ppa024340m, ppa024340m (mRNA) Prunus persica

Query:  490 KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGA---YVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            K  Y  +L+AC   ++L   ++IHQH       +D  V   L  LY  C  +  A+ +F  +    V+ WN +I  ++ +G +D  I +   M   G  PN  T   VL   +   A+  G  +H  +    L  +V + T L+D Y+KC  +  A+R+F ++  ++ V W+AMI     Y +CD   +A+ L  +M   + I P   T+  +L  C  L                              +YA+        + FD M  ++ VS+SA+I G V +   KEAL IF  MQLSG DPDL TM+GVLPACSHLAALQHG C H Y IV GF TDT ICN LIDMYSKCGKI+  R+VF+RM   DI+SWNAMI+GYGIHGLGM A+  FH +LA G+KPDD+TFI LLS+CSHSGLV EG+ WF+AMS DF+I PRMEH ICMVD+LGRAG + EAH FI+ MPFE DVR+WSALL+ACR+H NIELGEEVSKKIQ  G E TGN VLLSNIYSA GRWDDAA++RI QK  GLKK PGCSW+EINGI+H FVGGDQSH Q +QI+ KLEELLV+MKRLGY AE SFV QDVEEEEKE+ILLYHSEKLAIA+ IL+L+ G+PILVTKNLRVCGDCH AIK +TLITKREI VRD  RFHHFK+G CNC DFW
Sbjct:    8 KNNYLHLLEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCD---DAVQLIMQMQ-EEGICPNSSTIVGVLPTCQCL------------------------------LYAR--------KIFDVMGVRNEVSWSAMIGGYVASDCMKEALDIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHGFCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMDRHDIVSWNAMIIGYGIHGLGMEALGLFHDLLALGLKPDDITFICLLSSCSHSGLVMEGRLWFDAMSRDFSIVPRMEHCICMVDILGRAGLIDEAHHFIRNMPFEPDVRIWSALLSACRIHKNIELGEEVSKKIQSLGPESTGNFVLLSNIYSAAGRWDDAAHIRITQKDWGLKKIPGCSWIEINGIVHAFVGGDQSHLQLSQINRKLEELLVEMKRLGYQAECSFVFQDVEEEEKEQILLYHSEKLAIAFGILNLKAGRPILVTKNLRVCGDCHTAIKFMTLITKREITVRDANRFHHFKNGTCNCGDFW 645          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHG-----ACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRM-VTRDIISWNAMIVGYGIH 1641
            CI+SKSL +AKKIHQH LKNT+     S +L K+  LY++CNQV LA R+FDEIP PSVILWN +IRAYAWNGPF+ AI LY+ +L  GV+P KYTYPFVLKACSGL A+E G EIH HAK  GL SDV+VCTAL+D YAKCG L EAQ +F  M ++DVVAWNAMIAG SL+GL DD +Q+++QMQ+ G  PN+STIV VLPT                                      CQC+ YAR+IFD + V+NEV WSAMIG YV  D M+EA+ +F  M L   I+P   T+  +L AC+ L  L  G   H Y I  GF  +T++ N ++ MY+KCG I  A   F++M+  D VS++A+I G   +G   EAL +FH +   G  PD  T + +L +CSH   +  G     A    +SIV         C  ++D+  + G I+        M    D+  W+A++    IH
Sbjct:   18 CIQSKSLTEAKKIHQHFLKNTSNAD--SSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPT--------------------------------------CQCLLYARKIFDVMGVRNEVSWSAMIGGYVASDCMKEALDIFRMMQL-SGIDPDLTTMLGVLPACSHLAALQHGFCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMDRHDIVSWNAMIIGYGIHGLGMEALGLFHDLLALGLKPDDITFICLLSSCSHSGLVMEGRLWFDAMSRDFSIV----PRMEHCICMVDILGRAGLIDEAHHFIRNMPFEPDVRIWSALLSACRIH 455          

Query:  190 YHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQP-SVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALG-LASDVYVCTALIDLYAK-CGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQC---IAYARRIFDAIDVKNEVCWSAMIGAYVI---CDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y I   +CIR ++    K +H+ L+++   L   S +L  +  LY  C   + A  +F+ +     ++ W+ ++  +A N    +AI  + D+L+ G  P +Y +  V++ACS       G  I+      G L +DV V   LID++ K  G L  A  VF  M  +++V W  MI  F+  G   D I + + M+ +G  P+  T  +VL    +   L+ GK +H   +R  L+ +V +G  L+DMY+KC     +  +R++F+ +   N + W+A+I AYV    CD  +EA+ LF +M+    I P   +  S+L+AC  L+D   G +V+ YA+K G      VGN+++SMYA+ G ++DA + FD +  K+ VSY+AI+ G  +N  ++EA L+F+ +  +G      T   +L   + + A+  G   H   +  G+ ++  ICN LI MYS+CG I    QVF+ M  R++ISW +MI G+  HG    A+  FH ML  G KP+++T++ +LSACSH G+++EG+  FN+M ++  I PRMEHY CMVDLLGR+G L EA  FI  MP  AD  VW  LL ACRVH N ELG   ++ I  +  +     +LLSN++++ G+W D   +R   K + L K  GCSW+E+   +H F  G+ SHPQ+ QI+++L++L   +K +GY  +  FVL D+EEE+KE+ L  HSEK+A+A+ ++S    KPI + KNLRVCGDCH AIK I++ T REI+VRD  RFHH K+G+C+C D+W
Sbjct:   47 YSILLKSCIRFRNFQLGKLVHRKLMQSGLELD--SVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECD--KEAIELFCKMI-SGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSACSHVGMISEGQKHFNSMYKEHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSNLHASAGQWKDVVKIRKSMKERNLIKEAGCSWIEVENRVHRFHVGETSHPQAWQIYQELDQLASKIKEMGYIPDTDFVLHDIEEEQKEQFLFQHSEKIAVAFGLISTSQSKPIRIFKNLRVCGDCHTAIKYISMATGREIVVRDSNRFHHIKNGVCSCNDYW 827          

Query:  463 LLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYK-DVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRS-LSGEVVLGTGLLDMYSK-CQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKC---GIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYA-KEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            + Q    P   TY  +LK+C   +  + G+ +H+     GL  D  V   LI LY+KCG    A+ +F GM  K D+V+W+AM++ F+ + +    I   + M + G  PN     AV+   + AN    G+ ++GF ++   L  +V +G  L+DM+ K    +  A ++FD +  +N V W+ MI  +      R+A+ LF +M L   + P   T  S+L ACT+L  L+ G+++H   I+ G  L+  VG +++ MYAKC   G +DD+ + F++M   + +S++AII+  VQ+G   KEA+ +F  M      P+  +   VL AC +L+    G   ++Y++  G  +   + N LI MY++ G++   R+ FD +  ++++S+NA++ GY  +     A   F+ +   GI     TF  LLS  +  G + +G+     + +      +    IC  ++ +  R G +  A     +M  + +V  W++++     H
Sbjct:   35 MTQQNAPPDLTTYSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYV-PDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKG---GYKSNQCICNALISMYSRCGNIEAAFQVFNEME-DRNVISWTSMITGFAKH 534          

Query: 1066 EMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKM-NSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGF-GTDTSICNVLIDMYSK-CGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYIC----MVDLLGRA---GFLAEAHVFIQKMPFEADVRVWSALLAA 1938
            +++ ++   P   T   +L++C +  +   G+ VH   ++SG +L+++V NT++S+Y+KCG  + A   F+ M N +D VS+SA++S    N    +A+  F  M   GF P+      V+ ACS+      G   + + +  G+   D  +   LIDM+ K  G +    +VFD+M  R++++W  MI  +   G    AI  F  M  +G  PD  T+  +LSAC+  GL+  GK   + +     I   +   +C    +VD+  +    G + ++    ++MP E +V  W+A++ A
Sbjct:   33 DLMTQQNAPPDLTTYSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRV-----IRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMP-EHNVMSWTAIITA 327          

Query:  295 FLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWN-----GPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANA--LSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSIL-----RACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            FL   +  +Y  C  +  A +VFD  P+  ++ WN ++ AYA +     G  +  +HL+  L  S    T+ T   VLK C     L A   +H +A  +GL  DV+V  AL+++Y+KCG + +A+ +F  M  +DVV WN M+ G+   GL  +  Q+  +  ++G  P+  ++  +L     A    L  GK +HG +++  L  +V +   L++MYSK  C  +AR +F+ +   + + W++MI +        E++ LF ++ L + + P   TL SI      +AC  L  L +G+++H +AIK+GFD +  V + IL MY KCG + +A   F+ +++ D V+++++ISGCV NG   +AL I+H M+ S   PD  T   ++ A S + AL+ G   HA  I     +D  +   L+DMY+KCG I    ++F +M  R+I  WNAM+VG   HG    A++ F  M + GI+PD V+FIG+LSACSH+GL +E   + ++M  D+ I P +EHY C+VD LGRAG + EA   I+ MPF+A   +  ALL ACR+  ++E G+ V+ ++       +   VLLSNIY+A  RWDD    R   K + +KK PG SW+++  ++H FV  D+SHPQ+  I++K+EE++  ++  GY  +  FVL DVE+EEKER L YHSEKLAIAY ++S      I V KNLRVCGDCH AIK I+ + +REI++RD  RFHHF+DG+C+C D+W
Sbjct:  113 FLSNNLLTMYSKCGSLSSARQVFDTTPERDLVTWNAILGAYAASVDSNDGNAQEGLHLFRLLRASLGSTTRMTLAPVLKLCLNSGCLWAAEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEFHRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDL-LHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKAGFDSDLHVNSGILDMYIKCGDMVNAGIVFNYISAPDDVAWTSMISGCVDNGNEDQALRIYHRMRQSRVMPDEYTFATLIKASSCVTALEQGRQLHANVIKLDCVSDPFVGTSLVDMYAKCGNIEDAYRLFKKMNVRNIALWNAMLVGLAQHGNAEEAVNLFKSMKSHGIEPDRVSFIGILSACSHAGLTSEAYEYLHSMPNDYGIEPEIEHYSCLVDALGRAGLVQEADKVIETMPFKASASINRALLGACRIQGDVETGKRVAARLFALEPFDSAAYVLLSNIYAAANRWDDVTDARKMMKRKNVKKDPGFSWIDVKNMLHLFVVDDRSHPQADIIYDKVEEMMKTIREDGYVPDTEFVLLDVEDEEKERSLYYHSEKLAIAYGLISTPASTTIRVIKNLRVCGDCHNAIKYISKVFEREIVLRDANRFHHFRDGVCSCGDYW 865          

Query:  508 VLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGF-----SLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRAC--TKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGV-----LPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWF-NAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLE 2007
            +L+       L  G+  H      G A D ++   L+ +Y+KCG L+ A+ VF     +D+V WNA++  +     S  G   + + +   ++ +  S    T+  VL     +  L   + +HG++++  L  +V +   L+++YSKC  +  AR +FD +  ++ V W+ M+  YV     +EA  LF E   R  + P   ++  IL  C      DL  G++VH  A+KSG D +  V N++++MY+K G    A   F+ M   D +S++++IS C Q+   +E++ +F  +   G  PD  T+  +       AC  L  L  G   HA++I  GF +D  + + ++DMY KCG +     VF+ +   D ++W +MI G   +G    A+  +H M  + + PD+ TF  L+ A S    + +G+    N +  D    P +     +VD+  + G + +A+   +KM    ++ +W+A+L     H N E    + K ++  G+E
Sbjct:   83 LLRTAISTHNLLLGKCTHARIVVSGSAGDHFLSNNLLTMYSKCGSLSSARQVFDTTPERDLVTWNAILGAYAASVDSNDGNAQEGLHLFRLLRASLGSTTRMTLAPVLKLCLNSGCLWAAEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEF-HRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKAGFDSDLHVNSGILDMYIKCGDMVNAGIVFNYISAPDDVAWTSMISGCVDNGNEDQALRIYHRMRQSRVMPDEYTFATLIKASSCVTALEQGRQLHANVIKLDCVSDPFVG--TSLVDMYAKCGNIEDAYRLFKKMNVR-NIALWNAMLVGLAQHGNAEEAVNLFKSMKSHGIE 591          

Query:  790 NASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVIC-----DSMREAMALFDEMVLRKEI-NPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAA--LQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPD-----DVTFIGLLSACSHSGLVTEGKH-WFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNN 1956
            ++S   ++L T    + L  GK  H   +    +G+  L   LL MYSKC  ++ AR++FD    ++ V W+A++GAY         + +E + LF   +LR  + + T +TL  +L+ C     L     VH YAIK G + +  V   ++++Y+KCG + DA   FD M  +D V ++ ++ G VQ G  KEA  +F     SG  PD  ++  +L  C       L+ G   H  ++  G  +D S+ N L++MYSK G     R+VF+ M   D+ISWN+MI       L   +++ F  +L  G+KPD      +T      AC    L+ +GK    +A+   F+    +   I  +D+  + G +  A +    +    DV  W+++++ C  + N
Sbjct:   76 SSSQWFSLLRTAISTHNLLLGKCTHARIVVSGSAGDHFLSNNLLTMYSKCGSLSSARQVFDTTPERDLVTWNAILGAYAASVDSNDGNAQEGLHLF--RLLRASLGSTTRMTLAPVLKLCLNSGCLWAAEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEFHRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKAGFDSDLHVNSGI--LDMYIKCGDMVNAGIVFNYISAPDDV-AWTSMISGCVDNGN 473          

Query:  241 KKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            KKI   ++KN   +   S L   + ++Y+ C  +  A +V +E+P   V  WN  + +     P + A+ L+Y +  + ++  ++ +  ++ A + L     G  IH      G  SD+ +  A + +Y K   +      F+ M+ +++ + N +++GF      D   ++L+Q+   G  PN  T +++L T A    L++GKA+HG  ++  ++ +  L   L+++Y+KC    YA ++F  I  ++ V W+A+I  +V  +     + +F++M L +  NP   T  SILR+C+ L+D+  G++VH   +K+  D N  VG  ++ MYAK   ++DA   F+++  +D  +++ I++G  Q+G  ++A+  F  MQ  G  P+  T+   L  CS +A L  G   H+ +I  G   D  + + L+DMY+KCG +     VFD +V+RD +SWN +I GY  HG G  A+  F  ML  G  PD+VTFIG+LSACSH GL+ EGK  FN++S+ + ITP +EHY CMVD+LGRAG   E   FI++M   ++V +W  +L AC++H NIE GE  + K+     E   N +LLSN+++A G WDD   VR     +G+KK PGCSWVE+NG +H F+  D SHP+  +IH KL++L   +  +GY      VL +V + EK+ +L YHSE+LA+A+A+LS    K I + KNLR+CGDCH  +K I+ IT +E++VRD+  FHHFK+G C+C +FW
Sbjct:    9 KKIIFRVIKNG--ICPDSHLWSSLVNVYVKCESLQCARQVLEEMPIQDVQQWNQKLSSANSPYPLQEAVQLFYLMRHTRIRLNQFIFASLISAAASLGDNHYGESIHACVCKYGFESDILISNAFVTMYMKTQSVENGWQFFKAMMIENLASRNNLLSGFCDTETCDQGPRILIQLLVEGFEPNMYTFISILKTCASKGDLNEGKAIHGQVIKSGINPDSHLWNSLVNVYAKCGSANYACKVFGEIPERDVVSWTALITGFV-AEGYGSGLRIFNQM-LAEGFNPNMYTFISILRSCSSLSDVDLGKQVHAQIVKNSLDGNDFVGTALVDMYAKNRFLEDAETIFNRLIKRDLFAWTVIVAGYAQDGQGEKAVKCFIQMQREGVKPNEFTLASSLSGCSRIATLDSGRQLHSMAIKAGQSGDMFVASALVDMYAKCGCVEDAEVVFDGLVSRDTVSWNTIICGYSQHGQGGKALKAFEAMLDEGTVPDEVTFIGVLSACSHMGLIEEGKKHFNSLSKIYGITPTIEHYACMVDILGRAGKFHEVESFIEEMKLTSNVLIWETVLGACKMHGNIEFGERAAMKLFELEPEIDSNYILLSNMFAAKGMWDDVTNVRALMSTRGVKKEPGCSWVEVNGQVHVFLSHDGSHPKIREIHLKLQDLHQKLMSVGYTPNTDHVLHNVSDREKQELLFYHSERLALAFALLSTSTRKTIRIFKNLRICGDCHDFMKSISEITNQELVVRDINCFHHFKNGSCSCQNFW 764          

Query:  349 ASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNS-KDTVSYSAIISGCVQNGYAKEALLIFHHMQLS-GFDPDLATMVGVLPACSH-LAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            + ++FDE PQ  +   N L+  ++ N   + A++L+  L +SG      +   VLK C  L     G+++H      G   DV V T+L+D+Y K   + + + VF  M  K+VV+W +++AG+  +GL +  +++  QMQ  G  PN  T  AVL  +A   A+ +G  +H   ++  L   + +G  +++MYSK   ++ A+ +FD+++ +N V W++MI  +V      EA  LF  M L + +  T     ++++ C  + ++S  +++HC  IK+G D +  +   ++  Y+KC  IDDA + F  M+  ++ VS++AIISG VQNG    A+ +F  M+   G +P+  T   VL AC+   A+++ G   H+ SI  GF     + + L+ MY+K G I    +VF R V RD++SWN+MI GY  HG G  ++  F  M +  ++ D +TFIG++SAC+H+GLV EG+ +F+ M +D++I P MEHY CMVDL  RAG L +A   I KMPF A   +W  LLAACRVH N++LGE  ++K+     + +   VLLSNIY+  G W + A VR     + +KK  G SW+E+      F+ GD SHPQS +I+ KLEEL + +K  GY  +  +VL DVEEE KE IL  HSE+LAIA+ +++  PG PI + KNLRVCGDCH  IK+I+ I  R+I+VRD  RFHHFK G C+C D+W
Sbjct:   45 SQQLFDETPQQGLSRNNHLLFEFSRNDQNKEALNLFLGLRRSGSPTDGSSLSCVLKVCGCLFDRIVGKQVHCQCIKCGFVEDVSVGTSLVDMYMKTESVEDGERVFDEMRVKNVVSWTSLLAGYRQNGLNEQALKLFSQMQLEGIKPNPFTFAAVLGGLAADGAVEKGVQVHTMVIKSGLDSTIFVGNSMVNMYSKSLMVSDAKAVFDSMENRNAVSWNSMIAGFVTNGLDLEAFELFYRMRL-EGVKLTQTIFATVIKLCANIKEMSFAKQLHCQVIKNGSDFDLNIKTALMVAYSKCSEIDDAFKLFCMMHGVQNVVSWTAIISGYVQNGRTDRAMNLFCQMRREEGVEPNEFTFSSVLNACAAPTASVEQGKQFHSCSIKSGFSNALCVSSALVTMYAKRGNIESANEVFKRQVDRDLVSWNSMISGYAQHGCGKKSLKIFEEMRSKNLELDGITFIGVISACTHAGLVNEGQRYFDLMVKDYHIVPTMEHYSCMVDLYSRAGMLEKAMDLINKMPFPAGATIWRTLLAACRVHLNVQLGELAAEKLISLQPQDSAAYVLLSNIYATAGNWQERAKVRKLMDMKKVKKEAGYSWIEVKNKTFSFMAGDLSHPQSDRIYLKLEELSIRLKDAGYYPDTKYVLHDVEEEHKEVILSQHSERLAIAFGLIATPPGTPIQIVKNLRVCGDCHTVIKLISKIEGRDIVVRDSNRFHHFKGGSCSCGDYW 770          

Query:  319 LYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAI-DVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLT-DLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHG-----ACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRM-VTRDIISWNAMIVGYGIH 1641
            +Y+    V+   RVFDE+   +V+ W  L+  Y  NG  E+A+ L+  +   G+KP  +T+  VL   +   A+E G ++H      GL S ++V  +++++Y+K   +++A+ VF  M  ++ V+WN+MIAGF  +GL  +  ++  +M+  G     +    V+   A    +S  K +H   ++     ++ + T L+  YSKC  I  A ++F  +  V+N V W+A+I  YV       AM LF +M   + + P   T  S+L AC   T  + +G++ H  +IKSGF     V + +++MYAK G I+ A   F +   +D VS++++ISG  Q+G  K++L IF  M+    + D  T +GV+ AC+H   +  G          Y IV          + ++D+YS+ G + +   + ++M        W  ++    +H
Sbjct:  136 MYMKTESVEDGERVFDEMRVKNVVSWTSLLAGYRQNGLNEQALKLFSQMQLEGIKPNPFTFAAVLGGLAADGAVEKGVQVHTMVIKSGLDSTIFVGNSMVNMYSKSLMVSDAKAVFDSMENRNAVSWNSMIAGFVTNGLDLEAFELFYRMRLEGVKLTQTIFATVIKLCANIKEMSFAKQLHCQVIKNGSDFDLNIKTALMVAYSKCSEIDDAFKLFCMMHGVQNVVSWTAIISGYVQNGRTDRAMNLFCQMRREEGVEPNEFTFSSVLNACAAPTASVEQGKQFHSCSIKSGFSNALCVSSALVTMYAKRGNIESANEVFKRQVDRDLVSWNSMISGYAQHGCGKKSLKIFEEMRSKNLELDGITFIGVISACTHAGLVNEGQRYFDLMVKDYHIV----PTMEHYSCMVDLYSRAGMLEKAMDLINKMPFPAGATIWRTLLAACRVH 580          

Query:  241 KKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML-YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQK-AGTSPNASTIVAVLPTVAQANA-LSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVG-NTILSMYAKCGIIDDAVRFFDKM 1284
            K +  H +   + L  T F+   + ++Y     V  A  VFD +   + + WN +I  +  NG    A  L+Y +   GVK T+  +  V+K C+ ++ +   +++H      G   D+ + TAL+  Y+KC  + +A  +F  M   ++VV+W A+I+G+  +G  D  + +  QM++  G  PN  T  +VL   A   A + QGK  H  S++   S  + + + L+ MY+K   I  A  +F     ++ V W++MI  Y      ++++ +F+EM   K +    +T   ++ ACT    ++ G+R     +K    + TM   + ++ +Y++ G+++ A+   +KM
Sbjct:  211 KGVQVHTMVIKSGLDSTIFVGNSMVNMYSKSLMVSDAKAVFDSMENRNAVSWNSMIAGFVTNGLDLEAFELFYRMRLEGVKLTQTIFATVIKLCANIKEMSFAKQLHCQVIKNGSDFDLNIKTALMVAYSKCSEIDDAFKLFCMMHGVQNVVSWTAIISGYVQNGRTDRAMNLFCQMRREEGVEPNEFTFSSVLNACAAPTASVEQGKQFHSCSIKSGFSNALCVSSALVTMYAKRGNIESANEVFKRQVDRDLVSWNSMISGYAQHGCGKKSLKIFEEM-RSKNLELDGITFIGVISACTHAGLVNEGQRYFDLMVKDYHIVPTMEHYSCMVDLYSRAGMLEKAMDLINKM 561          

Query: 1237 AKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEG 1764
            +K   +  + + FD+   +     + ++    +N   KEAL +F  ++ SG   D +++  VL  C  L     G   H   I  GF  D S+   L+DMY K   +  G +VFD M  ++++SW +++ GY  +GL   A+  F  M   GIKP+  TF  +L   +  G V +G
Sbjct:   37 SKLSTLSHSQQLFDETPQQGLSRNNHLLFEFSRNDQNKEALNLFLGLRRSGSPTDGSSLSCVLKVCGCLFDRIVGKQVHCQCIKCGFVEDVSVGTSLVDMYMKTESVEDGERVFDEMRVKNVVSWTSLLAGYRQNGLNEQALKLFSQMQLEGIKPNPFTFAAVLGGLAADGAVEKG 212          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVD---LASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKA--GTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKD--TVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQ---DVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            CI S S  + K IH  ++ N       ++L+ K+  LY     +D    A ++F+E+P+ ++  WN +I AYA    +  A  ++  +L+ GV P  +T+   L+ C  L++ + G+++H    A G   D +V  ALID+YAKC        VF  M  ++ V WN++I+  +  G ++D + + ++MQ++  G  P+  T   +L   A     +QG+ +H   +R +++  +++ T L+ MYS+C  + YA+ IF+ +  +N   W++MI  Y      +EA+ LF +M L   I P   +L S+L +C  L+D  +GR +H + +++  +   ++   ++ MYAKCG +D A + +D+   KD  T  +++I++G    G  KE+   F  M  S  + D+ TMV ++    +L  L+                       L+DMYSKCG I + R VFD M  ++I+SWNAMI GY  HG    A+  +  M   G+ P++VTF+ +LSACSH+GLV EG   F +M ED+NI  + EHY CMVDLLGRAG L +A  F++KMP E +V  W ALL ACRVH ++++G   ++++     +  G  V++SNIY+A GRW +   +R   K +G+KK PG SW+EIN  I  F  G ++HP++ +I+  L  L +  K LGY  + SF+LQ   D++EEE+E  LL HSE+LA++  ++SL     I V KNLR+CGDCH A K I+ IT R II RD  RFHHF++G C+C D+W
Sbjct:   81 CIDSNSFQRGKSIHTQMISNG--YNPDAYLMTKILMLYARSGCLDDLCYARKLFEEMPERNLTAWNTMILAYARVDDYMEAWGIFDRMLKIGVCPDNFTFASALRVCGALRSRDGGKQVHSKLIACGFKGDTFVGNALIDMYAKCDDEESCLKVFDEMGERNQVTWNSIISAEAQFGHFNDALVLFLRMQESEDGIQPDQFTFTTLLTLCANQRNDNQGRQIHAHLIRANITKNIIVETELVHMYSECGRLNYAKEIFNRMAERNAYSWNSMIEGYQQNGETQEALRLFKQMQLNG-IKPDCFSLSSMLSSCVSLSDSQKGRELHNFIVRNTMEEEGILQVVLVDMYAKCGSMDYAWKVYDQTIKKDRNTALWNSILAGYANKGLKKESFNHFLEMLESDIEYDVLTMVTIV----NLLVLE---------------------TALVDMYSKCGAITKARTVFDNMNGKNIVSWNAMISGYSKHGCSKEALILYEEMPKKGMYPNEVTFLAILSACSHTGLVEEGLRIFTSMQEDYNIEAKAEHYTCMVDLLGRAGRLEDAKEFVEKMPIEPEVSTWGALLGACRVHKDMDMGRLAAQRLFELDPQNPGPYVIMSNIYAAAGRWKEVEDIRQMMKMKGVKKDPGVSWIEINSEIQIFHAGSKTHPKTEEIYNNLRHLTLQSKGLGYIPDTSFILQNVKDIKEEEEEEYLLQHSERLALSLGLISLPKKSTIRVFKNLRICGDCHTATKFISKITGRRIIARDTNRFHHFENGKCSCGDYW 832          

Query:  421 WNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCG---GLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKE-INPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRD--IISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFI----------GLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEA---DVRVWSALLAACRVHNNIELGEEVSKKIQ 1992
            +NGP        +    S V P  Y+   +++ C    + + G+ IH    + G   D Y+ T ++ LYA+ G    L  A+ +F  M  +++ AWN MI  ++    Y +   +  +M K G  P+  T  + L       +   GK +H   +     G+  +G  L+DMY+KC       ++FD +  +N+V W+++I A        +A+ LF  M   ++ I P   T  ++L  C    + ++GR++H + I++    N +V   ++ MY++CG ++ A   F++M  ++  S++++I G  QNG  +EAL +F  MQL+G  PD  ++  +L +C  L+  Q G   H + + +    +  +  VL+DMY+KCG ++   +V+D+ + +D     WN+++ GY   GL   + + F  ML + I+ D +T +           L+   S  G +T+ +  F+ M+        +  +  M+    + G   EA +  ++MP +    +   + A+L+AC     +E G  +   +Q
Sbjct:   50 FNGPDSPKPTSIHTKPASDVNPLPYSS--LIQDCIDSNSFQRGKSIHTQMISNGYNPDAYLMTKILMLYARSGCLDDLCYARKLFEEMPERNLTAWNTMILAYARVDDYMEAWGIFDRMLKIGVCPDNFTFASALRVCGALRSRDGGKQVHSKLIACGFKGDTFVGNALIDMYAKCDDEESCLKVFDEMGERNQVTWNSIISAEAQFGHFNDALVLFLRMQESEDGIQPDQFTFTTLLTLCANQRNDNQGRQIHAHLIRANITKNIIVETELVHMYSECGRLNYAKEIFNRMAERNAYSWNSMIEGYQQNGETQEALRLFKQMQLNGIKPDCFSLSSMLSSCVSLSDSQKGRELHNFIVRNTMEEEGILQVVLVDMYAKCGSMDYAWKVYDQTIKKDRNTALWNSILAGYANKGLKKESFNHFLEMLESDIEYDVLTMVTIVNLLVLETALVDMYSKCGAITKARTVFDNMN-----GKNIVSWNAMISGYSKHGCSKEALILYEEMPKKGMYPNEVTFLAILSACSHTGLVEEGLRIFTSMQ 585          

Query:  205 TTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKD--VVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGN--TILSMYAKCGIIDDAVRFFDKMNSKDTVS-YSAIISGC 1329
            T C   ++  Q ++IH HL++    +     +  ++ H+Y  C +++ A  +F+ + + +   WN +I  Y  NG  + A+ L+  +  +G+KP  ++   +L +C  L   + GRE+H       +  +  +   L+D+YAKCG +  A  V+   + KD     WN+++AG++  GL  ++    ++M ++    +  T+V ++                           +VL T L+DMYSKC  I  AR +FD ++ KN V W+AMI  Y      +EA+ L++EM  +K + P  VT  +IL AC+    +  G R+   +++  +++     +   ++ +  + G ++DA  F +KM  +  VS + A++  C
Sbjct:  286 TLCANQRNDNQGRQIHAHLIR--ANITKNIIVETELVHMYSECGRLNYAKEIFNRMAERNAYSWNSMIEGYQQNGETQEALRLFKQMQLNGIKPDCFSLSSMLSSCVSLSDSQKGRELHNFIVRNTMEEEGILQVVLVDMYAKCGSMDYAWKVYDQTIKKDRNTALWNSILAGYANKGLKKESFNHFLEMLESDIEYDVLTMVTIV-------------------------NLLVLETALVDMYSKCGAITKARTVFDNMNGKNIVSWNAMISGYSKHGCSKEALILYEEMP-KKGMYPNEVTFLAILSACSHTGLVEEGLRIFT-SMQEDYNIEAKAEHYTCMVDLLGRAGRLEDAKEFVEKMPIEPEVSTWGALLGAC 636          

Query: 1084 EINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDD---AVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAA--GIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLE 2007
            ++NP P +  S+++ C       RG+ +H   I +G++ +  +   IL +YA+ G +DD   A + F++M  ++  +++ +I    +     EA  IF  M   G  PD  T    L  C  L +   G   H+  I  GF  DT + N LIDMY+KC       +VFD M  R+ ++WN++I      G    A+  F  M  +  GI+PD  TF  LL+ C++     +G+   +A     NIT  +     +V +    G L  A     +M  E +   W++++   + +   +    + K++Q  G++
Sbjct:   68 DVNPLPYS--SLIQDCIDSNSFQRGKSIHTQMISNGYNPDAYLMTKILMLYARSGCLDDLCYARKLFEEMPERNLTAWNTMILAYARVDDYMEAWGIFDRMLKIGVCPDNFTFASALRVCGALRSRDGGKQVHSKLIACGFKGDTFVGNALIDMYAKCDDEESCLKVFDEMGERNQVTWNSIISAEAQFGHFNDALVLFLRMQESEDGIQPDQFTFTTLLTLCANQRNDNQGRQ-IHAHLIRANITKNIIVETELVHMYSECGRLNYAKEIFNRMA-ERNAYSWNSMIEGYQQNGETQEALRLFKQMQLNGIK 376          

Query:  499 YPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIK-SGFDLNTMVGNTILSMYAKCGIIDDAVR-------------------------------------------FFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y  +L+ C  L  L  G ++H      G+    ++ + L+++Y + G + +A+ +F  M  ++V +W A++  +   G Y++TI++   M   G  P+      V    ++      GK ++ + L     G   +   +LDM+ KC  +  ARR F+ I+ K+   W+ M+  Y      ++A+ +F +MVL + + P  +T+ S + ACT L+ L  GR +H Y IK    D + +VGN+++  YAKC  ++ A R                                            F +++++D V +++IIS C Q+G +  AL +   M LS  + +  TMV  LPACS LAAL+ G   H + I  G  T   I N LIDMY +CG I + R++FD M  RD++SWN MI  YG+HG GM A++ F      G+KP+ +TF  LLSACSHSGL+ EG  +F  M  ++ + P +E Y CMVDLL RAG   E   FI+KMPFE +  VW +LL ACR+H N +L E  ++ +     + +GN VL++NIYSA GRW+DAA +R   K +G+ K PGCSW+E+   +H FV GD SHP   QI  K+E L  D+K +GY  + +FVLQDV+E+EKE  L  HSEK+A+A+ ++S   G P+ + KNLRVCGDCH+A K I+ + KR+II+RD  RFHHF DG+C+C D+W
Sbjct:   13 YASILQKCRKLYNLRLGFQVHAQLVVNGVDVCEFLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVL-EGVKPNSITIASAVSACTNLSLLRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIKQTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREMNLSNVEVNTVTMVSALPACSKLAALRQGKEIHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLMPQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMGLKPNHITFTNLLSACSHSGLIEEGWKYFKMMKTEYAMDPAVEQYACMVDLLSRAGQFNETLEFIEKMPFEPNAAVWGSLLGACRIHCNPDLAEYAARYLFELEPQSSGNYVLMANIYSAAGRWEDAAKIRCLMKERGVTKPPGCSWIEVKRKLHSFVVGDTSHPLMEQISAKMESLYFDIKEIGYVPDTNFVLQDVDEDEKEFSLCGHSEKIALAFGLISTTAGTPLRIIKNLRVCGDCHSATKFISKVEKRDIIMRDNYRFHHFVDGVCSCGDYW 729          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLR-RSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMI------------GAYVICDSMREAMALFDEMVLR------------------------------KEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSI--CNVLIDMYSKCGKINRGRQVFDRM-VTRDIISWNAMIVGYGIH 1641
            C +  +L    ++H  L+ N   + +  FL  ++  +Y     V+ A R+FD++ + +V  W  ++  Y   G +E  I L+Y ++  GV+P  + +P V KACS L+    G++++ +  ++G   +  V  +++D++ KCG +  A+  F  + +KDV  WN M++G++  G +   + +  +M   G  PN+ TI + +      + L  G+ +HG+ ++   L  ++++G  L+D Y+KC+ +  ARR F  I   + V W+AM+             A      M  A ++F E+  R                                +    VT+ S L AC+KL  L +G+ +H + I+ G D    + N+++ MY +CG I  + R FD M  +D VS++ +IS    +G+  +A+ +F   +  G  P+  T   +L ACSH   ++ G   +   +   +  D ++     ++D+ S+ G+ N   +  ++M    +   W +++    IH
Sbjct:   20 CRKLYNLRLGFQVHAQLVVNGVDVCE--FLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVLEGVKPNSITIASAVSACTNLSLLRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIKQTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREMNLSNVEVNTVTMVSALPACSKLAALRQGKEIHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLMPQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMGLKPNHITFTNLLSACSHSGLIEEG-WKYFKMMKTEYAMDPAVEQYACMVDLLSRAGQFNETLEFIEKMPFEPNAAVWGSLLGACRIH 539          

Query: 1375 MQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYIC----MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSA 2049
            M L+  D  +     +L  C  L  L+ G   HA  +V+G      + + L+++Y + G +   R++FD+M  R++ SW A++  Y   G     I  F+ M+  G++PD   F  +  ACS       GK  +     D+ ++   E   C    ++D+  + G +  A  F +++ F+ DV +W+ +++        +    V +K+  +G++   N + +++  SA
Sbjct:    1 MDLTNPDECIEIYASILQKCRKLYNLRLGFQVHAQLVVNGVDVCEFLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSELKNYRVGKDVY-----DYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFK-DVFMWNIMVSGYTSKGEFKKALNVFRKMVLEGVK--PNSITIASAVSA 221          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCAD 2514
            C   ++  +  ++H ++ K  TRL     L   +  +++    +  A  VF ++ +  +  WN+L+  YA  G F+ A++LY+ +L  G++P  YT+P VL+ C GL  L  GRE+H H    G  SDV V  ALI +Y KCG +  A+ VF  M  +D ++WNAMI+G+  + +  + +++   M++    P+  T+ +V+           G+ +HG+ ++     EV +   L+ M+S   C   A  +F  ++ K+ V W+AMI  Y       +A+  +  M   + + P  +T+ S+L AC  L  L +G  +H +A ++G     +V N+++ MY+KC  ID A+  F ++ +K+ +S+++II G   N  + EAL  F  M LS   P+  T+V VL AC+ + AL  G   HA+++  G G D  + N L+DMY +CG++      F+    +D+ SWN ++ GY   G G  A+  FH M+ + + PD++TF  LL ACS SG+VT+G  +F +M   F+I P ++HY  +VDLLGRAG L +A+ FI+KMP + D  +W ALL ACR++ N+ELGE  ++ I     +  G  +LL N+Y+  G+WD+ A VR   +   L   PGCSWVE+ G +H F+ GD  HPQ  +I+  LE     M+  G          D++  + E I   HSE+LAIA+ +++  PG PI VTKNL +C +CH  +K I+ + +R I VRD  +FHHFKDG+C+C D
Sbjct:  104 CEWKRAASEGSRVHSYVSKTVTRLGVR--LGNALLSMFVRFGDLVEAWYVFGKMAERDLFSWNVLVGGYAKAGYFDEALNLYHRMLWVGIRPDVYTFPCVLRTCGGLPDLARGREVHLHVIRYGFESDVDVVNALITMYVKCGDIFSARLVFDRMPRRDRISWNAMISGYFENDVCLEGLRLFFMMREFFVDPDLMTMTSVISACEALGDERLGREVHGYVIKTGFVAEVSVNNSLIQMHSSVGCWDEAEMVFSKMEFKDLVSWTAMISGYEKNGLPEKAVETYTIME-HEGVVPDEITIASVLSACAGLGLLDKGIMLHEFADRTGLTSYVIVANSLIDMYSKCRCIDKALEVFHRIPNKNVISWTSIILGLRLNYRSFEALFFFQQMILS-LKPNSVTLVSVLSACARIGALSCGKEIHAHALRTGLGFDGFLPNALLDMYVRCGRMEPAWNQFNSC-EKDVASWNILLTGYAQQGKGGLAVELFHKMIESDVNPDEITFTSLLCACSRSGMVTDGLEYFESMEHKFHIAPNLKHYASVVDLLGRAGRLEDAYEFIKKMPIDPDPAIWGALLNACRIYQNVELGELAAQHIFEMDTKSVGYYILLCNLYADSGKWDEVARVRKIMRENRLTVDPGCSWVEVAGQVHAFLTGDDFHPQIKEINAVLEGFYEKMEATGLSMSKDSRRDDIDASKAE-IFCGHSERLAIAFGLINTVPGTPIWVTKNLYMCENCHNTVKFISKVVRRGISVRDTEQFHHFKDGVCSCGD 865          

Query:  397 NLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKH-WFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALL 1932
            N LI      G  E+A+     + +  V   + TY  +L+ C   +A   G  +H +         V +  AL+ ++ + G L EA  VF  M  +D+ +WN ++ G++  G +D+ + +  +M   G  P+  T   VL T      L++G+ +H   +R     +V +   L+ MY KC  I  AR +FD +  ++ + W+AMI  Y   D   E + LF  M+    ++P  +T+ S++ AC  L D   GR VH Y IK+GF     V N+++ M++  G  D+A   F KM  KD VS++A+ISG  +NG  ++A+  +  M+  G  PD  T+  VL AC+ L  L  G   H ++   G  +   + N LIDMYSKC  I++  +VF R+  +++ISW ++I+G  ++     A+  F  M+ + +KP+ VT + +LSAC+  G ++ GK    +A+         + +   ++D+  R G +  A  + Q    E DV  W+ LL
Sbjct:   63 NSLILELCLKGDLEKALIHLDSMQELQVSVEEETYIALLRLCEWKRAASEGSRVHSYVSKTVTRLGVRLGNALLSMFVRFGDLVEAWYVFGKMAERDLFSWNVLVGGYAKAGYFDEALNLYHRMLWVGIRPDVYTFPCVLRTCGGLPDLARGREVHLHVIRYGFESDVDVVNALITMYVKCGDIFSARLVFDRMPRRDRISWNAMISGYFENDVCLEGLRLF-FMMREFFVDPDLMTMTSVISACEALGDERLGREVHGYVIKTGFVAEVSVNNSLIQMHSSVGCWDEAEMVFSKMEFKDLVSWTAMISGYEKNGLPEKAVETYTIMEHEGVVPDEITIASVLSACAGLGLLDKGIMLHEFADRTGLTSYVIVANSLIDMYSKCRCIDKALEVFHRIPNKNVISWTSIILGLRLNYRSFEALFFFQQMILS-LKPNSVTLVSVLSACARIGALSCGKEIHAHALRTGLGFDGFLPN--ALLDMYVRCGRMEPA--WNQFNSCEKDVASWNILL 569          

Query: 1018 AYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLA 1935
            A +  DSM+E     +E            T  ++LR C      S G RVH Y  K+   L   +GN +LSM+ + G + +A   F KM  +D  S++ ++ G  + GY  EAL ++H M   G  PD+ T   VL  C  L  L  G   H + I +GF +D  + N LI MY KCG I   R VFDRM  RD ISWNAMI GY  + + +  +  F  M    + PD +T   ++SAC   G    G+     + +       +     ++ +    G   EA +   KM F+ D+  W+A+++
Sbjct:   78 ALIHLDSMQELQVSVEEE-----------TYIALLRLCEWKRAASEGSRVHSYVSKTVTRLGVRLGNALLSMFVRFGDLVEAWYVFGKMAERDLFSWNVLVGGYAKAGYFDEALNLYHRMLWVGIRPDVYTFPCVLRTCGGLPDLARGREVHLHVIRYGFESDVDVVNALITMYVKCGDIFSARLVFDRMPRRDRISWNAMISGYFENDVCLEGLRLFFMMREFFVDPDLMTMTSVISACEALGDERLGREVHGYVIKT-GFVAEVSVNNSLIQMHSSVGCWDEAEMVFSKMEFK-DLVSWTAMIS 370          

Query:  205 TTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAK-ALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGM-LYKDVVAWNAMI 711
            + C R  +L   K+IH H L+  T L    FL   +  +Y+ C +++ A   F+   +  V  WN+L+  YA  G    A+ L++ +++S V P + T+  +L ACS    +  G E  +  +    +A ++    +++DL  + G L +A    + M +  D   W A++
Sbjct:  505 SACARIGALSCGKEIHAHALR--TGLGFDGFLPNALLDMYVRCGRMEPAWNQFNSC-EKDVASWNILLTGYAQQGKGGLAVELFHKMIESDVNPDEITFTSLLCACSRSGMVTDGLEYFESMEHKFHIAPNLKHYASVVDLLGRAGRLEDAYEFIKKMPIDPDPAIWGALL 672          

Query:  199 YSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQ----------------------------NGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y +  +  ++L Q +++H     +   + +   +  K+ + Y     +D A  +FD +     + W++++  +A  G +      + +L++ G +P  YT PFV++AC  L+ L+                      AL+D+Y KC  + +A+ +F  M  +D+V W  MI G++  G  ++++ +  +M++ G  P+   +V V+   A+  A+ + + +  +  R+    +V+LGT ++DMY+KC C+  AR IFD ++ KN + WSAMI AY      R+A+ LF  M+L   + P  +TL S+L AC    +L++ R+VH  A   G   N +V N ++  Y+    +DDA   FD M  +D+VS+S ++ G  +                             G A E+L++F  M+  G  PD   MV V+ AC+ L A+        Y     F  D  +   +IDM++KCG +   R++FDRM  +++ISW+AMI  YG HG G  A+  F  ML +GI P+ +T + LL ACSH+GLV EG  +F+ M ED+++   ++HY C+VDLLGRAG L EA   I+ M  E D  +W A L ACR H ++ L E+ +  +     +  G+ +LLSNIY+  GRW+D A  R     + LKK PG +W+E++   H F  GD +HP+S +I+E L+ L   ++ +GY  + +FVL DV+EE K  IL  HSEKLAIA+ +++     PI + KNLRVCGDCH   K+++ IT R IIVRD  RFHHFK+G C+C D+W
Sbjct:   84 YISALVNCRNLTQVRQVHAQA--SVHGMLENIVVANKLIYFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYINCFGTFRELIRCGARPDNYTLPFVIRACRDLKNLQ---------------------MALVDMYVKCREIEDARFLFDKMQERDLVTWTVMIGGYAECGKANESLVLFEKMREEGVVPDKVAMVTVVFACAKLGAMHKARIIDDYIQRKKFQLDVILGTAMIDMYAKCGCVESAREIFDRMEEKNVISWSAMIAAYGYHGQGRKALDLF-RMMLSSGMLPDKITLASLLYACINCRNLTQVRQVHAQASVHGMLQNLIVANKLVHFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYMNCFGTFRELIRCGARPDNYTLPFCGNANESLVLFDKMREEGVVPDKVAMVTVVFACAKLGAMHKARTIDDYIQRKKFQLDVILGTAMIDMHAKCGCVESAREIFDRMEEKNVISWSAMIAAYGYHGQGRKALDLFPMMLRSGILPNKITLVSLLYACSHAGLVEEGLRFFSLMWEDYSVRADVKHYTCVVDLLGRAGRLDEALKLIESMTVEKDEGLWGAFLGACRTHKDVVLAEKAATSLLELQPQNPGHYILLSNIYANAGRWEDVAKTRDLMSQRRLKKIPGWTWIEVDNKSHQFSVGDTTHPRSKEIYEMLKSLGNKLELVGYVPDTNFVLHDVDEELKIGILYSHSEKLAIAFGLIATPEHTPIRIIKNLRVCGDCHTFCKLVSAITGRVIIVRDANRFHHFKEGACSCGDYW 861          

Query:  505 FVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKE-INPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHV---FIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGL 2004
            F + A    + L   R++H  A   G+  ++ V   LI  Y+    L +A  +F GM  +D V+W+ M+ GF+  G Y +      ++ + G  P+  T    LP V +A               R L     L   L+DMY KC+ I  AR +FD +  ++ V W+ MIG Y  C    E++ LF++M  R+E + P  V + +++ AC KL  + + R +  Y  +  F L+ ++G  ++ MYAKCG ++ A   FD+M  K+ +S+SA+I+    +G  ++AL +F  M  SG  PD  T+  +L AC +   L      HA + VHG   +  + N L+  YS    ++    +FD M  RD +SW+ M+ G+   G  M     F  ++  G +PD+ T    L  C   G   E    F+ M E+  + P     + +V    + G + +A     +IQ+  F+ DV + +A++        +E   E+  +++ K +
Sbjct:   83 FYISALVNCRNLTQVRQVHAQASVHGMLENIVVANKLIYFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYINCFGTFRELIRCGARPDNYT----LPFVIRAC--------------RDLKN---LQMALVDMYVKCREIEDARFLFDKMQERDLVTWTVMIGGYAECGKANESLVLFEKM--REEGVVPDKVAMVTVVFACAKLGAMHKARIIDDYIQRKKFQLDVILGTAMIDMYAKCGCVESAREIFDRMEEKNVISWSAMIAAYGYHGQGRKALDLFRMMLSSGMLPDKITLASLLYACINCRNLTQVRQVHAQASVHGMLQNLIVANKLVHFYSYYRALDDAYGLFDGMCVRDSVSWSVMVGGFAKVGDYMNCFGTFRELIRCGARPDNYT----LPFC---GNANESLVLFDKMREE-GVVPDKVAMVTVVFACAKLGAMHKARTIDDYIQRKKFQLDVILGTAMIDMHAKCGCVESAREIFDRMEEKNV 555          

Query:  646 AEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQC---IAYARRIFDAIDVKNEVCWSAMIGAYVI---CDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            A A  VF  M  +++V W  MI  F+  G   D I + + M+ +G  P+  T  +VL    +   L+ GK +H   +R  L+ +V +G  L+DMY+KC     +  +R++F+ +   N + W+A+I AY     CD  +EA+ LF +M+    I P   +  S+L+AC  L+D   G +V+ YA+K G      VGN+++SMYA+ G ++DA + FD +  K+ VSY+AI+ G  +N  ++EA L+F+ +  +G      T   +L   + + A+  G   H   +  G+ ++  ICN LI MYS+CG I    QVF+ M  R++ISW +MI G+  HG    A+  FH ML  G KP+++T++ +LSACSH G+++EG+  FN+M ++  I PRMEHY CMVDLLGR+G L EA  FI  MP  AD  VW  LL ACRVH N ELG   ++ I  +  +     +LLSN++++ G+W D   +R   K + L K  GCSW+E+   +H F  G+ SHPQ+ QI+++L++L   +K +GY  +  FVL D+EEE+KE+ L  HSEK+A+A+ ++S    KPI + KNLRVCGDCH AIK I++ T REI+VRD  RFHH K+G+C+C D+W
Sbjct:    7 APAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYAQSGECD--KEAIELFCKMI-SGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSACSHVGMISEGQKHFNSMYKEHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSNLHASAGQWKDVVKIRKSMKERNLIKEAGCSWIEVENRVHRFHVGETSHPQAWQIYQELDQLASKIKEMGYIPDTDFVLHDIEEEQKEQFLFQHSEKIAVAFGLISTSQSKPIRIFKNLRVCGDCHTAIKYISMATGREIVVRDSNRFHHIKNGVCSCNDYW 634          

Query:  349 ASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKC---GGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYD-DTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIV--HGFGTDTSICNVLIDMYSKCGKINRGRQVFDRM-VTRDIISWNAMIVGYGIHG 1644
            A +VFD++P+ +++ W L+I  +A  G    AI L+ D+  SG  P ++TY  VL AC+ L  L  G+++H     LGLA DV V  +L+D+YAKC   G + +++ VF  M   +V++W A+I  ++  G  D + I++  +M      PN  +  +VL      +    G+ ++ ++++  ++    +G  L+ MY++   +  AR+ FD +  KN V ++A++  Y       EA  LF+E +    I  +  T  S+L     +  + +G ++H   +K G+  N  + N ++SMY++CG I+ A + F++M  ++ +S++++I+G  ++G+A  AL +FH M  +G  P+  T V VL ACSH+  +  G   H  S+   HG          ++D+  + G +    +  + M +  D + W  ++    +HG
Sbjct:    9 AYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYAQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNE-IADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSACSHVGMISEGQ-KHFNSMYKEHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHG 445          

Query:  319 LYITC---NQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFER-AIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGN--TILSMYAKCGIIDDAVRFFDKMN-SKDTVSYSAIISGCVQNG 1341
            +Y  C     VD + +VF+++P+ +V+ W  +I AYA +G  ++ AI L+  ++   ++P  +++  VLKAC  L     G +++ +A  LG+AS   V  +LI +YA+ G + +A+  F  +  K++V++NA++ G++ +   ++   +  ++   G   +A T  ++L   A   A+ +G+ +HG  L+        +   L+ MYS+C  I  A ++F+ ++ +N + W++MI  +        A+ +F +M L     P  +T  ++L AC+ +  +S G++ H  ++     +   + +   ++ +  + G++ +A+ F + M    D + +  ++  C  +G
Sbjct:  100 MYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYAQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKM-LETGTKPNEITYVAVLSACSHVGMISEGQK-HFNSMYKEHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHG 445          

Query:  226 SLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAG-REIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGM-LYKDVVAWNAMIAGFSLHG 732
            ++ + ++IH  LLK     K    +   +  +Y  C  ++ A +VF+E+   +VI W  +I  +A +G   RA+ +++ +L++G KP + TY  VL ACS +  +  G +  +   K  G+   +     ++DL  + G L EA      M L  D + W  ++    +HG
Sbjct:  277 AMGKGEQIHGRLLKGG--YKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSACSHVGMISEGQKHFNSMYKEHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHG 445          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            CI+SKSL +AKKIHQH LKNT+     S +L K+  LY++CNQV LA R+FDEIP PSVILWN +IRAYAWNGPF+ AI LY+ +L  GV+P KYTYPFVLKACSGL A+E G EIH HAK  GL SDV+VCTAL+D YAKCG L EAQ +F  M ++DVVAWNAMIAG SL+GL DD +Q+++QMQ+ G  PN+STIV VLPTV +A AL  GKA+HG+ +RRS    VV+GTGLLDMY+KCQC+ YAR+IFD + V+NEV WSAMIG YV  D M+EA+ LFD+M+L+  ++PTPVTLGS+LRAC KLTDLSRGR++HCY IK G  L+ ++GNT+LSMYAKCG+IDDA+RFFD+MN KD+VS+SAI+SGCVQNG A  AL IF  MQLSG DPDL TM+GVLPACSHLAALQHG C H Y IV GF TDT ICN LIDMYSKCGKI+  R+VF+RM   DI+SWNAMI+GYGIHGLGM A+  FH +LA G+KPDD+TFI LLS+CSHSGLV EG+ WF+AMS DF+I PRMEH ICMVD+LGRAG + EAH FI+ MPFE DVR+WSALL+ACR+H NIELGEEVSKKIQ  G E TGN VLLSNIYSA GRWDDAA++RI QK  GLKK PGCSW+EINGI+H FVGGDQSH Q +QI+ KLEELLV+MKRLGY AE SFV QDVEEEEKE+ILLYHSEKLAIA+ IL+L+ G+PILVTKNLRVCGDCH AIK +TLITKREI VRD  RFHHFK+G CNC DFW
Sbjct:   18 CIQSKSLTEAKKIHQHFLKNTSNAD--SSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVASDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGSVLDILLGNTLLSMYAKCGVIDDAIRFFDEMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHGFCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMDRHDIVSWNAMIIGYGIHGLGMEALGLFHDLLALGLKPDDITFICLLSSCSHSGLVMEGRLWFDAMSRDFSIVPRMEHCICMVDILGRAGLIDEAHHFIRNMPFEPDVRIWSALLSACRIHKNIELGEEVSKKIQSLGPESTGNFVLLSNIYSAAGRWDDAAHIRITQKDWGLKKIPGCSWIEINGIVHAFVGGDQSHLQLSQINRKLEELLVEMKRLGYQAECSFVFQDVEEEEKEQILLYHSEKLAIAFGILNLKAGRPILVTKNLRVCGDCHTAIKFMTLITKREITVRDANRFHHFKNGTCNCGDFW 785          

Query:  490 KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGA---YVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQL-SGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITP--RMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            K  Y  +L+AC   ++L   ++IHQH       +D  V   L  LY  C  +  A+ +F  +    V+ WN +I  ++ +G +D  I +   M   G  PN  T   VL   +   A+  G  +H  +    L  +V + T L+D Y+KC  +  A+R+F ++  ++ V W+AMI     Y +CD   +A+ L  +M   + I P   T+  +L    +   L  G+ +H Y ++  FD   +VG  +L MYAKC  +  A + FD M  ++ VS+SA+I G V +   KEAL +F  M L    DP   T+  VL AC+ L  L  G   H Y I  G   D  + N L+ MY+KCG I+   + FD M  +D +S++A++ G   +G    A+S F  M  +GI PD  T +G+L ACSH   +  G       S  + I      +  IC  ++D+  + G ++ A     +M    D+  W+A++    +H
Sbjct:    8 KNNYLHLLEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCD---DAVQLIMQM-QEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVASDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGSVLDILLGNTLLSMYAKCGVIDDAIRFFDEMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHG-----FCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMD-RHDIVSWNAMIIGYGIH 492          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            CI+SKSL +AKKIHQH LKNT+     S +L K+  LY++CNQV LA R+FDEIP PSVILWN +IRAYAWNGPF+ AI LY+ +L  GV+P KYTYPFVLKACSGL A+E G EIH HAK  GL SDV+VCTAL+D YAKCG L EAQ +F  M ++DVVAWNAMIAG SL+GL DD +Q+++QMQ+ G  PN+STIV VLPTV +A AL  GKA+HG+ +RRS    VV+GTGLLDMY+KCQC+ YAR+IFD + V+NEV WSAMIG YV  D M+EA+ LFD+M+L+  ++PTPVTLGS+LRAC KLTDLSRGR++HCY IK G  L+ ++GNT+LSMYAKCG+IDDA+RFFD MN KD+VS+SAI+SGCVQNG A  AL IF  MQLSG DPDL TM+GVLPACSHLAALQHG C H Y IV GF TDT ICN LIDMYSKCGKI+  R+VF+RM   DI+SWNAMI+GYGIHGLGM A+  FH +LA G+KPDD+TFI LLS+CSHSGLV EG+ WF+AMS DF+I PRMEH ICMVD+LGRAG + EAH FI+ MPFE DVR+WSALL+ACR+H NIELGEEVSKKIQ  G E TGN VLLSNIYSA GRWDDAA++RI QK  GLKK PGCSW+EINGI+H FVGGDQSH Q +QI+ KLEELLV+MKRLGY AE SFV QDVEEEEKE+ILLYHSEKLAIA+ IL+L+ G+PILVTKNLRVCGDCHAAIK +T+ITKREI VRD  RFHHFK+G CNC DFW
Sbjct:   18 CIQSKSLTEAKKIHQHFLKNTSNAD--SSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVXSDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGXVLDILLGNTLLSMYAKCGVIDDAIRFFDXMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHGFCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMDRHDIVSWNAMIIGYGIHGLGMEALGLFHDLLALGLKPDDITFICLLSSCSHSGLVMEGRLWFDAMSRDFSIVPRMEHCICMVDILGRAGLIDEAHHFIRNMPFEPDVRIWSALLSACRIHKNIELGEEVSKKIQSLGPESTGNFVLLSNIYSAAGRWDDAAHIRITQKDWGLKKIPGCSWIEINGIVHAFVGGDQSHLQLSQINRKLEELLVEMKRLGYQAECSFVFQDVEEEEKEQILLYHSEKLAIAFGILNLKAGRPILVTKNLRVCGDCHAAIKFMTVITKREITVRDANRFHHFKNGTCNCGDFW 785          

Query:  490 KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGA---YVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQL-SGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITP--RMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            K  Y  +L+AC   ++L   ++IHQH       +D  V   L  LY  C  +  A+ +F  +    V+ WN +I  ++ +G +D  I +   M   G  PN  T   VL   +   A+  G  +H  +    L  +V + T L+D Y+KC  +  A+R+F ++  ++ V W+AMI     Y +CD   +A+ L  +M   + I P   T+  +L    +   L  G+ +H Y ++  FD   +VG  +L MYAKC  +  A + FD M  ++ VS+SA+I G V +   KEAL +F  M L    DP   T+  VL AC+ L  L  G   H Y I  G   D  + N L+ MY+KCG I+   + FD M  +D +S++A++ G   +G    A+S F  M  +GI PD  T +G+L ACSH   +  G       S  + I      +  IC  ++D+  + G ++ A     +M    D+  W+A++    +H
Sbjct:    8 KNNYLHLLEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCD---DAVQLIMQM-QEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVXSDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGXVLDILLGNTLLSMYAKCGVIDDAIRFFDXMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHG-----FCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMD-RHDIVSWNAMIIGYGIH 492          

Query: 1069 MVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK 1767
            M LR E+    + L   L AC +   L+  +++H + +K+  + ++ V + +  +Y  C  +  A R FD++ +   + ++ II     NG    A+ ++H M   G  P+  T   VL ACS L A++ G   H+++ + G  +D  +C  L+D Y+KCG +   +++F  M  RD+++WNAMI G  ++GL   A+     M   GI P+  T +G+L     +  +  GK
Sbjct:    1 MPLRXEVKNNYLHL---LEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPTVGEAKALGHGK 230          

Query:  277 RLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLY--KDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            R+ D+     ++A  +I+ N++ LA  VFD+IP+PSV+LWN++IR YAW+GPF+++I+LY  +LQ GV PT +T+PF+LKACS LQAL+ GR IH HA  LGL+ D+YV TAL+ +YAKCG L +AQT+F  + +  +D+VAWNAMIA FS H L+  TI  + QMQ+AG +PN+ST+V++LPT+ QANAL QGKA+H + +R      VVL T LLDMY+KC  + YAR+IF+ ++ KN+VCWSAMIG YV+ DS+ +A+AL+D+M+    +NPTP TL ++LRAC +LTDL RG+++HC+ IKSG DL+T VGN+++SMYAKCGI+D+AV F D+M +KDTVSYSAIISGCVQNGYA++ALLIF  MQ SG  P L TM+ +LPACSHLAALQHG C H Y++V GF  DTSICN +IDMYSKCGKI   R++FDRM  RDIISWN MI+GYGIHGL + A+S F  + A G+KPDDVT I +LSACSHSGLVTEGK+WF++MS++FNI PRM HYICMVDLL RAG L EA+ FIQ+MPF  +VR+W ALLAACR H NIE+GE+VSKKIQ  G EGTGN VL+SNIYS+VGRWDDAAY+R  Q+  G KKSPGCSWVEI+G+IH F+GG QSHPQSA I++KL+ELLV MK+LGY A++SFVL DVEEEEKE+ILLYHSEK+AIA+ IL+  P   ILVTKNLR+C DCH+AIK ITL+T+REI VRD +RFHHFKDGICNC DFW
Sbjct:   36 RVSDSDAAATQLARYHISRNEIQLARHVFDQIPKPSVVLWNMMIRTYAWSGPFQQSIYLYLHMLQLGVTPTNFTFPFLLKACSSLQALQLGRLIHTHAHILGLSMDLYVSTALLHMYAKCGHLYQAQTLFNSISHQDRDIVAWNAMIAAFSFHALHAQTIHSVAQMQQAGVTPNSSTLVSILPTIGQANALHQGKAIHAYYIRNFFFDNVVLQTALLDMYAKCHLLFYARKIFNTVNKKNDVCWSAMIGGYVLHDSISDALALYDDMLCIYGLNPTPATLATMLRACAQLTDLKRGKKLHCHMIKSGMDLDTTVGNSLISMYAKCGIMDNAVGFLDEMIAKDTVSYSAIISGCVQNGYAEKALLIFRQMQSSGIAPYLETMIALLPACSHLAALQHGTCCHGYTVVRGFTNDTSICNAIIDMYSKCGKITISREIFDRMQNRDIISWNTMIIGYGIHGLCVEALSLFQELQALGLKPDDVTLIAVLSACSHSGLVTEGKYWFSSMSQNFNIKPRMAHYICMVDLLARAGNLDEAYTFIQRMPFVPNVRIWGALLAACRTHKNIEMGEQVSKKIQLLGPEGTGNFVLMSNIYSSVGRWDDAAYIRSIQRHHGYKKSPGCSWVEISGVIHVFIGGHQSHPQSASINKKLQELLVQMKKLGYRADSSFVLHDVEEEEKEQILLYHSEKVAIAFGILNTSPSSRILVTKNLRICVDCHSAIKFITLLTEREITVRDASRFHHFKDGICNCQDFW 785          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGK 855
            C +   L + KK+H H++K+   L  T  +   +  +Y  C  +D A    DE+     + ++ +I     NG  E+A+ ++  +  SG+ P   T   +L ACS L AL+ G   H +    G  +D  +C A+ID+Y+KCG +  ++ +F  M  +D+++WN MI G+ +HGL  + + +  ++Q  G  P+  T++AVL   + +  +++GK
Sbjct:  322 CAQLTDLKRGKKLHCHMIKSGMDLDTT--VGNSLISMYAKCGIMDNAVGFLDEMIAKDTVSYSAIISGCVQNGYAEKALLIFRQMQSSGIAPYLETMIALLPACSHLAALQHGTCCHGYTVVRGFTNDTSICNAIIDMYSKCGKITISREIFDRMQNRDIISWNTMIIGYGIHGLCVEALSLFQELQALGLKPDDVTLIAVLSACSHSGLVTEGK 534          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFL-----LEKVAHLYITCNQVDLASRVFDEIPQ--PSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLH-GLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAID-VKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKE--INPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGD-QSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +CI+SKSL + K IHQHLLK   R  +T+        EK+  LYI C+++ +A  VFD++P    +V+LWNLLIRAYAWNGP+E AI LYY +L  G+ P ++T+PFVLKACS L+    GREIH   K L L S+VYV TAL+D YAKCG L +A+ VF  M  +DVVAWN+MI+GFSLH G YD+  ++LVQMQ    SPN+STIV VLP VAQ N+L  GK +HGF +RR   G+VV+GTG+LD+Y KCQCI YARRIFD +  VKNEV WSAM+GAYV+CD MREA+ LF ++++ K+  I  + VTL +++R C  LTDLS G  +HCYAIKSGF L+ MVGNT+LSMYAKCGII+ A+RFF++M+ +D VS++AIISG VQNG ++E L +F  MQLSG +P+ AT+  VLPAC+HLA L +G+C H Y+I+ GF  DT ICN LIDMY+KCGKI+  R+VFDRM  R I+SWN MI+ YGIHG+G+ A+  F +M + G+KPDDVTFI L+SACSHSGLV EGK+WFNAM++DF I PRMEHY CMVDLL RAG   E H FI+KMP E DVRVW ALL+ACRV+ N+ELGE VSKKIQ  G E TGN VLLSN+YSAVGRWDDAA VR  QK QG +KSPGCSW+EI+G++H F+GG  +SHPQ  QI  KL+ELLV+MKRLGY AE+S+V QDVEEEEKER+LLYHSEKLAIA+ ILSL P K I+VTKNLRVCGDCH AIK I+L+TKR+I VRD +RFHHFKDGICNC DFW
Sbjct:   18 SCIQSKSLFRGKLIHQHLLKCLHRTHETNLTNFDVPFEKLVDLYIACSELKIARHVFDKMPHRPKNVVLWNLLIRAYAWNGPYEEAIDLYYKMLGYGITPNRFTFPFVLKACSALKEASEGREIHCDIKRLRLESNVYVSTALVDFYAKCGCLDDAKEVFDKMHKRDVVAWNSMISGFSLHEGSYDEVARLLVQMQN-DVSPNSSTIVGVLPAVAQVNSLRHGKEIHGFCVRRGFVGDVVVGTGILDVYGKCQCIDYARRIFDMMGIVKNEVTWSAMVGAYVVCDFMREALELFCQLLMLKDDVIVLSAVTLATVIRVCANLTDLSTGTCLHCYAIKSGFVLDLMVGNTLLSMYAKCGIINGAMRFFNEMDLRDAVSFTAIISGYVQNGNSEEGLRMFLEMQLSGINPEKATLASVLPACAHLAGLHYGSCSHCYAIICGFTADTMICNALIDMYAKCGKIDTARKVFDRMHKRGIVSWNTMIIAYGIHGIGLEALLLFDNMQSEGLKPDDVTFICLISACSHSGLVAEGKYWFNAMTQDFGIIPRMEHYACMVDLLSRAGLFKEVHSFIEKMPLEPDVRVWGALLSACRVYKNVELGEGVSKKIQKLGPESTGNFVLLSNMYSAVGRWDDAAQVRFTQKEQGFEKSPGCSWIEISGVVHTFLGGGYRSHPQLTQISNKLDELLVEMKRLGYQAESSYVFQDVEEEEKERVLLYHSEKLAIAFGILSLSPDKHIIVTKNLRVCGDCHTAIKFISLVTKRDITVRDASRFHHFKDGICNCGDFW 799          

Query:  340 VDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICN 2505
            V+ A  VF++IP+PSV+LWN++IRAYAWN PF ++IHLY+ +LQ GV PT +T+PFVLKACS LQA++ GR+IH HA  LGL +DVYV TAL+D+YAKCG L EAQT+F  M ++D+VAWNA+IAGFSLH L++ TI ++VQMQ+AG +PN+ST+V+VLPTV QANAL QGKA+H +S+R+  S +VV+ TGLLDMY+KC  ++YAR+IFD ++ KNE+CWSAMIG YVICDSMR+A+AL+D+MV    ++P P TL SILRAC KLTDL++G+ +HCY IKSG   +T VGN+++SMYAKCGIIDD++ F D+M +KD VSYSAIISGCVQNGYA++A+LIF  MQLSG DPD ATM+G+LPACSHLAALQHGAC H YS+                    CGKI+  RQVFDRM  RDI+SWN MI+GY IHGL + A S FH +  +G+K DDVT + +LSACSHSGLV EGK+WFN MS+D NI PRM HYICMVDLL RAG L EA+ FIQ MPF+ DVRVW+ALLAACR H NIE+GE+VSKKIQ  G EGTGN VL+SNIYS+VGRWDDAA +R  Q+ QG KKSPGCSW+EI+G IHGF+GGD+SHPQS  I+ KL+ELLV MK+LGY A++ FVL DVEEEEKE+ILLYHSEK+AIA+ IL+  P  PILVTKNLR+C DCH A+K +TLITKREI VRD +RFHHF++ ICN
Sbjct:    1 VEHARHVFEKIPKPSVVLWNMMIRAYAWNDPFLQSIHLYHRMLQLGVTPTNFTFPFVLKACSALQAIQVGRQIHGHALTLGLQTDVYVSTALLDMYAKCGDLFEAQTMFDIMTHRDLVAWNAIIAGFSLHVLHNQTIHLVVQMQQAGITPNSSTVVSVLPTVGQANALHQGKAIHAYSVRKIFSHDVVVATGLLDMYAKCHHLSYARKIFDTVNQKNEICWSAMIGGYVICDSMRDALALYDDMVYMHGLSPMPATLASILRACAKLTDLNKGKNLHCYMIKSGISSDTTVGNSLISMYAKCGIIDDSLGFLDEMITKDIVSYSAIISGCVQNGYAEKAILIFRQMQLSGTDPDSATMIGLLPACSHLAALQHGACCHGYSV--------------------CGKIHISRQVFDRMKKRDIVSWNTMIIGYAIHGLYIEAFSLFHELQESGLKLDDVTLVAVLSACSHSGLVVEGKYWFNTMSQDLNILPRMAHYICMVDLLARAGNLEEAYSFIQNMPFQPDVRVWNALLAACRTHKNIEMGEQVSKKIQMLGPEGTGNFVLMSNIYSSVGRWDDAAQIRSIQRHQGYKKSPGCSWIEISGAIHGFIGGDRSHPQSVSINNKLQELLVQMKKLGYHADSGFVLHDVEEEEKEQILLYHSEKIAIAFGILNTSPSNPILVTKNLRICVDCHTAVKFMTLITKREITVRDASRFHHFENEICN 702          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSL-------HGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVL---------IDMYSKCGKINRGRQVFDRMVTR-DIISWNAMIVGYGIH 1641
            C   +++   ++IH H L  T  L+   ++   +  +Y  C  +  A  +FD +    ++ WN +I  ++ +    + IHL   + Q+G+ P   T   VL       AL  G+ IH ++     + DV V T L+D+YAKC  L+ A+ +F  +  K+ + W+AMI G+ +         LYDD + M       G SP  +T+ ++L   A+   L++GK +H + ++  +S +  +G  L+ MY+KC  I  +    D +  K+ V +SA+I   V      +A+ +F +M L    +P   T+  +L AC+ L  L  G   H Y++                    CG I  + + FD+M  +D VS++ +I G   +G   EA  +FH +Q SG   D  T+V VL ACSH   +  G         + F T +   N+L         +D+ ++ G +         M  + D+  WNA++     H
Sbjct:   61 CSALQAIQVGRQIHGHAL--TLGLQTDVYVSTALLDMYAKCGDLFEAQTMFDIMTHRDLVAWNAIIAGFSLHVLHNQTIHLVVQMQQAGITPNSSTVVSVLPTVGQANALHQGKAIHAYSVRKIFSHDVVVATGLLDMYAKCHHLSYARKIFDTVNQKNEICWSAMIGGYVICDSMRDALALYDDMVYM------HGLSPMPATLASILRACAKLTDLNKGKNLHCYMIKSGISSDTTVGNSLISMYAKCGIIDDSLGFLDEMITKDIVSYSAIISGCVQNGYAEKAILIFRQMQL-SGTDPDSATMIGLLPACSHLAALQHGACCHGYSV--------------------CGKIHISRQVFDRMKKRDIVSWNTMIIGYAIHGLYIEAFSLFHELQESGLKLDDVTLVAVLSACSHSGLVVEGK--------YWFNTMSQDLNILPRMAHYICMVDLLARAGNLEEAYSFIQNMPFQPDVRVWNALLAACRTH 517          

Query:  187 HYHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQ-KAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSG---EVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            H   +ST  +R +  P     H+        +KD     +++   +I   Q+ LA +VFD IP P    +N LIRAY+W GPF  AI LY  +L   V P KYT+PFVLKACS L  L AGR IH HA A+GL +D++V TALIDLY +C     A  VF  M  +DVVAWNAM+AG++ HG+Y   I  L+ MQ + G  PNAST+V++LP +AQ  AL QG ++H + LR  L     +V++GT LLDMY+KC+ + YA R+F  + V+NEV WSA+IG +V+CD M EA  LF +M++      +  ++ S LR C  L DL  G ++H    KSG   +   GN++LSMYAK G+I++A   FD++  KDT+SY A++SG VQNG A+EA L+F  MQ     PD+ATMV ++PACSHLAALQHG C H   I+ G   +TSICN LIDMY+KCG+I+  RQVFD+M  RDI+SWN MI GYGIHGLG  A + F  M   G +PDDVTFI L++ACSHSGLVTEGKHWF+ M+  + I PRMEHYICMVDLL R GFL EA+ FIQ MP +ADVRVW ALL ACR+H NI+LG++VS+ IQ  G EGTGN VLLSNI+SA GR+D+AA VRI QK +G KKSPGCSW+EING +H FVGGDQSHP S  I+ +L+ +L+D+K+LGY A+ SFVLQD+EEEEKE+ LLYHSEKLAIA+ +LSL   K I VTKNLRVCGDCH AIK +TL+  R IIVRD  RFHHFK+G C+C DFW
Sbjct:    7 HLRPFSTAAVRLRRPPSGSISHE--------VKDNKEWQQELEQ-HIARGQLALARQVFDRIPAPDARAYNALIRAYSWRGPFHAAIDLYRSMLYFRVPPNKYTFPFVLKACSALADLCAGRTIHAHAAAVGLHTDLFVSTALIDLYIRCARFGPAANVFAKMPMRDVVAWNAMLAGYANHGMYHHAIAHLLDMQDRGGLRPNASTLVSLLPLLAQHGALFQGTSVHAYCLRAYLDQNEEQVLIGTALLDMYAKCKHLVYACRVFHGMTVRNEVTWSALIGGFVLCDRMTEAFNLFKDMLVEGMCFLSATSVASALRVCASLADLRMGTQLHALLAKSGIHADLTAGNSLLSMYAKAGLINEATMLFDEIAIKDTISYGALLSGYVQNGKAEEAFLVFKKMQACNVQPDIATMVSLIPACSHLAALQHGRCSHGSVIIRGLALETSICNSLIDMYAKCGRIDLSRQVFDKMPARDIVSWNTMIAGYGIHGLGKEATTLFLSMKNQGFEPDDVTFICLIAACSHSGLVTEGKHWFDTMTHKYGILPRMEHYICMVDLLARGGFLDEAYQFIQSMPLKADVRVWGALLGACRIHKNIDLGKQVSRMIQKLGPEGTGNFVLLSNIFSAAGRFDEAAEVRIIQKVKGFKKSPGCSWIEINGSLHAFVGGDQSHPCSPDIYHELDNILIDIKKLGYQADTSFVLQDLEEEEKEKALLYHSEKLAIAFGVLSLNEDKTIFVTKNLRVCGDCHTAIKYMTLVRNRTIIVRDANRFHHFKNGQCSCGDFW 779          

Query:  325 ITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGV-KPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGE----VVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            + C  + LA  +FD+IP P +  +N LIRAY+  GP   A+ LY  L +  + +P  YT+PFVLKACS L  L + R +H HA   GL +D++V TAL+D+YAKC     A TVFR M  +DVVAWNAM+AG++LHG Y DTI  L+ MQ    +PNAST+VA+LP +AQ  ALSQG+A+H +S+R     +    V++GT LLDMY+KC  + YA R+F+A+ V+NEV WSA++G +V+C  M EA +LF +M+ +     +P ++ S LRAC  L+DL  G+++H    KSG   +   GN++LSMYAK G+ID A   FD+M  KDTVSYSA++SG VQNG A EA  +F  MQ     PD+ATMV ++PACSHLAALQHG CGH   IV G  ++TSICN LIDMY+KCG+I+  RQ+FD M  RDI+SWN MI GYGIHGLG  A + F  M     +PDDVTFI L+SACSHSGLVTEGK WF+ M+  + ITPRMEHYI MVDLL R GFL EA+ FIQ MP +ADVRVW ALL ACRVH NI+LG++VS  IQ  G EGTGN VLLSNI+SA GR+D+AA VRI QK QG KKSPGCSW+EING +H F+GGD+SH QS++I+++L+ +LVD+ +LGY A+ SFVLQDVEEEEKE+ LLYHSEKLAIA+ +L+L   K I VTKNLRVCGDCH  IK +TL+ KR IIVRD  RFHHFK+G C+C DFW
Sbjct:    1 MACGDLSLARHLFDQIPAPGIHDYNALIRAYSLRGP-ALALRLYRSLRRRRLPQPNNYTFPFVLKACSALLDLRSARAVHCHAARAGLHADLFVSTALVDVYAKCASFRHAATVFRRMPARDVVAWNAMLAGYALHGKYSDTIACLLLMQD-DHAPNASTLVALLPLLAQHGALSQGRAVHAYSVRACSLHDHKDGVLVGTALLDMYAKCGHLVYASRVFEAMAVRNEVTWSALVGGFVLCGRMLEAFSLFKDMLAQGLCFLSPTSVASALRACANLSDLCLGKQLHALLAKSGLHTDLTAGNSLLSMYAKAGLIDQATTLFDQMVVKDTVSYSALVSGYVQNGKADEAFRVFRKMQACNVQPDVATMVSLIPACSHLAALQHGKCGHGSVIVRGIASETSICNALIDMYAKCGRIDLSRQIFDVMPARDIVSWNTMIAGYGIHGLGKEATALFLDMKHQACEPDDVTFICLISACSHSGLVTEGKRWFHMMAHKYGITPRMEHYIGMVDLLARGGFLDEAYQFIQGMPLKADVRVWGALLGACRVHKNIDLGKQVSSMIQQLGPEGTGNFVLLSNIFSAAGRFDEAAEVRIIQKEQGFKKSPGCSWIEINGSLHAFIGGDRSHAQSSEIYQELDNILVDINKLGYRADTSFVLQDVEEEEKEKALLYHSEKLAIAFGVLTLSEDKTIFVTKNLRVCGDCHTVIKYMTLVRKRAIIVRDANRFHHFKNGQCSCGDFW 735          

Query:  226 SLPQAKKIHQHLLKNTTRL--KDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSG---VKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRR-VHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGC 1329
            +L Q + +H + ++  +    KD   +   +  +Y  C  +  ASRVF+ +   + + W+ L+  +   G    A  L+ D+L  G   + PT  +    L+AC+ L  L  G+++H      GL +D+    +L+ +YAK G + +A T+F  M+ KD V+++A+++G+  +G  D+  ++  +MQ     P+ +T+V+++P  +   AL  GK  HG  + R ++ E  +   L+DMY+KC  I  +R+IFD +  ++ V W+ MI  Y I    +EA ALF +M   +   P  VT   ++ AC+    ++ G+R  H  A K G          ++ + A+ G +D+A +F   M  K D   + A++  C
Sbjct:  171 ALSQGRAVHAYSVRACSLHDHKDGVLVGTALLDMYAKCGHLVYASRVFEAMAVRNEVTWSALVGGFVLCGRMLEAFSLFKDMLAQGLCFLSPT--SVASALRACANLSDLCLGKQLHALLAKSGLHTDLTAGNSLLSMYAKAGLIDQATTLFDQMVVKDTVSYSALVSGYVQNGKADEAFRVFRKMQACNVQPDVATMVSLIPACSHLAALQHGKCGHGSVIVRGIASETSICNALIDMYAKCGRIDLSRQIFDVMPARDIVSWNTMIAGYGIHGLGKEATALFLDM-KHQACEPDDVTFICLISACSHSGLVTEGKRWFHMMAHKYGITPRMEHYIGMVDLLARGGFLDEAYQFIQGMPLKADVRVWGALLGAC 542          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKA-MHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEV-CWSAMIGA 1020
            C     L   K++H  L K+      T+     +  +Y     +D A+ +FD++     + ++ L+  Y  NG  + A  ++  +    V+P   T   ++ ACS L AL+ G+  H      G+AS+  +C ALID+YAKCG +  ++ +F  M  +D+V+WN MIAG+ +HGL  +   + + M+     P+  T + ++   + +  +++GK   H  + +  ++  +    G++D+ ++   +  A +    + +K +V  W A++GA
Sbjct:  272 CANLSDLCLGKQLHALLAKSGLHTDLTAG--NSLLSMYAKAGLIDQATTLFDQMVVKDTVSYSALVSGYVQNGKADEAFRVFRKMQACNVQPDVATMVSLIPACSHLAALQHGKCGHGSVIVRGIASETSICNALIDMYAKCGRIDLSRQIFDVMPARDIVSWNTMIAGYGIHGLGKEATALFLDMKHQACEPDDVTFICLISACSHSGLVTEGKRWFHMMAHKYGITPRMEHYIGMVDLLARGGFLDEAYQFIQGMPLKADVRVWGALLGA 541          

Query:  292 SFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERA--IHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLV--QMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR----------SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            S LL+   H  I    +  A  +FD+IP P V  +N LIRAY+ + P   A  +HLY  +L+  V P  YT+PF LKACS L     GR IH+HA   GL +D++V TAL+D+Y KC  L +A  +F  M  +D+VAWNAM+AG++ HG+Y   +  L+  QMQ     PNAST+VA+LP +AQ  AL+QG ++H + +R            L+  V+LGT LLDMY+KC  + YARR+FDA+  +NEV WSA+IG +V+C  M +A  LF  M+ +     +P ++ S LRAC  L  L  G ++H    KSG   +   GN++LSMYAK G+ID A+  FD+M  KDTVSYSA++SG VQNG A+EA L+F  MQ    +PD ATMV ++PACSHLAALQHG C H   I+ G  ++TSICN LIDMY+KCG+I+  RQVF+ M +RDI+SWN MI GYGIHGLG  A + F  M   G  PD VTFI LLSACSHSGLV EGKHWF+ M   + +TPRMEHYICMVDLL R GFL EA+ FIQ MP  ADVRVW ALL ACRV+ NI+LG++VS+ IQ  G EGTGN VLLSNIYSA GR+D+AA VRI QK QG KKSPGCSW+EING +H FVGGDQSHPQS +I+ +L+ +LV +K+LGY  + SFVLQD+EEEEKE+ L+ HSEKLAIAY ILSL   K I VTKNLRVCGDCH  IK I+L+ +R IIVRD  RFHHFK+G C+C DFW
Sbjct:   59 SLLLQLQDH--IASGHLSRAHHLFDQIPSPDVRTYNDLIRAYSSSSPTAAADGLHLYRRMLRHRVAPNNYTFPFALKACSALADHHCGRAIHRHAIHAGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGACRVYKNIDLGKKVSRMIQELGPEGTGNFVLLSNIYSAAGRFDEAAEVRIIQKVQGFKKSPGCSWIEINGSLHAFVGGDQSHPQSPEIYRELDNILVGIKKLGYQPDTSFVLQDLEEEEKEKALICHSEKLAIAYGILSLSEDKTIFVTKNLRVCGDCHTVIKHISLVKRRAIIVRDANRFHHFKNGQCSCGDFW 813          

Query:  226 SLPQAKKIHQHLLK--------NTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSG---VKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTI--LSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGC 1329
            +L Q   +H + ++        + ++L D   L   +  +Y  C  +  A RVFD +P  + + W+ LI  +       +A  L+  +L  G   + PT  +    L+AC+ L  L  G ++H      G+ +D+    +L+ +YAK G + +A  +F  M  KD V+++A+++G+  +G  ++   +  +MQ     P+A+T+V+++P  +   AL  G+  HG  + R L+ E  +   L+DMY+KC  I  +R++F+ +  ++ V W+ MI  Y I    +EA ALF EM       P  VT   +L AC+    +  G+    + +  G+ L   + + I  + + ++ G +D+A  F   M  + D   + A++  C
Sbjct:  243 ALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPT--SIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEM-NNLGFPPDGVTFICLLSACSHSGLVIEGKH-WFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGAC 620          

Query:  292 SFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERA--IHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLV--QMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGE----------VVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            S LL+   H  I    +  A  +FD+IP P V  +N LIRAY+ + P   A  +HLY  +L+  V P  YT+PF LKACS L     GR IH+HA   GL +D++V TAL+D+Y KC  L +A  +F  M  +D+VAWNAM+AG++ HG+Y   +  L+  QMQ     PNAST+VA+LP +AQ  AL+QG ++H + +R  L             V+LGT LLDMY+KC  + YARR+FDA+  +NEV WSA+IG +V+C  M +A  LF  M+ +     +P ++ S LRAC  L  L  G ++H    KSG   +   GN++LSMYAK G+ID A+  FD+M  KDTVSYSA++SG VQNG A+EA L+F  MQ    +PD ATMV ++PACSHLAALQHG C H   I+ G  ++TSICN LIDMY+KCG+I+  RQVF+ M +RDI+SWN MI GYGIHGLG  A + F  M   G  PD VTFI LLSACSHSGLV EGKHWF+ M   + +TPRMEHYICMVDLL R GFL EA+ FIQ MP  ADVRVW ALL ACRV+ NI+LG++VS+ IQ  G EGTGN VLLSNIYSA GR+D+AA VRI QK QG KKSPGCSW+EING +H FVGGDQSHPQS +I+ +L+ +LV +K+LGY  + SFVLQD+EEEEKE+ L+ HSEKLAIAY ILSL   K I VTKNLRVCGDCH  IK I+L+ +R IIVRD  RFHHFK+G C+C DFW
Sbjct:   59 SLLLQLQDH--IASGHLSRAHHLFDQIPSPDVRTYNDLIRAYSSSSPTAAADGLHLYRRMLRHRVAPNNYTFPFALKACSALADHHCGRAIHRHAIHAGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYRIRACLHSNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMRHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGACRVYKNIDLGKKVSRMIQELGPEGTGNFVLLSNIYSAAGRFDEAAEVRIIQKVQGFKKSPGCSWIEINGSLHAFVGGDQSHPQSPEIYRELDNILVGIKKLGYQPDTSFVLQDLEEEEKEKALICHSEKLAIAYGILSLSEDKTIFVTKNLRVCGDCHTVIKHISLLKRRAIIVRDANRFHHFKNGQCSCGDFW 813          

Query:  226 SLPQAKKIHQHLLK--------NTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSG---VKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTI--LSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGC 1329
            +L Q   +H + ++        + ++L D   L   +  +Y  C  +  A RVFD +P  + + W+ LI  +       +A  L+  +L  G   + PT  +    L+AC+ L  L  G ++H      G+ +D+    +L+ +YAK G + +A  +F  M  KD V+++A+++G+  +G  ++   +  +MQ     P+A+T+V+++P  +   AL  G+  HG  + R L+ E  +   L+DMY+KC  I  +R++F+ +  ++ V W+ MI  Y I    +EA ALF EM       P  VT   +L AC+    +  G+    + ++ G+ L   + + I  + + ++ G +D+A  F   M  + D   + A++  C
Sbjct:  243 ALAQGTSVHAYRIRACLHSNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPT--SIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEM-NNLGFPPDGVTFICLLSACSHSGLVIEGKH-WFHVMRHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGAC 620          

Query:  292 SFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERA--IHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLV--QMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR----------SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            S LL+   H  I    +  A  +FD+IP P V  +N LIRAY+ + P   A  +HLY  +L+  V P  YT+PF LKACS L     GR IH+HA   GL +D++V TAL+D+Y KC  L +A  +F  M  +D+VAWNAM+AG++ HG+Y   +  L+  QMQ     PNAST+VA+LP +AQ  AL+QG ++H + +R            L+  V+LGT LLDMY+KC  + YARR+FDA+  +NEV WSA+IG +V+C  M +A  LF  M+ +     +P ++ S LRAC  L  L  G ++H    KSG   +   GN++LSMYAK G+ID A+  FD+M  KDTVSYSA++SG VQNG A+EA L+F  MQ    +PD ATMV ++PACSHLAALQHG C H   I+ G  ++TSICN LIDMY+KCG+I+  RQVF+ M +RDI+SWN MI GYGIHGLG  A + F  M   G  PD VTFI LLSACSHSGLV EGKHWF+ M   + +TPRMEHYICMVDLL R GFL EA+ FIQ MP  ADVRVW ALL ACRV+ NI+LG++VS+ IQ  G EGTGN VLLSNIYSA GR+D+AA VRI QK QG KKSPGCSW+EING +H FVGGDQSH QS +I+ +L+ +LV +K+LGY  + SFVLQD+EEEEKE+ L+ HSEKLAIAY ILSL   K I VTKNLRVCGDCH  IK I+L+ +R IIVRD  RFHHFK+G C+C DFW
Sbjct:   59 SLLLQLQDH--IASGHLSRAHHLFDQIPSPDVRTYNDLIRAYS-SSPTAAADGLHLYRRMLRHRVAPNNYTFPFALKACSALVDHHCGRAIHRHAIHAGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGACRVYKNIDLGKKVSRMIQELGPEGTGNFVLLSNIYSAAGRFDEAAEVRIIQKVQGFKKSPGCSWIEINGSLHAFVGGDQSHLQSPEIYRELDNILVGIKKLGYQPDTSFVLQDLEEEEKEKALICHSEKLAIAYGILSLSEDKTIFVTKNLRVCGDCHTVIKHISLLKRRAIIVRDANRFHHFKNGQCSCGDFW 812          

Query:  226 SLPQAKKIHQHLLK--------NTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSG---VKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTI--LSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGC 1329
            +L Q   +H + ++        + ++L D   L   +  +Y  C  +  A RVFD +P  + + W+ LI  +       +A  L+  +L  G   + PT  +    L+AC+ L  L  G ++H      G+ +D+    +L+ +YAK G + +A  +F  M  KD V+++A+++G+  +G  ++   +  +MQ     P+A+T+V+++P  +   AL  G+  HG  + R L+ E  +   L+DMY+KC  I  +R++F+ +  ++ V W+ MI  Y I    +EA ALF EM       P  VT   +L AC+    +  G+    + +  G+ L   + + I  + + ++ G +D+A  F   M  + D   + A++  C
Sbjct:  242 ALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPT--SIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEM-NNLGFPPDGVTFICLLSACSHSGLVIEGKH-WFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGAC 619          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSV--ILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKA-GTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINP-TPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSE-DFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEI 2139
            TCIRS++L   + IHQHLLK +  L  ++ L+  +  LY +CN+V+LA  VFDEIP P +  I W+L+IRAYA N   E+A+ LYY +L SGV+PTKYTYPFVLKAC+GL+A++ G+ IH H      A+D+YVCTAL+D YAKCG L  A  VF  M  +D+VAWNAMI+GFSLH    D I + + M++  G SPN STIV + P + +A AL +GKA+HG+  R   S ++V+ TG+LD+Y+K +CI YARR+FD    KNEV WSAMIG YV  + ++EA  +F +M++   +   TPV +G IL  C +  DLS GR VHCYA+K+GF L+  V NTI+S YAK G + DA R F ++  KD +SY+++I+GCV N   +E+  +FH M+ SG  PD+ T++GVL ACSHLAAL HG+  H Y +VHG+  +TSICN L+DMY+KCGK++  ++VFD M  RDI+SWN M+ G+GIHGLG  A+S F+ M   G+ PD+VT + +LSACSHSGLV EGK  FN+MS  DFN+ PR++HY CM DLL RAG+L EA+ F+ KMPFE D+RV   LL+AC  + N ELG EVSKK+Q  G E T +LVLLSN YSA  RW+DAA +R+ QK +GL K+PG SWV++
Sbjct:    8 TCIRSRNLVLGQVIHQHLLKRSLTLSSSTVLVN-LTRLYASCNEVELARHVFDEIPHPRINPIAWDLMIRAYASNDFAEKALDLYYKMLNSGVRPTKYTYPFVLKACAGLRAIDDGKLIHSHVNCSDFATDMYVCTALVDFYAKCGELEMAIKVFDEMPKRDMVAWNAMISGFSLHCCLTDVIGLFLDMRRIDGLSPNLSTIVGMFPALGRAGALREGKAVHGYCTRMGFSNDLVVKTGILDVYAKSKCIIYARRVFDLDFKKNEVTWSAMIGGYVENEMIKEAGEVFFQMLVNDNVAMVTPVAIGLILMGCARFGDLSGGRCVHCYAVKAGFILDLTVQNTIISFYAKYGSLCDAFRQFSEIGLKDVISYNSLITGCVVNCRPEESFRLFHEMRTSGIRPDITTLLGVLTACSHLAALGHGSSCHGYCVVHGYAVNTSICNALMDMYTKCGKLDVAKRVFDTMHKRDIVSWNTMLFGFGIHGLGKEALSLFNSMQETGVNPDEVTLLAILSACSHSGLVDEGKQLFNSMSRGDFNVIPRIDHYNCMTDLLARAGYLDEAYDFVNKMPFEPDIRVLGTLLSACWTYKNAELGNEVSKKMQSLG-ETTESLVLLSNTYSAAERWEDAARIRMIQKKRGLLKTPGYSWVDV 654          

Query:  217 RSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            R  SL + ++I   + KN   L    F   K+  L+     VD A+RVF+ I     +L++ +++ +A     ++A+  +  +    V+P  Y + ++LK C     L  G+EIH      G + D++  T L ++YAKC  + EA+ VF  M  +D+V+WN ++AG+S +G+    ++M+  M +    P+  TIV+VLP V+    +S GK +HG+++R      V + T L+DMY+KC  +  AR++FD +  +N V W++MI AYV  ++ +EAM +F +M L + + PT V++   L AC  L DL RGR +H  +++ G D N  V N+++SMY KC  +D A   F K+ S+  VS++A+I G  QNG   +AL  F  M+     PD  T V V+ A + L+   H    H   +      +  +   L+DMY+KCG I   R +FD M  R + +WNAMI GYG HG G AA+  F  M    IKP+ VTF+ ++SACSHSGLV  G   F  M E+++I   M+HY  MVDLLGRAG L EA  FI +MP +  V V+ A+L AC++H N+   E+ ++++     +  G  VLL+NIY A   W+    VR+    QGL+K+PGCS VEI   +H F  G  +HP S +I+  LE+L+  +K  GY  + + VL  VE + KE++L  HSEKLAI++ +L+   G  I V KNLRVC DCH A K I+L+T REI+VRD+ RFHHFK+G C+C D+W
Sbjct:   46 RCSSLKELRQILPLVFKNG--LYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKM-LDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSKKIYAFLEKLICHIKEAGYVPDTNLVL-GVENDVKEQLLSTHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIVVRDMQRFHHFKNGACSCGDYW 809          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHM-QLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            C  SKSL   K++   +  N   +   S L  K++ +Y  C  +  ASRVFDE+     + WN+L+   A +G F  +I L+  ++ SGV+   YT+  V K+ S L+++  G ++H      G      V  +L+  Y K   +  A+ VF  M  +DV++WN++I G+  +GL +  + + VQM  +G   + +TIV+V    A +  +S G+A+H   ++   S E      LLDMYSKC  +  A+ +F  +  ++ V +++MI  Y       EA+ LF+EM   + I+P   T+ ++L  C +   L  G+RVH +  ++    +  V N ++ MYAKCG + +A   F +M  KD +S++ II G  +N YA EAL +F+ + +   F PD  T+  VLPAC+ L+A   G   H Y + +G+ +D  + N L+DMY+KCG +     +FD + ++D++SW  MI GYG+HG G  AI+ F+ M  AGI+ D+++F+ LL ACSHSGLV EG  +FN M  +  I P +EHY C+VD+L R G L +A+ FI+ MP   D  +W ALL  CR+H++++L E+V++K+     E TG  VL++NIY+   +W+    +R +   +GL+K+PGCSW+EI G ++ FV GD S+P++  I   L ++   M   GY     + L D EE EKE  L  HSEKLA+A  I+S   GK I VTKNLRVCGDCH   K ++ +T+REI++RD  RFH FKDG C+C  FW
Sbjct:  104 CADSKSLKDGKEVDNFIRGNGFVID--SNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEME-EEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDRHVANSLVDMYAKCGALLLAHMLFDDIASKDLVSWTVMIAGYGMHGFGKEAIALFNQMRQAGIEADEISFVSLLYACSHSGLVDEGWRFFNIMRHECKIEPTVEHYACIVDMLARTGDLIKAYRFIENMPIPPDATIWGALLCGCRIHHDVKLAEKVAEKVFELEPENTGYYVLMANIYAEAEKWEQVKRLRKRIGQRGLRKNPGCSWIEIKGRVNIFVAGDSSNPETENIEAFLRKVRARMIEEGYSPLTKYALIDAEEMEKEEALCGHSEKLAMALGIISSGHGKIIRVTKNLRVCGDCHEMAKFMSKLTRREIVLRDSNRFHQFKDGHCSCRGFW 871          

Query:  397 NLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHML-AAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYI-CMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            N  +R +  +G  E A+ L     +  + P   T   VL+ C+  ++L+ G+E+    +  G   D  + + L  +Y  CG L EA  VF  +  +  + WN ++   +  G +  +I +  +M  +G   ++ T   V  + +   ++  G+ +HGF L+        +G  L+  Y K Q +  AR++FD +  ++ + W+++I  YV      + +++F +M++   I     T+ S+   C     +S GR VH   +K+ F       NT+L MY+KCG +D A   F +M+ +  VSY+++I+G  + G A EA+ +F  M+  G  PD+ T+  VL  C+    L  G   H +   +  G D  + N L+DMY+KCG +     VF  M  +DIISWN +I GY  +     A+S F+ +L      PD+ T   +L AC+      +G+     +  +   + R  H    +VD+  + G L  AH+    +    D+  W+ ++A   +H
Sbjct:   65 NTQLRRFCESGNLENAVKLLCVSGKWDIDPR--TLCSVLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLV-SGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDR--HVANSLVDMYAKCGALLLAHMLFDDIA-SKDLVSWTVMIAGYGMH 578          

Query:  241 KKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGL---QALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR-SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQ-----------LSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEAD-VRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            K+IH H+ K    + D+  +   + +LY  C       +VFD I + + + WN LI +      +E A+  +  +L   V+P+ +T   V+ ACS L   + L  G+++H +    G  +  ++   L+ +Y K G LA ++ +      +D+V WN +++    +    + ++ L +M   G  P+  TI +VLP  +    L  GK +H ++L+  SL     +G+ L+DMY  C+ +   RR+FD +  +    W+AMI  Y   +  +EA+ LF  M     +     T+  ++ AC +    SR   +H + +K G D +  V NT++ MY++ G ID A+R F KM  +D V+++ +I+G V + + ++ALL+ H MQ                P+  T++ +LP+C+ L+AL  G   HAY+I +   TD ++ + L+DMY+KCG +   R+VFD++  +++I+WN +I+ YG+HG G  AI     M+  G+KP++VTFI + +ACSHSG+V EG   F  M  D+ + P  +HY C+VDLLGRAG + EA+  +  MP + +    WS+LL A R+HNN+E+GE  ++ +         + VLL+NIYS+ G WD A  VR   K QG++K PGCSW+E    +H FV GD SHPQS ++   LE L   M++ GY  + S VL +VEE+EKE +L  HSEKLAIA+ IL+  PG  I V KNLRVC DCH A K I+ I  REII+RD+ RFH FK+G C+C D+W
Sbjct:  117 KQIHAHVYKFGYGV-DSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNS-FIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYLETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:  220 SKSLPQAKKIHQHLLKNT--TRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASD-VYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVL---PTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSG-FDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLS-GFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHM-----------LAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSA 2049
            S+ LP ++  H +LL+ T  +  +D +  +     ++I+ ++              S   W  L+R+   +     A+  Y D++  G+KP  Y +P +LKA + LQ +E G++IH H    G   D V V   L++LY KCG       VF  +  ++ V+WN++I+       ++  ++    M      P++ T+V+V+     +     L  GK +H + LR+      ++ T L+ MY K   +A ++ +  +   ++ V W+ ++ +    + + EA+    EMVL + + P   T+ S+L AC+ L  L  G+ +H YA+K+G  D N+ VG+ ++ MY  C  +    R FD M  +    ++A+I+G  QN + KEALL+F  M+ S G   +  TM GV+PAC    A       H + +  G   D  + N L+DMYS+ GKI+   ++F +M  RD+++WN MI GY        A+   H M               +KP+ +T + +L +C+    + +GK   +A +   N+   +     +VD+  + G L  +     ++P + +V  W+ ++ A  +H N +   ++ + +  +G++   N V   ++++A
Sbjct:   19 SQLLPFSRHKHPYLLRATPTSATEDVASAVSGAPSIFISQSR--------------SPEWWIDLLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNSFIINT-LVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVL-EGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKE-IHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIP-QKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVK--PNEVTFISVFAA 627          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAK---ALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML--YKDVVAWNAMIAGFSLHG---LYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANAL 843
            +C    +L + K+IH + +KN   L     +   +  +Y  C  + ++ +VFD+IPQ +VI WN++I AY  +G  + AI L   ++  GVKP + T+  V  ACS    ++ G  I    K    +  +SD Y C  ++DL  + G + EA  +   M   +    AW++++    +H    + +   Q L+Q++     PN ++   +L  +  +  L
Sbjct:  526 SCAALSALAKGKEIHAYAIKN--NLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYAC--VVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLE-----PNVASHYVLLANIYSSAGL 736          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPS-VILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHA-KALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKR-LGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            C + + +    ++H  L+K       T F++  +  +Y   + +  A R+FD   +    +LWN ++ +Y+ +G     + L+ ++  +G  P  YT    L AC G    + G+EIH    K+   +S++YVC ALI +Y +CG + +A+ + R M   DVV WN++I G+  + +Y + ++    M  AG   +  ++ +++    + + L  G  +H + ++      + +G  L+DMYSKC    Y  R F  +  K+ + W+ +I  Y   D   EA+ LF + V +K +    + LGSILRA + L  +   + +HC+ ++ G  L+T++ N ++ +Y KC  +  A R F+ +  KD VS++++IS    NG   EA+ +F  M  +G   D   ++ +L A + L+AL  G   H Y +  GF  + SI   ++DMY+ CG +   + VFDR+  + ++ + +MI  YG+HG G AA+  F  M    + PD ++F+ LL ACSH+GL+ EG+ +   M  ++ + P  EHY+C+VD+LGRA  + EA  F++ M  E    VW ALLAACR H+  E+GE  ++++     +  GNLVL+SN+++  GRW+D   VR K K  G++K PGCSW+E++G +H F   D+SHP+S +I+EKL E+   ++R +GY A+  FVL +V+E EK ++L  HSE++AIAY +L       + +TKNLRVC DCH   K+++ + +R+I++RD  RFHHF+ G+C+C D W
Sbjct:  192 CAKLRDIRSGSELHSLLVK--LGYHSTGFIVNALVSMYAKNDDLSAARRLFDGFQEKGDAVLWNSILSSYSTSGKSLETLELFREMHMTGPAPNSYTIVSALTACDGFSYAKLGKEIHASVLKSSTHSSELYVCNALIAMYTRCGKMPQAERILRQMNNADVVTWNSLIKGYVQNLMYKEALEFFSDMIAAGHKSDEVSMTSIIAASGRLSNLLAGMELHAYVIKHGWDSNLQVGNTLIDMYSKCNLTCYMGRAFLRMHDKDLISWTTVIAGYAQNDCHVEALELFRD-VAKKRMEIDEMILGSILRASSVLKSMLIVKEIHCHILRKGL-LDTVIQNELVDVYGKCRNMGYATRVFESIKGKDVVSWTSMISSSALNGNESEAVELFRRMVETGLSADSVALLCILSAAASLSALNKGREIHCYLLRKGFCLEGSIAVAVVDMYACCGDLQSAKAVFDRIERKGLLQYTSMINAYGMHGCGKAAVELFDKMRHENVSPDHISFLALLYACSHAGLLDEGRGFLKIMEHEYELEPWPEHYVCLVDMLGRANCVVEAFEFVKMMKTEPTAEVWCALLAACRSHSEKEIGEIAAQRLLELEPKNPGNLVLVSNVFAEQGRWNDVEKVRAKMKASGMEKHPGCSWIEMDGKVHKFTARDKSHPESKEIYEKLSEVTRKLEREVGYVADTKFVLHNVDEGEKVQMLHGHSERIAIAYGLLRTPDRACLRITKNLRVCRDCHTFCKLVSKLFRRDIVMRDANRFHHFESGLCSCGDSW 960          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYK-DVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSL-SGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK 1767
            C + +++ Q +++H  + K      +  FL  K+  +Y  C  +D A +VFDE+P  +   WN +I AY  NG    A+ LY+++   GV     ++P +LKAC+ L+ + +G E+H     LG  S  ++  AL+ +YAK   L+ A+ +F G   K D V WN++++ +S  G   +T+++  +M   G +PN+ TIV+ L      +    GK +H   L+ S  S E+ +   L+ MY++C  +  A RI   ++  + V W+++I  YV     +EA+  F +M+         V++ SI+ A  +L++L  G  +H Y IK G+D N  VGNT++ MY+KC +     R F +M+ KD +S++ +I+G  QN    EAL +F  +     + D   +  +L A S L ++      H + +  G   DT I N L+D+Y KC  +    +VF+ +  +D++SW +MI    ++G    A+  F  M+  G+  D V  + +LSA +    + +G+
Sbjct:   90 CGKRRAVSQGRQLHSRIFKTFPSF-ELDFLAGKLVFMYGKCGSLDDAEKVFDEMPDRTAFAWNTMIGAYVSNGEPASALALYWNMRVEGVPLGLSSFPALLKACAKLRDIRSGSELHSLLVKLGYHSTGFIVNALVSMYAKNDDLSAARRLFDGFQEKGDAVLWNSILSSYSTSGKSLETLELFREMHMTGPAPNSYTIVSALTACDGFSYAKLGKEIHASVLKSSTHSSELYVCNALIAMYTRCGKMPQAERILRQMNNADVVTWNSLIKGYVQNLMYKEALEFFSDMIAAGH-KSDEVSMTSIIAASGRLSNLLAGMELHAYVIKHGWDSNLQVGNTLIDMYSKCNLTCYMGRAFLRMHDKDLISWTTVIAGYAQNDCHVEALELFRDVAKKRMEIDEMILGSILRASSVLKSMLIVKEIHCHILRKGL-LDTVIQNELVDVYGKCRNMGYATRVFESIKGKDVVSWTSMISSSALNGNESEAVELFRRMVETGLSADSVALLCILSAAASLSALNKGR 607          

Query: 1090 NPTPV-TLGSILRACTKLTDLSRGRRVHCYAIKS--GFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTR-DIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALL 1932
            N +PV     +L  C K   +S+GR++H    K+   F+L+ + G  +  MY KCG +DDA + FD+M  +   +++ +I   V NG    AL ++ +M++ G    L++   +L AC+ L  ++ G+  H+  +  G+ +   I N L+ MY+K   ++  R++FD    + D + WN+++  Y   G  +  +  F  M   G  P+  T +  L+AC        GK    ++ +  + T   E Y+C  ++ +  R G + +A   +++M   ADV  W++L+
Sbjct:   76 NNSPVEAFAYVLELCGKRRAVSQGRQLHSRIFKTFPSFELDFLAGKLVF-MYGKCGSLDDAEKVFDEMPDRTAFAWNTMIGAYVSNGEPASALALYWNMRVEGVPLGLSSFPALLKACAKLRDIRSGSELHSLLVKLGYHSTGFIVNALVSMYAKNDDLSAARRLFDGFQEKGDAVLWNSILSSYSTSGKSLETLELFREMHMTGPAPNSYTIVSALTACDGFSYAKLGKEIHASVLK--SSTHSSELYVCNALIAMYTRCGKMPQAERILRQMN-NADVVTWNSLI 358          

Query:  226 SLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLY-YDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTM-VGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSG-FDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +L  AK +H  L+   ++      +  K+ +LY     V LA   FD I    V  WNL+I  Y   G     I  +   +L SG+ P   T+P VLKAC   + +  G +IH  A   G   DVYV  +LI LY++   +  A+ +F  M  +D+ +WNAMI+G+   G   + + +   ++    + ++ T+V++L    +A   ++G  +H +S++  L  E+ +   L+D+Y++   +   +++FD + V++ + W+++I AY + +    A++LF EM L + I P  +TL S+    ++L D+   R V  + ++ G+ L  + +GN ++ MYAK G++D A   F+ + + D +S++ IISG  QNG+A EA+ +++ M+  G    +  T V VLPACS   AL+ G   H   + +G   D  +   L DMY KCG++     +F ++   + + WN +I  +G HG G  A+  F  ML  G+KPD +TF+ LLSACSHSGLV EG+  F  M  D+ ITP ++HY CMVD+ GRAG L  A  FI+ M  + D  +W ALL+ACRVH N++LG+  S+ +     E  G  VLLSN+Y++ G+W+    +R    G+GL+K+PG S +E++  +  F  G+Q+HP   +++ +L  L   +K +GY  ++ FVLQDVE++EKE IL+ HSE+LAIA+A+++      I + KNLRVCGDCH+  K I+ IT+REIIVRD  RFHHFK+G+C+C D+W
Sbjct:   66 NLQSAKCLHARLV--VSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKAC---RTVIDGNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTLSNGLR----AMDSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSR-IQPDCLTLISLASILSQLGDIRACRSVQGFTLRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLLKNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEGVKPDHITFVTLLSACSHSGLVDEGQWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVDLGKIASEHLFEVEPEHVGYHVLLSNMYASAGKWEGVDEIRSIAHGKGLRKTPGWSSMEVDNKVEVFYTGNQTHPMYEEMYRELTALQAKLKMIGYVPDHRFVLQDVEDDEKEHILMSHSERLAIAFALIATPAKTTIRIFKNLRVCGDCHSVTKFISKITEREIIVRDSNRFHHFKNGVCSCGDYW 823          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKA-LGLASDVYVCTALIDLYAKCGGLAEAQTVFRGM-LYKDVVAWNAMIAGFSLHGLYD 741
            C ++ +L Q  K+H  LLKN   L    F++  +A +Y  C +++ A  +F +IP+ + + WN LI  + ++G  E+A+ L+ ++L  GVKP   T+  +L ACS    ++ G+   +  +   G+   +     ++D+Y + G L  A    + M L  D   W A+++   +HG  D
Sbjct:  461 CSQAGALRQGMKLHGRLLKNGLYL--DVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEGVKPDHITFVTLLSACSHSGLVDEGQWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVD 637          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQ---PSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALG-LASDVYVCTALIDLYAKCGGLAE-AQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQC---IAYARRIFDAIDVKNEVCWSAMIGAYVI-CDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEE----EKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +CIR++     K +H  L++    ++  S L   +  LY        A  VF+ + +     V+ W+ ++  Y  NG    AI ++ + L+ G+ P  Y Y  V++ACS    +  GR         G   SDV V  +LID++ K     E A  VF  M   +VV W  MI      G   + I+  + M  +G   +  T+ +V    A+   LS GK +H +++R  L  +V     L+DMY+KC     +   R++FD ++  + + W+A+I  Y+  C+   EA+ LF EM+ +  + P   T  S  +AC  L+D   G++V   A K G   N+ V N+++SM+ K   ++DA R F+ ++ K+ VSY+  + G  +N   ++A  +   +          T   +L   +++ +++ G   H+  +  G   +  +CN LI MYSKCG I+   +VF+ M  R++ISW +MI G+  HG  +  +  F+ M+  G+KP++VT++ +LSACSH GLV+EG   FN+M ED  I P+MEHY CMVDLL RAG L +A  FI  MPF+ADV VW   L ACRVH+N ELG+  ++KI           + LSNIY+  G+W+++  +R K K + L K  GCSW+E+   IH F  GD +HP + QI+++L+ L+ ++KR GY  +   VL  +EEE    EKER+L  HSEK+A+A+ ++S    +P+ V KNLRVCGDCH A+K I+ ++ REI++RDL RFHHFKDG C+C D+W
Sbjct:   71 SCIRARDFRLGKLVHARLIEFD--IEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDDVECS--LVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVVKLGLSCNQPVCNALISMYSKCGSIDTASRVFNFMENRNVISWTSMITGFAKHGFAIRVLETFNQMIEEGVKPNEVTYVAILSACSHVGLVSEGWRHFNSMYEDHKIKPKMEHYACMVDLLCRAGLLTDAFEFINTMPFQADVLVWRTFLGACRVHSNTELGKLAARKILELDPNEPAAYIQLSNIYACAGKWEESTEMRRKMKERNLVKEGGCSWIEVGDKIHKFYVGDTAHPNAHQIYDELDRLITEIKRCGYVPDTDLVLHKLEEENDEAEKERLLYQHSEKIAVAFGLISTSKSRPVRVFKNLRVCGDCHNAMKYISTVSGREIVLRDLNRFHHFKDGKCSCNDYW 850          

Query:  463 LLQSGVKPT-KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML---YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRS-LSGEVVLGTGLLDMYSKCQ-CIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKC---GIIDDAVRFFDKMNSKDTVSYSAIISGCVQN-GYAKEALLIFHHMQLSG-FDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK 1767
            + + G++P    T+  +LK+C   +    G+ +H       +  D  +  +LI LY+K G  A+A+ VF  M     +DVV+W+AM+A +  +G   D I++ V+  + G  PN     AV+   + ++ +  G+   GF ++      +V +G  L+DM+ K +     A ++FD +   N V W+ MI   +     REA+  F +MVL         TL S+  AC +L +LS G+++H +AI+SG  L   V  +++ MYAKC   G +DD  + FD+M     +S++A+I+G ++N   A EA+ +F  M   G  +P+  T      AC +L+  + G      +   G  +++S+ N +I M+ K  ++   ++ F+ +  ++++S+N  + G   +     A      +    +     TF  LLS  ++ G + +G+
Sbjct:   52 MARDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVL-SGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSG--LVDDVECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGE 494          

Query: 1039 MREAMALFDEMVLRKEINPTP-VTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKM---NSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHG-FGTDTSICNVLIDMYSKC-GKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKH---WF--NAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEG--TGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRL--GYCAENSF-----VLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPI 2373
            +R A++  D M  R  I P   VT  S+L++C +  D   G+ VH   I+   + ++++ N+++S+Y+K G    A   F+ M     +D VS+SA+++    NG   +A+ +F      G  P+      V+ ACS+   +  G     + +  G F +D  +   LIDM+ K         +VFD+M   ++++W  MI      G    AI  F  M+ +G + D  T   + SAC+    ++ GK    W   + + +D   +    +  C  D     G + +      +M  +  V  W+AL+       N  L  E          +G    N    S+ + A G   D   V  +  GQ  K+    +    N +I  FV  D+            E+ LV       G C   +F     +L ++ E E        +  L+    + S+R G+ I
Sbjct:   42 LRGAVSALDLMA-RDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDDVECSLVDMYAKCSAD-----GSVDDCRKVFDRME-DHSVMSWTALITG--YMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPR-VGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQI 496          

Query:  217 RSKSLPQAKKIHQHLLK-NTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIP--QPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQM-QKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEM----------------------------------VLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLN-------TMVGNTILSMYAKCGIIDDAVRFFDKMNSK--DTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFD--PDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGT-DTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVE-INGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            + K++ Q K IHQ LL      L  TS L+      YI+   +  A  +    P     V  WN LIR+Y  NG   + ++L+  +      P  YT+PFV KAC  + ++  G   H  +   G  S+V+V  AL+ +Y++C  L++A+ VF  M   DVV+WN++I  ++  G     ++M  +M  + G  P+  T+V VLP  A     S GK +H F++   +   + +G  L+DMY+KC  +  A  +F  + VK+ V W+AM+  Y       +A+ LF++M                                  +L   I P  VTL S+L  C  +  L  G+ +HCYAIK   DL         MV N ++ MYAKC  +D A   FD ++ K  D V+++ +I G  Q+G A +AL +   M        P+  T+   L AC+ LAAL+ G   HAY++ +        + N LIDMY+KCG I+  R VFD M+ ++ ++W +++ GYG+HG G  A+  F  M   G K D VT + +L ACSHSG++ +G  +FN M   F ++P  EHY C+VDLLGRAG L  A   I++MP E    VW A L+ CR+H  +ELGE  ++KI        G+  LLSN+Y+  GRW D   +R   + +G+KK PGCSWVE I G    FV GD++HP + +I++ L + +  +K +GY  E  F L DV++EEK+ +L  HSEKLA+AY IL+   G  I +TKNLRVCGDCH A   ++ I   +II+RD +RFHHFK+G C+C  +W
Sbjct:   37 KCKTISQVKLIHQKLLSFGILTLNLTSHLIST----YISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLFGLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAYALRNQQNAVPLFVSNCLIDMYAKCGSISDARLVFDNMMAKNEVTWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVLYACSHSGMIDQGMEYFNRMKTVFGVSPGPEHYACLVDLLGRAGRLNAALRLIEEMPMEPPPVVWVAFLSCCRIHGKVELGEYAAEKITELASNHDGSYTLLSNLYANAGRWKDVTRIRSLMRHKGVKKRPGCSWVEGIKGTTTFFV-GDKTHPHAKEIYQVLLDHMQRIKDIGYVPETGFALHDVDDEEKDDLLFEHSEKLALAYGILTTPQGAAIRITKNLRVCGDCHTAFTYMSRIIDHDIILRDSSRFHHFKNGSCSCKGYW 850          

Query:  448 HLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKD--VVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIID-------------------------------DAVRFFDKMNSK----DTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVH-------GFGTDTSICNVLIDMYSKCGKINRGRQVFDRM--VTRDIISWNAMIVGYGIHGLGMAAISQFHHMLA--AGIKPDDVTFIGLLSACSHSGLVTEGK--HWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIE--LGEEVSKKIQGKGLEGTGNLVLL 2031
            H Y  +        + T PF+ K     + +   + IHQ   + G+ + + + + LI  Y   G L+ A ++ R     D  V  WN++I  +  +G  +  + +   M     +P+  T   V     + +++  G++ H  SL       V +G  L+ MYS+C+ ++ AR++FD + V + V W+++I +Y      + A+ +F  M       P  +TL ++L  C  L   S G+++HC+A+ S    N  VGN ++ MYAKCG++D                               DAVR F+KM  +    D V++SA ISG  Q G   EAL +   M  SG  P+  T++ VL  C+ + AL HG   H Y+I +       G G +  + N LIDMY+KC K++  R +FD +    RD+++W  MI GY  HG    A+     M       +P+  T    L AC+    +  GK  H + A+    N  P      C++D+  + G +++A +    M  + +V  W++L+    +H   E  LG     +  G  L+G   LV+L
Sbjct:   15 HQYIKVSLFSTSAPEITPPFIHKC----KTISQVKLIHQKLLSFGILT-LNLTSHLISTYISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLFGLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAY-ALRNQQNAVPLFVSN-CLIDMYAKCGSISDARLVFDNMMAKNEV-TWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVL 586          

Query:  295 FLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDV-EEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            F+   +  +Y     +  A +VFDE+P   ++ WN LI  Y+ +G +E A+ +Y++L  S + P  +T   VL A   L  ++ G+ +H  A   G+ S V V   L+ +Y K     +A+ VF  M  +D V++N MI G+    + +++++M ++       P+  T+ +VL        LS  K ++ + L+     E  +   L+D+Y+KC  +  AR +F++++ K+ V W+++I  Y+    + EAM LF  M++ +E     +T   ++   T+L DL  G+ +H   IKSG  ++  V N ++ MYAKCG + D+++ F  M + DTV+++ +IS CV+ G     L +   M+ S   PD+AT +  LP C+ LAA + G   H   +  G+ ++  I N LI+MYSKCG +    +VF+RM  RD+++W  MI  YG++G G  A+  F  M  +GI PD V FI ++ ACSHSGLV EG   F  M   + I P +EHY C+VDLL R+  +++A  FIQ MP + D  +W+++L ACR   ++E  E VS++I     +  G  +L SN Y+A+ +WD  + +R   K + + K+PG SW+E+   +H F  GD S PQS  I++ LE L   M + GY  +   V Q++ EEEEK R++  HSE+LAIA+ +L+  PG P+ V KNLRVCGDCH   K+I+ I  REI+VRD  RFH FKDG C+C D W
Sbjct:  142 FVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEE-QADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIVPDSVVFIAIIYACSHSGLVDEGLACFEKMKTHYKIDPMIEHYACVVDLLSRSQKISKAEEFIQAMPIKPDASIWASVLRACRTSGDMETAERVSRRIIELNPDDPGYSILASNAYAALRKWDKVSLIRKSLKDKHITKNPGYSWIEVGKNVHVFSSGDDSAPQSEAIYKSLEILYSLMAKEGYIPDPREVSQNLEEEEEKRRLICGHSERLAIAFGLLNTEPGTPLQVMKNLRVCGDCHEVTKLISKIVGREILVRDANRFHLFKDGTCSCKDRW 882          

Query:  220 SKSLPQAKKIHQHLLKNTTRLKD--TSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMI---VGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYS 2046
            S +L + ++IH  ++       D  +  L++K +H     + + +  RV    P  +V LWN +IRA++ NG F  A+  Y  L +S V P KYT+P V+KAC+GL   E G  +++    +G  SD++V  AL+D+Y++ G L  A+ VF  M  +D+V+WN++I+G+S HG Y++ +++  +++ +   P++ T+ +VLP       + QG+ +HGF+L+  ++  VV+  GL+ MY K +    ARR+FD +DV++ V ++ MI  Y+  + + E++ +F E +   +  P  +T+ S+LRAC  L DLS  + ++ Y +K+GF L + V N ++ +YAKCG +  A   F+ M  KDTVS+++IISG +Q+G   EA+ +F  M +     D  T + ++   + LA L+ G   H+  I  G   D S+ N LIDMY+KCG++    ++F  M T D ++WN +I   V +G    G+   +Q   M  + + PD  TF+  L  C+       GK   +     F     ++    ++++  + G L  +    ++M    DV  W+ ++ A  ++   E   E    ++  G+    ++V ++ IY+
Sbjct:   17 SSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVS---PAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENL--DQFKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQ---MRKSEVVPDMATFLVTLPMCASLAAKRLGKE-IHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMS-RRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIV-PDSVVFIAIIYA 619          

Query:  487 TKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML-YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWF-NAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQ 1992
            T+ + PF+ +A S    L   R IH    +LGL S  +    LID Y+     A + +VFR +   K+V  WN++I  FS +GL+ + ++   +++++  SP+  T  +V+   A       G  ++   L      ++ +G  L+DMYS+   +  AR++FD + V++ V W+++I  Y       EA+ ++ E+     I P   T+ S+L A   L  + +G+ +H +A+KSG +   +V N +++MY K     DA R FD+M+ +D+VSY+ +I G ++    +E++ +F    L  F PDL T+  VL AC HL  L      + Y +  GF  ++++ N+LID+Y+KCG +   R VF+ M  +D +SWN++I GY   G  M A+  F  M+    + D +T++ L+S  +    +  GK    N +     I   + +   ++D+  + G + ++      M    D   W+ +++AC    +   G +V+ +++
Sbjct:    3 TRVSSPFISRALSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHEL-KNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLE-NLDQFKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSN--ALIDMYAKCGEVGDSLKIFSSMG-TGDTVTWNTVISACVRFGDFATGLQVTTQMR 501          

Query:  385 VILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQA-NALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +I  N  +  Y  +G +   +  + D+++S V+  + T+  +L     + +L  G+++H  A  LGL   + V  +LI++Y K      A+TVF  M  +D+++WN++IAG + +GL  + + + +Q+ + G  P+  T+ +VL   +     LS  K +H  +++ +   +  + T L+D YS+ +C+  A  +F+  +  + V W+AM+  Y       + + LF  M  + E      TL ++ + C  L  +++G++VH YAIKSG+DL+  V + IL MY KCG +  A   FD +   D V+++ +ISGC++NG  + A  +F  M+L G  PD  T+  +  A S L AL+ G   HA ++      D  +   L+DMY+KCG I+    +F R+   +I +WNAM+VG   HG G   +  F  M + GIKPD VTFIG+LSACSHSGLV+E      +M  D+ I P +EHY C+ D LGRAG + +A   I+ M  EA   ++  LLAACRV  + E G+ V+ K+       +   VLLSN+Y+A  +WD+    R   KG  +KK PG SW+E+   IH FV  D+S+ Q+  I+ K+++++ D+K+ GY  E  F L DVEEEEKER L YHSEKLA+A+ +LS  P  PI V KNLRVCGDCH A+K I  +  REI++RD  RFH FKDGIC+C D+W
Sbjct:  280 IIFRNKGLSEYLHSGQYSALLKCFADMVESDVECDQVTFILMLATAVKVDSLALGQQVHCMALKLGLDLMLTVSNSLINMYCKLRKFGFARTVFDNMSERDLISWNSVIAGIAQNGLEVEAVCLFMQLLRCGLKPDQYTMTSVLKAASSLPEGLSLSKQVHVHAIKINNVSDSFVSTALIDAYSRNRCMKEAEILFERHNF-DLVAWNAMMAGYTQSHDGHKTLKLFALMHKQGE-RSDDFTLATVFKTCGFLFAINQGKQVHAYAIKSGYDLDLWVSSGILDMYVKCGDMSAAQFAFDSIPVPDDVAWTTMISGCIENGEEERAFHVFSQMRLMGVLPDEFTIATLAKASSCLTALEQGRQIHANALKLNCTNDPFVGTSLVDMYAKCGSIDDAYCLFKRIEMMNITAWNAMLVGLAQHGEGKETLQLFKQMKSLGIKPDKVTFIGVLSACSHSGLVSEAYKHMRSMHGDYGIKPEIEHYSCLADALGRAGLVKQAENLIESMSMEASASMYRTLLAACRVQGDTETGKRVATKLLELEPLDSSAYVLLSNMYAAASKWDEMKLARTMMKGHKVKKDPGFSWIEVKNKIHIFVVDDRSNRQTELIYRKVKDMIRDIKQEGYVPETDFTLVDVEEEEKERALYYHSEKLAVAFGLLSTPPSTPIRVIKNLRVCGDCHNAMKYIAKVYNREIVLRDANRFHRFKDGICSCGDYW 990          

Query:  214 IRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGP-----FERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHL-AALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK--HWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEE 1974
            I S  L   K  H  +L  T       FL+  +  +Y  C  +  A RVFD++P   ++ WN ++ AYA +        ++A  L+  L Q  V  ++ T   +LK C     + A    H +A  +GL  D +V  AL+++Y K G + E + +F  M Y+DVV WN M+  +   G  ++ I +      +G +PN  T+  +       +   Q K+    +   S+S  +    GL +     Q  A  +            C++ M+ + V CD                      VT   +L    K+  L+ G++VHC A+K G DL   V N++++MY K      A   FD M+ +D +S++++I+G  QNG   EA+ +F  +   G  PD  TM  VL A S L   L      H ++I     +D+ +   LID YS+   +     +F+R    D+++WNAM+ GY     G   +  F  M   G + DD T   +   C     + +GK  H + A+   +++   +   I  +D+  + G ++ A      +P   DV  W+ +++ C     IE GEE
Sbjct:   50 ITSSDLMLGKCTHARIL--TFEENPERFLINNLISMYSKCGSLTYARRVFDKMPDRDLVSWNSILAAYAQSSECVVENIQQAFLLFRILRQDVVYTSRMTLSPMLKLCLHSGYVWASESFHGYACKIGLDGDEFVAGALVNIYLKFGKVKEGKVLFEEMPYRDVVLWNLMLKAYLEMGFKEEAIDLSSAFHSSGLNPNEITLRLLARISGDDSDAGQVKSFANGNDASSVSEIIFRNKGLSEYLHSGQYSALLK------------CFADMVESDVECDQ---------------------VTFILMLATAVKVDSLALGQQVHCMALKLGLDLMLTVSNSLINMYCKLRKFGFARTVFDNMSERDLISWNSVIAGIAQNGLEVEAVCLFMQLLRCGLKPDQYTMTSVLKAASSLPEGLSLSKQVHVHAIKINNVSDSFVSTALIDAYSRNRCMKEAEILFERH-NFDLVAWNAMMAGYTQSHDGHKTLKLFALMHKQGERSDDFTLATVFKTCGFLFAINQGKQVHAY-AIKSGYDLDLWVSSGI--LDMYVKCGDMSAAQFAFDSIPVPDDV-AWTTMISGC-----IENGEE 599          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQG----KAMHG 867
            TC    ++ Q K++H + +K+   L    ++   +  +Y+ C  +  A   FD IP P  + W  +I     NG  ERA H++  +   GV P ++T   + KA S L ALE GR+IH +A  L   +D +V T+L+D+YAKCG + +A  +F+ +   ++ AWNAM+ G + HG   +T+Q+  QM+  G  P+  T + VL   + +  +S+     ++MHG
Sbjct:  526 TCGFLFAINQGKQVHAYAIKSGYDLD--LWVSSGILDMYVKCGDMSAAQFAFDSIPVPDDVAWTTMISGCIENGEEERAFHVFSQMRLMGVLPDEFTIATLAKASSCLTALEQGRQIHANALKLNCTNDPFVGTSLVDMYAKCGSIDDAYCLFKRIEMMNITAWNAMLVGLAQHGEGKETLQLFKQMKSLGIKPDKVTFIGVLSACSHSGLVSEAYKHMRSMHG 747          

Query:  775 AGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYV-----ICDSMREAMALFDEMVLRKEINPTP-VTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATM 1413
            + +S ++S     L     ++ L  GK  H   L    + E  L   L+ MYSKC  + YARR+FD +  ++ V W++++ AY      + +++++A  LF   +LR+++  T  +TL  +L+ C     +      H YA K G D +  V   ++++Y K G + +    F++M  +D V ++ ++   ++ G+ +EA+ +      SG +P+  T+
Sbjct:   33 SSSSSSSSQWFGFLRNAITSSDLMLGKCTHARILTFEENPERFLINNLISMYSKCGSLTYARRVFDKMPDRDLVSWNSILAAYAQSSECVVENIQQAFLLF--RILRQDVVYTSRMTLSPMLKLCLHSGYVWASESFHGYACKIGLDGDEFVAGALVNIYLKFGKVKEGKVLFEEMPYRDVVLWNLMLKAYLEMGFKEEAIDLSSAFHSSGLNPNEITL 249          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSV--ILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKA-GTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINP-TPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSE-DFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEI 2139
            TCIRS++L   + IHQHLLK +  L  ++ L+  +  LY +CN+V+LA  VFDEIP P +  I W+L+IRAYA N   E+A+ LYY +L SGV+PTKYTYPFVLKAC+GL+A++ G+ IH H      A+D+YVCTAL+D YAKCG L  A  VF  M  +D+VAWNAMI+GFSLH    D I + + M++  G SPN STIV + P + +A AL +GKA+HG+  R   S ++V+ TG+LD+Y+K +CI YARR+FD    KNEV WSAMIG YV  + ++EA  +F +M++   +   TPV +G IL  C +  DLS GR VHCYA+K+GF L+  V NTI+S YAK G + DA R F ++  KD +SY+++I+GCV N   +E+  +FH M+ SG  PD+ T++GVL ACSHLAAL HG+  H Y +VHG+  +TSICN L+DMY+KCGK++  ++VFD M  RDI+SWN M+ G+GIHGLG  A+S F+ M   G+ PD+VT + +LSACSHSGLV EGK  FN+MS  DFN+ PR++HY CM DLL RAG+L EA+ F+ KMPFE D+RV   LL+AC  + N ELG EVSKK+Q  G E T +LVLLSN YSA  RW+DAA +R+ QK +GL K+PG SWV++
Sbjct:    8 TCIRSRNLVLGQVIHQHLLKRSLTLSSSTVLVN-LTRLYASCNEVELARHVFDEIPHPRINPIAWDLMIRAYASNDFAEKALDLYYKMLNSGVRPTKYTYPFVLKACAGLRAIDDGKLIHSHVNCSDFATDMYVCTALVDFYAKCGELEMAIKVFDEMPKRDMVAWNAMISGFSLHCCLTDVIGLFLDMRRIDGLSPNLSTIVGMFPALGRAGALREGKAVHGYCTRMGFSNDLVVKTGILDVYAKSKCIIYARRVFDLDFKKNEVTWSAMIGGYVENEMIKEAGEVFFQMLVNDNVAMVTPVAIGLILMGCARFGDLSGGRCVHCYAVKAGFILDLTVQNTIISFYAKYGSLCDAFRQFSEIGLKDVISYNSLITGCVVNCRPEESFRLFHEMRTSGIRPDITTLLGVLTACSHLAALGHGSSCHGYCVVHGYAVNTSICNALMDMYTKCGKLDVAKRVFDTMHKRDIVSWNTMLFGFGIHGLGKEALSLFNSMQETGVNPDEVTLLAILSACSHSGLVDEGKQLFNSMSRGDFNVIPRIDHYNCMTDLLARAGYLDEAYDFVNKMPFEPDIRVLGTLLSACWTYKNAELGNEVSKKMQSLG-ETTESLVLLSNTYSAAERWEDAARIRMIQKKRGLLKTPGYSWVDV 654          

Query:  217 RSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            R  SL + ++I   + KN   L    F   K+  L+     VD A+RVF+ I     +L++ +++ +A     ++A+  +  +    V+P  Y + ++LK C     L  G+EIH      G + D++  T L ++YAKC  + EA+ VF  M  +D+V+WN ++AG+S +G+    ++M+  M +    P+  TIV+VLP V+    +S GK +HG+++R      V + T L+DMY+KC  +  AR++FD +  +N V W++MI AYV  ++ +EAM +F +M L + + PT V++   L AC  L DL RGR +H  +++ G D N  V N+++SMY KC  +D A   F K+ S+  VS++A+I G  QNG   +AL  F  M+     PD  T V V+ A + L+   H    H   +      +  +   L+DMY+KCG I   R +FD M  R + +WNAMI GYG HG G AA+  F  M    IKP+ VTF+ ++SACSHSGLV  G   F  M E+++I   M+HY  MVDLLGRAG L EA  FI +MP +  V V+ A+L AC++H N+   E+ ++++     +  G  VLL+NIY A   W+    VR+    QGL+K+PGCS VEI   +H F  G  +HP S +I+  LE+L+  +K  GY  + + VL  VE + KE++L  HSEKLAI++ +L+   G  I V KNLRVC DCH A K I+L+T REI+VRD+ RFHHFK+G C+C D+W
Sbjct:   46 RCSSLKELRQILPLVFKNG--LYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKM-LDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQMPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSKKIYAFLEKLICHIKEAGYVPDTNLVL-GVENDVKEQLLSTHSEKLAISFGLLNTTAGTTIHVRKNLRVCADCHNATKYISLVTGREIVVRDMQRFHHFKNGACSCGDYW 809          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHM-QLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            C  SKSL   K++   +  N   +   S L  K++ +Y  C  +  ASRVFDE+     + WN+L+   A +G F  +I L+  ++ SGV+   YT+  V K+ S L+++  G ++H      G      V  +L+  Y K   +  A+ VF  M  +DV++WN++I G+  +GL +  + + VQM  +G   + +TIV+V    A +  +S G+A+H   ++   S E      LLDMYSKC  +  A+ +F  +  ++ V +++MI  Y       EA+ LF+EM   + I+P   T+ ++L  C +   L  G+RVH +  ++    +  V N ++ MYAKCG + +A   F +M  KD +S++ II G  +N YA EAL +F+ + +   F PD  T+  VLPAC+ L+A   G   H Y + +G+ +D  + N L+DMY+KCG +     +FD + ++D++SW  MI GYG+HG G  AI+ F+ M  AGI+ D+++F+ LL ACSHSGLV EG  +FN M  +  I P +EHY C+VD+L R G L +A+ FI+ MP   D  +W ALL  CR+H++++L E+V++K+     E TG  VL++NIY+   +W+    +R +   +GL+K+PGCSW+EI G ++ FV GD S+P++  I   L ++   M   GY     + L D EE EKE  L  HSEKLA+A  I+S   GK I VTKNLRVCGDCH   K ++ +T+REI++RD  RFH FKDG C+C  FW
Sbjct:  104 CADSKSLKDGKEVDNFIRGNGFVID--SNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEME-EEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDRHVANSLVDMYAKCGALLLAHMLFDDIASKDLVSWTVMIAGYGMHGFGKEAIALFNQMRQAGIEADEISFVSLLYACSHSGLVDEGWRFFNIMRHECKIEPTVEHYACIVDMLARTGDLIKAYRFIENMPIPPDATIWGALLCGCRIHHDVKLAEKVAEKVFELEPENTGYYVLMANIYAEAEKWEQVKRLRKRIGQRGLRKNPGCSWIEIKGRVNIFVAGDSSNPETENIEAFLRKVRARMIEEGYSPLTKYALIDAEEMEKEEALCGHSEKLAMALGIISSGHGKIIRVTKNLRVCGDCHEMAKFMSKLTRREIVLRDSNRFHQFKDGHCSCRGFW 871          

Query:  397 NLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHML-AAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYI-CMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            N  +R +  +G  E A+ L     +  + P   T   VL+ C+  ++L+ G+E+    +  G   D  + + L  +Y  CG L EA  VF  +  +  + WN ++   +  G +  +I +  +M  +G   ++ T   V  + +   ++  G+ +HGF L+        +G  L+  Y K Q +  AR++FD +  ++ + W+++I  YV      + +++F +M++   I     T+ S+   C     +S GR VH   +K+ F       NT+L MY+KCG +D A   F +M+ +  VSY+++I+G  + G A EA+ +F  M+  G  PD+ T+  VL  C+    L  G   H +   +  G D  + N L+DMY+KCG +     VF  M  +DIISWN +I GY  +     A+S F+ +L      PD+ T   +L AC+      +G+     +  +   + R  H    +VD+  + G L  AH+    +    D+  W+ ++A   +H
Sbjct:   65 NTQLRRFCESGNLENAVKLLCVSGKWDIDPR--TLCSVLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLV-SGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDR--HVANSLVDMYAKCGALLLAHMLFDDIA-SKDLVSWTVMIAGYGMH 578          

Query:  241 KKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGL---QALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR-SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQ-----------LSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEAD-VRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            K+IH H+ K    + D+  +   + +LY  C       +VFD I + + + WN LI +      +E A+  +  +L   V+P+ +T   V+ ACS L   + L  G+++H +    G  +  ++   L+ +Y K G LA ++ +      +D+V WN +++    +    + ++ L +M   G  P+  TI +VLP  +    L  GK +H ++L+  SL     +G+ L+DMY  C+ +   RR+FD +  +    W+AMI  Y   +  +EA+ LF  M     +     T+  ++ AC +    SR   +H + +K G D +  V NT++ MY++ G ID A+R F KM  +D V+++ +I+G V + + ++ALL+ H MQ                P+  T++ +LP+C+ L+AL  G   HAY+I +   TD ++ + L+DMY+KCG +   R+VFD++  +++I+WN +I+ YG+HG G  AI     M+  G+KP++VTFI + +ACSHSG+V EG   F  M  D+ + P  +HY C+VDLLGRAG + EA+  +  MP + +    WS+LL A R+HNN+E+GE  ++ +         + VLL+NIYS+ G WD A  VR   K QG++K PGCSW+E    +H FV GD SHPQS ++   LE L   M++ GY  + S VL +VEE+EKE +L  HSEKLAIA+ IL+  PG  I V KNLRVC DCH A K I+ I  REII+RD+ RFH FK+G C+C D+W
Sbjct:  117 KQIHAHVYKFGYGV-DSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNS-FIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYLETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:  220 SKSLPQAKKIHQHLLKNT--TRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASD-VYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVL---PTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSG-FDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLS-GFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHM-----------LAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSA 2049
            S+ LP ++  H +LL+ T  +  +D +  +     ++I+ ++              S   W  L+R+   +     A+  Y D++  G+KP  Y +P +LKA + LQ +E G++IH H    G   D V V   L++LY KCG       VF  +  ++ V+WN++I+       ++  ++    M      P++ T+V+V+     +     L  GK +H + LR+      ++ T L+ MY K   +A ++ +  +   ++ V W+ ++ +    + + EA+    EMVL + + P   T+ S+L AC+ L  L  G+ +H YA+K+G  D N+ VG+ ++ MY  C  +    R FD M  +    ++A+I+G  QN + KEALL+F  M+ S G   +  TM GV+PAC    A       H + +  G   D  + N L+DMYS+ GKI+   ++F +M  RD+++WN MI GY        A+   H M               +KP+ +T + +L +C+    + +GK   +A +   N+   +     +VD+  + G L  +     ++P + +V  W+ ++ A  +H N +   ++ + +  +G++   N V   ++++A
Sbjct:   19 SQLLPFSRHKHPYLLRATPTSATEDVASAVSGAPSIFISQSR--------------SPEWWIDLLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNSFIINT-LVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVL-EGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKE-IHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIP-QKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVK--PNEVTFISVFAA 627          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAK---ALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML--YKDVVAWNAMIAGFSLHG---LYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANAL 843
            +C    +L + K+IH + +KN   L     +   +  +Y  C  + ++ +VFD+IPQ +VI WN++I AY  +G  + AI L   ++  GVKP + T+  V  ACS    ++ G  I    K    +  +SD Y C  ++DL  + G + EA  +   M   +    AW++++    +H    + +   Q L+Q++     PN ++   +L  +  +  L
Sbjct:  526 SCAALSALAKGKEIHAYAIKN--NLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYAC--VVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLE-----PNVASHYVLLANIYSSAGL 736          

Query:  226 SLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLY-YDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTM-VGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSG-FDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +L  AK +H  L+   ++      +  K+ +LY     V LA   FD I    V  WNL+I  Y   G     I  +   +L SG+ P   T+P VLKAC   + +  G +IH  A   G   DVYV  +LI LY++   +  A+ +F  M  +D+ +WNAMI+G+   G   + + +   ++    + ++ T+V++L    +A   ++G  +H +S++  L  E+ +   L+D+Y++   +   +++FD + V++ + W+++I AY + +    A++LF EM L + I P  +TL S+    ++L D+   R V  + ++ G+ L  + +GN ++ MYAK G++D A   F+ + + D +S++ IISG  QNG+A EA+ +++ M+  G    +  T V VLPACS   AL+ G   H   + +G   D  +   L DMY KCG++     +F ++   + + WN +I  +G HG G  A+  F  ML  G+KPD +TF+ LLSACSHSGLV EG+  F  M  D+ ITP ++HY CMVD+ GRAG L  A  FI+ M  + D  +W ALL+ACRVH N++LG+  S+ +     E  G  VLLSN+Y++ G+W+    +R    G+GL+K+PG S +E++  +  F  G+Q+HP   +++ +L  L   +K +GY  ++ FVLQDVE++EKE IL+ HSE+LAIA+A+++      I + KNLRVCGDCH+  K I+ IT+REIIVRD  RFHHFK+G+C+C D+W
Sbjct:   66 NLQSAKCLHARLV--VSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKAC---RTVIDGNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTLSNGLR----AMDSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSR-IQPDCLTLISLASILSQLGDIRACRSVQGFTLRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLLKNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEGVKPDHITFVTLLSACSHSGLVDEGQWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVDLGKIASEHLFEVEPEHVGYHVLLSNMYASAGKWEGVDEIRSIAHGKGLRKTPGWSSMEVDNKVEVFYTGNQTHPMYEEMYRELTALQAKLKMIGYVPDHRFVLQDVEDDEKEHILMSHSERLAIAFALIATPAKTTIRIFKNLRVCGDCHSVTKFISKITEREIIVRDSNRFHHFKNGVCSCGDYW 823          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKA-LGLASDVYVCTALIDLYAKCGGLAEAQTVFRGM-LYKDVVAWNAMIAGFSLHGLYD 741
            C ++ +L Q  K+H  LLKN   L    F++  +A +Y  C +++ A  +F +IP+ + + WN LI  + ++G  E+A+ L+ ++L  GVKP   T+  +L ACS    ++ G+   +  +   G+   +     ++D+Y + G L  A    + M L  D   W A+++   +HG  D
Sbjct:  461 CSQAGALRQGMKLHGRLLKNGLYL--DVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEGVKPDHITFVTLLSACSHSGLVDEGQWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVD 637          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQ---PSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALG-LASDVYVCTALIDLYAKCGGLAE-AQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQC---IAYARRIFDAIDVKNEVCWSAMIGAYVI-CDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEE----EKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +CIR++     K +H  L++    ++  S L   +  LY        A  VF+ + +     V+ W+ ++  Y  NG    AI ++ + L+ G+ P  Y Y  V++ACS    +  GR         G   SDV V  +LID++ K     E A  VF  M   +VV W  MI      G   + I+  + M  +G   +  T+ +V    A+   LS GK +H +++R  L  +V     L+DMY+KC     +   R++FD ++  + + W+A+I  Y+  C+   EA+ LF EM+ +  + P   T  S  +AC  L+D   G++V   A K G   N+ V N+++SM+ K   ++DA R F+ ++ K+ VSY+  + G  +N   ++A  +   +          T   +L   +++ +++ G   H+  +  G   +  +CN LI MYSKCG I+   +VF+ M  R++ISW +MI G+  HG  +  +  F+ M+  G+KP++VT++ +LSACSH GLV+EG   FN+M ED  I P+MEHY CMVDLL RAG L +A  FI  MPF+ADV VW   L ACRVH+N ELG+  ++KI           + LSNIY+  G+W+++  +R K K + L K  GCSW+E+   IH F  GD +HP + QI+++L+ L+ ++KR GY  +   VL  +EEE    EKER+L  HSEK+A+A+ ++S    +P+ V KNLRVCGDCH A+K I+ ++ REI++RDL RFHHFKDG C+C D+W
Sbjct:   71 SCIRARDFRLGKLVHARLIEFD--IEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDDVECS--LVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVVKLGLSCNQPVCNALISMYSKCGSIDTASRVFNFMENRNVISWTSMITGFAKHGFAIRVLETFNQMIEEGVKPNEVTYVAILSACSHVGLVSEGWRHFNSMYEDHKIKPKMEHYACMVDLLCRAGLLTDAFEFINTMPFQADVLVWRTFLGACRVHSNTELGKLAARKILELDPNEPAAYIQLSNIYACAGKWEESTEMRRKMKERNLVKEGGCSWIEVGDKIHKFYVGDTAHPNAHQIYDELDRLITEIKRCGYVPDTDLVLHKLEEENDEAEKERLLYQHSEKIAVAFGLISTSKSRPVRVFKNLRVCGDCHNAMKYISTVSGREIVLRDLNRFHHFKDGKCSCNDYW 850          

Query:  463 LLQSGVKPT-KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML---YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRS-LSGEVVLGTGLLDMYSKCQ-CIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKC---GIIDDAVRFFDKMNSKDTVSYSAIISGCVQN-GYAKEALLIFHHMQLSG-FDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK 1767
            + + G++P    T+  +LK+C   +    G+ +H       +  D  +  +LI LY+K G  A+A+ VF  M     +DVV+W+AM+A +  +G   D I++ V+  + G  PN     AV+   + ++ +  G+   GF ++      +V +G  L+DM+ K +     A ++FD +   N V W+ MI   +     REA+  F +MVL         TL S+  AC +L +LS G+++H +AI+SG  L   V  +++ MYAKC   G +DD  + FD+M     +S++A+I+G ++N   A EA+ +F  M   G  +P+  T      AC +L+  + G      +   G  +++S+ N +I M+ K  ++   ++ F+ +  ++++S+N  + G   +     A      +    +     TF  LLS  ++ G + +G+
Sbjct:   52 MARDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVL-SGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSG--LVDDVECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGE 494          

Query: 1039 MREAMALFDEMVLRKEINPTP-VTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKM---NSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHG-FGTDTSICNVLIDMYSKC-GKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKH---WF--NAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEG--TGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRL--GYCAENSF-----VLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPI 2373
            +R A++  D M  R  I P   VT  S+L++C +  D   G+ VH   I+   + ++++ N+++S+Y+K G    A   F+ M     +D VS+SA+++    NG   +A+ +F      G  P+      V+ ACS+   +  G     + +  G F +D  +   LIDM+ K         +VFD+M   ++++W  MI      G    AI  F  M+ +G + D  T   + SAC+    ++ GK    W   + + +D   +    +  C  D     G + +      +M  +  V  W+AL+       N  L  E          +G    N    S+ + A G   D   V  +  GQ  K+    +    N +I  FV  D+            E+ LV       G C   +F     +L ++ E E        +  L+    + S+R G+ I
Sbjct:   42 LRGAVSALDLMA-RDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDDVECSLVDMYAKCSAD-----GSVDDCRKVFDRME-DHSVMSWTALITG--YMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPR-VGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQI 496          

Query:  217 RSKSLPQAKKIHQHLLK-NTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIP--QPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQM-QKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEM----------------------------------VLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLN-------TMVGNTILSMYAKCGIIDDAVRFFDKMNSK--DTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFD--PDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGT-DTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVE-INGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            + K++ Q K IHQ LL      L  TS L+      YI+   +  A  +    P     V  WN LIR+Y  NG   + ++L+  +      P  YT+PFV KAC  + ++  G   H  +   G  S+V+V  AL+ +Y++C  L++A+ VF  M   DVV+WN++I  ++  G     ++M  +M  + G  P+  T+V VLP  A     S GK +H F++   +   + +G  L+DMY+KC  +  A  +F  + VK+ V W+AM+  Y       +A+ LF++M                                  +L   I P  VTL S+L  C  +  L  G+ +HCYAIK   DL         MV N ++ MYAKC  +D A   FD ++ K  D V+++ +I G  Q+G A +AL +   M        P+  T+   L AC+ LAAL+ G   HAY++ +        + N LIDMY+KCG I+  R VFD M+ ++ ++W +++ GYG+HG G  A+  F  M   G K D VT + +L ACSHSG++ +G  +FN M   F ++P  EHY C+VDLLGRAG L  A   I++MP E    VW A L+ CR+H  +ELGE  ++KI        G+  LLSN+Y+  GRW D   +R   + +G+KK PGCSWVE I G    FV GD++HP + +I++ L + +  +K +GY  E  F L DV++EEK+ +L  HSEKLA+AY IL+   G  I +TKNLRVCGDCH A   ++ I   +II+RD +RFHHFK+G C+C  +W
Sbjct:   37 KCKTISQVKLIHQKLLSFGILTLNLTSHLIST----YISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLFGLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAYALRNQQNAVPLFVSNCLIDMYAKCGSISDARLVFDNMMAKNEVTWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVLYACSHSGMIDQGMEYFNRMKTVFGVSPGPEHYACLVDLLGRAGRLNAALRLIEEMPMEPPPVVWVAFLSCCRIHGKVELGEYAAEKITELASNHDGSYTLLSNLYANAGRWKDVTRIRSLMRHKGVKKRPGCSWVEGIKGTTTFFV-GDKTHPHAKEIYQVLLDHMQRIKDIGYVPETGFALHDVDDEEKDDLLFEHSEKLALAYGILTTPQGAAIRITKNLRVCGDCHTAFTYMSRIIDHDIILRDSSRFHHFKNGSCSCKGYW 850          

Query:  448 HLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKD--VVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIID-------------------------------DAVRFFDKMNSK----DTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVH-------GFGTDTSICNVLIDMYSKCGKINRGRQVFDRM--VTRDIISWNAMIVGYGIHGLGMAAISQFHHMLA--AGIKPDDVTFIGLLSACSHSGLVTEGK--HWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIE--LGEEVSKKIQGKGLEGTGNLVLL 2031
            H Y  +        + T PF+ K     + +   + IHQ   + G+ + + + + LI  Y   G L+ A ++ R     D  V  WN++I  +  +G  +  + +   M     +P+  T   V     + +++  G++ H  SL       V +G  L+ MYS+C+ ++ AR++FD + V + V W+++I +Y      + A+ +F  M       P  +TL ++L  C  L   S G+++HC+A+ S    N  VGN ++ MYAKCG++D                               DAVR F+KM  +    D V++SA ISG  Q G   EAL +   M  SG  P+  T++ VL  C+ + AL HG   H Y+I +       G G +  + N LIDMY+KC K++  R +FD +    RD+++W  MI GY  HG    A+     M       +P+  T    L AC+    +  GK  H + A+    N  P      C++D+  + G +++A +    M  + +V  W++L+    +H   E  LG     +  G  L+G   LV+L
Sbjct:   15 HQYIKVSLFSTSAPEITPPFIHKC----KTISQVKLIHQKLLSFGILT-LNLTSHLISTYISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLFGLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAY-ALRNQQNAVPLFVSN-CLIDMYAKCGSISDARLVFDNMMAKNEV-TWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVL 586          

Query:  295 FLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDV-EEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            F+   +  +Y     +  A +VFDE+P   ++ WN LI  Y+ +G +E A+ +Y++L  S + P  +T   VL A   L  ++ G+ +H  A   G+ S V V   L+ +Y K     +A+ VF  M  +D V++N MI G+    + +++++M ++       P+  T+ +VL        LS  K ++ + L+     E  +   L+D+Y+KC  +  AR +F++++ K+ V W+++I  Y+    + EAM LF  M++ +E     +T   ++   T+L DL  G+ +H   IKSG  ++  V N ++ MYAKCG + D+++ F  M + DTV+++ +IS CV+ G     L +   M+ S   PD+AT +  LP C+ LAA + G   H   +  G+ ++  I N LI+MYSKCG +    +VF+RM  RD+++W  MI  YG++G G  A+  F  M  +GI PD V FI ++ ACSHSGLV EG   F  M   + I P +EHY C+VDLL R+  +++A  FIQ MP + D  +W+++L ACR   ++E  E VS++I     +  G  +L SN Y+A+ +WD  + +R   K + + K+PG SW+E+   +H F  GD S PQS  I++ LE L   M + GY  +   V Q++ EEEEK R++  HSE+LAIA+ +L+  PG P+ V KNLRVCGDCH   K+I+ I  REI+VRD  RFH FKDG C+C D W
Sbjct:  142 FVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEE-QADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIVPDSVVFIAIIYACSHSGLVDEGLACFEKMKTHYKIDPMIEHYACVVDLLSRSQKISKAEEFIQAMPIKPDASIWASVLRACRTSGDMETAERVSRRIIELNPDDPGYSILASNAYAALRKWDKVSLIRKSLKDKHITKNPGYSWIEVGKNVHVFSSGDDSAPQSEAIYKSLEILYSLMAKEGYIPDPREVSQNLEEEEEKRRLICGHSERLAIAFGLLNTEPGTPLQVMKNLRVCGDCHEVTKLISKIVGREILVRDANRFHLFKDGTCSCKDRW 882          

Query:  220 SKSLPQAKKIHQHLLKNTTRLKD--TSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMI---VGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYS 2046
            S +L + ++IH  ++       D  +  L++K +H     + + +  RV    P  +V LWN +IRA++ NG F  A+  Y  L +S V P KYT+P V+KAC+GL   E G  +++    +G  SD++V  AL+D+Y++ G L  A+ VF  M  +D+V+WN++I+G+S HG Y++ +++  +++ +   P++ T+ +VLP       + QG+ +HGF+L+  ++  VV+  GL+ MY K +    ARR+FD +DV++ V ++ MI  Y+  + + E++ +F E +   +  P  +T+ S+LRAC  L DLS  + ++ Y +K+GF L + V N ++ +YAKCG +  A   F+ M  KDTVS+++IISG +Q+G   EA+ +F  M +     D  T + ++   + LA L+ G   H+  I  G   D S+ N LIDMY+KCG++    ++F  M T D ++WN +I   V +G    G+   +Q   M  + + PD  TF+  L  C+       GK   +     F     ++    ++++  + G L  +    ++M    DV  W+ ++ A  ++   E   E    ++  G+    ++V ++ IY+
Sbjct:   17 SSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVS---PAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENL--DQFKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQ---MRKSEVVPDMATFLVTLPMCASLAAKRLGKE-IHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMS-RRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIV-PDSVVFIAIIYA 619          

Query:  487 TKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML-YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWF-NAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQ 1992
            T+ + PF+ +A S    L   R IH    +LGL S  +    LID Y+     A + +VFR +   K+V  WN++I  FS +GL+ + ++   +++++  SP+  T  +V+   A       G  ++   L      ++ +G  L+DMYS+   +  AR++FD + V++ V W+++I  Y       EA+ ++ E+     I P   T+ S+L A   L  + +G+ +H +A+KSG +   +V N +++MY K     DA R FD+M+ +D+VSY+ +I G ++    +E++ +F    L  F PDL T+  VL AC HL  L      + Y +  GF  ++++ N+LID+Y+KCG +   R VF+ M  +D +SWN++I GY   G  M A+  F  M+    + D +T++ L+S  +    +  GK    N +     I   + +   ++D+  + G + ++      M    D   W+ +++AC    +   G +V+ +++
Sbjct:    3 TRVSSPFISRALSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHEL-KNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLE-NLDQFKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSN--ALIDMYAKCGEVGDSLKIFSSMG-TGDTVTWNTVISACVRFGDFATGLQVTTQMR 501          

Query:  385 VILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQA-NALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +I  N  +  Y  +G +   +  + D+++S V+  + T+  +L     + +L  G+++H  A  LGL   + V  +LI++Y K      A+TVF  M  +D+++WN++IAG + +GL  + + + +Q+ + G  P+  T+ +VL   +     LS  K +H  +++ +   +  + T L+D YS+ +C+  A  +F+  +  + V W+AM+  Y       + + LF  M  + E      TL ++ + C  L  +++G++VH YAIKSG+DL+  V + IL MY KCG +  A   FD +   D V+++ +ISGC++NG  + A  +F  M+L G  PD  T+  +  A S L AL+ G   HA ++      D  +   L+DMY+KCG I+    +F R+   +I +WNAM+VG   HG G   +  F  M + GIKPD VTFIG+LSACSHSGLV+E      +M  D+ I P +EHY C+ D LGRAG + +A   I+ M  EA   ++  LLAACRV  + E G+ V+ K+       +   VLLSN+Y+A  +WD+    R   KG  +KK PG SW+E+   IH FV  D+S+ Q+  I+ K+++++ D+K+ GY  E  F L DVEEEEKER L YHSEKLA+A+ +LS  P  PI V KNLRVCGDCH A+K I  +  REI++RD  RFH FKDGIC+C D+W
Sbjct:  280 IIFRNKGLSEYLHSGQYSALLKCFADMVESDVECDQVTFILMLATAVKVDSLALGQQVHCMALKLGLDLMLTVSNSLINMYCKLRKFGFARTVFDNMSERDLISWNSVIAGIAQNGLEVEAVCLFMQLLRCGLKPDQYTMTSVLKAASSLPEGLSLSKQVHVHAIKINNVSDSFVSTALIDAYSRNRCMKEAEILFERHNF-DLVAWNAMMAGYTQSHDGHKTLKLFALMHKQGE-RSDDFTLATVFKTCGFLFAINQGKQVHAYAIKSGYDLDLWVSSGILDMYVKCGDMSAAQFAFDSIPVPDDVAWTTMISGCIENGEEERAFHVFSQMRLMGVLPDEFTIATLAKASSCLTALEQGRQIHANALKLNCTNDPFVGTSLVDMYAKCGSIDDAYCLFKRIEMMNITAWNAMLVGLAQHGEGKETLQLFKQMKSLGIKPDKVTFIGVLSACSHSGLVSEAYKHMRSMHGDYGIKPEIEHYSCLADALGRAGLVKQAENLIESMSMEASASMYRTLLAACRVQGDTETGKRVATKLLELEPLDSSAYVLLSNMYAAASKWDEMKLARTMMKGHKVKKDPGFSWIEVKNKIHIFVVDDRSNRQTELIYRKVKDMIRDIKQEGYVPETDFTLVDVEEEEKERALYYHSEKLAVAFGLLSTPPSTPIRVIKNLRVCGDCHNAMKYIAKVYNREIVLRDANRFHRFKDGICSCGDYW 990          

Query:  214 IRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGP-----FERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHL-AALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK--HWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEE 1974
            I S  L   K  H  +L  T       FL+  +  +Y  C  +  A RVFD++P   ++ WN ++ AYA +        ++A  L+  L Q  V  ++ T   +LK C     + A    H +A  +GL  D +V  AL+++Y K G + E + +F  M Y+DVV WN M+  +   G  ++ I +      +G +PN  T+  +       +   Q K+    +   S+S  +    GL +     Q  A  +            C++ M+ + V CD                      VT   +L    K+  L+ G++VHC A+K G DL   V N++++MY K      A   FD M+ +D +S++++I+G  QNG   EA+ +F  +   G  PD  TM  VL A S L   L      H ++I     +D+ +   LID YS+   +     +F+R    D+++WNAM+ GY     G   +  F  M   G + DD T   +   C     + +GK  H + A+   +++   +   I  +D+  + G ++ A      +P   DV  W+ +++ C     IE GEE
Sbjct:   50 ITSSDLMLGKCTHARIL--TFEENPERFLINNLISMYSKCGSLTYARRVFDKMPDRDLVSWNSILAAYAQSSECVVENIQQAFLLFRILRQDVVYTSRMTLSPMLKLCLHSGYVWASESFHGYACKIGLDGDEFVAGALVNIYLKFGKVKEGKVLFEEMPYRDVVLWNLMLKAYLEMGFKEEAIDLSSAFHSSGLNPNEITLRLLARISGDDSDAGQVKSFANGNDASSVSEIIFRNKGLSEYLHSGQYSALLK------------CFADMVESDVECDQ---------------------VTFILMLATAVKVDSLALGQQVHCMALKLGLDLMLTVSNSLINMYCKLRKFGFARTVFDNMSERDLISWNSVIAGIAQNGLEVEAVCLFMQLLRCGLKPDQYTMTSVLKAASSLPEGLSLSKQVHVHAIKINNVSDSFVSTALIDAYSRNRCMKEAEILFERH-NFDLVAWNAMMAGYTQSHDGHKTLKLFALMHKQGERSDDFTLATVFKTCGFLFAINQGKQVHAY-AIKSGYDLDLWVSSGI--LDMYVKCGDMSAAQFAFDSIPVPDDV-AWTTMISGC-----IENGEE 599          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQG----KAMHG 867
            TC    ++ Q K++H + +K+   L    ++   +  +Y+ C  +  A   FD IP P  + W  +I     NG  ERA H++  +   GV P ++T   + KA S L ALE GR+IH +A  L   +D +V T+L+D+YAKCG + +A  +F+ +   ++ AWNAM+ G + HG   +T+Q+  QM+  G  P+  T + VL   + +  +S+     ++MHG
Sbjct:  526 TCGFLFAINQGKQVHAYAIKSGYDLD--LWVSSGILDMYVKCGDMSAAQFAFDSIPVPDDVAWTTMISGCIENGEEERAFHVFSQMRLMGVLPDEFTIATLAKASSCLTALEQGRQIHANALKLNCTNDPFVGTSLVDMYAKCGSIDDAYCLFKRIEMMNITAWNAMLVGLAQHGEGKETLQLFKQMKSLGIKPDKVTFIGVLSACSHSGLVSEAYKHMRSMHG 747          

Query:  775 AGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYV-----ICDSMREAMALFDEMVLRKEINPTP-VTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATM 1413
            + +S ++S     L     ++ L  GK  H   L    + E  L   L+ MYSKC  + YARR+FD +  ++ V W++++ AY      + +++++A  LF   +LR+++  T  +TL  +L+ C     +      H YA K G D +  V   ++++Y K G + +    F++M  +D V ++ ++   ++ G+ +EA+ +      SG +P+  T+
Sbjct:   33 SSSSSSSSQWFGFLRNAITSSDLMLGKCTHARILTFEENPERFLINNLISMYSKCGSLTYARRVFDKMPDRDLVSWNSILAAYAQSSECVVENIQQAFLLF--RILRQDVVYTSRMTLSPMLKLCLHSGYVWASESFHGYACKIGLDGDEFVAGALVNIYLKFGKVKEGKVLFEEMPYRDVVLWNLMLKAYLEMGFKEEAIDLSSAFHSSGLNPNEITL 249          

Query:  508 VLKACSGLQALEAGREIHQHAKALGLASDVYVCTALID---LYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLR-------------------------------RSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAY--SIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +L  C  LQ+L   R IH     +GL +  Y  + LI+   L     GL  A +VF+ +   +++ WN M  G +L       +++ V M   G  PN+ T   VL + A++ A  +G+ +HG  L+                               +S   +VV  T L+  Y+    I  A+++FD I VK+ V W+AMI  Y    + +EA+ LF +M ++  + P   T+ +++ AC +   +  GR+VH +    GF  N  + N ++ +Y+KCG ++ A   F+++  KD +S++ +I G       KEALL+F  M  SG  P+  TM+ +LPAC+HL A+  G   H Y    + G    +S+   LIDMY+KCG I    QVF+ ++ + + SWNAMI G+ +HG   A+   F  M   GI+PDD+TF+GLLSACSHSG++  G+H F  M++D+ +TP++EHY CM+DLLG +G   EA   I  M  E D  +W +LL AC++H N+ELGE  ++ +     E  G+ VLLSNIY++ GRW++ A  R     +G+KK PGCS +EI+ ++H F+ GD+ HP++ +I+  LEE+ V +++ G+  + S VLQ++EEE KE  L +HSEKLAIA+ ++S +PG  + + KNLRVC +CH A K+I+ I KREII RD TRFHHF+DG+C+C D+W
Sbjct:   39 LLHNCKTLQSL---RIIHAQMIKIGLHNTNYALSKLIEFCILSPHFEGLPYAISVFKTIQEPNLLIWNTMFRGHALSSDPVSALKLYVCMISLGLLPNSYTFPFVLKSCAKSKAFKEGQQIHGHVLKLGCDLDLYVHTSLISMYVQNGRLEDAHKVFDKSPHRDVVSYTALIKGYASRGYIENAQKLFDEIPVKDVVSWNAMISGYAETGNYKEALELFKDM-MKTNVRPDESTMVTVVSACAQSGSIELGRQVHLWIDDHGFGSNLKIVNALIDLYSKCGELETACGLFERLPYKDVISWNTLIGGYTHMNLYKEALLLFQEMLRSGETPNDVTMLSILPACAHLGAIDIGRWIHVYIDKRLKGVTNASSLRTSLIDMYAKCGDIEAAHQVFNSILHKSLSSWNAMIFGFAMHGRADASFDLFSRMRKIGIQPDDITFVGLLSACSHSGMLDLGRHIFRTMTQDYKMTPKLEHYGCMIDLLGHSGLFKEAEEMINMMEMEPDGVIWCSLLKACKMHGNVELGESFAENLIKIEPENPGSYVLLSNIYASAGRWNEVAKTRALLNDKGMKKVPGCSSIEIDSVVHEFIIGDKFHPRNREIYGMLEEMEVLLEKAGFVPDTSEVLQEMEEEWKEGALRHHSEKLAIAFGLISTKPGTKLTIVKNLRVCRNCHEATKLISKIYKREIIARDRTRFHHFRDGVCSCNDYW 741          

Query:  223 KSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVD---LASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVF--------------------RGML-----------YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIK--SGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK 1767
            K+L   + IH  ++K    L +T++ L K+    I     +    A  VF  I +P++++WN + R +A +     A+ LY  ++  G+ P  YT+PFVLK+C+  +A + G++IH H   LG   D+YV T+LI +Y + G L +A  VF                    RG +            KDVV+WNAMI+G++  G Y + +++   M K    P+ ST+V V+   AQ+ ++  G+ +H +         + +   L+D+YSKC  +  A  +F+ +  K+ + W+ +IG Y   +  +EA+ LF EM LR    P  VT+ SIL AC  L  +  GR +H Y  K   G    + +  +++ MYAKCG I+ A + F+ +  K   S++A+I G   +G A  +  +F  M+  G  PD  T VG+L ACSH   L  G         H F T T                       D  +T  +  +  MI   G  GL   A    + M    ++PD V +  LL AC   G V  G+
Sbjct:   44 KTLQSLRIIHAQMIK--IGLHNTNYALSKLIEFCILSPHFEGLPYAISVFKTIQEPNLLIWNTMFRGHALSSDPVSALKLYVCMISLGLLPNSYTFPFVLKSCAKSKAFKEGQQIHGHVLKLGCDLDLYVHTSLISMYVQNGRLEDAHKVFDKSPHRDVVSYTALIKGYASRGYIENAQKLFDEIPVKDVVSWNAMISGYAETGNYKEALELFKDMMKTNVRPDESTMVTVVSACAQSGSIELGRQVHLWIDDHGFGSNLKIVNALIDLYSKCGELETACGLFERLPYKDVISWNTLIGGYTHMNLYKEALLLFQEM-LRSGETPNDVTMLSILPACAHLGAIDIGRWIHVYIDKRLKGVTNASSLRTSLIDMYAKCGDIEAAHQVFNSILHKSLSSWNAMIFGFAMHGRADASFDLFSRMRKIGIQPDDITFVGLLSACSHSGMLDLGR--------HIFRTMTQ----------------------DYKMTPKLEHYGCMIDLLGHSGLFKEAEEMINMM---EMEPDGVIWCSLLKACKMHGNVELGE 558          

Query:  208 TCIRSKSLPQAKKIHQHLLK------------------NTTRLKDTSFLLEKVAHL-----------YITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR--SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGN--TILSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGCVQNG 1341
            +C +SK+  + ++IH H+LK                     RL+D   + +K  H            Y +   ++ A ++FDEIP   V+ WN +I  YA  G ++ A+ L+ D++++ V+P + T   V+ AC+   ++E GR++H      G  S++ +  ALIDLY+KCG L  A  +F  + YKDV++WN +I G++   LY + + +  +M ++G +PN  T++++LP  A   A+  G+ +H +  +R   ++    L T L+DMY+KC  I  A ++F++I  K+   W+AMI  + +      +  LF  M  +  I P  +T   +L AC+    L  GR +    +   + +   + +   ++ +    G+  +A    + M  + D V + +++  C  +G
Sbjct:  143 SCAKSKAFKEGQQIHGHVLKLGCDLDLYVHTSLISMYVQNGRLEDAHKVFDKSPHRDVVSYTALIKGYASRGYIENAQKLFDEIPVKDVVSWNAMISGYAETGNYKEALELFKDMMKTNVRPDESTMVTVVSACAQSGSIELGRQVHLWIDDHGFGSNLKIVNALIDLYSKCGELETACGLFERLPYKDVISWNTLIGGYTHMNLYKEALLLFQEMLRSGETPNDVTMLSILPACAHLGAIDIGRWIHVYIDKRLKGVTNASSLRTSLIDMYAKCGDIEAAHQVFNSILHKSLSSWNAMIFGFAMHGRADASFDLFSRM-RKIGIQPDDITFVGLLSACSHSGMLDLGRHIF-RTMTQDYKMTPKLEHYGCMIDLLGHSGLFKEAEEMINMMEMEPDGVIWCSLLKACKMHG 552          

Query:  463 LLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLH-GLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAID-VKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKE--INPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGD-QSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +L  G+ P ++T+PFVLKACS L+    GREIH   K L L S+VYV TAL+D YAKCG L +A+ VF  M  +DVVAWN+MI+GFSLH G YD+  ++LVQMQ    SPN+STIV VLP VAQ N+L  GK +HGF +RR   G+VV+GTG+LD+Y KCQCI YARRIFD +  VKNEV WSAM+GAYV+CD MREA+ LF ++++ K+  I  + VTL +++R C  LTDLS G  +HCYAIKSGF L+ MVGNT+LSMYAKCGII+ A+RFF++M+ +D VS++AIISG VQNG ++E L +F  MQLSG +P+ AT+  VLPAC+HLA L +G+C H Y+I+ GF  DT ICN LIDMY+KCGKI+  R+VFDRM  R I+SWN MI+ YGIHG+G+ A+  F +M + G+KPDDVTFI L+SACSHSGLV EGK+WFNAM++DF I PRMEHY CMVDLL RAG   E H FI+KMP E DVRVW ALL+ACRV+ N+ELGE VSKKIQ  G E TGN VLLSN+YSAVGRWDDAA VR  QK QG +KSPGCSW+EI+G++H F+GG  +SHPQ  QI  KL+ELLV+MKRLGY AE+S+V QDVEEEEKER+LLYHSEKLAIA+ ILSL P K I+VTKNLRVCGDCH AIK I+L+TKR+I VRD +RFHHFKDGICNC DFW
Sbjct:    1 MLGYGITPNRFTFPFVLKACSALKEASEGREIHCDIKRLRLESNVYVSTALVDFYAKCGCLDDAKEVFDKMHKRDVVAWNSMISGFSLHEGSYDEVARLLVQMQN-DVSPNSSTIVGVLPAVAQVNSLRHGKEIHGFCVRRGFVGDVVVGTGILDVYGKCQCIDYARRIFDMMGIVKNEVTWSAMVGAYVVCDFMREALELFCQLLMLKDDVIVLSAVTLATVIRVCANLTDLSTGTCLHCYAIKSGFVLDLMVGNTLLSMYAKCGIINGAMRFFNEMDLRDAVSFTAIISGYVQNGNSEEGLRMFLEMQLSGINPEKATLASVLPACAHLAGLHYGSCSHCYAIICGFTADTMICNALIDMYAKCGKIDTARKVFDRMHKRGIVSWNTMIIAYGIHGIGLEALLLFDNMQSEGLKPDDVTFICLISACSHSGLVAEGKYWFNAMTQDFGIIPRMEHYACMVDLLSRAGLFKEVHSFIEKMPLEPDVRVWGALLSACRVYKNVELGEGVSKKIQKLGPESTGNFVLLSNMYSAVGRWDDAAQVRFTQKEQGFEKSPGCSWIEISGVVHTFLGGGYRSHPQLTQISNKLDELLVEMKRLGYQAESSYVFQDVEEEEKERVLLYHSEKLAIAFGILSLSPDKHIIVTKNLRVCGDCHTAIKFISLVTKRDITVRDASRFHHFKDGICNCGDFW 690          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWN-GPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGM-LYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSP---NASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACG-HAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRM-VTRDIISWNAMI 1623
            C   K   + ++IH  + +   RL+   ++   +   Y  C  +D A  VFD++ +  V+ WN +I  ++ + G ++    L    +Q+ V P   T   VL A + + +L  G+EIH      G   DV V T ++D+Y KC  +  A+ +F  M + K+ V W+AM+  + +     + +++  Q+          +A T+  V+   A    LS G  +H ++++     ++++G  LL MY+KC  I  A R F+ +D+++ V ++A+I  YV   +  E + +F EM L   INP   TL S+L AC  L  L  G   HCYAI  GF  +TM+ N ++ MYAKCG ID A + FD+M+ +  VS++ +I     +G   EALL+F +MQ  G  PD  T + ++ ACSH   +  G    +A +   G          ++D+ S+ G         ++M +  D+  W A++
Sbjct:   20 CSALKEASEGREIHCDIKR--LRLESNVYVSTALVDFYAKCGCLDDAKEVFDKMHKRDVVAWNSMISGFSLHEGSYDEVARLLVQ-MQNDVSPNSSTIVGVLPAVAQVNSLRHGKEIHGFCVRRGFVGDVVVGTGILDVYGKCQCIDYARRIFDMMGIVKNEVTWSAMVGAYVVCDFMREALELFCQLLMLKDDVIVLSAVTLATVIRVCANLTDLSTGTCLHCYAIKSGFVLDLMVGNTLLSMYAKCGIINGAMRFFNEMDLRDAVSFTAIISGYVQNGNSEEGLRMFLEMQL-SGINPEKATLASVLPACAHLAGLHYGSCSHCYAIICGFTADTMICNALIDMYAKCGKIDTARKVFDRMHKRGIVSWNTMIIAYGIHGIGLEALLLFDNMQSEGLKPDDVTFICLISACSHSGLVAEGKYWFNAMTQDFGIIPRMEHYACMVDLLSRAGLFKEVHSFIEKMPLEPDVRVWGALL 493          

Query:  193 HIYS-TTCIRSKSLPQAKKIHQ---HLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            HIY     I  +    +K++HQ    ++KN   L + +    K+  L+     +  ASRVF+ I      L++ +++ YA +   + A+  +  +    V+P  Y + ++LK C     L+ G+EIH      G + +++  T ++++YAKC  + +A  +F  M  +D+V WN MI+G++ +G     + ++++M + G  P++ TIV++LP VA    L  G A+HG+ LR      V + T L+DMYSKC  ++ AR IFD +D +  V W++MI  YV       AM +F +M L + + PT VT+   L AC  L DL RG+ VH    +   D +  V N+++SMY+KC  +D A   F  + +K  VS++A+I G  QNG   EAL  F  MQ     PD  TMV V+PA + L+  +     H   I      +  +   L+DMY+KCG I+  R++FD M  R +I+WNAMI GYG HGLG  ++  F  M    IKP+D+TF+  LSACSHSGLV EG  +F +M +D+ I P M+HY  MVDLLGRAG L +A  FIQKMP +  + V+ A+L AC++H N++LGE+ + +I     +  G  VLL+NIY+    W   A VR   +  GL+K+PGCS VEI   +H F  G  SHPQS +I+  LE L+ +++  GY  + + +  DVE++ K ++L  HSEKLAIA+ +L+   G PI + KNLRVCGDCH A K I+L+T REIIVRD+ RFH FKDG+C+C D+W
Sbjct:   37 HIYKHPAAILLELCTSSKEVHQILPQIIKNG--LYNETLFQTKLISLFCKYGNLTEASRVFEPIEDKFDALYHTMLKGYAKSSSLDSALSFFSRMKHDSVRPVVYNFTYLLKLCGDNSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPERDLVCWNTMISGYAQNGFAKVALMLVLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKM-LDEGVQPTNVTVMGALHACADLGDLERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEEGLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQKMPIKPGITVYGAMLGACKIHKNVDLGEKAAFEIFKLNPDDGGYHVLLANIYATASMWGKVAKVRTIMEKSGLQKTPGCSLVEIGNEVHSFYSGTTSHPQSKKIYSYLETLVDEIRAAGYVPDTNSI-HDVEDDVKVQLLNTHSEKLAIAFGLLNTSTGTPIHIRKNLRVCGDCHNATKYISLVTGREIIVRDMHRFHLFKDGVCSCGDYW 812          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            C  +K L   K++H  ++   T      F+   +  LY  C     A  +FD IP  SV+ WN L   Y  +     A+ L++D++ SG++P +++   ++  C+GL+    GR+IH +   LG  SD +   AL+D+YAK G L +A +VF  +   D+V+WNA+IAG  LH  +   +++L +M K+G  PN  T+ + L   A       G+ +H   ++  +  +  LG GL+DMYSKC  +  AR +F  +  ++ + W+A+I  +   +   EA +LF  ++  + I     TL ++L++   L      R++H  ++KSGF+ +  V N+++  Y KCG ++DA R F++  + D V ++++++   Q+G  +EAL ++  MQ  G  PD      +L AC+ L+A + G   H + +  GF +D    N L++MY+KCG I      F R+  R I+SW+AMI G   HG G  A+  F  ML  G+ P+ +T + +L AC+H+GLV E KH+FN+M   F I P  EHY CM+DLLGRAG L  A   + KMPF+A+  VW ALL A R+H NI+LGE+ ++ +     E +G  VLL+NIY++VG WD  A VR   K   +KK PG SW+E+   ++ F+ GD+SH +S +I+ KL+EL   +K+ GY       L DVE  EKE++L +HSEKLA+A+ +++  PG PI V KNLR+C DCH  +K I+ I  REIIVRD  RFHHF+DG C+C ++W
Sbjct:   92 CTVTKDLVLGKQVHGIVV--VTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFP-LMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGFEFDNYVVNSLIDTYGKCGHVEDATRVFEESPTVDLVLFTSLVTAYAQDGQGEEALRLYLEMQDRGIKPDSFVCSSLLNACASLSAYEQGKQVHVHILKFGFMSDIFAGNSLVNMYAKCGSIEDASCAFSRIPVRGIVSWSAMIGGLAQHGYGKEALQLFKQMLKVGVPPNHITLVSVLCACNHAGLVAEAKHYFNSMKILFGIEPMQEHYACMIDLLGRAGKLEAAMELVNKMPFQANALVWGALLGAARIHKNIDLGEQAAEMLLALEPEKSGTHVLLANIYASVGMWDKVARVRRLMKDGKVKKEPGMSWLEVKDKVYTFIVGDRSHSRSTEIYAKLDELSDLLKKAGYVPMVEIDLHDVERSEKEQLLYHHSEKLAVAFGLIATPPGAPIRVKKNLRICFDCHTVLKFISKIVSREIIVRDTNRFHHFRDGSCSCGEYW 858          

Query:  310 VAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKH------WFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            + +LY  C     A ++ D   +P ++ W+ LI  Y+ NG  + A+  +Y++   G+K  ++ +P VLKAC+  + L  G+++H      G  SD +V  +L+ LYAKCGG  +A+++F  +  + VV+WNA+ + +    ++ + + +   M  +G  PN  ++ +++          QG+ +HG+ ++     +      L+DMY+K   +  A  +FD I   + V W+A+I   V+ +    A+ L  EM  +  + P   TL S L+AC  +     GR++H   IK     ++ +G  ++ MY+KC  +DDA   F  M  +D ++++A+ISG  QN   +EA  +F  M   G   +  T+  VL + + L A       HA S+  GF  D  + N LID Y KCG +    +VF+   T D++ + +++  Y   G G  A+  +  M   GIKPD      LL+AC+      +GK        F  MS+ F           +V++  + G + +A     ++P    V  WSA++     H
Sbjct:   22 LVNLYSKCQLFGYARKLLDRSTEPDLVSWSALISGYSQNGFCQEAVLAFYEMHLLGIKCNEFAFPSVLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREM-NKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFPLMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGFEFDNYVVNSLIDTYGKCGHVEDATRVFEESPTVDLVLFTSLVTAYAQDGQGEEALRLYLEMQDRGIKPDSFVCSSLLNACASLSAYEQGKQVHVHILKFGFMSDIFAGN-------SLVNMYAKCGSIEDASCAFSRIPVRGIVS-WSAMIGGLAQH 565          

Query:  553 EIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLS--ACSHSGLVTEGKHWFNAMSEDFNITPRMEHYI--CMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLE 2007
            EIH      GL+ D  +   L++LY+KC     A+ +       D+V+W+A+I+G+S +G   + +    +M   G   N     +VL        L  GK +HG  +      +  +   L+ +Y+KC     AR +FDAI  ++ V W+A+   YV  D   EA++LF +MVL   I P   +L S++  CT L D  +GR++H Y IK G+D +    N ++ MYAK GI++DA   FD++   D VS++AII+GCV + Y   AL +   M  SG  P++ T+   L AC+ +A  + G   H+  I    G+D+ +   LIDMYSKC  ++  R VF  M  RD+I+WNA+I G+  +     A S F  M   GI  +  T   +L   A   +  +    H  +  S         ++Y+   ++D  G+ G + +A    ++ P   D+ ++++L+ A       E    +  ++Q +G++
Sbjct:    2 EIHARVIKFGLSQDPKIRNYLVNLYSKCQLFGYARKLLDRSTEPDLVSWSALISGYSQNGFCQEAVLAFYEMHLLGIKCNEFAFPSVLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVL-SGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFPLMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGF-----EFDNYVVNSLIDTYGKCGHVEDATRVFEESP-TVDLVLFTSLVTAYAQDGQGEEALRLYLEMQDRGIK 483          

Query: 1165 VHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAM------SEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSA 2049
            +H   IK G   +  + N ++++Y+KC +   A +  D+    D VS+SA+ISG  QNG+ +EA+L F+ M L G   +      VL AC+    L  G   H   +V GF +D  + N L+ +Y+KCG     R +FD +  R ++SWNA+   Y    +   A+S FH M+ +GI+P++ +   +++ C+      +G+     +      S+ F+          +VD+  + G L +A     ++  + D+  W+A++A C +H       E+ +++   G+    N+  LS+   A
Sbjct:    3 IHARVIKFGLSQDPKIRNYLVNLYSKCQLFGYARKLLDRSTEPDLVSWSALISGYSQNGFCQEAVLAFYEMHLLGIKCNEFAFPSVLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSAN-------ALVDMYAKVGILEDASSVFDEIA-KPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGM--CPNMFTLSSALKA 293          

Query:  223 KSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            KSL   KK+H  +  +   +   S L  K+  +Y+TC  +     +FD+I    V LWNL++  Y   G F+ ++ L+  +L  GV+   +T   VLK  + L +++ G+ +H     LGL S   V  +LI  Y K   +  A+ +F  +  +DV++WN+MI+G+  +G  +  +++  +M   G   + +T+V++L   A    +S G+A+HG  ++  +  +      LLDMY+KC  +  A  +FD + V+  V W+++I AY       EA+ LF EM  R+ ++P   T+ ++L AC     L  G+ VH Y  ++    N  V N ++ MYAKCG ++DA   F +M  KD +S++ +I G  +N    EAL +F  M L    PD  T+  +LPAC+ LA+L  G   H + + +GF +D  + N L+DMY KCG     R +FD + T+D+I+W  MI GYG+HG G  AI+ F+ M  AGI+PD+V+FI +L ACSHSGL+ EG  +FN M ++ N+ P++EHY C+VDLL R+G LA A+ FI+ MP E D  +W ALL+ CR+H++++L E+V++ +     E TG  VLL+N Y+   +W++   +R K   +GLKK+PGCSW+E+   +H F+ G+ SHPQ+ +I   L+ L   MK  GY  +  + L + +  +KE  L  HSEKLA+A+ IL+L P + I V+KNLRVCGDCH   K I+    REI++RD  RFHHFKDG+C C  FW
Sbjct:   17 KSLQDGKKVHSFICSSGISID--SVLGSKLVFMYVTCGDLREGRLIFDKIRNEKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLGVEVNSHTVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKMLYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMD-REGVSPDIFTITTVLHACACNGSLENGKDVHNYIRENDMQSNIFVCNALMDMYAKCGSMEDANSVFLEMPVKDIISWNTMIGGYSKNSLPNEALSLFGDMVLE-MKPDGTTLACILPACASLASLDRGKEVHGHILRNGFFSDQQVANALVDMYVKCGVPVLARLLFDMIPTKDLITWTVMIAGYGMHGFGNNAITTFNEMRQAGIEPDEVSFISILYACSHSGLLDEGWRFFNVMQDECNVKPKLEHYACIVDLLARSGKLAMAYKFIKSMPIEPDATIWGALLSGCRIHHDVKLAEKVAEHVFELEPENTGYYVLLANTYAEAEKWEEVKKLRQKIGRRGLKKNPGCSWIEVKSKVHIFLAGNSSHPQAKKIEVLLKRLRSKMKEEGYFPKTRYALINADSLQKETALCGHSEKLAMAFGILNLPPARTIRVSKNLRVCGDCHEMAKFISKTLGREIVLRDSNRFHHFKDGVCCCRGFW 778          

Query:  508 VLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWF-NAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            +L+  + L++L+ G+++H    + G++ D  + + L+ +Y  CG L E + +F  +  + V  WN M+ G++  G + +++ +  QM   G   N+ T+  VL   A   ++ +GK +HGF L+  L     +   L+  Y K + +  AR++FD +  ++ + W++MI  YV      + + LF +M L   ++    T+ SIL+AC    D+S GR VH   +K+     T   NT+L MYAKCG++D A+  FD M+ +  V+++++I+   + G + EA+ +FH M   G  PD+ T+  VL AC+   +L++G   H Y   +   ++  +CN L+DMY+KCG +     VF  M  +DIISWN MI GY  + L   A+S F  M+   +KPD  T   +L AC+    +  GK    + +   F    ++ +   +VD+  + G    A +    +P + D+  W+ ++A   +H
Sbjct:    9 ILQLSAELKSLQDGKKVHSFICSSGISIDSVLGSKLVFMYVTCGDLREGRLIFDKIRNEKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLGVEVNSHTVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKM-LYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMDREGVSPDIFTITTVLHACACNGSLENGKDVHNYIRENDMQSNIFVCNALMDMYAKCGSMEDANSVFLEMPVKDIISWNTMIGGYSKNSLPNEALSLFGDMVLE-MKPDGTTLACILPACASLASLDRGKEVHGHILRNGFFSDQQVAN--ALVDMYVKCGVPVLARLLFDMIPTK-DLITWTVMIAGYGMH 485          

Query:  799 TIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMV-LRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALL 1932
            T  ++L   A+  +L  GK +H F     +S + VLG+ L+ MY  C  +   R IFD I  +    W+ M+  Y      +E+++LF +M+ L  E+N    T+  +L+    L  +  G+ VH + +K G      V N++++ Y K   +D A + FD+++++D +S++++ISG V NG++++ + +F  M   G D DLATMV +L AC++   +  G   H   +       T+ CN L+DMY+KCG ++    VFD M  R +++W ++I  Y   GL   AI  FH M   G+ PD  T   +L AC+ +G +  GK   N + E+     +   ++C  ++D+  + G + +A+    +MP + D+  W+ ++
Sbjct:    5 TCCSILQLSAELKSLQDGKKVHSFICSSGISIDSVLGSKLVFMYVTCGDLREGRLIFDKIRNEKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLGVEVNSH--TVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKMLYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMDREGVSPDIFTITTVLHACACNGSLENGKDVHNYIREN---DMQSNIFVCNALMDMYAKCGSMEDANSVFLEMPVK-DIISWNTMI 379          

Query: 1105 TLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK-----------HW----FNAMSEDFNITPRMEHYICMVDLL---------------GRAGFLAEAHVFIQKMPFEA---DVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVL---LSNIYSAVGRWDDA 2070
            T  SIL+   +L  L  G++VH +   SG  +++++G+ ++ MY  CG + +    FDK+ ++    ++ +++G  + G  KE++ +F  M   G + +  T+  VL   + L +++ G   H + +  G G+  ++ N LI  Y K  +++  R++FD +  RD+ISWN+MI GY  +G     +  F  ML  G+  D  T + +L AC++ G V+ G+           HW     N + + +     ++  I + DL+                R G   EA     +M  E    D+   + +L AC  + ++E G++V   I+   ++   N+ +   L ++Y+  G  +DA
Sbjct:    5 TCCSILQLSAELKSLQDGKKVHSFICSSGISIDSVLGSKLVFMYVTCGDLREGRLIFDKIRNEKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLGVEVNSHTVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKMLYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMDREGVSPDIFTITTVLHACACNGSLENGKDVHNYIRENDMQ--SNIFVCNALMDMYAKCGSMEDA 360          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAG---REIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGM-LYKDVVAWNAMIAGFSLH 729
            C    SL + K++H H+L+N         +   +  +Y+ C    LA  +FD IP   +I W ++I  Y  +G    AI  + ++ Q+G++P + ++  +L ACS    L+ G     + Q    +    + Y C  ++DL A+ G LA A    + M +  D   W A+++G  +H
Sbjct:  416 CASLASLDRGKEVHGHILRN--GFFSDQQVANALVDMYVKCGVPVLARLLFDMIPTKDLITWTVMIAGYGMHGFGNNAITTFNEMRQAGIEPDEVSFISILYACSHSGLLDEGWRFFNVMQDECNVKPKLEHYAC--IVDLLARSGKLAMAYKFIKSMPIEPDATIWGALLSGCRIH 588          

Query:  295 FLLEKVAHLYITCNQVDLASRVFDEIPQPS-VILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDM-KRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            F+   +  +Y  CN +  A ++FD + + + V+ WN +I AY+ NG    A+ L+ ++ ++GV    YT    L+AC      + G EIH          DVYV  AL+ ++ + G ++ A  +F  +  KD + WN+MIAGF+ +GLY++ +Q    +Q A   P+  +++++L    +   L  GK +H ++++  L   + +G  L+DMYSKC C+AYA  +FD +  K+ + W+ +I AY   +   EA+ L  + V  K ++   + +GS L AC+ L  LS  + VH Y +K G   + M+ N I+ +YA CG I+ A R F+ +  KD VS++++IS  V NG A EAL +F+ M+ +  +PD  T+V +L A + L+AL  G   H +    GF  + S  N L+DMY+ CG +    +VF    ++ ++ W  MI  YG+HG G AA+  F  M    + PD +TF+ LL ACSHSGL+ EGK     M   + + P  EHY C+VDLLGRA  L EA+ F++ M  E    VW A L ACR+H+N +LGE  ++K+     +  G+ VL+SN+++A GRW D   VR++ KG GLKK+PGCSW+E+   +H F+  D+SHP+S +I++KL ++   + K  GY  +   VL +V +EEK ++L  HSE+LAIAY ++S   G PI +TKNLRVC DCH   K+++   +RE+IVRD +RFHHF+DG+C+C DFW
Sbjct:   77 FVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGLQDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRK-VQTKGMDVDTMMIGSTLLACSGLRCLSHAKEVHGYTLKRGLS-DLMMQNMIIDVYADCGNINYATRMFESIKCKDVVSWTSMISCYVHNGLANEALGVFYLMKETSVEPDSITLVSILSAAASLSALNKGKEIHGFIFRKGFMLEGSTVNSLVDMYACCGSLENAYKVFICTRSKSLVLWTTMINAYGMHGRGKAAVELFSIMEDQKLIPDHITFLALLYACSHSGLINEGKRLLETMKCKYQLEPWPEHYACLVDLLGRANHLEEAYHFVKSMQIEPTAEVWCAFLGACRIHSNKKLGEIAAQKLLDLDPDSPGSYVLISNVFAASGRWKDVEEVRMRMKGGGLKKNPGCSWIEVGNKVHTFLVRDKSHPESYKIYQKLAQITEKLEKEGGYVPQTKLVLHNVGKEEKVQMLYGHSERLAIAYGLMSTSEGTPIRITKNLRVCVDCHTFCKLVSKFFERELIVRDASRFHHFEDGVCSCGDFW 818          

Query:  382 SVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYK-DVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK--HWF----NAMSEDFNITPRMEHYIC 1830
            ++  WN ++ A   NG   RA+ L+ ++   GV    +T+P VLKAC  ++ +  G EIH      G  S V+V  +L+ +YAKC  +  A+ +F  M  + DVV+WN++I+ +SL+G   + + +  +MQKAG   N  T+VA L     ++    G  +H   L+ +   +V +   L+ M+ +   ++YA RIFD +D K+ + W++MI  +       EA+  F  +     + P  V+L SIL A  +L  L  G+ +H YA+K+  D N  +GNT++ MY+KC  +  A   FDKM +KD +S++ +I+   QN    EAL +   +Q  G D D   +   L ACS L  L H    H Y++  G  +D  + N++ID+Y+ CG IN   ++F+ +  +D++SW +MI  Y  +GL   A+  F+ M    ++PD +T + +LSA +    + +GK  H F      M E   +   ++ Y C
Sbjct:    5 TIFTWNAMMGANVSNGEPLRALELFREMRVLGVPFDSFTFPCVLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGL-QDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRKVQTKGMDVDTMMIGSTLLACSGLRCLSHAKEVHGYTLKRGL-SDLMMQNMIIDVYADCGNINYATRMFESIKCKDVVSWTSMISCYVHNGLANEALGVFYLMKETSVEPDSITLVSILSAAASLSALNKGKEIHGFIFRKGFMLEGSTVNSLVDMYAC 492          

Query:  682 KDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNE-VCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNI 1959
            + +  WNAM+     +G     +++  +M+  G   ++ T   VL        + +G  +HG  ++      V +   L+ MY+KC  I  AR++FD ++ +N+ V W+++I AY +     EA+ LF EM  +  +     TL + L+AC   +    G  +H   +KS   L+  V N +++M+ + G +  A R FD+++ KD ++++++I+G  QNG   EAL  F  +Q +   PD  +++ +L A   L  L +G   HAY++ +   ++  I N LIDMYSKC  +     VFD+M+ +D+ISW  +I  Y  +     A+     +   G+  D +     L ACS    ++  K       +       M++ I  +D+    G +  A    + +  + DV  W++++ +C VHN +
Sbjct:    4 RTIFTWNAMMGANVSNGEPLRALELFREMRVLGVPFDSFTFPCVLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREM-QKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGLQDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRKVQTKGMDVDTMMIGSTLLACSGLRCLSHAKEVHGYTLKRGLSDLMMQNMI--IDVYADCGNINYATRMFESIKCK-DVVSWTSMI-SCYVHNGL 425          

Query: 1282 MNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTR-DIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPF---------EADVRVWSALLA 1935
            M+ +   +++A++   V NG    AL +F  M++ G   D  T   VL AC  +  +  GA  H   I  G+ +   + N L+ MY+KC  I   R++FDRM  R D++SWN++I  Y ++G  M A+  F  M  AG+  +  T +  L AC  S     G     A+ +   +   ++ Y+        A  L   HV   KM +         E D   W++++A
Sbjct:    1 MHDRTIFTWNAMMGANVSNGEPLRALELFREMRVLGVPFDSFTFPCVLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQV---LDVYV--------ANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIA 217          

Query:  190 YHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQP-SVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALG-LASDVYVCTALIDLYAKCGG-LAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQC---IAYARRIFDAIDVKNEVCWSAMIGAYVI---CDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y +   +CIRS +      +H  L ++   L   S +L  +  LY  C     A  +F+ +     ++ W+ LI  YA N     AI  ++D+L+ G  P +Y +  V +ACS  + +  G+ I       G   SDV V  ALID++ K  G L  A  VF  M  ++VV W  MI  F   G   D + + + M  +G  P+  T+  V+   A+   LS G+  H   ++  L  +V +G  L+DMY+KC     +  AR++FD + V N + W+A+I  YV    CD  REA+ LF EMV + ++ P   T  S+L+AC  L+D+  G +V+   +K        VGN+++SMY++CG +++A + FD +  K+ VSY+ I++   ++  ++EA  +F+ ++ +G   +  T   +L   S + A+  G   H+  +  GF ++  ICN LI MYS+CG I    QVF+ M   ++ISW +MI G+  HG    A+  FH ML AG+ P++VT+I +LSACSH GL++EG   F +M  +  I PRMEHY C+VDLLGR+G L EA   +  MPF+AD  V    L ACRVH N++LG+  ++ I  +        +LLSN++++ G+W++ A +R K K + L K  GCSW+E+   +H F  GD SHPQ+ +I+++L++L + +K LGY     FVL DVEEE+KE+ L  HSEK+A+AY  +S    +PI V KNLRVCGDCH A K  +++ ++EI++RD  RFHHFKDG C+C D+W
Sbjct:  151 YSLLLKSCIRSHNYQLGHLVHHRLTQSGLELD--SVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCD--REAIELFLEMV-QGQVKPNHFTFSSVLKACANLSDIWLGEQVYALVVKMRLASINCVGNSLISMYSRCGNMENARKAFDVLFEKNLVSYNTIVNAYAKSLNSEEAFELFNEIEGAGTGVNAFTFASLLSGASSIGAIGKGEQIHSRILKSGFKSNLHICNALISMYSRCGNIEAAFQVFNEMGDGNVISWTSMITGFAKHGFATRALETFHKMLEAGVSPNEVTYIAVLSACSHVGLISEGLKHFKSMKVEHGIVPRMEHYACVVDLLGRSGHLEEAMELVNSMPFKADALVLRTFLGACRVHGNMDLGKHAAEIILEQDPHDPAAYILLSNLHASAGQWEEVAEIRKKMKERNLTKEAGCSWIEVENKVHKFYVGDTSHPQAQEIYDELDQLALKIKELGYIPSTDFVLHDVEEEQKEQYLFQHSEKIAVAYGFISTSTSRPIRVFKNLRVCGDCHTAFKYFSIVRRKEIVLRDANRFHHFKDGTCSCNDYW 931          

Query:  436 ERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYK-DVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRS-LSGEVVLGTGLLDMYSKCQ-CIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKC---GIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYA-KEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            ++AI     +   G  P   TY  +LK+C      + G  +H      GL  D  +  +LI LY+KCG   +A  +F  M  K D+V+W+A+I+ ++ +    + I     M + G  PN      V    +    +S GK + GF L+      +V +G  L+DM+ K    +  A ++FD +  +N V W+ MI  +      R+A+ LF +MVL   + P   TL  ++ AC ++  LS GR+ HC  +KSG DL+  VG +++ MYAKC   G +DDA + FD+M   + +S++AII+G VQ+G   +EA+ +F  M      P+  T   VL AC++L+ +  G   +A  +     +   + N LI MYS+CG +   R+ FD +  ++++S+N ++  Y        A   F+ +  AG   +  TF  LLS  S  G + +G+   + + +       +     ++ +  R G +  A     +M  + +V  W++++     H
Sbjct:  130 KKAISTLDQMSLQGTHPDLITYSLLLKSCIRSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYV-PDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDIWLGEQVYALVVKMRLASINCVGNSLISMYSRCGNMENARKAFDVLFEKNLVSYNTIVNAYAKSLNSEEAFELFNEIEGAGTGVNAFTFASLLSGASSIGAIGKGEQIHSRILKS-GFKSNLHICNALISMYSRCGNIEAAFQVFNEMG-DGNVISWTSMITGFAKH 638          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            C    +L   K++H   +K    L    F+   +  LY  C +++LA R+F  +P  + + WN L+  YA  G  ++ + L+  + +   K +K+T   VLK C+   +L  G+ +H  A   G   D ++  +L+D+Y+KCG + +A  VF  +   DVVAW+AMI G    G   +  ++   M++ G  PN  T+ +++ T      L  G+++HG   +     + ++   L+ MY K +C+    ++F+A+   + V W+A++  +    +      +F +M+L +   P   T  S+LR+C+ L D   G++VH + IK+  D +  VG  ++ MYAK   ++DA   FD++ ++D  S++ IISG  Q   A++A+  F  MQ  G  P+  T+   L  CSH+A L++G   HA ++  G   D  + + L+D+Y KCG +     +F  +++RDI+SWN +I GY  HG G  A+  F  ML+ GI PD+ TFIG+LSACS  GLV EGK  F++MS+ + I P +EHY CMVD+LGRAG   E  +FI++M       +W  +L AC++H N++ GE+ +KK+         + +LLSNI+++ GRWDD   +R     +G+KK PGCSWVE++G +H F+  D SHP+  +I+ KL++L   +  +GY  +   VL +V  +EK   L YHSE+LA+++A+LS    KPI + KNLR+C DCH  +K+I+ IT +EI+VRD+ RFHHFK G C+C D W
Sbjct:  106 CSMCLNLEFGKQVHVEAIKAGLLLD--LFVGTALVDLYARCGEMELAERLFFGMPDKNGVSWNALLNGYAQLGDGKKVLKLFCKMKECETKFSKFTLSTVLKGCANTGSLREGKVLHALALRSGCEIDEFLGCSLVDMYSKCGTVYDALKVFTKIRNPDVVAWSAMITGLDQQGHGQEAAELFHLMRRKGARPNQFTLSSLVSTATNMGDLRYGQSIHGCICKYGFESDNLVSNPLIMMYMKSRCVEDGNKVFEAMTNPDLVSWNALLSGFYDSQTCGRGPRIFYQMLL-EGFKPNMFTFISVLRSCSSLLDPEFGKQVHAHIIKNSSDDDDFVGTALVDMYAKARCLEDAGVAFDRLVNRDIFSWTVIISGYAQTDQAEKAVKYFRQMQREGIKPNEYTLASCLSGCSHMATLENGRQLHAVAVKAGHFGDIFVGSALVDLYGKCGCMEHAEAIFKGLISRDIVSWNTIISGYSQHGQGEKALEAFRMMLSEGIMPDEATFIGVLSACSFMGLVEEGKKRFDSMSKIYGINPSIEHYACMVDILGRAGKFNEVKIFIEEMNLTPYSLIWETVLGACKLHGNVDFGEKAAKKLFEMEPMMDSSYILLSNIFASKGRWDDVRNIRALMTSRGIKKEPGCSWVEVDGQVHVFLSQDGSHPKIREIYAKLDKLGQSLMSIGYVPKTEVVLHNVSNKEKMEHLYYHSERLALSFALLSTNAVKPIRIFKNLRICEDCHDFMKLISDITNQEIVVRDIRRFHHFKRGTCSCQDRW 872          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGL 2004
            C     + + K IH +L+ +   L   S L   + + Y  C     A +V  E+PQ  V+ W  LI  +   G    ++ LY ++ +  V+  ++     LKACS    LE G+++H  A   GL  D++V TAL+DLYA+CG +  A+ +F GM  K+ V+WNA++ G++  G     +++  +M++  T  +  T+  VL   A   +L +GK +H  +LR     +  LG  L+DMYSKC  +  A ++F  I   + V WSAMI         +EA  LF  ++ RK   P   TL S++   T + DL  G+ +H    K GF+ + +V N ++ MY K   ++D  + F+ M + D VS++A++SG   +        IF+ M L GF P++ T + VL +CS L   + G   HA+ I +    D  +   L+DMY+K   +      FDR+V RDI SW  +I GY        A+  F  M   GIKP++ T    LS CSH   +  G+   +A++        +     +VDL G+ G +  A    + +    D+  W+ +++    H   E   E  + +  +G+
Sbjct:    5 CASKGDVKEGKAIHGNLITSGVELD--SHLWVSLINFYAKCRSRFFARKVLAEMPQRDVVSWTALISGFVNEGCGSESVSLYCEMRKENVRANEFALATALKACSMCLNLEFGKQVHVEAIKAGLLLDLFVGTALVDLYARCGEMELAERLFFGMPDKNGVSWNALLNGYAQLGDGKKVLKLFCKMKECETKFSKFTLSTVLKGCANTGSLREGKVLHALALRSGCEIDEFLGCSLVDMYSKCGTVYDALKVFTKIRNPDVVAWSAMITGLDQQGHGQEAAELF-HLMRRKGARPNQFTLSSLVSTATNMGDLRYGQSIHGCICKYGFESDNLVSNPLIMMYMKSRCVEDGNKVFEAMTNPDLVSWNALLSGFYDSQTCGRGPRIFYQMLLEGFKPNMFTFISVLRSCSSLLDPEFGKQVHAHIIKNSSDDDDFVGTALVDMYAKARCLEDAGVAFDRLVNRDIFSWTVIISGYAQTDQAEKAVKYFRQMQREGIKPNEYTLASCLSGCSHMATLENGRQ-LHAVAVKAGHFGDIFVGSALVDLYGKCGCMEHAEAIFKGL-ISRDIVSWNTIISGYSQHGQGEKALEAFRMMLSEGI 597          

Query:  508 VLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK----HWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLE 2007
            +L+ C+    ++ G+ IH +    G+  D ++  +LI+ YAKC     A+ V   M  +DVV+W A+I+GF   G   +++ +  +M+K     N   +   L   +    L  GK +H  +++  L  ++ +GT L+D+Y++C  +  A R+F  +  KN V W+A++  Y      ++ + LF +M    E   +  TL ++L+ C     L  G+ +H  A++SG +++  +G +++ MY+KCG + DA++ F K+ + D V++SA+I+G  Q G+ +EA  +FH M+  G  P+  T+  ++   +++  L++G   H     +GF +D  + N LI MY K   +  G +VF+ M   D++SWNA++ G+            F+ ML  G KP+  TFI +L +CS       GK    H     S+D +          +VD+  +A  L +A V   ++    D+  W+ +++     +  E   +  +++Q +G++
Sbjct:    1 MLRECASKGDVKEGKAIHGNLITSGVELDSHLWVSLINFYAKCRSRFFARKVLAEMPQRDVVSWTALISGFVNEGCGSESVSLYCEMRKENVRANEFALATALKACSMCLNLEFGKQVHVEAIKAGLLLDLFVGTALVDLYARCGEMELAERLFFGMPDKNGVSWNALLNGYAQLGDGKKVLKLFCKM-KECETKFSKFTLSTVLKGCANTGSLREGKVLHALALRSGCEIDEFLGCSLVDMYSKCGTVYDALKVFTKIRNPDVVAWSAMITGLDQQGHGQEAAELFHLMRRKGARPNQFTLSSLVSTATNMGDLRYGQSIHGCICKYGFESDNLVSNPLIMMYMKSRCVEDGNKVFEAMTNPDLVSWNALLSGFYDSQTCGRGPRIFYQMLLEGFKPNMFTFISVLRSCSSLLDPEFGKQVHAHIIKNSSDDDDFVG-----TALVDMYAKARCLEDAGVAFDRL-VNRDIFSWTVIISGYAQTDQAEKAVKYFRQMQREGIK 497          

Query: 1117 ILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYI--CMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAY 2076
            +LR C    D+  G+ +H   I SG +L++ +  ++++ YAKC     A +   +M  +D VS++A+ISG V  G   E++ ++  M+      +   +   L ACS    L+ G   H  +I  G   D  +   L+D+Y++CG++    ++F  M  ++ +SWNA++ GY   G G   +  F  M     K    T   +L  C+++G + EGK   +A++        ++ ++   +VD+  + G + +A     K+    DV  WSA++       + +   E+   ++ KG     N   LS++ S      D  Y
Sbjct:    1 MLRECASKGDVKEGKAIHGNLITSGVELDSHLWVSLINFYAKCRSRFFARKVLAEMPQRDVVSWTALISGFVNEGCGSESVSLYCEMRKENVRANEFALATALKACSMCLNLEFGKQVHVEAIKAGLLLDLFVGTALVDLYARCGEMELAERLFFGMPDKNGVSWNALLNGYAQLGDGKKVLKLFCKMKECETKFSKFTLSTVLKGCANTGSLREGK-VLHALA--LRSGCEIDEFLGCSLVDMYSKCGTVYDALKVFTKIR-NPDVVAWSAMITGLDQQGHGQEAAELFHLMRRKG--ARPNQFTLSSLVSTATNMGDLRY 316          

Query:  163 YNIYVYQCHYHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +N Y+Y         +CIR+      K +H  ++K    L    F    + + Y+  + +  A+++FDE+P  + + +  LI+ Y+    F  AI L+  L   G +   + +  VLK     +  + G  +H     LG  SD +V TALID Y+ CG    A+ VF  + YKD+V+W  M+A +  +  +++++++  +M+  G  PN  T  +VL         + GKA+HG + + S   E+ +G  L+D+Y K   +  A ++F+ +   + + WS MI  Y   +   EA+ +F  M  R  + P   TL S+L+AC  L DL  G ++HC+ +K G D+N  V N ++ MYAKCG ++++++ F +  +   VS++ +I G VQ G  ++AL++F  M          T   VL AC+ +AAL+ G+  H+ S+   +  +T + N LIDMY+KCG I   R VFD +   D +SWNAMI GY +HGL   A+  F  ML    KPD VTF+G+LSACS++GL+  G+ +F +M E+++I P  EHY CMV LLGR+G L +A   + ++PFE  V VW ALL+AC +HN++ELG   ++++     E     VLLSNIY+   RW + A +R   K +G++K PG SW+E  G +H F  GD SHP +  I+  LE L +  +  GY  + S VL DVE+ +KE+ L  HSE+LA+AY ++      P+ + KNLR+C DCHAAIK+I+ I +R+II+RD+ RFHHF +GIC+C D+W
Sbjct:   42 FNTYIYGSLLQ----SCIRNGDCATGKYLHCEIIKKGNCLD--LFANNILLNFYVKYDSLPDAAKLFDEMPDRNTVSFVTLIQGYSQCLRFSEAIGLFSRLQGEGHELNPFVFSTVLKLLVSAEWAKLGFSVHACVYKLGFDSDAFVGTALIDCYSVCGYAECARQVFDAIEYKDMVSWTGMVACYVENECFEESLKLFSRMRIVGFKPNNFTFASVLKACVGLEVFNVGKAVHGCAFKTSYLEELFVGVELIDLYIKSGDVDDALQVFEEMPKDDVIPWSFMIARYAQSEQSEEAIEMFCRM-RRGLVLPNQFTLASLLQACASLVDLQLGNQIHCHVVKVGLDMNVFVSNALMDMYAKCGRMENSLQLFSESPNCTDVSWNTVIVGYVQAGNGEKALILFKDMLECQVQGTEVTYSSVLRACAGIAALEPGSQIHSLSVKTIYDKNTVVGNALIDMYAKCGNIKDARLVFDMLREHDQVSWNAMISGYSVHGLYGEALKTFESMLETECKPDKVTFVGILSACSNAGLLDRGQAYFKSMVEEYDIEPCAEHYTCMVWLLGRSGHLDKAAKLVHEIPFEPSVMVWRALLSACVIHNDVELGRISAQRVLEIEPEDEATHVLLSNIYANARRWGNVASIRTSMKRKGIRKEPGLSWIENQGRVHYFSVGDTSHPDTKLINGMLEWLNMKARNEGYVPDFSSVLLDVEDVDKEQRLWVHSERLALAYGLIRTPSISPLRIIKNLRICADCHAAIKLISKIVQRDIIIRDMNRFHHFHEGICSCGDYW 820          

Query:  241 KKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQ---ALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRS-LSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSG----------------FDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAG-----IKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEAD-VRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            K+IH H+ K       +  +   + ++Y  C  +  A +VFD I +   + WN +I A      +E AI  +  +L  G +P+ +T   +  ACS L+    L  G++IH      G     +   AL+ +YAK G L +A+++      +D+V WN+MI+ FS +  + + +  L  M   G  P+  T  +VLP  +  + L  GK +H ++LR   +     +G+ L+DMY  C  +   R +FD +  +    W+AMI  Y   +   +A+ LF EM     +     T+ SI+ A  +   +SR   +H Y IK G + N  + N ++ MY++ G I  + R FD M  +D VS++ II+  V  G + +ALL+ H MQ                   F P+  T++ VLP C+ L+AL  G   HAY+I +   +  ++ + L+DMY+KCG +N  R+VFD+M  R++I+WN +I+ YG+HG G  ++  F  M+A G     +KP +VTFI L ++CSHSG+V EG   F+ M  +  I P  +HY C+VDL+GRAG + EA+  +  MP   D V  WS+LL ACR+++NIE+GE  ++ +     +   + VLLSNIYS+ G WD A  +R + K  G+KK PGCSW+E    +H F+ GD SHPQS ++H+ LE L   +K+ GY  + + VL D++EEEKE IL  HSEKLAIA+ IL+  PG  I V KNLRVC DCH A K I+ I  REII+RD  RFHHFKDG C+C D+W
Sbjct:  110 KQIHAHVFKFGYGSFSSVTIDNTLVNMYGKCGGLGDAYKVFDRITERDQVSWNSIISALCRFEEWEVAIKAFRLMLMEGFEPSSFTLVSMALACSNLRKRDGLWLGKQIHGCCFRKGHWR-TFSNNALMAMYAKLGRLDDAKSLLVLFEDRDLVTWNSMISSFSQNERFMEALMFLRLMVLEGVKPDGVTFASVLPACSHLDLLRTGKEIHAYALRTDDVIENSFVGSALVDMYCNCGQVESGRLVFDGVLDRKIGLWNAMIAGYAQSEHDEKALMLFIEMEAAAGLYSNATTMSSIVPAYVRCEGISRKEGIHGYVIKRGLETNRYLQNALIDMYSRMGDIKTSKRIFDSMEDRDIVSWNTIITSYVICGRSSDALLLLHEMQRIEEKSTYDGDYNDEKQVPFKPNSITLMTVLPGCASLSALAKGKEIHAYAIRNLLASQVTVGSALVDMYAKCGCLNLARRVFDQMPIRNVITWNVIIMAYGMHGKGKESLELFEDMVAEGAKGGEVKPTEVTFIALFASCSHSGMVDEGLSLFHKMKNEHGIEPAPDHYACIVDLVGRAGKVEEAYGLVNTMPSGFDKVGAWSSLLGACRIYHNIEIGEIAAENLLQLQPDVASHYVLLSNIYSSAGLWDKAMNLRRRMKAMGVKKEPGCSWIEYGDEVHKFLAGDLSHPQSEKLHDFLETLSERLKKEGYVPDTACVLHDIDEEEKETILCGHSEKLAIAFGILNTPPGTTIRVAKNLRVCNDCHTASKFISKIEDREIILRDARRFHHFKDGTCSCGDYW 894          

Query:  394 WNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLA--SDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAV---LPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDL-NTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQ-LSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHM----------------LAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEG 2010
            W   +R+ + +  F  AI  Y +++ SGV P  + +P VLKA +G+Q L  G++IH H    G    S V +   L+++Y KCGGL +A  VF  +  +D V+WN++I+       ++  I+    M   G  P++ T+V++      + + + L  GK +HG   R+           L+ MY+K   +  A+ +    + ++ V W++MI ++   +   EA+     MVL + + P  VT  S+L AC+ L  L  G+ +H YA+++   + N+ VG+ ++ MY  CG ++     FD +  +    ++A+I+G  Q+ + ++AL++F  M+  +G   +  TM  ++PA      +      H Y I  G  T+  + N LIDMYS+ G I   +++FD M  RDI+SWN +I  Y I G    A+   H M                     KP+ +T + +L  C+    + +GK   +A +    +  ++     +VD+  + G L  A     +MP   +V  W+ ++ A  +H   +   E+ + +  +G +G
Sbjct:   58 WIESLRSRSRSNLFREAISTYIEMIGSGVSPDNFAFPAVLKAVAGIQELYLGKQIHAHVFKFGYGSFSSVTIDNTLVNMYGKCGGLGDAYKVFDRITERDQVSWNSIISALCRFEEWEVAIKAFRLMLMEGFEPSSFTLVSMALACSNLRKRDGLWLGKQIHGCCFRKG-HWRTFSNNALMAMYAKLGRLDDAKSLLVLFEDRDLVTWNSMISSFSQNERFMEALMFLRLMVL-EGVKPDGVTFASVLPACSHLDLLRTGKEIHAYALRTDDVIENSFVGSALVDMYCNCGQVESGRLVFDGVLDRKIGLWNAMIAGYAQSEHDEKALMLFIEMEAAAGLYSNATTMSSIVPAYVRCEGISRKEGIHGYVIKRGLETNRYLQNALIDMYSRMGDIKTSKRIFDSMEDRDIVSWNTIITSYVICGRSSDALLLLHEMQRIEEKSTYDGDYNDEKQVPFKPNSITLMTVLPGCASLSALAKGKE-IHAYAIRNLLASQVTVGSALVDMYAKCGCLNLARRVFDQMPIR-NVITWNVIIMAYGMHGKGKESLELFEDMVAEGAKG 615          

Query:  694 AWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHG--FSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKL---TDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTS-ICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHM-LAAGIKPDDVTFIGLLSACSHSGLVT--EGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAA 1938
            +W   +   S   L+ + I   ++M  +G SP+     AVL  VA    L  GK +H   F         V +   L++MY KC  +  A ++FD I  +++V W+++I A    +    A+  F  ++L +   P+  TL S+  AC+ L     L  G+++H    + G    T   N +++MYAK G +DDA         +D V+++++IS   QN    EAL+    M L G  PD  T   VLPACSHL  L+ G   HAY++      + S + + L+DMY  CG++  GR VFD ++ R I  WNAMI GY        A+  F  M  AAG+  +  T   ++ A      ++  EG H +  +         +++   ++D+  R G +  +      M  + D+  W+ ++ +
Sbjct:   57 SWIESLRSRSRSNLFREAISTYIEMIGSGVSPDNFAFPAVLKAVAGIQELYLGKQIHAHVFKFGYGSFSSVTIDNTLVNMYGKCGGLGDAYKVFDRITERDQVSWNSIISALCRFEEWEVAIKAF-RLMLMEGFEPSSFTLVSMALACSNLRKRDGLWLGKQIHGCCFRKG-HWRTFSNNALMAMYAKLGRLDDAKSLLVLFEDRDLVTWNSMISSFSQNERFMEALMFLRLMVLEGVKPDGVTFASVLPACSHLDLLRTGKEIHAYALRTDDVIENSFVGSALVDMYCNCGQVESGRLVFDGVLDRKIGLWNAMIAGYAQSEHDEKALMLFIEMEAAAGLYSNATTMSSIVPAYVRCEGISRKEGIHGY-VIKRGLETNRYLQN--ALIDMYSRMGDIKTSKRIFDSME-DRDIVSWNTIITS 474          

Query:  988 NEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDL--NTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQ--------HGAC---GHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK--HWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDA--------AYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDM-KRLGYCAENSFVLQDVEEEE 2292
            ++  W   + +    +  REA++ + EM+    ++P      ++L+A   + +L  G+++H +  K G+    +  + NT+++MY KCG + DA + FD++  +D VS+++IIS   +    + A+  F  M + GF+P   T+V +  ACS+L            HG C   GH  +  +         N L+ MY+K G+++  + +      RD+++WN+MI  +  +   M A+     M+  G+KPD VTF  +L ACSH  L+  GK  H +   ++D  +         +VD+    G +    +    +  +  + +W+A++A      + E                   L+L   + +A G + +A        AYVR     +G+ +  G         IHG+V       +  + +  L+  L+DM  R+G    +  +   +E+ +
Sbjct:   54 SQASWIESLRSRSRSNLFREAISTYIEMI-GSGVSPDNFAFPAVLKAVAGIQELYLGKQIHAHVFKFGYGSFSSVTIDNTLVNMYGKCGGLGDAYKVFDRITERDQVSWNSIISALCRFEEWEVAIKAFRLMLMEGFEPSSFTLVSMALACSNLRKRDGLWLGKQIHGCCFRKGHWRTFSN---------NALMAMYAKLGRLDDAKSLLVLFEDRDLVTWNSMISSFSQNERFMEALMFLRLMVLEGVKPDGVTFASVLPACSHLDLLRTGKEIHAYALRTDD--VIENSFVGSALVDMYCNCGQVESGRLVFDGV-LDRKIGLWNAMIAGYAQSEHDEKA-----------------LMLFIEMEAAAGLYSNATTMSSIVPAYVRC----EGISRKEG---------IHGYV-----IKRGLETNRYLQNALIDMYSRMGDIKTSKRIFDSMEDRD 464          

Query:  322 YITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML-YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y    ++  A ++F E P  S I W  L+  Y   G    A  L+ ++   G +P++YT   VL  CS    L+ G +IH +A       +V+V T+L+D+Y KC  + EA+ +F  +   K    W+AM+AG+S +G     I+    M+  G   N  T  ++L       A   G  +HG  +R      + + + L+DMY+KC+ +  A+R+   ++  +EV W+++I   V      +A++ F +M  R ++     TL S+L +   +  +     VHC  IK+GF+   +V N ++ MYAK G +D A+  F KM  KD VS++++++G   NG  +EA+ +F  M++SG  PD   +  VL AC+ L  +  G   HA  +  G  +  S+ N L+ MY+KCG I    + FD M TRD+ISW A+IVGY  +G G  ++  +  M+A G KPD +TFIGLL ACSH+GL+  G+ +F AM + + I P  EHY CM+DLLGR+G LAEA   + +M    D  VW ALLAACRVH  +ELGE  +K +       +   V+LSN+YSA G+W+DAA +R   + +G+ K PG SW+E N  +  F+  D++HP   +I+ K++E+++ +K  GY  + SF L D ++E KE  L YHSEKLA+A+ +L++  G PI + KNLRVCGDCH A+K  + +  R II+RD   FHHF +G C+C D+W
Sbjct:    5 YANSGRLTEAKKLFYETPMKSSITWTSLLSGYCRYGFENEAFELFLEMQLEGQRPSQYTLGSVLGLCSTNGLLQKGEQIHGYAIKTWFDWNVFVVTSLVDMYGKCKCVFEAECLFEMVADCKYNAVWSAMLAGYSHYGYGYKAIECFRNMRNEGVESNQFTFPSILRACGAVMACDFGSQVHGCIVRTGFGANIFVQSALVDMYAKCRDLNSAKRVLGNMEFDDEVSWNSLILGCVREGFEEDALSFFQKMRSR-DMKIDEYTLPSVLNSFASMKVMQNAISVHCLIIKTGFEAYKLVNNALIDMYAKQGKLDCAIMVFSKMVDKDVVSWTSLVTGYSHNGSYEEAIKLFCKMRISGVYPDQIAVASVLSACAELTVMDFGQQIHATLVKSGLESSLSVDNSLVTMYAKCGSIVDANRAFDNMPTRDVISWTALIVGYAQNGRGKHSLQFYDQMIATGTKPDYITFIGLLFACSHNGLLGSGRAYFEAMDKVYGIKPGPEHYACMIDLLGRSGKLAEAKGLLNQMVVAPDAVVWKALLAACRVHKELELGEMAAKNLFELEPMNSMPYVMLSNMYSAAGKWEDAARIRRLMRSRGICKEPGYSWIETNSKVSTFMSEDRNHPLRNEIYSKIDEIIMLIKEAGYVPDMSFALHDTDDEVKELGLAYHSEKLAVAFGLLTVPQGAPIRIFKNLRVCGDCHTAMKYTSKVYARHIILRDSNCFHHFTEGRCSCGDYW 737          

Query:  295 FLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRV-----HCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKM-NSKDTVSYSAIISGC 1329
            F+   +  +Y  C  ++ A RV   +     + WN LI      G  E A+  +  +    +K  +YT P VL + + ++ ++    +H      G  +   V  ALID+YAK G L  A  VF  M+ KDVV+W +++ G+S +G Y++ I++  +M+ +G  P+   + +VL   A+   +  G+ +H   ++  L   + +   L+ MY+KC  I  A R FD +  ++ + W+A+I  Y      + ++  +D+M+      P  +T   +L AC+    L  GR         Y IK G +        ++ +  + G + +A    ++M  + D V + A+++ C
Sbjct:  199 FVQSALVDMYAKCRDLNSAKRVLGNMEFDDEVSWNSLILGCVREGFEEDALSFFQKMRSRDMKIDEYTLPSVLNSFASMKVMQNAISVHCLIIKTGFEAYKLVNNALIDMYAKQGKLDCAIMVFSKMVDKDVVSWTSLVTGYSHNGSYEEAIKLFCKMRISGVYPDQIAVASVLSACAELTVMDFGQQIHATLVKSGLESSLSVDNSLVTMYAKCGSIVDANRAFDNMPTRDVISWTALIVGYAQNGRGKHSLQFYDQMI-ATGTKPDYITFIGLLFACSHNGLLGSGRAYFEAMDKVYGIKPGPEHYA----CMIDLLGRSGKLAEAKGLLNQMVVAPDAVVWKALLAAC 544          

Query:  223 KSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEV-----CWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDL---NTMVGNTILSMYAKCGIIDDAVRFFDKMNSK 1293
            K +  A  +H  ++K  T  +    +   +  +Y    ++D A  VF ++    V+ W  L+  Y+ NG +E AI L+  +  SGV P +     VL AC+ L  ++ G++IH      GL S + V  +L+ +YAKCG + +A   F  M  +DV++W A+I G++ +G    ++Q   QM   GT P+  T + +L   +    L  G+A                                    F+A+D    +      ++ MI        + EA  L ++MV    + P  V   ++L AC    +L  G      A K+ F+L   N+M    + +MY+  G  +DA R    M S+
Sbjct:  278 KVMQNAISVHCLIIK--TGFEAYKLVNNALIDMYAKQGKLDCAIMVFSKMVDKDVVSWTSLVTGYSHNGSYEEAIKLFCKMRISGVYPDQIAVASVLSACAELTVMDFGQQIHATLVKSGLESSLSVDNSLVTMYAKCGSIVDANRAFDNMPTRDVISWTALIVGYAQNGRGKHSLQFYDQMIATGTKPDYITFIGLLFACSHNGLLGSGRA-----------------------------------YFEAMDKVYGIKPGPEHYACMIDLLGRSGKLAEAKGLLNQMV----VAPDAVVWKALLAACRVHKELELGE----MAAKNLFELEPMNSMPYVMLSNMYSAAGKWEDAARIRRLMRSR 597          

Query:  148 NDFSAYNIYVYQCHYHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREI 2454
            ++FS   +      Y      CIRSKSLPQ KKIHQ LLKNTT LKD+SFLLEKVAHLYITCNQ+ LA RVFD+IPQPSVILWNLLIR YAWNGPFE+AI LYY +L+SGV+PT YTYPFVLKACSGLQALE GREIH+HA+ LGL SDVYVCTALIDLYAKCG L EAQ+VF GMLYKD+VAWNAMI GFSLHGLYDDT+Q+LVQMQ+AGTSPN+STIV+VLPTVAQANAL QGKAMHG+SLRR  SGEVVLGTGLLDMYSK QCIAYARRIFDA++ KNEVCWSAMIGAYVICDSM EA+ LF EMV+R+EINPT VTLGSILRAC KLTDLSRGRRVHCYAIK+GFDL+ MVGNT+LS+YAKCGIIDDAVRFFD MNSKDTVSY AIISG VQNGYAKEALL+FH+MQLSG +PD+ATM GVLPACSHLAALQHGACGHAYSIVHGF TDTSICN LIDMYSKCGKIN GR+VFD+MVTRDIISWNAMIVGYG HGLGM AISQFHHM ++GIKPDDVTFIGLLSACSHSGLVTEGKHWF+ MS++FNI PRMEHYICMVD+L RAG L EAH FIQ+MPFEADVRVWSALLAACRVHNN+ELGEEVSKKIQGKGLEGTGNLVLLSN+YSAVGRWDDAA VRIKQK QGLKKSPGCSWVEI+G+IHGFVGGDQSHPQSAQIHEKLEELLVDMK+LGY  EN FVLQDVEEEEKERILLYHSEKLAIAYAIL L PGKPILVTKNLRVCGDCHAAIK ITL+TKREI
Sbjct:  167 HNFSTNTLTRLDFDYKHLLEACIRSKSLPQGKKIHQLLLKNTTHLKDSSFLLEKVAHLYITCNQLQLACRVFDKIPQPSVILWNLLIRGYAWNGPFEKAIDLYYGMLKSGVQPTNYTYPFVLKACSGLQALEVGREIHEHARGLGLHSDVYVCTALIDLYAKCGDLVEAQSVFHGMLYKDIVAWNAMIXGFSLHGLYDDTVQLLVQMQRAGTSPNSSTIVSVLPTVAQANALRQGKAMHGYSLRRGFSGEVVLGTGLLDMYSKSQCIAYARRIFDAMNFKNEVCWSAMIGAYVICDSMTEAITLFHEMVIREEINPTAVTLGSILRACAKLTDLSRGRRVHCYAIKAGFDLDKMVGNTMLSVYAKCGIIDDAVRFFDTMNSKDTVSYGAIISGYVQNGYAKEALLMFHNMQLSGINPDVATMKGVLPACSHLAALQHGACGHAYSIVHGFCTDTSICNALIDMYSKCGKINIGRKVFDKMVTRDIISWNAMIVGYGNHGLGMEAISQFHHMQSSGIKPDDVTFIGLLSACSHSGLVTEGKHWFSKMSQEFNINPRMEHYICMVDILARAGHLDEAHSFIQRMPFEADVRVWSALLAACRVHNNMELGEEVSKKIQGKGLEGTGNLVLLSNLYSAVGRWDDAADVRIKQKDQGLKKSPGCSWVEIDGVIHGFVGGDQSHPQSAQIHEKLEELLVDMKQLGYRVENRFVLQDVEEEEKERILLYHSEKLAIAYAILCLSPGKPILVTKNLRVCGDCHAAIKFITLVTKREI 935          

Query:  307 KVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYA--IKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            K+  L+      + A+RVFD +     + ++ L++ YA N     A   +  +   GVKP  Y + ++LK C     L  G+EIH    + G AS+++  TA+++LYAKC  + EA  +F  M  +D+V+WN ++AG++ +GL    ++++++MQ+ G  P+  T+V +LP VA   +L  GK++H + +R      V L T L+DMYSKC  +  AR IF  +  K  V W++MI  YV  +  +EAM +F +M L +   PT VT+   L AC  L DL RG  VH     +K G D++ M  N+++SMY+KC  +D A + F+K+  K  VS++A+I G  QNG   EAL  F  M      PD  TMV V+PA + L+  +     H   I   F  +  +   L+DMY+KCG ++  R++FD M  R + +WNAMI GYG +GLG +A+  F+ M    IKP+D+TF+ ++SACSHSGLV EG  +F +M ED+ + P M+HY  MVDLLGRAG L EA  FIQ MP E  + V+ A+L ACR+H NIELGE+ + KI        G  VLL+NIY     WD  A VR   + +GL+K+PGCS V++   +H F  G  SHPQS +I+  L+ L  ++K  GY  + + +  DVE + KE++L  HSEKLAIA+ +L+  PG  I + KNLRVCGDCH A K I+L+T+REIIVRD+ RFHHFK+G C+C D+W
Sbjct:   97 KLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKM-LDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVM--NSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHSARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGRLYEAWDFIQNMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFKLNPADGGYHVLLANIYQTASLWDKVANVRTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSKRIYSFLDTLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGATIHIRKNLRVCGDCHNATKYISLVTRREIIVRDMHRFHHFKNGTCSCGDYW 832          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSI--CNVLIDMYSKCGKINRGRQVFDRM-VTRDIISWNAMIVGYGIH 1641
            C  +  L + K+IH  L+  ++      F +  V +LY  C QVD A ++FD +P+  ++ WN ++  YA NG  + A+ L   + + G KP   T   +L A +   +L  G+ IH +    G  S V + TAL+D+Y+KCG +  A+ +F  M +K VV+WN+MI G+  +    + +++  +M   G  P   TI+  L   A    L +G  +H    +  L  +V +   L+ MYSKC+ +  A +IF+ +  K  V W+AMI  Y     + EA++ F EM   + I P   T+ S++ A  +L+   + + +H   I+  FD N  V   ++ MYAKCG +  A + FD M+ +   +++A+I G   NG  K A+ +F+ M+     P+  T + V+ ACSH   ++ G    A S+   +G + ++     ++D+  + G++         M +   I  + AM+    IH
Sbjct:  168 CGDNADLRRGKEIHGDLI--SSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEM-HSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHSARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGTIKPNDITFLCVISACSHSGLVEEGLQYFA-SMKEDYGLEPAMDHYGAMVDLLGRAGRLYEAWDFIQNMPMEPGITVFGAMLGACRIH 643          

Query:  490 KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKE---INPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALL 1932
            K+    +L+ C+  Q L    +I       GL ++    T L+ L+   G   EA  VF  +  K  V ++ ++ G++ +    D      +M+  G  P       +L        L +GK +HG  +    +  +   T ++++Y+KC+ +  A ++FD +  ++ V W+ ++  Y      + AM    E+V+R +     P P+TL ++L A      L  G+ +H Y +++GF+ +  +   ++ MY+KCG +  A   F +M  K  VS++++I G VQN   KEA+ +F  M   GF+P   T++  L AC+ L  L+ G   H        G+D S+ N LI MYSKC +++   ++F+++  +  +SWNAMI+GY  +G    A+S F  M +  IKPD  T + ++ A +   +  + K W + +         +     +VD+  + G +  A      M  E  V  W+A++
Sbjct:   60 KHPAAILLELCTSXQELN---QIIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAM----ELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAK-WIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHSARKLFDMMD-ERHVTTWNAMI 534          

Query: 1117 ILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWD 2064
            +L  CT   +L++   +    IK+G     +    ++S++   G  ++A R FD +  K  V Y  ++ G  +N    +A   F  M+  G  P +     +L  C   A L+ G   H   I  GF ++      ++++Y+KC +++   ++FDRM  RD++SWN ++ GY  +GL   A+     M   G KPD +T + LL A +  G +  GK   +A          +     +VD+  + G +  A +   +M  +  V  W++++     + + +   EV +K+  +G E T N+ ++  +++     D
Sbjct:   66 LLELCTSXQELNQ---IIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKS-IHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVS-WNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPT-NVTIMEALHACADLGD 375          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            C    SL   K +H  +  N         L  K+  +Y+ C  +  A RVFD++    V +WNL+I  YA    F   ++L+  + + G++   YT+  VLK  S L  +  G  IH +   LG  SD  V  +L+  Y K   +  A+ VF  +  +DV++WN+MI+ +  +GL +  +++  QM   G   + +TI+ VL        LS G+A+H ++++ S   +V+    +LDMYSKC  ++ A ++F  +  ++ V W++MI  ++      EA+ LF EM  R  +NP   T+ SIL AC     L +GR +H Y  + G D +  V NT++ MYAKCG ++DA   F +M +KD VS++ +I G  +N    EAL +F  M      PD  T+  VLPAC+ LAAL  G   H + + +G+ ++  + N L+DMY KCG +   R +FD +  +D+ISW  +  GYG+HG G  AI+ F+ M  AGI+PD V+FI +L ACSHSGL  E   +F+ M  D+ I P++EHY CMVDLL R G L +A+ FI+ MP E D  +W +LL  CR+H++++L E+V++ +     E TG  VLL+NIY+   +W++   +R +   +GLKK+PGCSW+EI G +  FV GD SHPQ+A+I   L+ L + MK  G   +  + L + +E EKE  L  HSEKLAIA+ IL+L+PGK I VTKNLRVCGDCH   K I+  ++REI++RD  RFHH KDG C+C  FW
Sbjct:  554 CAGMMSLQDGKXVHSVICDNGVEADGQ--LGAKLVFMYVKCGDLREARRVFDKLSNGKVFVWNLMINEYAKVRNFREGVYLFGKMQELGIQANSYTFSCVLKCFSALGCVREGEWIHGYLYKLGFGSDNTVGNSLMAFYFKNRRIEXARKVFDELCDRDVISWNSMISAYVSNGLAEKGVEIFRQMVSLGIDVDLATIINVLMACVAGGNLSLGRALHAYAIKASFDEDVMFCNNVLDMYSKCGDLSSAIQVFKKMGERSVVSWTSMIAGHIREGLSDEAIGLFSEME-RDGVNPDAYTITSILHACASSGSLKKGRDIHNYIKEHGMDSSLYVCNTLMDMYAKCGSMEDAHSVFSRMPAKDIVSWNTMIGGYSKNCLPNEALKLFSEMMQKS-KPDSMTIASVLPACASLAALNRGQEIHGHILRNGYFSERHVANALVDMYVKCGVLVLARLLFDXIPVKDLISWTVIXAGYGMHGFGREAIAAFNEMRKAGIEPDSVSFISILYACSHSGLXDEAWRFFDTMRNDYGIVPKLEHYACMVDLLSRTGNLTKAYKFIKTMPIEPDATIWGSLLCGCRIHHDVKLAEKVAEHVFELEPENTGYYVLLANIYAEAEKWEEVKMLRERITRRGLKKNPGCSWIEIKGKVKIFVAGDSSHPQAAKIESLLKRLRLKMKEEGQSPKMQYALINADEAEKEVALCGHSEKLAIAFGILNLQPGKTIRVTKNLRVCGDCHEMAKFISRTSRREIVLRDSNRFHHMKDGNCSCRGFW 1319          

Query:  355 RVFDEIPQPS---VILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYI-CMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            RV D +  P+   V   N  I  Y   G  + A+ +     +S +    Y    V++ C+G+ +L+ G+ +H      G+ +D  +   L+ +Y KCG L EA+ VF  +    V  WN MI  ++    + + + +  +MQ+ G   N+ T   VL   +    + +G+ +HG+  +     +  +G  L+  Y K + I  AR++FD +  ++ + W++MI AYV      + + +F +MV    I+    T+ ++L AC    +LS GR +H YAIK+ FD + M  N +L MY+KCG +  A++ F KM  +  VS++++I+G ++ G + EA+ +F  M+  G +PD  T+  +L AC+   +L+ G   H Y   HG  +   +CN L+DMY+KCG +     VF RM  +DI+SWN MI GY  + L   A+  F  M+    KPD +T   +L AC+    +  G+     +  +   + R  H    +VD+  + G L  A +    +P + D+  W+ + A   +H
Sbjct:  498 RVSDSLAAPAITGVADKNAKINKYCEMGNLKSAMEMVSGAQKSELDLEAYCS--VVELCAGMMSLQDGKXVHSVICDNGVEADGQLGAKLVFMYVKCGDLREARRVFDKLSNGKVFVWNLMINEYAKVRNFREGVYLFGKMQELGIQANSYTFSCVLKCFSALGCVREGEWIHGYLYKLGFGSDNTVGNSLMAFYFKNRRIEXARKVFDELCDRDVISWNSMISAYVSNGLAEKGVEIFRQMV-SLGIDVDLATIINVLMACVAGGNLSLGRALHAYAIKASFDEDVMFCNNVLDMYSKCGDLSSAIQVFKKMGERSVVSWTSMIAGHIREGLSDEAIGLFSEMERDGVNPDAYTITSILHACASSGSLKKGRDIHNYIKEHGMDSSLYVCNTLMDMYAKCGSMEDAHSVFSRMPAKDIVSWNTMIGGYSKNCLPNEALKLFSEMMQKS-KPDSMTIASVLPACASLAALNRGQEIHGHILRNGYFSER--HVANALVDMYVKCGVLVLARLLFDXIPVK-DLISWTVIXAGYGMH 1026          

Query:  199 YSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYA--IKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            ++ T     S+ +  +I   ++KN   L +      K+  L+      + A+RVFD +     + ++ L++ YA N     A   +  +   GVKP  Y + ++LK C     L  G+EIH    + G AS+++  TA+++LYAKC  + EA  +F  M  +D+V+WN ++AG++ +GL    ++++++MQ+ G  P+  T+V +LP VA   +L  GK++H + +R      V L T L+DMYSKC  +  AR IF  +  K  V W++MI  YV  +  +EAM +F +M L +   PT VT+   L AC  L DL RG  VH     +K G D++ M  N+++SMY+KC  +D A + F+K+  K  VS++A+I G  QNG   EAL  F  M      PD  TMV V+PA + L+  +     H   I   F  +  +   L+DMY+KCG ++  R++FD M  R + +WNAMI GYG +GLG +A+  F+ M    IKP+D+TF+ ++SACSHSGLV EG  +F +  ED+ + P M+HY  MVDLLGRAG L EA  FIQ MP E  + V+ A+L ACR+H NIELGE+ + KI        G  VLL+NIY     WD  A V    + +GL+K+PGCS V++   +H F  G  SHPQS +I+  L+ L  ++K  GY  + + +  DVE + KE++L  HSEKLAIA+ +L+  PG  I + KNLRVCGDCH A K I+L+T+REIIVRD+ RFHHFK+G C+C D+W
Sbjct:  223 FNPTTALCTSMQELNQIIPLIIKNG--LYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKM-LDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVM--NSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQNMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFXLNPADGGYHVLLANIYQTASLWDKVAXVXTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSKRIYXFLDTLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGATIHIRKNLRVCGDCHNATKYISLVTRREIIVRDMHRFHHFKNGTCSCGDYW 992          

Query:  307 KVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYA--IKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            K+  L+      + A+RVFD +     + ++ L++ YA N     A   +  +   GVKP  Y + ++LK C     L  G+EIH    + G AS+++  TA+++LYAKC  + EA  +F  M  +D+V+WN ++AG++ +GL    ++++++MQ+ G  P+  T+V +LP VA   +L  GK++H + +R      V L T L+DMYSKC  +  AR IF  +  K  V W++MI  YV  +  +EAM +F +M L +   PT VT+   L AC  L DL RG  VH     +K G D++ M  N+++SMY+KC  +D A + F+K+  K  VS++A+I G  QNG   EAL  F  M      PD  TMV V+PA + L+  +     H   I   F  +  +   L+DMY+KCG ++  R++FD M  R + +WNAMI GYG +GLG  A+  F+ M    IKP+D+TF+ ++SACSHSGLV EG  +F +  ED+ + P M+HY  MVDLLGRAG L EA  FIQ MP E  + V+ A+L ACR+H NIELGE+ + KI        G  VLL+NIY     WD  A V    + +GL+K+PGCS V++   +H F  G  SHPQS +I+  L+ L  ++K  GY  + + +  DVE + KE++L  HSEKLAIA+ +L+  PG  I + KNLRVCGDCH A K I+L+T+REIIVRD+ RFHHFK+G C+C D+W
Sbjct:   97 KLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKM-LDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVM--NSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKXAVXLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQNMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFXLNPADGGYHVLLANIYQTASLWDKVAXVXTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSKRIYXFLDTLGDEIKAAGYVPDTNSI-HDVEADVKEQLLNSHSEKLAIAFGLLNTTPGATIHIRKNLRVCGDCHNATKYISLVTRREIIVRDMHRFHHFKNGTCSCGDYW 832          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSI--CNVLIDMYSKCGKINRGRQVFDRM-VTRDIISWNAMIVGYGIH 1641
            C  +  L + K+IH  L+  ++      F +  V +LY  C QVD A ++FD +P+  ++ WN ++  YA NG  + A+ L   + + G KP   T   +L A +   +L  G+ IH +    G  S V + TAL+D+Y+KCG +  A+ +F  M +K VV+WN+MI G+  +    + +++  +M   G  P   TI+  L   A    L +G  +H    +  L  +V +   L+ MYSKC+ +  A +IF+ +  K  V W+AMI  Y     + EA++ F EM   + I P   T+ S++ A  +L+   + + +H   I+  FD N  V   ++ MYAKCG +  A + FD M+ +   +++A+I G   NG  K A+ +F+ M+     P+  T + V+ ACSH   ++ G    A S    +G + ++     ++D+  + G++         M +   I  + AM+    IH
Sbjct:  168 CGDNADLRRGKEIHGDLI--SSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEM-HSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKXAVXLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFA-SXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQNMPMEPGITVFGAMLGACRIH 643          

Query:  490 KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKE---INPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALL 1932
            K+    +L+ C+  Q L    +I       GL ++    T L+ L+   G   EA  VF  +  K  V ++ ++ G++ +    D      +M+  G  P       +L        L +GK +HG  +    +  +   T ++++Y+KC+ +  A ++FD +  ++ V W+ ++  Y      + AM    E+V+R +     P P+TL ++L A      L  G+ +H Y +++GF+ +  +   ++ MY+KCG +  A   F +M  K  VS++++I G VQN   KEA+ +F  M   GF+P   T++  L AC+ L  L+ G   H        G+D S+ N LI MYSKC +++   ++F+++  +  +SWNAMI+GY  +G    A+S F  M +  IKPD  T + ++ A +   +  + K W + +         +     +VD+  + G +  A      M  E  V  W+A++
Sbjct:   60 KHPAAILLELCTSXQELN---QIIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAM----ELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAK-WIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMD-ERHVTTWNAMI 534          

Query: 1117 ILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWD 2064
            +L  CT   +L++   +    IK+G     +    ++S++   G  ++A R FD +  K  V Y  ++ G  +N    +A   F  M+  G  P +     +L  C   A L+ G   H   I  GF ++      ++++Y+KC +++   ++FDRM  RD++SWN ++ GY  +GL   A+     M   G KPD +T + LL A +  G +  GK   +A          +     +VD+  + G +  A +   +M  +  V  W++++     + + +   EV +K+  +G E T N+ ++  +++     D
Sbjct:   66 LLELCTSXQELNQ---IIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKS-IHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVS-WNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPT-NVTIMEALHACADLGD 375          

Query:  238 AKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDL-LQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSG-FDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQ-LSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            AK++H +L+          FL  K+ + Y     +  + R FD IP+  V  WN ++ AY  +G F  A+  +    L S + P  YT+P VLKAC  L     G++IH     LG   DV+V  +LI +Y++ G +  A+ +F  M  +D  +WNAMI+GF  +    D + +LV+M+  G   +  T+ ++L   AQ+N +S G+ +H + ++  L  ++ +   L++MYSK   + +ARR+FD ++V++ V W++++ AY   +    A+ LF+ M LR  I P  +TL S+     +L+D  + + VH + ++   F  + ++GN ++ MYAK G ID A   F+ + +KD VS++ +I+G  QNG+A EA+ ++  MQ      P+  T V +LPA +H+ ALQ G   H   I +   +D  +   LIDMY KCG+++    +F ++  +  + WNA+I  +G+HG G  A+  F+ ML  G+KPD VTF+ L++ACSHSGLV EG+ +F+ M E + I P ++HY CMVDLLGRAG L +A+ FI+ M    D  VW ALL ACR+H N+E+G+  S+++     E  G  VLLSNIY+  G+W+    VR   + +GL K+PG S +E+N  +  F   +QSHP+  +I+EKL +L   MK LGY  + SFVLQDVE++EKE IL  HSE+LAIA+ I+S  P  PI + KNLRVCGDCH A K I++IT+REIIVRD  RFHHFKDG C+C D+W
Sbjct:   86 AKQLHAYLV--VLGKSQNIFLAAKLVNRYAYLGDLSFSRRTFDSIPRKDVYTWNSMVSAYVRSGRFREALDCFSQFSLTSDLHPDFYTFPPVLKACENLVD---GKKIHCRVLKLGFEWDVFVAASLIHMYSRFGFIYVARKLFDDMPIRDTGSWNAMISGFCQNANAADALDVLVEMRMEGIKMDRVTVASLLTACAQSNDISSGRLIHLYVIKHGLDFDLFVCNALINMYSKFGSLGHARRVFDQMEVRDLVSWNSIVAAYEQNNDPITALELFNAMQLRG-IQPDFLTLVSLASILAQLSDSEKSKSVHGFILRRDWFVEDVVIGNAVVDMYAKLGAIDSARTVFEGLPTKDAVSWNTLITGYAQNGHASEAIEVYRMMQQCKEIIPNHGTWVSILPAYTHVGALQQGMKVHGRVIKNRVYSDVFVGTCLIDMYGKCGRLDDALCLFSQVPRKSSVPWNALISCHGVHGHGEKALQLFNDMLDEGVKPDHVTFVSLMAACSHSGLVNEGQSFFHTMQEQYGIKPSLKHYGCMVDLLGRAGHLNKAYSFIENMSVRPDASVWGALLGACRIHGNVEMGKIASERLFEVDSENVGYYVLLSNIYANFGKWEGVEKVRSLARNRGLTKTPGWSSIEVNNNVDVFYTANQSHPKCEEIYEKLRDLTARMKSLGYIPDLSFVLQDVEDDEKEHILNSHSERLAIAFGIISTAPKTPIRIFKNLRVCGDCHNATKFISVITEREIIVRDSNRFHHFKDGTCSCGDYW 843          

Query: 1141 TDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQL-SGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK--HWFNAM-SEDFNITPRMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLE 2007
            T++   +++H Y +  G   N  +   +++ YA  G +  + R FD +  KD  ++++++S  V++G  +EAL  F    L S   PD  T   VL AC +L     G   H   +  GF  D  +   LI MYS+ G I   R++FD M  RD  SWNAMI G+  +     A+     M   GIK D VT   LL+AC+ S  ++ G+  H +      DF++      ++C  ++++  + G L  A     +M    D+  W++++AA   +N+     E+   +Q +G++
Sbjct:   81 TNVHHAKQLHAYLVVLGKSQNIFLAAKLVNRYAYLGDLSFSRRTFDSIPRKDVYTWNSMVSAYVRSGRFREALDCFSQFSLTSDLHPDFYTFPPVLKACENLV---DGKKIHCRVLKLGFEWDVFVAASLIHMYSRFGFIYVARKLFDDMPIRDTGSWNAMISGFCQNANAADALDVLVEMRMEGIKMDRVTVASLLTACAQSNDISSGRLIHLYVIKHGLDFDL------FVCNALINMYSKFGSLGHARRVFDQMEVR-DLVSWNSIVAAYEQNNDPITALELFNAMQLRGIQ 365          

Query:  190 YHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEI-PQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALG-LASDVYVCTALIDLYAKCGG-LAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQC---IAYARRIFDAIDVKNEVCWSAMIGAYVICDSM-REAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y +   +CIRS++    K +H  L  +  +L+    LL  +  LY        A+ +F+ +  + +++ W+ ++  +A N     AI  + D+L+ G  P +Y +  V++ACS  + +  G+ I       G L SDV V  +LID++AK GG L EA  VF  M   D V W  MI  F+  G   + I + V M  +G  P+   +  V+    +  +LS G+ +H + +R  L+    +G  L+DMY+KC     +  AR++FD +   N + W+A+I  YV       EA+ LF EM +   + P   T  SIL+AC  L+DL +G ++H  A+KSG      VGN++++MY+K G ++DA + FD +  K+ +SY+ I+    ++  A+EA  +FH +Q +G+     T   +L   + + A   G   HA  I  G  ++  ICN L+ MYS+CG I+    VF+ M   ++ISW +MI G+  HG   AA+  F+ ML AGIKP+ +T+I +LSACSH+GLV EG   F  M +   + PRMEHY CMVDLLGR+G L EA  FI  MPF AD  +W   L ACRVH NIELG+  +K I  +    +    LLSN+Y++ GRW++ A VR   K + L K  G SW+E+   IH F  GD SHP++ +I+++L++L   +K+LGY     FVL DVEEE+K   L  HSEK+A+A+ ++S    KPI V KNLRVCGDCH AIK I+  T REI+VRD  RFHHFKDG C+C ++W
Sbjct:   65 YSLLIKSCIRSRNFDLXKLVHDRLAHS--QLEPDQVLLNSLISLYSKSGDWKKANSIFENMGSERNLVSWSAMVSCFANNDMGFEAISTFLDMLEHGFYPNEYCFASVIRACSNARNIGIGKVIFGSVIKGGYLGSDVCVGCSLIDMFAKGGGDLGEAYKVFEEMPETDAVTWTLMITRFAQMGFPREAIGLYVDMLLSGFMPDQFALSGVISACTKLESLSLGQQLHSWVIRSGLALGHCVGCCLVDMYAKCAADGSMNDARKVFDRMPNHNVMSWTAIINGYVQSGKGDEEAIKLFVEM-MSGHVPPNHFTFSSILKACANLSDLCKGEQIHSLAVKSGLASVNCVGNSLITMYSKSGQVEDARKSFDVLYEKNLISYNTIVDAYAKHLDAEEAFGLFHEIQDTGYGASAFTFSSLLSGAASICAAGKGEQIHARIIKSGLESNQIICNXLVSMYSRCGNIDAAFLVFNEMEDWNVISWTSMITGFAKHGYAAAAVEMFNKMLEAGIKPNXITYIAVLSACSHAGLVDEGWKHFKEMQKKHGVVPRMEHYACMVDLLGRSGSLVEALEFINSMPFTADELIWRTFLGACRVHGNIELGKHAAKMIIEQNPRDSAAYSLLSNLYASTGRWEEVAKVRKYMKEKYLIKEVGSSWIEVKNKIHKFHVGDTSHPKAKEIYDELDQLGSKIKKLGYVPNTDFVLHDVEEEQKGFYLFQHSEKIAVAFGLISTSKSKPIRVFKNLRVCGDCHTAIKYISEATGREIVVRDSNRFHHFKDGRCSCNEYW 845          

Query:  427 GPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGM-LYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRS-LSGEVVLGTGLLDMYSK-CQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKC---GIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYA-KEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLE 2007
            G   +AI     L Q G+ P   TY  ++K+C   +  +  + +H       L  D  +  +LI LY+K G   +A ++F  M   +++V+W+AM++ F+ + +  + I   + M + G  PN     +V+   + A  +  GK + G  ++   L  +V +G  L+DM++K    +  A ++F+ +   + V W+ MI  +      REA+ L+ +M+L     P    L  ++ ACTKL  LS G+++H + I+SG  L   VG  ++ MYAKC   G ++DA + FD+M + + +S++AII+G VQ+G   +EA+ +F  M      P+  T   +L AC++L+ L  G   H+ ++  G  +   + N LI MYSK G++   R+ FD +  +++IS+N ++  Y  H     A   FH +   G      TF  LLS  +      +G+   +A      +         +V +  R G +  A +   +M  + +V  W++++     H       E+  K+   G++
Sbjct:   41 GHLRKAITTLDLLAQRGIHPDLPTYSLLIKSCIRSRNFDLXKLVHDRLAHSQLEPDQVLLNSLISLYSKSGDWKKANSIFENMGSERNLVSWSAMVSCFANNDMGFEAISTFLDMLEHGFYPNEYCFASVIRACSNARNIGIGKVIFGSVIKGGYLGSDVCVGCSLIDMFAKGGGDLGEAYKVFEEMPETDAVTWTLMITRFAQMGFPREAIGLYVDMLL-SGFMPDQFALSGVISACTKLESLSLGQQLHSWVIRSGLALGHCVGCCLVDMYAKCAADGSMNDARKVFDRMPNHNVMSWTAIINGYVQSGKGDEEAIKLFVEMMSGHVPPNHFTFSSILKACANLSDLCKGEQIHSLAVKSGLASVNCVGNSLITMYSKSGQVEDARKSFDVLYEKNLISYNTIVDAYAKHLDAEEAFGLFHEIQDTGYGASAFTFSSLLSGAASICAAGKGEQ-IHARIIKSGLESNQIICNXLVSMYSRCGNIDAAFLVFNEME-DWNVISWTSMITGFAKHGYAAAAVEMFNKMLEAGIK 571          

Query:  172 YVYQCHY-HIYSTTCIRSKSLPQAKKIHQHLLKN----TTRLKDTSFLLEKVAH-----------LYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGML-YKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y +Q  + H   T  +RS       K H +LL N    + R+ +   + +K+              Y    ++  A ++FD  P  + I W+ LI  Y  N     A  L++ +   G KP++YT   VL+ CS L  L+ G  +H +       ++++V T L+D+YAKC  ++EA+ +F  +   K+ V W  M+ G+S +G     ++    M+  G   N  T  +VL   A   A S G  +HG  ++  L   V + + L+DMY KC  +  A++   +++V N V W++MI   V      EA++LF +M  R E+     T  S+L +   + D++    +HC  IK+GFD+  +VGN ++ MYAK G ID AV  F  M+ KD +S++++I+G V+NG  ++AL +F  M+ +G  PD   +   L A + L  L+ G   HA  I  G     S+ N  + MY+KCG I    +VFD M  +D+I+W A+IVGY  +G G  ++  +  M+  G +PD +TFIGL+ ACSH+GL+ +G+++F  MS  + I P  EHY CM+DLLGR+G L EA   + KM  E D  VW ALLAACRVH NIELGE  +  +           V LSN+YSA  RW+DAA +R   K +G+ K PGCSW+E N  +H F+  D+SH ++A+I+ K++E+++ +K  GY  + +F L D+++E KE  L YHSEKLA+A+ +L+  PG PI + KNLRVCGDCH A+K I+ +  R II+RD   FHHFK+G C+C D+W
Sbjct:   86 YSHQSRFNHRGLTRFLRSTVDSTESKFHSNLLLNELSKSGRVDEARQMFDKMPSRDEFSWNTMIAAYANSGRLAEAKQLFDATPSKNSITWSSLISGYCRNESESEAFELFWRMQFEGHKPSQYTLGSVLRLCSTLGLLQRGALVHGYMTKTQFDNNIFVVTGLVDMYAKCKRISEAEYLFETLFDRKNHVLWTVMLTGYSQNGDGFKAMKFFRDMRAEGVESNQFTFPSVLTASASVLAHSFGAQVHGCVVQSGLGANVFVQSSLVDMYVKCGDLNSAKKALRSMEVDNVVSWNSMIVGCVRQGFAEEALSLFKDMRSR-EMKIDHFTYPSVLNSFAVMKDMTNAMSIHCLIIKTGFDVYQLVGNALVDMYAKQGNIDAAVEVFKCMSDKDVISWTSLITGYVRNGSHEKALRLFCEMRTAGIYPDQFVIASALSASAELTVLEFGQQIHANFIKSGLQASLSVDNSFVAMYAKCGCIEDANKVFDSMQVQDVITWTALIVGYAQNGRGKESLKFYDQMILTGAEPDFITFIGLIFACSHAGLLEKGRYYFELMSRVYGIQPGSEHYACMIDLLGRSGKLNEAEALVNKMVVEPDGTVWKALLAACRVHGNIELGERAAMNLFKLEPLNAVPYVQLSNMYSAASRWEDAARIRRLMKSKGILKEPGCSWIETNSQVHTFMSEDRSHSRTAEIYSKVDEIMMLIKEAGYVPDMNFALHDMDKEGKELGLAYHSEKLAVAFGLLTTPPGAPIRIFKNLRVCGDCHTAMKFISKVYLRHIILRDSNCFHHFKEGNCSCDDYW 884          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            C     L   K++H   +K+   L   +F+   +  LY  C  ++LA RV   +P+  V+ WN L+  YA  G  ++++ L+  + +S ++ +K T   VLK C+    L  G+ +H     +G   D ++  +L+D+Y+KCG   +A   FR +   DVVAW+A+I+     G + +  Q+  +M   G SPN  T+ +++        L  G+++H F+ +     ++ +   L+ MY K   +    ++F+A+   + + W+A++      +       +F +M++ + + P   +  S+LR C+ L D+  G+++H + IK+  D N  VG  ++ MYAK   ++DAV+ F++++++D  +++ II+G  Q   A+E++  F+ MQ  G  P+  ++ G L ACS  A L++G   H+  I  G   D  + + L+DMY+KCG I+    +F+ +V+RD +SWN M+ GY  +G G  A+  F  ML  G  P+++TFIG+L ACSH GLV EGK  F+++S  F ITP +EHY CMVD+LGRAG   E   FI+         +W  +L AC++H N+E GE  ++++     E     +LLSNI++  GRWDD + VR   + QG+KK PGCSWVE++G ++ FV  D +HP+   IH KLEEL   +  LGY  E   VL  + E EK+  L YHSE+LA+ +A++S    K I + KNLR+CGDCH  +K+++ +T REI+VRD+ RFHHFK+G C+C DFW
Sbjct:  221 CSLCSDLGFGKQLHAEAVKHGLLLD--AFVGSALVGLYAKCGDMELADRVLFCMPEQDVVSWNALLNGYAQEGDGKKSLELFCRMTESEIRLSKSTLSTVLKGCANSGNLSGGQFLHSLVVKIGFQIDEFLGCSLVDMYSKCGMAVDAVKAFRTIENPDVVAWSAIISCLDQQGQWQEVPQLFREMISTGISPNKFTLSSIISAATDLXDLHFGESIHAFAWKYGCEADISVSNALITMYMKSGRLLDGAQVFEAMTNPDLISWNALLSGAHNHELSDLGPRVFXQMLV-EGLKPNMYSFISVLRCCSSLLDVDLGKQIHSHIIKTNLDDNDFVGTALIDMYAKGRFVEDAVKAFNRLSNRDLFTWTVIITGYAQTDQAEESVACFNKMQQEGVKPNEFSIAGCLSACSRTAMLENGRQLHSMVIKSGHLEDLFVTSALVDMYAKCGCISDAEDIFEGLVSRDTVSWNIMVCGYSQYGQGEKALEAFSTMLDEGAIPNEITFIGVLXACSHLGLVXEGKKHFDSLSNVFGITPTIEHYACMVDILGRAGKFNEIETFIETKELTPYAIIWETVLGACKMHGNVEFGETAARRLFELKPEMDSTYILLSNIFAVKGRWDDVSKVRKLMQSQGVKKEPGCSWVEVDGQVNIFVSQDGTHPRIGDIHLKLEELGEKLNSLGYIPETEDVLHRITEREKKEHLQYHSERLALGFALISTSHPKTIRIFKNLRICGDCHDXMKLVSDVTNREIVVRDIRRFHHFKNGTCSCKDFW 987          

Query:  187 HYHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAM-----SEDFNITPRMEHYICMVDLLGRAGFLAEA 1872
            HY     TC+  +SL + K IH  ++K    +   S L   + ++Y  C     A  V D +P+  V+ W  LI+ +   G    A+ L+ ++ + G K   +     LKACS    L  G+++H  A   GL  D +V +AL+ LYAKCG +  A  V   M  +DVV+WNA++ G++  G    ++++  +M ++    + ST+  VL   A +  LS G+ +H   ++     +  LG  L+DMYSKC     A + F  I+  + V WSA+I         +E   LF EM+    I+P   TL SI+ A T L DL  G  +H +A K G + +  V N +++MY K G + D  + F+ M + D +S++A++SG   +  +     +F  M + G  P++ + + VL  CS L  +  G   H++ I      +  +   LIDMY+K   +    + F+R+  RD+ +W  +I GY        +++ F+ M   G+KP++ +  G LSACS + ++  G+   + +      ED  +T        +VD+  + G +++A
Sbjct:  112 HYSGMLRTCVSLRSLNEGKAIHGQVIKEG--IDPDSHLWVSLVNVYAKCGDSGYARXVLDVMPERDVVSWTSLIQGFVVEGSGVDAVKLFCEMKKDGTKANDFALATGLKACSLCSDLGFGKQLHAEAVKHGLLLDAFVGSALVGLYAKCGDMELADRVLFCMPEQDVVSWNALLNGYAQEGDGKKSLELFCRMTESEIRLSKSTLSTVLKGCANSGNLSGGQFLHSLVVKIGFQIDEFLGCSLVDMYSKCGMAVDAVKAFRTIENPDVVAWSAIISCLDQQGQWQEVPQLFREMI-STGISPNKFTLSSIISAATDLXDLHFGESIHAFAWKYGCEADISVSNALITMYMKSGRLLDGAQVFEAMTNPDLISWNALLSGAHNHELSDLGPRVFXQMLVEGLKPNMYSFISVLRCCSSLLDVDLGKQIHSHIIKTNLDDNDFVGTALIDMYAKGRFVEDAVKAFNRLSNRDLFTWTVIITGYAQTDQAEESVACFNKMQQEGVKPNEFSIAGCLSACSRTAMLENGRQLHSMVIKSGHLEDLFVTS------ALVDMYAKCGCISDA 669          

Query:  190 YHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            Y +    CIR+     A  +H  +LK    L    F    + ++Y+    +  A+ +FDE+ + +VI +  LI+ ++  G F  A+ L+  L + G +  ++ +  +LK        E    +H     L   S  +V TALID Y+ CG +  A+ VF  ++ KD+VAW  M+A ++ +G  ++ +++  QM+  G  PN  T    L   A   AL+ GK++HG  ++    G++ +GT LLD+Y+K   I  AR++F  +   + V WS M+  Y   D   EA+ LF  M  +  + P   T  S L+AC  +  L  G ++HC+  K G D +  V N ++ +YAKCG IDD++  F +  +++ VS++ +I G  Q G  ++AL++F  M     +    T    L A S LAAL+ G   H+ ++   +  DT + N LIDMY+KCG I   R VFD++  RD +SWN MI GY +HGL + A+  F  M     KP+ +TF+G+LSACS++GL+ +G+ +F++M +D+++ P +EHY CMV LLGR+G L +A   I ++PFE  + VW ALL AC +HN++ELG   +K +     +     VLLSNIY+   RWD+ AYVR   K +G+KK PG SW+E  G +H F  GD SHP    I+  LE L +   + G+    + +L DV E+EKER+L  HSE+LA+A+ ++    G PI + KNLR+C DCHA +K+I+ I +R+IIVRDL RFHHF+DG+C+C D+W
Sbjct:  167 YGVVLQHCIRNGDARSAMGLHCEILKKGGCLD--LFADNILLNMYVKAGMLVDAANLFDEMSERNVISFVTLIQGFSDYGRFVDAVELFSGLHREGHELNQFVFTTILKLLVRTGWAELVWTVHACIHKLAHGSSAFVGTALIDAYSVCGYVNVARDVFDEVVCKDMVAWTGMVACYAENGCSEEALELFSQMRVIGFRPNNYTFTGALKACAGLEALNGGKSVHGCVIKSCYEGDLYVGTALLDLYTKFGDIEEARQVFQEMPKNDVVPWSLMVSRYAQSDRCEEALDLFCRM-RQAFVVPNQFTYASTLQACATMEHLDFGMQIHCHVTKVGIDSDVYVSNALMGVYAKCGKIDDSMDLFVESPNRNDVSWNTMIVGYAQLGDGEKALMLFSGMIRCQVEATEVTYSSALHASSGLAALESGVQIHSVTVKTIYDKDTVVGNSLIDMYAKCGNIKDARLVFDKLKQRDEVSWNTMISGYSMHGLALEALKVFEMMQETNCKPNKLTFVGVLSACSNAGLLDQGQAYFDSMVQDYDVEPCIEHYTCMVWLLGRSGHLDKAVKLINEIPFEPSIMVWRALLGACVIHNDVELGRTAAKHVLEMDPQDEATHVLLSNIYATAKRWDNVAYVRKNMKRKGVKKEPGLSWIENQGTVHYFAVGDTSHPDMKLINGMLEWLKLRTLKAGHVPNCNAILLDVAEDEKERLLWVHSERLALAFGLVRAPSGSPIRIIKNLRICMDCHATVKLISKIVQRDIIVRDLNRFHHFQDGVCSCGDYW 940          

Query:  493 YTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            + Y  VL+ C       +   +H      G   D++    L+++Y K G L +A  +F  M  ++V+++  +I GFS +G + D +++   + + G   N      +L  + +         +H    + +      +GT L+D YS C  +  AR +FD +  K+ V W+ M+  Y       EA+ LF +M +     P   T    L+AC  L  L+ G+ VH   IKS ++ +  VG  +L +Y K G I++A + F +M   D V +S ++S   Q+   +EAL +F  M+ +   P+  T    L AC+ +  L  G   H +    G  +D  + N L+ +Y+KCGKI+    +F     R+ +SWN MIVGY   G G  A+  F  M+   ++  +VT+   L A S    +  G    +   +       +     ++D+  + G + +A +   K+  + D   W+ +++   +H
Sbjct:  165 HAYGVVLQHCIRNGDARSAMGLHCEILKKGGCLDLFADNILLNMYVKAGMLVDAANLFDEMSERNVISFVTLIQGFSDYGRFVDAVELFSGLHREGHELNQFVFTTILKLLVRTGWAELVWTVHACIHKLAHGSSAFVGTALIDAYSVCGYVNVARDVFDEVVCKDMVAWTGMVACYAENGCSEEALELFSQMRV-IGFRPNNYTFTGALKACAGLEALNGGKSVHGCVIKSCYEGDLYVGTALLDLYTKFGDIEEARQVFQEMPKNDVVPWSLMVSRYAQSDRCEEALDLFCRMRQAFVVPNQFTYASTLQACATMEHLDFGMQIHCHVTKVGIDSDVYVSNALMGVYAKCGKIDDSMDLFVESPNRNDVSWNTMIVGYAQLGDGEKALMLFSGMIRCQVEATEVTYSSALHASSGLAALESGVQIHSVTVKTIYDKDTVVGN-SLIDMYAKCGNIKDARLVFDKLK-QRDEVSWNTMISGYSMH 647          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            CI+SKSL +AKKIHQH LKNT+     S +L K+  LY++CNQV LA R+FDEIP PSVILWN +IRAYAWNGPF+ AI LY+ +L  GV+P KYTYPFVLKACSGL A+E G EIH HAK  GL SDV+VCTAL+D YAKCG L EAQ +F  M ++DVVAWNAMIAG SL+GL DD +Q+++QMQ+ G  PN+STIV VLPTV +A AL  GKA+HG+ +RRS    VV+GTGLLDMY+KCQC+ YAR+IFD + V+NEV WSAMIG YV  D M+EA+ LFD+M+L+  ++PTPVTLGS+LRAC KLTDLSRGR++HCY IK G  L+ ++GNT+LSMYAKCG+IDDA+RFFD+MN KD+VS+SAI+SGCVQNG A  AL IF  MQLSG DPDL TM+GVLPACSHLAALQHG C H Y IV GF TDT ICN LIDMYSKCGKI+  R+VF+RM   DI+SWNAMI+GYGIHGLGM A+  FH +LA G+KPDD+TFI LLS+CSHSGLV EG+ WF+AMS DF+I PRMEH ICMVD+LGRAG + EAH FI+ MPFE DVR+WSALL+ACR+H NIELGEEVSKKIQ  G E TGN VLLSNIYSA GRWDDAA++RI QK  GLKK PGCSW+EINGI+H FVGGDQSH Q +QI+ KLEELLV+MKRLGY AE SFV QDVEEEEKE+ILLYHSEKLAIA+ IL+L+ G+PILVTKNLRVCGDCH AIK +TLITKREI VRD  RFHHFK+G CNC DFW
Sbjct:   18 CIQSKSLTEAKKIHQHFLKNTSNAD--SSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVASDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGSVLDILLGNTLLSMYAKCGVIDDAIRFFDEMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHGFCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMDRHDIVSWNAMIIGYGIHGLGMEALGLFHDLLALGLKPDDITFICLLSSCSHSGLVMEGRLWFDAMSRDFSIVPRMEHCICMVDILGRAGLIDEAHHFIRNMPFEPDVRIWSALLSACRIHKNIELGEEVSKKIQSLGPESTGNFVLLSNIYSAAGRWDDAAHIRITQKDWGLKKIPGCSWIEINGIVHAFVGGDQSHLQLSQINRKLEELLVEMKRLGYQAECSFVFQDVEEEEKEQILLYHSEKLAIAFGILNLKAGRPILVTKNLRVCGDCHTAIKFMTLITKREITVRDANRFHHFKNGTCNCGDFW 785          

Query:  490 KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGA---YVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQL-SGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITP--RMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            K  Y  +L+AC   ++L   ++IHQH       +D  V   L  LY  C  +  A+ +F  +    V+ WN +I  ++ +G +D  I +   M   G  PN  T   VL   +   A+  G  +H  +    L  +V + T L+D Y+KC  +  A+R+F ++  ++ V W+AMI     Y +CD   +A+ L  +M   + I P   T+  +L    +   L  G+ +H Y ++  FD   +VG  +L MYAKC  +  A + FD M  ++ VS+SA+I G V +   KEAL +F  M L    DP   T+  VL AC+ L  L  G   H Y I  G   D  + N L+ MY+KCG I+   + FD M  +D +S++A++ G   +G    A+S F  M  +GI PD  T +G+L ACSH   +  G       S  + I      +  IC  ++D+  + G ++ A     +M    D+  W+A++    +H
Sbjct:    8 KNNYLHLLEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCD---DAVQLIMQM-QEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVASDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGSVLDILLGNTLLSMYAKCGVIDDAIRFFDEMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHG-----FCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMD-RHDIVSWNAMIIGYGIH 492          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            CI+SKSL +AKKIHQH LKNT+     S +L K+  LY++CNQV LA R+FDEIP PSVILWN +IRAYAWNGPF+ AI LY+ +L  GV+P KYTYPFVLKACSGL A+E G EIH HAK  GL SDV+VCTAL+D YAKCG L EAQ +F  M ++DVVAWNAMIAG SL+GL DD +Q+++QMQ+ G  PN+STIV VLPTV +A AL  GKA+HG+ +RRS    VV+GTGLLDMY+KCQC+ YAR+IFD + V+NEV WSAMIG YV  D M+EA+ LFD+M+L+  ++PTPVTLGS+LRAC KLTDLSRGR++HCY IK G  L+ ++GNT+LSMYAKCG+IDDA+RFFD MN KD+VS+SAI+SGCVQNG A  AL IF  MQLSG DPDL TM+GVLPACSHLAALQHG C H Y IV GF TDT ICN LIDMYSKCGKI+  R+VF+RM   DI+SWNAMI+GYGIHGLGM A+  FH +LA G+KPDD+TFI LLS+CSHSGLV EG+ WF+AMS DF+I PRMEH ICMVD+LGRAG + EAH FI+ MPFE DVR+WSALL+ACR+H NIELGEEVSKKIQ  G E TGN VLLSNIYSA GRWDDAA++RI QK  GLKK PGCSW+EINGI+H FVGGDQSH Q +QI+ KLEELLV+MKRLGY AE SFV QDVEEEEKE+ILLYHSEKLAIA+ IL+L+ G+PILVTKNLRVCGDCHAAIK +T+ITKREI VRD  RFHHFK+G CNC DFW
Sbjct:   18 CIQSKSLTEAKKIHQHFLKNTSNAD--SSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVXSDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGXVLDILLGNTLLSMYAKCGVIDDAIRFFDXMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHGFCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMDRHDIVSWNAMIIGYGIHGLGMEALGLFHDLLALGLKPDDITFICLLSSCSHSGLVMEGRLWFDAMSRDFSIVPRMEHCICMVDILGRAGLIDEAHHFIRNMPFEPDVRIWSALLSACRIHKNIELGEEVSKKIQSLGPESTGNFVLLSNIYSAAGRWDDAAHIRITQKDWGLKKIPGCSWIEINGIVHAFVGGDQSHLQLSQINRKLEELLVEMKRLGYQAECSFVFQDVEEEEKEQILLYHSEKLAIAFGILNLKAGRPILVTKNLRVCGDCHAAIKFMTVITKREITVRDANRFHHFKNGTCNCGDFW 785          

Query:  490 KYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGA---YVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQL-SGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITP--RMEHYIC--MVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVH 1950
            K  Y  +L+AC   ++L   ++IHQH       +D  V   L  LY  C  +  A+ +F  +    V+ WN +I  ++ +G +D  I +   M   G  PN  T   VL   +   A+  G  +H  +    L  +V + T L+D Y+KC  +  A+R+F ++  ++ V W+AMI     Y +CD   +A+ L  +M   + I P   T+  +L    +   L  G+ +H Y ++  FD   +VG  +L MYAKC  +  A + FD M  ++ VS+SA+I G V +   KEAL +F  M L    DP   T+  VL AC+ L  L  G   H Y I  G   D  + N L+ MY+KCG I+   + FD M  +D +S++A++ G   +G    A+S F  M  +GI PD  T +G+L ACSH   +  G       S  + I      +  IC  ++D+  + G ++ A     +M    D+  W+A++    +H
Sbjct:    8 KNNYLHLLEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCD---DAVQLIMQM-QEEGICPNSSTIVGVLPTVGEAKALGHGKALHGYCVRRSFDNGVVVGTGLLDMYAKCQCLLYARKIFDVMGVRNEVSWSAMIGGYVXSDCMKEALELFDQMILKDAMDPTPVTLGSVLRACAKLTDLSRGRKLHCYIIKLGXVLDILLGNTLLSMYAKCGVIDDAIRFFDXMNPKDSVSFSAIVSGCVQNGNAAVALSIFRMMQLSGIDPDLTTMLGVLPACSHLAALQHG-----FCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRMD-RHDIVSWNAMIIGYGIH 492          

Query: 1069 MVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGK 1767
            M LR E+    + L   L AC +   L+  +++H + +K+  + ++ V + +  +Y  C  +  A R FD++ +   + ++ II     NG    A+ ++H M   G  P+  T   VL ACS L A++ G   H+++ + G  +D  +C  L+D Y+KCG +   +++F  M  RD+++WNAMI G  ++GL   A+     M   GI P+  T +G+L     +  +  GK
Sbjct:    1 MPLRXEVKNNYLHL---LEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPTVGEAKALGHGK 230          

Query:  277 RLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLY--KDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            R+ D+     ++A  +I+ N++ LA  VFD+IP+PSV+LWN++IR YAW+GPF+++I+LY  +LQ GV PT +T+PF+LKACS LQAL+ GR IH HA  LGL+ D+YV TAL+ +YAKCG L +AQT+F  + +  +D+VAWNAMIA FS H L+  TI  + QMQ+AG +PN+ST+V++LPT+ QANAL QGKA+H + +R      VVL T LLDMY+KC  + YAR+IF+ ++ KN+VCWSAMIG YV+ DS+ +A+AL+D+M+    +NPTP TL ++LRAC +LTDL RG+++HC+ IKSG DL+T VGN+++SMYAKCGI+D+AV F D+M +KDTVSYSAIISGCVQNGYA++ALLIF  MQ SG  P L TM+ +LPACSHLAALQHG C H Y++V GF  DTSICN +IDMYSKCGKI   R++FDRM  RDIISWN MI+GYGIHGL + A+S F  + A G+KPDDVT I +LSACSHSGLVTEGK+WF++MS++FNI PRM HYICMVDLL RAG L EA+ FIQ+MPF  +VR+W ALLAACR H NIE+GE+VSKKIQ  G EGTGN VL+SNIYS+VGRWDDAAY+R  Q+  G KKSPGCSWVEI+G+IH F+GG QSHPQSA I++KL+ELLV MK+LGY A++SFVL DVEEEEKE+ILLYHSEK+AIA+ IL+  P   ILVTKNLR+C DCH+AIK ITL+T+REI VRD +RFHHFKDGICNC DFW
Sbjct:   36 RVSDSDAAATQLARYHISRNEIQLARHVFDQIPKPSVVLWNMMIRTYAWSGPFQQSIYLYLHMLQLGVTPTNFTFPFLLKACSSLQALQLGRLIHTHAHILGLSMDLYVSTALLHMYAKCGHLYQAQTLFNSISHQDRDIVAWNAMIAAFSFHALHAQTIHSVAQMQQAGVTPNSSTLVSILPTIGQANALHQGKAIHAYYIRNFFFDNVVLQTALLDMYAKCHLLFYARKIFNTVNKKNDVCWSAMIGGYVLHDSISDALALYDDMLCIYGLNPTPATLATMLRACAQLTDLKRGKKLHCHMIKSGMDLDTTVGNSLISMYAKCGIMDNAVGFLDEMIAKDTVSYSAIISGCVQNGYAEKALLIFRQMQSSGIAPYLETMIALLPACSHLAALQHGTCCHGYTVVRGFTNDTSICNAIIDMYSKCGKITISREIFDRMQNRDIISWNTMIIGYGIHGLCVEALSLFQELQALGLKPDDVTLIAVLSACSHSGLVTEGKYWFSSMSQNFNIKPRMAHYICMVDLLARAGNLDEAYTFIQRMPFVPNVRIWGALLAACRTHKNIEMGEQVSKKIQLLGPEGTGNFVLMSNIYSSVGRWDDAAYIRSIQRHHGYKKSPGCSWVEISGVIHVFIGGHQSHPQSASINKKLQELLVQMKKLGYRADSSFVLHDVEEEEKEQILLYHSEKVAIAFGILNTSPSSRILVTKNLRICVDCHSAIKFITLLTEREITVRDASRFHHFKDGICNCQDFW 785          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGK 855
            C +   L + KK+H H++K+   L  T  +   +  +Y  C  +D A    DE+     + ++ +I     NG  E+A+ ++  +  SG+ P   T   +L ACS L AL+ G   H +    G  +D  +C A+ID+Y+KCG +  ++ +F  M  +D+++WN MI G+ +HGL  + + +  ++Q  G  P+  T++AVL   + +  +++GK
Sbjct:  322 CAQLTDLKRGKKLHCHMIKSGMDLDTT--VGNSLISMYAKCGIMDNAVGFLDEMIAKDTVSYSAIISGCVQNGYAEKALLIFRQMQSSGIAPYLETMIALLPACSHLAALQHGTCCHGYTVVRGFTNDTSICNAIIDMYSKCGKITISREIFDRMQNRDIISWNTMIIGYGIHGLCVEALSLFQELQALGLKPDDVTLIAVLSACSHSGLVTEGK 534          

Query:  208 TCIRSKSLPQAKKIHQHLLKNTTRLKDTSFL-----LEKVAHLYITCNQVDLASRVFDEIPQ--PSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLH-GLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAID-VKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKE--INPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGD-QSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +CI+SKSL + K IHQHLLK   R  +T+        EK+  LYI C+++ +A  VFD++P    +V+LWNLLIRAYAWNGP+E AI LYY +L  G+ P ++T+PFVLKACS L+    GREIH   K L L S+VYV TAL+D YAKCG L +A+ VF  M  +DVVAWN+MI+GFSLH G YD+  ++LVQMQ    SPN+STIV VLP VAQ N+L  GK +HGF +RR   G+VV+GTG+LD+Y KCQCI YARRIFD +  VKNEV WSAM+GAYV+CD MREA+ LF ++++ K+  I  + VTL +++R C  LTDLS G  +HCYAIKSGF L+ MVGNT+LSMYAKCGII+ A+RFF++M+ +D VS++AIISG VQNG ++E L +F  MQLSG +P+ AT+  VLPAC+HLA L +G+C H Y+I+ GF  DT ICN LIDMY+KCGKI+  R+VFDRM  R I+SWN MI+ YGIHG+G+ A+  F +M + G+KPDDVTFI L+SACSHSGLV EGK+WFNAM++DF I PRMEHY CMVDLL RAG   E H FI+KMP E DVRVW ALL+ACRV+ N+ELGE VSKKIQ  G E TGN VLLSN+YSAVGRWDDAA VR  QK QG +KSPGCSW+EI+G++H F+GG  +SHPQ  QI  KL+ELLV+MKRLGY AE+S+V QDVEEEEKER+LLYHSEKLAIA+ ILSL P K I+VTKNLRVCGDCH AIK I+L+TKR+I VRD +RFHHFKDGICNC DFW
Sbjct:   18 SCIQSKSLFRGKLIHQHLLKCLHRTHETNLTNFDVPFEKLVDLYIACSELKIARHVFDKMPHRPKNVVLWNLLIRAYAWNGPYEEAIDLYYKMLGYGITPNRFTFPFVLKACSALKEASEGREIHCDIKRLRLESNVYVSTALVDFYAKCGCLDDAKEVFDKMHKRDVVAWNSMISGFSLHEGSYDEVARLLVQMQN-DVSPNSSTIVGVLPAVAQVNSLRHGKEIHGFCVRRGFVGDVVVGTGILDVYGKCQCIDYARRIFDMMGIVKNEVTWSAMVGAYVVCDFMREALELFCQLLMLKDDVIVLSAVTLATVIRVCANLTDLSTGTCLHCYAIKSGFVLDLMVGNTLLSMYAKCGIINGAMRFFNEMDLRDAVSFTAIISGYVQNGNSEEGLRMFLEMQLSGINPEKATLASVLPACAHLAGLHYGSCSHCYAIICGFTADTMICNALIDMYAKCGKIDTARKVFDRMHKRGIVSWNTMIIAYGIHGIGLEALLLFDNMQSEGLKPDDVTFICLISACSHSGLVAEGKYWFNAMTQDFGIIPRMEHYACMVDLLSRAGLFKEVHSFIEKMPLEPDVRVWGALLSACRVYKNVELGEGVSKKIQKLGPESTGNFVLLSNMYSAVGRWDDAAQVRFTQKEQGFEKSPGCSWIEISGVVHTFLGGGYRSHPQLTQISNKLDELLVEMKRLGYQAESSYVFQDVEEEEKERVLLYHSEKLAIAFGILSLSPDKHIIVTKNLRVCGDCHTAIKFISLVTKRDITVRDASRFHHFKDGICNCGDFW 799          

Query:  187 HYHIYSTTCIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQ-KAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSG---EVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            H   +ST  +R +  P     H+        +KD     +++   +I   Q+ LA +VFD IP P    +N LIRAY+W GPF  AI LY  +L   V P KYT+PFVLKACS L  L AGR IH HA A+GL +D++V TALIDLY +C     A  VF  M  +DVVAWNAM+AG++ HG+Y   I  L+ MQ + G  PNAST+V++LP +AQ  AL QG ++H + LR  L     +V++GT LLDMY+KC+ + YA R+F  + V+NEV WSA+IG +V+CD M EA  LF +M++      +  ++ S LR C  L DL  G ++H    KSG   +   GN++LSMYAK G+I++A   FD++  KDT+SY A++SG VQNG A+EA L+F  MQ     PD+ATMV ++PACSHLAALQHG C H   I+ G   +TSICN LIDMY+KCG+I+  RQVFD+M  RDI+SWN MI GYGIHGLG  A + F  M   G +PDDVTFI L++ACSHSGLVTEGKHWF+ M+  + I PRMEHYICMVDLL R GFL EA+ FIQ MP +ADVRVW ALL ACR+H NI+LG++VS+ IQ  G EGTGN VLLSNI+SA GR+D+AA VRI QK +G KKSPGCSW+EING +H FVGGDQSHP S  I+ +L+ +L+D+K+LGY A+ SFVLQD+EEEEKE+ LLYHSEKLAIA+ +LSL   K I VTKNLRVCGDCH AIK +TL+  R IIVRD  RFHHFK+G C+C DFW
Sbjct:    7 HLRPFSTAAVRLRRPPSGSISHE--------VKDNKEWQQELEQ-HIARGQLALARQVFDRIPAPDARAYNALIRAYSWRGPFHAAIDLYRSMLYFRVPPNKYTFPFVLKACSALADLCAGRTIHAHAAAVGLHTDLFVSTALIDLYIRCARFGPAANVFAKMPMRDVVAWNAMLAGYANHGMYHHAIAHLLDMQDRGGLRPNASTLVSLLPLLAQHGALFQGTSVHAYCLRAYLDQNEEQVLIGTALLDMYAKCKHLVYACRVFHGMTVRNEVTWSALIGGFVLCDRMTEAFNLFKDMLVEGMCFLSATSVASALRVCASLADLRMGTQLHALLAKSGIHADLTAGNSLLSMYAKAGLINEATMLFDEIAIKDTISYGALLSGYVQNGKAEEAFLVFKKMQACNVQPDIATMVSLIPACSHLAALQHGRCSHGSVIIRGLALETSICNSLIDMYAKCGRIDLSRQVFDKMPARDIVSWNTMIAGYGIHGLGKEATTLFLSMKNQGFEPDDVTFICLIAACSHSGLVTEGKHWFDTMTHKYGILPRMEHYICMVDLLARGGFLDEAYQFIQSMPLKADVRVWGALLGACRIHKNIDLGKQVSRMIQKLGPEGTGNFVLLSNIFSAAGRFDEAAEVRIIQKVKGFKKSPGCSWIEINGSLHAFVGGDQSHPCSPDIYHELDNILIDIKKLGYQADTSFVLQDLEEEEKEKALLYHSEKLAIAFGVLSLNEDKTIFVTKNLRVCGDCHTAIKYMTLVRNRTIIVRDANRFHHFKNGQCSCGDFW 779          

Query:  307 KVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGV-KPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGE----VVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            ++ H  + C  + LA  +FD+IP P +  +N LIRAY+  GP   A+ LY  L +  + +P  YT+PFVLKACS L  L + R +H HA   GL +D++V TAL+D+YAKC     A TVFR M  +DVVAWNAM+AG++LHG Y DTI  L+ MQ    +PNAST+VA+LP +AQ  ALSQG+A+H +S+R     +    V++GT LLDMY+KC  + YA R+F+A+ V+NEV WSA++G +V+C  M EA +LF +M+ +     +P ++ S LRAC  L+DL  G+++H    KSG   +   GN++LSMYAK G+ID A   FD+M  KDTVSYSA++SG VQNG A EA  +F  MQ     PD+ATMV ++PACSHLAALQHG CGH   IV G  ++TSICN LIDMY+KCG+I+  RQ+FD M  RDI+SWN MI GYGIHGLG  A + F  M     +PDDVTFI L+SACSHSGLVTEGK WF+ M+  + ITPRMEHYI MVDLL R GFL EA+ FIQ MP +ADVRVW ALL ACRVH NI+LG++VS  IQ  G EGTGN VLLSNI+SA GR+D+AA VRI QK QG KKSPGCSW+EING +H F+GGD+SH QS++I+++L+ +LVD+ +LGY A+ SFVLQDVEEEEKE+ LLYHSEKLAIA+ +L+L   K I VTKNLRVCGDCH  IK +TL+ KR IIVRD  RFHHFK+G C+C DFW
Sbjct:   68 QIDHNRMICGDLSLARHLFDQIPAPGIHDYNALIRAYSLRGP-ALALRLYRSLRRRRLPQPNNYTFPFVLKACSALLDLRSARAVHCHAARAGLHADLFVSTALVDVYAKCASFRHAATVFRRMPARDVVAWNAMLAGYALHGKYSDTIACLLLMQD-DHAPNASTLVALLPLLAQHGALSQGRAVHAYSVRACSLHDHKDGVLVGTALLDMYAKCGHLVYASRVFEAMAVRNEVTWSALVGGFVLCGRMLEAFSLFKDMLAQGLCFLSPTSVASALRACANLSDLCLGKQLHALLAKSGLHTDLTAGNSLLSMYAKAGLIDQATTLFDQMVVKDTVSYSALVSGYVQNGKADEAFRVFRKMQACNVQPDVATMVSLIPACSHLAALQHGKCGHGSVIVRGIASETSICNALIDMYAKCGRIDLSRQIFDVMPARDIVSWNTMIAGYGIHGLGKEATALFLDMKHQACEPDDVTFICLISACSHSGLVTEGKRWFHMMAHKYGITPRMEHYIGMVDLLARGGFLDEAYQFIQGMPLKADVRVWGALLGACRVHKNIDLGKQVSSMIQQLGPEGTGNFVLLSNIFSAAGRFDEAAEVRIIQKEQGFKKSPGCSWIEINGSLHAFIGGDRSHAQSSEIYQELDNILVDINKLGYRADTSFVLQDVEEEEKEKALLYHSEKLAIAFGVLTLSEDKTIFVTKNLRVCGDCHTVIKYMTLVRKRAIIVRDANRFHHFKNGQCSCGDFW 808          

Query:  226 SLPQAKKIHQHLLKNTTRL--KDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSG---VKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRR-VHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGC 1329
            +L Q + +H + ++  +    KD   +   +  +Y  C  +  ASRVF+ +   + + W+ L+  +   G    A  L+ D+L  G   + PT  +    L+AC+ L  L  G+++H      GL +D+    +L+ +YAK G + +A T+F  M+ KD V+++A+++G+  +G  D+  ++  +MQ     P+ +T+V+++P  +   AL  GK  HG  + R ++ E  +   L+DMY+KC  I  +R+IFD +  ++ V W+ MI  Y I    +EA ALF +M   +   P  VT   ++ AC+    ++ G+R  H  A K G          ++ + A+ G +D+A +F   M  K D   + A++  C
Sbjct:  244 ALSQGRAVHAYSVRACSLHDHKDGVLVGTALLDMYAKCGHLVYASRVFEAMAVRNEVTWSALVGGFVLCGRMLEAFSLFKDMLAQGLCFLSPT--SVASALRACANLSDLCLGKQLHALLAKSGLHTDLTAGNSLLSMYAKAGLIDQATTLFDQMVVKDTVSYSALVSGYVQNGKADEAFRVFRKMQACNVQPDVATMVSLIPACSHLAALQHGKCGHGSVIVRGIASETSICNALIDMYAKCGRIDLSRQIFDVMPARDIVSWNTMIAGYGIHGLGKEATALFLDM-KHQACEPDDVTFICLISACSHSGLVTEGKRWFHMMAHKYGITPRMEHYIGMVDLLARGGFLDEAYQFIQGMPLKADVRVWGALLGAC 615          

Query:  292 SFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERA--IHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLV--QMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR----------SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            S LL+   H  I    +  A  +FD+IP P V  +N LIRAY+ + P   A  +HLY  +L+  V P  YT+PF LKACS L     GR IH+HA   GL +D++V TAL+D+Y KC  L +A  +F  M  +D+VAWNAM+AG++ HG+Y   +  L+  QMQ     PNAST+VA+LP +AQ  AL+QG ++H + +R            L+  V+LGT LLDMY+KC  + YARR+FDA+  +NEV WSA+IG +V+C  M +A  LF  M+ +     +P ++ S LRAC  L  L  G ++H    KSG   +   GN++LSMYAK G+ID A+  FD+M  KDTVSYSA++SG VQNG A+EA L+F  MQ    +PD ATMV ++PACSHLAALQHG C H   I+ G  ++TSICN LIDMY+KCG+I+  RQVF+ M +RDI+SWN MI GYGIHGLG  A + F  M   G  PD VTFI LLSACSHSGLV EGKHWF+ M   + +TPRMEHYICMVDLL R GFL EA+ FIQ MP  ADVRVW ALL ACRV+ NI+LG++VS+ IQ  G EGTGN VLLSNIYSA GR+D+AA VRI QK QG KKSPGCSW+EING +H FVGGDQSHPQS +I+ +L+ +LV +K+LGY  + SFVLQD+EEEEKE+ L+ HSEKLAIAY ILSL   K I VTKNLRVCGDCH  IK I+L+ +R IIVRD  RFHHFK+G C+C DFW
Sbjct:   59 SLLLQLQDH--IASGHLSRAHHLFDQIPSPDVRTYNDLIRAYSSSSPTAAADGLHLYRRMLRHRVAPNNYTFPFALKACSALADHHCGRAIHRHAIHAGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGACRVYKNIDLGKKVSRMIQELGPEGTGNFVLLSNIYSAAGRFDEAAEVRIIQKVQGFKKSPGCSWIEINGSLHAFVGGDQSHPQSPEIYRELDNILVGIKKLGYQPDTSFVLQDLEEEEKEKALICHSEKLAIAYGILSLSEDKTIFVTKNLRVCGDCHTVIKHISLVKRRAIIVRDANRFHHFKNGQCSCGDFW 813          

Query:  226 SLPQAKKIHQHLLK--------NTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSG---VKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTI--LSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGC 1329
            +L Q   +H + ++        + ++L D   L   +  +Y  C  +  A RVFD +P  + + W+ LI  +       +A  L+  +L  G   + PT  +    L+AC+ L  L  G ++H      G+ +D+    +L+ +YAK G + +A  +F  M  KD V+++A+++G+  +G  ++   +  +MQ     P+A+T+V+++P  +   AL  G+  HG  + R L+ E  +   L+DMY+KC  I  +R++F+ +  ++ V W+ MI  Y I    +EA ALF EM       P  VT   +L AC+    +  G+    + +  G+ L   + + I  + + ++ G +D+A  F   M  + D   + A++  C
Sbjct:  243 ALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPT--SIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEM-NNLGFPPDGVTFICLLSACSHSGLVIEGKH-WFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGAC 620          

Query:  292 SFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERA--IHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLV--QMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGE----------VVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            S LL+   H  I    +  A  +FD+IP P V  +N LIRAY+ + P   A  +HLY  +L+  V P  YT+PF LKACS L     GR IH+HA   GL +D++V TAL+D+Y KC  L +A  +F  M  +D+VAWNAM+AG++ HG+Y   +  L+  QMQ     PNAST+VA+LP +AQ  AL+QG ++H + +R  L             V+LGT LLDMY+KC  + YARR+FDA+  +NEV WSA+IG +V+C  M +A  LF  M+ +     +P ++ S LRAC  L  L  G ++H    KSG   +   GN++LSMYAK G+ID A+  FD+M  KDTVSYSA++SG VQNG A+EA L+F  MQ    +PD ATMV ++PACSHLAALQHG C H   I+ G  ++TSICN LIDMY+KCG+I+  RQVF+ M +RDI+SWN MI GYGIHGLG  A + F  M   G  PD VTFI LLSACSHSGLV EGKHWF+ M   + +TPRMEHYICMVDLL R GFL EA+ FIQ MP  ADVRVW ALL ACRV+ NI+LG++VS+ IQ  G EGTGN VLLSNIYSA GR+D+AA VRI QK QG KKSPGCSW+EING +H FVGGDQSHPQS +I+ +L+ +LV +K+LGY  + SFVLQD+EEEEKE+ L+ HSEKLAIAY ILSL   K I VTKNLRVCGDCH  IK I+L+ +R IIVRD  RFHHFK+G C+C DFW
Sbjct:   59 SLLLQLQDH--IASGHLSRAHHLFDQIPSPDVRTYNDLIRAYSSSSPTAAADGLHLYRRMLRHRVAPNNYTFPFALKACSALADHHCGRAIHRHAIHAGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYRIRACLHSNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMRHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGACRVYKNIDLGKKVSRMIQELGPEGTGNFVLLSNIYSAAGRFDEAAEVRIIQKVQGFKKSPGCSWIEINGSLHAFVGGDQSHPQSPEIYRELDNILVGIKKLGYQPDTSFVLQDLEEEEKEKALICHSEKLAIAYGILSLSEDKTIFVTKNLRVCGDCHTVIKHISLLKRRAIIVRDANRFHHFKNGQCSCGDFW 813          

Query:  226 SLPQAKKIHQHLLK--------NTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSG---VKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTI--LSMYAKCGIIDDAVRFFDKMNSK-DTVSYSAIISGC 1329
            +L Q   +H + ++        + ++L D   L   +  +Y  C  +  A RVFD +P  + + W+ LI  +       +A  L+  +L  G   + PT  +    L+AC+ L  L  G ++H      G+ +D+    +L+ +YAK G + +A  +F  M  KD V+++A+++G+  +G  ++   +  +MQ     P+A+T+V+++P  +   AL  G+  HG  + R L+ E  +   L+DMY+KC  I  +R++F+ +  ++ V W+ MI  Y I    +EA ALF EM       P  VT   +L AC+    +  G+    + ++ G+ L   + + I  + + ++ G +D+A  F   M  + D   + A++  C
Sbjct:  243 ALAQGTSVHAYRIRACLHSNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPT--SIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEM-NNLGFPPDGVTFICLLSACSHSGLVIEGKH-WFHVMRHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGAC 620          

Query:  463 LLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLV--QMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR----------SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHFKDGICNCADFW 2520
            +L+  V P  YT+PF LKACS L     GR IH+HA   GL +D++V TAL+D+Y KC  L +A  +F  M  +D+VAWNAM+AG++ HG+Y   +  L+  QMQ     PNAST+VA+LP +AQ  AL+QG ++H + +R            L+  V+LGT LLDMY+KC  + YARR+FDA+  +NEV WSA+IG +V+C  M +A  LF  M+ +     +P ++ S LRAC  L  L  G ++H    KSG   +   GN++LSMYAK G+ID A+  FD+M  KDTVSYSA++SG VQNG A+EA L+F  MQ    +PD ATMV ++PACSHLAALQHG C H   I+ G  ++TSICN LIDMY+KCG+I+  RQVF+ M +RDI+SWN MI GYGIHGLG  A + F  M   G  PD VTFI LLSACSHSGLV EGKHWF+ M   + +TPRMEHYICMVDLL R GFL EA+ FIQ MP  ADVRVW ALL ACRV+ NI+LG++VS+ IQ  G EGTGN VLLSNIYSA GR+D+AA VRI QK QG KKSPGCSW+EING +H FVGGDQSHPQS +I+ +L+ +LV +K+LGY  + SFVLQD+EEEEKE+ L+ HSEKLAIAY ILSL   K I VTKNLRVCGDCH  IK I+L+ +R IIVRD  RFHHFK+G C+C DFW
Sbjct:    1 MLRHRVAPNNYTFPFALKACSALADHHCGRAIHRHAIHAGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGACRVYKNIDLGKKVSRMIQELGPEGTGNFVLLSNIYSAAGRFDEAAEVRIIQKVQGFKKSPGCSWIEINGSLHAFVGGDQSHPQSPEIYRELDNILVGIKKLGYQPDTSFVLQDLEEEEKEKALICHSEKLAIAYGILSLSEDKTIFVTKNLRVCGDCHTVIKHISLVKRRAIIVRDANRFHHFKNGQCSCGDFW 698          

Query:  241 KKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAI-HLYYDLLQ-SGVKPTKYTYPFVLKACSGLQALEAGREIHQHA----------KALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTS-PNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIV-HGFG----TDTSICNVLIDMYSKCGKINRGRQVFDRMVTR-DIISWNAMI 1623
            + IH+H +     L+   F+   +  +Y+ C  +  A+ +F  +P   ++ WN ++  YA +G +  A+ HL    +Q   ++P   T   +L   +   AL  G  +H +               L   V + TAL+D+YAKCG L  A+ VF  M  ++ V W+A+I GF L         +   M   G    + ++I + L   A  + L  G+ +H    +  +  ++  G  LL MY+K   I  A  +FD + VK+ V +SA++  YV      EA  +F +M     + P   T+ S++ AC+ L  L  GR  H   I  G    T + N ++ MYAKCG ID + + F+ M S+D VS++ +I+G   +G  KEA  +F  M   GF PD  T + +L ACSH   +  G   H + ++ HG+G     +  IC  ++D+ S+ G ++   +    M  R D+  W A++
Sbjct:   30 RAIHRHAIH--AGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKM-QACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGK--HWFHVMGHGYGLTPRMEHYIC--MVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALL 502          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAM-----HGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEV-CWSAMIGA 1020
            C     L   +++H  L K+      T+     +  +Y     +D A  +FDE+     + ++ L+  Y  NG  E A  ++  +    V+P   T   ++ ACS L AL+ GR  H      GLAS+  +C ALID+YAKCG +  ++ VF  M  +D+V+WN MIAG+ +HGL  +   + ++M   G  P+  T + +L   + +  + +GK       HG+ L   +   +     ++D+ S+   +  A     ++ ++ +V  W A++GA
Sbjct:  235 CASLDHLRMGEQLHALLAKSGVHADLTAG--NSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMGHGYGLTPRMEHYIC----MVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGA 504          

Query:  463 LLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLV--QMQKAGTSPNASTIVAVLPTVAQANALSQGKAMHGFSLRR----------SLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIVHGFGTDTSICNVLIDMYSKCGKINRGRQVFDRMVTRDIISWNAMIVGYGIHGLGMAAISQFHHMLAAGIKPDDVTFIGLLSACSHSGLVTEGKHWFNAMSEDFNITPRMEHYICMVDLLGRAGFLAEAHVFIQKMPFEADVRVWSALLAACRVHNNIELGEEVSKKIQGKGLEGTGNLVLLSNIYSAVGRWDDAAYVRIKQKGQGLKKSPGCSWVEINGIIHGFVGGDQSHPQSAQIHEKLEELLVDMKRLGYCAENSFVLQDVEEEEKERILLYHSEKLAIAYAILSLRPGKPILVTKNLRVCGDCHAAIKVITLITKREIIVRDLTRFHHF 2487
            +L+  V P  YT+PF LKACS L     GR IH+HA   GL +D++V TAL+D+Y KC  L +A  +F  M  +D+VAWNAM+AG++ HG+Y   +  L+  QMQ     PNAST+VA+LP +AQ  AL+QG ++H + +R            L+  V+LGT LLDMY+KC  + YARR+FDA+  +NEV WSA+IG +V+C  M +A  LF  M+ +     +P ++ S LRAC  L  L  G ++H    KSG   +   GN++LSMYAK G+ID A+  FD+M  KDTVSYSA++SG VQNG A+EA L+F  MQ    +PD ATMV ++PACSHLAALQHG C H   I+ G  ++TSICN LIDMY+KCG+I+  RQVF+ M +RDI+SWN MI GYGIHGLG  A + F  M   G  PD VTFI LLSACSHSGLV EGKHWF+ M   + +TPRMEHYICMVDLL R GFL EA+ FIQ MP  ADVRVW ALL ACRV+ NI+LG++VS+ IQ  G EGTGN VLLSNIYSA GR+D+AA VRI QK QG KKSPGCSW+EING +H FVGGDQSHPQS +I+ +L+ +LV +K+LGY  + SFVLQD+EEEEKE+ L+ HSEKLAIAY ILSL   K I VTKNLRVCGDCH  IK I+L+ +R IIVRD  RFHHF
Sbjct:    1 MLRHRVAPNNYTFPFALKACSALADHHCGRAIHRHAIHAGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMGHGYGLTPRMEHYICMVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGACRVYKNIDLGKKVSRMIQELGPEGTGNFVLLSNIYSAAGRFDEAAEVRIIQKVQGFKKSPGCSWIEINGSLHAFVGGDQSHPQSPEIYRELDNILVGIKKLGYQPDTSFVLQDLEEEEKEKALICHSEKLAIAYGILSLSEDKTIFVTKNLRVCGDCHTVIKHISLVKRRAIIVRDANRFHHF 687          

Query:  241 KKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAI-HLYYDLLQ-SGVKPTKYTYPFVLKACSGLQALEAGREIHQHA----------KALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTS-PNASTIVAVLPTVAQANALSQGKAMHGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEVCWSAMIGAYVICDSMREAMALFDEMVLRKEINPTPVTLGSILRACTKLTDLSRGRRVHCYAIKSGFDLNTMVGNTILSMYAKCGIIDDAVRFFDKMNSKDTVSYSAIISGCVQNGYAKEALLIFHHMQLSGFDPDLATMVGVLPACSHLAALQHGACGHAYSIV-HGFG----TDTSICNVLIDMYSKCGKINRGRQVFDRMVTR-DIISWNAMI 1623
            + IH+H +     L+   F+   +  +Y+ C  +  A+ +F  +P   ++ WN ++  YA +G +  A+ HL    +Q   ++P   T   +L   +   AL  G  +H +               L   V + TAL+D+YAKCG L  A+ VF  M  ++ V W+A+I GF L         +   M   G    + ++I + L   A  + L  G+ +H    +  +  ++  G  LL MY+K   I  A  +FD + VK+ V +SA++  YV      EA  +F +M     + P   T+ S++ AC+ L  L  GR  H   I  G    T + N ++ MYAKCG ID + + F+ M S+D VS++ +I+G   +G  KEA  +F  M   GF PD  T + +L ACSH   +  G   H + ++ HG+G     +  IC  ++D+ S+ G ++   +    M  R D+  W A++
Sbjct:   30 RAIHRHAIH--AGLQADLFVSTALLDMYVKCACLPDAAHIFATMPARDLVAWNAMLAGYAHHGMYHHAVAHLLSMQMQMHRLRPNASTLVALLPLLAQQGALAQGTSVHAYCIRACLHPNRNSKSKLTDGVLLGTALLDMYAKCGSLLYARRVFDAMPARNEVTWSALIGGFVLCSRMTQAFLLFKAMLAQGLCFLSPTSIASALRACASLDHLRMGEQLHALLAKSGVHADLTAGNSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKM-QACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGK--HWFHVMGHGYGLTPRMEHYIC--MVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALL 502          

Query:  211 CIRSKSLPQAKKIHQHLLKNTTRLKDTSFLLEKVAHLYITCNQVDLASRVFDEIPQPSVILWNLLIRAYAWNGPFERAIHLYYDLLQSGVKPTKYTYPFVLKACSGLQALEAGREIHQHAKALGLASDVYVCTALIDLYAKCGGLAEAQTVFRGMLYKDVVAWNAMIAGFSLHGLYDDTIQMLVQMQKAGTSPNASTIVAVLPTVAQANALSQGKAM-----HGFSLRRSLSGEVVLGTGLLDMYSKCQCIAYARRIFDAIDVKNEV-CWSAMIGA 1020
            C     L   +++H  L K+      T+     +  +Y     +D A  +FDE+     + ++ L+  Y  NG  E A  ++  +    V+P   T   ++ ACS L AL+ GR  H      GLAS+  +C ALID+YAKCG +  ++ VF  M  +D+V+WN MIAG+ +HGL  +   + ++M   G  P+  T + +L   + +  + +GK       HG+ L   +   +     ++D+ S+   +  A     ++ ++ +V  W A++GA
Sbjct:  235 CASLDHLRMGEQLHALLAKSGVHADLTAG--NSLLSMYAKAGLIDQAIALFDEMAVKDTVSYSALVSGYVQNGRAEEAFLVFKKMQACNVEPDAATMVSLIPACSHLAALQHGRCSHGSVIIRGLASETSICNALIDMYAKCGRIDLSRQVFNMMPSRDIVSWNTMIAGYGIHGLGKEATALFLEMNNLGFPPDGVTFICLLSACSHSGLVIEGKHWFHVMGHGYGLTPRMEHYIC----MVDLLSRGGFLDEAYEFIQSMPLRADVRVWVALLGA 504