ppa001444m, ppa001444m (mRNA) Prunus persica

Query:  148 PSHVYTHPAA--------ILLELC---TSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSE---AFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQE--EGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGK--TLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVM-TALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN----SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            P+ ++T PA+         L++ C    S +    I   +I NG   +    TK++ L+   G   +   A ++FE + ++    ++T++  YA+     +A   F RM   GV P  + F   L+VCG       GK++H+ LI+ GF  + F   A+++MYAKC       K+FD M ER+ V+WN+II+  AQ G    AL L +RMQE  +G +PD  T  TLL   A+  +   G+ IHA+++RA+    + + T L+ MYS+CG +  A+ IFNRM ++ A SWNSMI+GY QN + +EA+ +F++M   G +P   ++   L +C  L D ++G+ +H  + +  +  +  +   L+ MY+KC  +D A K++   + K      WN+++ GYA  G   E+ +HF +M   +++ D  TMV+++                          N+ V+ TALVDMY+KCGA+  AR +FD M+ +++ +WNAMI GY  +G  K A+ L+ EM K  + PN++TFL ++SACSH+GLVEEGL+ F SM+EDY +E   +HY  MVDLLGRAG+L +A +F++KMP+EP ++ +GA+LGACR HK++++G  AA ++FEL+P   G +V+++NIY+ A  W +V  +R+MM+MKG++K PG S +++ +E+  F++GS +HP+++ IY  L  L  + K  GY+PDT+    ++ D++ + +E+ L  HSE+LA++ GL++    +TI + KNLR+CGDCH ATK+IS +TGR II RD +RFHHF+NG CSCGDYW
Sbjct:   58 PTSIHTKPASDVNPLPYSSLIQDCIDSNSFQRGKSIHTQMISNGYNPDAYLMTKILMLYARSGCLDDLCYARKLFEEMPERNLTAWNTMILAYARVDDYMEAWGIFDRMLKIGVCPDNFTFASALRVCGALRSRDGGKQVHSKLIACGFKGDTFVGNALIDMYAKCDDEESCLKVFDEMGERNQVTWNSIISAEAQFGHFNDALVLFLRMQESEDGIQPDQFTFTTLLTLCANQRNDNQGRQIHAHLIRANITKNIIVETELVHMYSECGRLNYAKEIFNRMAERNAYSWNSMIEGYQQNGETQEALRLFKQMQLNGIKPDCFSLSSMLSSCVSLSDSQKGRELHNFIVRNTMEEEGILQVVLVDMYAKCGSMDYAWKVYDQTIKKDRNTALWNSILAGYANKGLKKESFNHFLEMLESDIEYDVLTMVTIV--------------------------NLLVLETALVDMYSKCGAITKARTVFDNMNGKNIVSWNAMISGYSKHGCSKEALILYEEMPKKGMYPNEVTFLAILSACSHTGLVEEGLRIFTSMQEDYNIEAKAEHYTCMVDLLGRAGRLEDAKEFVEKMPIEPEVSTWGALLGACRVHKDMDMGRLAAQRLFELDPQNPGPYVIMSNIYAAAGRWKEVEDIRQMMKMKGVKKDPGVSWIEINSEIQIFHAGSKTHPKTEEIYNNLRHLTLQSKGLGYIPDTSFILQNVKDIKEEEEEEYLLQHSERLALSLGLISLPKKSTIRVFKNLRICGDCHTATKFISKITGRRIIARDTNRFHHFENGKCSCGDYW 832          

Query:  277 LVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGD 2475
            L+S+F  +G   EA+ VF  + ++    ++ L+ GYAK     +A++ + RM   G+RP VY F  +L+ CG   DL RG+E+H H+I  GF +++  + A++ MY KC  I  A  +FDRMP RD +SWN +I+GY +N +    L L   M+E    PD +T+ +++ A    G   +G+ +H YV++  F + V+++ +L+ M+S  G    A ++F++M+ K  VSW +MI GY +N   E+A+E +  M  EG  P  +TI   L ACA LG L++G  +H+  D+  L S V V NSL+ MYSKC+ +D A ++F  +  K ++SW ++ILG   N R  EAL  F QM   ++KP+S T+VSV+ A A +      K IH   +RT    + F+  AL+DMY +CG +  A   F+   E+ V +WN ++ GY   G G  AV+LF++M +  + P++ITF  ++ ACS SG+V +GL+YF SM+  + + P + HY ++VDLLGRAG+L +A++FI+KMP++P   ++GA+L ACR ++NVELGE AA  IFE++    GY++LL N+Y+ +  WD+VA+VRK+M    L   PGCS V++  +VH F +G   HPQ K I   LE   ++++A G     +S  D     K ++   HSE+LAIAFGL+NT PGT I + KNL +C +CHN  K+IS V  R I VRD  +FHHFK+G CSCGD
Sbjct:  135 LLSMFVRFGDLVEAWYVFGKMAERDLFSWNVLVGGYAKAGYFDEALNLYHRMLWVGIRPDVYTFPCVLRTCGGLPDLARGREVHLHVIRYGFESDVDVVNALITMYVKCGDIFSARLVFDRMPRRDRISWNAMISGYFENDVCLEGLRLFFMMREFFVDPDLMTMTSVISACEALGDERLGREVHGYVIKTGFVAEVSVNNSLIQMHSSVGCWDEAEMVFSKMEFKDLVSWTAMISGYEKNGLPEKAVETYTIMEHEGVVPDEITIASVLSACAGLGLLDKGIMLHEFADRTGLTSYVIVANSLIDMYSKCRCIDKALEVFHRIPNKNVISWTSIILGLRLNYRSFEALFFFQQM-ILSLKPNSVTLVSVLSACARIGALSCGKEIHAHALRTGLGFDGFLPNALLDMYVRCGRMEPAWNQFNSC-EKDVASWNILLTGYAQQGKGGLAVELFHKMIESDVNPDEITFTSLLCACSRSGMVTDGLEYFESMEHKFHIAPNLKHYASVVDLLGRAGRLEDAYEFIKKMPIDPDPAIWGALLNACRIYQNVELGELAAQHIFEMDTKSVGYYILLCNLYADSGKWDEVARVRKIMRENRLTVDPGCSWVEVAGQVHAFLTGDDFHPQIKEINAVLEGFYEKMEATGLSMSKDSRRDDIDASKAEIFCGHSERLAIAFGLINTVPGTPIWVTKNLYMCENCHNTVKFISKVVRRGISVRDTEQFHHFKDGVCSCGD 865          

Query:  475 LLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWD 1842
            LL++C        G  +H+++  +     +    A+++M+ +   + EA+ +F +M ERDL SWN ++ GYA+ G    AL L  RM   G +PD  T   +L        L  G+ +H +V+R  FES V++  AL+ MY KCG + +ARL+F+RM ++  +SWN+MI GY +N+   E + +F  M +    P  +T+   + AC  LGD   G+ VH  V +    ++VSV NSL+ M+S     D A  +F  +  K LVSW  MI GY +NG   +A+  +  M+ + + PD  T+ SV+ A A L +  +   +H    RT     + V  +L+DMY+KC  +  A ++F  +  ++V +W ++I G   N     A+  F +M   ++KPN +T + V+SAC+  G +  G +  A +++   G +  + +  A++D+  R G++  AW+
Sbjct:  100 LLRLCEWKRAASEGSRVHSYVSKTVTRLGVRLGNALLSMFVRFGDLVEAWYVFGKMAERDLFSWNVLVGGYAKAGYFDEALNLYHRMLWVGIRPDVYTFPCVLRTCGGLPDLARGREVHLHVIRYGFESDVDVVNALITMYVKCGDIFSARLVFDRMPRRDRISWNAMISGYFENDVCLEGLRLFFMMREFFVDPDLMTMTSVISACEALGDERLGREVHGYVIKTGFVAEVSVNNSLIQMHSSVGCWDEAEMVFSKMEFKDLVSWTAMISGYEKNGLPEKAVETYTIMEHEGVVPDEITIASVLSACAGLGLLDKGIMLHEFADRTGLTSYVIVANSLIDMYSKCRCIDKALEVFHRIPNKNVISWTSIILGLRLNYRSFEALFFFQQMIL-SLKPNSVTLVSVLSACARIGALSCGKEIHAHALRTGLGFDGFLPN--ALLDMYVRCGRMEPAWN 553          

Query:  157 VYTHPAAILLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELS-VTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDG---YGTNGLGKAAVDLFNEMEKGTI 1659
            VYT P   +L  C  + +L    ++   +I+ G  ++      L++++   G    A  VF+ +  +  + ++ ++ GY +N    + +  F  M+   V P +   T ++  C    D R G+E+H ++I +GF   +    +++ M++     +EA  +F +M  +DLVSW  +I+GY +NGL + A+E    M+ EG  PD IT+ ++L A A  G L  G  +H +  R    S V ++ +L+DMYSKC  +  A  +F+R+  K  +SW S+I G   N  + EA+  FQ+M+    +P +VT++  L ACA +G L  GK +H    +  LG D  + N+L+ MY +C R++ A   F N   K + SWN ++ GYAQ G+   A+  F +M   ++ PD  T  S++ A +    VT   ++   +  +     N+    ++VD+  + G +  A +    M  +     W A+++    Y    LG+ A     EM+  ++
Sbjct:  195 VYTFPC--VLRTCGGLPDLARGREVHLHVIRYGFESDVDVVNALITMYVKCGDIFSARLVFDRMPRRDRISWNAMISGYFENDVCLEGLRLFFMMREFFVDPDLMTMTSVISACEALGDERLGREVHGYVIKTGFVAEVSVNNSLIQMHSSVGCWDEAEMVFSKMEFKDLVSWTAMISGYEKNGLPEKAVETYTIMEHEGVVPDEITIASVLSACAGLGLLDKGIMLHEFADRTGLTSYVIVANSLIDMYSKCRCIDKALEVFHRIPNKNVISWTSIILGLRLNYRSFEALFFFQQMI-LSLKPNSVTLVSVLSACARIGALSCGKEIHAHALRTGLGFDGFLPNALLDMYVRCGRMEPAWNQF-NSCEKDVASWNILLTGYAQQGKGGLAVELFHKMIESDVNPDEITFTSLLCACSRSGMVTDGLEYFESMEHKFHIAPNLKHYASVVDLLGRAGRLEDAYEFIKKMPIDPDPAIWGALLNACRIYQNVELGELAAQHIFEMDTKSV 699          

Query:  955 TAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSG 1713
            TA + NS+I       D E+A+     M +        T +  L  C        G  VH  V +      V + N+L+SM+ +   +  A  +F  +  + L SWN ++ GYA+ G   EAL+ + +M    ++PD +T   V+     L    + + +H  VIR  F+ ++ V+ AL+ MY KCG + +AR +FD M  R   +WNAMI GY  N +    + LF  M +  + P+ +T   VISAC   G
Sbjct:   58 TAQNPNSLILELCLKGDLEKALIHLDSMQELQVSVEEETYIALLRLCEWKRAASEGSRVHSYVSKTVTRLGVRLGNALLSMFVRFGDLVEAWYVFGKMAERDLFSWNVLVGGYAKAGYFDEALNLYHRMLWVGIRPDVYTFPCVLRTCGGLPDLARGREVHLHVIRYGFESDVDVVNALITMYVKCGDIFSARLVFDRMPRRDRISWNAMISGYFENDVCLEGLRLFFMMREFFVDPDLMTMTSVISACEALG 310          

Query:  508 RRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            R   +IHA L+ SG   + F +T  VN      +I  A K+FD  PE  +  WN II GY+ +     A+E+  RMQ  G  PD  TL  +L A +    L +GK +H  + R  FES V +   L+ +Y+KCG V  AR++F  +  +  VSW SMI GY QN    EA+ IF +M     +P  + ++  L A  D+ DLE+GK +H  V ++ L  +  ++ SL +MY+KC +V +A   F  +    ++ WN MI GYA+NG  +EA+  F +M S+N++ DS T+ S I A A++     AKW+   + +T +  ++FV TAL+DM+AKCG+V  AR++FD   ++ V  W+AMI GYG +G G+ A+DLF  M++  + PND+TF+ +++AC+HSGLVEEG + F SMK  YG+E    HY  +VDLLGR+G L+EA+DFI  MP+EPG++V+GA+LGAC+ +++V LGE AA+++F L+P   G++V L+N+Y+++ LWD VAKVR +M  KGL K  G SL+++  ++  F  G  SHP+ K I+  LE+L   +K AG++P   S+ HD+  + KE+ L +HSE+LAIA+GL++T PGTT+ I KNLR C +CH+ATK IS +  REI+VRD +RFHHFKNG CSC DYW
Sbjct:   85 RHLNQIHAQLVVSGLVESGFLVTKFVNASWNIGEIGYARKVFDEFPEPSVFLWNAIIRGYSSHNFFGDAIEMYSRMQASGVNPDGFTLPCVLKACSGVPVLEVGKRVHGQIFRLGFESDVFVQNGLVALYAKCGRVEQARIVFEGLDDRNIVSWTSMISGYGQNGLPMEALRIFGQMRQRNVKPDWIALVSVLRAYTDVEDLEQGKSIHGCVVKMGLEFEPDLLISLTAMYAKCGQVMVARSFFDQMEIPNVMMWNAMISGYAKNGYTNEAVGLFQEMISKNIRTDSITVRSAILACAQVGSLDLAKWMGDYINKTEYRNDVFVNTALIDMFAKCGSVDLAREVFDRTLDKDVVVWSAMIVGYGLHGRGQDAIDLFYAMKQAGVCPNDVTFVGLLTACNHSGLVEEGWELFHSMKY-YGIEARHQHYACVVDLLGRSGHLNEAYDFITTMPIEPGVSVWGALLGACKIYRHVTLGEYAAEQLFSLDPFNTGHYVQLSNLYASSRLWDSVAKVRILMREKGLSKDLGYSLIEINGKLQAFRVGDKSHPRFKEIFEELESLERRLKEAGFIPHIESVLHDLNQEEKEETLCNHSERLAIAYGLISTAPGTTLRITKNLRACINCHSATKLISKLVNREIVVRDANRFHHFKNGVCSCRDYW 742          

Query:  181 LLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMI 1587
            LL+     + LNQI   ++ +GL       TK V+   N G    A +VF+   +     ++ +++GY+ ++  GDA+  + RM++ GV P  +    +LK C     L  GK +H  +   GF +++F    +V +YAKC ++ +A  +F+ + +R++VSW ++I+GY QNGL   AL +  +M++   KPD I LV++L A  D   L  GKSIH  V++   E   ++  +L  MY+KCG V  AR  F++M+    + WN+MI GY +N    EA+ +FQ+M+ +  +  ++T+  A+ ACA +G L+  K++   +++ +  +DV V  +L+ M++KC  VD+A ++F   L K +V W+ MI+GY  +GR  +A+  F  M+   + P+  T V ++ A     +  +   +   +     +        +VD+  + G ++ A      M  E  V+ W A++
Sbjct:   77 LLDHSVHKRHLNQIHAQLVVSGLVESGFLVTKFVNASWNIGEIGYARKVFDEFPEPSVFLWNAIIRGYSSHNFFGDAIEMYSRMQASGVNPDGFTLPCVLKACSGVPVLEVGKRVHGQIFRLGFESDVFVQNGLVALYAKCGRVEQARIVFEGLDDRNIVSWTSMISGYGQNGLPMEALRIFGQMRQRNVKPDWIALVSVLRAYTDVEDLEQGKSIHGCVVKMGLEFEPDLLISLTAMYAKCGQVMVARSFFDQMEIPNVMMWNAMISGYAKNGYTNEAVGLFQEMISKNIRTDSITVRSAILACAQVGSLDLAKWMGDYINKTEYRNDVFVNTALIDMFAKCGSVDLAREVFDRTLDKDVVVWSAMIVGYGLHGRGQDAIDLFYAMKQAGVCPNDVTFVGLLTACNHSGLVEEGWELFHSMKYYGIEARHQHYACVVDLLGRSGHLNEAYDFITTMPIEPGVSVWGALL 546          

Query:  331 ETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLG-KTLVSWNTMILGYAQNGRVSEALSHFCQMQ-SQNMKPDSFTMVSVIPALAELSVT-RQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            ET +  L    H L + +++N    +A++ F  ++  G      + + +LKVCG   D   GK++H   I  GF  ++   T++V+MY K   + +  ++FD M  +++VSW +++AGY QNGL + AL+L  +MQ EG KP+  T   +L  +A  G++  G  +H  V+++  +S + +  ++++MYSK   V  A+ +F+ M+ + AVSWNSMI G+V N    EA E+F +M  EG + T       +  CA++ ++   K +H  V +     D+++  +LM  YSKC  +D A K+F  + G + +VSW  +I GY QNGR   A++ FCQM+  + ++P+ FT  SV+ A A  + +  Q K  H   I++ F   + V +ALV MYAK G + +A ++F    +R + +WN+MI GY  +G GK ++ +F EM    ++ + ITF+ VISAC+H+GLV EG +YF  M +DY + P M+HY  MVDL  RAG L +A D I KMP   G T++  +L ACR H NV+LGE AA+K+  L P +   +VLL+NIY+TA  W + AKVRK+M+MK ++K  G S ++++N+  +F +G  SHPQS RIY  LE L   +K AGY PDT  + HDVE + KE +L+ HSE+LAIAFGL+ T PGT I I KNLRVCGDCH   K IS + GR+I+VRD +RFHHFK G+CSCGDYW
Sbjct:   51 ETPQQGLSRNNHLLFE-FSRNDQNKEALNLFLGLRRSGSPTDGSSLSCVLKVCGCLFDRIVGKQVHCQCIKCGFVEDVSVGTSLVDMYMKTESVEDGERVFDEMRVKNVVSWTSLLAGYRQNGLNEQALKLFSQMQLEGIKPNPFTFAAVLGGLAADGAVEKGVQVHTMVIKSGLDSTIFVGNSMVNMYSKSLMVSDAKAVFDSMENRNAVSWNSMIAGFVTNGLDLEAFELFYRMRLEGVKLTQTIFATVIKLCANIKEMSFAKQLHCQVIKNGSDFDLNIKTALMVAYSKCSEIDDAFKLFCMMHGVQNVVSWTAIISGYVQNGRTDRAMNLFCQMRREEGVEPNEFTFSSVLNACAAPTASVEQGKQFHSCSIKSGFSNALCVSSALVTMYAKRGNIESANEVFKRQVDRDLVSWNSMISGYAQHGCGKKSLKIFEEMRSKNLELDGITFIGVISACTHAGLVNEGQRYFDLMVKDYHIVPTMEHYSCMVDLYSRAGMLEKAMDLINKMPFPAGATIWRTLLAACRVHLNVQLGELAAEKLISLQPQDSAAYVLLSNIYATAGNWQERAKVRKLMDMKKVKKEAGYSWIEVKNKTFSFMAGDLSHPQSDRIYLKLEELSIRLKDAGYYPDTKYVLHDVEEEHKEVILSQHSERLAIAFGLIATPPGTPIQIVKNLRVCGDCHTVIKLISKIEGRDIVVRDSNRFHHFKGGSCSCGDYW 770          

Query:  235 IKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMK-QKTAVSWNSMIDGYVQNEDAEEAMEIF-QKMLDEGFQPTNVTIMEALHAC-ADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFV----MTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMI 1587
            IK G   +    T LV ++    S  +  RVF+ +  K  V + +LL GY +N     A+  F +M+ +G++P  + F  +L     +  + +G ++H  +I SG  + +F   ++VNMY+K   +++A  +FD M  R+ VSWN++IAG+  NGL   A EL  RM+ EG K       T++   A+   +   K +H  V++   +  +NI TAL+  YSKC  +  A  +F  M   +  VSW ++I GYVQN   + AM +F Q   +EG +P   T    L+AC A    +E+GK  H    +    + + V ++L++MY+K   ++ A ++FK  + + LVSWN+MI GYAQ+G   ++L  F +M+S+N++ D  T + VI A     +  + +    L+++   D +I       + +VD+Y++ G +  A  L + M      T W  ++
Sbjct:  119 IKCGFVEDVSVGTSLVDMYMKTESVEDGERVFDEMRVKNVVSWTSLLAGYRQNGLNEQALKLFSQMQLEGIKPNPFTFAAVLGGLAADGAVEKGVQVHTMVIKSGLDSTIFVGNSMVNMYSKSLMVSDAKAVFDSMENRNAVSWNSMIAGFVTNGLDLEAFELFYRMRLEGVKLTQTIFATVIKLCANIKEMSFAKQLHCQVIKNGSDFDLNIKTALMVAYSKCSEIDDAFKLFCMMHGVQNVVSWTAIISGYVQNGRTDRAMNLFCQMRREEGVEPNEFTFSSVLNACAAPTASVEQGKQFHSCSIKSGFSNALCVSSALVTMYAKRGNIESANEVFKRQVDRDLVSWNSMISGYAQHGCGKKSLKIFEEMRSKNLELDGITFIGVISACTHAGLVNEGQRYFDLMVK---DYHIVPTMEHYSCMVDLYSRAGMLEKAMDLINKMPFPAGATIWRTLL 574          

Query:  595 AKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMM-DERHVTTWNAMIDGYGTNGLGKAAVDLFNEM--EKGTIKPNDITFLCVISAC-SHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTH----KNVELGERAADKIFELNPV 1971
            +K   ++ + ++FD  P++ L   N ++  +++N   K AL L + ++  G   D  +L  +L         I+GK +H   ++  F   V++ T+L+DMY K  SV     +F+ M+ K  VSW S++ GY QN   E+A+++F +M  EG +P   T    L   A  G +E+G  VH +V +  L S + V NS+++MYSK   V  A  +F ++  +  VSWN+MI G+  NG   EA   F +M+ + +K       +VI   A +     AK +H  VI+   D ++ + TAL+  Y+KC  +  A KLF MM   ++V +W A+I GY  NG    A++LF +M  E+G ++PN+ TF  V++AC + +  VE+G Q F S     G   A+    A+V +  + G +  A + + K  ++  +  + +M+     H    K++++ E    K  EL+ +
Sbjct:   37 SKLSTLSHSQQLFDETPQQGLSRNNHLLFEFSRNDQNKEALNLFLGLRRSGSPTDGSSLSCVLKVCGCLFDRIVGKQVHCQCIKCGFVEDVSVGTSLVDMYMKTESVEDGERVFDEMRVKNVVSWTSLLAGYRQNGLNEQALKLFSQMQLEGIKPNPFTFAAVLGGLAADGAVEKGVQVHTMVIKSGLDSTIFVGNSMVNMYSKSLMVSDAKAVFDSMENRNAVSWNSMIAGFVTNGLDLEAFELFYRMRLEGVKLTQTIFATVIKLCANIKEMSFAKQLHCQVIKNGSDFDLNIKTALMVAYSKCSEIDDAFKLFCMMHGVQNVVSWTAIISGYVQNGRTDRAMNLFCQMRREEG-VEPNEFTFSSVLNACAAPTASVEQGKQ-FHSCSIKSGFSNALCVSSALVTMYAKRGNIESA-NEVFKRQVDRDLVSWNSMISGYAQHGCGKKSLKIFEEMRSKNLELDGI 500          

Query:  217 QIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRM-PERDLVSWNTIIAGYAQNGLAKIALELVIRM-QEEGQKPDSITLVTLLPA-VADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERG-KFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNL---LGKTLVSWNTMI 1284
            Q+  ++IK+GL +       +V+++      S+A  VF+++E++  V +++++ G+  N    +A   F RM+ +GV+     F  ++K+C +  ++   K++H  +I +G   +L   TA++  Y+KC +I++A+K+F  M   +++VSW  II+GY QNG    A+ L  +M +EEG +P+  T  ++L A  A   S+  GK  H+  +++ F + + +S+AL+ MY+K G++ +A  +F R   +  VSWNSMI GY Q+   +++++IF++M  +  +   +T +  + AC   G +  G ++   +V    +   +   + ++ +YS+   ++ A  +   +    G T+  W T++
Sbjct:  214 QVHTMVIKSGLDSTIFVGNSMVNMYSKSLMVSDAKAVFDSMENRNAVSWNSMIAGFVTNGLDLEAFELFYRMRLEGVKLTQTIFATVIKLCANIKEMSFAKQLHCQVIKNGSDFDLNIKTALMVAYSKCSEIDDAFKLFCMMHGVQNVVSWTAIISGYVQNGRTDRAMNLFCQMRREEGVEPNEFTFSSVLNACAAPTASVEQGKQFHSCSIKSGFSNALCVSSALVTMYAKRGNIESANEVFKRQVDRDLVSWNSMISGYAQHGCGKKSLKIFEEMRSKNLELDGITFIGVISACTHAGLVNEGQRYFDLMVKDYHIVPTMEHYSCMVDLYSRAGMLEKAMDLINKMPFPAGATI--WRTLL 574          

Query:  193 CTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQ----------------------------NGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            C ++ ++ Q+      +G+    +   KL+  +  Y +  +A+ +F+ +  +  V +  ++ G+AK     +    F  +   G RP  Y   ++++ C D  +L+                      A+V+MY KCR+I +A  +FD+M ERDLV+W  +I GYA+ G A  +L L  +M+EEG  PD + +VT++ A A  G++   + I  Y+ R  F+  V + TA++DMY+KCG V +AR IF+RM++K  +SW++MI  Y  +    +A+++F+ ML  G  P  +T+   L+AC +  +L + + VH       +  ++ V N L+  YS  + +D A  +F  +  +  VSW+ M+ G+A+                             G  +E+L  F +M+ + + PD   MV+V+ A A+L    +A+ I   + R  F  ++ + TA++DM+AKCG V +AR++FD M+E++V +W+AMI  YG +G G+ A+DLF  M +  I PN IT + ++ ACSH+GLVEEGL++F+ M EDY +   + HY  +VDLLGRAG+L EA   I+ M +E    ++GA LGACRTHK+V L E+AA  + EL P   G+++LL+NIY+ A  W+ VAK R +M  + L+K PG + +++ N+ H F  G T+HP+SK IY  L++LG++++  GYVPDTN + HDV+ ++K  +L SHSEKLAIAFGL+ T   T I I KNLRVCGDCH   K +S +TGR IIVRD +RFHHFK G CSCGDYW
Sbjct:   91 CRNLTQVRQVHAQASVHGMLENIVVANKLIYFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYINCFGTFRELIRCGARPDNYTLPFVIRACRDLKNLQM---------------------ALVDMYVKCREIEDARFLFDKMQERDLVTWTVMIGGYAECGKANESLVLFEKMREEGVVPDKVAMVTVVFACAKLGAMHKARIIDDYIQRKKFQLDVILGTAMIDMYAKCGCVESAREIFDRMEEKNVISWSAMIAAYGYHGQGRKALDLFRMMLSSGMLPDKITLASLLYACINCRNLTQVRQVHAQASVHGMLQNLIVANKLVHFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYMNCFGTFRELIRCGARPDNYTLPFCGNANESLVLFDKMREEGVVPDKVAMVTVVFACAKLGAMHKARTIDDYIQRKKFQLDVILGTAMIDMHAKCGCVESAREIFDRMEEKNVISWSAMIAAYGYHGQGRKALDLFPMMLRSGILPNKITLVSLLYACSHAGLVEEGLRFFSLMWEDYSVRADVKHYTCVVDLLGRAGRLDEALKLIESMTVEKDEGLWGAFLGACRTHKDVVLAEKAATSLLELQPQNPGHYILLSNIYANAGRWEDVAKTRDLMSQRRLKKIPGWTWIEVDNKSHQFSVGDTTHPRSKEIYEMLKSLGNKLELVGYVPDTNFVLHDVDEELKIGILYSHSEKLAIAFGLIATPEHTPIRIIKNLRVCGDCHTFCKLVSAITGRVIIVRDANRFHHFKEGACSCGDYW 861          

Query:  781 LPAVADYGSLIIGKSIHAYV-LRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISAC 1701
            + A+ +  +L   + +HA   +    E++V ++  L+  YS   ++  A  +F+ M  + +VSW+ M+ G+ +  D       F++++  G +P N T+   + AC DL +L+                      +L+ MY KC+ ++ A  +F  +  + LV+W  MI GYA+ G+ +E+L  F +M+ + + PD   MV+V+ A A+L    +A+ I   + R  F  ++ + TA++DMYAKCG V +AR++FD M+E++V +W+AMI  YG +G G+ A+DLF  M    + P+ IT   ++ AC
Sbjct:   85 ISALVNCRNLTQVRQVHAQASVHGMLENIV-VANKLIYFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYINCFGTFRELIRCGARPDNYTLPFVIRACRDLKNLQM---------------------ALVDMYVKCREIEDARFLFDKMQERDLVTWTVMIGGYAECGKANESLVLFEKMREEGVVPDKVAMVTVVFACAKLGAMHKARIIDDYIQRKKFQLDVILGTAMIDMYAKCGCVESAREIFDRMEEKNVISWSAMIAAYGYHGQGRKALDLFRMMLSSGMLPDKITLASLLYAC 370          

Query:  991 VQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSG------LVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAAD 1947
            + N + E +   F + L+  F       + AL  C +L  + +   VH       +  ++ V N L+  YS  + +D A  +F  +  +  VSW+ M+ G+A+ G        F ++     +PD++T+  VI A  +L                   KN+    ALVDMY KC  +  AR LFD M ER + TW  MI GY   G    ++ LF +M +  + P+ +  + V+ AC+  G      ++++ +Q     ++ + L+  +    AM+D+  + G +  A +   +M  E  +  + AM+ A   H     G +A D
Sbjct:   63 LHNREEESSKFHFLQRLNPKFY------ISALVNCRNLTQVRQ---VHAQASVHGMLENIVVANKLIYFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYINCFGTFRELIRCGARPDNYTLPFVIRACRDL-------------------KNL--QMALVDMYVKCREIEDARFLFDKMQERDLVTWTVMIGGYAECGKANESLVLFEKMREEGVVPDKVAMVTVVFACAKLGAMHKARIIDDYIQ-----RKKFQLDVILG--TAMIDMYAKCGCVESAREIFDRME-EKNVISWSAMIAAYGYHGQ---GRKALD 346          

Query:  115 AFHTLSQRT--HIPSHVYTHPAAILLELCTSIK--ELNQIIPL-IIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLE-VFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFA-TNLFAMTAVVNMYAK-CRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKC---GSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAE-EAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            AF TL   T  + P  + T+  +ILL+ C   +  +L +++   ++++GL  + +    L+SL+   G    A  +FE + +K + V +  ++  +A NS    A+  F  M   G  P  Y F  +++ C +      G+ I+  ++ +G+   ++     +++M+ K    +  AYK+FD+MPER+LV+W  +I  +AQ G A+ A++L + M+  G  PD  T  ++L A  + G L +GK +H+ V+R      V +  +L+DMY+KC   GSV  +R +F +M +   +SW ++I  YVQ+ + + EA+E+F KM+    +P + +    L AC +L D   G+ V+    +L + S   V NSL+SMY++  R++ A K F  L  K LVS+N ++ GYA+N +  EA   F ++    +   +FT  S++   A +    + + IHG +++  +  N  +  AL+ MY++CG +  A ++F+ M++R+V +W +MI G+  +G    A+++F++M +   KPN+IT++ V+SACSH G++ EG ++F SM +++G+ P M+HY  MVDLLGR+G L EA +FI  MP+     V+  +LGACR H N ELG  AA+ I E  P +   ++LL+N++++A  W  V K+RK M+ + L K  GCS +++ N VH F+ G TSHPQ+ +IY  L+ L  +IK  GY+PDT+ + HD+E + KEQ L  HSEK+A+AFGL++T+    I I KNLRVCGDCH A KYIS+ TGREI+VRD +RFHH KNG CSC DYW
Sbjct:   28 AFSTLDLMTQQNAPPDLTTY--SILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSACSHVGMISEGQKHFNSMYKEHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSNLHASAGQWKDVVKIRKSMKERNLIKEAGCSWIEVENRVHRFHVGETSHPQAWQIYQELDQLASKIKEMGYIPDTDFVLHDIEEEQKEQFLFQHSEKIAVAFGLISTSQSKPIRIFKNLRVCGDCHTAIKYISMATGREIVVRDSNRFHHIKNGVCSCNDYW 827          

Query:  400 LGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRM-PERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASF-ESLVNISTALLDMYSK-CGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCK---RVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRV-SEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKM 1857
            L  A S    M      P +  ++ LLK C    + + GK +H  L+ SG   +   +  ++++Y+KC     A  +F+ M  +RDLVSW+ +++ +A N +   A+   + M E G  P+      ++ A ++     +G+ I+ +V++  + E+ V +   L+DM+ K  G +G+A  +F++M ++  V+W  MI  + Q   A +A+++F  M   G+ P   T    L AC +LG L  GK +H  V +L L  DV V  SL+ MY+KC     VD + K+F+ +    ++SW  +I  Y Q+G    EA+  FC+M S +++P+ F+  SV+ A   LS     + ++   ++        V  +L+ MYA+ G +  ARK FD++ E+++ ++NA++DGY  N   + A  LFNE+    I  +  TF  ++S  +  G + +G Q    + +  G +       A++ +  R G +  A+    +M
Sbjct:   25 LHHAFSTLDLMTQQNAPPDLTTYSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKG-GYKSNQCICNALISMYSRCGNIEAAFQVFNEM 516          

Query: 1303 GRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFD-MMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGR-AGQLSEAWDFIQKMP 1860
            GR+  A S    M  QN  PD  T   ++ +       +  K +H  ++++  + +  V+  L+ +Y+KCG   TAR +F+ M ++R + +W+AM+  +  N +   A+  F +M +    PN+  F  VI ACS++     G   +  + +   LE  +     ++D+  + +G L  A+    KMP
Sbjct:   23 GRLHHAFSTLDLMTQQNAPPDLTTYSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMP 210          

Query:  100 APQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIP 1392
            +P      T S RT+IPSHVY HP+AILLELCTS+KEL+Q IPLIIKNGLY+EHLFQTKLVSLFC +GS  EA RVF+ +EDK++  YHT+LKGYA+NSSL DA+SFFCRM+ DGVRPVVYNFTYLLKVCGDNADLR+GKEIH  LI +GFA+N+FAMT VVNMYAKCR + EAYKMFDRMPERDLV WNTII+GYAQNG  K ALELV+RMQEEG++PDSIT+V++LPAVAD GSL IG+SIH Y +RA FES VN+STAL+DMYSKCGSVGTARLIF+RM                       AMEIFQKM+DE  + TNVT+M ALHACADLGD+E+G+FVHKL+DQL+LGSDVSVMNSL+SMYSKCKR      +F  +  + + +WN MI GY  +G    AL  F +M+ + +KP+  T +   P
Sbjct:   62 SPTSNLHRTPSSRTYIPSHVYKHPSAILLELCTSMKELHQFIPLIIKNGLYSEHLFQTKLVSLFCKFGSLHEAARVFQPIEDKIDELYHTMLKGYARNSSLDDAVSFFCRMRYDGVRPVVYNFTYLLKVCGDNADLRKGKEIHCQLIVNGFASNVFAMTGVVNMYAKCRLVEEAYKMFDRMPERDLVCWNTIISGYAQNGFGKTALELVLRMQEEGKRPDSITIVSILPAVADVGSLRIGRSIHGYSMRAGFESFVNVSTALVDMYSKCGSVGTARLIFDRM----------------------TAMEIFQKMMDEQVEMTNVTVMGALHACADLGDVEQGRFVHKLLDQLELGSDVSVMNSLISMYSKCKR------LFDMMDERHVTTWNAMIDGYGTHGLGKAALELFEKMKKEVIKPNEVTFLCKTP 464          

Query: 1084 LHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGQLSEA---------WDFIQKMPMEP----GITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVL--LANIYSTAS--------------------------------LWDKVAK-VRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            L  C  + +L +  F+  L+ +  L S+      L+S++ K   +  AA++F+ +  K    ++TM+ GYA+N  + +A+S FC+M+   ++P  +    ++    + +  R+ K IH  +I   F  N+F MT +V+MYAKC  V  A K+FD M ER +  WN +I GY  NG GK A++L   M++   +P+ IT + ++ A +  G +  G      SM+   G E  ++   A+VD+  + G +  A          +  QKM  E      +TV GA L AC    +VE G R   K+ +   +     V+  L ++YS                                   L++K+ K V K  E+  L KTPG S+V+L+NEVHTFYSG+TSHPQ+K+IY FLETLG+ IKAAGY+PDTNS+HDVE  VKEQLLNSHSEKLAIAF LLNT+PGTTIH+RKNLRVCGDCHNATKYISLVT REIIVRDM RFHHFK+GTCSCGDYW
Sbjct:   90 LELCTSMKELHQ--FI-PLIIKNGLYSEHLFQTKLVSLFCKFGSLHEAARVFQPIEDKIDELYHTMLKGYARNSSLDDAVSFFCRMRYDGVRPVVYNFTYLLKVCGDNADLRKGKEIHCQLIVNGFASNVFAMTGVVNMYAKCRLVEEAYKMFDRMPERDLVCWNTIISGYAQNGFGKTALELVLRMQEEGKRPDSITIVSILPAVADVGSLRIGRSIHGYSMRA--GFESFVNVSTALVDMYSKCGSVGTARLIFDRMTAMEIFQKMMDEQVEMTNVTVMGA-LHACADLGDVEQG-RFVHKLLDQLELGSDVSVMNSLISMYSKCKRLFDMMDERHVTTWNAMIDGYGTHGLGKAALELFEKMKKEVIKPNEVTFLCKTPGWSVVELQNEVHTFYSGTTSHPQAKKIYAFLETLGNRIKAAGYMPDTNSVHDVEDVVKEQLLNSHSEKLAIAFSLLNTSPGTTIHLRKNLRVCGDCHNATKYISLVTKREIIVRDMRRFHHFKDGTCSCGDYW 597          

Query:  466 FTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLK-LGSDVSVMNSLMSMYSKCKRVDIAAK-------------------------------------------IFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +  +L+ C    +LR G ++HA L+ +G     F  + ++ +Y +   + +A +MFD+M ER++ SW  I+  Y   G  +  ++L   M  EG +PD      +  A ++  +  +GK ++ Y+L   FE    +  ++LDM+ KCG +  AR  F  ++ K    WN M+ GY    + ++A+ +F+KM+ EG +P ++TI  A+ AC +L  L  G+ +H    +++ L SD+ V NSL+  Y+KC+ V++A +                                           +F  L  + +V WN++I   AQ+GR   AL    +M   N++ ++ TMVS +PA ++L+  RQ K IH  +IR   D   F++ +L+DMY +CG++  +R++FD+M +R + +WN MI  YG +G G  AV+LF +     +KPN ITF  ++SACSHSGL+EEG +YF  MK +Y ++PA++ Y  MVDLL RAGQ +E  +FI+KMP EP   V+G++LGACR H N +L E AA  +FEL P   G +VL+ANIYS A  W+  AK+R +M+ +G+ K PGCS ++++ ++H+F  G TSHP  ++I   +E+L  +IK  GYVPDTN +  DV+ D KE  L  HSEK+A+AFGL++TT GT + I KNLRVCGDCH+ATK+IS V  R+II+RD +RFHHF +G CSCGDYW
Sbjct:   13 YASILQKCRKLYNLRLGFQVHAQLVVNGVDVCEFLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVLEGVKPNSITIASAVSACTNLSLLRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIKQTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREMNLSNVEVNTVTMVSALPACSKLAALRQGKEIHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLMPQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMGLKPNHITFTNLLSACSHSGLIEEGWKYFKMMKTEYAMDPAVEQYACMVDLLSRAGQFNETLEFIEKMPFEPNAAVWGSLLGACRIHCNPDLAEYAARYLFELEPQSSGNYVLMANIYSAAGRWEDAAKIRCLMKERGVTKPPGCSWIEVKRKLHSFVVGDTSHPLMEQISAKMESLYFDIKEIGYVPDTNFVLQDVDEDEKEFSLCGHSEKIALAFGLISTTAGTPLRIIKNLRVCGDCHSATKFISKVEKRDIIMRDNYRFHHFVDGVCSCGDYW 729          

Query:  175 AILLELCTSIKELN---QIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRA-SFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSM--IDGYVQNEDAEEAMEIFQKM----------------------------------LD-------EGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRT--CFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMI 1587
            A +L+ C  +  L    Q+   ++ NG+       ++L+ ++C  G   +A R+F+ + ++    +  +++ Y       + +  F  M ++GVRP  + F  + K C +  + R GK+++ +++S GF  N     ++++M+ KC +++ A + F+ +  +D+  WN +++GY   G  K AL +  +M  EG KP+SIT+ + + A  +   L  G+ IH Y ++    +S + +  +L+D Y+KC SV  AR  F  +KQ   VSWN+M  + G+ Q  D + A+E FQ+M                                  LD          +   VT++ AL AC+ L  L +GK +H+ + +  L +   ++NSL+ MY +C  +  + +IF  +  + LVSWN MI  Y  +G   +A++ F Q ++  +KP+  T  +++ A +   +  +  W +  +++T    D  +     +VD+ ++ G  +   +  + M  E +   W +++
Sbjct:   14 ASILQKCRKLYNLRLGFQVHAQLVVNGVDVCEFLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVLEGVKPNSITIASAVSACTNLSLLRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIKQTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREMNLSNVEVNTVTMVSALPACSKLAALRQGKEIHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLMPQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMGLKPNHITFTNLLSACSHSGLIEEG-WKYFKMMKTEYAMDPAVEQYACMVDLLSRAGQFNETLEFIEKMPFEPNAAVWGSLL 533          

Query:  178 ILLELCTSIK--ELNQIIPLIIKNG--LYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKS----DGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPER-----------------------------------DLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDE----------GFQP--------TNVTI-------MEALHACADLGDLER-----GKFVHKLVDQLK-------LGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDS-------FTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            I L+ C  ++  EL ++I    K    + ++    + LV L+   G   EA +VFE  +    V + +++ GY +N+   +A++ F +M      DG  P+V +   L    G        ++I A+L S     ++ + + ++  YA     NEA  +F  M E+                                   D+VSW  +++GYAQNG+A  ++ +   M  +G +PD++ +V +L A ++ G       +H YV+R+ F S V +  +L+++YSKCGS+G A  +F  M  +  V W+SMI  Y  +    EA+EIF +M+              QP        T+ T+       ++A +  A    L         +  +  D  K       L  D  ++     MY    R+D A+ +F+++       WN MI G+A +GR   +L  + +M  + +KPD+        +++SV+ A   L   R+ +W H  VI+T F+ +I V TA++DMY+KCG++  AR LFD    + +  W+AMI  YG +G G+ A+DLF++M K  ++P+ +TF CV+SACSHSGL+EEG  YF  M E++ +   + +Y  MVDLLGRAGQLSEA D I+ MP+EP  +++G++LGACR H N++L E+ AD +F L+PV  GYHVLL+NIY+  S W++V KVRKMM  +G  K  G SLV+  N+VH F  G  SHPQ +++Y  LE L   +K  GYVP T+ + HD+E + KE  L+ HSE+LAIAFGL+NT+PGTT+ I KNLR+CGDCHNA K IS +  R I+VRDMHRFH F++G CSCGDYW
Sbjct:  108 IALKACAGLRMLELGKVIHGFAKKNDEIGSDMFVGSALVELYSKCGQMGEALKVFEEFQRPDTVLWTSMVTGYQQNNDPEEALALFSQMVMMDCFDGDLPLVNSLLNLYAKTGC-------EKIAANLFSKMPEKDVISWSTMIACYANNEAANEALNLFHEMIEKRFEPNSVTVVSALQACAVSRNLEEGKKIHKIAVWKDVVSWVALLSGYAQNGMAYKSMGVFRNMLSDGIQPDAVAVVKILAASSELGIFQQALCLHGYVVRSGFNSNVFVGASLIELYSKCGSLGDAVKLFKGMIVRDVVIWSSMIAAYGIHGRGGEALEIFDQMIQVMQGITSCYQISMQPQVQPPLAITSCTLATHIPWKVKAFYMRAHFRWLGHFWEIFPTYPFQAADMSKSNIFAYGLQYDSRILTKFAIMYVSFNRIDAASIVFEDIPNPCSFLWNVMIRGFATDGRFLSSLELYSKMMEKGLKPDNSGVIPNRVSILSVLLACGNLGALRKGEWFHSYVIQTGFEFDILVATAIMDMYSKCGSLDLARCLFDETAGKDLVCWSAMIASYGIHGHGRKAIDLFDQMVKAGVRPSHVTFTCVLSACSHSGLLEEGKMYFQLMTEEFVIARKLSNYACMVDLLGRAGQLSEAVDLIENMPVEPDASIWGSLLGACRIHNNLDLAEKIADHLFHLDPVHAGYHVLLSNIYAAKSRWNEVEKVRKMMARRGANKIQGFSLVEYDNQVHKFGVGDRSHPQWEKLYAKLEELAAPMKHLGYVPLTDFVLHDIEEEAKEAALSYHSERLAIAFGLINTSPGTTLRITKNLRICGDCHNAIKLISKIVNRVILVRDMHRFHRFEDGVCSCGDYW 956          

Query:  181 LLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSG-FATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEM 1644
            L + C + + ++Q+   + K G+ ++  F TKL SL+    S   A +VF+         +++ L+ Y +     + +  F  M  + G  P  +     LK C     L  GK IH     +    +++F  +A+V +Y+KC Q+ EA K+F+     D V W +++ GY QN   + AL L  +M                                  V+   F+  + +  +LL++Y+K G    A  +F++M +K  +SW++MI  Y  NE A EA+ +F +M+++ F+P +VT++ AL ACA   +LE GK +HK+                                    + K +VSW  ++ GYAQNG   +++  F  M S  ++PD+  +V ++ A +EL + +QA  +HG V+R+ F+ N+FV  +L+++Y+KCG++  A KLF  M  R V  W++MI  YG +G G  A+++F++M
Sbjct:   10 LFQACNNGRSVSQLHSQVFKTGILHDTFFATKLNSLYAKCASLQAARKVFDETPHPNVHLWNSTLRSYCREKQWEETLRLFHLMICTAGEAPDNFTIPIALKACAGLRMLELGKVIHGFAKKNDEIGSDMFVGSALVELYSKCGQMGEALKVFEEFQRPDTVLWTSMVTGYQQNNDPEEALALFSQM----------------------------------VMMDCFDGDLPLVNSLLNLYAKTGCEKIAANLFSKMPEKDVISWSTMIACYANNEAANEALNLFHEMIEKRFEPNSVTVVSALQACAVSRNLEEGKKIHKIA-----------------------------------VWKDVVSWVALLSGYAQNGMAYKSMGVFRNMLSDGIQPDAVAVVKILAASSELGIFQQALCLHGYVVRSGFNSNVFVGASLIELYSKCGSLGDAVKLFKGMIVRDVVIWSSMIAAYGIHGRGGEALEIFDQM 430          

Query:  136 RTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDA-----MSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGS--LIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQP-----TNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            RT I +H       +LL  CT  +        I+ +G   +H     L++++   GS S A +VF+T  ++  V ++ +L  YA +    D      +  F  +++            +LK+C ++  L   + +H + I  G   ++F   A+VN+Y+KC ++ +A  +FD M ERD+V WN ++ GY Q GL K A +L       G +PD  ++  +L      G+  L +GK +H   +++  +S V+++ +L++MYSK G    AR +FN MK    +SWNSMI    Q+   EE++ +F  +L EG +P      ++T+  A  AC  L  L++GK +H    +    SD+ V + ++ MY KC  +  A  +F  +     V+W +MI G   NG   +AL  + +M+   + PD +T  ++I A + ++   Q + +H  VI+     + FV T+LVDMYAKCG +  A +LF  M+ R++  WNAM+ G   +G  + AV+LF  M+   I+P+ ++F+ ++SACSH+GL  E  +Y  SM  DYG+EP ++HY  +VD LGRAG + EA   I+ MP +   ++  A+LGACR   +VE G+R A ++F L P +   +VLL+NIY+ A+ WD V   RKMM+ K ++K PG S +D++N +H F     SHPQ+  IY  +E +   I+  GYVPDT  +  DVE + KE+ L  HSEKLAIA+GL++T   TTI + KNLRVCGDCHNA KYIS V  REI++RD +RFHHF++G CSCGDYW
Sbjct:   85 RTAISTH------NLLLGKCTHAR--------IVVSGSAGDHFLSNNLLTMYSKCGSLSSARQVFDTTPERDLVTWNAILGAYAASVDSNDGNAQEGLHLFRLLRASLGSTTRMTLAPVLKLCLNSGCLWAAEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEFHRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKAGFDSDLHVNSGILDMYIKCGDMVNAGIVFNYISAPDDVAWTSMISGCVDNGNEDQALRIYHRMRQSRVMPDEYTFATLIKASSCVTALEQGRQLHANVIKLDCVSDPFVGTSLVDMYAKCGNIEDAYRLFKKMNVRNIALWNAMLVGLAQHGNAEEAVNLFKSMKSHGIEPDRVSFIGILSACSHAGLTSEAYEYLHSMPNDYGIEPEIEHYSCLVDALGRAGLVQEADKVIETMPFKASASINRALLGACRIQGDVETGKRVAARLFALEPFDSAAYVLLSNIYAAANRWDDVTDARKMMKRKNVKKDPGFSWIDVKNMLHLFVVDDRSHPQADIIYDKVEEMMKTIREDGYVPDTEFVLLDVEDEEKERSLYYHSEKLAIAYGLISTPASTTIRVIKNLRVCGDCHNAIKYISKVFEREIVLRDANRFHHFRDGVCSCGDYW 865          

Query:  475 LLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYA-----QNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHAC--ADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAE-----LSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFAS-MKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVE 1926
            LL+      +L  GK  HA ++ SG A + F    ++ MY+KC  ++ A ++FD  PERDLV+WN I+  YA      +G A+  L L   ++        +TL  +L    + G L   + +H Y ++   E  V +S AL+++YSKCG +  ARL+F+ M+++  V WN M+ GYVQ    +EA ++F +    G +P   ++   L+ C  A   DLE GK VH +  +  L SDVSV NSL++MYSK      A ++F ++    L+SWN+MI   AQ+    E+++ F  +  + +KPD FT+ S+  A A      L +  Q K IH   I+  FD ++ V + ++DMY KCG +  A  +F+ +       W +MI G   NG    A+ +++ M +  + P++ TF  +I A S    +E+G Q  A+ +K D   +P +    ++VD+  + G + +A+   +KM +   I ++ AML     H N E
Sbjct:   83 LLRTAISTHNLLLGKCTHARIVVSGSAGDHFLSNNLLTMYSKCGSLSSARQVFDTTPERDLVTWNAILGAYAASVDSNDGNAQEGLHLFRLLRASLGSTTRMTLAPVLKLCLNSGCLWAAEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEFHRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKAGFDSDLHVNSGILDMYIKCGDMVNAGIVFNYISAPDDVAWTSMISGCVDNGNEDQALRIYHRMRQSRVMPDEYTFATLIKASSCVTALEQGRQLHANVIKLDCVSDPFVG--TSLVDMYAKCGNIEDAYRLFKKMNVR-NIALWNAMLVGLAQHGNAE 576          

Query:  775 TLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNED-----AEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPAL--AELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPN-----DITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKN 1920
            +LL       +L++GK  HA ++ +       +S  LL MYSKCGS+ +AR +F+   ++  V+WN+++  Y  + D     A+E + +F+ +       T +T+   L  C + G L   + VH    ++ L  DV V  +L+++YSKC R+  A  +F  +  + +V WN M+ GY Q G   EA   F +     ++PD F++  ++     A        K +HG+ +++  D ++ V  +LV+MY+K G  + AR++F+ M    + +WN+MI     + L + +V+LF ++    +KP+      IT      AC    L+++G Q  A   +  G +  +     ++D+  + G +  A   +      P    + +M+  C  + N
Sbjct:   82 SLLRTAISTHNLLLGKCTHARIVVSGSAGDHFLSNNLLTMYSKCGSLSSARQVFDTTPERDLVTWNAILGAYAASVDSNDGNAQEGLHLFRLLRASLGSTTRMTLAPVLKLCLNSGCLWAAEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEFHRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIK-AGFDSDLHVNSGILDMYIKCGDMVNA-GIVFNYISAPDDVAWTSMISGCVDNGN 473          

Query:  100 APQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +P      T S RT+IPSHVY HP+AILLELCTS+KEL+Q IPLIIKNGLY+EHLFQTKLVSLFC +GS  EA RVF+ +EDK++  YHT+LKGYA+NSSL DA+SFFCRM+ DGVRPVVYNFTYLLKVCGDNADLR+GKEIH  LI +GFA+N+FAMT VVNMYAKCR + EAYKMFDRMPERDLV WNTII+GYAQNG  K ALELV+RMQEEG++PDSIT+V++LPAVAD GSL IG+SIH Y +RA FES VN+STAL+DMYSKCGSVGTARLIF+RM  KT VSWNSMIDGYVQN D   AMEIFQKM+DE  + TNVT+M ALHACADLGD+E+G+FVHKL+DQL+LGSDVSVMNSL+SMYSKCKRVDIAA+IF+NL  KTLVSWN MILGYAQNGR++EA+ +FC+MQ QN+KPDSFTMVSVIPALAELSV  QAKWIHGLVIRTC DKN+FV TALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGT+GLGKAA++LF +M+K  IKPN++TFLCV+SACSHSGLVEEG QYF SMK+DYGLEPAMDHYGAMVDLLGRA +L+EAWDFIQKMP+EP I+VFGAMLGACR HKNVELGE+AA++IF+L+P +GGYHVLLANIY+TAS+WDKVA+VR  ME KG+QKTPG S+V+L+NEVHTFYSG+TSHPQ+K+IY FLETLG+ IKAAGY+PDTNS+HDVE  VKEQLLNSHSEKLAIAF LLNT+PGTTIH+RKNLRVCGDCHNATKYISLVT REIIVRDM RFHHFK+GTCSCGDYW
Sbjct:   62 SPTSNLHRTPSSRTYIPSHVYKHPSAILLELCTSMKELHQFIPLIIKNGLYSEHLFQTKLVSLFCKFGSLHEAARVFQPIEDKIDELYHTMLKGYARNSSLDDAVSFFCRMRYDGVRPVVYNFTYLLKVCGDNADLRKGKEIHCQLIVNGFASNVFAMTGVVNMYAKCRLVEEAYKMFDRMPERDLVCWNTIISGYAQNGFGKTALELVLRMQEEGKRPDSITIVSILPAVADVGSLRIGRSIHGYSMRAGFESFVNVSTALVDMYSKCGSVGTARLIFDRMTGKTVVSWNSMIDGYVQNGDPGAAMEIFQKMMDEQVEMTNVTVMGALHACADLGDVEQGRFVHKLLDQLELGSDVSVMNSLISMYSKCKRVDIAAEIFENLQHKTLVSWNAMILGYAQNGRINEAIDYFCKMQLQNIKPDSFTMVSVIPALAELSVLPQAKWIHGLVIRTCLDKNVFVATALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTHGLGKAALELFEKMKKEVIKPNEVTFLCVLSACSHSGLVEEGFQYFGSMKKDYGLEPAMDHYGAMVDLLGRANRLNEAWDFIQKMPIEPAISVFGAMLGACRIHKNVELGEKAANRIFDLDPDDGGYHVLLANIYATASMWDKVARVRTTMEKKGIQKTPGWSVVELQNEVHTFYSGTTSHPQAKKIYAFLETLGNRIKAAGYMPDTNSVHDVEDVVKEQLLNSHSEKLAIAFSLLNTSPGTTIHLRKNLRVCGDCHNATKYISLVTKREIIVRDMRRFHHFKDGTCSCGDYW 855          

Query:  211 LNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            L+QI+PLIIKNG YNEHLFQTKL+SLFC + S +EA RVFE VE KL+V YHT+LKGYAKNS+L DA+ F+ RM+ D V PVVY+FTYLL++ G+N DLRRG+EIH  +I++GF +NLFAMTAVVN+YAKCRQI +AYKMF+RMP+RDLVSWNT++AGYAQNG A+ A+++V++MQE GQKPDSITLV++LPAVAD  +L IG+SIH Y  RA FE +VN++TA+LD Y KCGSV +ARL+F  M  +  VSWN+MIDGY QN ++EEA   F KMLDEG +PTNV++M ALHACA+LGDLERG++VH+L+D+ K+G DVSVMNSL+SMYSKCKRVDIAA +F NL  KT+V+WN MILGYAQNG V+EAL+ FC+MQS ++KPDSFT+VSVI ALA+LSVTRQAKWIHGL IRT  DKN+FV TAL+D +AKCGA+ TARKLFD+M ERHV TWNAMIDGYGTNG G+ A+DLFNEM+ G++KPN+ITFL VI+ACSHSGLVEEG+ YF SMKE+YGLEP MDHYGAMVDLLGRAG+L +AW FIQ MP++PGITV GAMLGACR HKNVELGE+ AD++F+L+P +GGYHVLLAN+Y++AS+WDKVA+VR  ME KG+QKTPGCSLV+LRNEVHTFYSGST+HPQSKRIY +LETLGDE+KAAGYVPDTNSIHDVE DVKEQLL+SHSE+LAIAFGLLNT  GT IHIRKNLRVCGDCH ATKYISLVTGREIIVRD+ RFHHFKNG CSCGDYW
Sbjct:    1 LHQILPLIIKNGFYNEHLFQTKLISLFCKFNSITEAARVFEPVEHKLDVLYHTMLKGYAKNSTLRDAVRFYERMRCDEVMPVVYDFTYLLQLSGENLDLRRGREIHGMVITNGFQSNLFAMTAVVNLYAKCRQIEDAYKMFERMPQRDLVSWNTVVAGYAQNGFARRAVQVVLQMQEAGQKPDSITLVSVLPAVADLKALRIGRSIHGYAFRAGFEYMVNVATAMLDTYFKCGSVRSARLVFKGMSSRNVVSWNTMIDGYAQNGESEEAFATFLKMLDEGVEPTNVSMMGALHACANLGDLERGRYVHRLLDEKKIGFDVSVMNSLISMYSKCKRVDIAASVFGNLKHKTVVTWNAMILGYAQNGCVNEALNLFCEMQSHDIKPDSFTLVSVITALADLSVTRQAKWIHGLAIRTLMDKNVFVCTALIDTHAKCGAIQTARKLFDLMQERHVITWNAMIDGYGTNGHGREALDLFNEMQNGSVKPNEITFLSVIAACSHSGLVEEGMYYFESMKENYGLEPTMDHYGAMVDLLGRAGRLDDAWKFIQDMPVKPGITVLGAMLGACRIHKNVELGEKTADELFDLDPDDGGYHVLLANMYASASMWDKVARVRTAMEKKGIQKTPGCSLVELRNEVHTFYSGSTNHPQSKRIYAYLETLGDEMKAAGYVPDTNSIHDVEEDVKEQLLSSHSERLAIAFGLLNTRHGTAIHIRKNLRVCGDCHEATKYISLVTGREIIVRDLRRFHHFKNGICSCGDYW 757          

Query:  370 LLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +LKGYAK+SSL  A+SFF RMK D VRPVVYNFTYLLK+CGDN+DL+RGKEIH  +I+SGF+ NLFAMT VVNMYAKCRQIN+AY MFDRMPERDLV WNT+I+GYAQNG AK+AL LV+RM EEG +PDSIT+V++LPAVAD   L IG ++H YVLRA FESLVN+STAL+DMYSKCGSV  AR+IF+ M  +T VSWNSMIDGYVQ+ DAE AM IFQKMLDEG QPTNVT+M ALHACADLGDLERGKFVHKLVDQLKL SDVSVMNSL+SMYSKCKRVDIAA IFKNL  KTLVSWN MILGYAQNG V+EAL+ FC+MQS+N+KPDSFTMVSVIPALAELS+ RQAKWIHGLVIR   DKN+FVMTALVDMYAKCGA+HTARKLFDMM+ RHV TWNAMIDGYGT+GLGK +V+LF EM+KGTIKPNDITFLC +SACSHSGLVEEGL +F SMK+DYG+EP MDHYGAMVDLLGRAG+L++AWDFIQKMP++PGITV+GAMLGAC+ HKNV+LGE+AA +IF+LNP +GGYHVLLANIY+TAS+W KVAKVR +ME  GLQKTPGCSLV++ NEVH+FYSG+TSHPQSK+IY++LETL DEI+AAGYVPDTNSIHDVE DVK QLLN+HSEKLAIAFGLLNT+ GT IHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFH FK+G CSCGDYW
Sbjct:    1 MLKGYAKSSSLDSALSFFSRMKHDSVRPVVYNFTYLLKLCGDNSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPERDLVCWNTMISGYAQNGFAKVALMLVLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKMLDEGVQPTNVTVMGALHACADLGDLERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEEGLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQKMPIKPGITVYGAMLGACKIHKNVDLGEKAAFEIFKLNPDDGGYHVLLANIYATASMWGKVAKVRTIMEKSGLQKTPGCSLVEIGNEVHSFYSGTTSHPQSKKIYSYLETLVDEIRAAGYVPDTNSIHDVEDDVKVQLLNTHSEKLAIAFGLLNTSTGTPIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHLFKDGVCSCGDYW 704          

Query:  181 LLELC---TSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFV------MTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDG---YGTNGLG-KAAVDLF 1635
            LL+LC   + +K   +I   +I +G        T +V+++      ++A+ +F+ + ++  V ++T++ GYA+N     A+    RM  +G RP       +L    D   LR G  +H +++ +GF + +   TA+V+MY+KC  ++ A  +FD M  R +VSWN++I GY Q+G A+ A+ +  +M +EG +P ++T++  L A AD G L  GK +H  V +   +S V++  +L+ MYSKC  V  A  IF  ++ KT VSWN+MI GY QN    EA+  F +M     +P + T++  + A A+L    + K++H LV +  L  +V VM +L+ MY+KC  +  A K+F  +  + +++WN MI GY  +G    ++  F +M+   +KP+  T +  + A +   +  +     GL       K+  +        A+VD+  + G ++ A      M  +  +T + AM+     +    LG KAA ++F
Sbjct:   36 LLKLCGDNSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPERDLVCWNTMISGYAQNGFAKVALMLVLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKMLDEGVQPTNVTVMGALHACADLGDLERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEE-----GLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQKMPIKPGITVYGAMLGACKIHKNVDLGEKAAFEIF 529          

Query:  121 HTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            H LSQR +IP++VY HPAA+LLE C+S+KEL  I+PLI KNGLY EHLFQTKLVSLFC YGS  EA RVFE ++ KL V Y+T+LKG+AK S L  A+ FF RM+ D V PVVYNFTYLLKVCGD A+LR GKEIH  L+ SGF+ +LFAMT + NMYAKCRQ++EA K+FDRMPERDLVSWNTI+AGY+QNG+A++ALE+V  M EE  KP  IT+V++LPAV+    + IGK IH Y +RA F+SLVNI+TAL+DMY+KCGS+ TARL+F+ M ++  VSWNSMID YVQNE+ +EAM IFQKMLDEG +PT+V++M ALHACADLGDLERG+F+HKL  +L+L  +VSV+NSL+SMY KCK VD AA +F  L  +T+VSWN MILG+AQNGR  EAL++F QMQ++ +KPD+FT VSVI A+AELS+T  AKWIHG+V+R C DKN+FV TALVDMYAKCGA+  AR +FDMM ERHVTTWNAMIDGYGT+G+GKAA++LF EM+KGTI+PN +TFL VISACSHSGLVE GL+ F  MKE+Y +EP+MDHYGAMVDLLGRAG+L+EAWDFI +MP++P + V+GAMLGAC+ HKNV   E+ A+++FELNP +GGYHVLLANIY  AS+W+KV +VR  M  +GL+KTPGCS+V+++NEVH+F+SGST+HP SK+IY FLE L  +IK AGYVPDTN I  +E DVKEQLL+SHSEKLAI+FGLLNTT GTTIH+RKNLRVC DCHNATKYISLVTGREIIVRDM RFHHFKNG CSCGDYW
Sbjct:   23 HFLSQRNYIPANVYEHPAALLLERCSSLKELRHILPLIFKNGLYQEHLFQTKLVSLFCRYGSVDEAARVFEPIDKKLNVLYYTMLKGFAKVSDLDKALKFFVRMRDDEVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVHEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVNLMCEENLKPSFITIVSVLPAVSALRLIRIGKEIHGYAMRAGFDSLVNIATALVDMYAKCGSLKTARLLFDGMLERNVVSWNSMIDAYVQNENPKEAMVIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELELDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTIVSWNAMILGFAQNGRPIEALNYFSQMQARTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRNCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGIGKAALELFEEMQKGTIRPNGVTFLSVISACSHSGLVEAGLKCFHMMKENYSIEPSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKVAERLFELNPEDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPSSKKIYAFLEKLICQIKEAGYVPDTNLILGLEDDVKEQLLSSHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIIVRDMQRFHHFKNGACSCGDYW 809          

Query:  133 QRTHIPSHVYTH--PAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            Q   IP+ VY+H  P+ +LLE CTS KEL QI+P IIKNG YNEHLFQTK++SLFC +GS SEA RVFE VE KL+V YH +LKGYAKNSSLGDA+ FF RM  D VR VV ++  LL++CG+N DL++G+EIH  +I++GF +NLF MTAV+++YAKCRQI+ AYKMF+RM  +DLVSW T++AGYAQNG AK AL+LV++MQE GQKPDS+TL           +L IG+SIH Y  R+ FESLVN++ ALLDMY KCGS   ARL+F  M+ KT VSWN+MIDG  QN ++EEA   F KMLDEG  PT VT+M  L ACA+LGDLERG FVHKL+D+LKL S+VSVMNSL+SMYSKCKRVDIAA IF NL  KT V+WN MILGYAQNG V EAL+ F                 VI ALA+ SV RQAKWIHGL +R C D N+FV TALVDMYAKCGA+ TARKLFDMM ERHV TWNAMIDGYGT+G+GK  +DLFNEM+KG +KPNDITFL VISACSHSG VEEGL  F SM+EDY LEP MDHY AMVDLLGRAGQL +AW+FIQ+MP++PGI+V GAMLGAC+ HKNVELGE+AA K+F+L+P EGGYHVLLANIY++ S+WDKVAKVR  ME KGL KTPGCS V+LRNE+HTFYSGST+HP+SK+IY FLETLGDEIKAAGYVPD +SIHDVE DVK+QLL+SHSE+LAIAFGLLNT+PGTT+HIRKNLRVCGDCH+ TKYISLVTGREIIVRD+ RFHHFKNG+CSCGDYW
Sbjct:   35 QSNSIPTRVYSHRHPSVVLLENCTSKKELYQILPFIIKNGFYNEHLFQTKVISLFCKFGSNSEAARVFEHVELKLDVLYHIMLKGYAKNSSLGDALCFFLRMMCDEVRLVVGDYACLLQLCGENLDLKKGREIHGLIITNGFESNLFVMTAVMSLYAKCRQIDNAYKMFERMQHKDLVSWTTLVAGYAQNGHAKRALQLVLQMQEAGQKPDSVTL-----------ALRIGRSIHGYAFRSGFESLVNVTNALLDMYFKCGSARIARLVFKGMRSKTVVSWNTMIDGCAQNGESEEAFATFLKMLDEGEVPTRVTMMGVLLACANLGDLERGWFVHKLLDKLKLDSNVSVMNSLISMYSKCKRVDIAASIFNNL-EKTNVTWNAMILGYAQNGCVKEALNLF---------------FGVITALADFSVNRQAKWIHGLAVRACMDNNVFVSTALVDMYAKCGAIKTARKLFDMMQERHVITWNAMIDGYGTHGVGKETLDLFNEMQKGAVKPNDITFLSVISACSHSGFVEEGLLLFKSMQEDYYLEPTMDHYSAMVDLLGRAGQLDDAWNFIQEMPIKPGISVLGAMLGACKIHKNVELGEKAAQKLFKLDPDEGGYHVLLANIYASNSMWDKVAKVRTAMEDKGLHKTPGCSWVELRNEIHTFYSGSTNHPESKKIYAFLETLGDEIKAAGYVPDPDSIHDVEEDVKKQLLSSHSERLAIAFGLLNTSPGTTLHIRKNLRVCGDCHDTTKYISLVTGREIIVRDLRRFHHFKNGSCSCGDYW 792          

Query:  361 YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +H  L+  A  S L  A++ F  M S G  PV+  FT LLK+C    DL  G+ +HA L + G  +   A TA+ NMYAKCR+  +A ++FDRMP RD V+WN ++AGYA+NGLA++A+E+V+RMQEE G++PDSITLV++LPA A+  +L   +  HA+ +R+  E LVN++TA+LD Y KCG +  AR++F+ M  K +VSWN+MIDGY QN D+ EA+ +F +M++EG   T+V+++ AL AC +LG L+ G  VH+L+ ++ L S+VSVMN+L++MYSKCKRVD+A+ +F  L  +T VSWN MILG AQNG   +A+  F +MQ +N+KPDSFT+VSVIPALA++S   QA+WIHG  IR   D++++V+TAL+DMYAKCG V+ AR LF+   ERHV TWNAMI GYG++G GKAAV+LF EM+   I PN+ TFL V+SACSH+GLV+EG +YF SMKEDYGLEP M+HYG MVDLLGRAG+L EAW FIQKMPM+PG++V+GAMLGAC+ HKNVEL E +A KIFEL P EG YHVLLANIY+ AS+W  VA+VR  ME  GLQKTPG S++ L+NE+HTFYSGST+H Q+K IY+ L  L +EIKA GYVPDT+SIHDVE DVK QLLN+HSEKLAIAFGL+ T PGTTI I+KNLRVC DCHNATK ISLVTGREII+RD+ RFHHFK+G CSCGDYW
Sbjct:   27 HHARLRAAAARSDLPAALAAFVAMSSAGAPPVLRTFTSLLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQEGVYHVLLANIYANASMWKDVARVRTAMEKNGLQKTPGWSIIQLKNEIHTFYSGSTNHQQAKEIYSRLAKLIEEIKAVGYVPDTDSIHDVEDDVKAQLLNTHSEKLAIAFGLIRTAPGTTIQIKKNLRVCNDCHNATKLISLVTGREIIMRDIQRFHHFKDGKCSCGDYW 734          

Query:  181 LLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAK 1428
            LL+LC +  +L     +   +   G+ +E L  T L +++     P++A RVF+ +  +  V ++ L+ GYA+N     AM    RM + +G RP       +L  C +   L   +E HA  I SG    +   TA+++ Y KC  I  A  +FD MP ++ VSWN +I GYAQNG ++ AL L  RM EEG     ++++  L A  + G L  G  +H  ++R   +S V++  AL+ MYSKC  V  A  +F+ + ++T VSWN+MI G  QN  +E+A+ +F +M  E  +P + T++  + A AD+ D  + +++H    +L L  DV V+ +L+ MY+KC RV+IA  +F +   + +++WN MI GY  +G    A+  F +M+S  + P+  T +SV+ A +   +  + +
Sbjct:   65 LLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGR 484          

Query:  229 LIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLR-ASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVS-WNSMIDGYVQNEDAEEAMEIFQKMLDEGFQ 1056
            L+++ GL +       L++++        A  VF+ ++ + +V ++ ++ G A+N    DA+  F RM+ + V+P  +    ++    D +D  + + IH + I      +++ +TA+++MYAKC ++N A  +F+   ER +++WN +I GY  +G  K A+EL   M+  G  P+  T +++L A +  G +  G+     +      E  +     ++D+  + G +  A     +M     +S + +M+     +++ E A E  QK+ + G Q
Sbjct:  287 LLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQ 564          

Query:  361 YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +H  L+  A  S L  A++ F  M S G  PV+  FT LLK+C    DL  G+ +HA L + G  +   A TA+ NMYAKCR+  +A ++FDRMP RD V+WN ++AGYA+NGLA++A+E+V+RMQEE G++PDSITLV++LPA A+  +L   +  HA+ +R+  E LVN++TA+LD Y KCG +  AR++F+ M  K +VSWN+MIDGY QN D+ EA+ +F +M++EG   T+V+++ AL AC +LG L+ G  VH+L+ ++ L S+VSVMN+L++MYSKCKRVD+A+ +F  L  +T VSWN MILG AQNG   +A+  F +MQ +N+KPDSFT+VSVIPALA++S   QA+WIHG  IR   D++++V+TAL+DMYAKCG V+ AR LF+   ERHV TWNAMI GYG++G GKAAV+LF EM+   I PN+ TFL V+SACSH+GLV+EG +YF SMKEDYGLEP M+HYG MVDLLGRAG+L EAW FIQKMPM+PG++V+GAMLGAC+ HKNVEL E +A KIFEL P EG YHVLLANIY+ AS+W  VA+VR  ME  GLQKTPG S++ L+NE+HTFYSGST+H Q+K IY+ L  L +EIKA GYVPDT+SIHDVE DVK QLLN+HSEKLAIAFGL+ T PGTTI I+KNLRVC DCHNATK ISLVTGREII+RD+ RFHHFK+G CSCGDYW
Sbjct:   27 HHARLRASAARSDLPAALAAFVAMSSAGAPPVLRTFTSLLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQEGVYHVLLANIYANASMWKDVARVRTAMEKNGLQKTPGWSIIQLKNEIHTFYSGSTNHQQAKEIYSRLAKLIEEIKAVGYVPDTDSIHDVEDDVKAQLLNTHSEKLAIAFGLIRTAPGTTIQIKKNLRVCNDCHNATKLISLVTGREIIMRDIQRFHHFKDGKCSCGDYW 734          

Query:  181 LLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAK 1428
            LL+LC +  +L     +   +   G+ +E L  T L +++     P++A RVF+ +  +  V ++ L+ GYA+N     AM    RM + +G RP       +L  C +   L   +E HA  I SG    +   TA+++ Y KC  I  A  +FD MP ++ VSWN +I GYAQNG ++ AL L  RM EEG     ++++  L A  + G L  G  +H  ++R   +S V++  AL+ MYSKC  V  A  +F+ + ++T VSWN+MI G  QN  +E+A+ +F +M  E  +P + T++  + A AD+ D  + +++H    +L L  DV V+ +L+ MY+KC RV+IA  +F +   + +++WN MI GY  +G    A+  F +M+S  + P+  T +SV+ A +   +  + +
Sbjct:   65 LLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGR 484          

Query:  229 LIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLR-ASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVS-WNSMIDGYVQNEDAEEAMEIFQKMLDEGFQ 1056
            L+++ GL +       L++++        A  VF+ ++ + +V ++ ++ G A+N    DA+  F RM+ + V+P  +    ++    D +D  + + IH + I      +++ +TA+++MYAKC ++N A  +F+   ER +++WN +I GY  +G  K A+EL   M+  G  P+  T +++L A +  G +  G+     +      E  +     ++D+  + G +  A     +M     +S + +M+     +++ E A E  QK+ + G Q
Sbjct:  287 LLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQ 564          

Query:  361 YHTLLKGYAKNSSLGDAMSFFCRMK-SDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +H  L+  A  S L  A++ F  M  + G  PV+  FT LLK+C   ADL  G+ +HA L + G +    A TA+ NMYAKCR+  +A ++FDRMP RD V+WN ++AGYA+NGLA+ A+ +V+RMQEE G++PD++TLV++LPA AD  +L   + +HA+ +R  F+  VN+STA+LD+Y KCG+V +AR +F+ M+ + +VSWN+MI GY +N DA EA+ +F++M+ EG   T+V+++ ALHAC +LG L+ G+ VH+L+ ++ L S+V+VMN+L++MY KCKR D+AA++F  L  KT VSWN MILG  QNG   +A+  F +MQ +N+KPDSFT+VS+IPALA++S   QA+WIHG  IR   D++++V+TAL+DMYAKCG V  AR LF+   +RHV TWNAMI GYG++G GK AV+LF EM+     PN+ TFL V+SACSH+GLV+EG +YF+SMKEDYGLEP M+HYG MVDLLGRAG+L EAW FIQKMPMEPGI+V+GAMLGAC+ HKNVEL E +A +IFEL P EG YHVLLANIY+ ASLW  VA+VR  ME KGLQKTPG S+V L+NE+HTFYSGST+H Q+K IY  L  L +EIKA GYVPDT+SIHDVE DVK QLLN+HSEKLAIA+GL+ T PGTTI I+KNLRVC DCHNATK ISLVTGREII+RD+ RFHHFK+G CSCGDYW
Sbjct:   27 HHARLRAAASRSDLRGALAAFAAMSPASGSGPVLRTFTSLLKLCAARADLATGRAVHAQLAARGLSPEALAATALANMYAKCRRPGDARRVFDRMPARDRVAWNALVAGYARNGLAEAAVGMVVRMQEEDGERPDAVTLVSVLPACADAQALGACREVHAFAVRGGFDEQVNVSTAILDVYCKCGAVDSARKVFDGMQDRNSVSWNAMIKGYAENGDATEALALFKRMVGEGVDVTDVSVLAALHACGELGFLDEGRRVHELLVRIGLESNVNVMNALITMYCKCKRTDLAAQVFDELGYKTRVSWNAMILGCTQNGSSEDAVRLFSRMQLENVKPDSFTLVSIIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVSIARSLFNSARDRHVITWNAMIHGYGSHGSGKVAVELFEEMKSSGKVPNETTFLSVLSACSHAGLVDEGQEYFSSMKEDYGLEPGMEHYGTMVDLLGRAGKLHEAWSFIQKMPMEPGISVYGAMLGACKLHKNVELAEESAQRIFELEPEEGVYHVLLANIYANASLWKDVARVRTAMEKKGLQKTPGWSIVQLKNEIHTFYSGSTNHQQAKDIYARLAKLIEEIKAVGYVPDTDSIHDVEDDVKAQLLNTHSEKLAIAYGLIRTAPGTTIQIKKNLRVCKDCHNATKLISLVTGREIIMRDIQRFHHFKDGKCSCGDYW 735          

Query:  181 LLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQA-KWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMI 1587
            LL+LC +  +L     +   +   GL  E L  T L +++     P +A RVF+ +  +  V ++ L+ GYA+N     A+    RM + DG RP       +L  C D   L   +E+HA  +  GF   +   TA++++Y KC  ++ A K+FD M +R+ VSWN +I GYA+NG A  AL L  RM  EG     ++++  L A  + G L  G+ +H  ++R   ES VN+  AL+ MY KC     A  +F+ +  KT VSWN+MI G  QN  +E+A+ +F +M  E  +P + T++  + A AD+ D  + +++H    +L L  DV V+ +L+ MY+KC RV IA  +F +   + +++WN MI GY  +G    A+  F +M+S    P+  T +SV+ A +   +  +  ++   +      +  +     +VD+  + G +H A      M  E  ++ + AM+
Sbjct:   66 LLKLCAARADLATGRAVHAQLAARGLSPEALAATALANMYAKCRRPGDARRVFDRMPARDRVAWNALVAGYARNGLAEAAVGMVVRMQEEDGERPDAVTLVSVLPACADAQALGACREVHAFAVRGGFDEQVNVSTAILDVYCKCGAVDSARKVFDGMQDRNSVSWNAMIKGYAENGDATEALALFKRMVGEGVDVTDVSVLAALHACGELGFLDEGRRVHELLVRIGLESNVNVMNALITMYCKCKRTDLAAQVFDELGYKTRVSWNAMILGCTQNGSSEDAVRLFSRMQLENVKPDSFTLVSIIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVSIARSLFNSARDRHVITWNAMIHGYGSHGSGKVAVELFEEMKSSGKVPNETTFLSVLSACSHAGLVDEGQEYFSSMKEDYGLEPGMEHYGTMVDLLGRAGKLHEAWSFIQKMPMEPGISVYGAML 540          

Query:  370 LLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +LKGYAKNSSLG+A+ FF RM  DGVRPVV ++  LL++CG+N DL+RG+EIH  +I++GF +NLFA+TAV+N+YAKCR+I++AYKMF RMP++DL                  AL+LV +MQ+ GQKPDS+TLV++LPAVAD   L IG+SIH Y  R+ FES VN++ ALLDM+ K G   TARL+F  M  K+ VS N+MIDG  QN+            +DEG  PT VT+M AL ACA+LGDLERG+FVHKL D+LKL S+VSVMNSL+SMYSKCKRVDIAA IF NL  KT  + N MIL YAQNG V EAL+ FC MQSQ +K D FT+V VI ALA+ SV R AKWIHGL IRTC DKN+FV TALVDMYA+CGA+ TARKLFDMM ERHV TWNAM+DGYGT+GLGK A+DLFNEM K  +   ++T++                               + +  AMVDLLG AGQL   W+FIQ MP++PGI+V GAMLGAC+ HKNVELGE+AADK+FEL+P EGGYHVLLANIY++ S WD           KGL KTPGCSLV+LR EVHTFYS ST+HPQSKRIY FLETLGDEIKAAGYVP TNSIHDVE DVKEQLL SHSE+LAIAF L +T+PG T+HIRKNLRVC DCH+ATKYISLV           R+ HFKNG CSCGDYW
Sbjct:    1 MLKGYAKNSSLGEALFFFYRMMCDGVRPVVGDYACLLQLCGENLDLKRGREIHGQIITNGFKSNLFAITAVMNLYAKCREIDDAYKMFKRMPQKDLR-----------------ALQLVFQMQQAGQKPDSVTLVSILPAVADMKPLRIGRSIHGYAFRSGFESPVNVTNALLDMHFKYGHTRTARLVFEGMSSKSVVSRNTMIDGCAQND------------VDEGEVPTRVTMMGALLACANLGDLERGRFVHKLPDKLKLDSNVSVMNSLISMYSKCKRVDIAASIFDNLKEKTNATRNAMILRYAQNGCVKEALNLFCIMQSQGIKLDCFTLVGVITALADFSVNRHAKWIHGLAIRTCMDKNVFVSTALVDMYARCGAIKTARKLFDMMQERHVITWNAMLDGYGTHGLGKEALDLFNEMPKEAL---EVTWV-------------------------------LWNKSAMVDLLGGAGQLDCTWNFIQDMPIKPGISVLGAMLGACKIHKNVELGEKAADKLFELDPNEGGYHVLLANIYASNSTWD-----------KGLHKTPGCSLVELRKEVHTFYSRSTNHPQSKRIYAFLETLGDEIKAAGYVPHTNSIHDVEEDVKEQLLGSHSERLAIAFELWHTSPGMTLHIRKNLRVCVDCHDATKYISLV-----------RYPHFKNGICSCGDYW 619          

Query:  277 LVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACAD-LGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAK 1233
            L+ +   YG    A  VFE +  K  V  +T++ G A+N               +G  P        L  C +  DL RG+ +H         +N+  M ++++MY+KC++++ A  +FD + E+   + N +I  YAQNG  K AL L   MQ +G K D  TLV ++ A+AD+      K IH   +R   +  V +STAL+DMY++CG++ TAR +F+ M+++  ++WN+M+DGY  +   +EA+++F +M  E  + T V   ++  A  D LG   +       +  + +   +SV+ +++      K V++  K
Sbjct:  155 LLDMHFKYGHTRTARLVFEGMSSKSVVSRNTMIDGCAQNDV------------DEGEVPTRVTMMGALLACANLGDLERGRFVHKLPDKLKLDSNVSVMNSLISMYSKCKRVDIAASIFDNLKEKTNATRNAMILRYAQNGCVKEALNLFCIMQSQGIKLDCFTLVGVITALADFSVNRHAKWIHGLAIRTCMDKNVFVSTALVDMYARCGAIKTARKLFDMMQERHVITWNAMLDGYGTHGLGKEALDLFNEMPKEALEVTWVLWNKS--AMVDLLGGAGQLDCTWNFIQDMPIKPGISVLGAMLGACKIHKNVELGEK 460          

Query:  121 HTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSG 1713
            +TL +RT+IP H+Y HP A+LLELCTS+KEL+QIIP IIKNG Y+E LFQTKL+SLFCNYGS +EA RVFE +E+KLE  YHT+LKG+AKNSSL  A+ FFCRMK D VRPVVYNFTYLL +CGDN DLRRGKEIH  LI+SGF+ NLFAMTAVV++Y KCR I +AYKMFDRM ERDLV WNTII+GYAQNGL K+ALELV ++ EEG +PDS+T+V++LPAVAD  SL  GK+IHAYV+RA F+ LVNISTAL+DMYSKC S+GTAR+IF+ M  +T V+WNSMI G V+N D EEA  +F+KM+DEG QPT+VT+ME LHACAD GDLE+GKFVHKLV+ LKL S+VSVMNSL+SMYSKCK+VD AA +F+NL  +TLVSWN MILGYAQNGR++EAL+ FC+MQSQN+KPDSFTMVSVIPALAELS+ RQAKWIHGLVIR   D  +FVMTALVDMYAKCGA+HTARKLF+MM ERHV TWN+MID YGT+GLGK AV LF EM+KGTIKPND+TFLCV+SACSHSG
Sbjct:   30 NTLPRRTYIPGHIYKHPTAVLLELCTSVKELHQIIPSIIKNGFYSEELFQTKLISLFCNYGSLTEAARVFEPIENKLEALYHTMLKGFAKNSSLDSALLFFCRMKHDNVRPVVYNFTYLLTLCGDNFDLRRGKEIHGQLITSGFSWNLFAMTAVVSLYCKCRVIGDAYKMFDRMTERDLVCWNTIISGYAQNGLTKVALELVPKIFEEGHRPDSVTIVSVLPAVADIRSLRFGKAIHAYVIRAGFDWLVNISTALVDMYSKCDSLGTARVIFDGMGSRTVVTWNSMIAGCVENGDPEEAKVLFKKMMDEGLQPTDVTVMEVLHACADSGDLEQGKFVHKLVEDLKLDSNVSVMNSLISMYSKCKQVDFAANLFENLQNRTLVSWNAMILGYAQNGRLNEALNFFCEMQSQNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRLLDDTVFVMTALVDMYAKCGAIHTARKLFNMMSERHVITWNSMIDAYGTHGLGKEAVQLFVEMQKGTIKPNDVTFLCVLSACSHSG 560          

Query:  838 VLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKM 1857
            +++  F S     T L+ ++   GS+  A  +F  ++ K    +++M+ G+ +N   + A+  F +M  +  +P        L  C D  DL RGK +H  +       ++  M +++S+Y KC+ +  A K+F  +  + LV WNT+I GYAQNG    AL    ++  +  +PDS T+VSV+PA+A++   R  K IH  VIR  FD  + + TALVDMY+KC ++ TAR +FD M  R V TWN+MI G   NG  + A  LF +M    ++P D+T + V+ AC+ SG +E+G ++   + ED  L+  +    +++ +  +  Q+  A +  + +
Sbjct:   67 IIKNGFYSEELFQTKLISLFCNYGSLTEAARVFEPIENKLEALYHTMLKGFAKNSSLDSALLFFCRMKHDNVRPVVYNFTYLLTLCGDNFDLRRGKEIHGQLITSGFSWNLFAMTAVVSLYCKCRVIGDAYKMFDRMTERDLVCWNTIISGYAQNGLTKVALELVPKIFEEGHRPDSVTIVSVLPAVADIRSLRFGKAIHAYVIRAGFDWLVNISTALVDMYSKCDSLGTARVIFDGMGSRTVVTWNSMIAGCVENGDPEEAKVLFKKMMDEGLQPTDVTVMEVLHACADSGDLEQG-KFVHKLVEDLKLDSNVSVMNSLISMYSKCKQVDFAANLFENL 405          

Query:    1 MSSQLLHYTALLPITNSIXXXXXXXXXXXXXISAPQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            MSSQL+ ++ +  I N                  P  +  H LS+R +IP++VY HPAA+LLE C+S+KEL QI+PL+ KNGLY EH FQTKLVSLFC YGS  EA RVFE ++ KL V YHT+LKG+AK S L  A+ FF RM+ D V PVVYNFTYLLKVCGD A+LR GKEIH  L+ SGF+ +LFAMT + NMYAKCRQ+NEA K+FDRMPERDLVSWNTI+AGY+QNG+A++ALE+V  M EE  KP  IT+V++LPAV+    + +GK IH Y +R+ F+SLVNISTAL+DMY+KCGS+ TAR +F+ M ++  VSWNSMID YVQNE+ +EAM IFQKMLDEG +PT+V++M ALHACADLGDLERG+F+HKL  +L L  +VSV+NSL+SMY KCK VD AA +F  L  +TLVSWN MILG+AQNGR  +AL++F QM+S+ +KPD+FT VSVI A+AELS+T  AKWIHG+V+R+C DKN+FV TALVDMYAKCGA+  AR +FDMM ERHVTTWNAMIDGYGT+G GKAA++LF EM+KGTIKPN +TFL VISACSHSGLVE GL+ F  MKE+Y +E +MDHYGAMVDLLGRAG+L+EAWDFI +MP++P + V+GAMLGAC+ HKNV   E+AA+++FELNP +GGYHVLLANIY  AS+W+KV +VR  M  +GL+KTPGCS+V+++NEVH+F+SGST+HP SK+IY FLE L   IK AGYVPDTN +  VE DVKEQLL++HSEKLAI+FGLLNTT GTTIH+RKNLRVC DCHNATKYISLVTGREI+VRDM RFHHFKNG CSCGDYW
Sbjct:    1 MSSQLVQFSTVPQIPN------------------PPSRHRHFLSERNYIPANVYEHPAALLLERCSSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSKKIYAFLEKLICHIKEAGYVPDTNLVLGVENDVKEQLLSTHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIVVRDMQRFHHFKNGACSCGDYW 809          

Query:  181 LLELCT---SIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHF-CQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +L+LC    S+K+  ++   I  NG   +    +KL  ++ N G   EA RVF+ V+ +  +F++ L+   AK+     ++  F +M S GV    Y F+ + K       +  G+++H  ++ SGF        ++V  Y K ++++ A K+FD M ERD++SWN+II GY  NGLA+  L + ++M   G + D  T+V++    AD   + +G+++H+  ++A F         LLDMYSKCG + +A+ +F  M  ++ VS+ SMI GY +   A EA+++F++M +EG  P   T+   L+ CA    L+ GK VH+ + +  LG D+ V N+LM MY+KC  +  A  +F  +  K ++SWNT+I GY++N   +EALS F   ++ +   PD  T+  V+PA A LS   + + IHG ++R  +  +  V  +LVDMYAKCGA+  A  LFD +  + + +W  MI GYG +G GK A+ LFN+M +  I+ ++I+F+ ++ ACSHSGLV+EG ++F  M+ +  +EP ++HY  +VD+L R G L +A+ FI+ MP+ P  T++GA+L  CR H +V+L E+ A+K+FEL P   GY+VL+ANIY+ A  W++V ++RK +  +GL+K PGCS ++++  V+ F +G +S+P+++ I  FL  +   +   GY P T  ++ D E   KE+ L  HSEKLA+A G++++  G  I + KNLRVCGDCH   K++S +T REI++RD +RFH FK+G CSC  +W
Sbjct:  100 VLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDRHVANSLVDMYAKCGALLLAHMLFDDIASKDLVSWTVMIAGYGMHGFGKEAIALFNQMRQAGIEADEISFVSLLYACSHSGLVDEGWRFFNIMRHECKIEPTVEHYACIVDMLARTGDLIKAYRFIENMPIPPDATIWGALLCGCRIHHDVKLAEKVAEKVFELEPENTGYYVLMANIYAEAEKWEQVKRLRKRIGQRGLRKNPGCSWIEIKGRVNIFVAGDSSNPETENIEAFLRKVRARMIEEGYSPLTKYALIDAEEMEKEEALCGHSEKLAMALGIISSGHGKIIRVTKNLRVCGDCHEMAKFMSKLTRREIVLRDSNRFHQFKDGHCSCRGFW 871          

Query:  646 ERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKE-DYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGI---TVFGAMLGACRTHKNVEL 1929
            +R +   NT +  + ++G  + A++L+    +    P   TL ++L   AD  SL  GK +  ++    F    N+ + L  MY+ CG +  A  +F+ +K + A+ WN +++   ++ D   ++ +F+KM+  G +  + T      + + L  +  G+ +H  + +   G   SV NSL++ Y K +RVD A K+F  +  + ++SWN++I GY  NG   + LS F QM    ++ D  T+VSV    A+  +    + +H + ++ CF +       L+DMY+KCG + +A+ +F  M +R V ++ +MI GY   GL   AV LF EME+  I P+  T   V++ C+   L++EG +    +KE D G +  + +  A++D+  + G + EA     +M ++  I   T+ G     C  ++ + L
Sbjct:   58 DRSVTDANTQLRRFCESGNLENAVKLLCVSGKWDIDPR--TLCSVLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSN--ALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSL 485          

Query:  280 VSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMK-SDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGY--VPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGD 2475
            +++F  +G+  +A+ VF  + ++    ++ L+ GYAK     +AM  + RM    GV+P VY F  +L+ CG   DL RGKE+H H++  G+  ++  + A++ MY KC  +  A  +FDRMP RD++SWN +I+GY +NG+    LEL   M+     PD +TL +++ A    G   +G+ IHAYV+   F   +++  +L  MY   GS   A  +F+RM++K  VSW +MI GY  N   ++A++ ++ M  +  +P  +T+   L ACA LGDL+ G  +HKL  + +L S V V N+L++MYSKCK +D A  IF N+  K ++SW ++I G   N R  EAL    QM+   ++P++ T+ + + A A +      K IH  V+RT    + F+  AL+DMY +CG ++TA   F+   ++ VT+WN ++ GY   G G   V+LF+ M K  ++P++ITF+ ++  CS S +V +GL YF+ M EDYG+ P + HY  +VDLLGRAG+L EA  FIQKMP+ P   V+GA+L ACR H  ++LGE +A  IFEL+    GY++LL N+Y+    W +VAKVR+MM+  GL    GCS V+++ +VH F S    HPQ+K I T LE   +++   G   + +++S+ + E   ++++   HSE+ AIAFGL+NT PG  I + KNL +C +CH+  K+IS    REI VRD   FHHFK+G CSCGD
Sbjct:  136 LAMFVRFGNLVDAWYVFGKMSERNLFSWNVLVGGYAKQGYFDEAMCLYHRMLWVGGVKPDVYTFPCVLRTCGGIPDLARGKEVHVHVVRYGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRRDIISWNAMISGYFENGMCHEGLELFFAMRGLSVDPDLMTLTSVISACELLGDRRLGRDIHAYVITTGFAVDISVCNSLTQMYLNAGSWREAEKLFSRMERKDIVSWTTMISGYEYNFLPDKAIDTYRMMDQDSVKPDEITVAAVLSACATLGDLDTGVELHKLAIKARLISYVIVANNLINMYSKCKCIDKALDIFHNIPRKNVISWTSIIAGLRLNNRCFEALIFLRQMK-MTLQPNAITLTAALAACARIGALMCGKEIHAHVLRTGVGLDDFLPNALLDMYVRCGRMNTAWSQFN-SQKKDVTSWNILLTGYSERGQGSMVVELFDRMVKSRVRPDEITFISLLCGCSKSQMVRQGLMYFSKM-EDYGVTPNLKHYACVVDLLGRAGELQEAHKFIQKMPVTPDPAVWGALLNACRIHHKIDLGELSAQHIFELDKKSVGYYILLCNLYADCGKWREVAKVRRMMKENGLTVDAGCSWVEVKGKVHAFLSDDKYHPQTKEINTVLEGFYEKMSEVGLTKISESSSMDETEIS-RDEIFCGHSERKAIAFGLINTVPGMPIWVTKNLSMCENCHDTVKFISKTVRREISVRDAEHFHHFKDGECSCGD 866          

Query:  238 KNGLYNEHLFQTKLVSLFCNYG------SPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRM-QEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFAS-MKEDYGLEPAMDHYGAMVDLLGRAGQLSEAW 1839
            K+  +    ++ + V+ + N+G        S+   V  +       F ++ L G   N  L +AM     M+   V      F  L+++C        G ++++  +SS  +  +    A + M+ +   + +A+ +F +M ER+L SWN ++ GYA+ G    A+ L  RM    G KPD  T   +L        L  GK +H +V+R  +E  +++  AL+ MY KCG V +ARL+F+RM ++  +SWN+MI GY +N    E +E+F  M      P  +T+   + AC  LGD   G+ +H  V       D+SV NSL  MY        A K+F  +  K +VSW TMI GY  N    +A+  +  M   ++KPD  T+ +V+ A A L        +H L I+      + V   L++MY+KC  +  A  +F  +  ++V +W ++I G   N     A+    +M K T++PN IT    ++AC+  G +  G +  A  ++   GL+  + +  A++D+  R G+++ AW
Sbjct:   16 KSNSFQSKAYKQRNVNFYWNFGIRRLFLRKSQGLSVLSSSSSSTH-FSNSQLHGLCANGKLEEAMKLLNSMQELRVAVDEDVFVALVRLCEWKRAQEEGSKVYSIALSSMSSLGVELGNAFLAMFVRFGNLVDAWYVFGKMSERNLFSWNVLVGGYAKQGYFDEAMCLYHRMLWVGGVKPDVYTFPCVLRTCGGIPDLARGKEVHVHVVRYGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRRDIISWNAMISGYFENGMCHEGLELFFAMRGLSVDPDLMTLTSVISACELLGDRRLGRDIHAYVITTGFAVDISVCNSLTQMYLNAGSWREAEKLFSRMERKDIVSWTTMISGYEYNFLPDKAIDTYRMMDQDSVKPDEITVAAVLSACATLGDLDTGVELHKLAIKARLISYVIVANNLINMYSKCKCIDKALDIFHNIPRKNVISWTSIIAGLRLNNRCFEALIFLRQM-KMTLQPNAITLTAALAACARIGALMCGKEIHAHVLRTGVGLDDFLPN--ALLDMYVRCGRMNTAW 553          

Query:  118 FHTLSQRTHIPSHVYTHPAAILLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDG---YGTNGLGKAAVDLFNEMEKGTI 1659
            +H +     +   VYT P   +L  C  I +L    ++   +++ G   +      L++++   G    A  +F+ +  +  + ++ ++ GY +N    + +  F  M+   V P +   T ++  C    D R G++IHA++I++GFA ++    ++  MY       EA K+F RM  +D+VSW T+I+GY  N L   A++    M ++  KPD IT+  +L A A  G L  G  +H   ++A   S V ++  L++MYSKC  +  A  IF+ + +K  +SW S+I G   N    EA+ IF + +    QP  +T+  AL ACA +G L  GK +H  V +  +G D  + N+L+ MY +C R++ A   F N   K + SWN ++ GY++ G+ S  +  F +M    ++PD  T +S++   ++  + RQ       +       N+     +VD+  + G +  A K    M        W A+++    +    LG+ +     E++K ++
Sbjct:  183 YHRMLWVGGVKPDVYTFPC--VLRTCGGIPDLARGKEVHVHVVRYGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRRDIISWNAMISGYFENGMCHEGLELFFAMRGLSVDPDLMTLTSVISACELLGDRRLGRDIHAYVITTGFAVDISVCNSLTQMYLNAGSWREAEKLFSRMERKDIVSWTTMISGYEYNFLPDKAIDTYRMMDQDSVKPDEITVAAVLSACATLGDLDTGVELHKLAIKARLISYVIVANNLINMYSKCKCIDKALDIFHNIPRKNVISWTSIIAGLRLNNRCFEAL-IFLRQMKMTLQPNAITLTAALAACARIGALMCGKEIHAHVLRTGVGLDDFLPNALLDMYVRCGRMNTAWSQF-NSQKKDVTSWNILLTGYSERGQGSMVVELFDRMVKSRVRPDEITFISLLCGCSKSQMVRQGLMYFSKMEDYGVTPNLKHYACVVDLLGRAGELQEAHKFIQKMPVTPDPAVWGALLNACRIHHKIDLGELSAQHIFELDKKSV 699          

Query: 1273 NTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEM-EKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAML------GACRTHKNVEL 1929
            N+ + G   NG++ EA+     MQ   +  D    V+++          +   ++ + + +     + +  A + M+ + G +  A  +F  M ER++ +WN ++ GY   G    A+ L++ M   G +KP+  TF CV+  C     +  G +    +   YG E  +D   A++ +  + G +  A     +MP    I  + AM+      G C  H+ +EL
Sbjct:   63 NSQLHGLCANGKLEEAMKLLNSMQELRVAVDEDVFVALVRLCEWKRAQEEGSKVYSIALSSMSSLGVELGNAFLAMFVRFGNLVDAWYVFGKMSERNLFSWNVLVGGYAKQGYFDEAMCLYHRMLWVGGVKPDVYTFPCVLRTCGGIPDLARGKEVHVHVVR-YGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRR-DIISWNAMISGYFENGMC--HEGLEL 284          

Query:  277 LVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGD---NADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLR-ASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDE-GFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQ-----------NMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPME-PGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            LV+L+   G     ++VF+ + ++ +V +++L+           A+  F  M  + V P  +    ++  C +      L  GK++HA+ +  G   N F +  +V MY K  ++  +  +      RDLV+WNT+++   QN     ALE +  M  EG +PD  T+ ++LPA +    L  GK +HAY L+  S +    + +AL+DMY  C  V + R +F+ M  +    WN+MI GY QNE  +EA+ +F  M +  G    + T+   + AC   G   R + +H  V +  L  D  V N+LM MYS+  ++DIA +IF  +  + LV+WNTMI GY  +    +AL    +MQ+            ++KP+S T+++++P+ A LS   + K IH   I+     ++ V +ALVDMYAKCG +  +RK+FD + +++V TWN +I  YG +G G+ A+DL   M    +KPN++TF+ V +ACSHSG+V+EGL+ F  MK DYG+EP+ DHY  +VDLLGRAG++ EA+  +  MP +      + ++LGA R H N+E+GE AA  + +L P    ++VLLANIYS+A LWDK  +VR+ M+ +G++K PGCS ++  +EVH F +G +SHPQS+++  +LETL + ++  GYVPDT+ + H+VE D KE LL  HSEKLAIAFG+LNT+PGT I + KNLRVC DCH ATK+IS +  REII+RD+ RFH FKNGTCSCGDYW
Sbjct:  139 LVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKG-ELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYLETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:  370 LLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFAT-NLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADY---GSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGS---DVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQM-QSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEME-------KG----TIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAAD 1947
            LL+   +++ L +A+  +  M   G++P  Y F  LLK   D  D+  GK+IHAH+   G+   ++     +VN+Y KC      YK+FDR+ ER+ VSWN++I+        ++ALE    M +E  +P S TLV+++ A ++      L++GK +HAY LR    +   I+T L+ MY K G + +++++      +  V+WN+++    QNE   EA+E  ++M+ EG +P   TI   L AC+ L  L  GK +H     LK GS   +  V ++L+ MY  CK+V    ++F  +  + +  WN MI GY+QN    EAL  F  M +S  +  +S TM  V+PA        + + IHG V++   D++ FV   L+DMY++ G +  A ++F  M++R + TWN MI GY  +   + A+ L ++M+       KG    ++KPN IT + ++ +C+    + +G +  A ++K +   + A+    A+VD+  + G L  +     ++P +  IT +  ++ A   H N   G+ A D
Sbjct:   68 LLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNSFIINT-LVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYA--LKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVG--SALVDMYAKCGCLQMSRKVFDQIPQKNVIT-WNVIIMAYGMHGN---GQEAID 604          

Query:  664 WNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFE-SLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADL---GDLERGKFVHKLVDQLKLGS-DVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRT-CFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGT-IKPNDITFLCVISACSHSGLV--EEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKM 1857
            W  ++    ++ L + A+   + M   G KPD+     LL AVAD   + +GK IHA+V +  +    V ++  L+++Y KCG  G    +F+R+ ++  VSWNS+I      E  E A+E F+ MLDE  +P++ T++  + AC++L     L  GK VH     L+ G  +  ++N+L++MY K  ++  +  +  +  G+ LV+WNT++    QN ++ EAL +  +M  + ++PD FT+ SV+PA + L + R  K +H   ++    D+N FV +ALVDMY  C  V + R++FD M +R +  WNAMI GY  N   K A+ LF  ME+   +  N  T   V+ AC  SG    +E +  F   +   GL+        ++D+  R G++  A     KM
Sbjct:   65 WIDLLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAY--GLRKGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKR---GLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKM 466          

Query:  232 IIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKS-----------DGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASF--ESLVNISTALLDMYSKCGSVGTARLIFNRMKQ--KTAVSWNSMI 981
            ++K GL  +   Q  L+ ++   G    A R+F  +ED+  V ++T++ GY  +    DA+    +M++             ++P       +L  C   + L +GKEIHA+ I +  AT++   +A+V+MYAKC  +  + K+FD++P++++++WN II  Y  +G  + A++L+  M  +G KP+ +T +++  A +  G +  G  I  YV++  +  E   +    ++D+  + G +  A  + N M +    A +W+S++
Sbjct:  431 VVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIF-YVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLL 694          

Query:  196 TSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEG-QKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            TSI  L Q    II +G  N+    TKL     + G+   A  +F +V+      ++ L++G++ N S   ++S F  + KS  ++P    + + +       D R G+ IH   +  G  + L   + +V MY K  ++ +A K+FDRMPE+D + WNT+I+GY +N +   ++++   +  E   + D+ TL+ +LPAVA+   L +G  IH+   +    S   + T  + +YSKCG +     +F   ++   V++N+MI GY  N + E ++ +F++++  G +  + T++  +      G L     +H    +    S  SV  +L ++YSK   ++ A K+F     K+L SWN MI GY QNG   +A+S F +MQ     P+  T+  ++ A A+L      KW+H LV  T F+ +I+V TAL+ MYAKCG++  AR+LFD+M +++  TWN MI GYG +G G+ A+++F EM    I P  +TFLCV+ ACSH+GLV+EG + F SM   YG EP++ HY  MVD+LGRAG L  A  FI+ M +EPG +V+  +LGACR HK+  L    ++K+FEL+P   GYHVLL+NI+S    + + A VR+  + + L K PG +L+++    H F SG  SHPQ K IY  LE L  +++ AGY P+T  ++HDVE + +E ++  HSE+LAIAFGL+ T PGT I I KNLRVC DCH  TK IS +T R I+VRD +RFHHFK+G CSCGDYW
Sbjct:   31 TSISHLAQTHAQIILHGFRNDISLLTKLTQRLSDLGAIYYARDIFLSVQRPDVFLFNVLMRGFSVNESPHSSLSVFAHLRKSTDLKPNSSTYAFAISAASGFRDDRAGRVIHGQAVVDGCDSELLLGSNIVKMYFKFWRVEDARKVFDRMPEKDTILWNTMISGYRKNEMYVESIQVFRDLINESCTRLDTTTLLDILPAVAELQELRLGMQIHSLATKTGCYSHDYVLTGFISLYSKCGKIKMGSALFREFRKPDIVAYNAMIHGYTSNGETELSLSLFKELMLSGARLRSSTLVSLVPVS---GHLMLIYAIHGYCLKSNFLSHASVSTALTTVYSKLNEIESARKLFDESPEKSLPSWNAMISGYTQNGLTEDAISLFREMQKSEFSPNPVTITCILSACAQLGALSLGKWVHDLVRSTDFESSIYVSTALIGMYAKCGSIAEARRLFDLMTKKNEVTWNTMISGYGLHGQGQEALNIFYEMLNSGITPTPVTFLCVLYACSHAGLVKEGDEIFNSMIHRYGFEPSVKHYACMVDILGRAGHLQRALQFIEAMSIEPGSSVWETLLGACRIHKDTNLARTVSEKLFELDPDNVGYHVLLSNIHSADRNYPQAATVRQTAKKRKLAKAPGYTLIEIGETPHVFTSGDQSHPQVKEIYEKLEKLEGKMREAGYQPETELALHDVEEEERELMVKVHSERLAIAFGLIATEPGTEIRIIKNLRVCLDCHTVTKLISKITERVIVVRDANRFHHFKDGVCSCGDYW 792          

Query:  181 LLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCR-MKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLG---SDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQN-MKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            L   CT+++    +   ++ +          KLV+L+C  G+ + A   F+ ++++    ++ ++ GY +  +  + +  F   M S G+ P    F  +LK C    D   G +IH   +  GF  +++   +++++Y++ + +  A  +FD MP RD+ SWN +I+GY Q+G AK AL L   ++      DS+T+V+LL A  + G    G +IH+Y ++   ES + +S  L+D+Y++ G +   + +F+RM  +  +SWNS+I  Y  NE    A+ +FQ+M     QP  +T++      + LGD+   + V      L+ G    D+++ N+++ MY+K   VD A  +F  L    ++SWNT+I GYAQNG  SEA+  +  M+ +  +  +  T VSV+PA ++    RQ   +HG +++     ++FV+T+L DMY KCG +  A  LF  +   +   WN +I  +G +G G+ AV LF EM    +KP+ ITF+ ++SACSHSGLV+EG   F  M+ DYG+ P++ HYG MVD+ GRAGQL  A  FI+ M ++P  +++GA+L ACR H NV+LG+ A++ +FE+ P   GYHVLL+N+Y++A  W+ V ++R +   KGL+KTPG S +++ N+V  FY+G+ +HP  + +Y  L  L  ++K  GYVPD   +  DVE D KE +L SHSE+LAIAF L+ T   TTI I KNLRVCGDCH+ TK+IS +T REIIVRD +RFHHFKNG CSCGDYW
Sbjct:   60 LFRYCTNLQSAKCLHARLVVSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKACRTVID---GNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTLSNGLRAM----DSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSRIQPDCLTLISLASILSQLGDIRACRSVQGFT--LRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLLKNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEGVKPDHITFVTLLSACSHSGLVDEGQWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVDLGKIASEHLFEVEPEHVGYHVLLSNMYASAGKWEGVDEIRSIAHGKGLRKTPGWSSMEVDNKVEVFYTGNQTHPMYEEMYRELTALQAKLKMIGYVPDHRFVLQDVEDDEKEHILMSHSERLAIAFALIATPAKTTIRIFKNLRVCGDCHSVTKFISKITEREIIVRDSNRFHHFKNGVCSCGDYW 823          

Query:  193 CTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYH--TLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDE-----------------------------------GFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKL-------GSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKT--LVSWNTMILGYAQNGRVSEALSHFCQMQSQNM--KPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDK-NIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            C +I ++  I   ++  G+   +L  + L+S + + G  S A  +           YH  +L++ Y  N      +  F  M S    P  Y F ++ K CG+ + +R G+  HA  + +GF +N+F   A+V MY++CR +++A K+FD M   D+VSWN+II  YA+ G  K+ALE+  RM  E G +PD+ITLV +LP  A  G+  +GK +H + + +     + +   L+DMY+KCG +  A  +F+ M  K  VSWN+M+ GY Q    E+A+ +F+KM +E                                   G +P  VT++  L  CA +G L  GK +H    +  +       G +  V+N L+ MY+KCK+VD A  +F +L  K   +V+W  MI GY+Q+G  ++AL    +M  ++   +P++FT+   + A A L+  R  K IH   +R   +   +FV   L+DMYAKCG++  AR +FD M  ++  TW +++ GYG +G G+ A+ +F+EM +   K + +T L V+ ACSHSG++++G++YF  MK  +G+ P  +HY  +VDLLGRAG+L+ A   I++MPMEP   V+ A L  CR H  VELGE AA+KI EL     G + LL+N+Y+ A  W  V ++R +M  KG++K PGCS V+      TF+ G  +HP +K IY  L      IK  GYVP+T  ++HDV+ + K+ LL  HSEKLA+A+G+L T  G  I I KNLRVCGDCH A  Y+S +   +II+RD  RFHHFKNG+CSC  YW
Sbjct:   38 CKTISQVKLIHQKLLSFGILTLNL-TSHLISTYISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLFGLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAYALRNQQNAVPLFVSNCLIDMYAKCGSISDARLVFDNMMAKNEVTWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVLYACSHSGMIDQGMEYFNRMKTVFGVSPGPEHYACLVDLLGRAGRLNAALRLIEEMPMEPPPVVWVAFLSCCRIHGKVELGEYAAEKITELASNHDGSYTLLSNLYANAGRWKDVTRIRSLMRHKGVKKRPGCSWVEGIKGTTTFFVGDKTHPHAKEIYQVLLDHMQRIKDIGYVPETGFALHDVDDEEKDDLLFEHSEKLALAYGILTTPQGAAIRITKNLRVCGDCHTAFTYMSRIIDHDIILRDSSRFHHFKNGSCSCKGYW 850          

Query:  184 LELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYG---SPSEAFRVFETVEDKLEVF-YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRM-QEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVS-------------------------------EALSHFCQMQSQN-MKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPD-TNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            L+ C +I EL      + K GL N+    TKLV+  C  G   S S A  VFE  E     F Y++L++GYA +    +A+  F RM + G+ P  Y F + L  C  +     G +IH  ++  G+A +LF   ++V+ YA+C +++ A K+FD M ER++VSW ++I GYA+   AK A++L  RM ++E   P+S+T+V ++ A A    L  G+ ++A++  +  E    + +AL+DMY KC ++  A+ +F+          N+M   YV+     EA+ +F  M+D G +P  ++++ A+ +C+ L ++  GK  H  V +    S  ++ N+L+ MY KC R D A +IF  +  KT+V+WN+++ GY +NG V                                EA+  FC MQSQ  +  D  TM+S+  A   L     AKWI+  + +     ++ + T LVDM+++CG   +A  +F+ +  R V+ W A I      G  + A++LF++M +  +KP+ + F+  ++ACSH GLV++G + F SM + +G+ P   HYG MVDLLGRAG L EA   I+ MPMEP   ++ ++L ACR   NVE+   AA+KI  L P   G +VLL+N+Y++A  W+ +AKVR  M+ KGL+K PG S + +R + H F SG  SHP+   I   L+ +       G+VPD +N + DV+   K  +L+ HSEKLA+A+GL+++  GTTI I KNLRVC DCH+  K+ S V  REII+RD +RFH+ + G CSCGD+W
Sbjct:   39 LKNCKTIDELKMFHRSLTKQGLDNDVSTITKLVARSCELGTRESLSFAKEVFENSESYGTCFMYNSLIRGYASSGLCNEAILLFLRMMNSGISPDKYTFPFGLSACAKSRAKGNGIQIHGLIVKMGYAKDLFVQNSLVHFYAECGELDSARKVFDEMSERNVVSWTSMICGYARRDFAKDAVDLFFRMVRDEEVTPNSVTMVCVISACAKLEDLETGEKVYAFIRNSGIEVNDLMVSALVDMYMKCNAIDVAKRLFDEYGASNLDLCNAMASNYVRQGLTREALGVFNLMMDSGVRPDRISMLSAISSCSQLRNILWGKSCHGYVLRNGFESWDNICNALIDMYMKCHRQDTAFRIFDRMSNKTVVTWNSIVAGYVENGEVDAAWETFETMPEKNIVSWNTIISGLVQGSLFEEAIEVFCSMQSQEGVNADGVTMMSIASACGHLGALDLAKWIYYYIEKNGIQLDVRLGTTLVDMFSRCGDPESAMSIFNSLTNRDVSAWTAAIGAMAMAGNAERAIELFDDMIEQGLKPDGVAFVGALTACSHGGLVQQGKEIFYSMLKLHGVSPEDVHYGCMVDLLGRAGLLEEAVQLIEDMPMEPNDVIWNSLLAACRVQGNVEMAAYAAEKIQVLAPERTGSYVLLSNVYASAGRWNDMAKVRLSMKEKGLRKPPGTSSIQIRGKTHEFTSGDESHPEMPNIEAMLDEVSQRASHLGHVPDLSNVLMDVDEKEKIFMLSRHSEKLAMAYGLISSNKGTTIRIVKNLRVCSDCHSFAKFASKVYNREIILRDNNRFHYIRQGKCSCGDFW 842          

Query:  103 PQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQ---IIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHD--VEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            P+   F+   + + +    YT P+ I  + C  + +      +   I+  G  ++      LV ++   G  + A +VF+ +  +  V +++L+ GY+ +    +A+  +  +K+  + P  +  + +L   G+   +++G+ +H   + SG  + +     +V MY K R+  +A ++FD M  RD VS+NT+I GY +  + + ++ + +   ++  KPD +T+ ++L A      L + K I+ Y+L+A F     +   L+D+Y+KCG + TAR +FN M+ K  VSWNS+I GY+Q+ D  EAM++F+ M+    Q  ++T +  +     L DL+ GK +H    +  +  D+SV N+L+ MY+KC  V  + KIF ++     V+WNT+I    + G  +  L    QM+   + PD  T +  +P  A L+  R  K IH  ++R  ++  + +  AL++MY+KCG +  + ++F+ M  R V TW  MI  YG  G G+ A++ F +MEK  I P+ + F+ +I ACSHSGLV+EGL  F  MK  Y ++P ++HY  +VDLL R+ ++S+A +FIQ MP++P  +++ ++L ACRT  ++E  ER + +I ELNP + GY +L +N Y+    WDKV+ +RK ++ K + K PG S +++   VH F SG  S PQS+ IY  LE L   +   GY+PD   +     E + K +L+  HSE+LAIAFGLLNT PGT + + KNLRVCGDCH  TK IS + GREI+VRD +RFH FK+GTCSC D W
Sbjct:   88 PEALEFYGKLRESKVSPDKYTFPSVI--KACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQF-KPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIVPDSVVFIAIIYACSHSGLVDEGLACFEKMKTHYKIDPMIEHYACVVDLLSRSQKISKAEEFIQAMPIKPDASIWASVLRACRTSGDMETAERVSRRIIELNPDDPGYSILASNAYAALRKWDKVSLIRKSLKDKHITKNPGYSWIEVGKNVHVFSSGDDSAPQSEAIYKSLEILYSLMAKEGYIPDPREVSQNLEEEEEKRRLICGHSERLAIAFGLLNTEPGTPLQVMKNLRVCGDCHEVTKLISKIVGREILVRDANRFHLFKDGTCSCKDRW 882          

Query:  184 LELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVF-YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLII---GKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFG 1887
            L   +++ EL +I  L+I  GL +   F  KL+  + ++  P+ +  VF  V     V+ ++++++ ++KN    +A+ F+ +++   V P  Y F  ++K C    D   G  ++  ++  GF ++LF   A+V+MY++   +  A ++FD MP RDLVSWN++I+GY+ +G  + ALE+   ++     PDS T+ ++LPA   +G+L++   G+ +H + L++   S+V ++  L+ MY K      AR +F+ M  + +VS+N+MI GY++ E  EE++ +F + LD+ F+P  +T+   L AC  L DL   K+++  + +     + +V N L+ +Y+KC  +  A  +F ++  K  VSWN++I GY Q+G + EA+  F  M     + D  T + +I     L+  +  K +H   I++    ++ V  AL+DMYAKCG V  + K+F  M      TWN +I      G     + +  +M K  + P+  TFL  +  C+       G +    +   +G E  +    A++++  + G L  +    ++M     +T  G
Sbjct:   14 LSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPA---FGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLR-FGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTG 580          

Query: 1393 ALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPM 1863
            AL+  S   + + IH LVI    D + F    L+D Y+      ++  +F  +   ++V  WN++I  +  NGL   A++ + ++ +  + P+  TF  VI AC+     E G   +  +  D G E  +    A+VD+  R G L+ A     +MP+
Sbjct:   13 ALSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQIL-DMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPV 169          

Query:  517 KEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMK--QKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            K+IHA L+  G   + F +T +++  +    I  A ++FD +P   +  WN II GY++N   + AL +   MQ     PDS T   LL A +    L +G+ +HA V R  F++ V +   L+ +Y+KC  +G+AR +F  +   ++T VSW +++  Y QN +  EA+EIF +M     +P  V ++  L+A   L DL++G+ +H  V ++ L  +  ++ SL +MY+KC +V  A  +F  +    L+ WN MI GYA+NG   EA+  F +M +++++PD+ ++ S I A A++    QA+ ++  V R+ +  ++F+ +AL+DM+AKCG+V  AR +FD   +R V  W+AMI GYG +G  + A+ L+  ME+G + PND+TFL ++ AC+HSG+V EG  +F  M  D+ + P   HY  ++DLLGRAG L +A++ I+ MP++PG+TV+GA+L AC+ H++VELGE AA ++F ++P   G++V L+N+Y+ A LWD+VA+VR  M+ KGL K  GCS V++R  +  F  G  SHP+ + I   +E +   +K  G+V + + S+HD+  +  E+ L SHSE++AIA+GL++T  GT + I KNLR C +CH ATK IS +  REI+VRD +RFHHFK+G CSCGDYW
Sbjct:   38 KQIHARLLVLGLQFSGFLITKLIHASSSFGDITFARQVFDDLPRPQIFPWNAIIRGYSRNNHFQDALLMYSNMQLARVSPDSFTFPHLLKACSGLSHLQMGRFVHAQVFRLGFDADVFVQNGLIALYAKCRRLGSARTVFEGLPLPERTIVSWTAIVSAYAQNGEPMEALEIFSQMRKMDVKPDWVALVSVLNAFTCLQDLKQGRSIHASVVKMGLEIEPDLLISLNTMYAKCGQVATAKILFDKMKSPNLILWNAMISGYAKNGYAREAIDMFHEMINKDVRPDTISITSAISACAQVGSLEQARSMYEYVGRSDYRDDVFISSALIDMFAKCGSVEGARLVFDRTLDRDVVVWSAMIVGYGLHGRAREAISLYRAMERGGVHPNDVTFLGLLMACNHSGMVREGWWFFNRM-ADHKINPQQQHYACVIDLLGRAGHLDQAYEVIKCMPVQPGVTVWGALLSACKKHRHVELGEYAAQQLFSIDPSNTGHYVQLSNLYAAARLWDRVAEVRVRMKEKGLNKDVGCSWVEVRGRLEAFRVGDKSHPRYEEIERQVEWIESRLKEGGFVANKDASLHDLNDEEAEETLCSHSERIAIAYGLISTPQGTPLRITKNLRACVNCHAATKLISKLVDREIVVRDTNRFHHFKDGVCSCGDYW 694          

Query:  175 AILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFD--RMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMI 1587
            A L++  T   +L QI   ++  GL       TKL+    ++G  + A +VF+ +       ++ +++GY++N+   DA+  +  M+   V P  + F +LLK C   + L+ G+ +HA +   GF  ++F    ++ +YAKCR++  A  +F+   +PER +VSW  I++ YAQNG    ALE+  +M++   KPD + LV++L A      L  G+SIHA V++   E   ++  +L  MY+KCG V TA+++F++MK    + WN+MI GY +N  A EA+++F +M+++  +P  ++I  A+ ACA +G LE+ + +++ V +     DV + ++L+ M++KC  V+ A  +F   L + +V W+ MI+GY  +GR  EA+S +  M+   + P+  T + ++ A     + R+  W    +     +        ++D+  + G +  A ++   M  +  VT W A++
Sbjct:   25 ASLIDSATHKAQLKQIHARLLVLGLQFSGFLITKLIHASSSFGDITFARQVFDDLPRPQIFPWNAIIRGYSRNNHFQDALLMYSNMQLARVSPDSFTFPHLLKACSGLSHLQMGRFVHAQVFRLGFDADVFVQNGLIALYAKCRRLGSARTVFEGLPLPERTIVSWTAIVSAYAQNGEPMEALEIFSQMRKMDVKPDWVALVSVLNAFTCLQDLKQGRSIHASVVKMGLEIEPDLLISLNTMYAKCGQVATAKILFDKMKSPNLILWNAMISGYAKNGYAREAIDMFHEMINKDVRPDTISITSAISACAQVGSLEQARSMYEYVGRSDYRDDVFISSALIDMFAKCGSVEGARLVFDRTLDRDVVVWSAMIVGYGLHGRAREAISLYRAMERGGVHPNDVTFLGLLMACNHSGMVREGWWFFNRMADHKINPQQQHYACVIDLLGRAGHLDQAYEVIKCMPVQPGVTVWGALL 498          

Query:    1 MSSQLLHYTALLPITNSIXXXXXXXXXXXXXISAPQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            MSSQL+ ++ +  I N                  P  +  H LS+R +IP++VY HPAA+LLE C+S+KEL QI+PL+ KNGLY EH FQTKLVSLFC YGS  EA RVFE ++ KL V YHT+LKG+AK S L  A+ FF RM+ D V PVVYNFTYLLKVCGD A+LR GKEIH  L+ SGF+ +LFAMT + NMYAKCRQ+NEA K+FDRMPERDLVSWNTI+AGY+QNG+A++ALE+V  M EE  KP  IT+V++LPAV+    + +GK IH Y +R+ F+SLVNISTAL+DMY+KCGS+ TAR +F+ M ++  VSWNSMID YVQNE+ +EAM IFQKMLDEG +PT+V++M ALHACADLGDLERG+F+HKL  +L L  +VSV+NSL+SMY KCK VD AA +F  L  +TLVSWN MILG+AQNGR  +AL++F QM+S+ +KPD+FT VSVI A+AELS+T  AKWIHG+V+R+C DKN+FV TALVDMYAKCGA+  AR +FDMM ERHVTTWNAMIDGYGT+G GKAA++LF EM+KGTIKPN +TFL VISACSHSGLVE GL+ F  MKE+Y +E +MDHYGAMVDLLGRAG+L+EAWDFI +MP++P + V+GAMLGAC+ HKNV   E+AA+++FELNP +GGYHVLLANIY  AS+W+KV +VR  M  +GL+KTPGCS+V+++NEVH+F+SGST+HP SK+IY FLE L   IK AGYVPDTN +  VE DVKEQLL++HSEKLAI+FGLLNTT GTTIH+RKNLRVC DCHNATKYISLVTGREI+VRDM RFHHFKNG CSCGDYW
Sbjct:    1 MSSQLVQFSTVPQIPN------------------PPSRHRHFLSERNYIPANVYEHPAALLLERCSSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSKKIYAFLEKLICHIKEAGYVPDTNLVLGVENDVKEQLLSTHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIVVRDMQRFHHFKNGACSCGDYW 809          

Query:  181 LLELCT---SIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHF-CQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +L+LC    S+K+  ++   I  NG   +    +KL  ++ N G   EA RVF+ V+ +  +F++ L+   AK+     ++  F +M S GV    Y F+ + K       +  G+++H  ++ SGF        ++V  Y K ++++ A K+FD M ERD++SWN+II GY  NGLA+  L + ++M   G + D  T+V++    AD   + +G+++H+  ++A F         LLDMYSKCG + +A+ +F  M  ++ VS+ SMI GY +   A EA+++F++M +EG  P   T+   L+ CA    L+ GK VH+ + +  LG D+ V N+LM MY+KC  +  A  +F  +  K ++SWNT+I GY++N   +EALS F   ++ +   PD  T+  V+PA A LS   + + IHG ++R  +  +  V  +LVDMYAKCGA+  A  LFD +  + + +W  MI GYG +G GK A+ LFN+M +  I+ ++I+F+ ++ ACSHSGLV+EG ++F  M+ +  +EP ++HY  +VD+L R G L +A+ FI+ MP+ P  T++GA+L  CR H +V+L E+ A+K+FEL P   GY+VL+ANIY+ A  W++V ++RK +  +GL+K PGCS ++++  V+ F +G +S+P+++ I  FL  +   +   GY P T  ++ D E   KE+ L  HSEKLA+A G++++  G  I + KNLRVCGDCH   K++S +T REI++RD +RFH FK+G CSC  +W
Sbjct:  100 VLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDRHVANSLVDMYAKCGALLLAHMLFDDIASKDLVSWTVMIAGYGMHGFGKEAIALFNQMRQAGIEADEISFVSLLYACSHSGLVDEGWRFFNIMRHECKIEPTVEHYACIVDMLARTGDLIKAYRFIENMPIPPDATIWGALLCGCRIHHDVKLAEKVAEKVFELEPENTGYYVLMANIYAEAEKWEQVKRLRKRIGQRGLRKNPGCSWIEIKGRVNIFVAGDSSNPETENIEAFLRKVRARMIEEGYSPLTKYALIDAEEMEKEEALCGHSEKLAMALGIISSGHGKIIRVTKNLRVCGDCHEMAKFMSKLTRREIVLRDSNRFHQFKDGHCSCRGFW 871          

Query:  646 ERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKE-DYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGI---TVFGAMLGACRTHKNVEL 1929
            +R +   NT +  + ++G  + A++L+    +    P   TL ++L   AD  SL  GK +  ++    F    N+ + L  MY+ CG +  A  +F+ +K + A+ WN +++   ++ D   ++ +F+KM+  G +  + T      + + L  +  G+ +H  + +   G   SV NSL++ Y K +RVD A K+F  +  + ++SWN++I GY  NG   + LS F QM    ++ D  T+VSV    A+  +    + +H + ++ CF +       L+DMY+KCG + +A+ +F  M +R V ++ +MI GY   GL   AV LF EME+  I P+  T   V++ C+   L++EG +    +KE D G +  + +  A++D+  + G + EA     +M ++  I   T+ G     C  ++ + L
Sbjct:   58 DRSVTDANTQLRRFCESGNLENAVKLLCVSGKWDIDPR--TLCSVLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSN--ALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSL 485          

Query:  280 VSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMK-SDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGY--VPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGD 2475
            +++F  +G+  +A+ VF  + ++    ++ L+ GYAK     +AM  + RM    GV+P VY F  +L+ CG   DL RGKE+H H++  G+  ++  + A++ MY KC  +  A  +FDRMP RD++SWN +I+GY +NG+    LEL   M+     PD +TL +++ A    G   +G+ IHAYV+   F   +++  +L  MY   GS   A  +F+RM++K  VSW +MI GY  N   ++A++ ++ M  +  +P  +T+   L ACA LGDL+ G  +HKL  + +L S V V N+L++MYSKCK +D A  IF N+  K ++SW ++I G   N R  EAL    QM+   ++P++ T+ + + A A +      K IH  V+RT    + F+  AL+DMY +CG ++TA   F+   ++ VT+WN ++ GY   G G   V+LF+ M K  ++P++ITF+ ++  CS S +V +GL YF+ M EDYG+ P + HY  +VDLLGRAG+L EA  FIQKMP+ P   V+GA+L ACR H  ++LGE +A  IFEL+    GY++LL N+Y+    W +VAKVR+MM+  GL    GCS V+++ +VH F S    HPQ+K I T LE   +++   G   + +++S+ + E   ++++   HSE+ AIAFGL+NT PG  I + KNL +C +CH+  K+IS    REI VRD   FHHFK+G CSCGD
Sbjct:  136 LAMFVRFGNLVDAWYVFGKMSERNLFSWNVLVGGYAKQGYFDEAMCLYHRMLWVGGVKPDVYTFPCVLRTCGGIPDLARGKEVHVHVVRYGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRRDIISWNAMISGYFENGMCHEGLELFFAMRGLSVDPDLMTLTSVISACELLGDRRLGRDIHAYVITTGFAVDISVCNSLTQMYLNAGSWREAEKLFSRMERKDIVSWTTMISGYEYNFLPDKAIDTYRMMDQDSVKPDEITVAAVLSACATLGDLDTGVELHKLAIKARLISYVIVANNLINMYSKCKCIDKALDIFHNIPRKNVISWTSIIAGLRLNNRCFEALIFLRQMK-MTLQPNAITLTAALAACARIGALMCGKEIHAHVLRTGVGLDDFLPNALLDMYVRCGRMNTAWSQFN-SQKKDVTSWNILLTGYSERGQGSMVVELFDRMVKSRVRPDEITFISLLCGCSKSQMVRQGLMYFSKM-EDYGVTPNLKHYACVVDLLGRAGELQEAHKFIQKMPVTPDPAVWGALLNACRIHHKIDLGELSAQHIFELDKKSVGYYILLCNLYADCGKWREVAKVRRMMKENGLTVDAGCSWVEVKGKVHAFLSDDKYHPQTKEINTVLEGFYEKMSEVGLTKISESSSMDETEIS-RDEIFCGHSERKAIAFGLINTVPGMPIWVTKNLSMCENCHDTVKFISKTVRREISVRDAEHFHHFKDGECSCGD 866          

Query:  238 KNGLYNEHLFQTKLVSLFCNYG------SPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRM-QEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFAS-MKEDYGLEPAMDHYGAMVDLLGRAGQLSEAW 1839
            K+  +    ++ + V+ + N+G        S+   V  +       F ++ L G   N  L +AM     M+   V      F  L+++C        G ++++  +SS  +  +    A + M+ +   + +A+ +F +M ER+L SWN ++ GYA+ G    A+ L  RM    G KPD  T   +L        L  GK +H +V+R  +E  +++  AL+ MY KCG V +ARL+F+RM ++  +SWN+MI GY +N    E +E+F  M      P  +T+   + AC  LGD   G+ +H  V       D+SV NSL  MY        A K+F  +  K +VSW TMI GY  N    +A+  +  M   ++KPD  T+ +V+ A A L        +H L I+      + V   L++MY+KC  +  A  +F  +  ++V +W ++I G   N     A+    +M K T++PN IT    ++AC+  G +  G +  A  ++   GL+  + +  A++D+  R G+++ AW
Sbjct:   16 KSNSFQSKAYKQRNVNFYWNFGIRRLFLRKSQGLSVLSSSSSSTH-FSNSQLHGLCANGKLEEAMKLLNSMQELRVAVDEDVFVALVRLCEWKRAQEEGSKVYSIALSSMSSLGVELGNAFLAMFVRFGNLVDAWYVFGKMSERNLFSWNVLVGGYAKQGYFDEAMCLYHRMLWVGGVKPDVYTFPCVLRTCGGIPDLARGKEVHVHVVRYGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRRDIISWNAMISGYFENGMCHEGLELFFAMRGLSVDPDLMTLTSVISACELLGDRRLGRDIHAYVITTGFAVDISVCNSLTQMYLNAGSWREAEKLFSRMERKDIVSWTTMISGYEYNFLPDKAIDTYRMMDQDSVKPDEITVAAVLSACATLGDLDTGVELHKLAIKARLISYVIVANNLINMYSKCKCIDKALDIFHNIPRKNVISWTSIIAGLRLNNRCFEALIFLRQM-KMTLQPNAITLTAALAACARIGALMCGKEIHAHVLRTGVGLDDFLPN--ALLDMYVRCGRMNTAW 553          

Query:  118 FHTLSQRTHIPSHVYTHPAAILLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDG---YGTNGLGKAAVDLFNEMEKGTI 1659
            +H +     +   VYT P   +L  C  I +L    ++   +++ G   +      L++++   G    A  +F+ +  +  + ++ ++ GY +N    + +  F  M+   V P +   T ++  C    D R G++IHA++I++GFA ++    ++  MY       EA K+F RM  +D+VSW T+I+GY  N L   A++    M ++  KPD IT+  +L A A  G L  G  +H   ++A   S V ++  L++MYSKC  +  A  IF+ + +K  +SW S+I G   N    EA+ IF + +    QP  +T+  AL ACA +G L  GK +H  V +  +G D  + N+L+ MY +C R++ A   F N   K + SWN ++ GY++ G+ S  +  F +M    ++PD  T +S++   ++  + RQ       +       N+     +VD+  + G +  A K    M        W A+++    +    LG+ +     E++K ++
Sbjct:  183 YHRMLWVGGVKPDVYTFPC--VLRTCGGIPDLARGKEVHVHVVRYGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRRDIISWNAMISGYFENGMCHEGLELFFAMRGLSVDPDLMTLTSVISACELLGDRRLGRDIHAYVITTGFAVDISVCNSLTQMYLNAGSWREAEKLFSRMERKDIVSWTTMISGYEYNFLPDKAIDTYRMMDQDSVKPDEITVAAVLSACATLGDLDTGVELHKLAIKARLISYVIVANNLINMYSKCKCIDKALDIFHNIPRKNVISWTSIIAGLRLNNRCFEAL-IFLRQMKMTLQPNAITLTAALAACARIGALMCGKEIHAHVLRTGVGLDDFLPNALLDMYVRCGRMNTAWSQF-NSQKKDVTSWNILLTGYSERGQGSMVVELFDRMVKSRVRPDEITFISLLCGCSKSQMVRQGLMYFSKMEDYGVTPNLKHYACVVDLLGRAGELQEAHKFIQKMPVTPDPAVWGALLNACRIHHKIDLGELSAQHIFELDKKSV 699          

Query: 1273 NTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEM-EKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAML------GACRTHKNVEL 1929
            N+ + G   NG++ EA+     MQ   +  D    V+++          +   ++ + + +     + +  A + M+ + G +  A  +F  M ER++ +WN ++ GY   G    A+ L++ M   G +KP+  TF CV+  C     +  G +    +   YG E  +D   A++ +  + G +  A     +MP    I  + AM+      G C  H+ +EL
Sbjct:   63 NSQLHGLCANGKLEEAMKLLNSMQELRVAVDEDVFVALVRLCEWKRAQEEGSKVYSIALSSMSSLGVELGNAFLAMFVRFGNLVDAWYVFGKMSERNLFSWNVLVGGYAKQGYFDEAMCLYHRMLWVGGVKPDVYTFPCVLRTCGGIPDLARGKEVHVHVVR-YGYELDIDVVNALITMYVKCGDVKSARLLFDRMPRR-DIISWNAMISGYFENGMC--HEGLEL 284          

Query:  277 LVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGD---NADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLR-ASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDE-GFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQ-----------NMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPME-PGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            LV+L+   G     ++VF+ + ++ +V +++L+           A+  F  M  + V P  +    ++  C +      L  GK++HA+ +  G   N F +  +V MY K  ++  +  +      RDLV+WNT+++   QN     ALE +  M  EG +PD  T+ ++LPA +    L  GK +HAY L+  S +    + +AL+DMY  C  V + R +F+ M  +    WN+MI GY QNE  +EA+ +F  M +  G    + T+   + AC   G   R + +H  V +  L  D  V N+LM MYS+  ++DIA +IF  +  + LV+WNTMI GY  +    +AL    +MQ+            ++KP+S T+++++P+ A LS   + K IH   I+     ++ V +ALVDMYAKCG +  +RK+FD + +++V TWN +I  YG +G G+ A+DL   M    +KPN++TF+ V +ACSHSG+V+EGL+ F  MK DYG+EP+ DHY  +VDLLGRAG++ EA+  +  MP +      + ++LGA R H N+E+GE AA  + +L P    ++VLLANIYS+A LWDK  +VR+ M+ +G++K PGCS ++  +EVH F +G +SHPQS+++  +LETL + ++  GYVPDT+ + H+VE D KE LL  HSEKLAIAFG+LNT+PGT I + KNLRVC DCH ATK+IS +  REII+RD+ RFH FKNGTCSCGDYW
Sbjct:  139 LVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKG-ELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYLETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:  370 LLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFAT-NLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADY---GSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGS---DVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQM-QSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEME-------KG----TIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAAD 1947
            LL+   +++ L +A+  +  M   G++P  Y F  LLK   D  D+  GK+IHAH+   G+   ++     +VN+Y KC      YK+FDR+ ER+ VSWN++I+        ++ALE    M +E  +P S TLV+++ A ++      L++GK +HAY LR    +   I+T L+ MY K G + +++++      +  V+WN+++    QNE   EA+E  ++M+ EG +P   TI   L AC+ L  L  GK +H     LK GS   +  V ++L+ MY  CK+V    ++F  +  + +  WN MI GY+QN    EAL  F  M +S  +  +S TM  V+PA        + + IHG V++   D++ FV   L+DMY++ G +  A ++F  M++R + TWN MI GY  +   + A+ L ++M+       KG    ++KPN IT + ++ +C+    + +G +  A ++K +   + A+    A+VD+  + G L  +     ++P +  IT +  ++ A   H N   G+ A D
Sbjct:   68 LLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNSFIINT-LVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYA--LKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVG--SALVDMYAKCGCLQMSRKVFDQIPQKNVIT-WNVIIMAYGMHGN---GQEAID 604          

Query:  664 WNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFE-SLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADL---GDLERGKFVHKLVDQLKLGS-DVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRT-CFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGT-IKPNDITFLCVISACSHSGLV--EEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKM 1857
            W  ++    ++ L + A+   + M   G KPD+     LL AVAD   + +GK IHA+V +  +    V ++  L+++Y KCG  G    +F+R+ ++  VSWNS+I      E  E A+E F+ MLDE  +P++ T++  + AC++L     L  GK VH     L+ G  +  ++N+L++MY K  ++  +  +  +  G+ LV+WNT++    QN ++ EAL +  +M  + ++PD FT+ SV+PA + L + R  K +H   ++    D+N FV +ALVDMY  C  V + R++FD M +R +  WNAMI GY  N   K A+ LF  ME+   +  N  T   V+ AC  SG    +E +  F   +   GL+        ++D+  R G++  A     KM
Sbjct:   65 WIDLLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAY--GLRKGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKR---GLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKM 466          

Query:  232 IIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKS-----------DGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASF--ESLVNISTALLDMYSKCGSVGTARLIFNRMKQ--KTAVSWNSMI 981
            ++K GL  +   Q  L+ ++   G    A R+F  +ED+  V ++T++ GY  +    DA+    +M++             ++P       +L  C   + L +GKEIHA+ I +  AT++   +A+V+MYAKC  +  + K+FD++P++++++WN II  Y  +G  + A++L+  M  +G KP+ +T +++  A +  G +  G  I  YV++  +  E   +    ++D+  + G +  A  + N M +    A +W+S++
Sbjct:  431 VVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIF-YVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLL 694          

Query:  196 TSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEG-QKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            TSI  L Q    II +G  N+    TKL     + G+   A  +F +V+      ++ L++G++ N S   ++S F  + KS  ++P    + + +       D R G+ IH   +  G  + L   + +V MY K  ++ +A K+FDRMPE+D + WNT+I+GY +N +   ++++   +  E   + D+ TL+ +LPAVA+   L +G  IH+   +    S   + T  + +YSKCG +     +F   ++   V++N+MI GY  N + E ++ +F++++  G +  + T++  +      G L     +H    +    S  SV  +L ++YSK   ++ A K+F     K+L SWN MI GY QNG   +A+S F +MQ     P+  T+  ++ A A+L      KW+H LV  T F+ +I+V TAL+ MYAKCG++  AR+LFD+M +++  TWN MI GYG +G G+ A+++F EM    I P  +TFLCV+ ACSH+GLV+EG + F SM   YG EP++ HY  MVD+LGRAG L  A  FI+ M +EPG +V+  +LGACR HK+  L    ++K+FEL+P   GYHVLL+NI+S    + + A VR+  + + L K PG +L+++    H F SG  SHPQ K IY  LE L  +++ AGY P+T  ++HDVE + +E ++  HSE+LAIAFGL+ T PGT I I KNLRVC DCH  TK IS +T R I+VRD +RFHHFK+G CSCGDYW
Sbjct:   31 TSISHLAQTHAQIILHGFRNDISLLTKLTQRLSDLGAIYYARDIFLSVQRPDVFLFNVLMRGFSVNESPHSSLSVFAHLRKSTDLKPNSSTYAFAISAASGFRDDRAGRVIHGQAVVDGCDSELLLGSNIVKMYFKFWRVEDARKVFDRMPEKDTILWNTMISGYRKNEMYVESIQVFRDLINESCTRLDTTTLLDILPAVAELQELRLGMQIHSLATKTGCYSHDYVLTGFISLYSKCGKIKMGSALFREFRKPDIVAYNAMIHGYTSNGETELSLSLFKELMLSGARLRSSTLVSLVPVS---GHLMLIYAIHGYCLKSNFLSHASVSTALTTVYSKLNEIESARKLFDESPEKSLPSWNAMISGYTQNGLTEDAISLFREMQKSEFSPNPVTITCILSACAQLGALSLGKWVHDLVRSTDFESSIYVSTALIGMYAKCGSIAEARRLFDLMTKKNEVTWNTMISGYGLHGQGQEALNIFYEMLNSGITPTPVTFLCVLYACSHAGLVKEGDEIFNSMIHRYGFEPSVKHYACMVDILGRAGHLQRALQFIEAMSIEPGSSVWETLLGACRIHKDTNLARTVSEKLFELDPDNVGYHVLLSNIHSADRNYPQAATVRQTAKKRKLAKAPGYTLIEIGETPHVFTSGDQSHPQVKEIYEKLEKLEGKMREAGYQPETELALHDVEEEERELMVKVHSERLAIAFGLIATEPGTEIRIIKNLRVCLDCHTVTKLISKITERVIVVRDANRFHHFKDGVCSCGDYW 792          

Query:  181 LLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCR-MKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLG---SDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQN-MKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            L   CT+++    +   ++ +          KLV+L+C  G+ + A   F+ ++++    ++ ++ GY +  +  + +  F   M S G+ P    F  +LK C    D   G +IH   +  GF  +++   +++++Y++ + +  A  +FD MP RD+ SWN +I+GY Q+G AK AL L   ++      DS+T+V+LL A  + G    G +IH+Y ++   ES + +S  L+D+Y++ G +   + +F+RM  +  +SWNS+I  Y  NE    A+ +FQ+M     QP  +T++      + LGD+   + V      L+ G    D+++ N+++ MY+K   VD A  +F  L    ++SWNT+I GYAQNG  SEA+  +  M+ +  +  +  T VSV+PA ++    RQ   +HG +++     ++FV+T+L DMY KCG +  A  LF  +   +   WN +I  +G +G G+ AV LF EM    +KP+ ITF+ ++SACSHSGLV+EG   F  M+ DYG+ P++ HYG MVD+ GRAGQL  A  FI+ M ++P  +++GA+L ACR H NV+LG+ A++ +FE+ P   GYHVLL+N+Y++A  W+ V ++R +   KGL+KTPG S +++ N+V  FY+G+ +HP  + +Y  L  L  ++K  GYVPD   +  DVE D KE +L SHSE+LAIAF L+ T   TTI I KNLRVCGDCH+ TK+IS +T REIIVRD +RFHHFKNG CSCGDYW
Sbjct:   60 LFRYCTNLQSAKCLHARLVVSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKACRTVID---GNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTLSNGLRAM----DSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSRIQPDCLTLISLASILSQLGDIRACRSVQGFT--LRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLLKNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEGVKPDHITFVTLLSACSHSGLVDEGQWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVDLGKIASEHLFEVEPEHVGYHVLLSNMYASAGKWEGVDEIRSIAHGKGLRKTPGWSSMEVDNKVEVFYTGNQTHPMYEEMYRELTALQAKLKMIGYVPDHRFVLQDVEDDEKEHILMSHSERLAIAFALIATPAKTTIRIFKNLRVCGDCHSVTKFISKITEREIIVRDSNRFHHFKNGVCSCGDYW 823          

Query:  193 CTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYH--TLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDE-----------------------------------GFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKL-------GSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKT--LVSWNTMILGYAQNGRVSEALSHFCQMQSQNM--KPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDK-NIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            C +I ++  I   ++  G+   +L  + L+S + + G  S A  +           YH  +L++ Y  N      +  F  M S    P  Y F ++ K CG+ + +R G+  HA  + +GF +N+F   A+V MY++CR +++A K+FD M   D+VSWN+II  YA+ G  K+ALE+  RM  E G +PD+ITLV +LP  A  G+  +GK +H + + +     + +   L+DMY+KCG +  A  +F+ M  K  VSWN+M+ GY Q    E+A+ +F+KM +E                                   G +P  VT++  L  CA +G L  GK +H    +  +       G +  V+N L+ MY+KCK+VD A  +F +L  K   +V+W  MI GY+Q+G  ++AL    +M  ++   +P++FT+   + A A L+  R  K IH   +R   +   +FV   L+DMYAKCG++  AR +FD M  ++  TW +++ GYG +G G+ A+ +F+EM +   K + +T L V+ ACSHSG++++G++YF  MK  +G+ P  +HY  +VDLLGRAG+L+ A   I++MPMEP   V+ A L  CR H  VELGE AA+KI EL     G + LL+N+Y+ A  W  V ++R +M  KG++K PGCS V+      TF+ G  +HP +K IY  L      IK  GYVP+T  ++HDV+ + K+ LL  HSEKLA+A+G+L T  G  I I KNLRVCGDCH A  Y+S +   +II+RD  RFHHFKNG+CSC  YW
Sbjct:   38 CKTISQVKLIHQKLLSFGILTLNL-TSHLISTYISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLFGLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAYALRNQQNAVPLFVSNCLIDMYAKCGSISDARLVFDNMMAKNEVTWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVLYACSHSGMIDQGMEYFNRMKTVFGVSPGPEHYACLVDLLGRAGRLNAALRLIEEMPMEPPPVVWVAFLSCCRIHGKVELGEYAAEKITELASNHDGSYTLLSNLYANAGRWKDVTRIRSLMRHKGVKKRPGCSWVEGIKGTTTFFVGDKTHPHAKEIYQVLLDHMQRIKDIGYVPETGFALHDVDDEEKDDLLFEHSEKLALAYGILTTPQGAAIRITKNLRVCGDCHTAFTYMSRIIDHDIILRDSSRFHHFKNGSCSCKGYW 850          

Query:  184 LELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYG---SPSEAFRVFETVEDKLEVF-YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRM-QEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVS-------------------------------EALSHFCQMQSQN-MKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPD-TNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            L+ C +I EL      + K GL N+    TKLV+  C  G   S S A  VFE  E     F Y++L++GYA +    +A+  F RM + G+ P  Y F + L  C  +     G +IH  ++  G+A +LF   ++V+ YA+C +++ A K+FD M ER++VSW ++I GYA+   AK A++L  RM ++E   P+S+T+V ++ A A    L  G+ ++A++  +  E    + +AL+DMY KC ++  A+ +F+          N+M   YV+     EA+ +F  M+D G +P  ++++ A+ +C+ L ++  GK  H  V +    S  ++ N+L+ MY KC R D A +IF  +  KT+V+WN+++ GY +NG V                                EA+  FC MQSQ  +  D  TM+S+  A   L     AKWI+  + +     ++ + T LVDM+++CG   +A  +F+ +  R V+ W A I      G  + A++LF++M +  +KP+ + F+  ++ACSH GLV++G + F SM + +G+ P   HYG MVDLLGRAG L EA   I+ MPMEP   ++ ++L ACR   NVE+   AA+KI  L P   G +VLL+N+Y++A  W+ +AKVR  M+ KGL+K PG S + +R + H F SG  SHP+   I   L+ +       G+VPD +N + DV+   K  +L+ HSEKLA+A+GL+++  GTTI I KNLRVC DCH+  K+ S V  REII+RD +RFH+ + G CSCGD+W
Sbjct:   39 LKNCKTIDELKMFHRSLTKQGLDNDVSTITKLVARSCELGTRESLSFAKEVFENSESYGTCFMYNSLIRGYASSGLCNEAILLFLRMMNSGISPDKYTFPFGLSACAKSRAKGNGIQIHGLIVKMGYAKDLFVQNSLVHFYAECGELDSARKVFDEMSERNVVSWTSMICGYARRDFAKDAVDLFFRMVRDEEVTPNSVTMVCVISACAKLEDLETGEKVYAFIRNSGIEVNDLMVSALVDMYMKCNAIDVAKRLFDEYGASNLDLCNAMASNYVRQGLTREALGVFNLMMDSGVRPDRISMLSAISSCSQLRNILWGKSCHGYVLRNGFESWDNICNALIDMYMKCHRQDTAFRIFDRMSNKTVVTWNSIVAGYVENGEVDAAWETFETMPEKNIVSWNTIISGLVQGSLFEEAIEVFCSMQSQEGVNADGVTMMSIASACGHLGALDLAKWIYYYIEKNGIQLDVRLGTTLVDMFSRCGDPESAMSIFNSLTNRDVSAWTAAIGAMAMAGNAERAIELFDDMIEQGLKPDGVAFVGALTACSHGGLVQQGKEIFYSMLKLHGVSPEDVHYGCMVDLLGRAGLLEEAVQLIEDMPMEPNDVIWNSLLAACRVQGNVEMAAYAAEKIQVLAPERTGSYVLLSNVYASAGRWNDMAKVRLSMKEKGLRKPPGTSSIQIRGKTHEFTSGDESHPEMPNIEAMLDEVSQRASHLGHVPDLSNVLMDVDEKEKIFMLSRHSEKLAMAYGLISSNKGTTIRIVKNLRVCSDCHSFAKFASKVYNREIILRDNNRFHYIRQGKCSCGDFW 842          

Query:  184 LELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYG---SPSEAFRVFETVEDKLEVF-YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRM-QEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVS-------------------------------EALSHFCQMQSQN-MKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPD-TNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDY 2478
            L+ C +I EL      + K GL N+    TKLV+  C  G   S S A  VFE  E     F Y++L++GYA +    +A+  F RM + G+ P  Y F + L  C  +     G +IH  ++  G+A +LF   ++V+ YA+C +++ A K+FD M ER++VSW ++I GYA+   AK A++L  RM ++E   P+S+T+V ++ A A    L  G+ ++A++  +  E    + +AL+DMY KC ++  A+ +F+          N+M   YV+     EA+ +F  M+D G +P  ++++ A+ +C+ L ++  GK  H  V +    S  ++ N+L+ MY KC R D A +IF  +  KT+V+WN+++ GY +NG V                                EA+  FC MQSQ  +  D  TM+S+  A   L     AKWI+  + +     ++ + T LVDM+++CG   +A  +F+ +  R V+ W A I      G  + A++LF++M +  +KP+ + F+  ++ACSH GLV++G + F SM + +G+ P   HYG MVDLLGRAG L EA   I+ MPMEP   ++ ++L ACR   NVE+   AA+KI  L P   G +VLL+N+Y++A  W+ +AKVR  M+ KGL+K PG S + +R + H F SG  SHP+   I   L+ +       G+VPD +N + DV+   K  +L+ HSEKLA+A+GL+++  GTTI I KNLRVC DCH+  K+ S V  REII+RD +RFH+ + G CSCGD+
Sbjct:   39 LKNCKTIDELKMFHRSLTKQGLDNDVSTITKLVARSCELGTRESLSFAKEVFENSESYGTCFMYNSLIRGYASSGLCNEAILLFLRMMNSGISPDKYTFPFGLSACAKSRAKGNGIQIHGLIVKMGYAKDLFVQNSLVHFYAECGELDSARKVFDEMSERNVVSWTSMICGYARRDFAKDAVDLFFRMVRDEEVTPNSVTMVCVISACAKLEDLETGEKVYAFIRNSGIEVNDLMVSALVDMYMKCNAIDVAKRLFDEYGASNLDLCNAMASNYVRQGLTREALGVFNLMMDSGVRPDRISMLSAISSCSQLRNILWGKSCHGYVLRNGFESWDNICNALIDMYMKCHRQDTAFRIFDRMSNKTVVTWNSIVAGYVENGEVDAAWETFETMPEKNIVSWNTIISGLVQGSLFEEAIEVFCSMQSQEGVNADGVTMMSIASACGHLGALDLAKWIYYYIEKNGIQLDVRLGTTLVDMFSRCGDPESAMSIFNSLTNRDVSAWTAAIGAMAMAGNAERAIELFDDMIEQGLKPDGVAFVGALTACSHGGLVQQGKEIFYSMLKLHGVSPEDVHYGCMVDLLGRAGLLEEAVQLIEDMPMEPNDVIWNSLLAACRVQGNVEMAAYAAEKIQVLAPERTGSYVLLSNVYASAGRWNDMAKVRLSMKEKGLRKPPGTSSIQIRGKTHEFTSGDESHPEMPNIEAMLDEVSQRASHLGHVPDLSNVLMDVDEKEKIFMLSRHSEKLAMAYGLISSNKGTTIRIVKNLRVCSDCHSFAKFASKVYNREIILRDNNRFHYIRQGKCSCGDF 841          

Query:  103 PQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQ---IIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHD--VEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            P+   F+   + + +    YT P+ I  + C  + +      +   I+  G  ++      LV ++   G  + A +VF+ +  +  V +++L+ GY+ +    +A+  +  +K+  + P  +  + +L   G+   +++G+ +H   + SG  + +     +V MY K R+  +A ++FD M  RD VS+NT+I GY +  + + ++ + +   ++  KPD +T+ ++L A      L + K I+ Y+L+A F     +   L+D+Y+KCG + TAR +FN M+ K  VSWNS+I GY+Q+ D  EAM++F+ M+    Q  ++T +  +     L DL+ GK +H    +  +  D+SV N+L+ MY+KC  V  + KIF ++     V+WNT+I    + G  +  L    QM+   + PD  T +  +P  A L+  R  K IH  ++R  ++  + +  AL++MY+KCG +  + ++F+ M  R V TW  MI  YG  G G+ A++ F +MEK  I P+ + F+ +I ACSHSGLV+EGL  F  MK  Y ++P ++HY  +VDLL R+ ++S+A +FIQ MP++P  +++ ++L ACRT  ++E  ER + +I ELNP + GY +L +N Y+    WDKV+ +RK ++ K + K PG S +++   VH F SG  S PQS+ IY  LE L   +   GY+PD   +     E + K +L+  HSE+LAIAFGLLNT PGT + + KNLRVCGDCH  TK IS + GREI+VRD +RFH FK+GTCSC D W
Sbjct:   88 PEALEFYGKLRESKVSPDKYTFPSVI--KACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQF-KPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIVPDSVVFIAIIYACSHSGLVDEGLACFEKMKTHYKIDPMIEHYACVVDLLSRSQKISKAEEFIQAMPIKPDASIWASVLRACRTSGDMETAERVSRRIIELNPDDPGYSILASNAYAALRKWDKVSLIRKSLKDKHITKNPGYSWIEVGKNVHVFSSGDDSAPQSEAIYKSLEILYSLMAKEGYIPDPREVSQNLEEEEEKRRLICGHSERLAIAFGLLNTEPGTPLQVMKNLRVCGDCHEVTKLISKIVGREILVRDANRFHLFKDGTCSCKDRW 882          

Query:  184 LELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVF-YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLII---GKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFG 1887
            L   +++ EL +I  L+I  GL +   F  KL+  + ++  P+ +  VF  V     V+ ++++++ ++KN    +A+ F+ +++   V P  Y F  ++K C    D   G  ++  ++  GF ++LF   A+V+MY++   +  A ++FD MP RDLVSWN++I+GY+ +G  + ALE+   ++     PDS T+ ++LPA   +G+L++   G+ +H + L++   S+V ++  L+ MY K      AR +F+ M  + +VS+N+MI GY++ E  EE++ +F + LD+ F+P  +T+   L AC  L DL   K+++  + +     + +V N L+ +Y+KC  +  A  +F ++  K  VSWN++I GY Q+G + EA+  F  M     + D  T + +I     L+  +  K +H   I++    ++ V  AL+DMYAKCG V  + K+F  M      TWN +I      G     + +  +M K  + P+  TFL  +  C+       G +    +   +G E  +    A++++  + G L  +    ++M     +T  G
Sbjct:   14 LSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPA---FGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLR-FGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTG 580          

Query: 1393 ALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPM 1863
            AL+  S   + + IH LVI    D + F    L+D Y+      ++  +F  +   ++V  WN++I  +  NGL   A++ + ++ +  + P+  TF  VI AC+     E G   +  +  D G E  +    A+VD+  R G L+ A     +MP+
Sbjct:   13 ALSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQIL-DMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPV 169          

Query:  115 AFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            A HTLSQRTHIPSH+Y HPAAILLELCTS KE++QI+P IIKNGLYNE LFQTKL+SLFC YG+ +EA RVFE +EDK +  YHT+LKGYAK+SSL  A+SFF RMK D VRPVVYNFTYLLK+CGDN+DL+RGKEIH  +I+SGF+ NLFAMT VVNMYAKCRQIN+AY MFDRMPERDLV WNT+I+GYAQNG AK+AL LV+RM EEG +PDSIT+V++LPAVAD   L IG ++H YVLRA FESLVN+STAL+DMYSKCGSV  AR+IF+ M  +T VSWNSMIDGYVQ+ DAE AM IFQKMLDEG QPTNVT+M ALHACADLGDLERGKFVHKLVDQLKL SDVSVMNSL+SMYSKCKRVDIAA IFKNL  KTLVSWN MILGYAQNG V+EAL+ FC+MQS+N+KPDSFTMVSVIPALAELS+ RQAKWIHGLVIR   DKN+FVMTALVDMYAKCGA+HTARKLFDMM+ RHV TWNAMIDGYGT+GLGK +V+LF EM+KGTIKPNDITFLC +SACSHSGLVEEGL +F SMK+DYG+EP MDHYGAMVDLLGRAG+L++AWDFIQKMP++PGITV+GAMLGAC+ HKNV+LGE+AA +IF+LNP +GGYHVLLANIY+TAS+W KVAKVR +ME  GLQKTPGCSLV++ NEVH+FYSG+TSHPQSK+IY++LETL DEI+AAGYVPDTNSIHDVE DVK QLLN+HSEKLAIAFGLLNT+ GT IHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFH FK+G CSCGDYW
Sbjct:   24 AQHTLSQRTHIPSHIYKHPAAILLELCTSSKEVHQILPQIIKNGLYNETLFQTKLISLFCKYGNLTEASRVFEPIEDKFDALYHTMLKGYAKSSSLDSALSFFSRMKHDSVRPVVYNFTYLLKLCGDNSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPERDLVCWNTMISGYAQNGFAKVALMLVLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKMLDEGVQPTNVTVMGALHACADLGDLERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEEGLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQKMPIKPGITVYGAMLGACKIHKNVDLGEKAAFEIFKLNPDDGGYHVLLANIYATASMWGKVAKVRTIMEKSGLQKTPGCSLVEIGNEVHSFYSGTTSHPQSKKIYSYLETLVDEIRAAGYVPDTNSIHDVEDDVKVQLLNTHSEKLAIAFGLLNTSTGTPIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHLFKDGVCSCGDYW 812          

Query:  181 LLELCTSIKELN---QIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +L+L   +K L    ++   I  +G+  + +  +KLV ++   G   E   +F+ + ++    ++ ++ GY K     +++S F +M   GV    +  + +LK       ++ GK +H  L+  G  +    + +++  Y K R+++ A K+FD +  RD++SWN++I+GY  NG ++  +EL  +M   G   D  T+V++L A A+ G + +G+++H   ++A           LLDMY+KCG +  A L+F+ M  +T V+W S+I  Y +   ++EA+ +F +M  EG  P   TI   LHACA  G LE GK VH  + +  + S++ V N+LM MY+KC  ++ A  +F  +  K ++SWNTMI GY++N   +EALS F  M  + MKPD  T+  ++PA A L+   + K +HG ++R  F  +  V  ALVDMY KCG    AR LFDM+  + + TW  MI GYG +G G  A+  FNEM +  I+P++++F+ ++ ACSHSGL++EG ++F  M+++  ++P ++HY  +VDLL R+G+L+ A+ FI+ MP+EP  T++GA+L  CR H +V+L E+ A+ +FEL P   GY+VLLAN Y+ A  W++V K+R+ +  +GL+K PGCS ++++++VH F +G++SHPQ+K+I   L+ L  ++K  GY P T  ++ + ++  KE  L  HSEKLA+AFG+LN  P  TI + KNLRVCGDCH   K+IS   GREI++RD +RFHHFK+G C C  +W
Sbjct:    9 ILQLSAELKSLQDGKKVHSFICSSGISIDSVLGSKLVFMYVTCGDLREGRLIFDKIRNEKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLGVEVNSHTVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKMLYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMDREGVSPDIFTITTVLHACACNGSLENGKDVHNYIRENDMQSNIFVCNALMDMYAKCGSMEDANSVFLEMPVKDIISWNTMIGGYSKNSLPNEALSLFGDMVLE-MKPDGTTLACILPACASLASLDRGKEVHGHILRNGFFSDQQVANALVDMYVKCGVPVLARLLFDMIPTKDLITWTVMIAGYGMHGFGNNAITTFNEMRQAGIEPDEVSFISILYACSHSGLLDEGWRFFNVMQDECNVKPKLEHYACIVDLLARSGKLAMAYKFIKSMPIEPDATIWGALLSGCRIHHDVKLAEKVAEHVFELEPENTGYYVLLANTYAEAEKWEEVKKLRQKIGRRGLKKNPGCSWIEVKSKVHIFLAGNSSHPQAKKIEVLLKRLRSKMKEEGYFPKTRYALINADSLQKETALCGHSEKLAMAFGILNLPPARTIRVSKNLRVCGDCHEMAKFISKTLGREIVLRDSNRFHHFKDGVCCCRGFW 778          

Query:  757 DSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASL 2022
            +S T  ++L   A+  SL  GK +H+++  +       + + L+ MY  CG +   RLIF++++ +    WN M++GY +  D +E++ +F++MLD G +  + T+   L   A LG ++ GK+VH  + +L LGS  +V+NSL++ Y K +RVD+A K+F  L  + ++SWN+MI GY  NG   + +  F +M    +  D  TMVS++ A A        + +HG  ++ C          L+DMYAKCG +  A  +FD+M  R V TW ++I  Y   GL   A+ LF+EM++  + P+  T   V+ AC+ +G +E G      ++E+  ++  +    A++D+  + G + +A     +MP++  I+    + G  +     E      D + E+ P       +L    S ASL
Sbjct:    2 ESRTCCSILQLSAELKSLQDGKKVHSFICSSGISIDSVLGSKLVFMYVTCGDLREGRLIFDKIRNEKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLGVEVNSHTVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKMLYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMDREGVSPDIFTITTVLHACACNGSLENGKDVHNYIREN-DMQSNIFVCNALMDMYAKCGSMEDANSVFLEMPVKDIISWNTMIGGYSKNSLPNEALSLFGDMVLEMKPDGTTLACILPACASLASL 422          

Query:  181 LLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +L+ CT  K+L    Q+  +++  G  ++      LV L+   G   +A  +F+ + D+  V ++ L   Y  +   G+A+S F  M   G+RP  ++ + ++ VC    D  +G++IH +LI  G+ ++ F+  A+V+MYAK   + +A  +FD + + D+VSWN IIAG   +     ALEL+  M + G  P+  TL + L A A      +G+ +H+ +++    S   +   L+DMYSKC S+  ARL+F  M ++  ++WN++I G+ QNE+ EEA  +F  M  EG      T+   L + A L      + +H L  +     D  V+NSL+  Y KC  V+ A ++F+      LV + +++  YAQ+G+  EAL  + +MQ + +KPDSF   S++ A A LS   Q K +H  +++  F  +IF   +LV+MYAKCG++  A   F  +  R + +W+AMI G   +G GK A+ LF +M K  + PN IT + V+ AC+H+GLV E   YF SMK  +G+EP  +HY  M+DLLGRAG+L  A + + KMP +    V+GA+LGA R HKN++LGE+AA+ +  L P + G HVLLANIY++  +WDKVA+VR++M+   ++K PG S ++++++V+TF  G  SH +S  IY  L+ L D +K AGYVP     +HDVE   KEQLL  HSEKLA+AFGL+ T PG  I ++KNLR+C DCH   K+IS +  REIIVRD +RFHHF++G+CSCG+YW
Sbjct:   88 VLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFPLMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGFEFDNYVVNSLIDTYGKCGHVEDATRVFEESPTVDLVLFTSLVTAYAQDGQGEEALRLYLEMQDRGIKPDSFVCSSLLNACASLSAYEQGKQVHVHILKFGFMSDIFAGNSLVNMYAKCGSIEDASCAFSRIPVRGIVSWSAMIGGLAQHGYGKEALQLFKQMLKVGVPPNHITLVSVLCACNHAGLVAEAKHYFNSMKILFGIEPMQEHYACMIDLLGRAGKLEAAMELVNKMPFQANALVWGALLGAARIHKNIDLGEQAAEMLLALEPEKSGTHVLLANIYASVGMWDKVARVRRLMKDGKVKKEPGMSWLEVKDKVYTFIVGDRSHSRSTEIYAKLDELSDLLKKAGYVPMVEIDLHDVERSEKEQLLYHHSEKLAVAFGLIATPPGAPIRVKKNLRICFDCHTVLKFISKIVSREIIVRDTNRFHHFRDGSCSCGEYW 858          

Query:  232 IIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTH 1914
            +IK GL  +   +  LV+L+        A ++ +   +   V +  L+ GY++N    +A+  F  M   G++   + F  +LK C    DL  GK++H  ++ +GF ++ F   ++V +YAKC    +A  +FD +P+R +VSWN + + Y  + +   A+ L   M   G +P+  +L +++         + G+ IH Y+++  ++S    + AL+DMY+K G +  A  +F+ + +   VSWN++I G V +E    A+E+ ++M   G  P   T+  AL ACA +   E G+ +H  + ++ +GSD  +   L+ MYSKC  +D A  +FK +  + +++WN +I G++QN    EA S F  M ++ +  +  T+ +V+ ++A L      + IH L +++ F+ + +V+ +L+D Y KCG V  A ++F+      +  + +++  Y  +G G+ A+ L+ EM+   IKP+      +++AC+     E+G Q    + + +G    +    ++V++  + G + +A     ++P+  GI  + AM+G    H
Sbjct:    7 VIKFGLSQDPKIRNYLVNLYSKCQLFGYARKLLDRSTEPDLVSWSALISGYSQNGFCQEAVLAFYEMHLLGIKCNEFAFPSVLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFPLMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGFEFDNYVVNSLIDTYGKCGHVEDATRVFEESPTVDLVLFTSLVTAYAQDGQGEEALRLYLEMQDRGIKPDSFVCSSLLNACASLSAYEQGKQVHVHILK-FGFMSDIFAGNSLVNMYAKCGSIEDASCAFSRIPVR-GIVSWSAMIGGLAQH 565          

Query:  520 EIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHY--GAMVDLLGRAGQLSEAWDFIQKMP 1860
            EIHA +I  G + +      +VN+Y+KC+    A K+ DR  E DLVSW+ +I+GY+QNG  + A+     M   G K +     ++L A      L++GK +H  V+   F+S   ++ +L+ +Y+KCG  G AR +F+ +  ++ VSWN++   YV ++   EA+ +F  M+  G +P   ++   ++ C  L D  +G+ +H  + +L   SD    N+L+ MY+K   ++ A+ +F  +    +VSWN +I G   +     AL    +M    M P+ FT+ S + A A +++    + +H  +I+     + F+   L+DMY+KC ++  AR +F +M ER +  WNA+I G+  N   + A  LF  M    I  N  T   V+ + +         Q  A S+K  +      D+Y   +++D  G+ G + +A    ++ P
Sbjct:    2 EIHARVIKFGLSQDPKIRNYLVNLYSKCQLFGYARKLLDRSTEPDLVSWSALISGYSQNGFCQEAVLAFYEMHLLGIKCNEFAFPSVLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFPLMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGF----EFDNYVVNSLIDTYGKCGHVEDATRVFEESP 447          

Query:  112 QAFHTLSQRTHIPSHVYTHPAAILLELCTSIK--ELNQIIP-LIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLE-VFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSG-FATNLFAMTAVVNMYAKCR-QINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKC---GSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAE-EAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +A  TL Q +   +H      ++LL+ C      +L  ++   + ++GL  + +    L+SL+   G   +A  +FE++ +K + V +  L+  YA N    +A+S F  M   G  P  Y FT + + C +  ++  GK I   L+ +G F +++    A+++M+ K    +  AYK+FDRMP+R++V+W  +I  + Q G ++ A++L + M   G  PD  TL  ++ A A+ G L +G+  H  V+++  +  V +  +L+DMY+KC   GSV  AR +F+RM     +SW ++I GYVQ+   + EA+E+F +M+    +P + T    L ACA+L D+  G+ V+ LV +++L S   V NSL+SMYS+C  ++ A K F  L  K LVS+NT++  YA++    EA   F +++      ++FT  S++   + +    + + IH  ++++ F  N+ +  AL+ MY++CG +  A ++F+ M + +V +W +MI G+  +G    A++ F++M +  + PN++T++ V+SACSH GL+ EGL++F SMK ++G+ P M+HY  +VDLLGR+G L EA + +  MP +    V    LGACR H N++LG+ AA+ I E +P +   ++LL+N++++A  W++VA++RK M+ + L K  GCS +++ N+VH FY G TSHPQ++ IY  L+ L  +IK  GY+P T+ + HDVE + KEQ L  HSEK+A+A+G ++T+    I + KNLRVCGDCH A KY S+V  +EI++RD +RFHHFK+GTCSC DYW
Sbjct:  131 KAISTLDQMSLQGTHPDLITYSLLLKSCIRSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDIWLGEQVYALVVKMRLASINCVGNSLISMYSRCGNMENARKAFDVLFEKNLVSYNTIVNAYAKSLNSEEAFELFNEIEGAGTGVNAFTFASLLSGASSIGAIGKGEQIHSRILKSGFKSNLHICNALISMYSRCGNIEAAFQVFNEMGDGNVISWTSMITGFAKHGFATRALETFHKMLEAGVSPNEVTYIAVLSACSHVGLISEGLKHFKSMKVEHGIVPRMEHYACVVDLLGRSGHLEEAMELVNSMPFKADALVLRTFLGACRVHGNMDLGKHAAEIILEQDPHDPAAYILLSNLHASAGQWEEVAEIRKKMKERNLTKEAGCSWIEVENKVHKFYVGDTSHPQAQEIYDELDQLALKIKELGYIPSTDFVLHDVEEEQKEQYLFQHSEKIAVAYGFISTSTSRPIRVFKNLRVCGDCHTAFKYFSIVRRKEIVLRDANRFHHFKDGTCSCNDYW 931          

Query:  625 KMFDRMPERDLVSWNTIIAGYA--QNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRM-KQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLG---SDVSVMNSLMSMYSKCK-RVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKC---GAVHTARKLFDMMDERHVTTWNAMIDGY-GTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFA 1743
            K +    + D+ S+  ++   A  +  L K A+  + +M  +G  PD IT   LL +     +  +G  +H  + ++  E    I  +L+ +YSKCG    A  IF  M  ++  VSW+++I  Y  NE A EA+  F  ML+ GF P          AC++  ++  GK +   +  LK G   SDV V  +L+ M+ K    ++ A K+F  +  + +V+W  MI  + Q G   +A+  F  M      PD FT+  V+ A AE+ +    +  H LV+++  D ++ V  +LVDMYAKC   G+V  ARK+FD M   +V +W A+I GY  + G  + A++LF EM +G +KPN  TF  V+ AC++   +  G Q +A
Sbjct:  101 KRWKYFTKADIYSFGMLLMEMAGQRKRLNKKAISTLDQMSLQGTHPDLITYSLLLKSCIRSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFL--LKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDIWLGEQVYA 482          

Query: 1009 EEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGK-TLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRT-CFDKNIFVMTALVDMYAK-CGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRA---GQLSEAWDFIQKMPM 1863
            ++A+    +M  +G  P  +T    L +C    + + G  VH  + Q  L  D  ++NSL+S+YSKC     A +IF+++  K  LVSW+ +I  YA N +  EA+S F  M      P+ +    V  A +        K I G +++T  F+ ++ V  AL+DM+ K  G + +A K+FD M +R+V TW  MI  +   G  + AVDLF +M      P+  T   V+SAC+  GL+  G Q+   + +  GL+  +    ++VD+  +    G + +A     +MP+
Sbjct:  130 KKAISTLDQMSLQGTHPDLITYSLLLKSCIRSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKS-GLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPV 419          

Query:  145 IPSHVYTHPAAILLELCTSIKELN---QIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVF-YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLG-SDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEI-KAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +P   +T P   +L+ C  +++++   +I  LIIK G  +       LVS++        A ++F+ + ++ +V  +++++  Y+ N    +A+  F  M+  GV    Y     L+ C D++  + G EIHA ++ S    +++   A+V M+ +  +++ A ++FD + E+D ++WN++IAG+ QNGL   AL+    +Q+   KPD ++L+++L A    G L+ GK IHAY ++   +S + I   L+DMYSKC  V  A L+F++M  K  +SW ++I  Y QN    EA+++ +K+  +G     + I   L AC+ L  L   K VH     LK G SD+ + N ++ +Y+ C  ++ A ++F+++  K +VSW +MI  Y  NG  +EAL  F  M+  +++PDS T+VS++ A A LS   + K IHG + R  F      + +LVDMYA CG++  A K+F     + +  W  MI+ YG +G GKAAV+LF+ ME   + P+ ITFL ++ ACSHSGL+ EG +   +MK  Y LEP  +HY  +VDLLGRA  L EA+ F++ M +EP   V+ A LGACR H N +LGE AA K+ +L+P   G +VL++N+++ +  W  V +VR  M+  GL+K PGCS +++ N+VHTF     SHP+S +IY  L  + +++ K  GYVP T  + H+V  + K Q+L  HSE+LAIA+GL++T+ GT I I KNLRVC DCH   K +S    RE+IVRD  RFHHF++G CSCGD+W
Sbjct:   37 VPFDSFTFPC--VLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGLQDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRKVQTKGMDVDTMMIGSTLLACSGLRCLSHAKEVHGYT--LKRGLSDLMMQNMIIDVYADCGNINYATRMFESIKCKDVVSWTSMISCYVHNGLANEALGVFYLMKETSVEPDSITLVSILSAAASLSALNKGKEIHGFIFRKGFMLEGSTVNSLVDMYACCGSLENAYKVFICTRSKSLVLWTTMINAYGMHGRGKAAVELFSIMEDQKLIPDHITFLALLYACSHSGLINEGKRLLETMKCKYQLEPWPEHYACLVDLLGRANHLEEAYHFVKSMQIEPTAEVWCAFLGACRIHSNKKLGEIAAQKLLDLDPDSPGSYVLISNVFAASGRWKDVEEVRMRMKGGGLKKNPGCSWIEVGNKVHTFLVRDKSHPESYKIYQKLAQITEKLEKEGGYVPQTKLVLHNVGKEEKVQMLYGHSERLAIAYGLMSTSEGTPIRITKNLRVCVDCHTFCKLVSKFFERELIVRDASRFHHFEDGVCSCGDFW 818          

Query:  337 VEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPER-DLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASM-KEDYGLEPAMDHYGAMVDLLGRAGQLSEAW 1839
            + D+    ++ ++     N     A+  F  M+  GV    + F  +LK CG   D+ RG EIH  +I  G+ + +F   ++V+MYAKC  I  A K+FDRM ER D+VSWN+II+ Y+ NG    AL L   MQ+ G   ++ TLV  L A  D     +G  IHA +L+++    V ++ AL+ M+ + G +  A  IF+ + +K  ++WNSMI G+ QN    EA++ F  + D   +P  V+++  L A   LG L  GK +H    +  L S++ + N+L+ MYSKC  V  A  +F  ++ K L+SW T+I  YAQN   +EAL    ++Q++ M  D+  + S + A + L     AK +HG  ++     ++ +   ++D+YA CG ++ A ++F+ +  + V +W +MI  Y  NGL   A+ +F  M++ +++P+ IT + ++SA +    + +G +    + ++ + LE +     ++VD+    G L  A+
Sbjct:    1 MHDRTIFTWNAMMGANVSNGEPLRALELFREMRVLGVPFDSFTFPCVLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGLQDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRKVQTKGMDVDTMMIGSTLLACSGLRCLSHAKEVHGYTLKRGL-SDLMMQNMIIDVYADCGNINYATRMFESIKCKDVVSWTSMISCYVHNGLANEALGVFYLMKETSVEPDSITLVSILSAAASLSALNKGKEIHGFIFRKGFMLEGST--VNSLVDMYACCGSLENAY 500          

Query: 1255 KTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERH-VTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHY--GAMVDLLGRAGQLSEAWDFIQKMPMEPGIT 1878
            +T+ +WN M+     NG    AL  F +M+   +  DSFT   V+ A   +    +   IHGL+I+  +D  +FV  +LV MYAKC  +  ARKLFD M+ER+ V +WN++I  Y  NG    A+ LF EM+K  +  N  T +  + AC  S   + G++  A++ +       +D Y   A+V +  R G++S A     ++  +  IT
Sbjct:    4 RTIFTWNAMMGANVSNGEPLRALELFREMRVLGVPFDSFTFPCVLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKS---NQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNIT 211          

Query:  244 GLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGD---NADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVN--ISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEAL-HACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQN----------------MKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEM-----EKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPME-PGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            G ++       LV+++   G   +A++VF+ + ++ +V +++++    +      A+  F  M  +G  P  +    +   C +      L  GK+IH      G     F+  A++ MYAK  ++++A  +     +RDLV+WN++I+ ++QN     AL  +  M  EG KPD +T  ++LPA +    L  GK IHAY LR   + + N  + +AL+DMY  CG V + RL+F+ +  +    WN+MI GY Q+E  E+A+ +F +M       +N T M ++  A      + R + +H  V +  L ++  + N+L+ MYS+   +  + +IF ++  + +VSWNT+I  Y   GR S+AL    +MQ                    KP+S T+++V+P  A LS   + K IH   IR      + V +ALVDMYAKCG ++ AR++FD M  R+V TWN +I  YG +G GK +++LF +M     + G +KP ++TF+ + ++CSHSG+V+EGL  F  MK ++G+EPA DHY  +VDL+GRAG++ EA+  +  MP     +  + ++LGACR + N+E+GE AA+ + +L P    ++VLL+NIYS+A LWDK   +R+ M+  G++K PGCS ++  +EVH F +G  SHPQS++++ FLETL + +K  GYVPDT  + HD++ + KE +L  HSEKLAIAFG+LNT PGTTI + KNLRVC DCH A+K+IS +  REII+RD  RFHHFK+GTCSCGDYW
Sbjct:  122 GSFSSVTIDNTLVNMYGKCGGLGDAYKVFDRITERDQVSWNSIISALCRFEEWEVAIKAFRLMLMEGFEPSSFTLVSMALACSNLRKRDGLWLGKQIHGCCFRKGH-WRTFSNNALMAMYAKLGRLDDAKSLLVLFEDRDLVTWNSMISSFSQNERFMEALMFLRLMVLEGVKPDGVTFASVLPACSHLDLLRTGKEIHAYALRTD-DVIENSFVGSALVDMYCNCGQVESGRLVFDGVLDRKIGLWNAMIAGYAQSEHDEKALMLFIEMEAAAGLYSNATTMSSIVPAYVRCEGISRKEGIHGYVIKRGLETNRYLQNALIDMYSRMGDIKTSKRIFDSMEDRDIVSWNTIITSYVICGRSSDALLLLHEMQRIEEKSTYDGDYNDEKQVPFKPNSITLMTVLPGCASLSALAKGKEIHAYAIRNLLASQVTVGSALVDMYAKCGCLNLARRVFDQMPIRNVITWNVIIMAYGMHGKGKESLELFEDMVAEGAKGGEVKPTEVTFIALFASCSHSGMVDEGLSLFHKMKNEHGIEPAPDHYACIVDLVGRAGKVEEAYGLVNTMPSGFDKVGAWSSLLGACRIYHNIEIGEIAAENLLQLQPDVASHYVLLSNIYSSAGLWDKAMNLRRRMKAMGVKKEPGCSWIEYGDEVHKFLAGDLSHPQSEKLHDFLETLSERLKKEGYVPDTACVLHDIDEEEKETILCGHSEKLAIAFGILNTPPGTTIRVAKNLRVCNDCHTASKFISKIEDREIILRDARRFHHFKDGTCSCGDYW 894          

Query:  373 LKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFAT--NLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADY---GSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNS-----LMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQ-SQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEM----EKGT------------IKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTH----KNVELGE---RAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPG--CSLVDL 2103
            L+  ++++   +A+S +  M   GV P  + F  +LK      +L  GK+IHAH+   G+ +  ++     +VNMY KC  + +AYK+FDR+ ERD VSWN+II+   +    ++A++    M  EG +P S TLV++  A ++      L +GK IH    R       + + AL+ MY+K G +  A+ +    + +  V+WNSMI  + QNE   EA+   + M+ EG +P  VT    L AC+ L  L  GK +H       L +D  + NS     L+ MY  C +V+    +F  +L + +  WN MI GYAQ+    +AL  F +M+ +  +  ++ TM S++PA        + + IHG VI+   + N ++  AL+DMY++ G + T++++FD M++R + +WN +I  Y   G    A+ L +EM    EK T             KPN IT + V+  C+    + +G +  A    +  L   +    A+VD+  + G L+ A     +MP+   IT +  ++ A   H    +++EL E       K  E+ P E  +  L A+   +  + + ++   KM    G++  P     +VDL
Sbjct:   62 LRSRSRSNLFREAISTYIEMIGSGVSPDNFAFPAVLKAVAGIQELYLGKQIHAHVFKFGYGSFSSVTIDNTLVNMYGKCGGLGDAYKVFDRITERDQVSWNSIISALCRFEEWEVAIKAFRLMLMEGFEPSSFTLVSMALACSNLRKRDGLWLGKQIHGCCFRKGHWRTFS-NNALMAMYAKLGRLDDAKSLLVLFEDRDLVTWNSMISSFSQNERFMEALMFLRLMVLEGVKPDGVTFASVLPACSHLDLLRTGKEIHAYA----LRTDDVIENSFVGSALVDMYCNCGQVESGRLVFDGVLDRKIGLWNAMIAGYAQSEHDEKALMLFIEMEAAAGLYSNATTMSSIVPAYVRCEGISRKEGIHGYVIKRGLETNRYLQNALIDMYSRMGDIKTSKRIFDSMEDRDIVSWNTIITSYVICGRSSDALLLLHEMQRIEEKSTYDGDYNDEKQVPFKPNSITLMTVLPGCASLSALAKGKEIHAYAIRNL-LASQVTVGSALVDMYAKCGCLNLARRVFDQMPIRNVIT-WNVIIMAYGMHGKGKESLELFEDMVAEGAKGGEVKPTEVTFIALFASCSHSGMVDEGLSLFHKMKNEHGIEPAPDHYACIVDL 667          

Query:  661 SWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESL--VNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADL---GDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRT-CFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGT-IKPNDITFLCVISACSHSGLV--EEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQL 1827
            SW   +   +++ L + A+   I M   G  PD+     +L AVA    L +GK IHA+V +  + S   V I   L++MY KCG +G A  +F+R+ ++  VSWNS+I    + E+ E A++ F+ ML EGF+P++ T++    AC++L     L  GK +H    +       S  N+LM+MY+K  R+D A  +      + LV+WN+MI  ++QN R  EAL     M  + +KPD  T  SV+PA + L + R  K IH   +RT    +N FV +ALVDMY  CG V + R +FD + +R +  WNAMI GY  +   + A+ LF EME    +  N  T   ++ A      +  +EG+  +   +   GLE       A++D+  R G +
Sbjct:   57 SWIESLRSRSRSNLFREAISTYIEMIGSGVSPDNFAFPAVLKAVAGIQELYLGKQIHAHVFKFGYGSFSSVTIDNTLVNMYGKCGGLGDAYKVFDRITERDQVSWNSIISALCRFEEWEVAIKAFRLMLMEGFEPSSFTLVSMALACSNLRKRDGLWLGKQIHGCCFRKGHWRTFS-NNALMAMYAKLGRLDDAKSLLVLFEDRDLVTWNSMISSFSQNERFMEALMFLRLMVLEGVKPDGVTFASVLPACSHLDLLRTGKEIHAYALRTDDVIENSFVGSALVDMYCNCGQVESGRLVFDGVLDRKIGLWNAMIAGYAQSEHDEKALMLFIEMEAAAGLYSNATTMSSIVPAYVRCEGISRKEGIHGYVIKR---GLETNRYLQNALIDMYSRMGDI 450          

Query:  193 CTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKS-------DG---------VRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQ-----KPDSITLVTLLPAVADYGSLIIGKSI-HAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQ--KTAVSWNSMI 981
            C  I     I   +IK GL      Q  L+ ++   G    + R+F+++ED+  V ++T++  Y       DA+     M+        DG          +P       +L  C   + L +GKEIHA+ I +  A+ +   +A+V+MYAKC  +N A ++FD+MP R++++WN II  Y  +G  K +LEL   M  EG      KP  +T + L  + +  G +  G S+ H        E   +    ++D+  + G V  A  + N M        +W+S++
Sbjct:  412 CEGISRKEGIHGYVIKRGLETNRYLQNALIDMYSRMGDIKTSKRIFDSMEDRDIVSWNTIITSYVICGRSSDALLLLHEMQRIEEKSTYDGDYNDEKQVPFKPNSITLMTVLPGCASLSALAKGKEIHAYAIRNLLASQVTVGSALVDMYAKCGCLNLARRVFDQMPIRNVITWNVIIMAYGMHGKGKESLELFEDMVAEGAKGGEVKPTEVTFIALFASCSHSGMVDEGLSLFHKMKNEHGIEPAPDHYACIVDLVGRAGKVEEAYGLVNTMPSGFDKVGAWSSLL 698          

Query:  442 GVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYA-QNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMK-QKTAVSWNSMIDGYVQNEDAEEAMEIFQKML---DEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGS-TSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            G+ P  + F ++LK C    +   G+EIH  +      +N++  TA+V+ YAKC  +++A ++FD+M +RD+V+WN++I+G++   G       L+++MQ +   P+S T+V +LPAVA   SL  GK IH + +R  F   V + T +LD+Y KC  +  AR IF+ M   K  V+W++M+  YV  +   EA+E+F ++L   D+    + VT+   +  CA+L DL  G  +H    +     D+ V N+L+SMY+KC  ++ A + F  +  +  VS+  +I GY QNG   E L  F +MQ   + P+  T+ SV+PA A L+        H   I   F  +  +  AL+DMYAKCG + TARK+FD M +R + +WN MI  YG +G+G  A+ LF+ M+   +KP+D+TF+C+ISACSHSGLV EG  +F +M +D+G+ P M+HY  MVDLL RAG   E   FI+KMP+EP + V+GA+L ACR +KNVELGE  + KI +L P   G  VLL+N+YS    WD  A+VR   + +G +K+PGCS +++   VHTF  G   SHPQ  +I   L+ L  E+K  GY  +++ +  DVE + KE++L  HSEKLAIAFG+L+ +P   I + KNLRVCGDCH A K+ISLVT R+I VRD  RFHHFK+G C+CGD+W
Sbjct:    5 GITPNRFTFPFVLKACSALKEASEGREIHCDIKRLRLESNVYVSTALVDFYAKCGCLDDAKEVFDKMHKRDVVAWNSMISGFSLHEGSYDEVARLLVQMQND-VSPNSSTIVGVLPAVAQVNSLRHGKEIHGFCVRRGFVGDVVVGTGILDVYGKCQCIDYARRIFDMMGIVKNEVTWSAMVGAYVVCDFMREALELFCQLLMLKDDVIVLSAVTLATVIRVCANLTDLSTGTCLHCYAIKSGFVLDLMVGNTLLSMYAKCGIINGAMRFFNEMDLRDAVSFTAIISGYVQNGNSEEGLRMFLEMQLSGINPEKATLASVLPACAHLAGLHYGSCSHCYAIICGFTADTMICNALIDMYAKCGKIDTARKVFDRMHKRGIVSWNTMIIAYGIHGIGLEALLLFDNMQSEGLKPDDVTFICLISACSHSGLVAEGKYWFNAMTQDFGIIPRMEHYACMVDLLSRAGLFKEVHSFIEKMPLEPDVRVWGALLSACRVYKNVELGEGVSKKIQKLGPESTGNFVLLSNMYSAVGRWDDAAQVRFTQKEQGFEKSPGCSWIEISGVVHTFLGGGYRSHPQLTQISNKLDELLVEMKRLGYQAESSYVFQDVEEEEKERVLLYHSEKLAIAFGILSLSPDKHIIVTKNLRVCGDCHTAIKFISLVTKRDITVRDASRFHHFKDGICNCGDFW 690          

Query:  160 YTHPAAILLELCTSIKELNQ-------IIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMP-ERDLVSWNTIIAGYAQNGLAKIALEL---VIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAK-WIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMI 1587
            +T P   +L+ C+++KE ++       I  L +++ +Y      T LV  +   G   +A  VF+ +  +  V +++++ G++ +    D ++       + V P       +L        LR GKEIH   +  GF  ++   T ++++Y KC+ I+ A ++FD M   ++ V+W+ ++  Y      + ALEL   ++ ++++     ++TL T++   A+   L  G  +H Y +++ F   + +   LL MY+KCG +  A   FN M  + AVS+ ++I GYVQN ++EE + +F +M   G  P   T+   L ACA L  L  G   H         +D  + N+L+ MY+KC ++D A K+F  +  + +VSWNTMI+ Y  +G   EAL  F  MQS+ +KPD  T + +I A +   +  + K W + +         +     +VD+ ++ G         + M  E  V  W A++
Sbjct:   11 FTFP--FVLKACSALKEASEGREIHCDIKRLRLESNVY----VSTALVDFYAKCGCLDDAKEVFDKMHKRDVVAWNSMISGFSLHEGSYDEVARLLVQMQNDVSPNSSTIVGVLPAVAQVNSLRHGKEIHGFCVRRGFVGDVVVGTGILDVYGKCQCIDYARRIFDMMGIVKNEVTWSAMVGAYVVCDFMREALELFCQLLMLKDDVIVLSAVTLATVIRVCANLTDLSTGTCLHCYAIKSGFVLDLMVGNTLLSMYAKCGIINGAMRFFNEMDLRDAVSFTAIISGYVQNGNSEEGLRMFLEMQLSGINPEKATLASVLPACAHLAGLHYGSCSHCYAIICGFTADTMICNALIDMYAKCGKIDTARKVFDRMHKRGIVSWNTMIIAYGIHGIGLEALLLFDNMQSEGLKPDDVTFICLISACSHSGLVAEGKYWFNAMTQDFGIIPRMEHYACMVDLLSRAGLFKEVHSFIEKMPLEPDVRVWGALL 493          

Query: 1036 MLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYA-QNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDGYGTNGLGKAAVDLFNE---MEKGTIKPNDITFLCVISACSHSGLVEEG-LQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGER 1938
            ML  G  P   T    L AC+ L +   G+ +H  + +L+L S+V V  +L+  Y+KC  +D A ++F  +  + +V+WN+MI G++   G   E      QMQ+ ++ P+S T+V V+PA+A+++  R  K IHG  +R  F  ++ V T ++D+Y KC  +  AR++FDMM   ++  TW+AM+  Y      + A++LF +   ++   I  + +T   VI  C++   +  G   +  ++K  + L+  + +   ++ +  + G ++ A  F  +M +   ++ F A++     + N E G R
Sbjct:    1 MLGYGITPNRFTFPFVLKACSALKEASEGREIHCDIKRLRLESNVYVSTALVDFYAKCGCLDDAKEVFDKMHKRDVVAWNSMISGFSLHEGSYDEVARLLVQMQN-DVSPNSSTIVGVLPAVAQVNSLRHGKEIHGFCVRRGFVGDVVVGTGILDVYGKCQCIDYARRIFDMMGIVKNEVTWSAMVGAYVVCDFMREALELFCQLLMLKDDVIVLSAVTLATVIRVCANLTDLSTGTCLHCYAIKSGFVLDLMVGN--TLLSMYAKCGIINGAMRFFNEMDLRDAVS-FTAIISGYVQNGNSEEGLR 303          

Query:  193 CTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVF------------YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRV-------------------------------SEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPD-TNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            C ++ EL Q+   I KNGL +  L  T L+S     G+    F   E  +  LE+F            + +L++G++       A+  F ++   G  P  + F ++L  C  +A L  G ++H  ++  GF  ++F   ++++ Y +C +I+   ++FD+M ER++VSW ++I GYA+ G  K A+ L   M E G +P+S+T+V ++ A A    L +G+ +   +     E    +  AL+DMY KCG++  AR IF+    K  V +N+++  YV+   A E + +  +ML  G +P  +T++ A+ AC++L D+  GK+ H  V +  L    +V N++++MY KC + ++A ++F  +L KT VSWN++I G+ +NG +                                EA+  F  MQS+ +  D  TMV V  A   L     AKWIHG + +     ++ + TALVDM+A+CG   +A ++F+ M +R V+ W A I      G G  A++LF+EM +  IKP+ + F+ +++A SH GLVE+G   F SMK+ YG+ P   HYG MVDLLGRAG LSEA   I  M MEP   ++G++L ACR HKNV++   AA++I EL+P   G HVLL+NIY++A  WD VAKVR  ++ KG  K PG S +++  ++  F +G  SHP+   I   L+ +   ++  GYVPD TN + DV    KE LL+ HSEKLAIAF L++T  G  I + KNLR+C DCH+  K +S    REIIVRD +RFH F+ G CSCGDYW
Sbjct:   43 CKTMTELKQLHSQITKNGLNHHPLSLTNLISSCTEMGT----FESLEYAQKALELFIEDNGIMGTHYMFSSLIRGFSACGLGYKAIVVFRQLMCMGAVPDNFTFPFVLSACTKSAALTEGFQVHGAIVKMGFERDMFVENSLIHFYGECGEIDCMRRVFDKMSERNVVSWTSLIGGYAKRGCYKEAVSLFFEMVEVGIRPNSVTMVGVISACAKLQDLQLGEQVCTCIGELELEVNALMVNALVDMYMKCGAIDKARKIFDECVDKNLVLYNTIMSNYVRQGLAREVLAVLGEMLKHGPRPDRITMLSAVSACSELDDVSCGKWCHGYVLRNGLEGWDNVCNAIINMYMKCGKQEMACRVFDRMLNKTRVSWNSLIAGFVRNGDMESAWKIFSAMPDSDLVSWNTMIGALVQESMFKEAIELFRVMQSEGITADKVTMVGVASACGYLGALDLAKWIHGYIKKKDIHFDMHLGTALVDMFARCGDPQSAMQVFNKMVKRDVSAWTAAIGAMAMEGNGTGAIELFDEMLQQGIKPDGVVFVALLTALSHGGLVEQGWHIFRSMKDIYGIAPQAVHYGCMVDLLGRAGLLSEALSLINSMQMEPNDVIWGSLLAACRVHKNVDIAAYAAERISELDPERTGIHVLLSNIYASAGRWDDVAKVRLHLKEKGAHKMPGSSSIEINGKIFEFTTGDESHPEMTHIEPMLKEICCRLRDIGYVPDLTNVLLDVNEKEKEYLLSRHSEKLAIAFALISTGQGMPIRVAKNLRICSDCHSFAKLVSKSYSREIIVRDNNRFHFFQQGFCSCGDYW 845          

Query:  181 LLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKS-DGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVM-NSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQS-QNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPD-TNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLR 2355
            L + CT ++++     L++ +G + ++   +K+V+L+  +G  S A+  F  + +K    ++++   Y  +    +A+  F +  S  G+RP  Y F  ++K CGD  D   GK+IH  ++  GF  ++F   ++V+MY++   + +A K+FD MP RD  SWN +I+GY QNG A  AL++   M+ EG K D+IT+ ++LP  A  G ++ GK IH YV++   E  + +S AL++MY+K GS+G A+ +F +M  +  VSWNS+I  Y QN +   A   F KM +   QP  +T++      A L D +  + VH  V +     +  ++ N+++ MY+K   +D A  +F  LL K +VSWNT+I GYAQNG  SEA+  +  M+  + + P+  T VS++PA + +   +Q   IHG VI+ C   ++FV T L+DMY KCG +  A  LF  +  ++   WNAMI  YG +G G+ A++LF EM+   +KP+ ITF+ ++SACSHSGLV +    F  M+E+YG++P++ HYG MVDL GRAG+L  A++FI+KMP++P  + +GA+L ACR H N+ELG+ A++++FE++    GY+VLL+NIY+    W+ V  VR +   +GL+K PG S + L N+V  FY+G+ +HP+ + IY  L  L  +IK  GYVPD    + DVE D KE +L  HSE+LAIA+G+++T+P T I I KNLR
Sbjct:    8 LFKSCTKLQQVKCAHTLVVVSGRFKDNFLSSKIVNLYSQHGDVSLAWWTFHHLPNKDVYTWNSMAFAYVSHGRFCEALGCFNQFFSTSGLRPDFYTFPPVVKACGDLLD---GKKIHCLVLKLGFEWDVFVAASLVHMYSRFGLVGDARKLFDDMPARDRGSWNAMISGYCQNGNAAEALDIADEMRLEGVKMDAITVASVLPVCAQVGDILSGKLIHLYVIKHGLEFELFVSNALINMYAKFGSLGHAQKVFGQMVVRDIVSWNSIIAAYEQNNNPVSAHLFFHKMQEARVQPDLLTLVSLASIVAQLNDHQNSRSVHGFVMRKGWFMEYIIIGNAVVDMYAKIGNLDSARAVFGGLLIKDVVSWNTLITGYAQNGLASEAIEVYLLMEEHEEIIPNQGTWVSILPAYSHVGALQQGMRIHGQVIKNCLYSDVFVGTCLIDMYGKCGKLDDAISLFYQVPRKNSVPWNAMISCYGVHGDGEKALELFREMKAERVKPDHITFVSLLSACSHSGLVSDAQWCFNMMEEEYGIKPSLKHYGCMVDLFGRAGELEMAFNFIKKMPIQPDASAWGALLNACRIHGNIELGKHASERLFEVDSENVGYYVLLSNIYANVGKWEGVDDVRSLARDRGLRKNPGWSSIILNNKVDVFYTGNQTHPKCEEIYRELRDLTSKIKTIGYVPDFCFVLQDVEEDEKEHILMGHSERLAIAYGIISTSPKTPIRIFKNLR 733          

Query:  277 LVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGD 2475
            L+S+F  +G    A+ VF  + ++    ++ L+ GY K     +A+  + R+   G+RP VY F  +L+ C    DL RG+E+HAH++   F  ++  + A++ MY KC  +  A  +FD+MP RD +SWN +I+GY +N      LEL  RM+E    PD +T+ +++ A    G   +G  +H+YV+R +++  +++  +L+ MY   G    A  +F+ M+ +  VSW ++I G V N   ++A+E ++ M   G  P  VTI   L ACA LG L+ G  +H+L ++      V V NSL+ MYSKCKR++ A +IF  +  K ++SW ++I G   N R  EAL  F +M  ++ KP+S T++S + A A +      K IH   ++     + F+  A++D+Y +CG + TA   F++ +E+ V  WN ++ GY   G G   ++LF  M +  I P+D+TF+ ++ ACS SG+V EGL+YF  MK +Y + P + HY  +VDLLGRAG+L+EA +FI++MP++P   ++GA+L ACR H++V LGE AA  IF+ +    GY++LL N+Y+ +  WD+VAKVR+ M+ +GL   PGCS V+++ +VH F SG   HPQ + I   LE   +++K +G+     S  D     K  +   HSE+ AIA+ L+N+ PG  I + KNL +C  CH+  K+IS +  REI VRD  +FHHFK+G CSCGD
Sbjct:   52 LLSMFVRFGDVGNAWNVFGRMGERDLFSWNVLVGGYTKAGFFDEALCLYHRILWAGIRPDVYTFPSVLRSCAGAMDLVRGREVHAHVVRFDFDMDVDVVNALITMYVKCGDVVSARMLFDKMPTRDRISWNAMISGYFENDECLEGLELFFRMRELSIDPDLMTMTSVISACELLGDERLGTQLHSYVVRTAYDGNISVYNSLIQMYLSVGHWKEAESVFSGMECRDVVSWTTIISGCVDNLLPDKALETYKTMEITGTMPDEVTIASVLSACASLGQLDMGMKLHELAERTGHILYVVVANSLIDMYSKCKRIEKALEIFHQIPDKDVISWTSVINGLRINNRCFEALIFFRKMILKS-KPNSVTLISALSACARVGALMCGKEIHAHALKAGMGFDGFLPNAILDLYVRCGRMRTALNQFNL-NEKDVGAWNILLTGYAQKGKGAMVMELFKRMVESEINPDDVTFISLLCACSRSGMVTEGLEYFQRMKVNYHITPNLKHYACVVDLLGRAGKLNEAHEFIERMPIKPDPAIWGALLNACRIHRHVLLGELAAQHIFKQDAESIGYYILLCNLYADSGKWDEVAKVRRTMKEEGLIVDPGCSWVEVKGKVHAFLSGDNFHPQMQEINVVLEGFYEKMKTSGFNGQECSSMDGIQTSKADIFCGHSERQAIAYSLINSAPGMPIWVTKNLYMCQSCHSTVKFISKIVRREISVRDTEQFHHFKDGLCSCGD 782          

Query:  466 FTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAM---TAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGQLSEA 1836
            F  L+++C +      G+ +   ++SS     L ++    A+++M+ +   +  A+ +F RM ERDL SWN ++ GY + G    AL L  R+   G +PD  T  ++L + A    L+ G+ +HA+V+R  F+  V++  AL+ MY KCG V +AR++F++M  +  +SWN+MI GY +N++  E +E+F +M +    P  +T+   + AC  LGD   G  +H  V +     ++SV NSL+ MY        A  +F  +  + +VSW T+I G   N    +AL  +  M+     PD  T+ SV+ A A L        +H L  RT     + V  +L+DMY+KC  +  A ++F  + ++ V +W ++I+G   N     A+  F +M   + KPN +T +  +SAC+  G +  G +  A ++K   G +  + +  A++DL  R G++  A
Sbjct:   13 FVALIRLCENKRGYSEGEYVWKAVLSS--LVTLLSVRLGNALLSMFVRFGDVGNAWNVFGRMGERDLFSWNVLVGGYTKAGFFDEALCLYHRILWAGIRPDVYTFPSVLRSCAGAMDLVRGREVHAHVVRFDFDMDVDVVNALITMYVKCGDVVSARMLFDKMPTRDRISWNAMISGYFENDECLEGLELFFRMRELSIDPDLMTMTSVISACELLGDERLGTQLHSYVVRTAYDGNISVYNSLIQMYLSVGHWKEAESVFSGMECRDVVSWTTIISGCVDNLLPDKALETYKTMEITGTMPDEVTIASVLSACASLGQLDMGMKLHELAERTGHILYVVVANSLIDMYSKCKRIEKALEIFHQIPDKDVISWTSVINGLRINNRCFEALIFFRKMILKS-KPNSVTLISALSACARVGALMCGKEIHAHALKAGMGFDGFLPN--AILDLYVRCGRMRTA 468          

Query:    1 MSSQLLHYTALLPITNSIXXXXXXXXXXXXX-----ISAPQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            MSSQLL +  L PITN+I                  I+ P+ Q FHTLSQRTHIPSHVY HPAAILLELCTS +ELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYG P+EA RVF+TVEDKLEVFYHTLLKGYAKNSSLGDA SFFCRMK DGV+PVVYNFTYLLKVCGDNADLRRGKEIH  LISSGFA+NLFAMTAVVN+YAKCRQ++EAYKMFDRMPERDLVSWNTI+AGYAQNGLAKIA+ELVIRMQEEGQKPD ITLVTLLPAVAD+GSLIIGKSIHAYV+RA FES VN+STAL+DMYSKCGSVGTARLIF RMK KT VSWNSMIDGYVQNED +EAME+FQKMLD+GF+PTNVTIMEALHACADLGDLERG FVHKL+DQ+KLGSDVSVMNSL+SMYSKCKRVDIAAKIF  L GKT VSWN MILGYAQNGRVSEALSHF +M SQN+KPDSFTMVSVIPA+AELSVTRQAKWIHGLVIR CFDKN+FVMTALVDMYAKCGAVH+ARKLFDMMDERHVTTWNAMIDGYGTNGLGK+AVDLFNEM+KGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAG+L EAWDFIQ MPMEPGITVFGAMLGACR HKN+ELGE+AADKIF+LNP +GGYHVLLANIY TASLWDKVA VR MME KGLQKTPGCSLVDL+NEVHTFYSGSTSHPQSKRIY+FL+TLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPG TIHIRKNLRVCGDCHNATKYISLVT REIIVRDMHRFHHFKNGTCSCGDYW
Sbjct:    1 MSSQLLSFIPLHPITNTITPPLPPPPPPTPSRLRPPIATPKSQTFHTLSQRTHIPSHVYKHPAAILLELCTSXQELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHSARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGRLYEAWDFIQNMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFKLNPADGGYHVLLANIYQTASLWDKVANVRTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSKRIYSFLDTLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGATIHIRKNLRVCGDCHNATKYISLVTRREIIVRDMHRFHHFKNGTCSCGDYW 832          

Query:    1 MSSQLLHYTALLPITNSIXXXXXXXXXXXXX-----ISAPQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            MSSQLL +  L PITN+I                  I+ P+ Q FHTLSQRTHIPSHVY HPAAILLELCTS +ELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYG P+EA RVF+TVEDKLEVFYHTLLKGYAKNSSLGDA SFFCRMK DGV+PVVYNFTYLLKVCGDNADLRRGKEIH  LISSGFA+NLFAMTAVVN+YAKCRQ++EAYKMFDRMPERDLVSWNTI+AGYAQNGLAKIA+ELVIRMQEEGQKPD ITLVTLLPAVAD+GSLIIGKSIHAYV+RA FES VN+STAL+DMYSKCGSVGTARLIF RMK KT VSWNSMIDGYVQNED +EAME+FQKMLD+GF+PTNVTIMEALHACADLGDLERG FVHKL+DQ+KLGSDVSVMNSL+SMYSKCKRVDIAAKIF  L GKT VSWN MILGYAQNGRVSEALSHF +M SQN+KPDSFTMVSVIPA+AELSVTRQAKWIHGLVIR CFDKN+FVMTALVDMYAKCGAVH ARKLFDMMDERHVTTWNAMIDGYGTNGLGK AV LFNEM+KG IKPNDITFLCVISACSHSGLVEEGLQYFAS KEDYGLEPAMDHYGAMVDLLGRAG+L EAWDFIQ MPMEPGITVFGAMLGACR HKN+ELGE+AADKIF LNP +GGYHVLLANIY TASLWDKVA V  MME KGLQKTPGCSLVDL+NEVHTFYSGSTSHPQSKRIY FL+TLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPG TIHIRKNLRVCGDCHNATKYISLVT REIIVRDMHRFHHFKNGTCSCGDYW
Sbjct:    1 MSSQLLSFIPLHPITNTITPPLPPPPPPTPSRLRPPIATPKSQTFHTLSQRTHIPSHVYKHPAAILLELCTSXQELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKXAVXLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQNMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFXLNPADGGYHVLLANIYQTASLWDKVAXVXTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSKRIYXFLDTLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGATIHIRKNLRVCGDCHNATKYISLVTRREIIVRDMHRFHHFKNGTCSCGDYW 832          

Query:  190 LCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            LCTS++ELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYG P+EA RVF+TVEDKLEVFYHTLLKGYAKNSSLGDA SFFCRMK DGV+PVVYNFTYLLKVCGDNADLRRGKEIH  LISSGFA+NLFAMTAVVN+YAKCRQ++EAYKMFDRMPERDLVSWNTI+AGYAQNGLAKIA+ELVIRMQEEGQKPD ITLVTLLPAVAD+GSLIIGKSIHAYV+RA FES VN+STAL+DMYSKCGSVGTARLIF RMK KT VSWNSMIDGYVQNED +EAME+FQKMLD+GF+PTNVTIMEALHACADLGDLERG FVHKL+DQ+KLGSDVSVMNSL+SMYSKCKRVDIAAKIF  L GKT VSWN MILGYAQNGRVSEALSHF +M SQN+KPDSFTMVSVIPA+AELSVTRQAKWIHGLVIR CFDKN+FVMTALVDMYAKCGAVH ARKLFDMMDERHVTTWNAMIDGYGTNGLGK+AVDLFNEM+KG IKPNDITFLCVISACSHSGLVEEGLQYFAS KEDYGLEPAMDHYGAMVDLLGRAG+L EAWDFIQ MPMEPGITVFGAMLGACR HKN+ELGE+AADKIF LNP +GGYHVLLANIY TASLWDKVA V  MME KGLQKTPGCSLVDL+NEVHTFYSGSTSHPQSKRIY FL+TLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPG TIHIRKNLRVCGDCHNATKYISLVT REIIVRDMHRFHHFKNGTCSCGDYW
Sbjct:  229 LCTSMQELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQNMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFXLNPADGGYHVLLANIYQTASLWDKVAXVXTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSKRIYXFLDTLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGATIHIRKNLRVCGDCHNATKYISLVTRREIIVRDMHRFHHFKNGTCSCGDYW 992          

Query:  112 QAFHTLSQRTHIPSHVYTHPAA-----ILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMK-SDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLK-LGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQS-QNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            Q+F + +    +PS  + +         L   CT++    Q+   ++  G         KLV+ +   G  S + R F+++  K    +++++  Y ++    +A+  F +   +  + P  Y F  +LK C +  D   GK+IH  ++  GF  ++F   ++++MY++   I  A K+FD MP RD  SWN +I+G+ QN  A  AL++++ M+ EG K D +T+ +LL A A    +  G+ IH YV++   +  + +  AL++MYSK GS+G AR +F++M+ +  VSWNS++  Y QN D   A+E+F  M   G QP  +T++      A L D E+ K VH  + +      DV + N+++ MY+K   +D A  +F+ L  K  VSWNT+I GYAQNG  SEA+  +  MQ  + + P+  T VS++PA   +   +Q   +HG VI+     ++FV T L+DMY KCG +  A  LF  +  +    WNA+I  +G +G G+ A+ LFN+M    +KP+ +TF+ +++ACSHSGLV EG  +F +M+E YG++P++ HYG MVDLLGRAG L++A+ FI+ M + P  +V+GA+LGACR H NVE+G+ A++++FE++    GY+VLL+NIY+    W+ V KVR +   +GL KTPG S +++ N V  FY+ + SHP+ + IY  L  L   +K+ GY+PD + +  DVE D KE +LNSHSE+LAIAFG+++T P T I I KNLRVCGDCHNATK+IS++T REIIVRD +RFHHFK+GTCSCGDYW
Sbjct:   48 QSFSSTTNTLQLPSDGFANDNRNDNIDFLFHSCTNVHHAKQLHAYLVVLGKSQNIFLAAKLVNRYAYLGDLSFSRRTFDSIPRKDVYTWNSMVSAYVRSGRFREALDCFSQFSLTSDLHPDFYTFPPVLKACENLVD---GKKIHCRVLKLGFEWDVFVAASLIHMYSRFGFIYVARKLFDDMPIRDTGSWNAMISGFCQNANAADALDVLVEMRMEGIKMDRVTVASLLTACAQSNDISSGRLIHLYVIKHGLDFDLFVCNALINMYSKFGSLGHARRVFDQMEVRDLVSWNSIVAAYEQNNDPITALELFNAMQLRGIQPDFLTLVSLASILAQLSDSEKSKSVHGFILRRDWFVEDVVIGNAVVDMYAKLGAIDSARTVFEGLPTKDAVSWNTLITGYAQNGHASEAIEVYRMMQQCKEIIPNHGTWVSILPAYTHVGALQQGMKVHGRVIKNRVYSDVFVGTCLIDMYGKCGRLDDALCLFSQVPRKSSVPWNALISCHGVHGHGEKALQLFNDMLDEGVKPDHVTFVSLMAACSHSGLVNEGQSFFHTMQEQYGIKPSLKHYGCMVDLLGRAGHLNKAYSFIENMSVRPDASVWGALLGACRIHGNVEMGKIASERLFEVDSENVGYYVLLSNIYANFGKWEGVEKVRSLARNRGLTKTPGWSSIEVNNNVDVFYTANQSHPKCEEIYEKLRDLTARMKSLGYIPDLSFVLQDVEDDEKEHILNSHSERLAIAFGIISTAPKTPIRIFKNLRVCGDCHNATKFISVITEREIIVRDSNRFHHFKDGTCSCGDYW 843          

Query:  181 LLELCTSIKELNQ---IIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            ++ELC  +  L     +  +I  NG+  +     KLV ++   G   EA RVF+ + +     ++ ++  YAK  +  + +  F +M+  G++   Y F+ +LK       +R G+ IH +L   GF ++     +++  Y K R+I  A K+FD + +RD++SWN++I+ Y  NGLA+  +E+  +M   G   D  T++ +L A    G+L +G+++HAY ++ASF+  V     +LDMYSKCG + +A  +F +M +++ VSW SMI G+++   ++EA+ +F +M  +G  P   TI   LHACA  G L++G+ +H  + +  + S + V N+LM MY+KC  ++ A  +F  +  K +VSWNTMI GY++N   +EAL  F +M  Q  KPDS T+ SV+PA A L+   + + IHG ++R  +     V  ALVDMY KCG +  AR LFD +  + + +W  +  GYG +G G+ A+  FNEM K  I+P+ ++F+ ++ ACSHSGL +E  ++F +M+ DYG+ P ++HY  MVDLL R G L++A+ FI+ MP+EP  T++G++L  CR H +V+L E+ A+ +FEL P   GY+VLLANIY+ A  W++V  +R+ +  +GL+K PGCS ++++ +V  F +G +SHPQ+ +I + L+ L  ++K  G  P    ++ + +   KE  L  HSEKLAIAFG+LN  PG TI + KNLRVCGDCH   K+IS  + REI++RD +RFHH K+G CSC  +W
Sbjct:  550 VVELCAGMMSLQDGKXVHSVICDNGVEADGQLGAKLVFMYVKCGDLREARRVFDKLSNGKVFVWNLMINEYAKVRNFREGVYLFGKMQELGIQANSYTFSCVLKCFSALGCVREGEWIHGYLYKLGFGSDNTVGNSLMAFYFKNRRIEXARKVFDELCDRDVISWNSMISAYVSNGLAEKGVEIFRQMVSLGIDVDLATIINVLMACVAGGNLSLGRALHAYAIKASFDEDVMFCNNVLDMYSKCGDLSSAIQVFKKMGERSVVSWTSMIAGHIREGLSDEAIGLFSEMERDGVNPDAYTITSILHACASSGSLKKGRDIHNYIKEHGMDSSLYVCNTLMDMYAKCGSMEDAHSVFSRMPAKDIVSWNTMIGGYSKNCLPNEALKLFSEMM-QKSKPDSMTIASVLPACASLAALNRGQEIHGHILRNGYFSERHVANALVDMYVKCGVLVLARLLFDXIPVKDLISWTVIXAGYGMHGFGREAIAAFNEMRKAGIEPDSVSFISILYACSHSGLXDEAWRFFDTMRNDYGIVPKLEHYACMVDLLSRTGNLTKAYKFIKTMPIEPDATIWGSLLCGCRIHHDVKLAEKVAEHVFELEPENTGYYVLLANIYAEAEKWEEVKMLRERITRRGLKKNPGCSWIEIKGKVKIFVAGDSSHPQAAKIESLLKRLRLKMKEEGQSPKMQYALINADEAEKEVALCGHSEKLAIAFGILNLQPGKTIRVTKNLRVCGDCHEMAKFISRTSRREIVLRDSNRFHHMKDGNCSCRGFW 1319          

Query: 1273 NTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEG 1728
            N  I  Y + G +  A+      Q   +  +++   SV+   A +   +  K +H ++     + +  +   LV MY KCG +  AR++FD +    V  WN MI+ Y      +  V LF +M++  I+ N  TF CV+   S  G V EG
Sbjct:  515 NAKINKYCEMGNLKSAMEMVSGAQKSELDLEAYC--SVVELCAGMMSLQDGKXVHSVICDNGVEADGQLGAKLVFMYVKCGDLREARRVFDKLSNGKVFVWNLMINEYAKVRNFREGVYLFGKMQELGIQANSYTFSCVLKCFSALGCVREG 664          

Query:  181 LLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDT-NSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            LL   T +  L Q    II NG  N+    TKL   F +  +   A  +F ++       ++ +++G+A N++   A+S +  + K+  ++P  + + + +       D + G  +HAH I  G  +NL+  + VV+ Y    ++  A K+FD MPE+D + WNT+I+G  +N     ++++   M   G   DS TL T+LPAVA+   L  G  +H   L+A + S V++ T L+ +YSKC  + TARL+F  + Q   + +N+MI GY  N + E ++ +F+ +L  G +  + TI+  +   +  G L     +     +  + S  SV  + +++Y +   +++A ++F     KTL SWN MI GY QNG    A+S F +M S+   P+  T+ S++ A A+L      KW HGL+     + NI+V+T+LVDMYAKCG++  ARKLFD M E++V TWNAMI  YG +G G  A+ LF EM    I P+ +TFL V+ ACSH+GLV EG +    M  ++G EP  +HY  MVD+LGRAG+L +A +FI++MP+EPG  V+GA+LGAC  HKN EL   A++ +FEL+P   GY+VLL+N+YS    + K A VR++++ + L KTPGC+LV++    H F     SHPQ+  IY  L+ L  ++  AG+  +T  ++HDVE + KE ++  HSEKLAIAF L+ T PG  I I KNLRVC DCHNATK+IS +T R I+VRD +RFHHFK+G CSCGDYW
Sbjct:   22 LLNNATCLSHLTQTHAQIILNGYQNDLATVTKLTHKFSDLKAMRNARDLFLSIPRPDLFLFNVVIRGFAANAAPYSAISLYTHLRKNTNLKPDKFTYAFAVSAXSGFKDEKYGILLHAHSIVDGLGSNLYVGSIVVDFYFTVSRVELAQKVFDGMPEKDTILWNTMISGLVRNCYYADSMQVFGDMVGGGMGFDSTTLATVLPAVAELQELKAGMRVHCLALKAGYHSDVHVLTGLVSLYSKCKELETARLLFGHISQPDLICYNAMIAGYTCNNETESSVSLFRDLLASGEKVNSSTIVGLIPVSSPFGHLHLTGSLQTFCVKSGIVSHPSVSTAFVTVYCRLNEIELARQLFDQSKEKTLASWNAMISGYTQNGLTETAISLFREMMSE-FSPNPVTVTSILSACAQLGAISLGKWXHGLIKSKNLESNIYVLTSLVDMYAKCGSIVEARKLFDSMTEKNVVTWNAMISAYGLHGDGHEALKLFTEMLHSGISPSAVTFLSVLYACSHAGLVREGEEILDHMVHNHGFEPLPEHYACMVDILGRAGKLEKALEFIKEMPVEPGPPVWGALLGACMIHKNTELARVASENLFELDPDNTGYYVLLSNVYSADRNFPKAASVRQVVKNRNLAKTPGCTLVEIGETPHVFTCXDRSHPQATAIYRMLDELXGKMAEAGFQTETVTALHDVEEEEKELMMKVHSEKLAIAFALIETAPGXEIRIFKNLRVCLDCHNATKFISKITERVIVVRDANRFHHFKDGICSCGDYW 789          

Query:  277 LVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGY-VPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGD--YW 2481
            L+S+F  +G+  +A+ VF  + ++    ++ L+ GYAK     +A++ + RM   G+ P +Y F  +L+ CG   DL RG+EIH H+I  GF +++  + A++ MY KC  +  A K+FD+MP RD +SWN +I+GY +NG     L+L + M+E    PD +T+ +L+ A    G   +G+ IH Y+LR  F   V++  +L+ MYS  G    A  +F+RM+ K  VSW SMI  Y  N   ++A+E ++ M  EG  P  +TI   L ACA LG+L+ G  +H+L  +    S V V N+L+ MYSKCK VD A ++F  +  K ++SW+++ILG   N R  EAL  F QM+ + +KP+S T+VSV+ A A +      K IH   +RT    +  +  AL+D+Y +CG +  A   F+  +++ V  WN ++ GY   G GK AV+LF+ M +  + P++ITF+ ++ ACS SG+V EGL+YF SMK +Y + P + HY  +VDLLGR GQL  A +FIQKMP+ P   ++GA+L AC  +K VELGE AA++IF+++    GY+VL+ N+Y+ +  W++VA VRKMM  +GL   PGCS V+++ +VH F SG   HPQ K I   ++   +++++AG   P+T    + EA  K ++   HSE+LA+AFGL+NT PG  I + KNL +C  CH+  K+IS V  REI VRD  +FHHFK+G+C+CGD  YW
Sbjct:  135 LLSMFVRFGNLVDAWYVFGRMGERDVFSWNVLVGGYAKAGFFDEALNLYHRMLWVGIVPDIYTFPCVLRTCGGVPDLARGREIHLHVIRFGFESDVDVVNALITMYVKCGALGTARKLFDKMPRRDRISWNAMISGYFENGEFLEGLKLFLMMRESSIYPDLMTMTSLVSACELLGDDKLGREIHGYILRTEFAEDVSVCNSLIQMYSIIGHFTEAEKVFSRMEYKDVVSWTSMISCYGNNALPDKAVETYRMMEREGIMPDEITIACVLSACACLGNLDMGMKLHELAYRTGYISYVIVANTLIDMYSKCKCVDKALEVFHGIPSKNVISWSSIILGLRTNNRCFEALIFFRQMKLR-LKPNSVTLVSVLSACARIGALMCGKEIHAHALRTGVAFDGHLPNALLDLYVRCGRMGPAWNQFN-YNKKDVAAWNILLTGYAQRGQGKQAVELFHSMVESGLDPDEITFISLLCACSRSGMVSEGLEYFRSMKLEYFITPNLKHYACVVDLLGRDGQLDNAHEFIQKMPINPDPAIWGALLNACMINKKVELGELAAEQIFKMDTESVGYYVLMCNLYADSGKWEEVALVRKMMRKRGLTVDPGCSWVEVKGKVHAFLSGDNLHPQFKEINAVMDGFYEKMRSAGVKEPETRPTDEFEAS-KAEIFCGHSERLAVAFGLINTAPGMPIWVTKNLYMCQSCHSTIKFISKVVRREISVRDTEKFHHFKDGSCTCGDEGYW 869          

Query:  373 LKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWD 1842
            LK   ++ +L  A+     M+   V+     +  L+++C        G  +++++ +S    ++    A+++M+ +   + +A+ +F RM ERD+ SWN ++ GYA+ G    AL L  RM   G  PD  T   +L        L  G+ IH +V+R  FES V++  AL+ MY KCG++GTAR +F++M ++  +SWN+MI GY +N +  E +++F  M +    P  +T+   + AC  LGD + G+ +H  + + +   DVSV NSL+ MYS       A K+F  +  K +VSW +MI  Y  N    +A+  +  M+ + + PD  T+  V+ A A L        +H L  RT +   + V   L+DMY+KC  V  A ++F  +  ++V +W+++I G  TN     A+  F +M K  +KPN +T + V+SAC+  G +  G +  A +++     +  + +  A++DL  R G++  AW+
Sbjct:   66 LKKLCRHGNLEQALKLLDSMQEVQVKVDEDGYVALVRLCEWKRTHEEGARVYSYISNSTTLLSVRLGNALLSMFVRFGNLVDAWYVFGRMGERDVFSWNVLVGGYAKAGFFDEALNLYHRMLWVGIVPDIYTFPCVLRTCGGVPDLARGREIHLHVIRFGFESDVDVVNALITMYVKCGALGTARKLFDKMPRRDRISWNAMISGYFENGEFLEGLKLFLMMRESSIYPDLMTMTSLVSACELLGDDKLGREIHGYILRTEFAEDVSVCNSLIQMYSIIGHFTEAEKVFSRMEYKDVVSWTSMISCYGNNALPDKAVETYRMMEREGIMPDEITIACVLSACACLGNLDMGMKLHELAYRTGYISYVIVANTLIDMYSKCKCVDKALEVFHGIPSKNVISWSSIILGLRTNNRCFEALIFFRQM-KLRLKPNSVTLVSVLSACARIGALMCGKEIHAHALRTGVAFDGHLPN--ALLDLYVRCGRMGPAWN 553          

Query:  157 VYTHPAAILLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELS-VTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDGYGTN---GLGKAAVDLFNEMEKGTI 1659
            +YT P   +L  C  + +L    +I   +I+ G  ++      L++++   G+   A ++F+ +  +  + ++ ++ GY +N    + +  F  M+   + P +   T L+  C    D + G+EIH +++ + FA ++    +++ MY+      EA K+F RM  +D+VSW ++I+ Y  N L   A+E    M+ EG  PD IT+  +L A A  G+L +G  +H    R  + S V ++  L+DMYSKC  V  A  +F+ +  K  +SW+S+I G   N    EA+ IF + +    +P +VT++  L ACA +G L  GK +H    +  +  D  + N+L+ +Y +C R+  A   F N   K + +WN ++ GYAQ G+  +A+  F  M    + PD  T +S++ A +    V+   ++   + +      N+     +VD+  + G +  A +    M        W A+++    N    LG+ A +   +M+  ++
Sbjct:  195 IYTFPC--VLRTCGGVPDLARGREIHLHVIRFGFESDVDVVNALITMYVKCGALGTARKLFDKMPRRDRISWNAMISGYFENGEFLEGLKLFLMMRESSIYPDLMTMTSLVSACELLGDDKLGREIHGYILRTEFAEDVSVCNSLIQMYSIIGHFTEAEKVFSRMEYKDVVSWTSMISCYGNNALPDKAVETYRMMEREGIMPDEITIACVLSACACLGNLDMGMKLHELAYRTGYISYVIVANTLIDMYSKCKCVDKALEVFHGIPSKNVISWSSIILGLRTNNRCFEAL-IFFRQMKLRLKPNSVTLVSVLSACARIGALMCGKEIHAHALRTGVAFDGHLPNALLDLYVRCGRMGPAWNQF-NYNKKDVAAWNILLTGYAQRGQGKQAVELFHSMVESGLDPDEITFISLLCACSRSGMVSEGLEYFRSMKLEYFITPNLKHYACVVDLLGRDGQLDNAHEFIQKMPINPDPAIWGALLNACMINKKVELGELAAEQIFKMDTESV 699          

Query:  232 IIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDT-NSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            II NG  N+    TKL   F +  +   A  +F ++       ++ +++G+A N++   A+S +  + K+  ++P  + + + +       D + G  +HAH I  G   NL+  + VV+ Y K  ++  A K+FD +PE+D V WNT+I+G  +N     ++ +   M   G   DS T  T+LPAVA+   L  G  +H   L+A   S V++ T L+ +YSKC  + TARL+F  + +   + +N+MI GY  N + E ++ +F+ +L  G +  + TI+  +   +  G L     +     +  + S  SV  + +++Y +   ++ A ++F     KTL SWN MI GY QNG    A+S F +M S+   P+  T+ S++ A A+L      KW+HGL+     + NI+V+T+LVDMYAKCG++  ARKLFD M E++V TWNAMI  YG +G G  A+ LF EM    I P+ +TFL  + ACSH+GLV EG + F  M  ++G EP  +HY  MVD+LGRAG+L +A +FI+++P EPG  V+GA+LGAC  HKN EL   A++++FEL+P   GY+VLL+N+YS    + K A VR++++ + L KTPGC+LV++    H F  G  SHPQ+K IY  L+ L  ++  AG+  +T  ++HDVE + KE ++  HSEKLAIAF L+ T PGT I I KNLRVC DCHNATK+IS +T R I+VRD +RFHHFK+G CSCGDYW
Sbjct:  595 IILNGYQNDLATVTKLTHKFSDLKAMRHARDLFLSIARPDLFLFNVVIRGFAANAAPFSAISLYTHLRKNTNLKPDKFTYAFAVSAASGFKDEKYGVLLHAHSIVDGLGLNLYVGSIVVDFYFKFSRVELAQKVFDGLPEKDTVLWNTMISGLVRNCYYSDSMRVFGDMVVGGMGFDSTTXATVLPAVAELQELKAGMGVHCLALKAGXHSDVHVLTGLVSLYSKCKELETARLLFGHISRTDLICYNAMIAGYTCNNETESSVSLFRDLLASGEKVNSSTIVGLIPVSSPFGHLHLTGSLQTFCVKSGIVSHPSVSTAFVTVYCRLNEIESARQLFDQSKEKTLASWNAMISGYTQNGLTETAISLFREMXSE-FSPNPVTVTSILSACAQLGAISLGKWVHGLIKSKNLESNIYVLTSLVDMYAKCGSIVEARKLFDSMTEKNVVTWNAMISAYGLHGDGHEALKLFTEMLHSGISPSAVTFLSXLYACSHAGLVREGEEIFDHMVHNHGFEPLPEHYACMVDILGRAGKLEKALEFIKELPGEPGPPVWGALLGACMIHKNTELAXVASERLFELDPDNTGYYVLLSNVYSADRNFPKAASVRQVVKNRNLAKTPGCTLVEIGETPHVFICGDXSHPQAKAIYRMLDKLMGKMAEAGFQTETVTALHDVEEEEKELMMKVHSEKLAIAFALIETAPGTEIRIFKNLRVCLDCHNATKFISKITERVIVVRDANRFHHFKDGVCSCGDYW 1345          

Query:  229 LIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGK 1125
            L +K G +++    T LVSL+        A  +F  +     + Y+ ++ GY  N+    ++S F  + + G +        L+ V      L     +    + SG  ++    TA V +Y +  +I  A ++FD+  E+ L SWN +I+GY QNGL + A+ L   M  E   P+ +T+ ++L A A  G++ +GK +H  +   + ES + + T+L+DMY+KCGS+  AR +F+ M +K  V+WN+MI  Y  + D  EA+++F +ML  G  P+ VT +  L+AC+  G +  G+
Sbjct:  797 LALKAGXHSDVHVLTGLVSLYSKCKELETARLLFGHISRTDLICYNAMIAGYTCNNETESSVSLFRDLLASGEKVNSSTIVGLIPVSSPFGHLHLTGSLQTFCVKSGIVSHPSVSTAFVTVYCRLNEIESARQLFDQSKEKTLASWNAMISGYTQNGLTETAISLFREMXSE-FSPNPVTVTSILSACAQLGAISLGKWVHGLIKSKNLESNIYVLTSLVDMYAKCGSIVEARKLFDSMTEKNVVTWNAMISAYGLHGDGHEALKLFTEMLHSGISPSAVTFLSXLYACSHAGLVREGE 1094          

Query:  181 LLELCTSIKELN---QIIPLIIKNGL-YNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGD---NADLRRGKEIHAH-LISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVN-ISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLD-EGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQ-----------------SQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEM-----EKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPME-PGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +L+  T I++LN   QI   ++K G   +       LV+++   G   +A +VF+ + D+ +V +++++    +      A+  F  M  + + P  +    +   C +      LR GK++HA+ L  S + T  F + A++ MYAK   +  +  +F+   + D+VSWNT+I+ ++QN     ALE    M   G KPD +T+ ++LPA +    L  GK IHAY LR +  S  + + +AL+DMY  C  VG+ R +F+ + ++    WN+MI GY QNE  EEA+++F +M       P + T+   + AC         + +H  V +  L  +  V N+L+ MYS+  +  I+  IF ++  K +VSWNTMI GY  +GR  +AL+  C MQ                 S  +KP+S T ++++P  A L    + K IH   IR     ++ V +ALVDMYAKCG +  AR +F+ +  ++V TWN +I  YG  G G+ A++L  +M         ++PN++TF+ + +ACSHSG+V+EGL  F  MKEDYG+EPA DHY  +VDLLGRAG + EA+ FI  MP +      + ++LGACR H+NVE+GE AA+ + +L P    ++VLL+NIYS++  W+K   VR+ M   G++K PG S ++  +EVH F +G  SH QS++++ FLETL +++K  GYVPDT+ + H+V+ + KE LL  HSEKLAIAFG+LNT PGTTI + KNLRVC DCH A+KYIS +T REII+RD+ RFHHFKNGTCSCGDYW
Sbjct:  107 VLKAVTGIQDLNLGKQIHAHVVKFGYGLSSVTVANTLVNVYGKCGDIGDACKVFDGITDRDQVSWNSMIAALCRIEEWELALDAFRSMLLENMEPSSFTLVSVAHACSNLHKRDGLRLGKQVHAYGLRVSDWKT--FTINALLAMYAKLGLVEYSRALFEMFEDCDMVSWNTMISSFSQNDQFMEALEFFRLMVLAGLKPDGVTVASVLPACSHLEMLDTGKEIHAYALRTTELSENSYVGSALVDMYCNCRQVGSGRQVFDAVLERKIPLWNAMITGYAQNEYDEEALKLFLEMYAASALFPNSTTMSSIVPACVRSESFADKESIHGYVIKRGLEKNRYVQNALVDMYSRLGKTVISEIIFNSMEAKDIVSWNTMITGYVISGRHGDALNLLCDMQRVEEKKNTDYTGYDNEKSIPLKPNSITFMTILPGCAALGALAKGKEIHAYAIRNLLAFDVAVGSALVDMYAKCGCIGLARTVFNQIPIKNVITWNVLIMAYGMQGRGEEALELLRDMVDEGRRNKEVRPNEVTFIALFAACSHSGMVDEGLNLFRKMKEDYGIEPAPDHYACVVDLLGRAGNVEEAYQFINSMPSQLDKAGAWSSLLGACRIHQNVEIGEVAANHLLQLEPDVASHYVLLSNIYSSSGFWEKAMDVRRKMRELGVRKEPGYSWIEFGDEVHKFLAGDLSHQQSRQLHEFLETLSEKMKREGYVPDTSCVLHNVDEEEKETLLCGHSEKLAIAFGILNTRPGTTIRVSKNLRVCNDCHTASKYISKITDREIILRDVRRFHHFKNGTCSCGDYW 905          

Query:  373 LKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFA-TNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADY---GSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHK-LVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQN-MKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEME-----KGT------------IKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKI------FELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPG--CSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAG 2208
            L+   +++   +A+S +  M   GV P  + F  +LK      DL  GK+IHAH++  G+  +++     +VN+Y KC  I +A K+FD + +RD VSWN++IA   +    ++AL+    M  E  +P S TLV++  A ++      L +GK +HAY LR S      I+ ALL MY+K G V  +R +F   +    VSWN+MI  + QN+   EA+E F+ M+  G +P  VT+   L AC+ L  L+ GK +H   +   +L  +  V ++L+ MY  C++V    ++F  +L + +  WN MI GYAQN    EAL  F +M + + + P+S TM S++PA          + IHG VI+   +KN +V  ALVDMY++ G    +  +F+ M+ + + +WN MI GY  +G    A++L  +M+     K T            +KPN ITF+ ++  C+  G + +G +  A +++     + A+    A+VD+  + G +  A     ++P++  IT    ++      +  E  E   D +       E+ P E  +  L A    +  + + +   RKM E  G++  P     +VDL                 +  Y F+ ++  ++  AG
Sbjct:   73 LRSQTRSNHFREAISTYIEMTLSGVAPDNFAFPAVLKAVTGIQDLNLGKQIHAHVVKFGYGLSSVTVANTLVNVYGKCGDIGDACKVFDGITDRDQVSWNSMIAALCRIEEWELALDAFRSMLLENMEPSSFTLVSVAHACSNLHKRDGLRLGKQVHAYGLRVSDWKTFTIN-ALLAMYAKLGLVEYSRALFEMFEDCDMVSWNTMISSFSQNDQFMEALEFFRLMVLAGLKPDGVTVASVLPACSHLEMLDTGKEIHAYALRTTELSENSYVGSALVDMYCNCRQVGSGRQVFDAVLERKIPLWNAMITGYAQNEYDEEALKLFLEMYAASALFPNSTTMSSIVPACVRSESFADKESIHGYVIKRGLEKNRYVQNALVDMYSRLGKTVISEIIFNSMEAKDIVSWNTMITGYVISGRHGDALNLLCDMQRVEEKKNTDYTGYDNEKSIPLKPNSITFMTILPGCAALGALAKGKEIHAYAIRNLLAFDVAVG--SALVDMYAKCGCIGLARTVFNQIPIKNVITWNVLIMAYGMQGRGEEALELLRDMVDEGRRNKEVRPNEVTFIALFAACSHSGMVDEGLNLFRKMKEDYGIEPAPDHYACVVDLLGRAGNV----------EEAYQFINSMPSQLDKAG 703          

Query:  649 RDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFE-SLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADL---GDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTC-FDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEM-EKGTIKPNDITFLCVISAC--SHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQ 1824
            R   +W   +    ++   + A+   I M   G  PD+     +L AV     L +GK IHA+V++  +  S V ++  L+++Y KCG +G A  +F+ +  +  VSWNSMI    + E+ E A++ F+ ML E  +P++ T++   HAC++L     L  GK VH    ++      ++ N+L++MY+K   V+ +  +F+      +VSWNTMI  ++QN +  EAL  F  M    +KPD  T+ SV+PA + L +    K IH   +RT    +N +V +ALVDMY  C  V + R++FD + ER +  WNAMI GY  N   + A+ LF EM     + PN  T   ++ AC  S S   +E +  +   +   GLE       A+VD+  R G+
Sbjct:   64 RTPATWVETLRSQTRSNHFREAISTYIEMTLSGVAPDNFAFPAVLKAVTGIQDLNLGKQIHAHVVKFGYGLSSVTVANTLVNVYGKCGDIGDACKVFDGITDRDQVSWNSMIAALCRIEEWELALDAFRSMLLENMEPSSFTLVSVAHACSNLHKRDGLRLGKQVHAYGLRVSDWKTFTI-NALLAMYAKLGLVEYSRALFEMFEDCDMVSWNTMISSFSQNDQFMEALEFFRLMVLAGLKPDGVTVASVLPACSHLEMLDTGKEIHAYALRTTELSENSYVGSALVDMYCNCRQVGSGRQVFDAVLERKIPLWNAMITGYAQNEYDEEALKLFLEMYAASALFPNSTTMSSIVPACVRSESFADKESIHGYVIKR---GLEKNRYVQNALVDMYSRLGK 459          

Query:  277 LVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPER-DLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVS--VMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTN-SIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +++ + N G  +EA ++F+    K  + + +L+ GY +N S  +A   F RM+ +G +P  Y    +L++C     L+RG  +H ++  + F  N+F +T +V+MYAKC++I+EA  +F+ + +R + V W  ++ GY+QNG    A++    M+ EG + +  T  ++L A A   +   G  +H  V+++   + V + ++L+DMY KCG + +A+     M+    VSWNSMI G V+   AEEA+ +F+ M     +  + T    L++ A + D+     +H L+  +K G DV   V N+L+ MY+K   +D A ++FK +  K ++SW ++I GY +NG   +AL  FC+M++  + PD F + S + A AEL+V    + IH   I++    ++ V  + V MYAKCG +  A K+FD M  + V TW A+I GY  NG GK ++  +++M     +P+ ITF+ +I ACSH+GL+E+G  YF  M   YG++P  +HY  M+DLLGR+G+L+EA   + KM +EP  TV+ A+L ACR H N+ELGERAA  +F+L P+    +V L+N+YS AS W+  A++R++M+ KG+ K PGCS ++  ++VHTF S   SH ++  IY+ ++ +   IK AGYVPD N ++HD++ + KE  L  HSEKLA+AFGLL T PG  I I KNLRVCGDCH A K+IS V  R II+RD + FHHFK G CSC DYW
Sbjct:  148 MIAAYANSGRLAEAKQLFDATPSKNSITWSSLISGYCRNESESEAFELFWRMQFEGHKPSQYTLGSVLRLCSTLGLLQRGALVHGYMTKTQFDNNIFVVTGLVDMYAKCKRISEAEYLFETLFDRKNHVLWTVMLTGYSQNGDGFKAMKFFRDMRAEGVESNQFTFPSVLTASASVLAHSFGAQVHGCVVQSGLGANVFVQSSLVDMYVKCGDLNSAKKALRSMEVDNVVSWNSMIVGCVRQGFAEEALSLFKDMRSREMKIDHFTYPSVLNSFAVMKDMTNAMSIHCLI--IKTGFDVYQLVGNALVDMYAKQGNIDAAVEVFKCMSDKDVISWTSLITGYVRNGSHEKALRLFCEMRTAGIYPDQFVIASALSASAELTVLEFGQQIHANFIKSGLQASLSVDNSFVAMYAKCGCIEDANKVFDSMQVQDVITWTALIVGYAQNGRGKESLKFYDQMILTGAEPDFITFIGLIFACSHAGLLEKGRYYFELMSRVYGIQPGSEHYACMIDLLGRSGKLNEAEALVNKMVVEPDGTVWKALLAACRVHGNIELGERAAMNLFKLEPLNAVPYVQLSNMYSAASRWEDAARIRRLMKSKGILKEPGCSWIETNSQVHTFMSEDRSHSRTAEIYSKVDEIMMLIKEAGYVPDMNFALHDMDKEGKELGLAYHSEKLAVAFGLLTTPPGAPIRIFKNLRVCGDCHTAMKFISKVYLRHIILRDSNCFHHFKEGNCSCDDYW 884          

Query:  565 FAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRM-KQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVE 1926
            F+   ++  YA   ++ EA ++FD  P ++ ++W+++I+GY +N     A EL  RMQ EG KP   TL ++L   +  G L  G  +H Y+ +  F++ + + T L+DMY+KC  +  A  +F  +  +K  V W  M+ GY QN D  +AM+ F+ M  EG +    T    L A A +     G  VH  V Q  LG++V V +SL+ MY KC  ++ A K  +++    +VSWN+MI+G  + G   EALS F  M+S+ MK D FT  SV+ + A +     A  IH L+I+T FD    V  ALVDMYAK G +  A ++F  M ++ V +W ++I GY  NG  + A+ LF EM    I P+       +SA +   ++E G Q  A+  +  GL+ ++    + V +  + G + +A      M ++  IT    ++G  +  +  E
Sbjct:  143 FSWNTMIAAYANSGRLAEAKQLFDATPSKNSITWSSLISGYCRNESESEAFELFWRMQFEGHKPSQYTLGSVLRLCSTLGLLQRGALVHGYMTKTQFDNNIFVVTGLVDMYAKCKRISEAEYLFETLFDRKNHVLWTVMLTGYSQNGDGFKAMKFFRDMRAEGVESNQFTFPSVLTASASVLAHSFGAQVHGCVVQSGLGANVFVQSSLVDMYVKCGDLNSAKKALRSMEVDNVVSWNSMIVGCVRQGFAEEALSLFKDMRSREMKIDHFTYPSVLNSFAVMKDMTNAMSIHCLIIKTGFDVYQLVGNALVDMYAKQGNIDAAVEVFKCMSDKDVISWTSLITGYVRNGSHEKALRLFCEMRTAGIYPDQFVIASALSASAELTVLEFGQQIHANFIKS-GLQASLSVDNSFVAMYAKCGCIEDANKVFDSMQVQDVITWTALIVGYAQNGRGKE 596          

Query:  145 IPSHVYTHPAAILLELCTSIKELN-QIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQL 1152
            + S+ +T P+ +             Q+   ++++GL      Q+ LV ++   G  + A +   ++E    V +++++ G  +     +A+S F  M+S  ++   + +  +L       D+     IH  +I +GF        A+V+MYAK   I+ A ++F  M ++D++SW ++I GY +NG  + AL L   M+  G  PD   + + L A A+   L  G+ IHA  +++  ++ +++  + + MY+KCG +  A  +F+ M+ +  ++W ++I GY QN   +E+++ + +M+  G +P  +T +  + AC+  G LE+G++  +L+ ++
Sbjct:  306 VESNQFTFPSVLTASASVLAHSFGAQVHGCVVQSGLGANVFVQSSLVDMYVKCGDLNSAKKALRSMEVDNVVSWNSMIVGCVRQGFAEEALSLFKDMRSREMKIDHFTYPSVLNSFAVMKDMTNAMSIHCLIIKTGFDVYQLVGNALVDMYAKQGNIDAAVEVFKCMSDKDVISWTSLITGYVRNGSHEKALRLFCEMRTAGIYPDQFVIASALSASAELTVLEFGQQIHANFIKSGLQASLSVDNSFVAMYAKCGCIEDANKVFDSMQVQDVITWTALIVGYAQNGRGKESLKFYDQMILTGAEPDFITFIGLIFACSHAGLLEKGRYYFELMSRV 642          

Query:  100 APQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +P      T S RT+IPSHVY HP+AILLELCTS+KEL+Q IPLIIKNGLY+EHLFQTKLVSLFC +GS  EA RVF+ +EDK++  YHT+LKGYA+NSSL DA+SFFCRM+ DGVRPVVYNFTYLLKVCGDNADLR+GKEIH  LI +GFA+N+FAMT VVNMYAKCR + EAYKMFDRMPERDLV WNTII+GYAQNG  K ALELV+RMQEEG++PDSIT+V++LPAVAD GSL IG+SIH Y +RA FES VN+STAL+DMYSKCGSVGTARLIF+RM  KT VSWNSMIDGYVQN D   AMEIFQKM+DE  + TNVT+M ALHACADLGD+E+G+FVHKL+DQL+LGSDVSVMNSL+SMYSKCKRVDIAA+IF+NL  KTLVSWN MILGYAQNGR++EA+ +FC+MQ QN+KPDSFTMVSVIPALAELSV  QAKWIHGLVIRTC DKN+FV TALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGT+GLGKAA++LF +M+K  IKPN++TFLCV+SACSHSGLVEEG QYF SMK+DYGLEPAMDHYGAMVDLLGRA +L+EAWDFIQKMP+EP I+VFGAMLGACR HKNVELGE+AA++IF+L+P +GGYHVLLANIY+TAS+WDKVA+VR  ME KG+QKTPG S+V+L+NEVHTFYSG+TSHPQ+K+IY FLETLG+ IKAAGY+PDTNS+HDVE  VKEQLLNSHSEKLAIAF LLNT+PGTTIH+RKNLRVCGDCHNATKYISLVT REIIVRDM RFHHFK+GTCSCGDYW
Sbjct:   56 SPTSNLHRTPSSRTYIPSHVYKHPSAILLELCTSMKELHQFIPLIIKNGLYSEHLFQTKLVSLFCKFGSLHEAARVFQPIEDKIDELYHTMLKGYARNSSLDDAVSFFCRMRYDGVRPVVYNFTYLLKVCGDNADLRKGKEIHCQLIVNGFASNVFAMTGVVNMYAKCRLVEEAYKMFDRMPERDLVCWNTIISGYAQNGFGKTALELVLRMQEEGKRPDSITIVSILPAVADVGSLRIGRSIHGYSMRAGFESFVNVSTALVDMYSKCGSVGTARLIFDRMTGKTVVSWNSMIDGYVQNGDPGAAMEIFQKMMDEQVEMTNVTVMGALHACADLGDVEQGRFVHKLLDQLELGSDVSVMNSLISMYSKCKRVDIAAEIFENLQHKTLVSWNAMILGYAQNGRINEAIDYFCKMQLQNIKPDSFTMVSVIPALAELSVLPQAKWIHGLVIRTCLDKNVFVATALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTHGLGKAALELFEKMKKEVIKPNEVTFLCVLSACSHSGLVEEGFQYFGSMKKDYGLEPAMDHYGAMVDLLGRANRLNEAWDFIQKMPIEPAISVFGAMLGACRIHKNVELGEKAANRIFDLDPDDGGYHVLLANIYATASMWDKVARVRTTMEKKGIQKTPGWSVVELQNEVHTFYSGTTSHPQAKKIYAFLETLGNRIKAAGYMPDTNSVHDVEDVVKEQLLNSHSEKLAIAFSLLNTSPGTTIHLRKNLRVCGDCHNATKYISLVTKREIIVRDMRRFHHFKDGTCSCGDYW 849          

Query:  127 LSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            L QR  IPSHVY HP+AILLELCTS+KEL+QI+PLIIKNG YNEHLFQTKL+SLFC + S +EA RVFE VE KL+V YHT+LKGYAKNS+L DA+ F+ RM+ D V PVVY+FTYLL++ G+N DLRRG+EIH  +I++GF +NLFAMTAVVN+YAKCRQI +AYKMF+RMP+RDLVSWNT++AGYAQNG A+ A+++V++MQE GQKPDSITLV++LPAVAD  +L IG+SIH Y  RA FE +VN++TA+LD Y KCGSV +ARL+F  M  +  VSWN+MIDGY QN ++EEA   F KMLDEG +PTNV++M ALHACA+LGDLERG++VH+L+D+ K+G DVSVMNSL+SMYSKCKRVDIAA +F NL  KT+V+WN MILGYAQNG V+EAL+ FC+MQS ++KPDSFT+VSVI ALA+LSVTRQAKWIHGL IRT  DKN+FV TAL+D +AKCGA+ TARKLFD+M ERHV TWNAMIDGYGTNG G+ A+DLFNEM+ G++KPN+ITFL VI+ACSHSGLVEEG+ YF SMKE+YGLEP MDHYGAMVDLLGRAG+L +AW FIQ MP++PGITV GAMLGACR HKNVELGE+ AD++F+L+P +GGYHVLLAN+Y++AS+WDKVA+VR  ME KG+QKTPGCSLV+LRNEVHTFYSGST+HPQSKRIY +LETLGDE+KAAGYVPDTNSIHDVE DVKEQLL+SHSE+LAIAFGLLNT  GT IHIRKNLRVCGDCH ATKYISLVTGREIIVRD+ RFHHFKNG CSCGDYW
Sbjct:   32 LYQRIFIPSHVYRHPSAILLELCTSLKELHQILPLIIKNGFYNEHLFQTKLISLFCKFNSITEAARVFEPVEHKLDVLYHTMLKGYAKNSTLRDAVRFYERMRCDEVMPVVYDFTYLLQLSGENLDLRRGREIHGMVITNGFQSNLFAMTAVVNLYAKCRQIEDAYKMFERMPQRDLVSWNTVVAGYAQNGFARRAVQVVLQMQEAGQKPDSITLVSVLPAVADLKALRIGRSIHGYAFRAGFEYMVNVATAMLDTYFKCGSVRSARLVFKGMSSRNVVSWNTMIDGYAQNGESEEAFATFLKMLDEGVEPTNVSMMGALHACANLGDLERGRYVHRLLDEKKIGFDVSVMNSLISMYSKCKRVDIAASVFGNLKHKTVVTWNAMILGYAQNGCVNEALNLFCEMQSHDIKPDSFTLVSVITALADLSVTRQAKWIHGLAIRTLMDKNVFVCTALIDTHAKCGAIQTARKLFDLMQERHVITWNAMIDGYGTNGHGREALDLFNEMQNGSVKPNEITFLSVIAACSHSGLVEEGMYYFESMKENYGLEPTMDHYGAMVDLLGRAGRLDDAWKFIQDMPVKPGITVLGAMLGACRIHKNVELGEKTADELFDLDPDDGGYHVLLANMYASASMWDKVARVRTAMEKKGIQKTPGCSLVELRNEVHTFYSGSTNHPQSKRIYAYLETLGDEMKAAGYVPDTNSIHDVEEDVKEQLLSSHSERLAIAFGLLNTRHGTAIHIRKNLRVCGDCHEATKYISLVTGREIIVRDLRRFHHFKNGICSCGDYW 816          

Query:  370 LLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +LKGYAK+SSL  A+SFF RMK D VRPVVYNFTYLLK+CGDN+DL+RGKEIH  +I+SGF+ NLFAMT VVNMYAKCRQIN+AY MFDRMPERDLV WNT+I+GYAQNG AK+AL LV+RM EEG +PDSIT+V++LPAVAD   L IG ++H YVLRA FESLVN+STAL+DMYSKCGSV  AR+IF+ M  +T VSWNSMIDGYVQ+ DAE AM IFQKMLDEG QPTNVT+M ALHACADLGDLERGKFVHKLVDQLKL SDVSVMNSL+SMYSKCKRVDIAA IFKNL  KTLVSWN MILGYAQNG V+EAL+ FC+MQS+N+KPDSFTMVSVIPALAELS+ RQAKWIHGLVIR   DKN+FVMTALVDMYAKCGA+HTARKLFDMM+ RHV TWNAMIDGYGT+GLGK +V+LF EM+KGTIKPNDITFLC +SACSHSGLVEEGL +F SMK+DYG+EP MDHYGAMVDLLGRAG+L++AWDFIQKMP++PGITV+GAMLGAC+ HKNV+LGE+AA +IF+LNP +GGYHVLLANIY+TAS+W KVAKVR +ME  GLQKTPGCSLV++ NEVH+FYSG+TSHPQSK+IY++LETL DEI+AAGYVPDTNSIHDVE DVK QLLN+HSEKLAIAFGLLNT+ GT IHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFH FK+G CSCGDYW
Sbjct:    1 MLKGYAKSSSLDSALSFFSRMKHDSVRPVVYNFTYLLKLCGDNSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPERDLVCWNTMISGYAQNGFAKVALMLVLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKMLDEGVQPTNVTVMGALHACADLGDLERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEEGLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQKMPIKPGITVYGAMLGACKIHKNVDLGEKAAFEIFKLNPDDGGYHVLLANIYATASMWGKVAKVRTIMEKSGLQKTPGCSLVEIGNEVHSFYSGTTSHPQSKKIYSYLETLVDEIRAAGYVPDTNSIHDVEDDVKVQLLNTHSEKLAIAFGLLNTSTGTPIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHLFKDGVCSCGDYW 704          

Query:  181 LLELC---TSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFV------MTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMIDG---YGTNGLG-KAAVDLF 1635
            LL+LC   + +K   +I   +I +G        T +V+++      ++A+ +F+ + ++  V ++T++ GYA+N     A+    RM  +G RP       +L    D   LR G  +H +++ +GF + +   TA+V+MY+KC  ++ A  +FD M  R +VSWN++I GY Q+G A+ A+ +  +M +EG +P ++T++  L A AD G L  GK +H  V +   +S V++  +L+ MYSKC  V  A  IF  ++ KT VSWN+MI GY QN    EA+  F +M     +P + T++  + A A+L    + K++H LV +  L  +V VM +L+ MY+KC  +  A K+F  +  + +++WN MI GY  +G    ++  F +M+   +KP+  T +  + A +   +  +     GL       K+  +        A+VD+  + G ++ A      M  +  +T + AM+     +    LG KAA ++F
Sbjct:   36 LLKLCGDNSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPERDLVCWNTMISGYAQNGFAKVALMLVLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKMLDEGVQPTNVTVMGALHACADLGDLERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEE-----GLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQKMPIKPGITVYGAMLGACKIHKNVDLGEKAAFEIF 529          

Query:  133 QRTHIPSHVYTH--PAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            Q   IP+ VY+H  P+ +LLE CTS KEL QI+P IIKNG YNEHLFQTK++SLFC +GS SEA RVFE VE KL+V YH +LKGYAKNSSLGDA+ FF RM  D VR VV ++  LL++CG+N DL++G+EIH  +I++GF +NLF MTAV+++YAKCRQI+ AYKMF+RM  +DLVSW T++AGYAQNG AK AL+LV++MQE GQKPDS+TLV++LPAVAD  +L IG+SIH Y  R+ FESLVN++ ALLDMY KCGS   ARL+F  M+ KT VSWN+MIDG  QN ++EEA   F KMLDEG  PT VT+M  L ACA+LGDLERG FVHKL+D+LKL S+VSVMNSL+SMYSKCKRVDIAA IF NL  KT V+WN MILGYAQNG V EAL+ FC MQSQ +K D FT+V VI ALA+ SV RQAKWIHGL +R C D N+FV TALVDMYAKCGA+ TARKLFDMM ERHV TWNAMIDGYGT+G+GK  +DLFNEM+KG +KPNDITFL VISACSHSG VEEGL  F SM+EDY LEP MDHY AMVDLLGRAGQL +AW+FIQ+MP++PGI+V GAMLGAC+ HKNVELGE+AA K+F+L+P EGGYHVLLANIY++ S+WDKVAKVR  ME KGL KTPGCS V+LRNE+HTFYSGST+HP+SK+IY FLETLGDEIKAAGYVPD +SIHDVE DVK+QLL+SHSE+LAIAFGLLNT+PGTT+HIRKNLRVCGDCH+ TKYISLVTGREIIVRD+ RFHHFKNG+CSCGDYW
Sbjct:   35 QSNSIPTRVYSHRHPSVVLLENCTSKKELYQILPFIIKNGFYNEHLFQTKVISLFCKFGSNSEAARVFEHVELKLDVLYHIMLKGYAKNSSLGDALCFFLRMMCDEVRLVVGDYACLLQLCGENLDLKKGREIHGLIITNGFESNLFVMTAVMSLYAKCRQIDNAYKMFERMQHKDLVSWTTLVAGYAQNGHAKRALQLVLQMQEAGQKPDSVTLVSILPAVADMKALRIGRSIHGYAFRSGFESLVNVTNALLDMYFKCGSARIARLVFKGMRSKTVVSWNTMIDGCAQNGESEEAFATFLKMLDEGEVPTRVTMMGVLLACANLGDLERGWFVHKLLDKLKLDSNVSVMNSLISMYSKCKRVDIAASIFNNL-EKTNVTWNAMILGYAQNGCVKEALNLFCMMQSQGIKLDCFTLVGVITALADFSVNRQAKWIHGLAVRACMDNNVFVSTALVDMYAKCGAIKTARKLFDMMQERHVITWNAMIDGYGTHGVGKETLDLFNEMQKGAVKPNDITFLSVISACSHSGFVEEGLLLFKSMQEDYYLEPTMDHYSAMVDLLGRAGQLDDAWNFIQEMPIKPGISVLGAMLGACKIHKNVELGEKAAQKLFKLDPDEGGYHVLLANIYASNSMWDKVAKVRTAMEDKGLHKTPGCSWVELRNEIHTFYSGSTNHPESKKIYAFLETLGDEIKAAGYVPDPDSIHDVEEDVKKQLLSSHSERLAIAFGLLNTSPGTTLHIRKNLRVCGDCHDTTKYISLVTGREIIVRDLRRFHHFKNGSCSCGDYW 818          

Query:  121 HTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            H LSQR +IP++VY HPAA+LLE C+S+KEL  I+PLI KNGLY EHLFQTKLVSLFC YGS  EA RVFE ++ KL V Y+T+LKG+AK S L  A+ FF RM+ D V PVVYNFTYLLKVCGD A+LR GKEIH  L+ SGF+ +LFAMT + NMYAKCRQ++EA K+FDRMPERDLVSWNTI+AGY+QNG+A++ALE+V  M EE  KP  IT+V++LPAV+    + IGK IH Y +RA F+SLVNI+TAL+DMY+KCGS+ TARL+F+ M ++  VSWNSMID YVQNE+ +EAM IFQKMLDEG +PT+V++M ALHACADLGDLERG+F+HKL  +L+L  +VSV+NSL+SMY KCK VD AA +F  L  +T+VSWN MILG+AQNGR  EAL++F QMQ++ +KPD+FT VSVI A+AELS+T  AKWIHG+V+R C DKN+FV TALVDMYAKCGA+  AR +FDMM ERHVTTWNAMIDGYGT+G+GKAA++LF EM+KGTI+PN +TFL VISACSHSGLVE GL+ F  MKE+Y +EP+MDHYGAMVDLLGRAG+L+EAWDFI +MP++P + V+GAMLGAC+ HKNV   E+ A+++FELNP +GGYHVLLANIY  AS+W+KV +VR  M  +GL+KTPGCS+V+++NEVH+F+SGST+HP SK+IY FLE L  +IK AGYVPDTN I  +E DVKEQLL+SHSEKLAI+FGLLNTT GTTIH+RKNLRVC DCHNATKYISLVTGREIIVRDM RFHHFKNG CSCGDYW
Sbjct:   23 HFLSQRNYIPANVYEHPAALLLERCSSLKELRHILPLIFKNGLYQEHLFQTKLVSLFCRYGSVDEAARVFEPIDKKLNVLYYTMLKGFAKVSDLDKALKFFVRMRDDEVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVHEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVNLMCEENLKPSFITIVSVLPAVSALRLIRIGKEIHGYAMRAGFDSLVNIATALVDMYAKCGSLKTARLLFDGMLERNVVSWNSMIDAYVQNENPKEAMVIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELELDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTIVSWNAMILGFAQNGRPIEALNYFSQMQARTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRNCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGIGKAALELFEEMQKGTIRPNGVTFLSVISACSHSGLVEAGLKCFHMMKENYSIEPSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKVAERLFELNPEDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPSSKKIYAFLEKLICQIKEAGYVPDTNLILGLEDDVKEQLLSSHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIIVRDMQRFHHFKNGACSCGDYW 809          

Query:    1 MSSQLLHYTALLPITNSIXXXXXXXXXXXXXISAPQFQAFHTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            MSSQL+ ++ +  I N                  P  +  H LS+R +IP++VY HPAA+LLE C+S+KEL QI+PL+ KNGLY EH FQTKLVSLFC YGS  EA RVFE ++ KL V YHT+LKG+AK S L  A+ FF RM+ D V PVVYNFTYLLKVCGD A+LR GKEIH  L+ SGF+ +LFAMT + NMYAKCRQ+NEA K+FDRMPERDLVSWNTI+AGY+QNG+A++ALE+V  M EE  KP  IT+V++LPAV+    + +GK IH Y +R+ F+SLVNISTAL+DMY+KCGS+ TAR +F+ M ++  VSWNSMID YVQNE+ +EAM IFQKMLDEG +PT+V++M ALHACADLGDLERG+F+HKL  +L L  +VSV+NSL+SMY KCK VD AA +F  L  +TLVSWN MILG+AQNGR  +AL++F QM+S+ +KPD+FT VSVI A+AELS+T  AKWIHG+V+R+C DKN+FV TALVDMYAKCGA+  AR +FDMM ERHVTTWNAMIDGYGT+G GKAA++LF EM+KGTIKPN +TFL VISACSHSGLVE GL+ F  MKE+Y +E +MDHYGAMVDLLGRAG+L+EAWDFI +MP++P + V+GAMLGAC+ HKNV   E+AA+++FELNP +GGYHVLLANIY  AS+W+KV +VR  M  +GL+KTPGCS+V+++NEVH+F+SGST+HP SK+IY FLE L   IK AGYVPDTN +  VE DVKEQLL++HSEKLAI+FGLLNTT GTTIH+RKNLRVC DCHNATKYISLVTGREI+VRDM RFHHFKNG CSCGDYW
Sbjct:    1 MSSQLVQFSTVPQIPN------------------PPSRHRHFLSERNYIPANVYEHPAALLLERCSSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSKKIYAFLEKLICHIKEAGYVPDTNLVLGVENDVKEQLLSTHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIVVRDMQRFHHFKNGACSCGDYW 809          

Query:  361 YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +H  L+  A  S L  A++ F  M S G  PV+  FT LLK+C    DL  G+ +HA L + G  +   A TA+ NMYAKCR+  +A ++FDRMP RD V+WN ++AGYA+NGLA++A+E+V+RMQEE G++PDSITLV++LPA A+  +L   +  HA+ +R+  E LVN++TA+LD Y KCG +  AR++F+ M  K +VSWN+MIDGY QN D+ EA+ +F +M++EG   T+V+++ AL AC +LG L+ G  VH+L+ ++ L S+VSVMN+L++MYSKCKRVD+A+ +F  L  +T VSWN MILG AQNG   +A+  F +MQ +N+KPDSFT+VSVIPALA++S   QA+WIHG  IR   D++++V+TAL+DMYAKCG V+ AR LF+   ERHV TWNAMI GYG++G GKAAV+LF EM+   I PN+ TFL V+SACSH+GLV+EG +YF SMKEDYGLEP M+HYG MVDLLGRAG+L EAW FIQKMPM+PG++V+GAMLGAC+ HKNVEL E +A KIFEL P EG YHVLLANIY+ AS+W  VA+VR  ME  GLQKTPG S++ L+NE+HTFYSGST+H Q+K IY+ L  L +EIKA GYVPDT+SIHDVE DVK QLLN+HSEKLAIAFGL+ T PGTTI I+KNLRVC DCHNATK ISLVTGREII+RD+ RFHHFK+G CSCGDYW
Sbjct:   27 HHARLRASAARSDLPAALAAFVAMSSAGAPPVLRTFTSLLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQEGVYHVLLANIYANASMWKDVARVRTAMEKNGLQKTPGWSIIQLKNEIHTFYSGSTNHQQAKEIYSRLAKLIEEIKAVGYVPDTDSIHDVEDDVKAQLLNTHSEKLAIAFGLIRTAPGTTIQIKKNLRVCNDCHNATKLISLVTGREIIMRDIQRFHHFKDGKCSCGDYW 734          

Query:  181 LLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAK 1428
            LL+LC +  +L     +   +   G+ +E L  T L +++     P++A RVF+ +  +  V ++ L+ GYA+N     AM    RM + +G RP       +L  C +   L   +E HA  I SG    +   TA+++ Y KC  I  A  +FD MP ++ VSWN +I GYAQNG ++ AL L  RM EEG     ++++  L A  + G L  G  +H  ++R   +S V++  AL+ MYSKC  V  A  +F+ + ++T VSWN+MI G  QN  +E+A+ +F +M  E  +P + T++  + A AD+ D  + +++H    +L L  DV V+ +L+ MY+KC RV+IA  +F +   + +++WN MI GY  +G    A+  F +M+S  + P+  T +SV+ A +   +  + +
Sbjct:   65 LLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGR 484          

Query:  229 LIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLR-ASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVS-WNSMIDGYVQNEDAEEAMEIFQKMLDEGFQ 1056
            L+++ GL +       L++++        A  VF+ ++ + +V ++ ++ G A+N    DA+  F RM+ + V+P  +    ++    D +D  + + IH + I      +++ +TA+++MYAKC ++N A  +F+   ER +++WN +I GY  +G  K A+EL   M+  G  P+  T +++L A +  G +  G+     +      E  +     ++D+  + G +  A     +M     +S + +M+     +++ E A E  QK+ + G Q
Sbjct:  287 LLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQ 564          

Query:  361 YHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +H  L+  A  S L  A++ F  M S G  PV+  FT LLK+C    DL  G+ +HA L + G  +   A TA+ NMYAKCR+  +A ++FDRMP RD V+WN ++AGYA+NGLA++A+E+V+RMQEE G++PDSITLV++LPA A+  +L   +  HA+ +R+  E LVN++TA+LD Y KCG +  AR++F+ M  K +VSWN+MIDGY QN D+ EA+ +F +M++EG   T+V+++ AL AC +LG L+ G  VH+L+ ++ L S+VSVMN+L++MYSKCKRVD+A+ +F  L  +T VSWN MILG AQNG   +A+  F +MQ +N+KPDSFT+VSVIPALA++S   QA+WIHG  IR   D++++V+TAL+DMYAKCG V+ AR LF+   ERHV TWNAMI GYG++G GKAAV+LF EM+   I PN+ TFL V+SACSH+GLV+EG +YF SMKEDYGLEP M+HYG MVDLLGRAG+L EAW FIQKMPM+PG++V+GAMLGAC+ HKNVEL E +A KIFEL P EG YHVLLANIY+ AS+W  VA+VR  ME  GLQKTPG S++ L+NE+HTFYSGST+H Q+K IY+ L  L +EIKA GYVPDT+SIHDVE DVK QLLN+HSEKLAIAFGL+ T PGTTI I+KNLRVC DCHNATK ISLVTGREII+RD+ RFHHFK+G CSCGDYW
Sbjct:   27 HHARLRAAAARSDLPAALAAFVAMSSAGAPPVLRTFTSLLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQEGVYHVLLANIYANASMWKDVARVRTAMEKNGLQKTPGWSIIQLKNEIHTFYSGSTNHQQAKEIYSRLAKLIEEIKAVGYVPDTDSIHDVEDDVKAQLLNTHSEKLAIAFGLIRTAPGTTIQIKKNLRVCNDCHNATKLISLVTGREIIMRDIQRFHHFKDGKCSCGDYW 734          

Query:  181 LLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAK 1428
            LL+LC +  +L     +   +   G+ +E L  T L +++     P++A RVF+ +  +  V ++ L+ GYA+N     AM    RM + +G RP       +L  C +   L   +E HA  I SG    +   TA+++ Y KC  I  A  +FD MP ++ VSWN +I GYAQNG ++ AL L  RM EEG     ++++  L A  + G L  G  +H  ++R   +S V++  AL+ MYSKC  V  A  +F+ + ++T VSWN+MI G  QN  +E+A+ +F +M  E  +P + T++  + A AD+ D  + +++H    +L L  DV V+ +L+ MY+KC RV+IA  +F +   + +++WN MI GY  +G    A+  F +M+S  + P+  T +SV+ A +   +  + +
Sbjct:   65 LLKLCAARGDLATGRAVHAQLAARGIDSEALAATALANMYAKCRRPADARRVFDRMPVRDRVAWNALVAGYARNGLARMAMEMVVRMQEEEGERPDSITLVSVLPACANARALAACREAHAFAIRSGLEELVNVATAILDAYCKCGDIRAARVVFDWMPTKNSVSWNAMIDGYAQNGDSREALALFNRMVEEGVDVTDVSVLAALQACGELGCLDEGMRVHELLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGR 484          

Query:  229 LIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLR-ASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVS-WNSMIDGYVQNEDAEEAMEIFQKMLDEGFQ 1056
            L+++ GL +       L++++        A  VF+ ++ + +V ++ ++ G A+N    DA+  F RM+ + V+P  +    ++    D +D  + + IH + I      +++ +TA+++MYAKC ++N A  +F+   ER +++WN +I GY  +G  K A+EL   M+  G  P+  T +++L A +  G +  G+     +      E  +     ++D+  + G +  A     +M     +S + +M+     +++ E A E  QK+ + G Q
Sbjct:  287 LLVRIGLDSNVSVMNALITMYSKCKRVDLASHVFDELDRRTQVSWNAMILGCAQNGCSEDAVRLFTRMQLENVKPDSFTLVSVIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVNIARILFNSARERHVITWNAMIHGYGSHGFGKAAVELFEEMKSIGIVPNETTFLSVLSACSHAGLVDEGREYFTSMKEDYGLEPGMEHYGTMVDLLGRAGKLDEAWAFIQKMPMDPGLSVYGAMLGACKLHKNVELAEESAQKIFELGPQ 564          

Query:  361 YHTLLKGYAKNSSLGDAMSFFCRMK-SDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEE-GQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKMPMEPGITVFGAMLGACRTHKNVELGERAADKIFELNPVEGGYHVLLANIYSTASLWDKVAKVRKMMEMKGLQKTPGCSLVDLRNEVHTFYSGSTSHPQSKRIYTFLETLGDEIKAAGYVPDTNSIHDVEADVKEQLLNSHSEKLAIAFGLLNTTPGTTIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHHFKNGTCSCGDYW 2481
            +H  L+  A  S L  A++ F  M  + G  PV+  FT LLK+C   ADL  G+ +HA L + G +    A TA+ NMYAKCR+  +A ++FDRMP RD V+WN ++AGYA+NGLA+ A+ +V+RMQEE G++PD++TLV++LPA AD  +L   + +HA+ +R  F+  VN+STA+LD+Y KCG+V +AR +F+ M+ + +VSWN+MI GY +N DA EA+ +F++M+ EG   T+V+++ ALHAC +LG L+ G+ VH+L+ ++ L S+V+VMN+L++MY KCKR D+AA++F  L  KT VSWN MILG  QNG   +A+  F +MQ +N+KPDSFT+VS+IPALA++S   QA+WIHG  IR   D++++V+TAL+DMYAKCG V  AR LF+   +RHV TWNAMI GYG++G GK AV+LF EM+     PN+ TFL V+SACSH+GLV+EG +YF+SMKEDYGLEP M+HYG MVDLLGRAG+L EAW FIQKMPMEPGI+V+GAMLGAC+ HKNVEL E +A +IFEL P EG YHVLLANIY+ ASLW  VA+VR  ME KGLQKTPG S+V L+NE+HTFYSGST+H Q+K IY  L  L +EIKA GYVPDT+SIHDVE DVK QLLN+HSEKLAIA+GL+ T PGTTI I+KNLRVC DCHNATK ISLVTGREII+RD+ RFHHFK+G CSCGDYW
Sbjct:  192 HHARLRAAASRSDLRGALAAFAAMSPASGSGPVLRTFTSLLKLCAARADLATGRAVHAQLAARGLSPEALAATALANMYAKCRRPGDARRVFDRMPARDRVAWNALVAGYARNGLAEAAVGMVVRMQEEDGERPDAVTLVSVLPACADAQALGACREVHAFAVRGGFDEQVNVSTAILDVYCKCGAVDSARKVFDGMQDRNSVSWNAMIKGYAENGDATEALALFKRMVGEGVDVTDVSVLAALHACGELGFLDEGRRVHELLVRIGLESNVNVMNALITMYCKCKRTDLAAQVFDELGYKTRVSWNAMILGCTQNGSSEDAVRLFSRMQLENVKPDSFTLVSIIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVSIARSLFNSARDRHVITWNAMIHGYGSHGSGKVAVELFEEMKSSGKVPNETTFLSVLSACSHAGLVDEGQEYFSSMKEDYGLEPGMEHYGTMVDLLGRAGKLHEAWSFIQKMPMEPGISVYGAMLGACKLHKNVELAEESAQRIFELEPEEGVYHVLLANIYANASLWKDVARVRTAMEKKGLQKTPGWSIVQLKNEIHTFYSGSTNHQQAKDIYARLAKLIEEIKAVGYVPDTDSIHDVEDDVKAQLLNTHSEKLAIAYGLIRTAPGTTIQIKKNLRVCKDCHNATKLISLVTGREIIMRDIQRFHHFKDGKCSCGDYW 900          

Query:  181 LLELCTSIKEL---NQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRM-KSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQA-KWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMD-ERHVTTWNAMI 1587
            LL+LC +  +L     +   +   GL  E L  T L +++     P +A RVF+ +  +  V ++ L+ GYA+N     A+    RM + DG RP       +L  C D   L   +E+HA  +  GF   +   TA++++Y KC  ++ A K+FD M +R+ VSWN +I GYA+NG A  AL L  RM  EG     ++++  L A  + G L  G+ +H  ++R   ES VN+  AL+ MY KC     A  +F+ +  KT VSWN+MI G  QN  +E+A+ +F +M  E  +P + T++  + A AD+ D  + +++H    +L L  DV V+ +L+ MY+KC RV IA  +F +   + +++WN MI GY  +G    A+  F +M+S    P+  T +SV+ A +   +  +  ++   +      +  +     +VD+  + G +H A      M  E  ++ + AM+
Sbjct:  231 LLKLCAARADLATGRAVHAQLAARGLSPEALAATALANMYAKCRRPGDARRVFDRMPARDRVAWNALVAGYARNGLAEAAVGMVVRMQEEDGERPDAVTLVSVLPACADAQALGACREVHAFAVRGGFDEQVNVSTAILDVYCKCGAVDSARKVFDGMQDRNSVSWNAMIKGYAENGDATEALALFKRMVGEGVDVTDVSVLAALHACGELGFLDEGRRVHELLVRIGLESNVNVMNALITMYCKCKRTDLAAQVFDELGYKTRVSWNAMILGCTQNGSSEDAVRLFSRMQLENVKPDSFTLVSIIPALADISDPLQARWIHGYSIRLHLDQDVYVLTALIDMYAKCGRVSIARSLFNSARDRHVITWNAMIHGYGSHGSGKVAVELFEEMKSSGKVPNETTFLSVLSACSHAGLVDEGQEYFSSMKEDYGLEPGMEHYGTMVDLLGRAGKLHEAWSFIQKMPMEPGISVYGAML 705          

Query:  121 HTLSQRTHIPSHVYTHPAAILLELCTSIKELNQIIPLIIKNGLYNEHLFQTKLVSLFCNYGSPSEAFRVFETVEDKLEVFYHTLLKGYAKNSSLGDAMSFFCRMKSDGVRPVVYNFTYLLKVCGDNADLRRGKEIHAHLISSGFATNLFAMTAVVNMYAKCRQINEAYKMFDRMPERDLVSWNTIIAGYAQNGLAKIALELVIRMQEEGQKPDSITLVTLLPAVADYGSLIIGKSIHAYVLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSG 1713
            +TL +RT+IP H+Y HP A+LLELCTS+KEL+QIIP IIKNG Y+E LFQTKL+SLFCNYGS +EA RVFE +E+KLE  YHT+LKG+AKNSSL  A+ FFCRMK D VRPVVYNFTYLL +CGDN DLRRGKEIH  LI+SGF+ NLFAMTAVV++Y KCR I +AYKMFDRM ERDLV WNTII+GYAQNGL K+ALELV ++ EEG +PDS+T+V++LPAVAD  SL  GK+IHAYV+RA F+ LVNISTAL+DMYSKC S+GTAR+IF+ M  +T V+WNSMI G V+N D EEA  +F+KM+DEG QPT+VT+ME LHACAD GDLE+GKFVHKLV+ LKL S+VSVMNSL+SMYSKCK+VD AA +F+NL  +TLVSWN MILGYAQNGR++EAL+ FC+MQSQN+KPDSFTMVSVIPALAELS+ RQAKWIHGLVIR   D  +FVMTALVDMYAKCGA+HTARKLF+MM ERHV TWN+MID YGT+GLGK AV LF EM+KGTIKPND+TFLCV+SACSHSG
Sbjct:   30 NTLPRRTYIPGHIYKHPTAVLLELCTSVKELHQIIPSIIKNGFYSEELFQTKLISLFCNYGSLTEAARVFEPIENKLEALYHTMLKGFAKNSSLDSALLFFCRMKHDNVRPVVYNFTYLLTLCGDNFDLRRGKEIHGQLITSGFSWNLFAMTAVVSLYCKCRVIGDAYKMFDRMTERDLVCWNTIISGYAQNGLTKVALELVPKIFEEGHRPDSVTIVSVLPAVADIRSLRFGKAIHAYVIRAGFDWLVNISTALVDMYSKCDSLGTARVIFDGMGSRTVVTWNSMIAGCVENGDPEEAKVLFKKMMDEGLQPTDVTVMEVLHACADSGDLEQGKFVHKLVEDLKLDSNVSVMNSLISMYSKCKQVDFAANLFENLQNRTLVSWNAMILGYAQNGRLNEALNFFCEMQSQNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRLLDDTVFVMTALVDMYAKCGAIHTARKLFNMMSERHVITWNSMIDAYGTHGLGKEAVQLFVEMQKGTIKPNDVTFLCVLSACSHSG 560          

Query:  838 VLRASFESLVNISTALLDMYSKCGSVGTARLIFNRMKQKTAVSWNSMIDGYVQNEDAEEAMEIFQKMLDEGFQPTNVTIMEALHACADLGDLERGKFVHKLVDQLKLGSDVSVMNSLMSMYSKCKRVDIAAKIFKNLLGKTLVSWNTMILGYAQNGRVSEALSHFCQMQSQNMKPDSFTMVSVIPALAELSVTRQAKWIHGLVIRTCFDKNIFVMTALVDMYAKCGAVHTARKLFDMMDERHVTTWNAMIDGYGTNGLGKAAVDLFNEMEKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGQLSEAWDFIQKM 1857
            +++  F S     T L+ ++   GS+  A  +F  ++ K    +++M+ G+ +N   + A+  F +M  +  +P        L  C D  DL RGK +H  +       ++  M +++S+Y KC+ +  A K+F  +  + LV WNT+I GYAQNG    AL    ++  +  +PDS T+VSV+PA+A++   R  K IH  VIR  FD  + + TALVDMY+KC ++ TAR +FD M  R V TWN+MI G   NG  + A  LF +M    ++P D+T + V+ AC+ SG +E+G ++   + ED  L+  +    +++ +  +  Q+  A +  + +
Sbjct:   67 IIKNGFYSEELFQTKLISLFCNYGSLTEAARVFEPIENKLEALYHTMLKGFAKNSSLDSALLFFCRMKHDNVRPVVYNFTYLLTLCGDNFDLRRGKEIHGQLITSGFSWNLFAMTAVVSLYCKCRVIGDAYKMFDRMTERDLVCWNTIISGYAQNGLTKVALELVPKIFEEGHRPDSVTIVSVLPAVADIRSLRFGKAIHAYVIRAGFDWLVNISTALVDMYSKCDSLGTARVIFDGMGSRTVVTWNSMIAGCVENGDPEEAKVLFKKMMDEGLQPTDVTVMEVLHACADSGDLEQG-KFVHKLVEDLKLDSNVSVMNSLISMYSKCKQVDFAANLFENL 405