ppa003441m, ppa003441m (mRNA) Prunus persica

Query:  118 GKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            G   G   STS KAIQ+ICQPTDYK+ C ++L+   +N +DPKELV+  FQVAI Q+   ++NSTTL++L KD R   AL+NC EL++YAIDDL +SF+KLG FD +K+D YVEDLK+WLS A+TY++TCLDGF+NTTGDAG KM+  LK++ ELTSNGLAM+ E+S++   L I    RRLL                     +  R+L    ATP T+KP+V+V++ G GKYKTINEAL +IPKN     FV+YVKEGVY E V F K MTNVMLIGDGPTKT I+G  N+ DG            G  F+AKD+GFEN AGA  HQAVALRV SD++IFYNC MDGYQDTLY   HRQFYRDCTI+GTIDFIFGD+A VFQNC ++VRKPL+NQ C+VTA GR + R P+ ++LQNCTIS    Y   K   K+YLGRPW + +R I+MQSQIDD+I+PEGW+ W G    NTC++ E+GNRG  +  + RVTW G+K++T +   DFT G+FI G  W+  SGVPY + MM
Sbjct:   33 GTVAGGGISTSVKAIQAICQPTDYKEACVNSLTSAKANTSDPKELVRTAFQVAINQISSALQNSTTLRDLEKDPRTKGALENCHELMDYAIDDLRNSFNKLGVFDISKIDDYVEDLKIWLSGALTYQETCLDGFENTTGDAGEKMKALLKSAGELTSNGLAMIDEISSVLTNLQIPGISRRLL---------------------VGQRKL--FQATPDTIKPNVIVAQDGSGKYKTINEALVEIPKNGNT-TFVLYVKEGVYKEQVNFTKSMTNVMLIGDGPTKTTISGSLNFIDGIGTFRTATVAAVGSNFMAKDIGFENNAGASKHQAVALRVGSDMAIFYNCRMDGYQDTLYVHAHRQFYRDCTITGTIDFIFGDSAVVFQNCLILVRKPLDNQQCIVTAQGRNERREPTGIVLQNCTISAADDYIPFKTKFKSYLGRPWKAFSRTIIMQSQIDDLISPEGWLPWMGDFGLNTCFYAEYGNRGPASATTSRVTWRGIKQITGQHVNDFTVGRFISGHLWLGASGVPYTSDMM 543          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRH-KGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKT-GRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELN--KAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            KKK+AIIG                        G +  ++ S+S KAIQ+ICQPTDYK  C ++L+  A N TDPK+LV+A F  A+  L    KNST L+EL KD RA+QALQNC++L+ YAIDDL  SF+++G FD++K+D+ + D+K+WLSA +TY++TCLDGF+NTTGDAG KMRQ LKTS EL+SNGLA+V EVS++   L +    RRLL D     D +        P W  +    L  A    LKP++ V+K G G +KTINEA++ +PK +  + F++Y+K+G+Y+E V  +K  TN+M++GDGPTKT ITG  N+ DG            GD FIAK +GFEN+AGA  HQAVALRVQSD SIFYNC MDGYQDTLYT T RQFYRDCTISGTIDFIFGDAA +FQNC  +VRKPL+NQ C+VTA GR + R PSA+I+QN T + +  Y    N  K+YLGRPW   +R I+M+S I+D+I P GW+ W G     TC++ EF NRG GA+   RV W G+K + P  A DF  G+F+ GDRWI  +GVPY +G+ T
Sbjct:   13 KKKLAIIGFSSIFLVAMVIAVIASVSSSSSDSGNAQKQEISSSMKAIQAICQPTDYKDACVNSLTSKAGNTTDPKDLVQAAFASAMEHLSAAAKNSTLLQELNKDPRASQALQNCEDLVNYAIDDLKKSFNQVGDFDYSKMDNIIADIKIWLSAVITYQETCLDGFENTTGDAGEKMRQILKTSMELSSNGLAIVGEVSSILSNLQLANLNRRLLSDDPADPDNHIDDE---FPYWSHSEGRKLLQANVSELKPNLTVAKDGSGDFKTINEAIRQLPKFSN-QTFILYIKKGIYEEQVQINKTFTNLMMVGDGPTKTKITGSLNFVDGTPTFKTATVAVLGDGFIAKGIGFENSAGAAKHQAVALRVQSDRSIFYNCQMDGYQDTLYTHTKRQFYRDCTISGTIDFIFGDAAVIFQNCTFVVRKPLDNQQCIVTAQGRKERRQPSAIIIQNSTFTADPEYYPYRNELKSYLGRPWKEFSRTIIMESYIEDLIQPSGWLPWAGDFALRTCFYTEFRNRGPGAKTHDRVKWRGIKTIKPSHAIDFAPGRFLSGDRWIPSTGVPYNSGLFT 576          

Query:  112 HKGKSGGEQT--STSTKAIQSICQPTDYKKTCEDNLSKVASNVT-DPKELVKAGFQVAIGQLREVIKNSTTLKELAKDS-RANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK----TGRRLLQDAATATDENRFQRAKIIPAWID--NRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLT-PEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            HK   G ++   ST+TKA+ +IC PTDYK+ C  +   +A+N +  PK+ + A   + + +++E I  S ++      S R   A ++C++LL+ AI +L  SF  +G      ++   +DLK WLSA ++Y+Q+C+DGF  T     A     L  +Q LTSN LA+VSE+S +  + NI     +  R LQ+A   +D+         P+W    +R+L L       + P+ VV+  G G+YK+I  AL   PKN   + +VIYVK G+YDE++  +K++ N+ + GDGP KT++TG+K++ DG            G+ FI K +GF NTAG  GHQAVALRVQSD S F+NC MDGYQDTLY Q HRQFYR+C ISGT+DFIFGD+  + QN  +IVRKPL+NQ   +TAHGR + R  + L++QNC I  E      +    +YLGRPW + +R +VM+S + D I P GW+ W G    +T ++ E+ N+G GA  ++RV W G K +T   +A  FTAG FI G+ W+  +G PY  G  T
Sbjct:   33 HKSTDGDDEKVLSTTTKAVAAICSPTDYKQQCISSFQTLANNHSATPKDFLMAAIDITMKEVKEAIGKSESIGLAGNSSGRQKMATEDCQDLLQLAIGELQASFSMVGDAAMHTINDRAQDLKNWLSAVISYQQSCMDGFDETPEVKSAIQNGLLNATQ-LTSNALAIVSEISAILTSFNIPLNFTSSFRRLQEATEESDQ--------YPSWFSAADRKL-LGRVDNGKVTPNAVVALDGSGQYKSIGAALAAYPKNLNGR-YVIYVKAGIYDEYITIEKNLVNIFMYGDGPRKTMVTGKKSFLDGITTYKTSTFSVIGNGFICKSMGFRNTAGPEGHQAVALRVQSDYSAFFNCRMDGYQDTLYVQAHRQFYRNCVISGTVDFIFGDSTTLIQNSLIIVRKPLDNQQNTITAHGRAEKRETTGLVIQNCRIVPEEKLFPTRFKTPSYLGRPWKAYSRTVVMESTMGDFIHPAGWLPWMGNFALDTLYYAEYANKGPGANTAQRVKWKGYKVITNRNEALQFTAGPFIQGNEWLRLTGAPYFLGFRT 569          

Query:  115 KGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSK-VASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELA--KDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNR-RLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            K K+ G   STS KA+   C  T Y  +C ++L+  V S+   P++L     +VA+ +L    +  +  +      D     AL +C ELL+ AID+L  S         + LD++ +DLK WLSAA TY++TC++GF++  G+  + + +FLK S E +SN LA+++E+S L  +++ +    L +D               +P W+  + R  L +++ L  K D VV+  G GKYKTI+EALK +P  ++ K FVIYVK+GVY+E+V  +K   NV++IGDG  KTV++G+ N+ DG            G  F+A+++GF NTAGAI HQAVAL   +D ++FY C +D +QD+LY  +HRQFYR+C I GT+DFIFG++A VFQNC ++ ++P+  Q   +TA G+ D    + + +QNCTI      D    K YLGRPW + +  + M S +  +I P GW+ WTGT   NT ++ EF N G G+    RV W G++ +T ++A+ FT   FI G +WI  +GV +  G+
Sbjct:   56 KSKNAGNSVSTSIKAV---CDVTLYPDSCYNSLAPMVKSSQLKPEDLFNMSMEVALNELHRTFQRFSEHEGFKGITDKMLAGALDDCYELLDLAIDNLNSSLS-------SSLDNF-DDLKTWLSAAGTYQETCINGFES--GNLRSSVLEFLKNSTEFSSNSLAIITEISKLAGSISSRRLMGLPEDK--------------VPKWLSAKDRKLLQSSSTLKKKADAVVATDGSGKYKTISEALKAVPDKSK-KSFVIYVKKGVYNENVRVEKSKWNVLMIGDGMNKTVVSGKLNFVDGTPTFSTATFAVFGKGFVAREMGFRNTAGAIKHQAVALMSSADQTVFYRCLIDAFQDSLYAHSHRQFYRECDIYGTVDFIFGNSAVVFQNCNILPKQPMPGQQNTITAQGKNDPNQNTGIAIQNCTILPSA--DLSSVKTYLGRPWKNYSTTVYMHSMMGSLIDPAGWLPWTGTTAPNTIFYSEFQNFGPGSSTKNRVKWKGLRNITQKEASKFTVKSFIDGSKWISDAGVSFKPGL 561          

Query:  202 EDNLSKVASN-VTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKL----GPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNK--AYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKL-TPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            E NL  + S  +  P     +  +  I  LR  +   +   ++  D R + A+ +C ELL++A DDL  S   +    G  + T       DLK WLS+  T + TC++GF  T G     + + L     L  + L MV + +   K+     G + +                  P+W+      L  A+  ++ PDV V+  G G Y T+ +A++  P  ++   +VIY+K+G+Y E+V   K   N+M++GDG   TVITG ++Y DG            G  FIA+D+ FENTAG   HQAVALR  SDLS++Y C+M GYQDTLY  T+RQFYR+C ISGT+DFIFGDA  VFQNC+++V+K L NQ   +TA GR D   P+   +Q   IS +      +N   +YLGRPW   +R I+M+S I D I PEGW+EW G    +T ++GE+ N G  A L  RV W G   L    QAA+FT  +FI G+ W+  +GV Y AG+
Sbjct:   33 EANLKLLQSQCLAVPSSAFISSLKSTIDVLRGTMSVVSQFTKVFNDFRLSNAISDCLELLDFAADDLSWSLSAIQNPKGKDNGT--GDLGSDLKTWLSSTFTNQDTCIEGFVGTNGIVKTVVAESLSQVASLVHSLLTMVHDPAPKGKSNGGGGGVKHVGSGD-------------FPSWVGKHSRKLLQAS--SVSPDVTVAADGTGNYTTVMDAVQAAPDYSQ-NHYVIYIKQGIYRENVEIKKKKWNLMMVGDGMGATVITGNRSYIDGWTTYASATFAVKGKGFIARDMTFENTAGPEKHQAVALRSDSDLSVYYRCSMRGYQDTLYPHTNRQFYRECRISGTVDFIFGDATVVFQNCQILVKKGLPNQKNTITAQGRKDPAQPTGFSIQFSNISADSDLLASVNSTLSYLGRPWKQYSRTIIMKSYISDAIRPEGWLEWNGDFALDTLYYGEYMNYGPSAGLGSRVQWPGFHLLNNSAQAANFTVTEFIAGNLWLPSTGVKYSAGL 525          

Query:  124 SGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNV--TDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVE-DLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTL-FKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAAD-FTAGKFIFGDRWILPSGVPYVAGM 1710
            S  +Q  T    I   C   +   +C  ++     ++    P  ++ A  +  + + R  ++  T    L+   R   A+++CKELL++++ +L  S  ++        +   E +LK WLSAA++ + TCL+GF+ T     + +R  LK   +L SN LAM  ++ +L FK     T +   QD                P W+ +   DL  A P  +  D +VS  G G Y++I +A+ + P  +  + ++IYVK+GVY E++   K  T +M++GDG   TV+TG +N+  G            G  FIA+D+ F NTAG    Q VALRV SD S FY C+M+GYQDTLY  + RQFYR+C I GTIDFIFG+ AAV QNCK+  RKPL  Q   +TA GR   +SP     Q+   S +  Y       YLGRPW   +R + + + +  ++ P GW+EW G     T ++GE+ N G GA LS RV W G  K+     A+ FT G+FI G  W+  +GV + AG+
Sbjct:   59 SSKDQNQTLQALIIQACAKVENYSSCVSSIHNELESMGPRSPSSILTAALKTTLNEARIAVQMVTRFNALSSSYREQIAIEDCKELLDFSVSELAWSLLEMKSIRAGSTNVQSEGNLKAWLSAALSNQDTCLEGFEGTDRRIESFIRGSLKQVTQLISNVLAMYVQLHSLPFKPPRNSTEKSPSQD---------------FPKWMTDGDKDLLLAHPNQMGVDTIVSLDGSGHYRSIAQAIYEAPSYSNRR-YIIYVKKGVYKENIDMKKKKTKIMIVGDGIGATVVTGNRNFMQGWTTFRTATVAVSGKGFIARDITFRNTAGPKNFQGVALRVDSDQSAFYRCSMEGYQDTLYAHSLRQFYRECDIHGTIDFIFGNGAAVLQNCKIFTRKPLPLQKVTITAQGR---KSPD----QSTGFSIQDSYVYATQPTYLGRPWKQYSRTVFLNTYMSSLVQPRGWLEWNGNFALGTLYYGEYRNYGPGALLSGRVQWPGYHKIQDTSVANFFTVGRFIDGLSWLPSTGVRFSAGL 569          

Query:  172 CQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLR---EVIKNSTTLKELAKDSRANQ-ALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTG---RRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATP-------------LTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVK--VFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKA--YLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            C+ T Y K C   LS   S+   P    +   +  + Q R   E+I +  T  +    S A   AL +C++L E  +D L     +L   +    D  VE ++  LS  +T +QTC DG  ++     A +   L  + +L S  L +VS   +  +    + G    R L++     D  R   +KII   +    L+ +  +              + +   V VS  G   + TI +A+   P ++ ++   FVIYVKEG Y+E+    K+   +ML+GDG  +TVITG ++  DG            G+ F+A D+ F NTAG   HQAVA+R  +DLS FY C+ +GYQDTLY  + RQFYRDC + GT+DFIFG++A +FQNC +  RKP+ NQ    TA GR+D    + + + NCTI        +LN    YLGRPW   +R + MQS I  +I P GW+EW GT   +T ++GEF N G GA  S RV W G   +   QA +FT   F  GD W+    +P+  G++
Sbjct:   36 CKATLYPKLCRSILSTFRSSPVRPDAYGQFSVKQCLKQARRMSELIGHYLTHNQRWPMSHAEAGALDDCRQLSELNVDYLQTISGELKSAELMT-DELVERVRTLLSGIVTNQQTCYDGLVDSRNSMVAALLAPLSNANQLYSVSLGLVSRALSQTRKRRKRRGLTENRFLKE----LDRVREPTSKIIEV-LKKGSLNTSRGSSRGGRILAELVDGGVLVSNTVTVSPNGTDNFTTIADAISFAPNSSNIEDGYFVIYVKEGYYEEYPMVPKYKKGIMLLGDGINRTVITGNRSVVDGWTTFNSATFAVSGERFVAIDITFRNTAGPEKHQAVAVRNNADLSTFYRCSFEGYQDTLYAHSLRQFYRDCIVYGTVDFIFGNSACIFQNCNLYARKPMPNQKNAFTAQGRMDPNQNTGISIHNCTIEAAPDLAMDLNSTLNYLGRPWKQYSRTVYMQSYIGSLIDPVGWLEWNGTVGLDTLYYGEFENYGPGANTSMRVQWPGYTLMNASQAVNFTVYNFTMGDTWLTNLDIPFYGGLL 567          

Query:  457 EDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPK--NNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTI--SGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLT-PEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            +D + WLS+A+   +TCLDG +   G A A M +          N    +SE   L+                  TD  +  +  + P+      + LA  +P T K D+VV+K G G + TINEA+  + +  +   +  V+YVK G+Y+E V   K++ NVM +GDG  KT+IT  +N  DG            GD F AKD+ FEN AG   HQAVA+RV SDLS+FY C+  GYQDTLY  ++RQF+RDC + GTIDFIFG+AA VFQNC + VRKP+  Q+ M+TA GR     P+ + +Q   +  S E    K   K++LGRPW   +R + +++ +D +I P GW EW+G    +T ++GE+ N G GA   +RV W G   L   E A  FT  +FI G++WI  SGVP+  G+
Sbjct:   88 DDARTWLSSALASHRTCLDGLEGK-GMAEAPMAR----------NVTVWLSEALALYAKYK-----------EPDTDAEKEVQPTLKPS---QNEVMLAEWSPKTSKADIVVAKDGSGNHMTINEAVAALTRMVHKRTRRVVVYVKSGIYNEKVEIGKNLNNVMFVGDGVDKTIITADRNVHDGATTPSSATFGVSGDGFWAKDITFENRAGPHKHQAVAMRVSSDLSVFYRCSFKGYQDTLYVHSNRQFFRDCHVYGTIDFIFGNAAVVFQNCDIYVRKPMNRQSNMITAQGRDIPEEPTGISVQASRVLSSPEFTTVKGSFKSFLGRPWKRYSRTVFLETDLDGLIDPRGWTEWSGNYGLSTLYYGEYNNSGGGASTKERVKWPGFHVLNGTEDAMPFTVSRFIQGEKWIPASGVPFSPGI 485          

Query:  142 STSTKAIQSICQPTDYKKTCEDNL-SKVASNVTD-PKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKEL----LEYAIDD--LGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVK--VFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTI--SGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            S+++ A  SICQ T    +C+  + S  ++NV D  +  +K     +   L  V K  +    L+  + A +ALQ+C+ L    L+Y +    + D+  K+     + L++  +D++  LSA +T +QTCLDG Q T+     K             NG++   +   L+++L+    R+LL    T  D+                         +++   V V++ G G + TIN+A+   P N +     FVIY++ GVY+E+V   K+   +M+IGDG  +TVITG ++  DG               F+A ++ F NTAGA  HQAVALR  +DLS FY C+ + YQDTLYT + RQFYR+C I GT+DFIFG+AA VFQNC +  R PL  Q   +TA GR D    +   + NC I  + +        K YLGRPW   +R + MQS +  +I P GW  W+G    +T ++ E+ N G G+  S RVTWSG   + P  AA+FT G F+ G  W+  +GVPY  G++
Sbjct:   83 SSTSLADDSICQSTPDPSSCKGLVQSNKSANVYDYGRSSLKKSIATSRKFLSLVDKYLSARSNLS--AAAVRALQDCRFLGGLNLDYLLSSSQVADANSKI----LSVLEA--DDVQTLLSALLTNQQTCLDGLQETSSSWSVK-------------NGVSTPLQNRKLYESLS---NRKLLD---TGNDQ-------------------------VSISDIVTVNQDGSGNFATINDAIAVAPNNTDGSNGYFVIYIQAGVYEEYVSIAKNKKYLMMIGDGINQTVITGNRSVVDGWTTFNSATFAVVAQGFVAVNITFRNTAGAAKHQAVALRSGADLSTFYLCSFEAYQDTLYTHSLRQFYRECDIYGTVDFIFGNAAVVFQNCNLYPRLPLSGQFNAITAQGRTDPNQNTGTSIHNCVIRAADDLAASNGTTKTYLGRPWKEYSRTVYMQSNMGSLINPSGWSIWSGDFALSTLYYAEYNNTGPGSNTSNRVTWSGYHVIGPSDAANFTVGNFLLGGDWLPQTGVPYTGGLL 566          

Query:  274 AIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLT-PEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            ++  L+ V++ +  +     D R   AL +C EL++ ++  + DS + LG      +DS+  D   WLS  +T   TC DG     G +   M + LK         LAM+  VS                    A ++         P W+D+R   +  ++   +K +VVV+K G G YKT+ EA+  +P N++ + +VI+VK+G Y E+V       NVM++GDG   TVITG  N  DG            GD FIA+D+ F+NTAG   HQAVALRV +D ++   C +D YQDTLY  T+RQFYRDC I+GT+DFIFG+AA VFQNCK++ RKP++ QA MVTA GR +    +   +QNC I      +  K   K+YLGRPW   +RA+V+QS I D I P GW                           KRV W G + +T P +A +FT  + I G  W+  +GV Y  G+
Sbjct:   74 SMSHLQGVMEMTVDVNRRMNDPRDQAALSDCVELMDLSMGRIRDSVEALGR---GTVDSHA-DAHAWLSGVLTNYITCTDGIN---GPSRISMERGLKHLISRAETSLAMLVAVSP-------------------AKEDVLQPLHSEFPPWVDSRDRKILESSSKDIKANVVVAKDGSGNYKTVKEAIASVPNNSKTR-YVIHVKKGTYKENVEIVTKQKNVMIVGDGMDSTVITGSLNVIDGSTTFKSATLAAVGDGFIAQDIWFQNTAGPQKHQAVALRVGADQAVINRCRIDAYQDTLYAHTNRQFYRDCYITGTVDFIFGNAAVVFQNCKLVARKPMDKQANMVTAQGRTNPYQNTGTSIQNCNIIASSDLEPVKGTIKSYLGRPWKEYSRAVVLQSYIGDHIDPAGWSV-------------------------KRVKWPGYRVITSPAEARNFTVAELIQGGTWLESTGVAYTEGL 503          

Query:  130 GEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            G   STS KAIQ+ICQPTDYK+ C ++L+   +N +DPKELV+  FQVAI Q+   ++NSTTL++L KD R   AL+NC EL++YAIDDL +SF+KLG FD +K+D YVEDLK+WLS A+TY++TCLDGF+NTTGDAG KM+  LK++ ELTSNGLAM+ E+S++   L I    RRLL D  +   E R     + P+W    +  L  ATP T+KP+V+V++ G GKYKTINEAL +IPKN     FV+YVKEGVY E V F K MTNVMLIGDGPTKT I+G  N+ DG            G  F+AKD+GFEN AGA  HQAVALRV SD++IFYNC MDGYQDTLY   HRQFYRDCTI+GTIDFIFGD+A VFQNC ++VRKPL+NQ C+VTA GR + R P+ ++LQNCTIS    Y   K   K+YLGRPW + +R I+MQSQIDD+I+PEGW+ W G    NTC++ E+GNRG  +  + RVTW G+K++T +   DFT G+FI G  W+  SGVPY + MM
Sbjct:   55 GGGISTSVKAIQAICQPTDYKEACVNSLTSAKANTSDPKELVRTAFQVAINQISSALQNSTTLRDLEKDPRTKGALENCHELMDYAIDDLRNSFNKLGVFDISKIDDYVEDLKIWLSGALTYQETCLDGFENTTGDAGEKMKALLKSAGELTSNGLAMIDEISSVLTNLQIPGISRRLLSD-ESGKGEYRSDEGGLYPSWASVGQRKLFQATPDTIKPNVIVAQDGSGKYKTINEALVEIPKNGNT-TFVLYVKEGVYKEQVNFTKSMTNVMLIGDGPTKTTISGSLNFIDGIGTFRTATVAAVGSNFMAKDIGFENNAGASKHQAVALRVGSDMAIFYNCRMDGYQDTLYVHAHRQFYRDCTITGTIDFIFGDSAVVFQNCLILVRKPLDNQQCIVTAQGRNERREPTGIVLQNCTISAADDYIPFKTKFKSYLGRPWKAFSRTIIMQSQIDDLISPEGWLPWMGDFGLNTCFYAEYGNRGPASATTSRVTWRGIKQITGQHVNDFTVGRFISGHLWLGASGVPYTSDMM 583          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRHKG------KSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            KKK A+IG                    + KG           Q STSTK+IQ+ICQPTDYK+TCED+L+K A N +DP +LV+AGFQVAI  L+  I+NSTTLKE+AKD  A QAL NCKEL+  AI DL  SF ++G FD +KLD YV +LK+WLSA +TY+QTCLDGF NTTG AG KM++ L TS +LTSNGLAMV+ +S++ + L++   TGR+LL     A   + F      P+W+   +  L   TP T+KP++VV++ G G+YKTINEA+K+IPK+     FV+Y+KEGVY E V F + +T++MLIGDGPTKT ITG  ++A G            G +F+AKD+GFEN+AGA GHQA+AL+VQSD+S+FYNC +DGYQ+TL++ T+RQFYR+CTI+GTIDFI GDAAAVFQNCKM+VRKPLENQ C +TA GR + R P+  +LQNCTI+ E+ Y   K  + ++LGRPW   +R IVMQS IDD+I P+GW  W GT   +TC   E+GNRG GA L+ RVTW G+ KL+P+ A  FTAGKF+ GD WI  +GVPY +GMM
Sbjct:   17 KKKFAVIGVSSIILVAMVVAVAVGVNDGKEKGGESSPLSGSSGQLSTSTKSIQAICQPTDYKQTCEDSLNKAAGNTSDPHKLVQAGFQVAIDALKVAIENSTTLKEVAKDPMAKQALDNCKELMNTAISDLKTSFQQVGDFDISKLDEYVANLKIWLSATITYQQTCLDGFDNTTGPAGQKMKEILSTSSQLTSNGLAMVTGLSSILQDLDLSGLTGRKLL-----AQGNDNF------PSWLSPAKRRLLAQTPATIKPNMVVAQDGSGQYKTINEAIKNIPKSGN-STFVLYIKEGVYKEVVTFSRSLTHIMLIGDGPTKTKITGDLSFAGGVQIYKTATVSVSGSHFMAKDIGFENSAGATGHQAIALKVQSDMSVFYNCQIDGYQNTLFSHTYRQFYRECTITGTIDFISGDAAAVFQNCKMVVRKPLENQRCTITAQGRNNTREPTGFVLQNCTITAEKDYLPVKLDSPSFLGRPWKPYSRTIVMQSSIDDIIDPKGWAPWMGTFGIDTCSLSEYGNRGPGATLTSRVTWKGIVKLSPQDAEAFTAGKFLEGDSWIAATGVPYTSGMM 577          

Query:  136 QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDN-RRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            Q ST++K+I++ICQPTDY++TCE++LSK A N TDP +LV+AGF+V I  L+  I  STTLKELAKD  A+QAL NC+EL++ AI +L  SFD +  F  ++ D YV +LKVWLSA +TY++TCLDGF+NTTG AG KM++ L  S +LTSNGLAMV  V+++ K LNI   T RRLL+    A DE         P+W++  +R+ L   TP T+K D +V++ G G+YKTI EA++ IPK    + FVIY+KEGVY E V   +  T+V++IGDGPTKT ITG  NYA+G            GD+F+AKD+GFEN+AGAIGHQAVALRVQ+D+S+FYNC +DGYQDTLY  T RQFYRDCTI+GTIDFIFGDA AVFQNCK++VRKPL+NQ C+VTA GR + R P+  ++QNCTI+ +  Y   +  NKAYLGRPW  L+R IVMQS IDD+IAPEGW+ W G+   NT ++ E+ N+G GA  + RV W+G+KKLTPE A  +TA KFI GD WI  +GVPY AGM++
Sbjct:   52 QISTTSKSIKAICQPTDYRETCEESLSKAAGNTTDPSKLVQAGFKVTIEALQNAINRSTTLKELAKDPMASQALDNCRELMDDAIAELEHSFDLIESFQASQFDEYVNNLKVWLSATITYQRTCLDGFENTTGSAGEKMKELLMASSQLTSNGLAMVDGVTSILKDLNIPGLTSRRLLE----ADDE--------FPSWVNGGKRMLLLKETPATIKADAIVAQDGSGQYKTIAEAIEKIPKKKN-ETFVIYIKEGVYKEQVSLARSHTHVLMIGDGPTKTKITGNLNYANGVQTFKTATVSISGDHFMAKDIGFENSAGAIGHQAVALRVQADMSVFYNCQIDGYQDTLYAHTKRQFYRDCTITGTIDFIFGDAIAVFQNCKLVVRKPLDNQQCIVTAQGRNETREPTGFVIQNCTITADPQYFPVRLQNKAYLGRPWRELSRTIVMQSHIDDLIAPEGWLPWLGSFGLNTLFYSEYNNKGQGAVETNRVKWAGIKKLTPEAADGYTAAKFIQGDEWIPQTGVPYTAGMIS 570          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRH-KGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKT-GRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELN--KAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            KKK+AIIG                        G +  ++ S+S KAIQ+ICQPTDYK  C ++L+  A N TDPK+LV+A F  A+  L    KNST L+EL KD RA+QALQNC++L+ YAIDDL  SF+++G FD++K+D+ + D+K+WLSA +TY++TCLDGF+NTTGDAG KMRQ LKTS EL+SNGLA+V EVS++   L +    RRLL D     D +        P W  +    L  A    LKP++ V+K G G +KTINEA++ +PK +  + F++Y+K+G+Y+E V  +K  TN+M++GDGPTKT ITG  N+ DG            GD FIAK +GFEN+AGA  HQAVALRVQSD SIFYNC MDGYQDTLYT T RQFYRDCTISGTIDFIFGDAA +FQNC  +VRKPL+NQ C+VTA GR + R PSA+I+QN T + +  Y    N  K+YLGRPW   +R I+M+S I+D+I P GW+ W G     TC++ EF NRG GA+   RV W G+K + P  A DF  G+F+ GDRWI  +GVPY +G+ T
Sbjct:   13 KKKLAIIGFSSIFLVAMVIAVIASVSSSSSDSGNAQKQEISSSMKAIQAICQPTDYKDACVNSLTSKAGNTTDPKDLVQAAFASAMEHLSAAAKNSTLLQELNKDPRASQALQNCEDLVNYAIDDLKKSFNQVGDFDYSKMDNIIADIKIWLSAVITYQETCLDGFENTTGDAGEKMRQILKTSMELSSNGLAIVGEVSSILSNLQLANLNRRLLSDDPADPDNHIDDE---FPYWSHSEGRKLLQANVSELKPNLTVAKDGSGDFKTINEAIRQLPKFSN-QTFILYIKKGIYEEQVQINKTFTNLMMVGDGPTKTKITGSLNFVDGTPTFKTATVAVLGDGFIAKGIGFENSAGAAKHQAVALRVQSDRSIFYNCQMDGYQDTLYTHTKRQFYRDCTISGTIDFIFGDAAVIFQNCTFVVRKPLDNQQCIVTAQGRKERRQPSAIIIQNSTFTADPEYYPYRNELKSYLGRPWKEFSRTIIMESYIEDLIQPSGWLPWAGDFALRTCFYTEFRNRGPGAKTHDRVKWRGIKTIKPSHAIDFAPGRFLSGDRWIPSTGVPYNSGLFT 576          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            HK K    + S S KAI+++CQPT YK+TCE +L+K A N TDPKEL+K  F++A  Q+    K S TL EL KD R   AL +CKEL+  +I++L  S +K+  FDF++LD  + D+K WLSAA+TYE+TCLD F+NTT +AG KM++ LKT+ E++SNGL +VS +S++   L I    RRLLQD           +A   PAWID     L +A P  +KPD+VV+K G G YKTI EAL  IPK +  + FV+Y+KEG+Y+E+V F++ MTN+++IGDGP KT ITG KN+ DG            GD F+A+++GFEN+AGAI HQAVALRV SD ++FYNC+MDGYQDTLYT   RQFYRDCT+SGTIDF+FGDA  VFQNC  +VRKPLENQ C+VTA GR   R PSA+I+QN TI+     +  K+  K+YLGRPW   +R I+M++ IDD+I PEGW  W G+    TCW+GE+ N G G+++  RV W+G+K ++ + A DFT G+F+ GD WI P+GVPY
Sbjct:   51 HKSK----EVSASMKAIKTLCQPTYYKQTCERSLAKSAGNTTDPKELIKIAFKLAEKQIDSASKKSLTLLELEKDPRTRGALNSCKELMTMSINELRSSLEKVADFDFSQLDELMADIKTWLSAAITYEETCLDAFENTTTNAGEKMKKALKTAMEMSSNGLDIVSGISSVLTDLQIPGVSRRLLQDDIPVAGHGDISQA--FPAWIDPGTRRLLSAPPSNIKPDLVVAKDGSGDYKTILEALPQIPKKSN-ETFVLYIKEGIYEEYVEFNRSMTNLVVIGDGPDKTRITGSKNFVDGINTYRTATVAVIGDNFVARNIGFENSAGAIKHQAVALRVSSDYAVFYNCSMDGYQDTLYTHAKRQFYRDCTVSGTIDFVFGDAPVVFQNCTFLVRKPLENQQCIVTAQGRKARRQPSAIIIQNSTITAHPELEPVKDQYKSYLGRPWKEFSRTIIMETFIDDLIQPEGWSPWFGSFGLKTCWYGEYNNYGPGSDMKNRVKWNGIKPVSRQHAIDFTPGRFLRGDSWIKPTGVPY 575          

Query:  112 HKGKSGGE-QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +K  +GGE + +TS KAI+ +C PTDYK+TCED L K A N +DP ELVK  F   + Q+ +V K S T+ EL KD R   AL  CKEL++YAI +L  SF++LG F+F K+D  +  L++WLSA +++EQTCLDGFQ T G+AG  +++ LKT+ +LT NGLAMVSE+S     + I     RRLL                  P+W+D R   L  A    +K D+VV++ G G+YKTINEAL  +PK      FV+++K G+Y E+V  ++ MT+++ IGDGP KTVI+G K+Y DG            GD+FIAK++GFENTAGAI HQAVA+RV SD SIFYNC  DGYQDTLY  +HRQFYRDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  +LQ CTI GE  Y   KE +KAYLGRPW   +R I+M + I D I PEGW  W G    NT ++ E  N G GA ++KRVTW G+KKL+ E+   FT  ++I GD WI   GVPY+ G+ TG
Sbjct:   39 NKSDNGGEGEITTSVKAIKDVCAPTDYKETCEDTLRKDAKNTSDPLELVKTAFNATMKQISDVAKKSQTMIELQKDPRTKMALDQCKELMDYAIGELSKSFEELGRFEFHKVDEALIKLRIWLSATISHEQTCLDGFQGTQGNAGETIKKALKTAVQLTHNGLAMVSEMSNYLGQMQIPEMNSRRLLSQE--------------FPSWMDGRARRLLNAPMSEVKLDIVVAQDGSGQYKTINEALNYVPKKKNT-TFVVHIKAGIYKEYVQVNRSMTHLVFIGDGPEKTVISGSKSYKDGITTYKTATVAIVGDHFIAKNIGFENTAGAIKHQAVAIRVLSDESIFYNCKFDGYQDTLYAHSHRQFYRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLLNQACPITAHGRKDPRESTGFVLQGCTIVGEPDYLAVKENSKAYLGRPWKEYSRTIIMNTFIPDFIPPEGWQPWLGDFGLNTLFYSEVQNTGPGAPITKRVTWPGIKKLSEEEILTFTPAQYIQGDAWIPGKGVPYIPGLFTG 564          

Query:  109 RHKGKSGGE-QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNR--RLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            ++ G S G+ + + S KA++ +C PTDY+KTCED L K   N TDP ELVK  F V + Q+ +  K S T+ EL KD R   AL  CKEL++YA+ +L +SF++LG F+F  LD  + +L++WLSAA+++E+TCL+GFQ T G+AG  M++ LKT+ ELT NGLA++SE+S     + I     RRLL +                P+W+D R  +L  A A    +KPD+VV++ G G+Y TINEAL+ +PK      FV+++K G+Y E+V  +K MT+++ IGDGP KT+I+G KNY DG            G+YFIAK++GFENTAGAI HQAVALRVQSD SIF+NC  DGYQDTLYT +HRQF+RDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  + Q CTI+GE  Y   KE +KAYLGRPW   +R I+M + I D + P+GW  W G     T ++ E  N G G+ L+ RVTW+G+K L+ E    FT  ++I GD W+   GVPY  G++ G
Sbjct:   40 KNDGDSEGKGEITASVKAVKDVCAPTDYRKTCEDTLIKNGKNTTDPMELVKTAFSVTMKQITDAAKKSQTMMELQKDPRTRMALDQCKELMDYALGELSNSFEELGKFEFHLLDEALINLRIWLSAAISHEETCLEGFQGTQGNAGETMKKALKTAIELTHNGLAIISEMSNFVGQMQIPGLNSRRLLAEG--------------FPSWLDQRGRKLLQAAAAYSDVKPDIVVAQDGSGQYTTINEALQFVPKKKNT-TFVVHIKAGLYKEYVQVNKSMTHLVFIGDGPDKTIISGNKNYKDGITTYRTATVAIVGNYFIAKNIGFENTAGAIKHQAVALRVQSDESIFFNCRFDGYQDTLYTHSHRQFFRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLPNQACPITAHGRKDPREVTGFVFQGCTIAGEPDYLAVKETSKAYLGRPWKEYSRTIIMNTFIPDFVQPQGWQPWLGDFGLKTLFYSEVQNTGPGSALANRVTWAGIKTLSDEDILKFTPAQYIQGDTWVPGKGVPYTPGLLAG 568          

Query:  136 QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            Q S S KA+++ICQPTDY+KTCE+NL K A N TDP+EL+K  F++A   + E  K S  L+EL+KD R   ALQ+C+EL+  ++D+L  S +K+  FD T+++  + D+K WLSA++TY++TCLDGFQNTT +AG +M++ LK S EL++N LA+VS +S+   +L     RRLLQD             +I P W D  +  L  A    +K D+VV+K G G + TI +AL  +P  +  K FV+Y+K G+Y E++ F+K MTN+M+IGDG   T I G KN+ DG            GD F+AK++GFEN AGAI HQAVALRV +D ++FYNC+MDG+QDT+YT   RQFYRDC+ISGTIDF+FGDA+AVFQNCK ++RKPLENQ C+VTA GR   R PSA+I+QN TI+       +++L K+YLGRPW   +R I+M+S IDDVI PEGW+ W GT    TCW+ EF N G G+  + RV W+G+K +  + A DFT G+F  G  WI  +G+PY
Sbjct:   54 QVSASMKAVKAICQPTDYRKTCEENLQKAAGNTTDPRELIKMAFKIAEKHVNEASKKSKVLEELSKDPRTRGALQSCRELMTMSVDELKQSLNKVTDFDITEIEKLMADVKTWLSASITYQETCLDGFQNTTTNAGKEMKKGLKLSMELSANLLAIVSGISSAIPSLESLGQRRLLQDDLPVLGHGD----QIFPTWTDFGKRRLLAAPASKIKADIVVAKDGSGDFSTIRDALHHVPIKSS-KTFVLYIKAGIYQEYIDFNKSMTNLMVIGDGRETTRIVGNKNFVDGINTYHTATVVVLGDNFVAKNIGFENNAGAIKHQAVALRVSADYALFYNCSMDGHQDTMYTHAKRQFYRDCSISGTIDFVFGDASAVFQNCKFLIRKPLENQQCIVTAQGRKMRRQPSAIIIQNSTITAHPDLFPERKLFKSYLGRPWKEFSRTIIMESFIDDVIQPEGWLPWLGTFGLKTCWYTEFNNNGPGSSKAARVKWNGIKTIDRQHALDFTPGRFFKGGAWIKTTGIPY 571          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            HK  S   Q S S KA+++ICQPTDY+KTCE++L K A N TDPKEL+K  F++A  Q+ E  + S  L+EL+KD R   ALQ+CKEL+  ++ +L  S DK+  FD ++L+  + D+K WLSA++TY++TCLDGF+NTT DAG KM++ +K   EL++N L +VS +S+   +L   T RRLLQD     D          P W D     L  A    +K D+VV+K G G + TI EALK +P  ++ K FV+++K GVY E++   K M N+++IGDG   T I G KN+ DG            GD F+AK++GFEN AGAI HQAVALRV +D +IFYNC+MDG+QDTLYT   RQFYRDC+ISGTIDF+FGDA+AVFQNCK +VRKPLENQ C+VTA GR   R PSALI+Q+ TI+       +++  K+YLGRPW   +R I+M+S IDD+I PEGW+ W GT    TCW+ EF N G G+  + RV W+G+K +  + A DFT G+F+ GD WI  +G+PY
Sbjct:   49 HKSTS---QVSASVKAVKAICQPTDYRKTCEESLQKAAGNTTDPKELIKIAFKIAEKQINEASEKSKLLEELSKDPRTRGALQSCKELMNMSVGELKQSLDKVTDFDLSELEKMMADVKTWLSASITYQETCLDGFENTTTDAGKKMKKGMKLGMELSANLLDIVSGISSAIPSLESFTHRRLLQD-----DLPVLGHGDQFPTWTDFGTRRLLAAPVSKIKADIVVAKDGSGDFSTIREALKHVPIKSK-KAFVLHIKAGVYQEYLEISKGMINLVVIGDGKENTRIIGNKNFVDGINTFHTATVAVLGDNFVAKNIGFENNAGAIKHQAVALRVSADYAIFYNCSMDGHQDTLYTHAKRQFYRDCSISGTIDFVFGDASAVFQNCKFLVRKPLENQQCIVTAQGRKMRRQPSALIIQSSTITAHPDLFPERKQFKSYLGRPWKEYSRTIIMESFIDDLIQPEGWLPWLGTFGLKTCWYTEFNNYGPGSSKNLRVKWNGIKTINRQHAMDFTPGRFLKGDSWIKATGIPY 570          

Query:    7 GGEVQNKKKIAIIGXXXXXXXXXXXXXXXXXXXXRHKGKSGGEQTST------STKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKI-IPAWIDNR---RLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEW---TGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAG 1707
            GG+ +  K++AIIG                     +  K  GE+TS       S KA++++C PTDYKK CED+L   A N+T+PKEL+K  F + I ++ E +K +  L+E  KD R  QAL  CK++++ +ID+   S ++   FD   LD  +  LKVWLS A+TY++TCLD F+NTT DAG KM++ L+TS  ++SNGL++++++S  F+ +    GRRLL+++    ++         +P W+D+R   R  L   T   L+  VVV+K G G + TI EALK +PK N +K FVIY+KEGVY E+V   K MT+V+ IGDG  KT ITG KN+ DG            GD+F+   +GFEN+AG   HQAVALRVQSD SIFY C MDGYQDTLY  T RQFYRDC ISGTIDF+FGD+ AV QNC  +VRKPLENQ C+VTA GR +   P+ LI+Q  +I  +  Y   +  NKAYL RPW   +R I + + I D+I PEG+M W    G    +TC++GE+ NRG G+++ +RV W G+K +T E AA F   +F  GD WI  + VPY  G
Sbjct:    4 GGDAKRNKRLAIIGVSTFLLVAMVVAVTVNVGF--NNKKEPGEETSKESHVSQSVKAVKTLCAPTDYKKECEDSLIAHAGNITEPKELIKIAFNITIAKISEGLKKTHLLQEAEKDERTKQALDTCKQVMQLSIDEFQRSLERFSNFDLNSLDRVLTSLKVWLSGAITYQETCLDAFENTTTDAGKKMKEVLQTSMHMSSNGLSIINQLSKTFEEMKQPAGRRLLKESVDGEEDVLGHGGDFELPEWVDDRAGVRKLLNKMTGRKLQAHVVVAKDGSGNFTTITEALKHVPKKN-LKPFVIYIKEGVYKEYVEVTKTMTHVVFIGDGGRKTRITGNKNFIDGVGTFKTASVAITGDFFVGIGIGFENSAGPEKHQAVALRVQSDRSIFYKCRMDGYQDTLYAHTMRQFYRDCIISGTIDFVFGDSIAVLQNCTFVVRKPLENQQCIVTAQGRKEKNQPTGLIIQGGSIVADPKYYPVRLKNKAYLARPWKDFSRTIFLDTYIGDMITPEGYMPWQTPAGITGTDTCYYGEYNNRGPGSDVKQRVKWQGVKTITSEGAASFVPIRFFHGDDWIRVTRVPYSPG 582          

Query:  124 SGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +G E+ +TS KAI+ +C PTDYK+TCED L K A + +DP ELVK  F   + Q+ +V K S T+ EL KD RA  AL  CKEL++YAI +L  SF++LG F+F K+D  +  L++WLSA +++EQTCLDGFQ T G+AG  +++ LKT+ +LT NGLAMV+E+S     + I     RRLL                  P+W+D R   L  A    +KPD+VV++ G G+YKTINEAL  +PK      FV+++KEG+Y E+V  ++ MT+++ IGDGP KTVI+G K+Y DG            GD+FIAK++ FENTAGAI HQAVA+RV +D SIFYNC  DGYQDTLY  +HRQFYRDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  +LQ CTI GE  Y   KE +K YLGRPW   +R I+M + I D + PEGW  W G    NT ++ E  N G GA ++KRVTW G+KKL+ E+   FT  ++I GD WI   GVPY+ G+ +G
Sbjct:   45 AGDEEITTSVKAIKDVCAPTDYKETCEDTLRKDAKDTSDPLELVKTAFNATMKQISDVAKKSQTMIELQKDPRAKMALDQCKELMDYAIGELSKSFEELGKFEFHKVDEALVKLRIWLSATISHEQTCLDGFQGTQGNAGETIKKALKTAVQLTHNGLAMVTEMSNYLGQMQIPEMNSRRLLSQE--------------FPSWMDARARRLLNAPMSEVKPDIVVAQDGSGQYKTINEALNFVPKKKNT-TFVVHIKEGIYKEYVQVNRSMTHLVFIGDGPDKTVISGSKSYKDGITTYKTATVAIVGDHFIAKNIAFENTAGAIKHQAVAIRVLADESIFYNCKFDGYQDTLYAHSHRQFYRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLLNQACPITAHGRKDPRESTGFVLQGCTIVGEPDYLAVKEQSKTYLGRPWKEYSRTIIMNTFIPDFVPPEGWQPWLGEFGLNTLFYSEVQNTGPGAAITKRVTWPGIKKLSDEEILKFTPAQYIQGDAWIPGKGVPYILGLFSG 565          

Query:  109 RHKGKSGGE-QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNR--RLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +H G S G+ + + S KA++ +C PTDY+KTCED L K   N TDP ELVK  F V + Q+ +  K S T+ EL KDSR   AL  CKEL++YA+D+L +SF++LG F+F  LD  + +L++WLSAA+++E+TCL+GFQ T G+AG  M++ LKT+ ELT NGLA++SE+S     + I     RRLL +                P+W+D R  +L  A A    +KPD+VV++ G G+YKTINEAL+ +PK      FV+++K G+Y E+V  +K M++++ IGDGP KT+I+G KNY DG            G+YFIAK++GFENTAGAI HQAVA+RVQSD SIF+NC  DGYQDTLYT +HRQF+RDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  + Q CTI+GE  Y   KE +KAYLGRPW   +R I+M + I D + P+GW  W G     T ++ E  N G G+ L+ RVTW+G+K L+ E    FT  ++I GD WI   GVPY  G++ G
Sbjct:   40 KHDGDSKGKAEVNASVKAVKDVCAPTDYRKTCEDTLIKNGKNTTDPMELVKTAFNVTMKQITDAAKKSQTIMELQKDSRTRMALDQCKELMDYALDELSNSFEELGKFEFHLLDEALINLRIWLSAAISHEETCLEGFQGTQGNAGETMKKALKTAIELTHNGLAIISEMSNFVGQMQIPGLNSRRLLAEG--------------FPSWVDQRGRKLLQAAAAYSDVKPDIVVAQDGSGQYKTINEALQFVPKKRNT-TFVVHIKAGLYKEYVQVNKTMSHLVFIGDGPDKTIISGNKNYKDGITTYRTATVAIVGNYFIAKNIGFENTAGAIKHQAVAVRVQSDESIFFNCRFDGYQDTLYTHSHRQFFRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLPNQACPITAHGRKDPRESTGFVFQGCTIAGEPDYLAVKETSKAYLGRPWKEYSRTIIMNTFIPDFVQPQGWQPWLGDFGLKTLFYSEVQNTGPGSALANRVTWAGIKTLSEEDILKFTPAQYIQGDDWIPGKGVPYTTGLLAG 568          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTT--LKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKI-----IPAWI--DNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXX-GDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYV 1701
            H  K    Q  T+T A++++C PTDYK+TC ++L K + + T P +L+K GF V I  + + IK ++     + A D     AL+ C++L+  A DDL    D    F   +++ +VEDL+VWLS ++ Y+QTC+D F+ T       M++  KTS+ELTSNGLAM++ +S L    N+              D  ++ R  +     IP+W+  + RRL    AT   +K +VVV+  G G+YKTINEAL  +PK N+ K FVIY+K+GVY+E V   K MT+V  IGDGPTKT ITG  NY  G             GD F AK++GFENTAG  GHQAVALRV +DL++FYNC +DGYQDTLY  +HRQF+RDCT+SGT+DFIFGD   V QNC ++VRKP+++Q+CM+TA GR D R  + L+LQNC I+GE  Y   K +NKAYLGRPW   +R I+M + IDDVI P GW+ W G    NT ++ E+ N G G+  ++RV W G+KKL+P+QA  FT  +F+ G+ WI P+ VPY+
Sbjct:   39 HSEKIVPVQIKTATTAVEAVCAPTDYKETCVNSLMKASPDSTQPLDLIKLGFNVTIRSIEDSIKKASVELTAKAANDKDTKGALELCEKLMNDATDDLKKCLDNFDGFSIPQIEDFVEDLRVWLSGSIAYQQTCMDTFEETNSKLSQDMQKIFKTSRELTSNGLAMITNISNLLGEFNV---------TGVTGDLGKYARKLLSAEDGIPSWVGPNTRRL---MATKGGVKANVVVAHDGSGQYKTINEALNAVPKANQ-KPFVIYIKQGVYNEKVDVTKKMTHVTFIGDGPTKTKITGSLNYYIGKVKTYLTATVAINGDNFTAKNIGFENTAGPEGHQAVALRVSADLAVFYNCQIDGYQDTLYVHSHRQFFRDCTVSGTVDFIFGDGIVVLQNCNIVVRKPMKSQSCMITAQGRSDKRESTGLVLQNCHITGEPAYIPVKSINKAYLGRPWKEFSRTIIMGTTIDDVIDPAGWLPWNGDFALNTLYYAEYENNGPGSNQAQRVKWPGIKKLSPKQALRFTPARFLRGNLWIPPNRVPYM 567          

Query:  109 RHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVI-KNSTTLKELA-KDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWI--DNRRLDLATAT-PLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXX-GDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVA 1704
            +H  K        +TKA+Q++C PTD+K TC ++L   + +  DP +L+K GF+V I  + E + K S  +K  A K+  A  A + C++L+  AIDDL    D    F   +++ +VEDL+VWLS ++ ++QTC+D F     +    M +  KTS+EL+SN LAMV+ +STL    N+ TG   L  A              IP W+  + RRL  A    P  +K + VV++ G G++KTI +AL  +PK N+V  F+I++KEG+Y E V   K M +V  IGDGP KT+ITG  N+  G             GD+F AK++G ENTAG  G QAVALRV +D ++F++C +DG+QDTLY  +HRQFYRDCT+SGT+DFIFGDA  + QNCK++VRKP + Q CMVTA GR ++R  + L+L  C I+G+  Y   K +NKAYLGRPW   +R I+M++ IDDVI P GW+ W+G     T ++ E  N G G+  ++RV W G+KKLTP+ A  +T  +F+ GD WI  + VPY A
Sbjct:   34 KHSPKDDENHIRKTTKAVQAVCAPTDFKDTCVNSLMGASPDSDDPVDLIKLGFKVTIKSINESLEKASGDIKAKADKNPEAKGAFELCEKLMIDAIDDLKKCMDH--GFSVDQIEVFVEDLRVWLSGSIAFQQTCMDSFGEIKSNLMQDMLKIFKTSRELSSNSLAMVTRISTLIPNSNL-TG---LTGALAKYARKLLSTEDSIPTWVGPEARRLMAAQGGGPGPVKANAVVAQDGTGQFKTITDALNAVPKGNKVP-FIIHIKEGIYKEKVTVTKKMPHVTFIGDGPNKTLITGSLNFGIGKVKTFLTATITIEGDHFTAKNIGIENTAGPEGGQAVALRVSADYAVFHSCQIDGHQDTLYVHSHRQFYRDCTVSGTVDFIFGDAKCILQNCKIVVRKPNKGQTCMVTAQGRSNVRESTGLVLHGCHITGDPAYIPMKSVNKAYLGRPWKEFSRTIIMKTTIDDVIDPAGWLPWSGDFALKTLYYAEHMNTGPGSNQAQRVKWPGIKKLTPQDALLYTGDRFLRGDTWIPQTQVPYTA 566          

Query:  355 LQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK---TGRRLLQDAATATDENRFQRAKIIPAWI-DNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNK-AYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFI------FGDRWILPSGVPYVAGMM 1713
            ++ C E+L+YA+D +  S   L  FDF KL  Y  DLKVWL+  ++++QTCLDGF NTT  AG  M + LKTS EL+SN + M+  VS + K  +       RRLL D               IP+W+ D  R  LA      ++P+ VV++ G G++KT+ +ALK +P  N V  FVI+VK GVY E V   K M  V +IGDGPTKT  TG  NYADG            G  F+AKD+GFENTAG   HQAVALRV +D +IFYNC MDG+QDTLY Q+ RQFYRDC+ISGTIDF+FG+   VFQNCK++ R P + Q C+VTA GR    S SAL+ Q+   +GE        K +YLGRPW   ++ ++M S ID +  PEG+M W G+A   TC + E+ N+G GA+ + RV W G+K LT   AA++  GKF         D WI+ SGVPY  G M
Sbjct:    1 MEICNEVLDYAVDGIHKSVGTLDQFDFHKLSEYAFDLKVWLTGTLSHQQTCLDGFANTTTKAGETMTKVLKTSMELSSNAIDMMDAVSRILKGFDTSQYSVSRRLLSDDG-------------IPSWVNDGHRRLLAGGN---VQPNAVVAQDGSGQFKTLTDALKTVPPKNAVP-FVIHVKAGVYKETVNVAKEMNYVTVIGDGPTKTKFTGSLNYADGINTYNTATFGVNGANFMAKDIGFENTAGTGKHQAVALRVTADQAIFYNCQMDGFQDTLYVQSQRQFYRDCSISGTIDFVFGERFGVFQNCKLVCRLPAKGQQCLVTAGGREKQNSASALVFQSSHFTGEPALTSVTPKVSYLGRPWKQYSKVVIMDSTIDAIFVPEGYMPWMGSAFKETCTYYEYNNKGPGADTNLRVKWHGVKVLTSNVAAEYYPGKFFEIVNATARDTWIVKSGVPYSLGPM 447          

Query:  154 KAIQSICQPTDYKKTCEDNL---SKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPL-TLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGT-ANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            K IQ++C  T YK TC++ L   +K  +  TDP+ L+K+        L +V K   +LK   KD +   A+  CK L++ A ++LG S  ++   +       V DL  WLSA M+Y++TC+DGF+   G    ++R+   +SQ LTSN LAM+  +     ++  K   RLL +A ++  E        I +W+ N+   +  A  +  LKP+  V+K G G + TIN ALK +P   + + + IY+K G+YDE V  DK   NV ++GDG  KT++TG K++A              G+ F+A+ +GF NTAG  GHQAVA+RVQSD S+F NC  +GYQDTLY  THRQ+YR C I GT+DFIFGDAAA+FQNC + +RK L  Q   VTA GR+D    +  ++ NCT++        K   K+YLGRPW   +R +VM+S I+DVI P GW+ W  T    +T  + E+ N G     + RV W G + L  E+A  FT G F+ G+ WI   G P   G+
Sbjct:   93 KIIQTLCNSTLYKPTCQNTLKNETKKDTPQTDPRSLLKSAIVAVNDDLDQVFKRVLSLKTENKDDK--DAIAQCKLLVDEAKEELGTSMKRINDSEVNNFAKIVPDLDSWLSAVMSYQETCVDGFEE--GKLKTEIRKNFNSSQVLTSNSLAMIKSLDGYLSSVP-KVKTRLLLEARSSAKETDH-----ITSWLSNKERRMLKAVDVKALKPNATVAKDGSGNFTTINAALKAMPAKYQGR-YTIYIKHGIYDESVIIDKKKPNVTMVGDGSQKTIVTGNKSHAKKIRTFLTATFVAQGEGFMAQSMGFRNTAGPEGHQAVAIRVQSDRSVFLNCRFEGYQDTLYAYTHRQYYRSCVIIGTVDFIFGDAAAIFQNCDIFIRKGLPGQKNTVTAQGRVDKFQTTGFVIHNCTVAPNEDLKPVKAQFKSYLGRPWKPHSRTVVMESTIEDVIDPVGWLRWQETDFAIDTLSYAEYKNDGPSGATAARVKWPGFRVLNKEEAMKFTVGPFLQGE-WIQAIGSPVKLGL 606          

Query:  154 KAIQSICQPTDYKKTCEDNLSKVASN---VTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWI--DNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGT-ANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            K IQ++C  T Y + CE  L         + +P   +K+  +     L  V++   +LK   +D +   A++ CK L+E A ++   S +K+   +    +  V DL+ WLSA M+Y++TCLDGF+   G+  ++++  + +SQ LTSN LA++   +     +     R LL D               IP+W+  D+RR+ L       LKP+  V+K G G + TIN+AL+ +P+  E + ++IYVK+G+YDE+V  DK   N+ ++GDG  KT++TG K++A              G+ F+A+ +GF NTAG  GHQAVA+RVQSD SIF NC  +GYQDTLY  THRQ+YR C I GTIDFIFGDAAA+FQNC + +RK L  Q   VTA GR+D    +  ++ NC I+        KE  K+YLGRPW + +R I+M+S+I++VI P GW+ W  T    +T ++ E+ N+G   + + RV W G K +  E+A ++T G F+ GD WI  SG P   G+
Sbjct:  107 KIIQTLCSSTLYMQICEKTLKNRTDKGFALDNPTTFLKSAIEAVNEDLDLVLEKVLSLKTENQDDK--DAIEQCKLLVEDAKEETVASLNKINVTEVNSFEKVVPDLESWLSAVMSYQETCLDGFEE--GNLKSEVKTSVNSSQVLTSNSLALIKTFTENLSPVMKVVERHLLDD---------------IPSWVSNDDRRM-LRAVDVKALKPNATVAKDGSGDFTTINDALRAMPEKYEGR-YIIYVKQGIYDEYVTVDKKKANLTMVGDGSQKTIVTGNKSHAKKIRTFLTATFVAQGEGFMAQSMGFRNTAGPEGHQAVAIRVQSDRSIFLNCRFEGYQDTLYAYTHRQYYRSCVIVGTIDFIFGDAAAIFQNCNIFIRKGLPGQKNTVTAQGRVDKFQTTGFVVHNCKIAANEDLKPVKEEYKSYLGRPWKNYSRTIIMESKIENVIDPVGWLRWQETDFAIDTLYYAEYNNKGSSGDTTSRVKWPGFKVINKEEALNYTVGPFLQGD-WISASGSPVKLGL 611          

Query:  145 TSTKAIQSICQPTDYKKTCEDNLSKV-ASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKL--DSYVEDLKVWLSAAMTYEQTCLDGF----QNTTGDAGAKMRQFLKT----SQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEW-TGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKK-LTPEQAADFTAGKFIFGDRWILPSGV 1692
            T + ++++IC  T + ++C  ++SK+ +SN TDP+ L K   +V I +L  +      L +  +D R   AL+ C +L+E A+D L D+   +   +  K    S +EDLK WLSA +T  +TC D      QN T  A + + Q LK+    S E TSN LA+VS++ +    L I   RR           +  Q++     W   R L  A      LKPDV V+  G G   T+NEA+  +PK + +K+FVIYVK G Y E+V  DK   NVM+ GDG  KT+I+G KN+ DG            G  FI KD+G  NTAGA  HQAVA R  SD S++Y C+ DG+QDTLY  ++RQFYRDC ++GTIDFIFG AA VFQ CK++ R+PL NQ   +TA G+ D    S + +Q CTIS        +   YLGRPW   +  ++M++ I  V+ P GWM W +G     +  +GE+ N G G+++++RV W+G K  ++  +AA FT    + G  WI  +GV
Sbjct:   68 TPSTSLKAICSVTRFPESCISSISKLPSSNTTDPETLFKLSLKVIIDELDSISDLPEKLSKETEDERIKSALRVCGDLIEDALDRLNDTVSAIDDEEKKKTLSSSKIEDLKTWLSATVTDHETCFDSLDELKQNKTEYANSTITQNLKSAMSRSTEFTSNSLAIVSKILSALSDLGIPIHRR------RRLMSHHHQQSVDFEKWARRRLLQTAG-----LKPDVTVAGDGTGDVLTVNEAVAKVPKKS-LKMFVIYVKSGTYVENVVMDKSKWNVMIYGDGKGKTIISGSKNFVDGTPTYETATFAIQGKGFIMKDIGIINTAGAAKHQAVAFRSGSDFSVYYQCSFDGFQDTLYPHSNRQFYRDCDVTGTIDFIFGSAAVVFQGCKIMPRQPLSNQFNTITAQGKKDPNQSSGMSIQRCTISAN---GNVIAPTYLGRPWKEFSTTVIMETVIGAVVRPSGWMSWVSGVDPPASIVYGEYKNTGPGSDVTQRVKWAGYKPVMSDAEAAKFTVATLLHGADWIPATGV 581          

Query:  124 SGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVAS-NVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            + G+  S S KA+   C  T +K+ C + L    + +  +P+EL +   ++ I    EV K          D + N  +  C ELL+  ID+L ++       D T +   V+DL+ WLS+A TY++TC++         G      LK S ELTSN LA+++ +  +  A + K  RRLL  A    D +  +R              L  +T L    D+VV+K G GKY+TI  AL+D+P+ +E +  +IYVK+GVY E+V  +K M NV+++GDG +K++++GR N  DG            G  F+A+D+GF NTAG   HQAVAL V +DL+ FY C M+ YQDTLY    RQFYR+CTI GT+DFIFG++A+V Q+C+++ R+P++ Q   +TA GR D    + + +  C IS        +   +LGRPW + +  ++M S +   I  +GW+ WTG +  +T ++GE+ N G GA    RV W G++ L+ ++A  FT   FI G RW+  + VP+ +G+
Sbjct:   61 NNGDSISVSVKAV---CDVTLHKEKCFETLGSAPNASSLNPEELFRYAVKITIA---EVSKAINAFSSSLGDEKNNITMNACAELLDLTIDNLNNTLTSSSNGDVT-VPELVDDLRTWLSSAGTYQRTCVETLAPDMRPFG---ESHLKNSTELTSNALAIITWLGKI--ADSFKLRRRLLTTADVEVDFHAGRR--------------LLQSTDLRKVADIVVAKDGSGKYRTIKRALQDVPEKSEKRT-IIYVKKGVYFENVKVEKKMWNVIVVGDGESKSIVSGRLNVIDGTPTFKTATFAVFGKGFMARDMGFINTAGPSKHQAVALMVSADLTAFYRCTMNAYQDTLYVHAQRQFYRECTIIGTVDFIFGNSASVLQSCRILPRRPMKGQQNTITAQGRTDPNMNTGISIHRCNISPLGDLTDVM--TFLGRPWKNFSTTVIMDSYLHGFIDRKGWLPWTGDSAPDTIFYGEYKNTGPGASTKNRVKWKGLRFLSTKEANRFTVKPFIDGGRWLPATKVPFRSGL 561          

Query:  136 QTSTSTKA-IQSICQPTDYKKTCEDNLSKVA-SNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSY-VEDLKVWLSAAMTYEQTCLD--GFQNTTGDAGA--KMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELN-KAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTAN-HNTCWFGEFGNRGVGAELSKRVTWSGMK-KLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            QT  S  A ++++C  T Y  +C  ++S +  SN TDP+ L K   +VAI +L           E  +D+R  +A+  C  +   A+D L DS   LG        S  V +++ WLSAA+T + TCLD  G  N+T   GA  ++   ++ S E  SN LA+V+++  L          R L                  P W+      L         PD VV+K G G++KTI EALK + K +E + F +YVKEG Y E++  DK+  NVM+ GDG  KT + G +N+ DG            G  FIAKD+GF N AGA  HQAVALR  SD S+F+ C+ DG+QDTLY  ++RQFYRDC I+GTIDFIFG+AA VFQ+CK++ R+PL NQ   +TA G+ D    + +I+Q  TI+    +   L    YLGRPW   +  ++MQS I  ++ P GWM W        T ++ E+ N G GA++S+RV W+G K  +T   A +FT   FI G  W+  + V +
Sbjct:   68 QTELSPAASLKAVCDTTRYPSSCFSSISSLPESNTTDPELLFKLSLRVAIDELSSFPSKLRANAE--QDARLQKAIDVCSSVFGDALDRLNDSISALGTVAGRIASSASVSNVETWLSAALTDQDTCLDAVGELNSTAARGALQEIETAMRNSTEFASNSLAIVTKILGLLSRFETPIHHRRLLG---------------FPEWLGAAERRLLEEKNNDSTPDAVVAKDGSGQFKTIGEALKLVKKKSEER-FSVYVKEGRYVENIDLDKNTWNVMIYGDGKDKTFVVGSRNFMDGTPTFETATFAVKGKGFIAKDIGFVNNAGASKHQAVALRSGSDRSVFFRCSFDGFQDTLYAHSNRQFYRDCDITGTIDFIFGNAAVVFQSCKIMPRQPLPNQFNTITAQGKKDPNQNTGIIIQKSTIT---PFGNNLTAPTYLGRPWKDFSTTVIMQSDIGALLNPVGWMSWVPNVEPPTTIFYAEYQNSGPGADVSQRVKWAGYKPTITDRNAEEFTVQSFIQGPEWLPNAAVQF 577          

Query:  124 SGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +G E+ +TS KAI+ +C PTDYK+TCED L K A + +DP ELVK  F   + Q+ +V K S T+ EL KD RA  AL  CKEL++YAI +L  SF++LG F+F K+D  +  L++WLSA +++EQTCLDGFQ T G+AG  +++ LKT+ +LT NGLAMV+E+S     + I     RRLL                  P+W+D R   L  A    +KPD+VV++ G G+YKTINEAL  +PK      FV+++KEG+Y E+V  ++ MT+++ IGDGP KTVI+G K+Y DG            GD+FIAK++ FENTAGAI HQAVA+RV +D SIFYNC  DGYQDTLY  +HRQFYRDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  +LQ CTI GE  Y   KE +K YLGRPW   +R I+M + I D + PEGW  W G    NT ++ E  N G GA ++KRVTW G+KKL+ E+   FT  ++I GD WI   GVPY+ G+ +G
Sbjct:   45 AGDEEITTSVKAIKDVCAPTDYKETCEDTLRKDAKDTSDPLELVKTAFNATMKQISDVAKKSQTMIELQKDPRAKMALDQCKELMDYAIGELSKSFEELGKFEFHKVDEALVKLRIWLSATISHEQTCLDGFQGTQGNAGETIKKALKTAVQLTHNGLAMVTEMSNYLGQMQIPEMNSRRLLSQE--------------FPSWMDARARRLLNAPMSEVKPDIVVAQDGSGQYKTINEALNFVPKKKNT-TFVVHIKEGIYKEYVQVNRSMTHLVFIGDGPDKTVISGSKSYKDGITTYKTATVAIVGDHFIAKNIAFENTAGAIKHQAVAIRVLADESIFYNCKFDGYQDTLYAHSHRQFYRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLLNQACPITAHGRKDPRESTGFVLQGCTIVGEPDYLAVKEQSKTYLGRPWKEYSRTIIMNTFIPDFVPPEGWQPWLGEFGLNTLFYSEVQNTGPGAAITKRVTWPGIKKLSDEEILKFTPAQYIQGDAWIPGKGVPYILGLFSG 565          

Query:  109 RHKGKSGGE-QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNR--RLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +H G S G+ + + S KA++ +C PTDY+KTCED L K   N TDP ELVK  F V + Q+ +  K S T+ EL KDSR   AL  CKEL++YA+D+L +SF++LG F+F  LD  + +L++WLSAA+++E+TCL+GFQ T G+AG  M++ LKT+ ELT NGLA++SE+S     + I     RRLL +                P+W+D R  +L  A A    +KPD+VV++ G G+YKTINEAL+ +PK      FV+++K G+Y E+V  +K M++++ IGDGP KT+I+G KNY DG            G+YFIAK++GFENTAGAI HQAVA+RVQSD SIF+NC  DGYQDTLYT +HRQF+RDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  + Q CTI+GE  Y   KE +KAYLGRPW   +R I+M + I D + P+GW  W G     T ++ E  N G G+ L+ RVTW+G+K L+ E    FT  ++I GD WI   GVPY  G++ G
Sbjct:   40 KHDGDSKGKAEVNASVKAVKDVCAPTDYRKTCEDTLIKNGKNTTDPMELVKTAFNVTMKQITDAAKKSQTIMELQKDSRTRMALDQCKELMDYALDELSNSFEELGKFEFHLLDEALINLRIWLSAAISHEETCLEGFQGTQGNAGETMKKALKTAIELTHNGLAIISEMSNFVGQMQIPGLNSRRLLAEG--------------FPSWVDQRGRKLLQAAAAYSDVKPDIVVAQDGSGQYKTINEALQFVPKKRNT-TFVVHIKAGLYKEYVQVNKTMSHLVFIGDGPDKTIISGNKNYKDGITTYRTATVAIVGNYFIAKNIGFENTAGAIKHQAVAVRVQSDESIFFNCRFDGYQDTLYTHSHRQFFRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLPNQACPITAHGRKDPRESTGFVFQGCTIAGEPDYLAVKETSKAYLGRPWKEYSRTIIMNTFIPDFVQPQGWQPWLGDFGLKTLFYSEVQNTGPGSALANRVTWAGIKTLSEEDILKFTPAQYIQGDDWIPGKGVPYTTGLLAG 568          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTT--LKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKI-----IPAWI--DNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXX-GDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYV 1701
            H  K    Q  T+T A++++C PTDYK+TC ++L K + + T P +L+K GF V I  + + IK ++     + A D     AL+ C++L+  A DDL    D    F   +++ +VEDL+VWLS ++ Y+QTC+D F+ T       M++  KTS+ELTSNGLAM++ +S L    N+              D  ++ R  +     IP+W+  + RRL    AT   +K +VVV+  G G+YKTINEAL  +PK N+ K FVIY+K+GVY+E V   K MT+V  IGDGPTKT ITG  NY  G             GD F AK++GFENTAG  GHQAVALRV +DL++FYNC +DGYQDTLY  +HRQF+RDCT+SGT+DFIFGD   V QNC ++VRKP+++Q+CM+TA GR D R  + L+LQNC I+GE  Y   K +NKAYLGRPW   +R I+M + IDDVI P GW+ W G    NT ++ E+ N G G+  ++RV W G+KKL+P+QA  FT  +F+ G+ WI P+ VPY+
Sbjct:   39 HSEKIVPVQIKTATTAVEAVCAPTDYKETCVNSLMKASPDSTQPLDLIKLGFNVTIRSIEDSIKKASVELTAKAANDKDTKGALELCEKLMNDATDDLKKCLDNFDGFSIPQIEDFVEDLRVWLSGSIAYQQTCMDTFEETNSKLSQDMQKIFKTSRELTSNGLAMITNISNLLGEFNV---------TGVTGDLGKYARKLLSAEDGIPSWVGPNTRRL---MATKGGVKANVVVAHDGSGQYKTINEALNAVPKANQ-KPFVIYIKQGVYNEKVDVTKKMTHVTFIGDGPTKTKITGSLNYYIGKVKTYLTATVAINGDNFTAKNIGFENTAGPEGHQAVALRVSADLAVFYNCQIDGYQDTLYVHSHRQFFRDCTVSGTVDFIFGDGIVVLQNCNIVVRKPMKSQSCMITAQGRSDKRESTGLVLQNCHITGEPAYIPVKSINKAYLGRPWKEFSRTIIMGTTIDDVIDPAGWLPWNGDFALNTLYYAEYENNGPGSNQAQRVKWPGIKKLSPKQALRFTPARFLRGNLWIPPNRVPYM 567          

Query:  109 RHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVI-KNSTTLKELA-KDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWI--DNRRLDLATAT-PLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXX-GDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVA 1704
            +H  K        +TKA+Q++C PTD+K TC ++L   + +  DP +L+K GF+V I  + E + K S  +K  A K+  A  A + C++L+  AIDDL    D    F   +++ +VEDL+VWLS ++ ++QTC+D F     +    M +  KTS+EL+SN LAMV+ +STL    N+ TG   L  A              IP W+  + RRL  A    P  +K + VV++ G G++KTI +AL  +PK N+V  F+I++KEG+Y E V   K M +V  IGDGP KT+ITG  N+  G             GD+F AK++G ENTAG  G QAVALRV +D ++F++C +DG+QDTLY  +HRQFYRDCT+SGT+DFIFGDA  + QNCK++VRKP + Q CMVTA GR ++R  + L+L  C I+G+  Y   K +NKAYLGRPW   +R I+M++ IDDVI P GW+ W+G     T ++ E  N G G+  ++RV W G+KKLTP+ A  +T  +F+ GD WI  + VPY A
Sbjct:   34 KHSPKDDENHIRKTTKAVQAVCAPTDFKDTCVNSLMGASPDSDDPVDLIKLGFKVTIKSINESLEKASGDIKAKADKNPEAKGAFELCEKLMIDAIDDLKKCMDH--GFSVDQIEVFVEDLRVWLSGSIAFQQTCMDSFGEIKSNLMQDMLKIFKTSRELSSNSLAMVTRISTLIPNSNL-TG---LTGALAKYARKLLSTEDSIPTWVGPEARRLMAAQGGGPGPVKANAVVAQDGTGQFKTITDALNAVPKGNKVP-FIIHIKEGIYKEKVTVTKKMPHVTFIGDGPNKTLITGSLNFGIGKVKTFLTATITIEGDHFTAKNIGIENTAGPEGGQAVALRVSADYAVFHSCQIDGHQDTLYVHSHRQFYRDCTVSGTVDFIFGDAKCILQNCKIVVRKPNKGQTCMVTAQGRSNVRESTGLVLHGCHITGDPAYIPMKSVNKAYLGRPWKEFSRTIIMKTTIDDVIDPAGWLPWSGDFALKTLYYAEHMNTGPGSNQAQRVKWPGIKKLTPQDALLYTGDRFLRGDTWIPQTQVPYTA 566          

Query:  154 KAIQSICQPTDYKKTCEDNL---SKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPL-TLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGT-ANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            K IQ++C  T YK TC++ L   +K  +  TDP+ L+K+        L +V K   +LK   KD +   A+  CK L++ A ++LG S  ++   +       V DL  WLSA M+Y++TC+DGF+   G    ++R+   +SQ LTSN LAM+  +     ++  K   RLL +A ++  E        I +W+ N+   +  A  +  LKP+  V+K G G + TIN ALK +P   + + + IY+K G+YDE V  DK   NV ++GDG  KT++TG K++A              G+ F+A+ +GF NTAG  GHQAVA+RVQSD S+F NC  +GYQDTLY  THRQ+YR C I GT+DFIFGDAAA+FQNC + +RK L  Q   VTA GR+D    +  ++ NCT++        K   K+YLGRPW   +R +VM+S I+DVI P GW+ W  T    +T  + E+ N G     + RV W G + L  E+A  FT G F+ G+ WI   G P   G+
Sbjct:   93 KIIQTLCNSTLYKPTCQNTLKNETKKDTPQTDPRSLLKSAIVAVNDDLDQVFKRVLSLKTENKDDK--DAIAQCKLLVDEAKEELGTSMKRINDSEVNNFAKIVPDLDSWLSAVMSYQETCVDGFEE--GKLKTEIRKNFNSSQVLTSNSLAMIKSLDGYLSSVP-KVKTRLLLEARSSAKETDH-----ITSWLSNKERRMLKAVDVKALKPNATVAKDGSGNFTTINAALKAMPAKYQGR-YTIYIKHGIYDESVIIDKKKPNVTMVGDGSQKTIVTGNKSHAKKIRTFLTATFVAQGEGFMAQSMGFRNTAGPEGHQAVAIRVQSDRSVFLNCRFEGYQDTLYAYTHRQYYRSCVIIGTVDFIFGDAAAIFQNCDIFIRKGLPGQKNTVTAQGRVDKFQTTGFVIHNCTVAPNEDLKPVKAQFKSYLGRPWKPHSRTVVMESTIEDVIDPVGWLRWQETDFAIDTLSYAEYKNDGPSGATAARVKWPGFRVLNKEEAMKFTVGPFLQGE-WIQAIGSPVKLGL 606          

Query:  154 KAIQSICQPTDYKKTCEDNLSKVASN---VTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWI--DNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGT-ANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            K IQ++C  T Y + CE  L         + +P   +K+  +     L  V++   +LK   +D +   A++ CK L+E A ++   S +K+   +    +  V DL+ WLSA M+Y++TCLDGF+   G+  ++++  + +SQ LTSN LA++   +     +     R LL D               IP+W+  D+RR+ L       LKP+  V+K G G + TIN+AL+ +P+  E + ++IYVK+G+YDE+V  DK   N+ ++GDG  KT++TG K++A              G+ F+A+ +GF NTAG  GHQAVA+RVQSD SIF NC  +GYQDTLY  THRQ+YR C I GTIDFIFGDAAA+FQNC + +RK L  Q   VTA GR+D    +  ++ NC I+        KE  K+YLGRPW + +R I+M+S+I++VI P GW+ W  T    +T ++ E+ N+G   + + RV W G K +  E+A ++T G F+ GD WI  SG P   G+
Sbjct:  107 KIIQTLCSSTLYMQICEKTLKNRTDKGFALDNPTTFLKSAIEAVNEDLDLVLEKVLSLKTENQDDK--DAIEQCKLLVEDAKEETVASLNKINVTEVNSFEKVVPDLESWLSAVMSYQETCLDGFEE--GNLKSEVKTSVNSSQVLTSNSLALIKTFTENLSPVMKVVERHLLDD---------------IPSWVSNDDRRM-LRAVDVKALKPNATVAKDGSGDFTTINDALRAMPEKYEGR-YIIYVKQGIYDEYVTVDKKKANLTMVGDGSQKTIVTGNKSHAKKIRTFLTATFVAQGEGFMAQSMGFRNTAGPEGHQAVAIRVQSDRSIFLNCRFEGYQDTLYAYTHRQYYRSCVIVGTIDFIFGDAAAIFQNCNIFIRKGLPGQKNTVTAQGRVDKFQTTGFVVHNCKIAANEDLKPVKEEYKSYLGRPWKNYSRTIIMESKIENVIDPVGWLRWQETDFAIDTLYYAEYNNKGSSGDTTSRVKWPGFKVINKEEALNYTVGPFLQGD-WISASGSPVKLGL 611          

Query:  145 TSTKAIQSICQPTDYKKTCEDNLSKV-ASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKL--DSYVEDLKVWLSAAMTYEQTCLDGF----QNTTGDAGAKMRQFLKT----SQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEW-TGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKK-LTPEQAADFTAGKFIFGDRWILPSGV 1692
            T + ++++IC  T + ++C  ++SK+ +SN TDP+ L K   +V I +L  +      L +  +D R   AL+ C +L+E A+D L D+   +   +  K    S +EDLK WLSA +T  +TC D      QN T  A + + Q LK+    S E TSN LA+VS++ +    L I   RR           +  Q++     W   R L  A      LKPDV V+  G G   T+NEA+  +PK + +K+FVIYVK G Y E+V  DK   NVM+ GDG  KT+I+G KN+ DG            G  FI KD+G  NTAGA  HQAVA R  SD S++Y C+ DG+QDTLY  ++RQFYRDC ++GTIDFIFG AA VFQ CK++ R+PL NQ   +TA G+ D    S + +Q CTIS        +   YLGRPW   +  ++M++ I  V+ P GWM W +G     +  +GE+ N G G+++++RV W+G K  ++  +AA FT    + G  WI  +GV
Sbjct:   68 TPSTSLKAICSVTRFPESCISSISKLPSSNTTDPETLFKLSLKVIIDELDSISDLPEKLSKETEDERIKSALRVCGDLIEDALDRLNDTVSAIDDEEKKKTLSSSKIEDLKTWLSATVTDHETCFDSLDELKQNKTEYANSTITQNLKSAMSRSTEFTSNSLAIVSKILSALSDLGIPIHRR------RRLMSHHHQQSVDFEKWARRRLLQTAG-----LKPDVTVAGDGTGDVLTVNEAVAKVPKKS-LKMFVIYVKSGTYVENVVMDKSKWNVMIYGDGKGKTIISGSKNFVDGTPTYETATFAIQGKGFIMKDIGIINTAGAAKHQAVAFRSGSDFSVYYQCSFDGFQDTLYPHSNRQFYRDCDVTGTIDFIFGSAAVVFQGCKIMPRQPLSNQFNTITAQGKKDPNQSSGMSIQRCTISAN---GNVIAPTYLGRPWKEFSTTVIMETVIGAVVRPSGWMSWVSGVDPPASIVYGEYKNTGPGSDVTQRVKWAGYKPVMSDAEAAKFTVATLLHGADWIPATGV 581          

Query:  124 SGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVAS-NVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            + G+  S S KA+   C  T +K+ C + L    + +  +P+EL +   ++ I    EV K          D + N  +  C ELL+  ID+L ++       D T +   V+DL+ WLS+A TY++TC++         G      LK S ELTSN LA+++ +  +  A + K  RRLL  A    D +  +R              L  +T L    D+VV+K G GKY+TI  AL+D+P+ +E +  +IYVK+GVY E+V  +K M NV+++GDG +K++++GR N  DG            G  F+A+D+GF NTAG   HQAVAL V +DL+ FY C M+ YQDTLY    RQFYR+CTI GT+DFIFG++A+V Q+C+++ R+P++ Q   +TA GR D    + + +  C IS        +   +LGRPW + +  ++M S +   I  +GW+ WTG +  +T ++GE+ N G GA    RV W G++ L+ ++A  FT   FI G RW+  + VP+ +G+
Sbjct:   61 NNGDSISVSVKAV---CDVTLHKEKCFETLGSAPNASSLNPEELFRYAVKITIA---EVSKAINAFSSSLGDEKNNITMNACAELLDLTIDNLNNTLTSSSNGDVT-VPELVDDLRTWLSSAGTYQRTCVETLAPDMRPFG---ESHLKNSTELTSNALAIITWLGKI--ADSFKLRRRLLTTADVEVDFHAGRR--------------LLQSTDLRKVADIVVAKDGSGKYRTIKRALQDVPEKSEKRT-IIYVKKGVYFENVKVEKKMWNVIVVGDGESKSIVSGRLNVIDGTPTFKTATFAVFGKGFMARDMGFINTAGPSKHQAVALMVSADLTAFYRCTMNAYQDTLYVHAQRQFYRECTIIGTVDFIFGNSASVLQSCRILPRRPMKGQQNTITAQGRTDPNMNTGISIHRCNISPLGDLTDVM--TFLGRPWKNFSTTVIMDSYLHGFIDRKGWLPWTGDSAPDTIFYGEYKNTGPGASTKNRVKWKGLRFLSTKEANRFTVKPFIDGGRWLPATKVPFRSGL 561          

Query:  718 PAWIDNRRLDLATATPLT--LKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYA-DGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVA 1704
            P W+      L    P    +K +VVV+K G GK KTI +AL  +P  N  K FVI++KEGVY E V   K M +VM +GDGPTKTVITG   +  D             GDYF+AKD+GFENTAGA  HQAVALRV +D ++F+NC+M+GYQDTLY  THRQFYR+C +SGTIDF+FGDA AVFQNC+ ++R+P+E+Q C+VTA GR D R  + +++ N  I+G+  Y   K  N+A+LGRPW   +R I+M ++IDDVI PEGW++W  T   NT ++ E+ NRG G+   +RV W G+K+++   A +F  G F+ G+ WI  + +PY A
Sbjct:  368 PPWVTPHSRRLLARRPRNNGIKANVVVAKDGSGKCKTIAQALAMVPMKN-TKKFVIHIKEGVYKEKVEVTKKMLHVMFVGDGPTKTVITGDIAFLPDQVGTYRTASVAVNGDYFMAKDIGFENTAGAARHQAVALRVSADFAVFFNCHMNGYQDTLYVHTHRQFYRNCRVSGTIDFVFGDAKAVFQNCEFVIRRPMEHQQCIVTAQGRKDRRETTGIVIHNSRITGDASYLPVKAKNRAFLGRPWKEFSRTIIMNTEIDDVIDPEGWLKWNETFALNTLFYTEYRNRGRGSGQGRRVRWRGIKRISDRAAREFAPGNFLRGNTWIPQTRIPYNA 700          

Query:  160 IQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVI-KNSTTLKELAK-DSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNI-------KTGRRLLQDAATATDEN 693
            +  IC  TDYK+ C  +L+ V S   DP+ L+++ F +AI  +R  I +    LK  A  D    +AL  C+EL++ AIDDL  + DK   F FT+L  +VEDL VWLS ++TY+QTC+DGF+    +A   M + ++  Q LTSNGLA+ + +  L KA  I       + GR  +  + ++ DE+
Sbjct:   48 VSIICASTDYKQDCTTSLATVRS--PDPRNLIRSAFDLAIISIRSGIDRGMIDLKSRADADMHTREALNTCRELMDDAIDDLRKTRDKFRGFLFTRLSDFVEDLCVWLSGSITYQQTCIDGFEGIDSEAAVMMERVMRKGQHLTSNGLAIAANLDKLLKAFRIPFPFLRSRRGRLGILGSGSSRDES 232          

Query:  121 KSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVAS-NVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSF-DKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQ-FLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPA---WIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELN-KAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMK-KLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            ++ GE  S S KA+   C  T +K+ C + L    + + + P+EL K   +V I +L +V+   +  + +  D+  + A+  C EL+  A+D L ++    L  FD         DL+ WLS+  TY++TC+D        +     +  LK S E+TSN LA+++ +  +   +  +  RRLL+             AK++ A    ++ RRL    +  L  K  +VV+K G GKY+TI EAL ++ + NE K  +IYVK+GVY E+V  +K   NV+++GDG +KT+++   N+ DG            G  F+A+D+GF NTAG   HQAVAL V +DLS+FY C MD +QDT+Y    RQFYRDC I GT+DFIFG+AA VFQ C+++ R+P++ Q   +TA GR D    + + + NCTI   +  D   + + +LGRPW   +  ++M+S +D  I P+GW+ WTG    +T ++ E+ N G GA    RV W G+K  LT ++A  FT   FI G+ W+  + VP+
Sbjct:   58 ENNGEPISVSVKAL---CDVTLHKEKCFETLGSAPNASRSSPEELFKYAVKVTITELSKVLDGFSNGEHM--DNATSAAMGACVELIGLAVDQLNETMTSSLKNFD---------DLRTWLSSVGTYQETCMDALVEANKPSLTTFGENHLKNSTEMTSNALAIITWLGKIADTVKFRR-RRLLETG----------NAKVVVADLPMMEGRRL--LESGDLKKKATIVVAKDGSGKYRTIGEALAEVEEKNE-KPTIIYVKKGVYLENVRVEKTKWNVVMVGDGQSKTIVSAGLNFIDGTPTFETATFAVFGKGFMARDMGFINTAGPAKHQAVALMVSADLSVFYKCTMDAFQDTMYAHAQRQFYRDCVILGTVDFIFGNAAVVFQKCEILPRRPMKGQQNTITAQGRKDPNQNTGISIHNCTI---KPLDNLTDIQTFLGRPWKDFSTTVIMKSFMDKFINPKGWLPWTGDTAPDTIFYAEYLNSGPGASTKNRVKWQGLKTSLTKKEANKFTVKPFIDGNNWLPATKVPF 560          

Query:  136 QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDN-RRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            Q ST++K+I++ICQPTDY++TCE++LSK A N TDP +LV+AGF+V I  L+  I  STTLKELAKD  A+QAL NC+EL++ AI +L  SFD +  F  ++ D YV +LKVWLSA +TY++TCLDGF+NTTG AG KM++ L  S +LTSNGLAMV  V+++ K LNI   T RRLL+    A DE         P+W++  +R+ L   TP T+K D +V++ G G+YKTI EA++ IPK    + FVIY+KEGVY E V   +  T+V++IGDGPTKT ITG  NYA+G            GD+F+AKD+GFEN+AGAIGHQAVALRVQ+D+S+FYNC +DGYQDTLY  T RQFYRDCTI+GTIDFIFGDA AVFQNCK++VRKPL+NQ C+VTA GR + R P+  ++QNCTI+ +  Y   +  NKAYLGRPW  L+R IVMQS IDD+IAPEGW+ W G+   NT ++ E+ N+G GA  + RV W+G+KKLTPE A  +TA KFI GD WI  +GVPY AGM++
Sbjct:   52 QISTTSKSIKAICQPTDYRETCEESLSKAAGNTTDPSKLVQAGFKVTIEALQNAINRSTTLKELAKDPMASQALDNCRELMDDAIAELEHSFDLIESFQASQFDEYVNNLKVWLSATITYQRTCLDGFENTTGSAGEKMKELLMASSQLTSNGLAMVDGVTSILKDLNIPGLTSRRLLE----ADDE--------FPSWVNGGKRMLLLKETPATIKADAIVAQDGSGQYKTIAEAIEKIPKKKN-ETFVIYIKEGVYKEQVSLARSHTHVLMIGDGPTKTKITGNLNYANGVQTFKTATVSISGDHFMAKDIGFENSAGAIGHQAVALRVQADMSVFYNCQIDGYQDTLYAHTKRQFYRDCTITGTIDFIFGDAIAVFQNCKLVVRKPLDNQQCIVTAQGRNETREPTGFVIQNCTITADPQYFPVRLQNKAYLGRPWRELSRTIVMQSHIDDLIAPEGWLPWLGSFGLNTLFYSEYNNKGQGAVETNRVKWAGIKKLTPEAADGYTAAKFIQGDEWIPQTGVPYTAGMIS 570          

Query:  136 QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            Q S S KA+++ICQPTDY+KTCE+NL K A N TDP+EL+K  F++A   + E  K S  L+EL+KD R   ALQ+C+EL+  ++D+L  S +K+  FD T+++  + D+K WLSA++TY++TCLDGFQNTT +AG +M++ LK S EL++N LA+VS +S+   +L     RRLLQD             +I P W D  +  L  A    +K D+VV+K G G + TI +AL  +P  +  K FV+Y+K G+Y E++ F+K MTN+M+IGDG   T I G KN+ DG            GD F+AK++GFEN AGAI HQAVALRV +D ++FYNC+MDG+QDT+YT   RQFYRDC+ISGTIDF+FGDA+AVFQNCK ++RKPLENQ C+VTA GR   R PSA+I+QN TI+       +++L K+YLGRPW   +R I+M+S IDDVI PEGW+ W GT    TCW+ EF N G G+  + RV W+G+K +  + A DFT G+F  G  WI  +G+PY
Sbjct:   54 QVSASMKAVKAICQPTDYRKTCEENLQKAAGNTTDPRELIKMAFKIAEKHVNEASKKSKVLEELSKDPRTRGALQSCRELMTMSVDELKQSLNKVTDFDITEIEKLMADVKTWLSASITYQETCLDGFQNTTTNAGKEMKKGLKLSMELSANLLAIVSGISSAIPSLESLGQRRLLQDDLPVLGHGD----QIFPTWTDFGKRRLLAAPASKIKADIVVAKDGSGDFSTIRDALHHVPIKSS-KTFVLYIKAGIYQEYIDFNKSMTNLMVIGDGRETTRIVGNKNFVDGINTYHTATVVVLGDNFVAKNIGFENNAGAIKHQAVALRVSADYALFYNCSMDGHQDTMYTHAKRQFYRDCSISGTIDFVFGDASAVFQNCKFLIRKPLENQQCIVTAQGRKMRRQPSAIIIQNSTITAHPDLFPERKLFKSYLGRPWKEFSRTIIMESFIDDVIQPEGWLPWLGTFGLKTCWYTEFNNNGPGSSKAARVKWNGIKTIDRQHALDFTPGRFFKGGAWIKTTGIPY 571          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            HK  S   Q S S KA+++ICQPTDY+KTCE++L K A N TDPKEL+K  F++A  Q+ E  + S  L+EL+KD R   ALQ+CKEL+  ++ +L  S DK+  FD ++L+  + D+K WLSA++TY++TCLDGF+NTT DAG KM++ +K   EL++N L +VS +S+   +L   T RRLLQD     D          P W D     L  A    +K D+VV+K G G + TI EALK +P  ++ K FV+++K GVY E++   K M N+++IGDG   T I G KN+ DG            GD F+AK++GFEN AGAI HQAVALRV +D +IFYNC+MDG+QDTLYT   RQFYRDC+ISGTIDF+FGDA+AVFQNCK +VRKPLENQ C+VTA GR   R PSALI+Q+ TI+       +++  K+YLGRPW   +R I+M+S IDD+I PEGW+ W GT    TCW+ EF N G G+  + RV W+G+K +  + A DFT G+F+ GD WI  +G+PY
Sbjct:   49 HKSTS---QVSASVKAVKAICQPTDYRKTCEESLQKAAGNTTDPKELIKIAFKIAEKQINEASEKSKLLEELSKDPRTRGALQSCKELMNMSVGELKQSLDKVTDFDLSELEKMMADVKTWLSASITYQETCLDGFENTTTDAGKKMKKGMKLGMELSANLLDIVSGISSAIPSLESFTHRRLLQD-----DLPVLGHGDQFPTWTDFGTRRLLAAPVSKIKADIVVAKDGSGDFSTIREALKHVPIKSK-KAFVLHIKAGVYQEYLEISKGMINLVVIGDGKENTRIIGNKNFVDGINTFHTATVAVLGDNFVAKNIGFENNAGAIKHQAVALRVSADYAIFYNCSMDGHQDTLYTHAKRQFYRDCSISGTIDFVFGDASAVFQNCKFLVRKPLENQQCIVTAQGRKMRRQPSALIIQSSTITAHPDLFPERKQFKSYLGRPWKEYSRTIIMESFIDDLIQPEGWLPWLGTFGLKTCWYTEFNNYGPGSSKNLRVKWNGIKTINRQHAMDFTPGRFLKGDSWIKATGIPY 570          

Query:  142 STSTKAIQSICQPTDYKKTCEDNLSKVAS---NVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTG--RRLLQDAATATDENRFQRAKIIPAWIDNR-RLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            S  ++ I+++C  T Y++TC+  L K      ++  PK L+K   + A  ++++V+K +++ K    D R   A ++C EL+E A ++L DS   +G  D  KL     DL  WLSA M+Y+QTC+DGF    G   + M +  K S+ELTSN LAMVS +++  K+        RRLL     +   N+      +P W+ N  R  L  A+    KP+V V+K G G +KTI+EAL  +P   E + +VI+VK+G+YDE V   K M+N+ + GDG  KT++TG KN+ADG            GD F+ K +GF NTAG   HQAVA+RVQ+D +IF NC  +GYQDTLY QTHRQFYR C I+GT+DFIFGDA A+FQNC + VRKPLENQ  ++TA GR+D    + ++LQNC I  ++     K   ++YLGRPW   +R I+M+S I D I P+GW+ W G     T ++ E+ N+G GA+ + R+ W G   +  E+A  FTA  F  GD WI  +G P   G+
Sbjct:   73 SRVSRVIKTVCNATTYQETCQKTLEKEVEKDPSLAQPKNLLKIAIKAADEEIKKVLKKASSFK--FDDPREKAAFEDCLELVENAKEELKDSVAHVGD-DLGKLAKNAPDLNNWLSAVMSYQQTCIDGFPE--GKLKSDMEKTFKASKELTSNSLAMVSSLTSFMKSFPFPAALNRRLLAKEDNSPALNKDD----LPGWMSNEDRRILKGASKDKPKPNVTVAKDGSGDFKTISEALAAMPAKYEGR-YVIFVKQGIYDETVTVTKKMSNITIYGDGSQKTIVTGNKNFADGVQTFRTATFAVLGDGFLCKAMGFRNTAGPEKHQAVAIRVQADRAIFLNCRFEGYQDTLYAQTHRQFYRSCVITGTVDFIFGDATAIFQNCLITVRKPLENQQNLITAQGRVDGHETTGIVLQNCRIEPDKDLVPVKTKIRSYLGRPWKEFSRTIIMESTIGDFIHPDGWLPWQGEFGLKTLYYAEYNNKGAGAKTTARIKWPGYHIINNEEAMKFTAEPFYQGD-WISATGSPIHLGL 592          

Query:  139 TSTSTKAIQSICQPTDYKKTCEDNLSKVAS---NVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWI--DNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            TS   + I+++C  T Y+ TC++ L K      +   PK+L+K   + A  ++ +V+K +++ K      R   A  +C EL+E A ++L    D++G  D  KL     DL  WLSA M+Y+QTC+DGF    G   + M +  K ++ELTSN LAMVS +++  K  +      RRLL +   +   ++      +P W   ++RR+ L  A     KP V V+K G G +KTI+EAL  +P   E + +VI+VK+G+YDE V   K M N+ + GDG  KT++TG KN+ADG            G+ F+ K +GF NTAG   HQAVA+RVQ+D +IF NC  +GYQDTLY QTHRQFYR C I+GT+DFIFGDAAA+FQNC + VRKPLENQ  +VTA GR+D    + ++LQNC I  ++G    K   ++YLGRPW   +R ++M S I D I P+GW+ W G     T ++ E+ N+G+GA+ + R+ W G   +  E+A  FT   F   D WI  +G P   G+
Sbjct:   75 TSHVARVIKTVCNATTYQDTCQNTLEKGMRKDPSSVQPKDLLKIAIKAADKEIEKVLKKASSFK--FDKPREKAAFDDCLELIEDAKEELKHCIDRVGN-DIGKLTKNAPDLNNWLSAVMSYQQTCIDGFPE--GKLKSDMEKTFKAARELTSNSLAMVSSLASFLKNFSFSGTLNRRLLAEEYNSPSLDKDG----LPGWTSHEDRRI-LKGANQDKPKPHVTVAKDGSGDFKTISEALAAMPAKYEGR-YVIFVKQGIYDETVTVTKKMVNITMYGDGSQKTIVTGNKNFADGVQTFRTATFAVLGEGFLCKAMGFRNTAGPEKHQAVAIRVQADRAIFLNCRFEGYQDTLYAQTHRQFYRSCVITGTVDFIFGDAAAIFQNCLITVRKPLENQQNIVTAQGRIDGHETTGIVLQNCRIEPDKGLVPVKTKIRSYLGRPWKEFSRTVIMDSTIGDFIHPDGWLPWQGDFGLKTLYYAEYNNKGIGAQTNARIKWRGYHIIKKEEAMKFTVETFYQVD-WISATGSPVRLGL 595          

Query:  112 HKGKSGG---EQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLK-ELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-----TGRRLLQDAATATDENRFQRAKIIPAWID--NRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYA-DGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNK--AYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            +KG  GG   E  S   K    +CQP++YK+ C + LS V  N TDPKE VK     A   +++    S  L  + +KD R   AL +CKELL+YA+ +L  S   +G  D    +  V +L+ WLS+ + Y++TC+DGF + +       + F+  S  LT N LA++S +S   K++ ++       RRLL +                P W    +R+L LA      +KP+ VV++ G G++KTI+ A+   P N + + ++IYVK G+Y E+V  DK   NV + GDGP KT++TG K++A DG             D FIAK +GF+NTAG  GHQAVALRV SD+S F NC MDGYQDTL  Q  RQFYR+C ISGT+DFIFG  AAV QN  ++VR+P +NQ   VTA GR +  + + L++ NC I  E+    E  K   YLGRPW   +R +VM+S++ D I P GWM W G+ + +T ++ E+ NRG GA  +KRV W     +   +A  FTAG+F+ G  WI  +GVP + G+
Sbjct:   29 NKGSDGGKKEENLSPEMKIATQLCQPSEYKEACTETLSSV--NSTDPKEFVKQAILAASDAVKKSFNFSEDLVVKASKDKREKMALDDCKELLDYAVQELQASMSLVGDSDLHTTNERVAELQSWLSSVLAYQETCVDGFSDNSTIKPTIEQGFVDASH-LTDNVLAIISGLSGFLKSVGLQFNIPSNSRRLLAEDG-------------FPTWFSGADRKL-LAAQGNGKVKPNAVVAQDGSGQFKTISAAIAAYPNNLKGR-YIIYVKAGIYREYVTVDKKKPNVFIYGDGPRKTIVTGSKSFAKDGLGTWKTATFVAEADGFIAKSMGFQNTAGPDGHQAVALRVSSDMSAFLNCRMDGYQDTLLYQAKRQFYRNCVISGTVDFIFGYGAAVIQNSLIVVRRPNDNQQNSVTADGRKEKHATTGLVIHNCRIVPEQKLVAERFKIPTYLGRPWKPFSRTVVMESELADFIQPAGWMPWAGSIHLDTLYYAEYANRGAGANTNKRVNWKTFHVINRNEALQFTAGQFLKGASWIKNAGVPVLLGL 557          

Query:  118 GKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTL-KELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-----TGRRLLQDAATATDENRFQRAKIIPAWID--NRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYA-DGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            G++     S S K    +CQP+DYK+ C   LS V  N TDPKE VK     A   + +    S  L  + +KD R   AL +CKELL+YA+ +L  S   +G  D    ++ V +L+ WLSA + Y++TC+DGF + +       + F+  SQ LT N LA++S +S   K++ ++       RRLL +                P W    +R+L LA      +KP+ VV++ G G++KTI+ A+   P   + + ++IYVK G Y E+V  DK   NV + GDGP KT++TG K++A DG             D FIAK +GF+NTAG  GHQAVALRV SD+S F NC MDGYQDTL  Q  RQFYR+C ISGT+DFIFG  AAV QN  ++VR+P  NQ   VTA GR +  + + L++ NC I  E+    D+     YLGRPW   +R +VM+S++ D I P GWM W G+ + +T ++ E+ NRG GA  +KRV W     +   +A  FTAG+F+ G  WI  +GVP + G+
Sbjct:   35 GENEAGNISASMKIANQLCQPSDYKEACTKTLSSV--NSTDPKEFVKHAILAASDAVTKSFNFSEELIVKASKDKREKMALDDCKELLDYAVQELQASMSMVGDSDLHTTNNRVAELQSWLSAVLAYQETCVDGFDDKSTIKPIIQQGFVNASQ-LTDNVLAIISGLSDFLKSMGLQFNIPSNSRRLLGEDG-------------FPTWFSGADRKL-LAAQDKGKVKPNAVVAQDGSGQFKTISAAIAAYPNKLKGR-YIIYVKAGTYREYVTIDKKKPNVFIYGDGPRKTIVTGSKSFAKDGLGTWKTATFVAEADGFIAKSIGFQNTAGPDGHQAVALRVSSDMSAFLNCRMDGYQDTLLYQAKRQFYRNCVISGTVDFIFGYGAAVIQNSLIVVRRPNANQQNSVTADGRKENHATTGLVIHNCRIVPEQKLVADRFKIPTYLGRPWKPFSRTVVMESELADFIQPAGWMPWAGSLHLDTLYYAEYANRGAGANTNKRVNWKTFHVINRNEALRFTAGQFLQGAAWIKNAGVPVLLGL 558          

Query:  121 KSGG-----EQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREV--IKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-----TGRRLLQDAATATDENRFQRAKIIPAWID--NRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYA-DGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERG-YDKELN-KAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            +SGG     E  S   KA+ ++CQPT YK+ C + LS V  N TDPKEL+K G       L++   + +   +K  + + RA  AL +CKELL+ A + L D+  K+G  D   L  + +D + WLS+ + Y++ CLDGF+  +    A+++       +LT N L +++ +S +  +L +K     T RRLLQ             A   P+W+   +R+L LA+      +P+ VV+  G GK+KTIN AL   PK  + + +VIYVK G+Y E+V   K   NV + GDG  +T++TG KN+A DG             + FIAK++GF NTAG  GHQAVA+RV SD+S FYNC +DGYQDTL  Q  RQFYR+C +SGT+DF+FG  + V QN  ++VR+P  +Q   VTA GR +   P  +++ NC I  E+       N K YLGRPW + +R +VM++Q+ D I P+GW  W+G    +T ++ E+ N G GA   +RV W  +  L   +A  FTAG F+ G +WI  +GVP + G+
Sbjct:   28 RSGGSVEHTESLSPQMKAVSTLCQPTYYKEACTNTLSAV--NSTDPKELIKGGILAISDSLKKSSNLTDDLVVKNNSDEPRAKMALNDCKELLQDASEQLQDTLSKVGGIDLQSLSDHADDYRTWLSSIIAYQEMCLDGFEENS-PLKAQVQNSTDYGSQLTDNVLNILAGLSQVLGSLGLKFNAPSTSRRLLQ-------------ADGYPSWMSAADRKL-LASRGNGGARPNAVVAHDGSGKFKTINAALAAYPKGLKGR-YVIYVKAGIYREYVTVTKDKPNVFIYGDGARRTIVTGNKNFAKDGIGTWKTATFIVEANGFIAKNMGFSNTAGPDGHQAVAIRVNSDMSAFYNCRLDGYQDTLCYQAGRQFYRNCVLSGTVDFLFGYGSVVIQNSMIVVRRPNPSQFNTVTADGRKERGQPGGIVIHNCRIVPEQKLVPVRFNIKTYLGRPWKAFSRTVVMETQLADFIQPDGWAPWSGNQFLDTLYYAEYANTGPGAATKRRVRWKTLHFLRRNEALQFTAGAFLRGGQWIRNTGVPALLGL 556          

Query:  109 RHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKD-SRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTS----QELTSNGLAMVSEVSTLFKALNIK-----TGRRLLQDAATATDENRFQRAKIIPAWID--NRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYA-DGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            R  G +  E  S   KA+ ++CQPT YK+ C + LS  A N TDPKEL+K G       L+     +  L     + SR   AL +CKELL+ A + L D+  K+G  D   L +  +D + WLS+ + Y++ CLDGF+N     G+ +R  ++ S     ELT N L +++ +S +  +L +K     T R+LLQ             A   P W+   +R+L LA+     ++P+ VV++ G G++KTI+ AL   PKN + + +VIYVK G Y E+V   K   NV + GDG  KT++TG K++A DG             + FIAK +GF NTAG  GHQAVA+R  SD+S FYNC  DGYQDT+  Q  RQFYR+C +SGT+DF+FG  +AV QN  +IVR+P  NQ   VTA GR +   P  +++ NC I  E+    D+   K YLGRPW + +R +VM+S++ D I P+GW  W+G    +T ++ E+ N G GA  ++RV W  +  L   +A  FT G F+ G +WI  +G+P + G+
Sbjct:   28 RSNGSNDTESLSPQMKAVSALCQPTYYKEACTNTLS--ALNSTDPKELIKGGILAISASLKNSFNVTDDLVAKTDNASRDKMALNDCKELLQNASESLEDTLSKVGEIDLLSLSNRTDDFRTWLSSIIGYQEMCLDGFEN-----GSSLRDQVQKSTDYGSELTDNVLNILAGLSQVLNSLGLKLNIPSTSRQLLQ-------------ADGFPTWMSASDRKL-LASRGNGGVRPNAVVAQDGSGQFKTISAALAAYPKNLKGR-YVIYVKAGTYREYVAVAKDQPNVFIYGDGSRKTIVTGNKSFAKDGLGTWKTATFIVEANGFIAKSIGFTNTAGPDGHQAVAIRANSDMSAFYNCRFDGYQDTVLYQAGRQFYRNCVLSGTVDFLFGYGSAVIQNSLIIVRRPNPNQFNTVTADGRKERGQPGGVVIHNCRIVPEQKLVPDRLKIKTYLGRPWKAYSRTVVMESKLADFIQPDGWAPWSGNEFLDTLYYAEYANAGPGAATNRRVRWKTLHFLKRSEALQFTVGTFLQGGQWIKNNGIPVLMGL 554          

Query:  109 RHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKD-SRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTS----QELTSNGLAMVSEVSTLFKALNIK-----TGRRLLQDAATATDENRFQRAKIIPAWID--NRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYA-DGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            R  G +  E  S   KA+ ++CQPT YK+ C + LS  A N TDPKEL+K G       L+     +  L     + SR   AL +CKELL+ A + L D+  K+G  D   L +  +D + WLS+ + Y++ CLDGF+N     G+ +R  ++ S     ELT N L +++ +S +  +L +K     T R+LLQ             A   P W+   +R+L LA+     ++P+ VV++ G G++KTI+ AL   PKN + + +VIYVK G Y E+V   K   NV + GDG  KT++TG K++A DG             + FIAK +GF NTAG  GHQAVA+R  SD+S FYNC  DGYQDT+  Q  RQFYR+C +SGT+DF+FG  +AV QN  +IVR+P  NQ   VTA GR +   P  +++ NC I  E+    D+   K YLGRPW + +R +VM+S++ D I P+GW  W+G    +T ++ E+ N G GA  ++RV W  +  L   +A  FT G F+ G +WI  +G+P + G+
Sbjct:   28 RSNGSNDTESLSPQMKAVSALCQPTYYKEACTNTLS--ALNSTDPKELIKGGILAISASLKNSFNVTDDLVAKTDNASRDKMALNDCKELLQNASESLEDTLSKVGEIDLLSLSNRTDDFRTWLSSIIGYQEMCLDGFEN-----GSSLRDQVQKSTDYGSELTDNVLNILAGLSQVLNSLGLKLNIPSTSRQLLQ-------------ADGFPTWMSASDRKL-LASRGNGGVRPNAVVAQDGSGQFKTISAALAAYPKNLKGR-YVIYVKAGTYREYVAVAKDQPNVFIYGDGSRKTIVTGNKSFAKDGLGTWKTATFIVEANGFIAKSIGFTNTAGPDGHQAVAIRANSDMSAFYNCRFDGYQDTVLYQAGRQFYRNCVLSGTVDFLFGYGSAVIQNSLIIVRRPNPNQFNTVTADGRKERGQPGGVVIHNCRIVPEQKLVPDRLKIKTYLGRPWKAYSRTVVMESKLADFIQPDGWAPWSGNEFLDTLYYAEYANAGPGAATNRRVRWKTLHFLKRSEALQFTVGTFLQGGQWIKNNGIPVLMGL 554          

Query:    1 MSGGEVQNKKKIAIIGXXXXXXXXXXXXXXXXXXXXRHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTGV 1722
            M G +  NKKK+AIIG                    R    S    TSTSTKA+Q+ICQPTDYKKTCE++L+  A NVTDPKEL+K GFQVA+ +LR VI+ S TLKELAKD     ALQNCKELLEYAIDDL DS ++LG FD +KLD YVEDLKVWLSAAMTYEQTCLDGF+NTTGDAG KMRQFLKTSQELT+N LAM   VST+F ALN+K+GRRLL+ AA  T   +FQ+AK+IPAWID+RRL+LATATP TLKPDVVV+K G GKYKT+NEALKDIPKNN VKVFVIYVKEGVY+E V FDKHMTNVMLIGDGPTKTVITGRKN+A+G            GDYFIAKD+GFENTAGAIGHQAVALRVQSDLSIFYNC MDGYQDTLYTQT+RQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLD RSPS + +QNCTISGE GY+K+LNKAYLGRPW   AR IV+QSQIDDVIAPEGWM+W G+ NH +CWFGEFGNRG+GA+ ++R TW G+KKL  + AADFTAG+F+FGDRWI PSGVPYVAGMM GV
Sbjct:    1 MGGADGSNKKKVAIIGASALILVAMVVAVTVGVTVSRRDRGSSDGHTSTSTKAVQAICQPTDYKKTCEESLAGAAGNVTDPKELIKVGFQVAMDKLRGVIEKSVTLKELAKDPSTGDALQNCKELLEYAIDDLSDSSERLGAFDMSKLDLYVEDLKVWLSAAMTYEQTCLDGFENTTGDAGEKMRQFLKTSQELTNNALAMADGVSTMFGALNVKSGRRLLE-AAAGTAVKKFQKAKVIPAWIDSRRLELATATPQTLKPDVVVAKNGGGKYKTVNEALKDIPKNNAVKVFVIYVKEGVYEEQVIFDKHMTNVMLIGDGPTKTVITGRKNFAEGTMTMQTATVGVVGDYFIAKDIGFENTAGAIGHQAVALRVQSDLSIFYNCKMDGYQDTLYTQTYRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDRRSPSGITIQNCTISGELGYEKDLNKAYLGRPWKKYARTIVIQSQIDDVIAPEGWMDWIGSXNHQSCWFGEFGNRGLGADQTRRATWRGIKKLXAQHAADFTAGRFVFGDRWIQPSGVPYVAGMMPGV 573          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            KKK+AIIG                    R  G S    TSTSTKAIQ+ICQPTDYKKTCE++LS  A NVTDPKEL+K GFQV +  LR VI+ STTLK+LAKD     ALQNCKELLEYAIDDLGDSFD++G FD +KLD YVEDLKVWLSAAMTYEQTCLDGF+NTTGDAG KMR+FLKTSQELT+NGLAMV +VST+F ALN+K+GRRLL+ A   T   +FQ+AK+IPAWIDNRRLDLATATP TLKPDVVV+KKG GKY T+NEALKDIPK+N VKVFVIYVKEGVY+EHV FDKHMTNVMLIGDGPTKT+ITGRKN+A+G            GDYFIAKD+GFENTAGA+GHQAVALRVQSDLSIFYNC MDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACM                              +LNKAYLGRPW + AR IVMQSQIDDVIAPEGWMEW G+ NH +CW GEFGNRG+GA+ SKR TW G+KKLT + AADFTAG+F+FGDRWI PSGVPYVAGMM
Sbjct:   10 KKKLAIIGASALILVAMVVAVTVGVTVSRRGGGSSDGHTSTSTKAIQAICQPTDYKKTCEESLSGAAGNVTDPKELIKVGFQVTMDMLRGVIEKSTTLKDLAKDPSTGDALQNCKELLEYAIDDLGDSFDRIGAFDMSKLDLYVEDLKVWLSAAMTYEQTCLDGFENTTGDAGEKMREFLKTSQELTNNGLAMVDQVSTMFGALNVKSGRRLLE-ATAGTGAKKFQKAKVIPAWIDNRRLDLATATPQTLKPDVVVAKKGGGKYTTVNEALKDIPKDNAVKVFVIYVKEGVYEEHVLFDKHMTNVMLIGDGPTKTIITGRKNFAEGTKTMQTATVGVVGDYFIAKDIGFENTAGAVGHQAVALRVQSDLSIFYNCKMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACM------------------------------DLNKAYLGRPWKNYARTIVMQSQIDDVIAPEGWMEWIGSNNHQSCWLGEFGNRGLGADQSKRATWRGIKKLTAQHAADFTAGRFVFGDRWIQPSGVPYVAGMM 541          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRR-LDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            HK   GG  T TSTKAI++ICQPTDYK+TCE +L   A N T+PK+L+KAGF V + +LR +IKNSTTL+ELAKD   NQAL+NCKELLEYAIDDL  SF KLGPFD +K+D Y EDLKVWLSAA+TY+QTCLDGFQNT GDAG KM++FL T+Q+LTSNGLAMV+E++++  +LN+K  RR L  A      N     K+IP WI+N+R LD++T TP ++KPD VV+K G G+Y+TI EA+K IPKNN  K FVIYVKEGVY E+V  DK+MTNVMLIGDG  KT +TG KN+A G            GDYFIAKD+G EN+AGA GHQAVALRVQSDLSIFY C MDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAA VFQNCKMIVRKP++NQACMVTA GR+D R PS +ILQNCTISG+  Y   K+ NK+YLGRPW +LAR +VMQSQID +IAPEGWMEWTG+ NH +CWFGE+ NRG G+ +SKRV WSG+K L+ +QA  FT+GKF+ GD+WI PSGVPYVAGM++
Sbjct:   42 HKNSDGGHVT-TSTKAIKAICQPTDYKETCERSLESAAGNSTEPKDLIKAGFNVTMDKLRAIIKNSTTLQELAKDESTNQALENCKELLEYAIDDLTTSFQKLGPFDISKIDDYAEDLKVWLSAAITYQQTCLDGFQNTKGDAGDKMKRFLNTTQQLTSNGLAMVTEITSVLGSLNLKANRRRLL-AGGGGGGNAKNAPKVIPTWINNKRSLDVSTVTPQSIKPDAVVAKDGSGQYETIGEAVKMIPKNNADKTFVIYVKEGVYSEYVMIDKYMTNVMLIGDGAXKTKVTGSKNFAAGVQTFQTATVVVVGDYFIAKDIGIENSAGAEGHQAVALRVQSDLSIFYRCQMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAVVFQNCKMIVRKPMDNQACMVTAQGRIDRRQPSGIILQNCTISGDPEYIPVKDKNKSYLGRPWKNLARTVVMQSQIDGIIAPEGWMEWTGSNNHQSCWFGEYRNRGPGSHMSKRVKWSGIKNLSADQAVAFTSGKFVEGDKWIKPSGVPYVAGMVS 577          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIP-KNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            KKKIAII                     + KG     +     KAI++ICQ T YK+TC+ +L K   + TDPK+L+KA FQVA  ++ EVIKNS TLKE AKD  A+QAL  CKELLE A++DL  + DK+GPFD +K+  Y+ DLKVWLSAA+ ++ TCLD F++T G+AG KMR FLKT+QELTSNGLAMVSE+S L  +  + + RRL+  +     +  +   K +P W+ +R LDL TATP +LKP+VVV+K G GKYKTINEALK++P K+NE   FVIY+K+G+Y+E V  DK MTNV++IGDGPT T I+G K++ADG            G+YF+AK +GFENTAG + HQAVALRVQSD SIF+NC+MD YQDTLYTQT+RQFYRDCTI+GT+DFIFGD  A+FQNCKM+VRKP E QACMVTA GR D    + + LQNCTI+GE  Y   K+ NKAYLGRPW   AR +VMQS ID+ IAPEGW EWTG   H  C+FGE+GNRG   ++++RV WS +K+LTP+QAA FT  +   GD+W+ PSGVPYV GMM
Sbjct:   64 KKKIAIIAVLVVLLVAMIVAVTVGVKMAK-KGNKKPAKVGAKKKAIETICQATTYKETCQSSLEKETGDTTDPKDLIKAEFQVAADKVNEVIKNSNTLKEYAKDPMASQALGVCKELLETAVEDLLGAVDKMGPFDVSKISDYLADLKVWLSAAVNHQATCLDAFEDTKGEAGEKMRGFLKTAQELTSNGLAMVSEISRLVDSPKLNSHRRLMSSSKGGQTKRNY---KPVPGWMSDRHLDLLTATPESLKPNVVVAKDGTGKYKTINEALKEVPQKSNEA--FVIYIKKGMYEETVIVDKEMTNVVMIGDGPTMTRISGSKSHADGITTMNTATFAAVGNYFVAKGIGFENTAGHVKHQAVALRVQSDFSIFFNCHMDAYQDTLYTQTYRQFYRDCTITGTVDFIFGDGVALFQNCKMVVRKPGEAQACMVTAQGRTDRNEITGIFLQNCTITGEPDYMAVKDKNKAYLGRPWKKFARVVVMQSSIDEAIAPEGWTEWTGEKYHQNCFFGEYGNRGPRKDMTQRVKWSTVKRLTPDQAAAFTPARVFEGDKWVKPSGVPYVPGMM 623          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRHKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIP-KNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            KKKIAII                     + KG     +     KAI++ICQ T YK+TC+ +L K   + TDPK+L+KA FQVA  ++ EVIKNS TLKE AKD  A+QAL  CKELLE A++DL  + DK+GPFD +K+  Y+ DLKVWLSAA+ ++ TCLD F++T G+AG KMR FLKT+QELTSNGLAMVSE+S L  +  + + RRL+  +     +  +   K +P W+ +R LDL TATP +LKP+VVV+K G GKYKTINEALK++P K+NE   FVIY+K+G+Y+E V  DK MTNV++IGDGPT T I+G K++ADG            G+YF+AK +GFENTAG + HQAVALRVQSD SIF+NC+MD YQDTLYTQT+RQFYRDCTI+GT+DFIFGD  A+FQNCKM+VRKP E QACMVTA GR D    + + LQNCTI+GE  Y   K+ NKAYLGRPW   AR +VMQS ID+ IAPEGW EWTG   H  C+FGE+GNRG   ++++RV WS +K+LTP+QAA FT  +   GD+W+ PSGVPYV GMM
Sbjct:    8 KKKIAIIAVLVVLLVAMIVAVTVGVKMAK-KGNKKPAKVGAKKKAIETICQATTYKETCQSSLEKETGDTTDPKDLIKAEFQVAADKVNEVIKNSNTLKEYAKDPMASQALGVCKELLETAVEDLLGAVDKMGPFDVSKISDYLADLKVWLSAAVNHQATCLDAFEDTKGEAGEKMRGFLKTAQELTSNGLAMVSEISRLVDSPKLNSHRRLMSSSKGGQTKRNY---KPVPGWMSDRHLDLLTATPESLKPNVVVAKDGTGKYKTINEALKEVPQKSNEA--FVIYIKKGMYEETVIVDKEMTNVVMIGDGPTMTRISGSKSHADGITTMNTATFAAVGNYFVAKGIGFENTAGHVKHQAVALRVQSDFSIFFNCHMDAYQDTLYTQTYRQFYRDCTITGTVDFIFGDGVALFQNCKMVVRKPGEAQACMVTAQGRTDRNEITGIFLQNCTITGEPDYMAVKDKNKAYLGRPWKKFARVVVMQSSIDEAIAPEGWTEWTGEKYHQNCFFGEYGNRGPRKDMTQRVKWSTVKRLTPDQAAAFTPARVFEGDKWVKPSGVPYVPGMM 567          

Query:  121 KSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVT-DPKELVKAGFQVAIGQLREVIKNSTTLKELAK--DSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWID--NRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNK--AYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            KS  +Q STS+KA+ +IC PTDYK+ C D+L  VA N +  PK+L++A     I  ++  I+NS ++ +  K  +S    A+ +CK+LLE AI DL  SF  +G  +   +    E+L+ W SA ++++Q+CLDG      +    M+  L  + +LTSN LA+ + ++ + +  NI   + L   +++   E         P+W    +RRL LA      +KP+ VV+K G G++KTI  AL   PK  + + ++IYVK GVY+E+V   K+  NV + GDGP KT++TG K++ADG            G+ F+AK +GF+NTAGA  HQAVALRVQS++S F+NC MD YQDTLY QTHRQFYR+C ISGT+DFIFGD+  + QN  +IVRKP++NQ   VTA GR D R  +A+++QNC I  E        K  +YLGRPW + AR ++M+S++ D I P GW+ W+G    +T ++ E+GNRG GA  ++RV W G   +    A  FTAG F+  DRW+  +G+PY AG+ T
Sbjct:   32 KSNKDQLSTSSKAVAAICDPTDYKEACIDSLGSVAKNDSATPKDLIQAAIDSTIKTVKSAIENSNSIAKSFKAINSTGKMAMDDCKDLLESAIADLQASFSFVGDSNMHTMHDREEELRNWFSAVISFQQSCLDGIPQE--ELQKLMKDSLLNATQLTSNALAIATSIAQILENFNITLNKDLRPTSSSRILEQENDGHGQYPSWFPAADRRL-LAKQDNGGVKPNAVVAKDGSGQFKTIGAALAAYPKGLQGR-YIIYVKAGVYNEYVTVTKNQVNVFMYGDGPRKTMVTGSKSFADGITTQNTATFAAIGNGFLAKGMGFQNTAGAQKHQAVALRVQSEMSAFFNCRMDAYQDTLYAQTHRQFYRNCVISGTVDFIFGDSPTLIQNSLIIVRKPMDNQKNTVTAQGREDRRENTAIVIQNCRIVPEEVLFPLRFKIPSYLGRPWKTYARTVIMESELGDFIQPAGWLPWSGNFALDTLYYAEYGNRGPGAATNQRVRWKGYHVINRNDAVQFTAGPFLLADRWLKTTGIPYFAGLKT 566          

Query:  118 GKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLG-PFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKI-IPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGM 1710
            G    +  S   K ++ +C   DYK+ CE  + K A + T PK  +K     A  + +     +  L   + + +   A ++CK L + A  +LGD+  +LG   +  K+ + V  L  WLSA ++Y+QTC+DGF +  G   + + + L+ S+E TSN LAM+S    LF  L +        +AAT ++     + K   P W+ +    +       L P+V V+K G G YKTI+EAL+ IP+  E + +VIYVKEGVYDE V   K M NV + GDG  K+V+TG KN+AD             G+ F+AK +GF NTAG   HQAVA RVQ+D +IF NC  +GYQ TLY QTHRQFY+ C ISGT+DFIFGDAAA+FQNC + VRKPLENQ   VTA GR D +  + ++LQNC I  ++  +  K   K YLGRP    +R IVM S I+D+I P+GW +W G     T ++ E+ N+G GA+   RV W G KK+  ++A  +T G F+ G  W++  GVP   G+
Sbjct:   83 GPPKSKTPSNGQKILKEMCSAADYKEKCEGIIEK-ARDETKPKAFIKTAISAASDEAKSAYSKTAELTFNSPEEKG--AFEDCKVLFDDAKGELGDAVSQLGNSIESGKVRTGV--LNSWLSAVISYQQTCVDGFPD--GKLKSDLEKMLQASKEFTSNSLAMLS----LFNQLQLPGA-----EAATGSNRRLLSQDKSGFPTWMSHEDRRMLKKNDEKLTPNVTVAKDGSGNYKTISEALEKIPEKYEGR-YVIYVKEGVYDETVTVTKKMPNVTMYGDGSQKSVVTGNKNFADKVRIFQTAPFAVLGEGFMAKSMGFRNTAGPEKHQAVAARVQADRAIFLNCRFEGYQSTLYAQTHRQFYKSCVISGTVDFIFGDAAAIFQNCLIYVRKPLENQQNTVTAQGRTDKQETTGIVLQNCKIMPDKDLEPVKSQFKTYLGRPSKEFSRTIVMDSTIEDLIHPDGWTQWEGDFALKTLYYAEYNNKGPGAKTDNRVKWDGYKKIDKQEAMHYTVGPFLKGHAWLMGVGVPARFGL 600          

Query:  652 RRLLQ-DAATATDENRFQRAKIIPAWI--DNRRL--DLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            RRLLQ DA        F+     P W   + R+L     T+ P   KPD++V+K G G YKTI EALK +PK    + F+IY+KEG+Y+EH+   + MTNVM+IGDG  KT ITG KN+ DG            GD+F+  D+GFEN+AG   HQAVALRV +D +IFY C+MDGYQDTLYT   RQFYRDCTISGTIDF+FGDA A+FQNC  ++RKPL NQ+C+VTA GR + R PSA+I+QN TI+ +  Y   K+ NKAYLGRPW   +R I+M S IDDVI PEGW+ W G     TC++ E GN G  A  ++RVTW G+KK+T   AADFT G+F  GD+WI  SGVPY+ G+ T
Sbjct:  324 RRLLQFDAFPVIGHGEFED----PKWYGGEGRKLLTTSTTSAPKINKPDIIVAKDGSGSYKTITEALKHVPKYGN-ETFIIYIKEGIYNEHILVTRSMTNVMMIGDGANKTRITGNKNFVDGTTTYHTATVAIQGDHFMVMDIGFENSAGPEKHQAVALRVSADKAIFYRCSMDGYQDTLYTHAQRQFYRDCTISGTIDFVFGDATAIFQNCTFLIRKPLPNQSCIVTAQGRKERRQPSAIIIQNSTITADPDYFPVKDENKAYLGRPWKEYSRTIIMDSYIDDVIQPEGWLPWEGEWGLKTCFYAELGNTGPAANKARRVTWRGIKKITENHAADFTPGRFFRGDKWIRLSGVPYIPGLTT 680          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVT-DPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPF-DFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTG--DAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALN--IKTGRRLLQ-DAATATDENRFQRAK 711
            +KG+S       S KAI++ICQPTDYK+ C D+LS  + N T DP +L+  GF+VA+  + +  K S  L++L KD R + AL  C+EL+E A+ +L  S  +LG   D TK +  + DLKVWLSA +TY+++CLD F+NTT   DA  +M+  LKTS  L+SN LAMVS+V + F  LN    + RRLLQ DA      + F+  K
Sbjct:   50 NKGRS--HDKPASMKAIKAICQPTDYKQECLDSLSYASGNTTTDPVQLIGYGFKVAMKYVYDAAKKSDFLRKLEKDPRTSNALDTCEELMELALGELRQSLVRLGFIDDLTKFNDMLMDLKVWLSATITYQESCLDAFENTTSSTDAAEEMKNVLKTSMHLSSNALAMVSQVFSAFTDLNNPDPSHRRLLQFDAFPVIGHSEFEDPK 254          

Query:  142 STSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRF--QRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSG 1689
            S S K ++ +C  TDYK  CE  + K  +  T P   +K        + + V   +  L   + + +   A ++CK L E A+++LGD+  ++G  +       +  L  WLSA ++Y+QTC+DGF +  G   + + + L+TS+E TSN LAM+S ++ L          +L    A A    R   Q     P W+ +    +       L P+V V+K G G YKTI+EAL+ +P+  E + +VIYVKEGVY E V   K M NV + GDG  K++ITG KN ADG            G+ F+AK +GF NTAG    QAVA RVQ+D +IF NC  +GYQ+TLY QTHRQFY+ C ISGT+DFIFGDAAA+FQNC + VRKPLENQ   VTA GR D R  + ++LQNC I  ++  +  K   K YLGRPW   +R IVM+S I+D+I  +GW  W G     T ++ E+ N+G G +   RV W G KK+  E+A  +T G F+ G  W+   G
Sbjct:   87 SNSKKILKEMCSATDYKDKCEGIIEKX-NGETKPMAFIKTAISATSDEAKSVYXKTAELTFSSPEEKG--AFEDCKGLFEDAMEELGDAISQVGN-NTESGKVRIGVLNSWLSAVISYQQTCVDGFPD--GKLKSDLEKMLQTSKEFTSNSLAMLSLLNQL----------QLPSTGAAAGSNRRLLSQDKSGFPNWMSHEDRRMLKKNDKKLTPNVTVAKDGSGNYKTISEALEKMPQKYEGR-YVIYVKEGVYXETVTVTKKMPNVTMYGDGSQKSIITGNKNXADGVRTFQTAPFAALGEGFMAKSMGFRNTAGPEKRQAVAARVQADRAIFLNCRFEGYQETLYAQTHRQFYKSCXISGTVDFIFGDAAAIFQNCLIYVRKPLENQQNTVTAQGRTDKRETTGIVLQNCQIMPDKDLEPVKSQFKTYLGRPWKEFSRTIVMESTIEDLIHXDGWTPWEGDFALKTLYYAEYNNKGPGXKTDNRVKWDGYKKINKEEAMQYTVGPFLKGHAWLKVEG 589          

Query:  451 YVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLD 1338
            Y  D++ WLSAAMT+++TC D   +      +++ + +  + E  SN LA+V+ +S     +N +T                 ++  + P WI      L  AT  T K + VV+K G G YKT++EA+           FVI+VK GVY+E +  +K    + LIG+G   T+ITG  + A+G            GD FIA+D+GF+NTAG  G QA+AL + SD S+ Y C+  GYQDTLY    RQFY +C I GTIDFIFG+AAAV Q+C +++RK     A  + A+GR D
Sbjct:  671 YKHDIQTWLSAAMTFQETCXDYAADHQAVNISQIGKRIXDASESVSNLLALVNRISN--HHINAET-----------------EKQGVFPKWISPGDRKLLQAT--TXKANAVVAKDGSGDYKTVSEAIGAASGGR----FVIHVKAGVYEEKIRTNKD--GITLIGEGKDSTIITGDFSVANGATMPGSATFTITGDGFIARDIGFQNTAGPQGEQALALYIASDHSVLYRCSXVGYQDTLYALAFRQFYIECDIYGTIDFIFGNAAAVLQSCNLVLRKNKGYNA--ILANGRTD 937          

Query:  118 GKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSK-VASNVTDPKELVKAGFQVAIGQLREVIKNSTT---LKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            G S G   STS KA+   C  T Y+ +C  +LS  V SN   P+EL K   QVAI +L +   + +    L   AKD ++  AL++C++LL  A+D L D+       D   L    +DL  WLS++ TY+QTC++GF    G+   K+  +LK S ELTSN LA+VS +S +  ++ +   RRLL      TD      ++ +P W+  +   L  ++ L  K D+VV++ G GKYKTI++ALK +P N   K  +IYVK+GVY  +V  +K   NV+++GDG T T+++ + N  DG            G  FIA+D+GF NTAG   HQAVAL   +D S+FY C++D +QDTLY  ++RQFYR+C I GT+DFIFG++A V QNC ++ + P+  Q   +TA G++D    + + + NC+I      D    K YLGRPW + +  + MQ+ +  +I P GWM W GT+  +T ++ EF N G G+    RV W G++ +    A+ FT   F+ G +WI  +GV Y
Sbjct:   57 GNSKGSGISTSVKAV---CDVTLYQDSCYSSLSPLVNSNNVKPEELFKLAVQVAINELTKAASHFSAGGVLNATAKDRKSVAALKDCQDLLSLALDHLNDTLS-----DANSLVDVFDDLTTWLSSSGTYQQTCIEGFDEVKGELKDKVIGYLKNSTELTSNSLAIVSWISKILNSVKL---RRLLTHP-DPTDSY----SQGVPEWLHRKDRKLLQSSDLRKKADIVVARDGSGKYKTIHDALKAVP-NKSKKRTIIYVKKGVYYGNVRVEKSKWNVLVVGDGSTATIVSAKLNVVDGTPTFSTATFAVFGRGFIARDIGFRNTAGPAKHQAVALMSTADQSVFYRCHIDAFQDTLYAHSNRQFYRECNIYGTVDFIFGNSAVVLQNCNIMPKVPMPGQQNTITAQGKIDPNQNTGISIHNCSIXPFG--DLSXVKTYLGRPWKNHSTTVYMQTYMGSLINPNGWMPWVGTSAPDTIFYSEFQNXGPGSSTXNRVKWKGLRSINQXXASKFTVHSFLQGTKWISDAGVTY 568          

Query:  130 GEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            G   STS KAIQ+ICQPTDYK+ C ++L+   +N +DPKELV+  FQVAI Q+   ++NSTTL++L KD R   AL+NC EL++YAIDDL +SF+KLG FD +K+D YVEDLK+WLS A+TY++TCLDGF+NTTGDAG KM+  LK++ ELTSNGLAM+ E+S++   L I    RRLL D  +   E R     + P+W    +  L  ATP T+KP+V+V++ G GKYKTINEAL +IPKN     FV+YVKEGVY E V F K MTNVMLIGDGPTKT I+G  N+ DG            G  F+AKD+GFEN AGA  HQAVALRV SD++IFYNC MDGYQDTLY   HRQFYRDCTI+GTIDFIFGD+A VFQNC ++VRKPL+NQ C+VTA GR + R P+ ++LQNCTIS    Y   K   K+YLGRPW + +R I+MQSQIDD+I+PEGW+ W G    NTC++ E+GNRG  +  + RVTW G+K++T +   DFT G+FI G  W+  SGVPY + MM
Sbjct:   55 GGGISTSVKAIQAICQPTDYKEACVNSLTSAKANTSDPKELVRTAFQVAINQISSALQNSTTLRDLEKDPRTKGALENCHELMDYAIDDLRNSFNKLGVFDISKIDDYVEDLKIWLSGALTYQETCLDGFENTTGDAGEKMKALLKSAGELTSNGLAMIDEISSVLTNLQIPGISRRLLSD-ESGKGEYRSDEGGLYPSWASVGQRKLFQATPDTIKPNVIVAQDGSGKYKTINEALVEIPKNGNT-TFVLYVKEGVYKEQVNFTKSMTNVMLIGDGPTKTTISGSLNFIDGIGTFRTATVAAVGSNFMAKDIGFENNAGASKHQAVALRVGSDMAIFYNCRMDGYQDTLYVHAHRQFYRDCTITGTIDFIFGDSAVVFQNCLILVRKPLDNQQCIVTAQGRNERREPTGIVLQNCTISAADDYIPFKTKFKSYLGRPWKAFSRTIIMQSQIDDLISPEGWLPWMGDFGLNTCFYAEYGNRGPASATTSRVTWRGIKQITGQHVNDFTVGRFISGHLWLGASGVPYTSDMM 583          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRHKG------KSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            KKK A+IG                    + KG           Q STSTK+IQ+ICQPTDYK+TCED+L+K A N +DP +LV+AGFQVAI  L+  I+NSTTLKE+AKD  A QAL NCKEL+  AI DL  SF ++G FD +KLD YV +LK+WLSA +TY+QTCLDGF NTTG AG KM++ L TS +LTSNGLAMV+ +S++ + L++   TGR+LL     A   + F      P+W+   +  L   TP T+KP++VV++ G G+YKTINEA+K+IPK+     FV+Y+KEGVY E V F + +T++MLIGDGPTKT ITG  ++A G            G +F+AKD+GFEN+AGA GHQA+AL+VQSD+S+FYNC +DGYQ+TL++ T+RQFYR+CTI+GTIDFI GDAAAVFQNCKM+VRKPLENQ C +TA GR + R P+  +LQNCTI+ E+ Y   K  + ++LGRPW   +R IVMQS IDD+I P+GW  W GT   +TC   E+GNRG GA L+ RVTW G+ KL+P+ A  FTAGKF+ GD WI  +GVPY +GMM
Sbjct:   17 KKKFAVIGVSSIILVAMVVAVAVGVNDGKEKGGESSPLSGSSGQLSTSTKSIQAICQPTDYKQTCEDSLNKAAGNTSDPHKLVQAGFQVAIDALKVAIENSTTLKEVAKDPMAKQALDNCKELMNTAISDLKTSFQQVGDFDISKLDEYVANLKIWLSATITYQQTCLDGFDNTTGPAGQKMKEILSTSSQLTSNGLAMVTGLSSILQDLDLSGLTGRKLL-----AQGNDNF------PSWLSPAKRRLLAQTPATIKPNMVVAQDGSGQYKTINEAIKNIPKSGN-STFVLYIKEGVYKEVVTFSRSLTHIMLIGDGPTKTKITGDLSFAGGVQIYKTATVSVSGSHFMAKDIGFENSAGATGHQAIALKVQSDMSVFYNCQIDGYQNTLFSHTYRQFYRECTITGTIDFISGDAAAVFQNCKMVVRKPLENQRCTITAQGRNNTREPTGFVLQNCTITAEKDYLPVKLDSPSFLGRPWKPYSRTIVMQSSIDDIIDPKGWAPWMGTFGIDTCSLSEYGNRGPGATLTSRVTWKGIVKLSPQDAEAFTAGKFLEGDSWIAATGVPYTSGMM 577          

Query:  118 GKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMM 1713
            G   G   STS KAIQ+ICQPTDYK+ C ++L+   +N +DPKELV+  FQVAI Q+   ++NSTTL++L KD R   AL+NC EL++YAIDDL +SF+KLG FD +K+D YVEDLK+WLS A+TY++TCLDGF+NTTGDAG KM+  LK++ ELTSNGLAM+ E+S++   L I    RRLL                     +  R+L    ATP T+KP+V+V++ G GKYKTINEAL +IPKN     FV+YVKEGVY E V F K MTNVMLIGDGPTKT I+G  N+ DG            G  F+AKD+GFEN AGA  HQAVALRV SD++IFYNC MDGYQDTLY   HRQFYRDCTI+GTIDFIFGD+A VFQNC ++VRKPL+NQ C+VTA GR + R P+ ++LQNCTIS    Y   K   K+YLGRPW + +R I+MQSQIDD+I+PEGW+ W G    NTC++ E+GNRG  +  + RVTW G+K++T +   DFT G+FI G  W+  SGVPY + MM
Sbjct:   33 GTVAGGGISTSVKAIQAICQPTDYKEACVNSLTSAKANTSDPKELVRTAFQVAINQISSALQNSTTLRDLEKDPRTKGALENCHELMDYAIDDLRNSFNKLGVFDISKIDDYVEDLKIWLSGALTYQETCLDGFENTTGDAGEKMKALLKSAGELTSNGLAMIDEISSVLTNLQIPGISRRLL---------------------VGQRKL--FQATPDTIKPNVIVAQDGSGKYKTINEALVEIPKNGNT-TFVLYVKEGVYKEQVNFTKSMTNVMLIGDGPTKTTISGSLNFIDGIGTFRTATVAAVGSNFMAKDIGFENNAGASKHQAVALRVGSDMAIFYNCRMDGYQDTLYVHAHRQFYRDCTITGTIDFIFGDSAVVFQNCLILVRKPLDNQQCIVTAQGRNERREPTGIVLQNCTISAADDYIPFKTKFKSYLGRPWKAFSRTIIMQSQIDDLISPEGWLPWMGDFGLNTCFYAEYGNRGPASATTSRVTWRGIKQITGQHVNDFTVGRFISGHLWLGASGVPYTSDMM 543          

Query:  136 QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDN-RRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            Q ST++K+I++ICQPTDY++TCE++LSK A N TDP +LV+AGF+V I  L+  I  STTLKELAKD  A+QAL NC+EL++ AI +L  SFD +  F  ++ D YV +LKVWLSA +TY++TCLDGF+NTTG AG KM++ L  S +LTSNGLAMV  V+++ K LNI   T RRLL+    A DE         P+W++  +R+ L   TP T+K D +V++ G G+YKTI EA++ IPK    + FVIY+KEGVY E V   +  T+V++IGDGPTKT ITG  NYA+G            GD+F+AKD+GFEN+AGAIGHQAVALRVQ+D+S+FYNC +DGYQDTLY  T RQFYRDCTI+GTIDFIFGDA AVFQNCK++VRKPL+NQ C+VTA GR + R P+  ++QNCTI+ +  Y   +  NKAYLGRPW  L+R IVMQS IDD+IAPEGW+ W G+   NT ++ E+ N+G GA  + RV W+G+KKLTPE A  +TA KFI GD WI  +GVPY AGM++
Sbjct:   52 QISTTSKSIKAICQPTDYRETCEESLSKAAGNTTDPSKLVQAGFKVTIEALQNAINRSTTLKELAKDPMASQALDNCRELMDDAIAELEHSFDLIESFQASQFDEYVNNLKVWLSATITYQRTCLDGFENTTGSAGEKMKELLMASSQLTSNGLAMVDGVTSILKDLNIPGLTSRRLLE----ADDE--------FPSWVNGGKRMLLLKETPATIKADAIVAQDGSGQYKTIAEAIEKIPKKKN-ETFVIYIKEGVYKEQVSLARSHTHVLMIGDGPTKTKITGNLNYANGVQTFKTATVSISGDHFMAKDIGFENSAGAIGHQAVALRVQADMSVFYNCQIDGYQDTLYAHTKRQFYRDCTITGTIDFIFGDAIAVFQNCKLVVRKPLDNQQCIVTAQGRNETREPTGFVIQNCTITADPQYFPVRLQNKAYLGRPWRELSRTIVMQSHIDDLIAPEGWLPWLGSFGLNTLFYSEYNNKGQGAVETNRVKWAGIKKLTPEAADGYTAAKFIQGDEWIPQTGVPYTAGMIS 570          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRH-KGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKT-GRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELN--KAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            KKK+AIIG                        G +  ++ S+S KAIQ+ICQPTDYK  C ++L+  A N TDPK+LV+A F  A+  L    KNST L+EL KD RA+QALQNC++L+ YAIDDL  SF+++G FD++K+D+ + D+K+WLSA +TY++TCLDGF+NTTGDAG KMRQ LKTS EL+SNGLA+V EVS++   L +    RRLL D     D +        P W  +    L  A    LKP++ V+K G G +KTINEA++ +PK +  + F++Y+K+G+Y+E V  +K  TN+M++GDGPTKT ITG  N+ DG            GD FIAK +GFEN+AGA  HQAVALRVQSD SIFYNC MDGYQDTLYT T RQFYRDCTISGTIDFIFGDAA +FQNC  +VRKPL+NQ C+VTA GR + R PSA+I+QN T + +  Y    N  K+YLGRPW   +R I+M+S I+D+I P GW+ W G     TC++ EF NRG GA+   RV W G+K + P  A DF  G+F+ GDRWI  +GVPY +G+ T
Sbjct: 1124 KKKLAIIGFSSIFLVAMVIAVIASVSSSSSDSGNAQKQEISSSMKAIQAICQPTDYKDACVNSLTSKAGNTTDPKDLVQAAFASAMEHLSAAAKNSTLLQELNKDPRASQALQNCEDLVNYAIDDLKKSFNQVGDFDYSKMDNIIADIKIWLSAVITYQETCLDGFENTTGDAGEKMRQILKTSMELSSNGLAIVGEVSSILSNLQLANLNRRLLSDDPADPDNHIDDE---FPYWSHSEGRKLLQANVSELKPNLTVAKDGSGDFKTINEAIRQLPKFSN-QTFILYIKKGIYEEQVQINKTFTNLMMVGDGPTKTKITGSLNFVDGTPTFKTATVAVLGDGFIAKGIGFENSAGAAKHQAVALRVQSDRSIFYNCQMDGYQDTLYTHTKRQFYRDCTISGTIDFIFGDAAVIFQNCTFVVRKPLDNQQCIVTAQGRKERRQPSAIIIQNSTFTADPEYYPYRNELKSYLGRPWKEFSRTIIMESYIEDLIQPSGWLPWAGDFALRTCFYTEFRNRGPGAKTHDRVKWRGIKTIKPSHAIDFAPGRFLSGDRWIPSTGVPYNSGLFT 1687          

Query:  133 EQTSTSTKAIQSICQPTDYKKTCEDNLSKVAS-NVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVE-DLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTL-FKALNIKTGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAAD-FTAGKFIFGDRWILPSGVPYVAGM 1710
            E  S  T  IQ+  +  +Y        +++ S     P  ++ A  +  + + R  ++  T    L+   R   A+++CKELL++++ +L  S  ++        +   E +LK WLSAA++ + TCL+GF+ T     + +R  LK   +L SN LAM  ++ +L FK     T +   QD                P W+ +   DL  A P  +  D +VS  G G Y++I +A+ + P  +  + ++IYVK+GVY E++   K  T +M++GDG   TV+TG +N+  G            G  FIA+D+ F NTAG    Q VALRV SD S FY C+M+GYQDTLY  + RQFYR+C I GTIDFIFG+ AAV QNCK+  RKPL  Q   +TA GR   +SP     Q+   S +  Y       YLGRPW   +R + + + +  ++ P GW+EW G     T ++GE+ N G GA LS RV W G  K+     A+ FT G+FI G  W+  +GV + AG+
Sbjct:  597 ELNSFQTLIIQACAKVENYSSCVSSIHNELESMGPRSPSSILTAALKTTLNEARIAVQMVTRFNALSSSYREQIAIEDCKELLDFSVSELAWSLLEMKSIRAGSTNVQSEGNLKAWLSAALSNQDTCLEGFEGTDRRIESFIRGSLKQVTQLISNVLAMYVQLHSLPFKPPRNSTEKSPSQD---------------FPKWMTDGDKDLLLAHPNQMGVDTIVSLDGSGHYRSIAQAIYEAPSYSNRR-YIIYVKKGVYKENIDMKKKKTKIMIVGDGIGATVVTGNRNFMQGWTTFRTATVAVSGKGFIARDITFRNTAGPKNFQGVALRVDSDQSAFYRCSMEGYQDTLYAHSLRQFYRECDIHGTIDFIFGNGAAVLQNCKIFTRKPLPLQKVTITAQGR---KSPD----QSTGFSIQDSYVYATQPTYLGRPWKQYSRTVFLNTYMSSLVQPRGWLEWNGNFALGTLYYGEYRNYGPGALLSGRVQWPGYHKIQDTSVANFFTVGRFIDGLSWLPSTGVRFSAGL 1103          

Query:   25 KKKIAIIGXXXXXXXXXXXXXXXXXXXXRH-KGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIKT-GRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYDKELN--KAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMT 1716
            KKK+AIIG                        G +  ++ S+S KAIQ+ICQPTDYK  C ++L+  A N TDPK+LV+A F  A+  L    KNST L+EL KD RA+QALQNC++L+ YAIDDL  SF+++G FD++K+D+ + D+K+WLSA +TY++TCLDGF+NTTGDAG KMRQ LKTS EL+SNGLA+V EVS++   L +    RRLL D     D +        P W  +    L  A    LKP++ V+K G G +KTINEA++ +PK +  + F++Y+K+G+Y+E V  +K  TN+M++GDGPTKT ITG  N+ DG            GD FIAK +GFEN+AGA  HQAVALRVQSD SIFYNC MDGYQDTLYT T RQFYRDCTISGTIDFIFGDAA +FQNC  +VRKPL+NQ C+VTA GR + R PSA+I+QN T + +  Y    N  K+YLGRPW   +R I+M+S I+D+I P GW+ W G     TC++ EF NRG GA+   RV W G+K + P  A DF  G+F+ GDRWI  +GVPY +G+ T
Sbjct:   13 KKKLAIIGFSSIFLVAMVIAVIASVSSSSSDSGNAQKQEISSSMKAIQAICQPTDYKDACVNSLTSKAGNTTDPKDLVQAAFASAMEHLSAAAKNSTLLQELNKDPRASQALQNCEDLVNYAIDDLKKSFNQVGDFDYSKMDNIIADIKIWLSAVITYQETCLDGFENTTGDAGEKMRQILKTSMELSSNGLAIVGEVSSILSNLQLANLNRRLLSDDPADPDNHIDDE---FPYWSHSEGRKLLQANVSELKPNLTVAKDGSGDFKTINEAIRQLPKFSN-QTFILYIKKGIYEEQVQINKTFTNLMMVGDGPTKTKITGSLNFVDGTPTFKTATVAVLGDGFIAKGIGFENSAGAAKHQAVALRVQSDRSIFYNCQMDGYQDTLYTHTKRQFYRDCTISGTIDFIFGDAAVIFQNCTFVVRKPLDNQQCIVTAQGRKERRQPSAIIIQNSTFTADPEYYPYRNELKSYLGRPWKEFSRTIIMESYIEDLIQPSGWLPWAGDFALRTCFYTEFRNRGPGAKTHDRVKWRGIKTIKPSHAIDFAPGRFLSGDRWIPSTGVPYNSGLFT 576          

Query:  112 HKGKSGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK-TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGYD--KELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPY 1698
            HK K    + S S KAI+++CQPT YK+TCE +L+K A N TDPKEL+K  F++A  Q+    K S TL EL KD R   AL +CKEL+  +I++L  S +K+  FDF++LD  + D+K WLSAA+TYE+TCLD F+NTT +AG KM++ LKT+ E++SNGL +VS +S++   L I    RRLLQD           +A   PAWID     L +A P  +KPD+VV+K G G YKTI EAL  IPK +  + FV+Y+KEG+Y+E+V F++ MTN+++IGDGP KT ITG KN+ DG            GD F+A+++GFEN+AGAI HQAVALRV SD ++FYNC+MDGYQDTLYT   RQFYRDCT+SGTIDF+FGDA  VFQNC  +VRKPLENQ C+VTA GR   R PSA+I+QN TI+     +  K+  K+YLGRPW   +R I+M++ IDD+I PEGW  W G+    TCW+GE+ N G G+++  RV W+G+K ++ + A DFT G+F+ GD WI P+GVPY
Sbjct:   51 HKSK----EVSASMKAIKTLCQPTYYKQTCERSLAKSAGNTTDPKELIKIAFKLAEKQIDSASKKSLTLLELEKDPRTRGALNSCKELMTMSINELRSSLEKVADFDFSQLDELMADIKTWLSAAITYEETCLDAFENTTTNAGEKMKKALKTAMEMSSNGLDIVSGISSVLTDLQIPGVSRRLLQDDIPVAGHGDISQA--FPAWIDPGTRRLLSAPPSNIKPDLVVAKDGSGDYKTILEALPQIPKKSN-ETFVLYIKEGIYEEYVEFNRSMTNLVVIGDGPDKTRITGSKNFVDGINTYRTATVAVIGDNFVARNIGFENSAGAIKHQAVALRVSSDYAVFYNCSMDGYQDTLYTHAKRQFYRDCTVSGTIDFVFGDAPVVFQNCTFLVRKPLENQQCIVTAQGRKARRQPSAIIIQNSTITAHPELEPVKDQYKSYLGRPWKEFSRTIIMETFIDDLIQPEGWSPWFGSFGLKTCWYGEYNNYGPGSDMKNRVKWNGIKPVSRQHAIDFTPGRFLRGDSWIKPTGVPY 575          

Query:  112 HKGKSGGE-QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +K  +GGE + +TS KAI+ +C PTDYK+TCED L K A N +DP ELVK  F   + Q+ +V K S T+ EL KD R   AL  CKEL++YAI +L  SF++LG F+F K+D  +  L++WLSA +++EQTCLDGFQ T G+AG  +++ LKT+ +LT NGLAMVSE+S     + I     RRLL                  P+W+D R   L  A    +K D+VV++ G G+YKTINEAL  +PK      FV+++K G+Y E+V  ++ MT+++ IGDGP KTVI+G K+Y DG            GD+FIAK++GFENTAGAI HQAVA+RV SD SIFYNC  DGYQDTLY  +HRQFYRDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  +LQ CTI GE  Y   KE +KAYLGRPW   +R I+M + I D I PEGW  W G    NT ++ E  N G GA ++KRVTW G+KKL+ E+   FT  ++I GD WI   GVPY+ G+ TG
Sbjct:   39 NKSDNGGEGEITTSVKAIKDVCAPTDYKETCEDTLRKDAKNTSDPLELVKTAFNATMKQISDVAKKSQTMIELQKDPRTKMALDQCKELMDYAIGELSKSFEELGRFEFHKVDEALIKLRIWLSATISHEQTCLDGFQGTQGNAGETIKKALKTAVQLTHNGLAMVSEMSNYLGQMQIPEMNSRRLLSQE--------------FPSWMDGRARRLLNAPMSEVKLDIVVAQDGSGQYKTINEALNYVPKKKNT-TFVVHIKAGIYKEYVQVNRSMTHLVFIGDGPEKTVISGSKSYKDGITTYKTATVAIVGDHFIAKNIGFENTAGAIKHQAVAIRVLSDESIFYNCKFDGYQDTLYAHSHRQFYRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLLNQACPITAHGRKDPRESTGFVLQGCTIVGEPDYLAVKENSKAYLGRPWKEYSRTIIMNTFIPDFIPPEGWQPWLGDFGLNTLFYSEVQNTGPGAPITKRVTWPGIKKLSEEEILTFTPAQYIQGDAWIPGKGVPYIPGLFTG 564          

Query:  124 SGGEQTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNRRLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +G E+ +TS KAI+ +C PTDYK+TCED L K A + +DP ELVK  F   + Q+ +V K S T+ EL KD RA  AL  CKEL++YAI +L  SF++LG F+F K+D  +  L++WLSA +++EQTCLDGFQ T G+AG  +++ LKT+ +LT NGLAMV+E+S     + I     RRLL                  P+W+D R   L  A    +KPD+VV++ G G+YKTINEAL  +PK      FV+++KEG+Y E+V  ++ MT+++ IGDGP KTVI+G K+Y DG            GD+FIAK++ FENTAGAI HQAVA+RV +D SIFYNC  DGYQDTLY  +HRQFYRDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  +LQ CTI GE  Y   KE +K YLGRPW   +R I+M + I D + PEGW  W G    NT ++ E  N G GA ++KRVTW G+KKL+ E+   FT  ++I GD WI   GVPY+ G+ +G
Sbjct:   45 AGDEEITTSVKAIKDVCAPTDYKETCEDTLRKDAKDTSDPLELVKTAFNATMKQISDVAKKSQTMIELQKDPRAKMALDQCKELMDYAIGELSKSFEELGKFEFHKVDEALVKLRIWLSATISHEQTCLDGFQGTQGNAGETIKKALKTAVQLTHNGLAMVTEMSNYLGQMQIPEMNSRRLLSQE--------------FPSWMDARARRLLNAPMSEVKPDIVVAQDGSGQYKTINEALNFVPKKKNT-TFVVHIKEGIYKEYVQVNRSMTHLVFIGDGPDKTVISGSKSYKDGITTYKTATVAIVGDHFIAKNIAFENTAGAIKHQAVAIRVLADESIFYNCKFDGYQDTLYAHSHRQFYRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLLNQACPITAHGRKDPRESTGFVLQGCTIVGEPDYLAVKEQSKTYLGRPWKEYSRTIIMNTFIPDFVPPEGWQPWLGEFGLNTLFYSEVQNTGPGAAITKRVTWPGIKKLSDEEILKFTPAQYIQGDAWIPGKGVPYILGLFSG 565          

Query:  109 RHKGKSGGE-QTSTSTKAIQSICQPTDYKKTCEDNLSKVASNVTDPKELVKAGFQVAIGQLREVIKNSTTLKELAKDSRANQALQNCKELLEYAIDDLGDSFDKLGPFDFTKLDSYVEDLKVWLSAAMTYEQTCLDGFQNTTGDAGAKMRQFLKTSQELTSNGLAMVSEVSTLFKALNIK--TGRRLLQDAATATDENRFQRAKIIPAWIDNR--RLDLATATPLTLKPDVVVSKKGDGKYKTINEALKDIPKNNEVKVFVIYVKEGVYDEHVFFDKHMTNVMLIGDGPTKTVITGRKNYADGXXXXXXXXXXXXGDYFIAKDVGFENTAGAIGHQAVALRVQSDLSIFYNCNMDGYQDTLYTQTHRQFYRDCTISGTIDFIFGDAAAVFQNCKMIVRKPLENQACMVTAHGRLDMRSPSALILQNCTISGERGY--DKELNKAYLGRPWTSLARAIVMQSQIDDVIAPEGWMEWTGTANHNTCWFGEFGNRGVGAELSKRVTWSGMKKLTPEQAADFTAGKFIFGDRWILPSGVPYVAGMMTG 1719
            +H G S G+ + + S KA++ +C PTDY+KTCED L K   N TDP ELVK  F V + Q+ +  K S T+ EL KDSR   AL  CKEL++YA+D+L +SF++LG F+F  LD  + +L++WLSAA+++E+TCL+GFQ T G+AG  M++ LKT+ ELT NGLA++SE+S     + I     RRLL +                P+W+D R  +L  A A    +KPD+VV++ G G+YKTINEAL+ +PK      FV+++K G+Y E+V  +K M++++ IGDGP KT+I+G KNY DG            G+YFIAK++GFENTAGAI HQAVA+RVQSD SIF+NC  DGYQDTLYT +HRQF+RDCTISGTIDF+FGDAAAVFQNC ++VRKPL NQAC +TAHGR D R  +  + Q CTI+GE  Y   KE +KAYLGRPW   +R I+M + I D + P+GW  W G     T ++ E  N G G+ L+ RVTW+G+K L+ E    FT  ++I GD WI   GVPY  G++ G
Sbjct:   40 KHDGDSKGKAEVNASVKAVKDVCAPTDYRKTCEDTLIKNGKNTTDPMELVKTAFNVTMKQITDAAKKSQTIMELQKDSRTRMALDQCKELMDYALDELSNSFEELGKFEFHLLDEALINLRIWLSAAISHEETCLEGFQGTQGNAGETMKKALKTAIELTHNGLAIISEMSNFVGQMQIPGLNSRRLLAEG--------------FPSWVDQRGRKLLQAAAAYSDVKPDIVVAQDGSGQYKTINEALQFVPKKRNT-TFVVHIKAGLYKEYVQVNKTMSHLVFIGDGPDKTIISGNKNYKDGITTYRTATVAIVGNYFIAKNIGFENTAGAIKHQAVAVRVQSDESIFFNCRFDGYQDTLYTHSHRQFFRDCTISGTIDFLFGDAAAVFQNCTLLVRKPLPNQACPITAHGRKDPRESTGFVFQGCTIAGEPDYLAVKETSKAYLGRPWKEYSRTIIMNTFIPDFVQPQGWQPWLGDFGLKTLFYSEVQNTGPGSALANRVTWAGIKTLSEEDILKFTPAQYIQGDDWIPGKGVPYTTGLLAG 568