ppa018272m, ppa018272m (mRNA) Prunus persica

Query:   94 VSITIHEEAST-REERLNKLR---EEAPPIQAEKVK-PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYD---ELENFQIKRDXXXXXXXXXXXXXXXXXIH----------KKLKKSIDDFVWRNSLAQN-----QQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLP--HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHN 1317
            + I + + AS+ RE+R   +    E++   Q  + K  +I +VP MLR    F   +EP V ++GP+HH  K     AE +K  +   F+ +S+Q    L  K+   I+ELR CY++ ATK Y DE LAWM+ VDGCS L FI  Y    +L++  IK                               ++  + I+ F+   S A+      + + E KP HLL+LLR  +LG   + +T+  K    +SFRNV EL+AAGI F+P                 G L LP+I +DDST+ +F+NLIAYEMCP+  N+  VTSYICFLDSLID P+DVK LR++ +L+NFLG+D+EVA+LFNEI TDLVP+ D Y  VK +I+KHY    +  +A+  H HFSSPWTV+AF           +QT Y+V   HN
Sbjct:   47 IDIVVEDNASSSREKRFKSVMGGPEDSKRSQLSETKWARIPKVPHMLRGTKDFKILFEPRVVSVGPYHH-HKHDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDEDLAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGFEEGMQMIEQFI--GSAAETDPPAVKSDNEEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILLGFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRHN 476          

Query:  670 NPEAKPTH-LLELLRTTMLGTSPS-----------EKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPN----DDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            N E+KP H LL+L R   LG   S           E     ++  SFRNV+EL  AGI  +                    L +P I +D+ST+  F+NLIAYEM  D  +DF   SY+ FLDSLIDH DDVK L+   ILQN LG  +EVAQ FN +  +L  N     D+   ++  ++ HY +     M Q    +F SPWT++A+           VQT +S
Sbjct:   26 NNESKPCHHLLDLFRRNFLGDERSGSPTHPENENLEVRDVKEVMASFRNVKELMDAGIRIKRSPTRHLRDISFRSNGITACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDF--ISYLRFLDSLIDHADDVKELQSIGILQNNLGTHDEVAQFFNTVSANLESNFHAYKDVRVKIRKHLQSHYNSKLTMWMTQCLDTYFGSPWTIIAWVGAALALFLTFVQTYFS 249          

Query:  769 SFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRV----MAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            SFRNV+EL AAGI  +                    L +P I +D+ST+  F+NLIAYEM  D  +DF   SY+ FLDSLIDH DDVK L+   ILQN LG  EEVAQ FN +  +L  N   Y  V+ +I KH  N  N      M Q    +F SPWT++A+           VQT +SV
Sbjct:   30 SFRNVKELMAAGIRIKRSPTRHLRDISFRSNGITACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDF--ISYLRFLDSLIDHADDVKELQSIGILQNNLGTHEEVAQFFNTVSANLESNFHAYKDVRVRIRKHLKNHYNSKLKMWMTQCLDTYFGSPWTIIAWVGAALALFFTAVQTYFSV 209          

Query:  196 IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTR---KPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRN-----SLAQNQQ----------------------NPEAKPTHLLELLRTTMLGTSPSEKTKGTK---------------LPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPN-DDIYYS-----VKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHN 1317
            I RVP  LR+  K    + P + ++GPFH+     +   EH  +  L+L  +   +      +L+ +  +   + R+CY      D  D     M+ +DGC  LE +  Y+  E  +   D                    KL+  +  FV +      SLA++                        NPE +  H+LE+ R+T L +   + T G +               L HS   V EL+ AG+  +                  G+L +P + +DD+T   F+N +AYE C D    F  T+Y+ F DSLI+   DV  L K  I+ + LG+D++VA LFN++G ++V + D+ Y S     V +  + +Y +          H++FS+PWT  +             QT Y+V GY++
Sbjct:   42 IYRVPRNLREVHK--NAFVPKIISIGPFHYGDPGLRFMEEHKVRYLLRLLGSRTPEKGGQAEELMSQELEQ--KTRQCYTGAFDIDSND--FVQMMVIDGCFVLELLRLYNRFEREKNVDDPIFTIRWMLRTLQRDLL---KLENQLPFFVLKKLFELISLAEDPPLIDLVLTFFDPLLPRKNIEGNLNPEGEFDHMLEVFRSTFLSSVNQDITSGCEQLKISVNVPLVQERQLIHS---VTELEKAGVKLKKREDCDLLDINFQA----GVLKIPPLYIDDNTAVLFLNFVAYEQCEDTKPFF--TNYLMFFDSLINSSADVGILHKNGIINHVLGSDQDVADLFNKLGREVVYDLDECYLSQQIKRVNNYCKTYYASKWRVWFTNLKHDYFSNPWTFFSLLAAIALLLLTTAQTYYTVYGYYS 448          

Query:  196 IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTR---KPKYEHAEKIKLKLAANF-------VKDSKQNDADLLKKVE-DNINELRKCYDEEATKDYEDEF------LAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXX---------IHKKLKKSI----------------DDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTK--GTKLPHSFRN------------VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPN-DDIYYS-----VKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            + RVP  +R   K    + P + ++GPFH+     +   EH  +  L+L  +        V+DS Q    ++K +  +++ E  +  +++  ++Y ++       L  M+ +DGC  LE +  Y + +N +   D                          + +KL + I                D  + R ++ + + NP  +  H+L++ R+T L +S +E+TK  G K      N            V ELQ AG+ F+                  G+L +P + +DD+T P F+NL+AYE C      F  T++  F DSLI+   DV  L K  I+ + LG+D++VA LFN++G ++V + D+ Y S     V D  ++++ +  +        ++FSSPWT ++             QT Y+V  Y+
Sbjct:   53 VYRVPKSMRGIQK--NAFLPKIISIGPFHNKDPGLRIMEEHKMRYLLRLLESGPRENGERVEDSAQQVPQVVKAIRLEDLAESMRMLEQKTRENYSEDLQIDSDELIQMMVIDGCFVLELLRLYFKFDNEEEVEDPIFTTRWMLRTLQRDLLKLENQLPFFVLEKLYELIRLVDDPPLVDLVVTFFDPLLPRKNI-KGKLNPNEEFDHMLDVFRSTFL-SSINERTKPAGWKQLQKLDNIPLVEERQLIHCVTELQEAGVRFKMREDLDLLDISFKD----GMLKIPPLYIDDNTVPLFLNLVAYEQCDQDAKPF-FTNFCMFFDSLINSHTDVGILHKNGIINHVLGSDKDVANLFNKLGREIVYDLDECYLSQQMMDVNDYCKQYFASKWHVWFTNLIRDYFSSPWTFLSLLAAIALLLLTTAQTFYAVYAYY 478          

Query:   91 EVSITIHEEASTREERLNKLREEAPPI---QAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDA---DLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLK-------------------KSIDDFV---WRNSLAQN----QQNPEAKPTHLLELLRTTMLGTSPSEKTKGT---KLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVK--DQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNNK 1323
            +V + I E    R  R+ +   E P +    A +    I RVP  L +     + Y+P + ++GP+H   +P  +  E+ K     + +  ++++     D L+ ++    E R+CY E    D  D FL  ML +DGC  ++F  K  ++  F+                     +  +L                     S+   V   + N+L +     Q++   K  H L+LLR + +   P E+  GT   +  H  + V +L+ AGI  +                 +G++ +P + +DD     F N +A+E+C   H D    +T+Y   LD LI+   DV HL ++ I +N+ G D  VA+  N +G D+  + D  Y  K  + + ++Y N  +  +A   + +F +PW+ ++           IVQT Y+V  Y + +
Sbjct:    7 DVVVRIWEVNKERLARMQQKISEEPRLLRKSAGRSSCCIFRVPRTLVEINS--RSYQPHIISIGPYHRG-EPHLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMEARECYSEIIHLDTHD-FLE-MLVLDGCFIIDFFRKIGKMHPFEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTKMPGEESGPSLASLVLGFFNNTLQRPDEILQKHCNLKGKHFLDLLRLSFI---PEEQELGTLDHRPTHLIQCVSKLRKAGIKLKSGKADSFLTVKFR----NGVMEMPPVTIDDFLTCFFQNCVAFELC---HKDCTKHITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVYPYFHRQ 441          

Query:  196 IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLE-FIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPT-----------HLLELLRTTMLGTSP-------------SEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPN-DDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            I R+P  LR+    DK Y P + +LGP+HH R+ +  + ++ K +   + +K +  +    L  +++   + R CY  E T          M+ +DGC  LE F       ++    R+                 I   L+  I  F    S     ++     T           H LE+ R ++L T P             S +    +       V +L+ AGI F+                 +GIL +P++ + D T+  F+NLIA+E C  D  ND  +TSY+ F+DSLI+ P+DV +L    I++++LG++ EVA LFN +  ++V + +D Y S                         S PWT+++F            QT Y+V  Y+
Sbjct:  102 IYRLPHYLREGD--DKAYIPQIVSLGPYHHGRR-RLRNMDRHKWRSLHHILKRTNHDIEIYLDAMKELEEKARACY--EGTICLSSNEFVEMMVLDGCFILELFRGVAGGFKHLGYARNDPVFAIRGSMHSIQRDMI--MLENQIPLFPLTKSDRNRLESSLGYTTTFDPLGDQGGLHCLEVFRRSLLRTGPRPVPRIWMKRWSHSNRVADKRRQQLIHCVTQLREAGIKFKKRKTDRFWDIKFK----NGILRIPRLLIHDGTKSLFLNLIAFEQCHLDCSND--ITSYVIFMDSLINSPEDVGYLHYCGIMEHWLGSESEVADLFNRLCQEVVFDINDSYLS-------------------------SFPWTIISFVAAVVLLALTFAQTFYAVYSYY 463          

Query:  112 EEASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHA---EKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKY-----------DELEN-----FQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQN-----QQNPEAKPT-HLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYS-VKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            E A++ + RL++L     P+ A      I RVP  LR+     + Y P V ++GP HH      EH    E+ KL+   NF+  +++   + ++ +       R CY E      + EF+  M+ VDGC  +E I  +           D + N     + ++RD                    ++ +  + +     L+ N      Q PEAK   H ++LL      +S   + + +       +  +L  AG+ F                   G+L +P++K+DD   P F NLIA+E C  +     +T YI  +D LI+   DV  L  K I++N LG++  V  LFN +  +     D Y + V + + ++     NR  A   H++F SPW   +           ++QT++S
Sbjct:    8 EVATSLQGRLDRLT----PLSATCC---IYRVPQKLRKVNM--EAYTPRVVSIGPLHHGE----EHLIAMEEHKLRYLQNFLHRTRKTLEECVEIISREEKTARDCYMEPINMSSK-EFVE-MILVDGCFIIEVILGFQNWNGRTGKPDDRIFNKPWLIYDVRRDMTLLENQLPLFLLLTLYSQLEVPRHQNHYDSFLLLSVNFFKFYSQMPEAKKIKHFVDLLIVCQQPSSTRPQNR-SDFKFMIPSATQLHEAGVRFE-LGSKEERLLDIVYRRSDGVLKIPRLKLDDKCEPLFRNLIAFEQC-HYRERLYITDYITLMDQLINTTKDVDVLVNKGIIENLLGDNVAVTNLFNNLLINATTGTDFYLADVTEGLSEYCDVPWNRWKAALRHDYFCSPWRGASTIAAVILLLLTLIQTIFS 411          

Query:  742 WATEMLMKELSHHSVTPVTVVLFYLVFNRVVNVIVRHQVSAYFIEELSHLLVIPKEVLKYQLFPQMLYIIRMIDERIEEAYVRGDPEIIVEIGTHFVGYQVHELGSGRVVYFYLRKIKDSMA*RRNKRYAPQ*VAITRPKMDPGCLKLLHVAKRVGKFSTFCF 1230
            W  EM++K LS+ S+  + VVL   +F   +++ + +QV A  +E L H+++  K+V++  L  Q+L I+ MI+E ++EAYVR D  +I  I THF+GY V ELG   V+  Y  K + +      +R   Q    TR ++DPG  KLL V+KR+     + F
Sbjct:   26 WRPEMVVKGLSYPSIHSLLVVLLNTIFYIFISIGI-YQVIADLVENLGHIVIAAKKVVENVLRSQLLDIVCMINEVVKEAYVRSDRIVIWGIWTHFIGYHVQELGLREVINGYWGKFQVAKEEVGFERNVSQETRSTRFEIDPGSFKLLDVSKRLPNAPLYAF 187          

Query:  196 IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHA---EKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQ--------------IKRDXXXXXXXXXXXXXXXXXIHKK----LKKSIDDFVWRNSLAQNQQ-NPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYY--SVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            I RVP  LR+     + Y P V ++GP HH      EH    E+ KL+    F+ ++++   + ++ +     + R  Y  E+ K   +EF+  M+ VD C  +E I  +    + +              ++RD                   +     L ++ +D+   + L  +++ +   +  H ++LL   +  +S S   +             L+ AG+ F+                 +G+L +P + + +     F NLIAYE C D H    +T Y+  +D LI+   DV  L +K I+ N LG++  V  LFN +  D     + ++   + +++ K+Y +  NR  A   H++FSSPW   +           ++QTV++
Sbjct:   29 IYRVPQKLRKANM--EAYTPRVVSIGPLHHGE----EHLVAMEEHKLRYLQKFLSETRKTLEECVEIIYREEEKARGYY-MESIKMSREEFVK-MILVDACFIIEVILGFSSSHSIETGDRIYNKPRLFIDVRRDMTLLENQLPFFLLLSLYSLRAPPGPLPENQNDYAHYSFLLLSKKISSRHEIKHFVDLLIVCLQPSSSSLPPESKSFKFVIPTATYLREAGVRFKLGSKDKDNDKLLDLDYNNGVLKIPHLILQEKCESLFRNLIAYEECHD-HAQTYITDYMYLMDHLINTTKDVNLLVRKGIISNHLGDNHAVKNLFNRLLIDTTTCKETFHFAGIYEKLNKYYDSPWNRWQATLRHDYFSSPWRGASTIAAVILLVLTLIQTVFT 411          

Query:   94 VSITIHEEAST-REERLNKLR---EEAPPIQAEKVK-PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYD---ELENFQIKRDXXXXXXXXXXXXXXXXXIH----------KKLKKSIDDFVWRNSLAQN-----QQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLP--HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHN 1317
            + I + + AS+ RE+R   +    E++   Q  + K  +I +VP MLR    F   +EP V ++GP+HH  K     AE +K  +   F+ +S+Q    L  K+   I+ELR CY++ ATK Y DE LAWM+ VDGCS L FI  Y    +L++  IK                               ++  + I+ F+   S A+      + + E KP HLL+LLR  +LG   + +T+  K    +SFRNV EL+AAGI F+P                 G L LP+I +DDST+ +F+NLIAYEMCP+  N+  VTSYICFLDSLID P+DVK LR++ +L+NFLG+D+EVA+LFNEI TDLVP+ D Y  VK +I+KHY    +  +A+  H HFSSPWTV+AF           +QT Y+V   HN
Sbjct:   47 IDIVVEDNASSSREKRFKSVMGGPEDSKRSQLSETKWARIPKVPHMLRGTKDFKILFEPRVVSVGPYHH-HKHDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDEDLAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGFEEGMQMIEQFI--GSAAETDPPAVKSDNEEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILLGFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRHN 476          

Query:   79 PAEIEVSITIHEEASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY---KYDELENFQI---KRDXXXXXXXXXXXXXXXXXIHKK------LKKSIDDFVWRNSLAQ-NQQNPEAKPTHLLELLRTTMLGTS-------------PSEKTK---------GTKLP-----------HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLG 1308
            P   E  I I+E +   +  +  LR+     +++   P+  +VP MLR    F K YEP V ++GP+HH  KP     E IK   A  F+ DS Q+   L  K+  NI  +RKCYD  +T +Y+DE LAWM+ +DGC  L+FI    K + L N QI    +D                    K      +KK I +FV +    + + +  + +P HLL LLR+++LG               P +K K         G + P           +SFR++++L+A+GIH +P                HG L LP+I +DD T+ KF+N++AYEMCPD  +D+G+TSYIC LD LIDH DDVK LR K IL N LGNDE+VAQLFNEIG DLV + + Y  VKD+I++HY    N  +AQ  H+HFS+PWT++AF           VQT Y++ G
Sbjct:   27 PEPKEHRIDINEISPRVKNWIGGLRKTEERTESQTQWPRTPKVPQMLRGTQDFKKMYEPRVISIGPYHHG-KPDLGRVEMIKPPCAQEFLADSNQDIEALYTKIRSNIETVRKCYDWSSTSEYDDEALAWMMLLDGCFLLQFIRRKGKINFLRNHQIIFVLQDLFLLENQLPYGVLKLIFEEAKFNDDSLMKKKIKEFVTKTGRPEASDEELDEEPPHLLHLLRSSLLGRDKRIRGSQPEQEQQPEKKGKSSSSQGGDWGFRCPWKKCKQRAIWLYSFRSIKDLKASGIHLKPSRTSVLTDVSFKSSFFHGYLKLPRIIIDDFTKKKFLNMVAYEMCPDAPDDYGITSYICLLDDLIDHADDVKELRSKNILYNLLGNDEDVAQLFNEIGNDLV-DPEAYEDVKDRIQEHYNKRMNTWIAQALHDHFSTPWTIIAFIAAVLILFLTGVQTYYALPG 480          

Query:  121 STREERLNKLREEAPPIQAEKVKP-KIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY------KYDELENFQI---KRDXXXXXXXXXXXXXXXXXIHKKLK--KSIDDFV---------------WRNSL----------AQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLP-HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            S+R+  L+ + E+       K +  KIQ+VP MLR D   +K ++P V ++GP+H   KP+ +  E++K +     V +SK  D DL  +V   + + RKCY E +T + +D   A M+F+DGC  L+FI       K   ++N  +   +RD                 + KK +  + I++FV               W + +          A+ +Q PE +P HLL +L   ++  S       +     S+R+  EL+AAGI F+P                 G L LP + VDDSTR   +NL+AYE CP   +DFGVTSY+CF+D LIDH +DVK LR   IL NFLGND++VA+LFNEI  DLVPN   Y  VK  IEKHY N     +A++ H HF+SPWT +AF           VQT ++
Sbjct:   54 SSRDPWLSSIMEDGGESGENKSQQSKIQKVPAMLRDDESNNKCFDPWVVSIGPYHRG-KPELQLMERLKKETVRQHVTESKVEDQDLYNRVVKVVGDARKCYKEGSTDELDDREFAQMMFLDGCFILQFICCSTDKDKKMNIKNHNVAFVRRDLFLLENQLPFLVLEALMLPKKDEWLEKINNFVDNTRAHSPDHHKQGGWLDRITKKLFREVPQAKEEQQPEQQPVHLLGILHAQLINQSDLNALSCSMSDWSSYRSANELKAAGIQFKPSKTRRFTDVNFEPALSFGTLELPPMMVDDSTRSMLLNLVAYESCPGAPDDFGVTSYLCFMDVLIDHAEDVKVLRSNGILLNFLGNDKQVAKLFNEIAKDLVPNPHAYARVKGDIEKHYNNKAKIWIAEWLHTHFTSPWTFLAFLGAILALALSCVQTYFA 483          

Query:   79 PAEIEVSITIHEEASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKY----DELENFQIKRDXXXXXXXXXXXXXXXXX-------------------IHKKLKKSIDDFVWRNSLAQNQQNPEA--KPTHLLELLRTTMLG----TSPSEKTKGTK----------LPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            P E  + + I+         + K +E  P   ++   P++ +VP MLR    F K YEP V ++GP+HH  KP     E IK   A  F+    Q+  DL  K+E  I  +RKCYD + T  Y DE L WM+ +DG   L+FI       D++ N  + RD                                    + K +K+ + DF     L+   Q  E   +P+HLLELLR+ +LG      P +K +  K          +  SFR+++EL+AAGI+ +P                +G L LP+I +D  T+ KF+N++AYEMCPD   D  VTSY+CFL  LID  DDVK LR K IL N LG+DE+VA++FNEIG DLV +   Y  VK +I+KHY    N  +A+  HEHF SPWT  +            +QT Y+
Sbjct:   29 PKEHRIDVEINPTVENWNRIVQKAKERIP---SQSQWPRLPKVPHMLRGTQDFKKLYEPRVISIGPYHHG-KPHLRPGEMIKPLYAEQFLAGINQDFKDLYTKIESKIEAVRKCYDTKPTNRYNDEALIWMMLLDGLFLLQFIGSTVDPRDDMSN--VLRDHQINFVTQDLFLLENQLPFGVLKLIFEGANFQDAPPMEKTIKEFVTDFGMPEGLSSEIQLEEENKEPSHLLELLRSALLGGYKKIQPKQKQEAEKKGKSSSSGGGIWESFRHIKELKAAGIYLKPSRKSFLTEISFKSHFFYGCLKLPRITIDGFTKTKFLNMVAYEMCPDAPVDQAVTSYVCFLYELIDQADDVKELRSKHILHNLLGSDEDVAKIFNEIGNDLV-DPGAYGDVKARIQKHYDKRVNTWIAEGLHEHFRSPWTFTSLIAAVWILIVTGLQTYYA 467          

Query:  193 KIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNS--------------LAQNQQNPEAK----------PTHLLELLRTTMLGTSPSEKTKGTKLP----------------HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            KI +VP MLR    F+K+YEP V + GP+HH  KP     E +K      F++DS Q+  +L +K+E NI  +R CYDE+ T  Y+DE LAWM+ +DGCS L FI         Q+  D                 +  +L   I + ++  +              +  N   P             P+HLL+LLR+ +LG  P  + KG                     S+RN++EL+AAGI+ +P                 G L LP I +D ST+ K +NL AYEM P+   DFGVTSYICFLDSLI + +DV  L+    L NFLG+DE+VA LFN+I  DLVPN D Y  VK  ++KHY    N  ++++ H +F    T +AF          I QT ++    H
Sbjct:   61 KIPKVPQMLRHTQDFEKFYEPRVISFGPYHHG-KPHLLQGEMLKPLCGRRFLRDSGQSIQNLYRKIESNIKLVRMCYDEDQTYKYDDEELAWMMLLDGCSLLYFILCVMRRNESQLS-DLNVKSHFVAFVQLDCFLLENQLPFGILELLFEGARLGADTMEEMIERFITSNIAKPRGTMASDLDLVKDPSHLLDLLRSGLLGPQPVPEQKGQPEGIWRGTGPREMRKQGDWQSYRNIKELEAAGIYLKPSRTTYMRDISFESYFFFGYLKLPHITIDASTKLKLLNLAAYEMSPNGPGDFGVTSYICFLDSLIKNAEDVMLLQSNYTLFNFLGSDEKVADLFNDIAKDLVPNRDAYALVKAGVQKHYNTRVNVWISKWLHSNF----TFLAFIGAVVALGSSICQTYFAAFPPH 468          

Query:  187 KPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYE---------DEFLAWMLFVDGCSTLEFIYKYDELE----NFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDD---------FVWRNSLAQNQQNPEAKPTHLL-------------ELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            +PKIQRV   LR    F+K+Y P   ++GP HH        AEK KL  AA +++++     DL KK+ DNI+EL+  +D++               +E L+WMLFVDGCS L  + K +  E    N ++ +                  + K L K  D+         F+  +  A   ++   K   ++             E  +  +   S  EK K      ++RN+Q+L+  GI+F+                    L LP+I VDDS+   F+NLIAYEMCPDFHND+G+ S+  F+DSLID+P+DVK LR K IL N LG+DEEVA+LFN I TDLVPN D Y  V+ +I  HY N  N  +AQ F  +FSSPW ++AF           +QT ++V
Sbjct:   24 RPKIQRVLKSLRNRKNFEKHYSPKCVSIGPIHH-HNTNLILAEKYKLMWAAKYIENNGYIPEDLHKKIADNIDELKGHFDDDVLTSTRWSLAGFRSLEEKLSWMLFVDGCSLLYILEKANLNEPWHMNIKVDQLVLVMMDVLLLENQLPYQVLKLLWKDEDESGLIESMMNFLDCHHWATPDESQSGKKKDMVPKRKGEGVTIRNNEANKENLSKKSRDEKVKMM----TYRNIQDLRDVGINFKSSKTRRPRDIDFSEGLFTAELTLPEIVVDDSSATTFLNLIAYEMCPDFHNDYGICSFAAFMDSLIDNPEDVKLLRSKEILLNSLGSDEEVAELFNIISTDLVPNADTYLEVRAKIHDHYRNRCNTWIAQGFRTYFSSPWAIIAFIAALIALVLTFIQTWFTV 425          

Query:  121 STREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDE---FLAWMLFVDGCSTLEFIYKYD--ELENFQIKRDXXXXXXXXXXXXXXXXXIH-----------KKLKKSIDDFVW---------------RNSLAQNQ---QNPEA-----------------KPTHLLELLRTTMLGTSPSEKTKGTKLP--------------HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGI---LYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            S + E+L K ++ A     +   PKIQRVP  LR    F K+Y P + ++GP HH  + K +  EK KL  AA +++ +KQ+   L +K+  NI +L+  + E+  +D+ D+     +WMLFVDGCS L+ + K +  + +   +K D                  H            KL KS+++F+                 NS+ +++   Q P++                  P HLL+ LR  +L   P +K K                    ++RN+QEL+AAGI  +                   +   L LPQI VDD+T P F+NLIAYEMCPDF N+F + S++ F+DSLIDHP+DVK LR   +L N LG+DE+VA+LFN I  DLVP+ + Y  V+ QIEKHY +     +A  +H +FS+PW V+AF           +QT +++
Sbjct:    8 SLKFEQLEKAKQIA-----QNSVPKIQRVPHHLRDRENFAKHYLPRLVSIGPIHHGAE-KLQLGEKYKLMWAAMYLERTKQDAQTLYQKIASNIEQLKDLFAEDVIRDFPDDEKLSWSWMLFVDGCSLLQILEKGELQDPKEMNVKVDQLVLVWQDVLLLENQLPYHVLKLLSDHEDDAKLVKSMNEFLKCHHLSPELRSKKQDIGNSMTKDEHRTQTPKSLYIIIGVLHVDMLYFHESPIHLLDQLRRYVLD-DPHKKQKNETGNVKKEDQNTNEDLDMTTYRNIQELRAAGIKLKRDKSRRRLRDVSFSYRWMCLCAELTLPQITVDDTTTPTFLNLIAYEMCPDFKNNFEICSFVVFMDSLIDHPEDVKELRAAKVLHNALGSDEDVAKLFNTISADLVPDMESYLHVRRQIEKHYRSKYRTWIALGYHTYFSNPWAVIAFHAALVVLVLTFIQTWFTI 462          

Query:  187 KPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEAT----KDYE-----DEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDXXXXXXXXXXXXXXXXX--------------IHKKLKKSIDDFVW----------------------RNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHS-----------------------FRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            +PKIQRV   LR    F+K+Y P + ++GP HH      +  EK KL  AA +++++     DL KK+ DNI+EL+  + ++      K  E     +E L+WMLFVDGCS L  + K   DE  +  IK D                               + K +   +D   W                       +S++   ++    PTHLL+L R  +L TS S KTK  +  ++                       +R++Q+L+A GI  +                    L LP+I VDD++   F+NLIAYEMCPDF ND+G+ S+  F+DSLID P+DVK LR K IL N LG+DEEVA  FN I TDLVPN  IY+ V+++I +HY N     +A  FH +FS+PW ++AF           +QT ++V
Sbjct:   24 RPKIQRVAEYLRNRKNFEKHYSPKLLSVGPIHHDNT-NLKLGEKYKLMWAAKYIENTGHIPEDLHKKIADNIDELKGHFGDDVLTLTGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDNDSELIKSMMTFLDCHHWATPDESQPDKEKDMVPKGKGEGEHSVSITNESQLETPTHLLDLQRKIILTTSNS-KTKSNEANNNKWSQKNSDENVKKNSKEDVKMMTYRSIQDLRAVGIRLKSSATRRPTDVDFSAGWFAAKLTLPEIVVDDTSAATFLNLIAYEMCPDFENDYGICSFAAFMDSLIDRPEDVKELRSKGILLNSLGSDEEVADFFNIISTDLVPNTKIYFEVREKIHEHYCNKCKTWIALGFHTYFSNPWAIIAFLAAFIALALTFIQTWFAV 463          

Query:  175 AEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDE---FLAWMLFVDGCSTLEFIYK----YDELENFQIKRDXXXXXXXXXXXXXXXXXIHK---------KLKKSIDDFVWRNSLAQNQQNPEAK-PTHLLELLRTTMLGTSPSEKTKG-------------------TKLPHS---------------------------FRNVQELQAAGIHF-RPXXXXXXXXXXXXXXXC-HGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQT 1290
            A+   PKIQRV   LR    F K+Y P + ++GP HH  + K +  EK K+  AA +++ +KQ+   L +K+  NI +L++ + E+  +D+ D+     +WMLFVDGCS L+ + K    Y +  N ++ +                  + K         KL KS+++F+   +L + +     + P HLL+ LR  +L     +K  G                    K  +S                           +RN+QEL+AAGI   R                C    L LP+I VDD+T P F+NLIAYEMCPDF N+F + S++ F+DSLIDHP+DVK LR   +L N LG+DEEVA+LFN I TDLVP+ + Y  V+ QIEKHY +     +A  +H +FS+PW ++AF           +QT
Sbjct:   13 AQNSAPKIQRVAHHLRDRKHFAKHYLPRLVSIGPIHHGAE-KLQLGEKYKVMWAAMYLERTKQDAQTLYQKIASNIEQLKELFSEDVVRDFPDDEKLSWSWMLFVDGCSLLQILEKGKLHYPKEMNVKVDQLALVWQDVLLLENQLPYQVLKLLSDHGNDAKLVKSMNEFL--KALTEEEYRSVCESPIHLLDQLRRYVLDDPHEKKDTGRDKRKKNTNEDLDMITYRNKKRENSTNEDLDMTTYRNKKKEQNTNEDLDMTTYRNIQELRAAGIKLKREKSRRLRDVSFSYRWMCLCAELMLPEITVDDTTAPTFLNLIAYEMCPDFGNNFEICSFVAFMDSLIDHPEDVKELRAAKVLHNALGSDEEVAKLFNTISTDLVPDTESYSHVRCQIEKHYRSKYRTWIALGYHTYFSNPWAIIAFHAALVALVLTFIQT 446          

Query:  139 LNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDE-----LENFQ-------IKRDXXXXXXXXXXXXXXXXXIHKK------LKKSIDDFVWRNSLAQNQQNPEAK---PTHLLELLRTTMLGTS--------------------------PSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMA 1200
            +  L+      Q++   P+I +VP +LR    F++ YEP V ++GP+HH  KP  +  E IKL+ A  F+ DS Q+   L  K+  NI  LRKCYD+  T   +DE LAWM+ +DGC  L+FI    +     L N         ++RD                    K      +++ I +FV R  +A  Q + E +    +HLL+LLR+ +LG S                          P +K K   +  SFRN++EL+AAGIH +P                 G L LP I VDDST+ +F+N++AYEMCPD  ND+ VTSY+ FL  LIDH DDVK LR + IL N LG+DE+VA++FNEI  D+V + ++Y  VK +I+K Y    N  +A
Sbjct:   48 IKSLKNAEESTQSQSSWPRIPKVPQLLRGTHDFERLYEPRVISIGPYHHG-KPHLQPVETIKLQYAQKFLADSDQDIEALYTKIGSNIEALRKCYDKIPT---DDEKLAWMMLLDGCFLLQFIRSRKDGSTVDLSNVLRIHQINFVERDLFLLENQLPFGVLQLIFEGAKFNDGSTMEQMIKNFVTR--IASLQPSSEIRLDERSHLLDLLRSAILGKSAPKQERQPDKKGKSSSSSGGDGRFCCPWKKGKQQGIRQSFRNIKELKAAGIHLQPSRTRFLTDISFNSYFFRGYLNLPPIIVDDSTKSRFLNIVAYEMCPDAPNDYTVTSYLRFLYELIDHADDVKELRSRHILINHLGSDEDVARIFNEIANDVV-DTEVYGDVKARIQKDYNKRVNTCIA 441          

Query:  241 KYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDAD---LLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLE-FIYKYDELENFQ------------IKRDXXXXXXXXXXXXXXXXXIHKKLKKSID-----DFVWRNSLAQN----QQNPEAKPTHLLELLRTTML-GTSPSEKTKG-------------------TKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDHPDDVKHLRK-KLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYY--SVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNNK 1323
            K Y+P V ++GP+H+  K   +  ++ K +L   F+ ++K+ D +   L+K V D  +++RK Y EE    ++   L +M+ +DGC  L  F+     +E  +            I+ D                 +  K+  S D        ++N + +     +++   K  HLL+L+R T L  TS S+K                      +K      + + L+  GI FR                    L +PQ++ D      F+N +A+E    F+ D    +T+YI F+  L+++ +DV  LR  KLI++N  G++ EV++ F  I  D+V   D  Y  +V   + ++   W N + A F H HF SPWT ++           ++Q+  ++L Y N+K
Sbjct:   61 KAYKPKVVSIGPYHYGEK-HLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMVFLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNPIDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKK--NKLQIPQLRFDGFISSFFLNCVAFEQ---FYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDK 462          

Query:  208 PFMLRQDTKFDKYYEPIVAALGPFHHTRK---PKYEHAEKIKLKLAANFVKDSKQNDA----DLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQ-------------------IKRDXXXXXXXXXXXXXXXXX------IHKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTML---GTSPSEKTKGTKLPHSFRN-VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLV--PNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGY 1311
            P++   DTK    Y P + ++GP+HH  K   P   H  +     A N V    ++D     D +K++E+   + R CY      +  +EF+  ML +DG   +E I+K    E FQ                   I+RD                       +  K+   +    ++  L   +   E    H L++LR  +L   GTS  + +   K P    + V EL+ AG+ F                  +G L +P++ + D T+  F+NLIA+E C    +   +TSYI F+D+LI+  +DV +L    I++N+LG+D EV+ LFN +G +++  PND    ++  ++  +Y    N + A   H++F++PW   +F            Q+ ++V  Y
Sbjct:  111 PYLQENDTKS---YMPQIVSIGPYHHGHKHLMPMERHKWR-----AVNMVMARAKHDIEMYIDAMKELEE---KARACYQGPINMN-RNEFIE-MLVLDGVFIIE-IFKGTS-EGFQEIGYAPNDPVFGMRGLMQSIRRDMVMLENQLPWSVLKGLLQLQRPDVLDKVNVQLFQPFFQPLLPTREVLTEEGGLHCLDVLRRGLLQSSGTSDEDMSMVNKQPQQLIHCVTELRNAGVEFMRKETGHFWDIEFK----NGYLKIPKLLIHDGTKSLFLNLIAFEQC-HIKSSKKITSYIIFMDNLINSSEDVSYLHHYGIIENWLGSDSEVSDLFNGLGKEVIFDPNDGYLSALTGEVNIYYRRKWNYLKATLRHKYFNNPWAYFSFIAAVTLLIFTFCQSFFAVFAY 496          

Query:  241 KYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDAD---LLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLE-FIYKYDELENFQ------------IKRDXXXXXXXXXXXXXXXXXIHKKLKKSID-----DFVWRNSLAQN----QQNPEAKPTHLLELLRTTML-GTSPSEKTKG-------------------TKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDHPDDVKHLRK-KLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYY--SVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNNK 1323
            K Y+P V ++GP+H+  K   +  ++ K +L   F+ ++K+ D +   L+K V D  +++RK Y EE    ++   L +M+ +DGC  L  F+     +E  +            I+ D                 +  K+  S D        ++N + +     +++   K  HLL+L+R T L  TS S+K                      +K      + + L+  GI FR                    L +PQ++ D      F+N +A+E    F+ D    +T+YI F+  L+++ +DV  LR  KLI++N  G++ EV++ F  I  D+V   D  Y  +V   + ++   W N + A F H HF SPWT ++           ++Q+  ++L Y N+K
Sbjct:   61 KAYKPKVVSIGPYHYGEK-HLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMVFLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNPIDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKK--NKLQIPQLRFDGFISSFFLNCVAFEQ---FYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDK 462          

Query:  241 KYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDAD---LLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLE-FIYKYDELENFQ------------IKRDXXXXXXXXXXXXXXXXXIHKKLKKSID-----DFVWRNSLAQN----QQNPEAKPTHLLELLRTTML-GTSPSEKTKG-------------------TKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDHPDDVKHLRK-KLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYY--SVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNNK 1323
            K Y+P V ++GP+H+  K   +  ++ K +L   F+ ++K+ D +   L+K V D  +++RK Y EE    ++   L +M+ +DGC  L  F+     +E  +            I+ D                 +  K+  S D        ++N + +     +++   K  HLL+L+R T L  TS S+K                      +K      + + L+  GI FR                    L +PQ++ D      F+N +A+E    F+ D    +T+YI F+  L+++ +DV  LR  KLI++N  G++ EV++ F  I  D+V   D  Y  +V   + ++   W N + A F H HF SPWT ++           ++Q+  ++L Y N+K
Sbjct:   61 KAYKPKVVSIGPYHYGEK-HLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMVFLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNPIDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKK--NKLQIPQLRFDGFISSFFLNCVAFEQ---FYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDK 462          

Query:  646 NSLAQNQQ-NPEAK--PTHLLELLRTTMLGTSPSEKTKGTKLPHSFRN--------------VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLV-PNDDIYYS-VKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            NSLA+++  +P A     H L++ R ++L +SP  + + T+   S RN              V EL+ AGI FR                 +G L +P++ + D T+  F+NLIA+E C  D  ND  +TSYI F+D+LID  +DV +L    I++++LG+D EVA LFN +  ++V   +D Y S +  ++ ++Y +  N   A   H++F++PW +V+F            Q+ Y+V  Y+
Sbjct:  292 NSLARDKSFDPFADMGELHCLDVFRRSLLRSSPKPEPRLTRKRWS-RNTRVADKRRQQLIHCVTELKEAGIKFRRRKTDRFWDMQFK----NGYLEIPRLLIHDGTKSLFLNLIAFEQCHIDSSND--ITSYIIFMDNLIDSHEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDTEDSYLSRLSIEVNRYYDHKWNAWRATLKHKYFNNPWAIVSFCAAVILLVLTFSQSFYAVYAYY 527          

Query:  691 HLLELLRTTMLGTSPSEKTKGTKLPHSFRN--------------VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLV--PNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            H L++ R ++L +SP+  T+   L    RN              V EL+ AG+ FR                 +G L +P++ + D T+  F NLIA+E C    +   +TSYI F+D+LI+  +DV +L    I++++LG+D EVA LFN +  ++V  P D     +   + ++Y    N + A   H++F++PW   +F          + Q+ Y+V  Y+
Sbjct:  318 HCLDVFRRSLLQSSPTPNTRSL-LKRLTRNTRVVDKRQQQLVHCVTELREAGVKFRKRKTDRFWDIEFK----NGYLEIPKLLIHDGTKSLFSNLIAFEQC-HIESSNHITSYIIFMDNLINSSEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDPKDSHLSRLSGDVNRYYNRKWNVLKATLTHKYFNNPWAYFSFSAAVILLLLTLCQSFYAVYAYY 535          

Query:  133 ERLNKLREEAPPI---QAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEA---------------------------KPTHLLELLRTTM-----LGTSPSEKTKGTKLP-HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYY--SVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            ER++K  +E P +    A K    I RVP  +       + YEP V ++GP+H  +       E     L     +       D +K V++     R+CY E    D E+     M+ +DGC  LE   K + L  F+                     +  ++   + + ++  +   N+    A                           +  HLL+LLR++      L T P+      K+P H   ++ +L+ AGI  R                 HG + +P I VDD       N +AYE C         T+Y   LD L +   DV++L  + I++N+ G D E+A+  N +G D+  +    Y   + +++ ++Y +  +   A F   +F+SPW+ V+           ++QT+Y+V
Sbjct:   23 ERMHKKLKEPPRLLSSAAGKPTCSIFRVPQSMIDCN--GRCYEPRVVSIGPYHRGQTQLKMIEEHKWRYLNVLLTRTQNLTLEDYMKSVKNVEEVARECYSETIHMDSEE--FNEMMVLDGCFLLELFRKVNNLVPFEPNDPLVAMAWVLPFFYRDFLCLENQIPFFVLETLFNLTRGDNENETNASLQSLAFAFFNNMMHRTEEDLARFKELRAKHLLDLLRSSFIPESELHTPPATNPGKEKMPSHIIHSISKLRRAGIKLRELKDAESFLVVRFR---HGTIEMPAITVDDFMSSFLENCVAYEQC-HVACSMHFTTYATLLDCLTNTYKDVEYLCDQNIIENYFGTDTELAKFVNSLGRDVAFDITQCYLKDLFEEVNEYYKSSWHVEWATFKFTYFNSPWSFVSALAALVLLVLSVIQTIYTV 442          

Query:  691 HLLELLRTTMLGTSPSEKTKGTKLPHSFRN-------------VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLV--PNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHN 1317
            H L++ R  +L    + + + +++  S+R              V EL+ AGI FR                 +G L +P++ + D T+  F NLIA+E C  D  ND  +TSYI F+D+LID  +DV++L    I++++LGND EVA LFN +  ++   P +     + ++++++Y    N + A   H++F++PW   +F          + Q+ ++   Y N
Sbjct:  343 HCLDVFRRNLLRPCSNPEPRLSRMRWSWRTRVADKRQQQLIHCVTELREAGIKFRTRKTDRFWDIRFK----NGYLEIPKLLIHDGTKSLFSNLIAFEQCHIDSSND--ITSYIIFMDNLIDSSEDVRYLHYCGIIEHWLGNDYEVADLFNRLCQEVAFDPQNSYLSQLSNKVDRNYSRKWNVLKAILKHKYFNNPWAYFSFFAALVLLVLTLFQSFFTAYPYFN 561          

Query:  241 KYYEPIVAALGPFHHTR---KPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY------KYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQ----------QNPEA--------KPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRN---------VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYE-MCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVK--DQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGY 1311
            K YEP + ++GP+HH +   K   +H  +  LK     +++      +L+K V      +R  Y E+   D E+  L  M+ +DGC  L   +      +Y  L++   +                    +  L+   +          N+          Q PE         +  HLL+L+R T +      + K      SF +          ++L   GI F+P                +G+L++P + +DD T   F+N +A+E +  D  N   +TSY+ F+  LI+   D   L ++ IL+N+ G ++EV++ +  IG D+  + +  Y  K  + + ++     +   A+F H HF SPWT  +            +Q  ++   Y
Sbjct:   46 KAYEPKIVSIGPYHHGKEHLKMTQQHKRRF-LKFFVAKMEEKGFVPQELVKAVSSLEGVIRGSYSEDLGLDSEN--LVQMMVLDGCFILTLFFVVSGKVEYTNLDDPIFRMPWILPSIRADLLLLENQVPYVLLQTLFETSKLVTCSGLNEIAFEFFNYSLQKPETFWEKHYGLEAKHLLDLIRKTFVPVPSQRRIKDHSSKSSFNDHEYLGFVLSAKKLHLRGIKFKPRKNTDSILDISYS---NGVLHIPPVVMDDFTASIFLNCVAFEQLYADSSNH--ITSYVAFMACLINEESDASFLSERRILENYFGTEDEVSRFYKRIGKDIALDLEKSYLAKVFEGVNEYTSQGFHVHCAEFIHTHFDSPWTFASSFAALLLLLFAALQVFFAAYSY 433          

Query:  694 LLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLV--PNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            L++   TT  GT   + +   K       V EL+ AG++F                  +G L +P++ + D T+  F NLIA+E C    ++  +TSYI F+D+LI+   DV +L    I++++LG+D EVA LFN +  +++  P D     +  ++ ++Y    N + A    ++F++PW   +F            Q+ ++V  Y+
Sbjct:  302 LIQSSETTNQGTPYEDMSMVEKQQQLIHCVTELRGAGVNFMRKETGQLWDIEFK----NGYLKIPKLLIHDGTKSLFSNLIAFEQCHTQSSN-NITSYIIFMDNLINSSQDVSYLHHDGIIEHWLGSDSEVADLFNRLCKEVIFDPKDGYLSQLSREVNRYYSRKWNSLKATLRQKYFNNPWAYFSFSAAVILLFLTFFQSFFAVYAYY 505          

Query:  781 VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFN----EIGTDLVPNDDIYYS-VKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGY 1311
            V EL+ AGI F+                 +G L +P++ + D T+  F NLIAYE C  D  ND  +TSYI F+D+LID  +D+++L    I++++LGND EVA +FN    E+  DL   ++ Y S + ++++++Y    N + A   H++FS+PW   +F          + Q+ ++   Y
Sbjct:  361 VTELREAGIKFKRRKSDRFWDIQFK----NGCLEIPKLLIHDGTKSLFSNLIAYEQCHIDSTND--ITSYIIFMDNLIDSAEDIRYLHYYDIIEHWLGNDSEVADVFNRLCQEVAFDL---ENTYLSELSNKVDRYYNRKWNVLKATLKHKYFSNPWAYFSFFAAVILLLLTLFQSFFTSYPY 534          

Query:  151 REEAPPIQAEKVKPKIQRVPFMLRQDTKFDK-YYEPIVAALGPFHHTRKPKYEHAEKIKLK--LAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQ------------IKRDXXXXXXXXXXXXXXXXXIHK----KLKKSIDDFV--------------------------WRNSLAQNQQNPEA--------KPTHLLELLRTTMLGTSPSEKT---KGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVL--GYHNNK 1323
            R+    +  E+      RVP + R++   ++  Y P+V ++GP+HH   P +E AE   LK  +   F  +S +    L  KVE+     +KCYDE +TKD  D+    M+ +DGC  L+FI+ +  L +FQ            +KRD                   +    + KK ++DF+                          WR +   N Q  E         +P HLL+      +G S  ++    KG     S+R+V EL++ GIHF P                 G + LP+I +DDST+   +NL+A+E CP     FGVTSY+ F+DSLIDHP+DVK LRKK IL N LG+D+EVA LFNEI + +V + + Y +VK  IEKH  N   +  A++ ++HFSSPWT +AF           +QT Y  L  G H NK
Sbjct:   27 RQHTIQVGQEESSKICHRVPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVQQFANESGKTREVLYSKVEELAVSAKKCYDERSTKDLGDKAFTEMMLLDGCFILQFIFCF--LHDFQNLKLSNRVLAYFVKRDLFLLENQIPYEVLKSLMSLRFGDAEGKKLMEDFMDDVRGLPRDKSRDKENGKGLDCRFWSWRPAPKMNNQPGEIPQVPGEIPQPVHLLDFFHNRFMGGSRGQENLSLKGDGQWSSYRSVMELKSVGIHFMPSKTDMYTDILYKSTMRGGTVTLPRIVIDDSTKSLLLNLMAHEACPGPAEGFGVTSYVYFMDSLIDHPEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWAAEWLNDHFSSPWTFLAFFGAIFALVLTFIQT-YKTLYPGNHLNK 472          

Query:  178 EKVKPKIQRVPFMLRQDTKFDK-YYEPIVAALGPFHHTRKPKYEHAEKIKLK--LAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKY----------DELENFQIKRDXXXXXXXXXXXXXXXXXI--------HKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKT--KGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVL--GYHNNK 1323
            E+   K  RVP + R++   ++  Y P+V ++GP+HH   P +E AE   LK  +   F  +S +   DL + V +  +  RKCYDE +TK+  D     M+ +DGC  L+FI+ +          + +  + +KRD                           + ++  +D+                +P HLL+      +G    E    KG     S+R+V EL++ GIH  P                 G + LP+I +DD T+   +NL+A+E CP     F VTSY+CFLDSLIDH +DVK LRKK IL N LG+D+EVA LFNEI + +V + + Y +VK  IEKH  N   + +A++ ++HFSSPWT +AF           +QT Y  L  G H NK
Sbjct:   13 EECSKKCHRVPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVEQFANNSGKTREDLYRNVAELASSARKCYDEGSTKNVGDNAFTKMMLLDGCFILQFIFCFLHDSQKLKLSNRVLAYFVKRDLFLLENQIPYKVLTSLMSLGFDGNKGQELMENFMDEVRGLPRGKSGDMENNNQPAHLLDFYHNRFMGKRGQENPSRKGDSQWSSYRSVMELKSVGIHLMPSKTDMYTDLRYKSTMRGGTVTLPRIVIDDCTKSLLLNLMAHEACPGSAEGFWVTSYVCFLDSLIDHSEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWVAEWLNDHFSSPWTFLAFFGAIFALVLTFIQT-YKTLYPGNHLNK 418          

Query:  157 EAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCY--DEEATKDYEDEFLAWMLFVDGCSTLEFIY----KYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLK----------KSIDDFV--------------------WRNSLAQNQQNPEAKPT---------HLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNN 1320
            E     +++  P+I RVP +        K YEP V ++GP++H +  + +  EK K  +   FV+ SK+   D+ + V D   + R+ Y  DE    D   EF   M+F+DGC  ++F+Y     ++ L+                        +   +K          K I DF+                    +R ++ +   N  AK           HLLEL     +  + S  +  T L + +    EL+  GIHF+P                 G L +P + +D+ST+   +NL+AYE C   +    VTSYICF+DSLIDHP+DV+ LR + IL   LG++EEVA+LFNE+   LVPN   +  VK+ IE H+ N   R +A+    +FSSPW+ +             +Q+ +++   +NN
Sbjct:    4 ERTEAMSQQQGPRIPRVPQIFSGIGSNKKCYEPKVVSIGPYYHGKLDRLQEMEKSKCNMVRGFVQQSKKLIEDVYQTVVDVAEDARRYYVEDESVKLDDMTEFTR-MMFLDGCFVIQFMYCLLRDHENLKMSSHAAALVTRDLLLLENQLPFLVLRSLMKLRFGSDEEGMKLIKDFIKHIRAMPRQRESCWKKISKFFRKTIPRRALNYSAKDPAMGEYYGAGHLLELFHMHFVDKNFSVDSSKTSL-YRYHPAMELRTVGIHFKPSKARQFTDVQFKPTWLAGRLKIPPLTIDESTKSMLLNLVAYEACLGDNKKLWVTSYICFMDSLIDHPEDVRVLRSQGILLVTLGSEEEVARLFNEVAKYLVPNPHAFNKVKNDIESHFRNTIKRWVAEHVDTYFSSPWSFITLVAASLTIALTAIQSYFTLFPLNNN 434          

Query:  190 PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHT-RKPKYEHAEKIKLKLAANFVKDSKQNDADLL-KKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY-----KYD--ELENFQIKRDXXXXXXXXXXXXXXXXXIHKK------LKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYS-VKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNN 1320
            P I +VP  L+ + K  + Y+P V ++GP+H+  R+ K    EK+K+++A  FV DSK  D ++L  +V       ++ Y+  +   ++DE    M+F+DGC  L+FI      K D  + +   +K+D                   K        + +I+DF+    L   QQ+ + +P  +L  L    L        +G  L +S    ++LQ  GIHF+P                +  L +P I ++ +TR   +NL+AYE    F +D  VTSYICF+DSLID  +DVK LR K IL N+LG D++VA LFN+IG  L PN +I Y+ VK +I     +   + +A++   +FSSPW  +AF            QT Y+V  Y ++
Sbjct:   70 PMIPKVPDKLKHENK--ECYKPSVVSIGPYHYKDRQNKLHEVEKLKVQMAREFVLDSKIKDIEILYSEVAKVAENAKRFYEGSSISCFDDEQFTRMMFLDGCFILQFIRGVMDNKLDMSDQQIILVKQDLLLLENQLPFSVLKSLMSLKNDGDDRGKEININDFLLLQIL---QQSDQRRPVWVLSWLVKGNLFPKSKLGKRGHNLYYS---AKDLQKVGIHFKPSKTSTLMDVKFVSSIFYATLKIPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLIDDAEDVKVLRSKGILTNYLGPDQKVADLFNQIGRSLEPNTNIVYNDVKRKINVSCDSTWKKWIAEWLQTYFSSPWAFIAFVAAAAVLVLTATQTYYTVYPYKSS 453          

Query:  190 PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLE---FIYKYDE------------------LEN---FQI-----------------KRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQ--NQQNPEAKPTHLLELLRTTMLGTSP-SEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNN 1320
            P+I +VP +LRQ     K Y+P + ++GP+HH  KP+    EK+K+   + FV DS     D   KV +   + R+CY E++T +++DE    ++F+DGC  L+   F+ +  E                  LEN   FQ+                  +                  I + +KK     +W+       N++  + +P HLL LL T  +     S  +  +   +S+R+ ++L+  GI FRP                   L LP + +++S +   +NLIAYE C D   +  VTSY CFLDSLI   +DVK L+ + +L  F+  ++EVA LFN++  +LVPN   Y  VK QIE    +   + +A++ H++FSSPW+ +A           ++Q+  ++   +NN
Sbjct:   44 PQIPKVPRLLRQIQSNQKCYDPSLVSIGPYHHG-KPELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEKFTQIMFLDGCFILQFIFFLLRRPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGEGGGRNKLINDFIRHIRALPPRKESIKEMIKKFAGKCIWKQPKKTWGNKETEDHQPVHLLGLLHTDHINKEACSHCSTRSSDWYSYRSAKDLRTVGIRFRPNWTNAYSDVEFKSSFRGSRLILPPVTIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVLNIFV-REQEVADLFNQMSRNLVPNPYAYSDVKRQIELDRKSIIKKWVAEWLHDYFSSPWSFIALVAATFTIVLTVIQSYVAIFPLNNN 462          

Query:  193 KIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQ------IKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHY 1173
            ++ RVP   R+  +    YEP+V ++GP+HH +K + +  EK+K ++A  FVKDS+    ++  KV++ +++ RKCY EE+T+ + DE    M+F+DG   L+ + +  + +N +      ++RD                    ++ KS  D +     A   ++   +  ++ E L     G    E T   +    + +V+EL+  GI F P                 G L +P + +++ T+P  +NL AYE C  ++ D   TSY+CF+ SLID P+DVK LR K IL+  +G+D+ +AQ+F EI T+L PN   Y  VK  +E HY
Sbjct:   16 EVPRVPSEFRKMKENTDCYEPLVVSIGPYHHGKK-ELKEMEKLKAEMAGQFVKDSRVTAEEMYSKVKELVSDARKCYAEESTRQFNDEKFTQMMFLDGYFILQVVSENLKQQNLRKEEVASVRRDLFLLENQLPFRVLIPLM---RIYKSKADHI-----AGEDKSSSRQFVYVGEELERERGGRRYGEITSWNR----YYSVEELKNVGISFMPSNTRVFTDVKFKNTLLGGALCIPPLSIEEETKPLLLNLAAYETCAGWYYDMYCTSYVCFMRSLIDKPEDVKELRSKGILRTTIGSDDRIAQIFKEITTNLAPNPTAYTKVKRSVESHY 335          

Query:  190 PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLE---FIYKYDE------------------LEN---FQIKRDXXXXXXXXXXXXXXXXXIH-----------------KKLKKSIDDFVWRNSLAQ--NQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLP-HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNN 1320
            P+I +VP +LRQ     K Y+P + ++GP+HH  KP+    EK+K+   + FV DS     D   KV +   + R+CY E++T +++DE    ++F+DGC  L+   F+ +  E                  LEN   FQ+                    I+                 + +KK     +W+       N++  E +P HLL LL T  +               +S+R+ ++L+  GI FRP                   L LP I +++S +   +NLIAYE C D   +  VTSY CFLDSLI   +DVK L+ + +L  F+  ++EVA LFN++  +LVPN   Y  VK +IE    +   + +A++ H +FSSPW+ +A            +Q+ +++   +NN
Sbjct:    4 PQIPKVPRLLRQIQSNQKCYDPSLVSIGPYHHG-KPELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEKFTQIMFLDGCFILQFIFFLLRRPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGEEGGGNKLINDFIRHIRALPPQQESFKEMIKKFAGKCIWKQPQKTWGNKETEEHQPVHLLGLLHTDHINKEACSHCSTRSCDWYSYRSSKDLRKVGIRFRPNWTNAYSDVEFKSSVRGSRLILPPITIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVLNIFV-REQEVADLFNQMSRNLVPNPYAYSDVKRRIELDRKSIIKKWVAEWMHTYFSSPWSFIALVAATFTIVLTGIQSYFAIFPLNNN 422          

Query:  190 PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDS---------KQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY---KYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPT-------HLLELLRTTMLGTS--PSEKTKGTKLPHSFRNV--------QELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSS 1227
            PK  +VP  +RQ  + ++ Y+P + ++GP+H+  K + +  +K+K+  A  FVKD          K+   ++ ++VE   + +RK Y E  +   ++E  A M+F DGC  L+F++   K  E    ++K                   +  ++   +     R  L+ N +  E++ T       HLLEL   T +G+   P   T+ +      R          +EL+  GIHF+P                 G LY+P + +DDST+P  +NL+AYE      +D+ VTSY+CF+DSLID+P+DV  LR K IL + LGND++VA+LFN+I   LVPN   Y  VK  IE HY N   R +  +    +SS
Sbjct:   64 PKFPKVPSTIRQIKQNEECYDPSLVSIGPYHNG-KDELKEMQKLKVSFARQFVKDCVNDVNQERYKEKYQEMYRRVEQVASRVRKYYIENESSQLKNEEFAQMMFFDGCFILQFLFCLLKQPE----KLKMSSHDVVLVARDLFLLENQLPFEVLNELTRL--RILLSTNPKGQESEMTAPRKPAAHLLELFHLTFVGSKDVPDASTRKSWYRDESRKTWSGRYFPAKELRNVGIHFKPSKTSLFTDVEFRRTVLAGRLYIPPLSIDDSTKPLLLNLVAYEAFLGAPHDW-VTSYVCFMDSLIDNPEDVNELRTKGILFSTLGNDKQVAELFNQISDYLVPNPYAYVEVKSAIESHYRNGFKRWILHYKGPIYSS 430          

Query:  190 PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDS---------KQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY---KYDE------------------LEN---FQIKRDXXXXXXXXXXXXXXXXXI-------------HKKLKK---SIDDFVWRNSLAQNQQNPEAKPT-------HLLELLRTTMLGTS--PSEKTKGTKLPHSFRN--------VQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSS 1227
            PK  +VP  +RQ  + ++ Y+P + ++GP+H+  K + +  +K+K+  A  FVKD          K+   ++ ++VE   + +RK Y E  +   ++E  A M+F DGC  L+F++   K  E                  LEN   F++  +                                +K KK   +I     R  L+ N +  E++ T       HLLEL   T +G+   P   T+ +      R          +EL+  GIHF+P                 G LY+P + +DDST+P  +NL+AYE      +D+ VTSY+CF+DSLID+P+DV  LR K IL + LGND++VA+LFN+I   LVPN   Y  VK  IE HY N   R +  +    +SS
Sbjct:   64 PKFPKVPSTIRQIKQNEECYDPSLVSIGPYHNG-KDELKEMQKLKVSFARQFVKDCVNDVNQERYKEKYQEMYRRVEQVASRVRKYYIENESSQLKNEEFAQMMFFDGCFILQFLFCLLKQPEKLKMSSHDVVLVARDLFLLENQLPFEVLNELTRLRFGGENMELFEAFFKHIRSMPTQRESCREKTKKKLLTISKLFRRILLSTNPKGQESEMTAPRKPAAHLLELFHLTFVGSKDVPDASTRKSWYRDESRKTWSGRYFPAKELRNVGIHFKPSKTSLFTDVEFRRTVLAGRLYIPPLSIDDSTKPLLLNLVAYEAFLGAPHDW-VTSYVCFMDSLIDNPEDVNELRTKGILFSTLGNDKQVAELFNQISDYLVPNPYAYVEVKSAIESHYRNGFKRWILHYKGPIYSS 473          

Query:  190 PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHT-RKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLK--------------KSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            P I +VP  L+ D    KYY+P V ++GP+H+  R+ K   AEK+K+++A  FV  SK++   L  +V       ++ Y+  + + ++DE    M+F+DGC  L+FI      +N +   D                     LK              K I+DF+    L Q+        T L++     +L          T + + F    +LQ  GI+F+P                +  L LP I ++ +TR   +NL+AYE    F +D  VTSYICF+DSLI+  +DVK LR   IL N+LG D++VA LFN+IG    PN ++Y  VK +I     +   + +A+    +FSSPW  +AF            QT Y+
Sbjct:   69 PMIPKVPDNLKDDEN-KKYYKPSVVSIGPYHYKDRQNKLHEAEKLKVQMAREFVLYSKKDMEILYSEVAKVAENAKRFYEGSSIRCFDDEQFTQMMFLDGCFILQFIRCVSTTDNIKNMSDQQIFHVKQDLLLLENQLPFPVLKSLMSLTPDGKDHGMKIINDFLSLQILQQSNHQRRPVLTWLVKGYLLLLLIY--------TTVAYPFH---DLQKVGIYFKPSKTNTLMDVEFVSSIFYATLKLPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLINDAEDVKVLRSNGILINYLGPDQKVADLFNQIGHSREPNTNVYNDVKGEINLSCDSIWKKWIAECLQTYFSSPWAFIAFVAAATGLVLTATQTYYT 440          

Query:    1 MAQKDENV---------RQVNKXXXXXXXXXXXXXPAEI-------EVSITIHEEA--STREERLNKLREE-APPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQ--NDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPT------HLLELLRTTMLGTSPSEKTKG------------------TKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXX-CHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            M+QKDENV          +V K             PAEI       E  ITIHEE   ++R E+L K+R   A   Q +   PKIQRVPFMLR     DKYYEP V ALGP HH  K KY+ AEK+KL+L  +F+KDS+Q  ND  LLK VED I ELR+CYD EATKD++DE LAWMLFVDGCSTLEF+ KY ELE F+IKRD          X      +  +L   + + +  +S   N++ P +  T      H+L+L    M+G  PS+ TK                   + L HSFRNVQELQAAGIHFRP                C G LYLP IKVDDS  PKFMN+IAYEMCPDF NDF VTSYI FLDSLIDH DDVKHLRKK I+QN LG+D+EVA+LFNEI TDLVPN  IY  V  QIE HY       MAQFFH+HF+SPWT + F           +QT Y+
Sbjct:    1 MSQKDENVVSMKKELSXTKVAKRGGGQASGGDQGQPAEITTTEQTSEEXITIHEEVIRTSRGEKLKKMRXALAEAAQKQNAXPKIQRVPFMLRDHKNLDKYYEPRVVALGPRHHG-KEKYKQAEKVKLQLTEHFIKDSEQTNNDETLLKNVEDKIKELRECYDXEATKDHDDEALAWMLFVDGCSTLEFMXKYXELEXFKIKRDQVAFVEQDMFX------LENQLPYQLXELLISSS---NKRRPPSLSTEPGCTHHILDL--RPMVGPRPSQSTKPGCTHRLLDLLQTMVXPRPSXLXHSFRNVQELQAAGIHFRPSEKNSLMDIYFKPLFLCCGFLYLPIIKVDDSMGPKFMNIIAYEMCPDFQNDFVVTSYIGFLDSLIDHADDVKHLRKKGIVQNLLGSDQEVAELFNEISTDLVPNXAIYRXVTAQIEXHYKTKWKTWMAQFFHDHFNSPWTFLGFIGVLLGLGLSGMQTWYA 467          

Query:    1 MAQKDENV---------RQVNKXXXXXXXXXXXXXPAEI-------EVSITIHEEASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRD------------XXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTK----GTKLPHSFRNVQELQAAGIHFR-PXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            M++KDENV          +V K             PAEI       EV ITIHEEA  R  R  KL+                          KF K+ + + + +    + R   +     I  K + +       N   LLKKV D IN+LR+CYDE+ATKDY+DE LAWMLFVDGCSTLEF+YKY++LE F+IKRD                             IH++L  SI+ F+  +  A      + +PTHLL+LLRT M+G  PS  TK     T+  HSFRNVQELQAAGIHFR                 C G LYLP IKVDDS RPKFMN+IAYEMC DF NDF VTSYI FLDSLIDHPDDVKHLRKK I++N LG+DEEVAQLFNEI TDLVPND IY +VK QIE HY       MAQFFH+HF+SPWT +AF           +QT Y+V
Sbjct:    1 MSEKDENVVCMKKELSVTKVTKSGGGQASGGDQGQPAEITTTEQTSEVVITIHEEA-IRTRRGEKLK--------------------------KFGKWQKQLKSKMP---NQRSKGFPSCSAIT-KFSTSASSQGLLNAETLLKKVGDKINDLRECYDEKATKDYDDEALAWMLFVDGCSTLEFMYKYEKLEEFKIKRDQVAFAEQDMLLLENQLPHRLLKWLIKKSKIHQELNTSIEGFIRMHGGAPRDPATKREPTHLLDLLRTRMVGCPPSPSTKSGRRSTEGGHSFRNVQELQAAGIHFRYSKTNSLRAISFKLRFQCCGFLYLPIIKVDDSMRPKFMNMIAYEMCSDFQNDFEVTSYIGFLDSLIDHPDDVKHLRKKGIVRNLLGSDEEVAQLFNEIATDLVPNDAIYRNVKTQIEDHYKTKWKTWMAQFFHDHFNSPWTFLAFIGVLLGLGLSGIQTWYAV 436          

Query:  121 STREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKY--DELENFQIKRDXXXXXXXXXXXXXXXXXIH------------KKLKKSIDDFVWRNSLAQNQQNPEAK-----------------PTHLLELLRTTMLGT--SPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            S++EER  KLR+ AP        PKIQ+VPFMLR+    +KYYEP   A+GPFHH   P+ E AE+ KL L   F+K + Q    L +KVE  I ELR+CY EEAT+ Y+DE LAWMLF+DGCSTL+FI+ +  +ELE   IKRD                               + LKK+I+ +V  N  A  ++  E K                 P HLL+LLRT MLG   +P ++ K   +  SFRNVQEL AAGIHF+                  G L LP I VDDST PKFMNLIAYEMCPDF NDF VTSYI FLD+LIDH DDVK LR   +L N LG+D+EVA+LFNEIGTDLVPN DIY+ VK +IEKHY       M+QF H+HF SPWT +AF           +QT ++V
Sbjct:    7 SSKEERFEKLRK-APEAPDYSSNPKIQKVPFMLRKPKTSEKYYEPRAVAIGPFHHGN-PRCELAEEFKLMLTKRFLKYTSQTVEALHQKVEKKIKELRECYAEEATQTYDDETLAWMLFLDGCSTLQFIHSFVDEELEELSIKRDQIAFAQQDLFLLENQVPYQVLELLMSSSNKCEDLKKAIETYVQANIGAPGKKQSEKKVAITMEKEKEPAHQEKEPAHLLDLLRTRMLGPPKNPDKRAKDHSV-QSFRNVQELDAAGIHFKLSNSSLLGDISFVSHSFAGYLSLPAISVDDSTGPKFMNLIAYEMCPDFQNDFAVTSYISFLDALIDHADDVKELRSAGVLYNLLGSDKEVAKLFNEIGTDLVPNTDIYHDVKAEIEKHYKTKWKTWMSQFCHDHFRSPWTFLAFVGVLAALGLTGIQTWFAV 430          

Query:  118 ASTREERLNKLRE-------EAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDE--FLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXX---IHKKLKKSI-DDFVWRN-----SLAQNQQNPEAKP----------------------------THLLELLRTTMLGTSPS-EKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHNNK 1323
            A + E+R N+LR+        +  +   + +P IQ V   LR +   +KY+EP V A+GP HH + P++E   ++K +LAA+FV DS +++  L K+VEDNI EL++CYDE+ T+ Y+ +   LAWM FVDGCS L+FI KY  LE F+IKRD                    ++  +  SI ++ +W        +        AKP                            THLLELLRT MLG + +  +    +LP SFRN +EL AAGIHFR                  G L+LP +  D    P F+NLIAYEMCPDF ND+ VTSY+ FL S I HP+D K LR   IL N L  DE +AQLFNEIG DLV N  I + +  ++EKHY +     MAQFF +HFSSPW ++AF           +QT YS++ YH  K
Sbjct:    2 ADSLEQRFNRLRDAGTKNQDSSTSVVPSRSRPIIQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWE---ELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLCFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIH-ISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPK 444          

Query:  268 LGPFHHTRKPKYEHAEKIKLKLAANFVK-DSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKY--DELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNS-LAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVA 1245
            + PFHH   P+ E AE+ K  +   F++  S+Q   D+  K+++ + ELR CY EEATK Y++E LAWMLF+DGCS L+F++ +   +LE   I+ D                            FV  N  L +NQ      P  +LE+L   M  +   E+ K +   + + N+                             G L LP I VDDST PKFMNLI YEMCP FH DFGVTSYI FL +LIDH  DVK LR   +L N LG+D++V ++FNE+  DLVPN  IY      IE HY       +++FF+ HFSSPWT +A
Sbjct:    1 MDPFHHGN-PRCELAEEFKHMMTKIFLEYTSRQTAEDVHHKIDEKVKELRDCYAEEATKRYDEETLAWMLFIDGCSILQFMHSFVHKKLEELSIRMDQIA-------------------------FVRHNLFLLENQV-----PYKILEML---MSSSDKREELKDSIKIYVWANI-----------------------------GFLCLPPISVDDSTGPKFMNLITYEMCPGFHTDFGVTSYIKFLRALIDHASDVKKLRSVSVLYNLLGSDKKVVEIFNELRIDLVPNTRIYCDAIADIENHYETKWKTCISRFFNHHFSSPWTFLA 267          

Query:  196 IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRK-PKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEF-----------------------IYKYDEL---EN----FQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMC-PDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            I RVP  +R+  K  + Y+P V ++GPFH      +++  E +K       +  +K     L++ V D     R CY E    + ED     M+ +DGC  +E                        +Y Y +L   EN    F ++R                  +   + K   ++V  N +     +   +  H+L L+RT+++GT   E T G K+P    NV  L  AGI F+                  G   +PQ+ +D+ T P   NLIA+E C P+  +   +TSY   +D+LI+   D+  L ++ IL N+L + E+ AQ FNE+  +       Y  + + + KHY    N+ M +   EHF+SPW +++           ++QT Y++  Y+
Sbjct:   48 IFRVPLQIRR--KNAQAYKPYVISIGPFHRGGGGDQFQLLENVKRWYLQCLLSHAKTTLPGLIEGVADLEKHARDCYAEPLGLNKED--FVEMMVLDGCFLIELFRKGPSHDLPDEKDPVHCMSGIRLYLYHDLLLLENQLPWFVLERLYNLTAVKSTTSEGNASSLADLVLKFFTEYVGDNLILNPSVDLRPEILHILGLIRTSVIGTFKHEST-GNKMP-KVPNVTTLSEAGIKFKEGPRGDMLKMKFEK----GEFTMPQLVIDERTGPLLRNLIAFEQCYPNCLHT--ITSYAVLMDNLINSSKDIDLLCERKILVNWLSS-EDAAQFFNELYNETTVMGSCYGKLCEDVNKHYNTNWNKWMEKLRREHFNSPWAIISLVAAFILLVLTVLQTYYTIHPYY 439          

Query:  196 IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRK-PKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLK----------------------KSIDDFV---WRNSLAQNQ-------QNPEAKPTHLLELLRTTM------LGTSPSEK------TKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG-VTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            I RVP  +R+     + YEP + ++GPFH  R   +++  EK+K       + D+     +L+  V D     R CY E      + +F+  M+ +DGC  +E   K   +                         +  +L                        S+ D V   +R S+A +         N   +P H+L+L+RT +      LG+   E+      +K  +LP    NV  L  AGI F+                 +G+  +P +++D+ T P F NLIA+E C   H+    +TSY   +D+LID   D+  L +  IL N+L + E+ A+LFNE+  D       Y  + +++ K+Y    N+ M +   EHF +PW +++           ++QTVY++
Sbjct:   50 IFRVPHQIRRXKI--QAYEPDIVSIGPFHRGRGGDQFQLMEKVKRWYLQCLLADANITLKNLITGVVDFNKRARDCYAEPLDHFNKKDFVE-MMVIDGCFLIELFRKALSVNRQDENDPVFNVTCMLPYLYHDLLLLENQLPWFVLERLYNLTAVKNTTSEGNASSLTDLVLNFFRQSVADDDIFIFKPSPNVPPEPLHILDLIRTVIVVPFEDLGSKRKEEGEDQQQSKERELPQGVPNVTTLSEAGIKFQRSFKTPDGIMNIKFE--NGVFTIPPLEIDERTGPLFRNLIAFEQC--CHSRLHKITSYAVLMDNLIDSSKDIDLLCEMGILVNWL-SPEDAARLFNELYNDTAVIGFYYEGLCNEVNKYYKTDWNKWMEKLRREHFGTPWAIISLVAAFILLVLTMLQTVYAI 456          

Query:  247 YEPIVAALGPFHHTRK-PKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFI---YKYDE-----------------------LEN----FQIKR-----DXXXXXXXXXXXXXXXXXIHKKLKKSI-DDFVWRNSLAQNQQNPEAKPTHLLELLRTTML--------------GTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQT 1290
            YEP + ++GP H  R   K++  EK+K       + D+    A+L+  V D     R CY E      + +F+  M+ +DGC  +E     +  D+                       LEN    F ++R                X      +    K+S+ DDF+++  L     N   +P H+L+L+RT ++              G    ++++    P    N   L  AGI F+                 +G+  +P + +D++T P F NLIA+  C        VTSY   +D+LID   D+  L    IL N+L + E+ A+ FNE+  D +     Y  + +++ K+Y    N+ M +   EHF SPW +++           ++QT
Sbjct:  699 YEPDIVSIGPLHRGRGGDKFQLMEKVKRWYLQCLLADANITLANLITGVVDFKKRARDCYAEPLDHFNKKDFIE-MMIIDGCFLIELFRKGFSVDQRDENDPVFNVSCMPQYLFHDLLLLENQLPWFVLERLYNLTAVKNTTSEGNAXPPSPTLVLNFFKQSVADDFIFKPCL-----NLPHEPLHILDLIRTWIVFPCKEEGLGCKRKVGNDDQQQSEERPPPQRVPNATTLSEAGIKFQKSFKTSDCIMNINFE--NGVFTIPPLGIDETTGPLFRNLIAFXQCCH-SRPHKVTSYAVLMDNLIDSSKDIDLLCDMGILVNWL-SPEDAARFFNELYNDTMVIGFYYEGLCNEVNKYYKTDWNKWMEKLRREHFGSPWAIISLVAAFILLVLTMLQT 1087          

Query:  109 HEEASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDE--------------------------LEN---FQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSE-KTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTD-LVPNDDIYY-SVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            H+  + R +    + +E   +        I +VP  LR     +K Y P V ++GP HH +K   E  E+ K +    F+  +  +  D + K++    +LR CY     +   DEF+  ++ VD    +E + +Y                            LEN   F I  D                  +   K S   +V R+ L  +      K  H ++L+RT  L T   E + +G+    +  ++ +L  AG+ F+                  GIL +P + + DST     NL+A+E C    N      YI  +D L++ P+DV+ L K  I++N LG++ EV+ L N +G   LV  D+ YY ++   + K+Y    N+  A   H++F++PW +++           ++QTV S+
Sbjct:    9 HDFENPRIQLTTSMSQELDGLTPLSASCCIYKVPEQLRCVN--EKAYTPQVVSIGPIHHGKKG-LEDMEEHKKRYLQYFLYRTGVSLEDYVTKIKGKEEKLRSCY-AHTIELCSDEFVR-IILVDAAFIIELLLRYGGYIVHDSNDRIFNKPWLINIICPDMLLLENQLPFFIXEDLFATAEVPATVPSVFDLSYTYCKVSTSLYVKRDGLGSSSS---FKVEHFVDLVRTLNLPTDQEENENRGSVESLAVPSMTKLHQAGVKFKARSSKNLFDMCFQ----EGILEIPNLNISDSTELVLRNLVAFEQCHCTPNTRYFNDYIFLMDYLVNTPNDVELLVKNGIVENMLGDNNEVSTLINSLGKGVLVFRDEFYYATLMKDLNKYYEKPWNKWKADLKHKYFNTPWKIISVIAATFIIILTLIQTVSSI 426          

Query:  196 IQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDE--------------------------LEN---FQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFR--NVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDL-VPNDDIYY-SVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            I RVP  LR+    +K Y P V ++GP HH  K   E  E+ K +    F+  +  + A  ++K++D   ELR CY         DEF+  ++ VD    +E + +Y+                           LEN     I  D                  ++  K+S + ++ +     N + P  K  H ++L+RT  L T P E  K  +   +    ++ +L+ AG+ F+                  GIL +P++ + D+T     NLIA+E C    N F  + YI  +D+L++ P+DV+ L K  I+++ LG++ EV+ L N +G  L V  D+ YY ++  ++  +Y    N+  A    ++F+SPWT ++           ++QTV S
Sbjct:   38 IYRVPEELRRVN--EKAYTPQVVSIGPLHHG-KEGLEDMEEHKKRYLKYFLDRTGVSLAGCVQKIKDKEAELRGCYAHTIGL-CSDEFVR-IILVDAVFIIELLLRYEGYVVRDSNDRIFNKPWLLKFIVPDMLLLENQLPLFILEDLFATAEVPASVPSVLDLFYEFCKESTNFYMEKG----NWERPSFKVEHFVDLVRTLHLPT-PEENLKNGESVETLAVPSMTKLRQAGVKFKARSGKNLFDICFKD----GILEIPKLYIYDNTELVLRNLIAFEQCHCTRNTFYFSDYIILMDNLVNTPNDVELLVKNGIVEHLLGDNNEVSTLINSLGKGLFVFRDEFYYATLLKELNIYYEKPWNKWKADLKQKYFNSPWTTISVIAATFIIILTLIQTVCS 424          

Query:  247 YEPIVAALGPFHHTRKP-KYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEF-----------------------IYKYDEL---EN----FQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYH 1314
            Y+P + ++GPFH  R   ++   E +K   +   +  +    A L+K V D     R CY E +    +++F+  M+ +DGC  +E                        +Y Y +L   EN    F ++R                  +   +       V  N +     NP     H+L+L+R+ ++     E+ +G ++     NV  L  AGI F                   G+  +P + +D+ T P F NLIA+E C     +  +T Y   +D+LI+   D++ L +K IL+N+L + E+ AQ FNE+  +       Y  + +++ +HY    N+ M +   EHF SPW +++           ++QTVY++  Y+
Sbjct:   26 YKPDIVSIGPFHRGRHSNQFRLMENVKRWYSHCLLSHANITLATLIKGVVDLDKRTRDCYAEPSDHLNKNDFVE-MMVLDGCFLIELFRRGPSVDHQDQNDPVYNMSGMRLYLYHDLLLLENQLPWFVLERLYNLTAVKNTTCKENAPSLTHLVLNFFRHSVGDNGILNTSVNPPPTILHILDLIRSVIVDQF-EERNEGKEMQR-VPNVTTLSEAGIEFEKSSPVGVLNIKFDK----GVFTMPPLVIDERTGPLFRNLIAFEQCYR-RCEHLITCYAVLMDNLINSSKDIELLCEKGILENWL-SPEDAAQFFNELYNETTVIGSYYGGLCEKVNQHYHTDWNKWMEKLRREHFDSPWAIISLVAAFILLVLTVLQTVYTIHQYY 403          

Query:   94 VSITIHEEAST-REERLNKLR---EEAPPIQAEKVK-PKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYD---ELENFQIKRDXXXXXXXXXXXXXXXXXIH----------KKLKKSIDDFVWRNSLAQN-----QQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLP--HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLGYHN 1317
            + I + + AS+ RE+R   +    E++   Q  + K  +I +VP MLR    F   +EP V ++GP+HH  K     AE +K  +   F+ +S+Q    L  K+   I+ELR CY++ ATK Y DE LAWM+ VDGCS L FI  Y    +L++  IK                               ++  + I+ F+   S A+      + + E KP HLL+LLR  +LG   + +T+  K    +SFRNV EL+AAGI F+P                 G L LP+I +DDST+ +F+NLIAYEMCP+  N+  VTSYICFLDSLID P+DVK LR++ +L+NFLG+D+EVA+LFNEI TDLVP+ D Y  VK +I+KHY    +  +A+  H HFSSPWTV+AF           +QT Y+V   HN
Sbjct:   47 IDIVVEDNASSSREKRFKSVMGGPEDSKRSQLSETKWARIPKVPHMLRGTKDFKILFEPRVVSVGPYHH-HKHDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDEDLAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGFEEGMQMIEQFI--GSAAETDPPAVKSDNEEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILLGFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRHN 476          

Query:   79 PAEIEVSITIHEEASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY---KYDELENFQI---KRDXXXXXXXXXXXXXXXXXIHKK------LKKSIDDFVWRNSLAQ-NQQNPEAKPTHLLELLRTTMLGTS-------------PSEKTK---------GTKLP-----------HSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSVLG 1308
            P   E  I I+E +   +  +  LR+     +++   P+  +VP MLR    F K YEP V ++GP+HH  KP     E IK   A  F+ DS Q+   L  K+  NI  +RKCYD  +T +Y+DE LAWM+ +DGC  L+FI    K + L N QI    +D                    K      +KK I +FV +    + + +  + +P HLL LLR+++LG               P +K K         G + P           +SFR++++L+A+GIH +P                HG L LP+I +DD T+ KF+N++AYEMCPD  +D+G+TSYIC LD LIDH DDVK LR K IL N LGNDE+VAQLFNEIG DLV + + Y  VKD+I++HY    N  +AQ  H+HFS+PWT++AF           VQT Y++ G
Sbjct:   27 PEPKEHRIDINEISPRVKNWIGGLRKTEERTESQTQWPRTPKVPQMLRGTQDFKKMYEPRVISIGPYHHG-KPDLGRVEMIKPPCAQEFLADSNQDIEALYTKIRSNIETVRKCYDWSSTSEYDDEALAWMMLLDGCFLLQFIRRKGKINFLRNHQIIFVLQDLFLLENQLPYGVLKLIFEEAKFNDDSLMKKKIKEFVTKTGRPEASDEELDEEPPHLLHLLRSSLLGRDKRIRGSQPEQEQQPEKKGKSSSSQGGDWGFRCPWKKCKQRAIWLYSFRSIKDLKASGIHLKPSRTSVLTDVSFKSSFFHGYLKLPRIIIDDFTKKKFLNMVAYEMCPDAPDDYGITSYICLLDDLIDHADDVKELRSKNILYNLLGNDEDVAQLFNEIGNDLV-DPEAYEDVKDRIQEHYNKRMNTWIAQALHDHFSTPWTIIAFIAAVLILFLTGVQTYYALPG 480          

Query:   79 PAEIEVSITIHEEASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKY----DELENFQIKRDXXXXXXXXXXXXXXXXX-------------------IHKKLKKSIDDFVWRNSLAQNQQNPEA--KPTHLLELLRTTMLG----TSPSEKTKGTK----------LPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYS 1299
            P E  + + I+         + K +E  P   ++   P++ +VP MLR    F K YEP V ++GP+HH  KP     E IK   A  F+    Q+  DL  K+E  I  +RKCYD + T  Y DE L WM+ +DG   L+FI       D++ N  + RD                                    + K +K+ + DF     L+   Q  E   +P+HLLELLR+ +LG      P +K +  K          +  SFR+++EL+AAGI+ +P                +G L LP+I +D  T+ KF+N++AYEMCPD   D  VTSY+CFL  LID  DDVK LR K IL N LG+DE+VA++FNEIG DLV +   Y  VK +I+KHY    N  +A+  HEHF SPWT  +            +QT Y+
Sbjct:   29 PKEHRIDVEINPTVENWNRIVQKAKERIP---SQSQWPRLPKVPHMLRGTQDFKKLYEPRVISIGPYHHG-KPHLRPGEMIKPLYAEQFLAGINQDFKDLYTKIESKIEAVRKCYDTKPTNRYNDEALIWMMLLDGLFLLQFIGSTVDPRDDMSN--VLRDHQINFVTQDLFLLENQLPFGVLKLIFEGANFQDAPPMEKTIKEFVTDFGMPEGLSSEIQLEEENKEPSHLLELLRSALLGGYKKIQPKQKQEAEKKGKSSSSGGGIWESFRHIKELKAAGIYLKPSRKSFLTEISFKSHFFYGCLKLPRITIDGFTKTKFLNMVAYEMCPDAPVDQAVTSYVCFLYELIDQADDVKELRSKHILHNLLGSDEDVAKIFNEIGNDLV-DPGAYGDVKARIQKHYDKRVNTWIAEGLHEHFRSPWTFTSLIAAVWILIVTGLQTYYA 467          

Query:  187 KPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYE---------DEFLAWMLFVDGCSTLEFIYKYDELE----NFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDD---------FVWRNSLAQNQQNPEAKPTHLL-------------ELLRTTMLGTSPSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            +PKIQRV   LR    F+K+Y P   ++GP HH        AEK KL  AA +++++     DL KK+ DNI+EL+  +D++               +E L+WMLFVDGCS L  + K +  E    N ++ +                  + K L K  D+         F+  +  A   ++   K   ++             E  +  +   S  EK K      ++RN+Q+L+  GI+F+                    L LP+I VDDS+   F+NLIAYEMCPDFHND+G+ S+  F+DSLID+P+DVK LR K IL N LG+DEEVA+LFN I TDLVPN D Y  V+ +I  HY N  N  +AQ F  +FSSPW ++AF           +QT ++V
Sbjct:   24 RPKIQRVLKSLRNRKNFEKHYSPKCVSIGPIHH-HNTNLILAEKYKLMWAAKYIENNGYIPEDLHKKIADNIDELKGHFDDDVLTSTRWSLAGFRSLEEKLSWMLFVDGCSLLYILEKANLNEPWHMNIKVDQLVLVMMDVLLLENQLPYQVLKLLWKDEDESGLIESMMNFLDCHHWATPDESQSGKKKDMVPKRKGEGVTIRNNEANKENLSKKSRDEKVKMM----TYRNIQDLRDVGINFKSSKTRRPRDIDFSEGLFTAELTLPEIVVDDSSATTFLNLIAYEMCPDFHNDYGICSFAAFMDSLIDNPEDVKLLRSKEILLNSLGSDEEVAELFNIISTDLVPNADTYLEVRAKIHDHYRNRCNTWIAQGFRTYFSSPWAIIAFIAALIALVLTFIQTWFTV 425          

Query:  187 KPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEAT----KDYE-----DEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDXXXXXXXXXXXXXXXXX--------------IHKKLKKSIDDFVW----------------------RNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKTKGTKLPHS-----------------------FRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            +PKIQRV   LR    F+K+Y P + ++GP HH      +  EK KL  AA +++++     DL KK+ DNI+EL+  + ++      K  E     +E L+WMLFVDGCS L  + K   DE  +  IK D                               + K +   +D   W                       +S++   ++    PTHLL+L R  +L TS S KTK  +  ++                       +R++Q+L+A GI  +                    L LP+I VDD++   F+NLIAYEMCPDF ND+G+ S+  F+DSLID P+DVK LR K IL N LG+DEEVA  FN I TDLVPN  IY+ V+++I +HY N     +A  FH +FS+PW ++AF           +QT ++V
Sbjct:   24 RPKIQRVAEYLRNRKNFEKHYSPKLLSVGPIHHDNT-NLKLGEKYKLMWAAKYIENTGHIPEDLHKKIADNIDELKGHFGDDVLTLTGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDNDSELIKSMMTFLDCHHWATPDESQPDKEKDMVPKGKGEGEHSVSITNESQLETPTHLLDLQRKIILTTSNS-KTKSNEANNNKWSQKNSDENVKKNSKEDVKMMTYRSIQDLRAVGIRLKSSATRRPTDVDFSAGWFAAKLTLPEIVVDDTSAATFLNLIAYEMCPDFENDYGICSFAAFMDSLIDRPEDVKELRSKGILLNSLGSDEEVADFFNIISTDLVPNTKIYFEVREKIHEHYCNKCKTWIALGFHTYFSNPWAIIAFLAAFIALALTFIQTWFAV 463          

Query:  139 LNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKYDE-----LENFQ-------IKRDXXXXXXXXXXXXXXXXXIHKK------LKKSIDDFVWRNSLAQNQQNPEAK---PTHLLELLRTTMLGTS--------------------------PSEKTKGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMA 1200
            +  L+      Q++   P+I +VP +LR    F++ YEP V ++GP+HH  KP  +  E IKL+ A  F+ DS Q+   L  K+  NI  LRKCYD+  T   +DE LAWM+ +DGC  L+FI    +     L N         ++RD                    K      +++ I +FV R  +A  Q + E +    +HLL+LLR+ +LG S                          P +K K   +  SFRN++EL+AAGIH +P                 G L LP I VDDST+ +F+N++AYEMCPD  ND+ VTSY+ FL  LIDH DDVK LR + IL N LG+DE+VA++FNEI  D+V + ++Y  VK +I+K Y    N  +A
Sbjct:   48 IKSLKNAEESTQSQSSWPRIPKVPQLLRGTHDFERLYEPRVISIGPYHHG-KPHLQPVETIKLQYAQKFLADSDQDIEALYTKIGSNIEALRKCYDKIPT---DDEKLAWMMLLDGCFLLQFIRSRKDGSTVDLSNVLRIHQINFVERDLFLLENQLPFGVLQLIFEGAKFNDGSTMEQMIKNFVTR--IASLQPSSEIRLDERSHLLDLLRSAILGKSAPKQERQPDKKGKSSSSSGGDGRFCCPWKKGKQQGIRQSFRNIKELKAAGIHLQPSRTRFLTDISFNSYFFRGYLNLPPIIVDDSTKSRFLNIVAYEMCPDAPNDYTVTSYLRFLYELIDHADDVKELRSRHILINHLGSDEDVARIFNEIANDVV-DTEVYGDVKARIQKDYNKRVNTCIA 441          

Query:  187 KPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHH--TRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEE----ATKDYE-----DEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDXXXXXXXXXXXXXXXXXI-----------HKKLKKSIDDFVWRNSLAQNQQ----------NPEAKPTHLLELLRTTMLGT-SPSEKTKGTKLPH-SFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            + +IQRV   L+    F+K+Y P + ++GP HH  T     +  EK KL  AA +++++  N  DL KK+ DNI+EL+  + ++    A K  E     +E L+WMLFVDGCS L  + K   DE  +  IK D                               +L KS+  F+ R+  A  +           + E  PTHLL+L R  +L T S S K   + +   S+R+VQ L+A GI  +                    L LP+I VDD +    +NLIAYEMCPDF ND+G+ S+  F+DSLIDHP+DVK LR K IL N   +DEEVA LFN I T+ +P+ +IY+ V+ +I++HY N     + Q  + +FS+PW  +AF          ++QT ++V
Sbjct:   25 RTQIQRVAEYLKNRKDFEKHYSPKLVSIGPIHHGNTSNANLKLGEKYKLTWAAKYIENAGLNPCDLHKKIIDNIDELKGHFSDDVLTLAGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDNNESELIKSMKMFLTRHPWATLESILELLTIISFSWEKLPTHLLDLQRNIILFTQSKSPKNLESHVRKMSYRSVQSLRAVGIRLKSTATRNPQSIEFAEGWFTAKLTLPEIVVDDRSAATILNLIAYEMCPDFENDYGICSFATFMDSLIDHPEDVKLLRSKGILLNSPWSDEEVANLFNSIRTNFIPDTEIYFKVRAKIDEHYCNRWKTWIGQGLNTYFSNPWAFIAFVAAFIALALTLIQTWFTV 432          

Query:  178 EKVKPKIQRVPFMLRQDTKFDK-YYEPIVAALGPFHHTRKPKYEHAEKIKLK--LAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIYKY----------DELENFQIKRDXXXXXXXXXXXXXXXXXI--------HKKLKKSIDDFVWRNSLAQNQQNPEAKPTHLLELLRTTMLGTSPSEKT--KGTKLPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQT 1290
            E+   K  RVP + R++   ++  Y P+V ++GP+HH   P +E AE   LK  +   F  +S +   DL + V +  +  RKCYDE +TK+  D     M+ +DGC  L+FI+ +          + +  + +KRD                           + ++  +D+                +P HLL+      +G    E    KG     S+R+V EL++ GIH  P                 G + LP+I +DD T+   +NL+A+E CP     F VTSY+CFLDSLIDH +DVK LRKK IL N LG+D+EVA LFNEI + +V + + Y +VK  IEKH  N   + +A++ ++HFSSPWT +AF           +QT
Sbjct:   13 EECSKKCHRVPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVEQFANNSGKTREDLYRNVAELASSARKCYDEGSTKNVGDNAFTKMMLLDGCFILQFIFCFLHDSQKLKLSNRVLAYFVKRDLFLLENQIPYKVLTSLMSLGFDGNKGQELMENFMDEVRGLPRGKSGDMENNNQPAHLLDFYHNRFMGKRGQENPSRKGDSQWSSYRSVMELKSVGIHLMPSKTDMYTDLRYKSTMRGGTVTLPRIVIDDCTKSLLLNLMAHEACPGSAEGFWVTSYVCFLDSLIDHSEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWVAEWLNDHFSSPWTFLAFFGAIFALVLTFIQT 406          

Query:  121 STREERLNKLREEAPPIQA-EKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDE-------EATKDYE--DEFLAWMLFVDGCSTLEFI------------YKYDEL-----ENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVW------RNSLAQNQQNPEAKPTHLLELLRTTML--GTSPSEKTKGTK----LPHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            +T EE + +L+      Q  +  +PKIQRVP  ++  TKF ++Y P   ++GP HH      +  EK KL  AA ++K++     DL KK+ DNI+EL+  + +       E+ + Y   +E L+WMLFVDGCS L  +             K D+L     +   ++                   + K +   +D   W      R+   Q  Q+    P HLL+L R  +L   T   E  K  K    +   + N+++L+A GI  +                    L LP+I VDD++   F+NLIAYEMCP+F ND+G+ S++ F+DSLIDHP+DVK LR K IL N LG+DEEVA+LFN IGTDLVPN + Y+ VK ++  HY  +   ++  ++     + +  +A            +QTV++V
Sbjct:    5 TTLEENIVELQIYIDTNQTPQNSRPKIQRVPRYVKNRTKFKEHYSPKFVSIGPIHHGNTD-LKLGEKYKLMWAAKYIKNTGSIQKDLYKKIADNIDELKGHFSDDVLTLTGESLEGYHSLEEKLSWMLFVDGCSLLHILEKTMLYEPGHMNVKVDQLVLVMMDVLLLENQLPYQVLKLLWKDSNESELIKIMTNFLDCHHWATLDNKRSRRWQLNQDTTTIPAHLLDLQRNIILIKSTPKIENYKANKENWRMKTIYMNIKDLKALGIRLKSSKTRRPKDIDFTEGWFTAELTLPEIVVDDTSATTFLNLIAYEMCPNFDNDYGICSFVAFMDSLIDHPEDVKVLRSKGILLNSLGSDEEVAELFNIIGTDLVPNPETYFEVKAKMIDHYYKYRTGIVRGYYTYFRIAAFIAIAL---------TFIQTVFTV 427          

Query:  118 ASTREERLNKLREEAPPIQAEKVKPKIQRVPFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEAT----KDYE-----DEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDXXXXXXXXXXXXXXXXXIHKKLKKSIDDFVWRNSLA--------------------QNQQNPEAK----------------PTHLLELLRTTMLGTSPSEKT--KGTKL------PHSFRNVQELQAAGIHFRPXXXXXXXXXXXXXXXCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFXXXXXXXXXXIVQTVYSV 1302
            + T +E+  +L+ +  P   +  +PKIQRVP+  R+ +   K+Y P + ++GP HH R    +  EK KLK AA +++++  N  +L +K+ DNI+EL+  + ++      K  E     +E L+WMLFVDGCS L  + K     + +IK                   +  +L   +   +W+N+ +                    Q+  N E +                PTHLL+L    +L TS S+    K T L      P ++R +++L+A GI  +                    L +P I V++      +NLIAYEMCPDF ND G+ SY+  +DSLIDHP+DVK LR K IL   + +DEEVA LFN IGTDLV N   Y+ V+ ++  HY N     +A  F  +F++PWTV+AF           +QT ++V
Sbjct:    3 SQTLKEKFVELQSKQTP---QNSRPKIQRVPYYRRRMSNLGKHYTPKLLSIGPIHHDRSD-LKLGEKYKLKWAAEYIENTALNPEELHQKIADNIDELKGRFSDDVLTLTGKSLEGFHSLEEKLSWMLFVDGCSLLYLLEK----GHMKIK------VGQLVLVMMDVLLLENQLPYEVLKLLWKNNESELIKCMMSFPNYLRNIPGESQSDNNMEGEGEHSVSIITNESQSETPTHLLDLQHKVILTTSKSKGKILKWTSLKKNEFKPITYRGIEDLRAVGIRLKTSATRRPTDVDFTAGWFTAKLTIPVIYVNNLAASNLLNLIAYEMCPDFDNDCGICSYVALMDSLIDHPEDVKVLRSKGILCT-VWSDEEVASLFNIIGTDLVINIFNYFEVQVKLSDHYFNKYKSWIALGFRTYFNNPWTVIAFLAAFTALALTFIQTWFTV 435