +   + E  + +  E    T THLL+L R  +L  + +     EA +N+                     ++R+ ++L A GI  + S      D+ F +  FA  L LP +  D  +   FLNLIAYEMCPDF+NDY + S+ +F+ S I  PED K+LRS  IL N L +DE +A  FN I  DLV N  I   +  ++ +HY +K K W+A  F  +FS+PWA++AF+ A  AL L+ IQTW+++
Sbjct:   27 IQRVAEYLRNRKNFEKHYSPKLLSVGPIHHDNTNLKLGEKYKLMWAAKYIENTGHIPEDLHKKIADNIDELKGHFGDDVLTLTGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDN--DSELIKSMMTFLDCHHWATPDESQPDKEKDMVPKGKGEGEHSVSITNESQLETPTHLLDLQRKIILTTSNSKTKSNEANNNKWSQKNSDENVKKNSKEDVKMMTYRSIQDLRAVGIRLKSSATRRPTDVDFSAGWFAAKLTLPEIVVDDTSAATFLNLIAYEMCPDFENDYGICSFAAFMDSLIDRPEDVKELRSKGILLNSLGSDEEVADFFNIISTDLVPNTKIYFEVREKIHEHYCNKCKTWIALGFHTYFSNPWAIIAFLAAFIALALTFIQTWFAV 463          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRL--AADFVNDSGRSEEFLYKEVEDNIKELKQCYDEK--TTERYD-----GDEASLAWMFFVDGCSILQFIQKYSTLEEFE--IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNED---LWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V ++LR+ KN EK++ P+ ++IGPIHH         KY+L  AA ++ ++G   E L+K++ DNI ELK  +D+   T+ R+        E  L+WM FVDGCS+L  ++K +  E +   IK DQ+     D+ LLENQ+PY++L LL     K+ED   L   +  FLD H  A    ++  +  K+ M    K E   GV + ++      L          +K  R+     +  ++RN ++L   GI+F+ S+    RDI F    F   L LP +  D  +   FLNLIAYEMCPDF NDY + S+ +F+ S I +PED K LRS  IL N L +DE +A+LFN I  DLV N  + + + +++  HY+++   W+AQ F  +FSSPWA++AFI AL AL L+ IQTW+++
Sbjct:   27 IQRVLKSLRNRKNFEKHYSPKCVSIGPIHHHNTNLILAEKYKLMWAAKYIENNGYIPEDLHKKIADNIDELKGHFDDDVLTSTRWSLAGFRSLEEKLSWMLFVDGCSLLYILEKANLNEPWHMNIKVDQLVLVMMDVLLLENQLPYQVLKLLW----KDEDESGLIESMMNFLDCHHWATPDESQSGK--KKDMVPKRKGE---GVTIRNNEANKENL----------SKKSRDEKVKMM--TYRNIQDLRDVGINFKSSKTRRPRDIDFSEGLFTAELTLPEIVVDDSSATTFLNLIAYEMCPDFHNDYGICSFAAFMDSLIDNPEDVKLLRSKEILLNSLGSDEEVAELFNIISTDLVPNADTYLEVRAKIHDHYRNRCNTWIAQGFRTYFSSPWAIIAFIAALIALVLTFIQTWFTV 425          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDE-------KTTERYDGDEASLAWMFFVDGCSILQFIQKYS--TLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAA---------------------------------GASAKPFRWYKRMM-RQDLKFELRLGVCMEDSWPTT-HLLELLR-------TRMLGPAKNGREAADNELPP-SFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V   LR+ KN EK++ P++++IGPIHH        E+ K   AA ++ + GR+   L+K++ DNI ELK  + +       ++ E +   E  L+WM FVDGCS+L  ++K       +  IK DQ+     D+ LLENQ+PYE+L LL   S ++E L   ++ FL  H  A                                    S  P    K M+ ++  + E  L +  E    T  HLL+L R       T  +      ++++D ++   ++RN ++L A GI  + S+    RDI F    FA  L LP +  D  +   FLNLIAYEMCPDF NDY + S+ +F+ S I +PED K LRS  IL N L +DE +A+LFN I  DLV N  +   + +++  HY ++   W+A+ F  +FS+PWA++AFI A TAL L+ IQTW+++
Sbjct:   29 IQRVQEYLRNRKNFEKHYSPKLVSIGPIHHDNPNLKTGEKYKLMWAAKYLENIGRNPRDLHKKIADNINELKGHFSDDVLTLTGQSLEDFGSLEEKLSWMLFVDGCSLLHILEKAKLHVPGQMNIKVDQLVLVMMDVLLLENQLPYEVLKLLWKDSDESE-LIKSMKNFLKCHHWATPDNKRNRRKRRNQETSNIVPDKTGKEQHSVLITNESETPSEKEKDMVPKRKGEGEHSLSIRNESQLETPFHLLDLQRNIILITSTTKINKESWSQKSSDEKVKMMTYRNIQDLRAVGIRLKSSKTRRPRDIDFSEGLFAAELTLPEIVVDDTSAATFLNLIAYEMCPDFDNDYGICSFAAFMDSLIDNPEDVKLLRSKGILLNSLGSDEEVAELFNIISTDLVPNSETYFEVRAKIHDHYCNRCNTWIAEGFHTYFSNPWAIIAFIAAFTALVLTFIQTWFTV 487          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE-----IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLG------------PAKNGREAADNE-LPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAMPL--FLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYS 1308
            +  V   LR  ++ +K +EPRV++IGP HHGK      E +K   A  F+    +  + LY ++E  I+ +++CYD K T RY+ DEA L WM  +DG  +LQFI   ST++  +     ++  Q+ F  QDLFLLENQ+P+ +L L+   +  N      ++  +    T  G            M + L  E++L    E++   +HLLELLR+ +LG              K G+ ++    +  SFR+ KEL AAGI+ + S    L +ISFKS  F G L LP +  D      FLN++AYEMCPD   D AVTSY+ FL   I   +D K+LRS  ILHN L +DE +A++FNEIG DLV   +   + +R++KHY  +   W+A+   +HF SPW   + I A+  L ++ +QT+Y+
Sbjct:   65 LPKVPHMLRGTQDFKKLYEPRVISIGPYHHGKPHLRPGEMIKPLYAEQFLAGINQDFKDLYTKIESKIEAVRKCYDTKPTNRYN-DEA-LIWMMLLDGLFLLQFIG--STVDPRDDMSNVLRDHQINFVTQDLFLLENQLPFGVLKLIFEGA--NFQDAPPMEKTIKEFVTDFG------------MPEGLSSEIQLE---EENKEPSHLLELLRSALLGGYKKIQPKQKQEAEKKGKSSSSGGGIWESFRHIKELKAAGIYLKPSRKSFLTEISFKSHFFYGCLKLPRITIDGFTKTKFLNMVAYEMCPDAPVDQAVTSYVCFLYELIDQADDVKELRSKHILHNLLGSDEDVAKIFNEIGNDLVDPGAYGDVKARIQKHYDKRVNTWIAEGLHEHFRSPWTFTSLIAAVWILIVTGLQTYYA 467          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRL--AADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQK--YSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGI-QXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFR----NAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSN-PSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYH 1323
            IQ V+  LR  K+  K++ PR+++IGPIHHG        KY+L   A ++  + +  + LY+++  NIK+LK+ + E     +  DE  L+WM  VDGCS+LQ ++K      EE  +K DQ+    QD+ LLENQ+PY++L LL     +NE +   I + FL  H  +      P R   R   QD+  ++      ED   T      + T+     +        + PP          EL AAGI  + S    ++D SF        L LP +  D    P FLNLIAYEMCPDF N+Y + S+++F+ S I +P+D K+LR A IL N L +DE +A LFN I  DLV N     H+  ++E+HY++K K W+A     +FS+PWA++AF  A+ A+ L+ IQTWY+I   H
Sbjct:   28 IQRVAHYLRDRKHFAKHYSPRLVSIGPIHHGAKNLLLGEKYKLMWTARYLERTNQDAQTLYQKIASNIKQLKELFAEDVIADFPDDE-KLSWMLLVDGCSLLQILEKGKLDYPEEMNVKVDQLVLVWQDVLLLENQLPYQVLKLLTGP--ENEAMLLNIMKEFLKCHHLS------PVRPNHRAKTQDMDKDITK---QEDRAFTEEGCTSVCTKNESTLQGEHRVEIPQEPPIHLLDQLRRTELRAAGISLKKSNSRRIKDTSFSCGWLYAELKLPEITVDDTTAPSFLNLIAYEMCPDFTNNYEICSFVAFIDSLIDNPDDVKELRKAGILLNMLGSDEEVANLFNTISADLVPNMEGYSHVRPQIERHYRNKCKTWIALGSHTYFSNPWAIIAFHAAVLAIVLTFIQTWYAIHPAH 434          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPE-----WEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDE-------KTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLE--EFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPT--THLLELLRTRML-GPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSI-IHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            IQ V+  L++ K+ EK++ P++++IGPIHHG          E+ K   AA ++ ++G +   L+K++ DNI ELK  + +       K+ E +   E  L+WM FVDGCS+L  ++K    E     IK DQ+     D+ LLENQ+PY +L LL   + ++E L   ++ FL  H  A                  L+  L L   +  SW    THLL+L R  +L   +K+ +    +    S+R+ + L A GI  + +     + I F    F   L LP +  D  +    LNLIAYEMCPDF+NDY + S+ +F+ S I HPED K LRS  IL N   +DE +A LFN I  + + +  I   + +++++HY ++WK W+ Q    +FS+PWA +AF+ A  AL L+ IQTW+++
Sbjct:   28 IQRVAEYLKNRKDFEKHYSPKLVSIGPIHHGNTSNANLKLGEKYKLTWAAKYIENAGLNPCDLHKKIIDNIDELKGHFSDDVLTLAGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDNNESE-LIKSMKMFLTRHPWAT-----------------LESILELLTIISFSWEKLPTHLLDLQRNIILFTQSKSPKNLESHVRKMSYRSVQSLRAVGIRLKSTATRNPQSIEFAEGWFTAKLTLPEIVVDDRSAATILNLIAYEMCPDFENDYGICSFATFMDSLIDHPEDVKLLRSKGILLNSPWSDEEVANLFNSIRTNFIPDTEIYFKVRAKIDEHYCNRWKTWIGQGLNTYFSNPWAFIAFVAAFIALALTLIQTWFTV 432          

Query:  136 KNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTT-ERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE----IKRDQVFFA-------EQDLFLLENQIPYEILNLLMSSSIKNED----LWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRML--GPAKNGRE----------AADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHIS---SRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPKS 1335
            +N +K + P+ +++GP HHGK      E  K+R     +    +  E     + +  ++ + CY+   +  R +  E     M  +DGC +L+  +   T+E F      + D VF         ++D+ +LENQ+P  +L+ L+   +  ++    + H    F D       A  KP +   ++M    K    LG   E      H L++ R  +L   P  N R             D           EL  AG+ FR  +     DI FK+    G+L +P +  +     LF NLIA+E C   ++   +TSY+ F+ + I   ED   L    I+ + L +D  +A LFN +  ++V +P   H+S     + ++Y  KW    A     +F++PWA  +F  A+  L L+  Q++Y++ +Y+ P S
Sbjct:  124 ENDKKSYFPQTVSLGPYHHGKKRLRPMERHKWRALNKVLKRLKQRIEMYTNAMRELEEKARACYEGPISLSRNEFTE-----MLVLDGCFVLELFR--GTVEGFTEIGYARNDPVFAMRGLMHSIQRDMIMLENQLPLFVLDRLLELQLGTQNQTGIVAHVAVKFFDPLMPTGEALTKPDQ--SKLMNWLEKSLDTLGDKGE-----LHCLDVFRRSLLQSSPTPNTRSLLKRLTRNTRVVDKRQQQLVHCVTELREAGVKFRKRKTDRFWDIEFKN----GYLEIPKLLIHDGTKSLFSNLIAFEQC-HIESSNHITSYIIFMDNLINSSEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDPKDSHLSRLSGDVNRYYNRKWNVLKATLTHKYFNNPWAYFSFSAAVILLLLTLCQSFYAVYAYYKPNS 539          

Query:  148 KYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEE--FLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVF-------FAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKF-ELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRN---------AKELMAAGIHFRCSEGM-LLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLE--KHYKSK-WKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            K +EP++++IGP HHGK      ++ K R    FV    + EE  F+ +E+   +  L+       +E    D  +L  M  +DGC IL      S   E+    D +F           DL LLENQ+PY +L  L  +S                  T +G +   F ++   +++   F E   G+         HLL+L+R   + P  + R   D+    SF +         AK+L   GI F+  +    + DIS+ +    G L +P +  D     +FLN +A+E      +++ +TSY++F++  I    DA  L   RIL N   T++ +++ +  IG D+  +    +++   E    Y S+ +    A+F   HF SPW   +   AL  L  +A+Q +++  SY  P
Sbjct:   46 KAYEPKIVSIGPYHHGKEHLKMTQQHKRRFLKFFV---AKMEEKGFVPQELVKAVSSLEGVIRGSYSEDLGLDSENLVQMMVLDGCFILTLFFVVSGKVEYTNLDDPIFRMPWILPSIRADLLLLENQVPYVLLQTLFETS---------------KLVTCSGLNEIAFEFFNYSLQKPETFWEKHYGL------EAKHLLDLIRKTFV-PVPSQRRIKDHSSKSSFNDHEYLGFVLSAKKLHLRGIKFKPRKNTDSILDISYSN----GVLHIPPVVMDDFTASIFLNCVAFEQLYADSSNH-ITSYVAFMACLINEESDASFLSERRILENYFGTEDEVSRFYKRIGKDIALDLEKSYLAKVFEGVNEYTSQGFHVHCAEFIHTHFDSPWTFASSFAALLLLLFAALQVFFAAYSYFRP 436          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDG----DEASLAWMFFVDGCSILQFIQK---------YSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPT------THLLELLRTRMLGPA------------KNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCP-DFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPS---IIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPKS 1335
            I  V   L+ N N  K + P+ +++GP HHGK      +  K+R     +  + +      K   D ++EL    +EK    Y+G           M  +DGC +L+  +          Y+  +     R  +   ++D+ +LENQ+P  +LN L+       +L  G +    + +  A     P       + +  + +L   +  + S+         H L++ R  +L  +                  AD           EL  AGI FR  +     D+ FK+    G+L +P +  +     LFLNLIA+E C  D  ND  +TSY+ F+ + I   ED   L    I+ + L +D  +A LFN +  ++V +     +  +S  + ++Y  KW AW A     +F++PWA+++F  A+  L L+  Q++Y++ +Y+ P S
Sbjct:  105 IYRVPYYLQENDN--KSYFPQTVSLGPYHHGKKRLRSMDRHKWRAVNRVLKRTNQG----IKMYIDAMREL----EEKARACYEGPLSLSSNEFIEMLVLDGCFVLELFRGAVEGFTELGYARNDPVFAMRGSMHSIQRDMVMLENQLPLFVLNRLL-------ELQLGTRNQTGLVAQLAIRFFDPLMPTDEPLTKSGQSKLENSLARDKSFDPFADMGELHCLDVFRRSLLRSSPKPEPRLTRKRWSRNTRVADKRRQQLIHCVTELKEAGIKFRRRKTDRFWDMQFKN----GYLEIPRLLIHDGTKSLFLNLIAFEQCHIDSSND--ITSYIIFMDNLIDSHEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDTEDSYLSRLSIEVNRYYDHKWNAWRATLKHKYFNNPWAIVSFCAAVILLVLTFSQSFYAVYAYYKPPS 531          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLY----KEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYST-LEEFEIKRDQVFFA--------EQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGR------------EAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCP-DFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPS---IIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPKS 1335
            I  V + L+ N N + YF P+ +++GP HHG       +  K+R A + V    + +  +Y    KE+ED  +    CY+       D      + M  +DGC +L+  +       E    R+   FA        ++D+ +LENQ+P  +LN L+   +        +             + +P       + QD  F        +      H L++ R  +L P  N                AD           EL  AGI FR  +     DI FK+    G+L +P +  +     LF NLIA+E C  D  ND  +TSY+ F+ + I   ED + L    I+ + L  D  +A LFN +  ++  +P    +  +S++++++Y  KW    A     +F++PWA  +F  AL  L L+  Q++++   Y  P S
Sbjct:  141 IYRVPQYLQEN-NKKSYF-PQTVSLGPFHHGNKHLLPMDRHKWR-AVNMVMARTKHDIEMYIDAMKELEDRARA---CYEGPI----DLSSNKFSEMLVLDGCFVLELFRGADEGFSELGYDRNDPVFAMRGSMHSIQRDMVMLENQLPLFVLNRLLEIQLGKRHQTGLVSRLAVRFFDPLMPTDEPLTKTDDSLEQDKFFN----PIADKDKGELHCLDVFRRNLLRPCSNPEPRLSRMRWSWRTRVADKRQQQLIHCVTELREAGIKFRTRKTDRFWDIRFKN----GYLEIPKLLIHDGTKSLFSNLIAFEQCHIDSSND--ITSYIIFMDNLIDSSEDVRYLHYCGIIEHWLGNDYEVADLFNRLCQEVAFDPQNSYLSQLSNKVDRNYSRKWNVLKAILKHKYFNNPWAYFSFFAALVLLVLTLFQSFFTAYPYFNPPS 564          

Query:  136 KNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE-----------IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQD---LKFELRLGVCMEDSWPT-----THLLELLRTRMLGPAKNGREAADNELPPSFRNAK-------ELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPS---IIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPKS 1335
            +N +K + P+ ++IGP HHGK      E  K+R     +  +  + E     +++  +E + CY      +   +      M  +DGC +L+  +   T++ F+            KR  +   ++D+ +LENQ+P  +L+ L+           G+Q      +      A   R++K +M       K E  L    E S         H L++    ++  ++   +    E        +       EL  AG++F   E   L DI FK+    G+L +P +  +     LF NLIA+E C   Q+   +TSY+ F+ + I   +D   L    I+ + L +D  +A LFN +  +++ +P    +  +S  + ++Y  KW +  A   + +F++PWA  +F  A+  LFL+  Q+++++ +Y+ P S
Sbjct:  101 ENDKKSYLPQTVSIGPYHHGKVHLRPMERHKWRAVNMIMARTKHNIEMYIDAMKELEEEARACYQGPIDMKNSNEFTE---MLVLDGCFVLELFK--GTIQGFQKIGYARNDPVFAKRGLMHSIQRDMIMLENQLPLFVLDRLL-----------GLQTGTPNQTGIVAEVA--VRFFKTLMPTSEVLTKSERSLD-SQEKSDELGDNGGLHCLDVFHRSLIQSSETTNQGTPYEDMSMVEKQQQLIHCVTELRGAGVNFMRKETGQLWDIEFKN----GYLKIPKLLIHDGTKSLFSNLIAFEQCHT-QSSNNITSYIIFMDNLINSSQDVSYLHHDGIIEHWLGSDSEVADLFNRLCKEVIFDPKDGYLSQLSREVNRYYSRKWNSLKATLRQKYFNNPWAYFSFSAAVILLFLTFFQSFFAVYAYYKPLS 509          

Query:  154 FEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKEL-KQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFA------EQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSE----GMLLRDI----SFKSLCFA-GFLFLPAMNADA-MPLFL-NLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRLEK---HYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            +EPRV++IGP H G+      EE K+R     +  +       Y +   N++E+ ++CY E  T   D +E +   M  +DGC +L+  +K + L  FE     V  A       +D   LENQIP+ +L  L + +  + +           + T A   +  F ++  MM +  +   R            HLL+LLR+  +         ++   PP+    KE M + I    S+    G+ LR++    SF  + F  G + +PA+  D  M  FL N +AYE C         T+Y + L       +D + L    I+ N   TD  LA+  N +G D+  + +  ++    E+   +YKS W    A F   +F+SPW+ ++ + AL  L LS IQT Y++
Sbjct:   62 YEPRVVSIGPYHRGQTQLKMIEEHKWRYLNVLLTRTQNLTLEDYMKSVKNVEEVARECYSE--TIHMDSEEFNE--MMVLDGCFLLELFRKVNNLVPFEPNDPLVAMAWVLPFFYRDFLCLENQIPFFVLETLFNLTRGDNE-----------NETNASLQSLAFAFFNNMMHRTEEDLARF-----KELRAKHLLDLLRSSFI-------PESELHTPPATNPGKEKMPSHIIHSISKLRRAGIKLRELKDAESFLVVRFRHGTIEMPAITVDDFMSSFLENCVAYEQC-HVACSMHFTTYATLLDCLTNTYKDVEYLCDQNIIENYFGTDTELAKFVNSLGRDVAFDITQCYLKDLFEEVNEYYKSSWHVEWATFKFTYFNSPWSFVSALAALVLLVLSVIQTIYTV 442          

Query:  136 KNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDG----DEASLAWMFFVDGCSILQFIQKYSTLEEFE----IKRDQVF-------FAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRML---GPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISS---RLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            +N  K + P++++IGP HHG       E  K+R A + V    + +  +Y    D +KEL    +EK    Y G    +      M  +DG  I++  +   T E F+       D VF          +D+ +LENQ+P+ +L  L+   ++  D+   +   L           +PF       R+ L  E  L           H L++LR  +L   G +       + +         EL  AG+ F   E     DI FK+    G+L +P +  +     LFLNLIA+E C   ++   +TSY+ F+ + I   ED   L    I+ N L +D  ++ LFN +G +++ +P+  ++S+    +  +Y+ KW    A     +F++PWA  +FI A+T L  +  Q+++++ +Y  P
Sbjct:  115 ENDTKSYMPQIVSIGPYHHGHKHLMPMERHKWR-AVNMVMARAKHDIEMYI---DAMKEL----EEKARACYQGPINMNRNEFIEMLVLDGVFIIEIFK--GTSEGFQEIGYAPNDPVFGMRGLMQSIRRDMVMLENQLPWSVLKGLLQ--LQRPDVLDKVNVQL----------FQPFFQPLLPTREVLTEEGGL-----------HCLDVLRRGLLQSSGTSDEDMSMVNKQPQQLIHCVTELRNAGVEFMRKETGHFWDIEFKN----GYLKIPKLLIHDGTKSLFLNLIAFEQC-HIKSSKKITSYIIFMDNLINSSEDVSYLHHYGIIENWLGSDSEVSDLFNGLGKEVIFDPNDGYLSALTGEVNIYYRRKWNYLKATLRHKYFNNPWAYFSFIAAVTLLIFTFCQSFFAVFAYFKP 499          

Query:  133 NKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDN-----IKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQ-FIQKYSTLEEFEIKRDQVF-------FAEQDLFLLENQIPYEILNLLM------SSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQ-----DLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAAD----------------NELPPS-----------------FRNAKELMAAGIHFRC-SEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDL---VSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            NK  +  +EPRV+++GP HHGK      EE K R    F++++ R      K V+ N     +  L++   +  +E    D   L  M  +DGC IL  F+     +   EI+ D +F           DL LLENQ+P+ +L  +        SS  NE ++H     L   +T          W K    +     DL   + +    ++   + HLL+ +  R +   +  ++  D                  +P S                   +A++L   GI F+   +   L DI  K       L +P +  D   + + LN +A+E    +     +TSY++F+   +    DA  L    IL N   + + +++ F  +G D+   +    +  I   + K+  S W    A F   HF SPW  L+   ALT + L+ IQ +++   Y +P
Sbjct:   58 NKKYKAAYEPRVVSLGPYHHGKKNLQMIEEHKLRFLKIFMDEAKR------KGVDTNGLIKAVSVLEEDIRDSYSESLYSDGKKLIEMMVLDGCFILMIFLVVAGVVSHSEIENDPIFAIPWILPAIRNDLILLENQVPFFLLQTIFDRSKIEKSSGLNEIIFHFFNYSLQKSNTF---------WLKHQKVEANHLLDLIRNIYMPDVPKEEKKSNHLLDCMMIRKICMPRESKQELDVMLKKGKQEVDISMLEEGIPKSDSLEEEDSTTGRHHLKMVLSARKLQLKGIKFKARKKAETLMDIRHK----GKLLQIPPLILDDFLIAVLLNCVAFEQYYSYCTKQHMTSYVAFMGCLLKSEADAMFLSEVGILENYFGSGDEVSRFFKVVGKDVLFDIDESYLAGIFEGVNKYTSSGWHVQWAGFKHTHFDSPWTALSSCAALTLVILTIIQAFFAAYGYFHP 502          

Query:  139 NLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQK---------YSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPT------THLLELLRTRMLGPAKNGR----EAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHISSRL-------EKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPKS 1335
            N +K + P+ +++GP HHG+      E  K+R     +  + +  E     + +  ++ + CY+       +        M  +DGC IL+ +Q          Y   +     R  +   ++D+ +LENQ+P  +LN L+       +L  G Q          G      R++  +M              E+S P        H L++    +L P  +G+      AD  L        EL  AG  F+ ++     DI F +    G+L +P +  +     LFLNLIA+E C   ++   +TSY+ F+ + I  PED   L    I+ + L ++  +A +FN++  ++V +   I++S  L       +++Y  K  +        +  +PWA L+F  A+  L L+  Q++++  +Y  P S
Sbjct:  190 NDKKSYFPQTVSLGPYHHGRQQTQSMECHKWRAVNMVLKRTNQGIEVFLDAMIELEEKARACYEGSIVLSSN----EFTEMLLLDGCFILELLQGVNEGFLKLGYDHNDPVFAVRGSMHSIQRDMIMLENQLPLFVLNRLL-------ELQPGTQ-------NQTGLVELVVRFFIPLMPT-------AETLTENSPPRGVSNGELHCLDVFHRSLLFPRSSGKANYSRVADKHLQRVIPTVTELRDAGFKFKLNKTDRFWDIKFSN----GYLEIPGLLIHDGTKSLFLNLIAFEQC-HIESSNDITSYIIFMDNLIDSPEDISYLHHCGIIEHSLGSNSEVADMFNQLCQEVVFDTKDIYLSQLLIEVHRCYKQNYSRKLNSLKTTLILKYLDNPWAYLSFFAAVILLILTFSQSYFAAYAYFNPSS 588          

Query:  127 RSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDG----DEASLAWMFFVDGCSILQFIQ-KYSTLEEFEIKRDQVFFA--------EQDLFLLENQIPYEILNLLMSSSIKNEDLWH-----GIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGRE------------AADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAM--NADAMPLFLNLIAYEMCP-DFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDL---VSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPKS 1335
            +S+KN   YF P+ +++GP HHG       +  K+R     +  + +  E       D +KEL    +E+    Y+G           M  +DGC +L   +  Y    +    R+   FA         +D+ +LENQ+P  +LN L+   +  +          ++ F  +  T   ++       +     + KF        +      H L++ R  +L P+                  AD           EL  AGI F+  +     DI FK+ C    L +P +  +     LF NLIAYE C  D  ND  +TSY+ F+ + I   ED + L    I+ + L  D  +A +FN +  ++   + N  +  +S++++++Y  KW    A     +FS+PWA  +F  A+  L L+  Q++++   Y  P S
Sbjct:  124 KSDKN--SYF-PQAVSLGPYHHGDEHLRPMDYHKWRAVNMVMKRTKQGIEMYI----DAMKEL----EERARACYEGPIGLSSNKFTQMLVLDGCFVLDLFRGAYEGFSKLGYDRNDPVFAMRGSMHSIRRDMLMLENQLPLFVLNRLLELQLGTQYQTGLVAQLAVRFFNPLMPTYMSSTK-----IENSQENNNKF---FNPIADKEKEELHCLDVFRRSLLQPSLKPDPRLSRSRWSRKPLVADKRQQQLLHCVTELREAGIKFKRRKSDRFWDIQFKNGC----LEIPKLLIHDGTKSLFSNLIAYEQCHIDSTND--ITSYIIFMDNLIDSAEDIRYLHYYDIIEHWLGNDSEVADVFNRLCQEVAFDLENTYLSELSNKVDRYYNRKWNVLKATLKHKYFSNPWAYFSFFAAVILLLLTLFQSFFTSYPYFKPPS 539          

Query:  100 IIQNVSRTLRSNKNL-EKYFEPRVLAIGPIHHGKFP-----EWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE----IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDM-----------HSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAA---DNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSII-HISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            I   V R  R N +  E  + P V++IGP HH   P     E + LK  +   F N+SG++ E LY +VE+     K+CYDE++T+   GD+A    M  +DGC ILQFI  +  L +F+      R   +F ++DLFLLENQIPYE+L  LMS    + +    ++ F+D                 G   + + W       +   E+   V  E   P  HLL+    R +G ++     +   D +   S+R+  EL + GIHF  S+  +  DI +KS    G + LP +  D     L LNL+A+E CP     + VTSY+ F+ S I HPED K+LR   IL N L +D+ +A LFNEI   +V +P+   ++ S +EKH K+  K W A++  DHFSSPW  LAF GA+ AL L+ IQT+ ++
Sbjct:   41 ICHRVPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVQQFANESGKTREVLYSKVEELAVSAKKCYDERSTKDL-GDKA-FTEMMLLDGCFILQFI--FCFLHDFQNLKLSNRVLAYFVKRDLFLLENQIPYEVLKSLMSLRFGDAEGKKLMEDFMDDVRGLPRDKSRDKENGKGLDCRFWSWRPAPKMNNQPGEIPQ-VPGEIPQPV-HLLDFFHNRFMGGSRGQENLSLKGDGQWS-SYRSVMELKSVGIHFMPSKTDMYTDILYKSTMRGGTVTLPRIVIDDSTKSLLLNLMAHEACPGPAEGFGVTSYVYFMDSLIDHPEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWAAEWLNDHFSSPWTFLAFFGAIFALVLTFIQTYKTL 464          

Query:  112 VSRTLRSNKNL-EKYFEPRVLAIGPIHHGKFP-----EWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE----IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLD-MHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGP--AKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSII-HISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            V R  R N +  E  + P V++IGP HH   P     E + LK  +   F N+SG++ E LY+ V +     ++CYDE +T+   GD A    M  +DGC ILQFI  +  L + +      R   +F ++DLFLLENQIPY++L  LMS           ++ F+D +     G S                        ME++    HLL+    R +G    +N     D++   S+R+  EL + GIH   S+  +  D+ +KS    G + LP +  D     L LNL+A+E CP     + VTSY+ FL S I H ED K+LR   IL N L +D+ +A LFNEI   +V +P+   ++ S +EKH K+  K W+A++  DHFSSPW  LAF GA+ AL L+ IQT+ ++
Sbjct:   22 VPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVEQFANNSGKTREDLYRNVAELASSARKCYDEGSTKNV-GDNA-FTKMMLLDGCFILQFI--FCFLHDSQKLKLSNRVLAYFVKRDLFLLENQIPYKVLTSLMSLGFDGNKGQELMENFMDEVRGLPRGKSGD----------------------MENNNQPAHLLDFYHNRFMGKRGQENPSRKGDSQW-SSYRSVMELKSVGIHLMPSKTDMYTDLRYKSTMRGGTVTLPRIVIDDCTKSLLLNLMAHEACPGSAEGFWVTSYVCFLDSLIDHSEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWVAEWLNDHFSSPWTFLAFFGAIFALVLTFIQTYKTL 410          

Query:  154 FEPRVLAIGPIHH----GKFPEWEELKYRLAADFVNDSGRSE-EFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWH--GIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIH--ISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISY 1320
            ++P V++IGP H+     K  E E+LK ++A +FV DS   + E LY EV    +  K+ Y+  +   +D ++ +   M F+DGC ILQFI+      + ++   Q+   +QDL LLENQ+P+ +L  LMS     +D      I  FL +         +P  W                     SW       L++  +   +K G+   +      + +AK+L   GIHF+ S+   L D+ F S  F   L +P++  +     + LNL+AYE    F +D  VTSY+ F+ S I   ED K LRS  IL N L  D+ +A LFN+IG  L  N +I++  +  ++     S WK W+A++ + +FSSPWA +AF+ A   L L+A QT+Y++  Y
Sbjct:   87 YKPSVVSIGPYHYKDRQNKLHEVEKLKVQMAREFVLDSKIKDIEILYSEVAKVAENAKRFYEGSSISCFDDEQFTR--MMFLDGCFILQFIRGVMD-NKLDMSDQQIILVKQDLLLLENQLPFSVLKSLMSLKNDGDDRGKEININDFLLLQILQQSDQRRPV-WVL-------------------SW-------LVKGNLFPKSKLGKRGHN-----LYYSAKDLQKVGIHFKPSKTSTLMDVKFVSSIFYATLKIPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLIDDAEDVKVLRSKGILTNYLGPDQKVADLFNQIGRSLEPNTNIVYNDVKRKINVSCDSTWKKWIAEWLQTYFSSPWAFIAFVAAAAVLVLTATQTYYTVYPY 450          

Query:  100 IIQNVSRTLRSNKNLEKYFEPRVLAIGPIHH----GKFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQ-VFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIH-ISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYS 1308
            +I  V   L+ ++N +KY++P V++IGP H+     K  E E+LK ++A +FV  S +  E LY EV    +  K+ Y+  +   +D ++     M F+DGC ILQFI+  ST +  +   DQ +F  +QDL LLENQ+P+ +L  LMS +   +D  HG++   D  S      +   R  + ++   +K  L              LL L+ T +  P                    +L   GI+F+ S+   L D+ F S  F   L LP++  +     + LNL+AYE    F +D  VTSY+ F+ S I   ED K LRS  IL N L  D+ +A LFN+IG     N ++ + +   +     S WK W+A+  + +FSSPWA +AF+ A T L L+A QT+Y+
Sbjct:   70 MIPKVPDNLKDDEN-KKYYKPSVVSIGPYHYKDRQNKLHEAEKLKVQMAREFVLYSKKDMEILYSEVAKVAENAKRFYEGSSIRCFDDEQ--FTQMMFLDGCFILQFIRCVSTTDNIKNMSDQQIFHVKQDLLLLENQLPFPVLKSLMSLTPDGKD--HGMKIINDFLSLQILQQSNHQR--RPVLTWLVKGYL--------------LLLLIYTTVAYPFH------------------DLQKVGIYFKPSKTNTLMDVEFVSSIFYATLKLPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLINDAEDVKVLRSNGILINYLGPDQKVADLFNQIGHSREPNTNVYNDVKGEINLSCDSIWKKWIAECLQTYFSSPWAFIAFVAAATGLVLTATQTYYT 440          

Query:  145 EKYFEPRVLAIGPIHHGKFP---EWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFE---IKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDM--HSTAAGAS--------AKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIH-ISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            +K +EP+V++IGP +HGK     E E+ K  +   FV  S +  E +Y+ V D  ++ ++ Y E  + + D D      M F+DGC ++QF+  Y  L + E   +         +DL LLENQ+P+ +L  LM     +++   G++   D   H  A            +K FR  K + R+ L +  +    M + +   HLLEL     +   KN    +       +  A EL   GIHF+ S+     D+ FK    AG L +P +  D     + LNL+AYE C        VTSY+ F+ S I HPED + LRS  IL   L ++E +A+LFNE+   LV NP   + + + +E H+++  K W+A+  + +FSSPW+ +  + A   + L+AIQ+++++
Sbjct:   31 KKCYEPKVVSIGPYYHGKLDRLQEMEKSKCNMVRGFVQQSKKLIEDVYQTVVDVAEDARRYYVEDESVKLD-DMTEFTRMMFLDGCFVIQFM--YCLLRDHENLKMSSHAAALVTRDLLLLENQLPFLVLRSLMKLRFGSDE--EGMKLIKDFIKHIRAMPRQRESCWKKISKFFR--KTIPRRALNYSAK-DPAMGEYYGAGHLLELFHMHFVD--KNFSVDSSKTSLYRYHPAMELRTVGIHFKPSKARQFTDVQFKPTWLAGRLKIPPLTIDESTKSMLLNLVAYEACLGDNKKLWVTSYICFMDSLIDHPEDVRVLRSQGILLVTLGSEEEVARLFNEVAKYLVPNPHAFNKVKNDIESHFRNTIKRWVAEHVDTYFSSPWSFITLVAASLTIALTAIQSYFTL 428          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQ-KYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDM--HSTAAGASAKPFRWYKRMMRQDLKFELRLGVCM----EDSWPT--------THLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAM--PLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNP-SIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            I  V R LR  ++ +K ++P +++IGP HHGK    + E+LK    + FV+DSG   E  Y +V +   + ++CY E +T+ +D ++     + F+DGC ILQFI       E+ ++   QV   ++DL LLENQ+P++++  LM+      +   G +   D   H  A     + F   K M++   KF    G C+    + +W           HLL LL T  +        +  +    S+R++K+L   GI FR +      D+ FKS      L LP +  +     + LNLIAYE C D   +  VTSY  FL S I   ED K L+S  +L N    ++ +A LFN++  +LV NP +   +  R+E   KS  K W+A++   +FSSPW+ +A + A   + L+ IQ++++I
Sbjct:    6 IPKVPRLLRQIQSNQKCYDPSLVSIGPYHHGKPELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEK--FTQIMFLDGCFILQFIFFLLRRPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGEEGGGNKLINDFIRHIRALPPQQESF---KEMIK---KFA---GKCIWKQPQKTWGNKETEEHQPVHLLGLLHTDHINKEACSHCSTRSCDWYSYRSSKDLRKVGIRFRPNWTNAYSDVEFKSSVRGSRLILPPITIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVL-NIFVREQEVADLFNQMSRNLVPNPYAYSDVKRRIELDRKSIIKKWVAEWMHTYFSSPWSFIALVAATFTIVLTGIQSYFAI 416          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQ-KYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCM-------------EDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAM--PLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNP-SIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            I  V R LR  ++ +K ++P +++IGP HHGK    + E+LK    + FV+DSG   E  Y +V +   + ++CY E +T+ +D ++     + F+DGC ILQFI       E+ ++   QV   ++DL LLENQ+P++++  LM+      +   G    ++       A        K M++   KF    G C+             ED  P  HLL LL T  +        +  +    S+R+AK+L   GI FR +      D+ FKS      L LP +  +     + LNLIAYE C D   +  VTSY  FL S I   ED K L+S  +L N    ++ +A LFN++  +LV NP +   +  ++E   KS  K W+A++  D+FSSPW+ +A + A   + L+ IQ++ +I
Sbjct:   46 IPKVPRLLRQIQSNQKCYDPSLVSIGPYHHGKPELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEK--FTQIMFLDGCFILQFIFFLLRRPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGE-GGGRNKLINDFIRHIRALPPRKESIKEMIK---KFA---GKCIWKQPKKTWGNKETEDHQPV-HLLGLLHTDHINKEACSHCSTRSSDWYSYRSAKDLRTVGIRFRPNWTNAYSDVEFKSSFRGSRLILPPVTIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVL-NIFVREQEVADLFNQMSRNLVPNPYAYSDVKRQIELDRKSIIKKWVAEWLHDYFSSPWSFIALVAATFTIVLTVIQSYVAI 456          

Query:  100 IIQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTL-EEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNE-----DLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTT-------------HLLELLRTRMLGPA-------KNGREAADNELPPSFRN----AKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNP-SIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAF-IGALTALFLSAIQTWYSII 1314
            II  V  T R  +N    ++P V++IGP HHGK    E E+ K   A+ FV +S  + + ++ +VE      ++CY E +T++++  E S   M F+DGC IL F    S   E+ ++    V    +DLFLLENQ+P+E+L  LMS     +     DL+     F  + S      +   +  K +      F   L +      P +             HLLEL   + +  +       K+ +    ++   S+      AK+L  AGIHF+ S+  L  D+SF     AG L++P +  D    PL LNL+AYE C    +D+ VTSY+ F+ S I H +D K+LRS  IL + L +D+ +A+LFNEI   LV NP +   +   +E HY++  K W+      H+  P     F    +  L ++AI+ + S++
Sbjct:   46 IIPRVPPTFRKIENNSGCYDPSVVSIGPYHHGKPELKEMEDNKVTFASQFVMESQVAPDTMFCKVEGVASNARKCYTEDSTQKFEDKEFSQ--MMFLDGCFILHFFFCLSEQPEKLKMSNHHVSLVARDLFLLENQLPFEVLLELMSLRFNIQGGERVDLFEPF--FKHIRSMPPRRESCREKLSKNLATISSFFRSLLKLFSSTDHPKSPTNELTAIHRKPAHLLELFHNKFVARSIIDAAGVKDHKSWYKDDSRKSWSGRYYPAKDLRKAGIHFKPSKTSLFTDVSFTPTLLAGRLYIPPLRIDDSTKPLLLNLVAYEACLGTCDDW-VTSYVCFMDSLIDHHKDVKELRSKGILISTLGSDKQVAELFNEISDYLVPNPYAYSKVKRDIENHYRNGIKRWIL-----HYKGPTYTFIFKYSFIFGLIVTAIKAYVSVV 476          

Query:  112 VSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRS-------EEF--LYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQ-KYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDL------WHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCME---DSWPTTHLLELLRTRMLG----PAKNGREA-----ADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNP-SIIHISSRLEKHYKSKWKAWMAQFFEDHFSSP-WAMLAFIGALTALFLSAIQTWYSII 1314
            V  T+R  K  E+ ++P +++IGP H+GK    E ++LK   A  FV D           E++  +Y+ VE     +++ Y E  + +   +E   A M F DGC ILQF+       E+ ++    V    +DLFLLENQ+P+E+LN L       E++      +  I+       +    + K      ++ R+ L      G   E      P  HLLEL     +G    P  + R++     +       +  AKEL   GIHF+ S+  L  D+ F+    AG L++P ++ D    PL LNL+AYE      +D+ VTSY+ F+ S I +PED  +LR+  IL + L  D+ +A+LFN+I   LV NP + + + S +E HY++ +K W+      H+  P ++ +     +  L +SAI+ +  I+
Sbjct:   69 VPSTIRQIKQNEECYDPSLVSIGPYHNGKDELKEMQKLKVSFARQFVKDCVNDVNQERYKEKYQEMYRRVEQVASRVRKYYIENESSQLKNEE--FAQMMFFDGCFILQFLFCLLKQPEKLKMSSHDVVLVARDLFLLENQLPFEVLNELTRLRFGGENMELFEAFFKHIRSMPTQRESCREKTKKKLLTISKLFRRILLSTNPKGQESEMTAPRKPAAHLLELFHLTFVGSKDVPDASTRKSWYRDESRKTWSGRYFPAKELRNVGIHFKPSKTSLFTDVEFRRTVLAGRLYIPPLSIDDSTKPLLLNLVAYEAFLGAPHDW-VTSYVCFMDSLIDNPEDVNELRTKGILFSTLGNDKQVAELFNQISDYLVPNPYAYVEVKSAIESHYRNGFKRWIL-----HYKGPIYSSVLKYSFMYGLIVSAIKAYVVIV 495          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTL-EEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLW--HGIQXFLDM--HSTAAGASAKPFR-----WYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRN------------AKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNP 1143
            +  V  T R  +  +K ++P ++++GP HHGK    E EELK+ +A  FV D     E ++ +V++      +CY E    +++ D+     M F+DGC ILQF+  +    E  +I         +DLFLLENQ+P+ +L  LMS   K  D     G++ F D   H  A     +  R     ++ +++ + L     L     D     HLLE    + +G   N    +D+    S++             A+EL   GIHF+ S+     D+ FK    AG L++P ++ D     L LNL+AYE   D   D+ +TSY+ F+ S I HPED K+LRS  IL   L +D+ +A+LFNEI  ++V NP
Sbjct:   48 VPRVPSTFRKIEQNKKCYDPSMVSLGPYHHGKQELKEMEELKFPMARQFVRDCEMPFEAMWSKVKELKIAASKCYVEDMIAKFNKDD-QFNQMMFLDGCFILQFLICFMQKPENLKISSHDAVLVTKDLFLLENQLPFSVLKSLMSFRYKKSDQGGGEGMKLFADFFKHIRAIPPRRESCRDKISNFFCKLVPKSLS---SLSGLSGDQHEPAHLLEFFHMQFVGRQIN---LSDHTSQTSWQEDDTRTIWYRYYPAEELRDIGIHFKPSKTSHFTDVQFKPTWLAGRLYIPPLSIDDSTKSLLLNLVAYEATLDTSKDW-ITSYVCFMDSLIDHPEDVKELRSQGILLTTLGSDKQVAELFNEIANNIVPNP 412          

Query:  103 IQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAA---------------------GAS-AKPFRW--YKRMMRQDLKFELRLGVCMEDSWPT----THLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRC-SEGMLLRDISFKSLCFAGFLFLPAMNADAM--PLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHI-SSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYS 1308
            IQ V   L+ +KN +KY+EPRV AIGP HHGK  + + E++K  LAA+FV DSG++E  L K+VE+NIK LK+CYDE+ T++YD D  SLAWM FVDGCS L+FI KY  LE F+IKRDQV FAEQD+FLLENQ+PY++L LLMSSS K+E+L   I+ F+ MH  A                      GA  A+P +      + R++ +    + + ++   PT    THLLELL TRMLG A    E + N    SFRN +EL AAGIHFR   EG LL DI FKS    GFL+LP +  D    P F+NLIAYEMCPDFQND+ VTSY+SFL S I HP+D K LR   IL N L +DE +AQLFNEIG DLV N +I  I  S++E HY++ WK W+AQFF +HFSSPW +LAFIG L  L ++A QTWY+
Sbjct:   65 IQRVPFMLQDHKNFQKYYEPRVAAIGPFHHGKPKYEQAEKVKRHLAANFVKDSGQNEADLLKKVEENIKRLKECYDEEATKKYDDD--SLAWMLFVDGCSTLEFIYKYEKLESFKIKRDQVAFAEQDMFLLENQLPYQLLKLLMSSSSKHEELKESIERFVQMHGVAPPDENQKSQQDARKPEQKPPQPGAGLARPGQHPAVTNINREENQHSQSIAITIKPK-PTEPEPTHLLELLLTRMLGYAPRKSEPSVNLGAQSFRNVQELQAAGIHFRPRKEGSLLGDIDFKSYICCGFLYLPKIKVDDSMGPKFMNLIAYEMCPDFQNDFGVTSYISFLDSLIDHPDDVKHLRKKHILRNLLGSDEEVAQLFNEIGTDLVPNNAIYRIVKSKIEDHYQTMWKKWVAQFFHEHFSSPWTILAFIGVLLGLGMTAAQTWYA 497          

Query:  127 RSNKNLEKYFEPRVLAIGPIHHGKFPEW----EELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEG-MLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSII-HISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTW 1302
            R +   ++Y+EPRV AIGP HH KF +W    E+LK +LA +FV DS ++E  L K+V+ NIKEL++CY ++ T RY  D+  LA M FVDGCS L+FI KY  LE FEIK DQV  AEQD+FLLENQ+PY++L LLMSSS  +EDL   I+ F+ MHST   A  +P R      R+D++        +      THLLELLRTR+LG      E + N  P SF N +EL AAGI FR   G  +L DI FKS  + GFL+LP +  D      F+NLIAYEMCPDFQND+ VTSY+ FL S I + +D K LR   IL N L +DE +A+LFNEIG DLV N +I  ++   +E HY+++WK WMAQFF DHFS PW +LAFIG L+ L LSA+QTW
Sbjct:    3 REDHKYQRYYEPRVTAIGPFHHDKF-QWCQQGEKLKLQLAVNFVRDSKQNEADLLKKVDVNIKELRECYAQEPTGRYVDDD--LALMLFVDGCSTLEFIYKYDDLECFEIKSDQVALAEQDIFLLENQLPYQLLKLLMSSSSIHEDLEDSIERFVLMHSTF--APYQPQRVAGAARREDVR--------ISTEPEPTHLLELLRTRILGYPPKKSEPSVNIRPQSFHNVQELQAAGIQFRPVRGPSVLGDIYFKSFLWLGFLYLPKIKVDDSMAHKFMNLIAYEMCPDFQNDFGVTSYIGFLDSLINYADDVKHLRKNHILRNLLGSDEEVARLFNEIGTDLVPNNAIYRNVKRMIEDHYQTRWKKWMAQFFYDHFSKPW-ILAFIGVLSGLGLSAVQTW 388          

Query:    4 ADSLEQRFNRLRDAGTKNQDXXXXXXXXXXXXIIQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWE---ELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSL-CFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSII-HISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPK 1332
            A   E+R N+LR+     Q              IQ V   LR +K  +KY+EP V A+GP HH + P++E   ++K +LAA+FV DS +++  L K+VEDNI EL++CYDE+ T++YD +   LAWM FVDGCS L+FI KY  LE F+IKRDQV F E D+FLLENQ+PY++L LLMSSS  +++L   I  F+  +S AA  +        +  +     E R     E     THLLELLRT M              LP      +EL A+GIHF+ SEG  LR I F S   F G L LP +  D    P F+NLIAYEMCPDF ND+ VTSY+ FL S I  P+D K LR  +IL N L  DE +AQLFNEIG DLV N  I   +  ++E HY +     MAQFF +HFSSPW  +AF+GAL AL  S +QT YS++ YH  K
Sbjct:   40 ASPREERLNKLREEAPPIQAEKVKPK-------IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDE--FLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFLLENQLPYQLLQLLMSSSQIHKELKKSIDEFVGRNSPAAAPA-------DQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTM--------------LPYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFLGALLALGSSIVQTVYSVLGYHSSK 459          

Query:    4 ADSLEQRFNRLRDAGTKNQDXXXXXXXXXXXXIIQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWE---ELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGAS---AKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIH-ISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPK 1332
            A + E+R N+LR+     Q              IQ V   LR +   +KY+EP V A+GP HH + P++E   ++K +LAA+FV DS +++  L K+VEDNI EL++CYDE+ T+ Y+ +   LAWM FVDGCS L+FI KY  LE F+IKRDQ            NQ+PY++L LLMSSS  ++ L   I  F+  +S A       AKP                            THLLELLRT MLG + +  +    +LP SFRN +EL AAGIHFR S    LR ISF S    G L+LP +  D    P F+NLIAYEMCPDF ND+ VTSY+ FL S I HP+D K LR   IL N L  DE +AQLFNEIG DLV N  I + +  ++EKHY +     MAQFF +HFSSPW ++AF+GAL AL  S +QT YS++ YH  K
Sbjct:   40 ASTREERLNKLREEAPPIQAEKVKPK-------IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDE--FLAWMLFVDGCSTLEFIYKYDELENFQIKRDQ------------NQLPYQLLQLLMSSSQIHKKLKKSIDDFVWRNSLAQNQQNPEAKP----------------------------THLLELLRTTMLGTSPS-EKTKGTKLPHSFRNVQELQAAGIHFRPSNSNSLRSISFISSLCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFLGALLALGSSIVQTVYSVLGYHNNK 441          

Query:    1 MADSLEQRFNRLRDAGTK---NQDXXXXXXXXXXXXIIQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKN-GREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLV 1134
            M DS+EQ  ++LRDA  +                   IQ+V R LRS+ NL K FEPRVLA+G IHHG+  E EELKY LAADF+ D G +   LY+ ++ NI ++K CYD +TT+ YD DEA LAWM F+DGCS LQFI KY  LE+F +K  QV FA  DLFLLENQ+PY +L LL  SS K ++L   ++ F                  K   R +LK+             +THLL+ LR  MLGP++         +  PSFRN +EL AAG+HFR                   FL LP +N DAM  FLNLIAYEMCPDF+ND+AVTSY  FLSS I HPEDAKQLRSARIL N   +DEALA  F+EIGPDLV
Sbjct:   14 MLDSVEQGVDKLRDAERRLPTPDGNDNSATSNSSKSKIQSVPRILRSHSNLVKCFEPRVLAMGQIHHGECKEAEELKYTLAADFIKDCGCTYNHLYETIQKNILKIKDCYDSETTKCYDDDEA-LAWMLFIDGCSTLQFIHKYDCLEDFGMKATQVAFARLDLFLLENQLPYRVLKLLKRSSRKEDELNRNMKRFAKCRLLQQ----------KSQRRGELKY-------------STHLLDFLRKEMLGPSEELSYRGGKEDCSPSFRNVQELKAAGVHFR------------------RFLSLPPINEDAMSSFLNLIAYEMCPDFRNDFAVTSYFGFLSSLIAHPEDAKQLRSARILSNLRGSDEALADFFHEIGPDLV 353          

Query:  703 THLLELLRTRMLGPAKN--GREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAM--PLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSI-IHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            THLL+LLR R+LGP K    ++        +FRN +EL AAGIHF+ S+   L DISFKS CFAGFL LP ++ D    P F+NLIAYEMCPDFQNDY V SY+ FL + I H +D K+LRSA +L N L +D+ +AQLFNEIG DLV N +I + + + LEKHYK+KWK WM+QF  DHFSSPW +LAF+G L+AL LS IQTWY++ S   P
Sbjct:  285 THLLDLLRKRILGPPKKDVSKKKVGESPKQTFRNVQELSAAGIHFQPSKTNFLGDISFKSHCFAGFLSLPPISVDDSTGPKFMNLIAYEMCPDFQNDYGVASYIGFLDALIDHADDVKKLRSASVLFNFLGSDKEVAQLFNEIGTDLVPNTAIYLRVKAELEKHYKTKWKTWMSQFCHDHFSSPWTILAFLGVLSALGLSGIQTWYTVPSQPSP 498          

Query:   16 EQRFNRLRDAGTKNQDXXXXXXXXXXXXIIQNVSRTLRSNKNLEKYFEPRVLAIGPIHHG--KFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTL---EEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMH 588
            E+RF +LRDA                   IQ V   LR +KN +KY+ PR +AIGP HHG  +    ++ K  L   F +  G+ +E LYK++E+ IKEL++CY ++ TE  D  + +LAWM F+DGCS LQFI  YS +   EEFEIKRDQV FA+QDLFLLENQIPY++L LLMSSS K E L H I+ F+ MH
Sbjct:   10 EKRFKKLRDAPKS--------PIPSSQPKIQKVPFMLRDHKNFDKYYVPRAVAIGPFHHGNPRCKLAQKYKLMLTLKFADFVGQKDEDLYKKIEEKIKELRECYVKEATEHID--DGTLAWMLFLDGCSTLQFI--YSLMNEHEEFEIKRDQVAFAQQDLFLLENQIPYQVLELLMSSSDKREVLKHAIESFVQMH 193          

Query:  373 MFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREA--ADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNADAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIHI 1158
            + F+DGCS LQFI K   LEE+ +KRDQ  FAEQDLFL ENQ+PY+ L     S+++   LW               A+ +P   YKR  +Q     + +G   E+  P  HL +LLR R+LGPA    E   +  +  P + NA+EL AA  HF   +G               FL LP +N DAM LFLNLIAYEMCPDF ND+ VT +  F SS + HP+DAKQL+SARI  N   +DEALA LF+EIGPDL S  SI +I
Sbjct:   81 ILFIDGCSTLQFIYKRHCLEEYGMKRDQEAFAEQDLFLPENQLPYQEL-----SAMERFALWQ------------ITAAEEPPDEYKRGFQQREGRPINMG---EEPQPA-HLPDLLRKRLLGPALTHMEKWISTEDRFPLYHNAQELKAARTHFGRGKG---------------FLSLPPINEDAMSLFLNLIAYEMCPDFLNDFVVTFFFGFPSSVVAHPDDAKQLQSARIFCNLRGSDEALADLFHEIGPDLASTHSIHNI 308          

Query:  145 EKYFEPRVLAIGPIHHGKFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVF----------FAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGP---AKNGR--EAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNP--SIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYP 1329
            +K ++P+V   GP H       E  K+R    F+   G+  E     + + +++LK  YD+      D D A    +  +DGC +L+ ++  S + +     D VF          + ++D+ ++ENQ+P  +LN L+     N+D     +  L  + +   AS                    +G C+       H+L++ R  +L      K GR   A  N       +A EL  AGI F+ S+   L+DISF      G L LP +  D     +FLNLIA+E       +  VTSY+ F+ + I +  D   L S  I+ N L +D+A+A LFN +  D+  +P  S+  +  ++  + +  W  W A     +F +PWA+++ I  +    L+  QT YSII Y+YP
Sbjct:   41 KKAYKPQVATFGPYHFDHLNTTEVHKHRALLHFLKRCGKPFELFVNALTEVVQDLKDSYDQLDPGWKD-DTARFLQLMILDGCFMLEVVRIASNILDDYALNDPVFSNHGKLHIIPYIKRDMLMIENQLPMLVLNKLVEVE-SNKDELSVTRLLLKFYYSGTSAS-------------------NMGKCL-------HVLDVYRKSLLQSEPQCKTGRCPPAPVNRHDVIIWSATELNEAGIRFKKSKTGSLKDISFSG----GILRLPVIIVDDTTESMFLNLIAFERFHVGAGN-EVTSYIFFMDNIIDNARDVALLHSKGIVQNALGSDKAVANLFNSLSKDITLDPESSLDAVHKKVYHYCRKPWNEWRANLIHTYFRNPWAVISLIAGVFLFVLTIAQTGYSIIPYYYP 421          

Query:  154 FEPRVLAIGPIHHG---KFPEWEELK-YRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVF-------FAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKN-----------GREAADNE--LPPSFRNAKELMAAGIHFRCSEG----MLLRDISFKSLCFAGFLFLPAMNADAM--PLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDL-VSNPSIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 1311
            +EP +++IGP H G   KF   E++K + L     + +  S + L K + +  +  + CY +        D      M  +DGC +L+  +K    +  + + D VF       +   DL LLENQ+P+ +L  L + +  N               T+A  +     ++K+ +  D   +L L +  E      H+L+L+RT  + P KN            +E   NE   P    NA  L  AG+ FR S+     ++  +  FK+    G   +P +  D    PLF NLIA+E C      + +TSY   + + I   +D + LR   IL N L  ++A AQ FNE+  D  V       + + + K+Y + W  WM +   D+FS+PWA+++FI A   L L+ +QT Y+I
Sbjct:   62 YEPDIVSIGPFHRGCGEKFQLMEKVKRWYLQCLLSSRTDISLDSLIKGIMELGRRARDCYADPLEHLSQKD---FVQMMILDGCFLLELFRK-ELWDYLQDENDPVFNLSCMLEYLYHDLLLLENQLPWFVLERLYNLTANNTS------------QTSASLTKLVLNFFKQSVFDDQISDLNLNLPFE----ILHILDLIRTVTVVPFKNLESQKKEERVEEQEERKNEPEFPQRIPNATTLSEAGVQFRRSKNTPDCIMNIEFDFKN----GVFTIPPLGIDEKTGPLFRNLIAFEQC-HHSRLHKITSYAVLMDNLIDTNKDVELLRERGILANWLSPEDA-AQFFNELYNDTTVIGFYYRGLCNDVNKYYNTDWNKWMEKLKRDYFSTPWAVISFIAAFILLVLTLVQTAYTI 452          

Query:  145 EKYFEPRVLAIGPIHHGK--FPEWEELKYRLAADFVNDSGRSE---EFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAE-------QDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXF-----LDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRC-SEGMLLRDISFKSLCFAGFLFLPAMNA--DAMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNP-SIIHISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYH 1323
            EK F P +++IGP HHG+      EE+K       ++    SE   E+L + +    ++ + CY EK     D        M  VDGC I++  +KY+ +     K D VF+          DLFLLENQ+P+ +L  L  ++ +N +       F        HST + +S                        + +     HLL ++R  +LG     +    +   P   +  EL+ AG+ F+  + G  + DI+F++    G + +P +N   +A  LF NLIAYE C    +   +TSY   L + I   +D   L    I+   L  ++ +A+ F  +  D +    S   ++  +  +YK +W  W      D+F++PW++L+F  AL  L L+ IQT Y+I++++
Sbjct:   47 EKAFLPNLVSIGPFHHGQRNLQVMEEIKLWYVHCLLDRKPTSETRLEYLIELIRSVEQQCRDCYGEKI----DMSSEKFVEMMVVDGCFIIELFRKYARVVPSN-KDDPVFYTLWMHTALINDLFLLENQLPWRVLECLFHNTRENNEKPTNYSLFQLALNFFRHSTFSQSSH-----------------------LNEEVENKHLLGIIRNSLLGSYTQLQLTFKSYWEP-IPSVSELLQAGVQFKLRNTGDNMLDITFEN----GVMEIPPVNIRENAESLFRNLIAYEQCNPSISISNITSYAVVLDNLIKSSKDVHLLIQRGIITTVLSKED-IARFFTRLYNDTIPGYFSYAELTKNVNAYYKDRWHRWQTILRRDYFNNPWSILSFAAALMILGLTFIQTIYTILTFY 426