ppa024936m, ppa024936m (mRNA) Prunus persica

Query:   22 YPF-GFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLN--ISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            +PF G S  C+IRLNC+    I +GEFP+++I P+SI V L+ RCNR + +L  L++  YAPT+RN ILL++C    P+S+C IP   V   F++            Y+E  ++  FL    V    C++LLSSIS       N+S+             GWWL G C CH+ A CT + +P  G QGF CKC +G  GDGY AG GC K S  CNP++Y+SGQCGG +RF VL G  +LMIS++ ICCF+RR    KAR  T+R LSEATG C+IP YPY+ IEKAT+ FSEKQ LGTGAYGTVY+GKLH++WVAIKRIKHR  DSIE+V+NEI+LISSV H NLVRLLGCSIE+GEQILVYEFMANGTL QHLQRERG+GL W +RL           HLHSA+ PPIYHRDIKSSNILLD NF  KLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIIT LK VDF RPQNEVNLAALA DRIG+G L+EIIDP LEPH DAW+L S+HKV ELAFRCLAFHRDMRPSMMEV AELE IKL +W ++SEDN  TA                PL+  + K       + +      S+NS   L KD SPVSV
Sbjct:   43 FPFIGTSSACQIRLNCSTDGDIMVGEFPVRSIFPESILVNLEVRCNRSIKSLDHLFNTNYAPTTRNGILLKHCKS--PASTCTIPTTKVNTHFESIDCGSDNYSISCYSEEHEN-GFLSQANVSKSHCQYLLSSISVDA---FNTSSVVLDVGIVQL---GWWLLGECKCHQEATCTEIQTPVAGQQGFRCKCRDGFDGDGYQAGVGCRKASSGCNPSRYISGQCGGPSRFFVLAGGIALMISISAICCFMRRCLTSKARNSTRRRLSEATGKCSIPIYPYRAIEKATSSFSEKQRLGTGAYGTVYSGKLHNQWVAIKRIKHRDTDSIEEVLNEIKLISSVSHPNLVRLLGCSIEKGEQILVYEFMANGTLSQHLQRERGNGLVWAVRLSIATQTAQAIAHLHSALNPPIYHRDIKSSNILLDHNFIPKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITALKVVDFSRPQNEVNLAALAIDRIGKGRLDEIIDPFLEPHRDAWSLSSLHKVAELAFRCLAFHRDMRPSMMEVAAELEQIKLCKW-ATSEDNMCTASSETSSCSSSSNVSEIPLSMTVEKGGLGSEGLFVLPTKVISMNSLGRL-KDTSPVSV 669          

Query:   16 IHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERG 1152
            +HYPFGFS    I+LNC+    I I  F +Q +T DSI + L ++C R +  +  L+   YA +S+N++L QNC+    SS C IP  +   +                     +  F+ F  V    CKFLL S++    +  N+SA             GWWL+  C C  NA  T +  P G  G  C C  G  GDG+  G GC + +  CN +KY+SG CGG TR  VL+G     ASLM ++ALIC  IRR+S L+ R+  KRL+ EA GN ++P YPYKE+E+ATNGFSEKQ LGTGAYGTV+AGKLH DEWVAIK+I++R NDSIEQVMNEI+LISSV H NLVRLLGC IE GEQILVYEFMANGTL QHLQ+ERG
Sbjct:   46 VHYPFGFSSDSPIKLNCSKEGEIEIQNFKVQNVTTDSIIINLPAQCQREIQKIEPLFGKNYALSSKNSLLFQNCSSS--SSGCVIPTSVFNGQNKLNNCNGKSDNNISCFPLDSESEFMSFANVTGTGCKFLLLSMAV---EWRNNSAVSLELGTAQL---GWWLDHPCHCAPNAKHTNLTVPGGF-GCRCSCKEGFDGDGFKDGDGCQEVTD-CNASKYMSGTCGGTTRVAVLVGGVIVGASLMSTVALICYCIRRRSYLRRRMSAKRLICEAAGNSSVPLYPYKEVERATNGFSEKQRLGTGAYGTVFAGKLHNDEWVAIKKIRNRDNDSIEQVMNEIKLISSVNHPNLVRLLGCCIENGEQILVYEFMANGTLSQHLQKERG 420          

Query: 1474 KAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSVH 1923
            K VDF RP +EVNLAALA DRIGRGC++EIIDP LEP  DAWTL S+HKV ELAFRCLAFHRDMRPSMMEV  ELE ++LS W +  E+N   A                  +++ S S R  + +       L S E + KD+SPVSVH
Sbjct:  421 KVVDFSRPHSEVNLAALAIDRIGRGCVDEIIDPFLEPQRDAWTLCSIHKVAELAFRCLAFHRDMRPSMMEVADELEHVRLSGW-APMEENICVAS-----------------SVASSWSRR--LFVPHRPTDCLASMEEI-KDSSPVSVH 549          

Query:  526 CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFI--------RRQSKLKARLCTKR--LLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEW-VAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG---LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            C    N T    P       C C +GL  D    G  C +     +P       CG   +  ++ G ++ I  ALI   I        RR  + + RL  +R  +L+   G      +  KEI++ATN FS  + LG G YG VY G L D   VAIK  K       +QV+NE+ ++  V H++LVRLLGC +E  + I+VYEF+ NGTL +HLQ +R  G   L+W  RL           +LHS+  PPIYHRD+KSSNILLD    AK+ADFGLSRL   + SH+ST  QGT GYLDP+Y++N+ L+DKSDVYSFGVVL+E++T  KA+DF RP ++VNLA      +    L + IDPLL+    +  L ++  +G LA  CL   R  RPSM EVT E+  I
Sbjct:  218 CTDGMNSTCGPDPATAGVSRCFCKSGLWWDP--VGGLCAQNVTCQDP-----DGCGSTNKTPLIAGLTVGIGAALIAAVIAILVYRRHRRIKEAQDRLAREREEILNANGGGKFAKNFTGKEIKRATNSFSHDRLLGAGGYGEVYKGILDDGTIVAIKCAKLGNAKGTDQVLNEVGILCQVNHRSLVRLLGCCVELEQPIMVYEFIPNGTLLEHLQGQRPGGRGSLTWSHRLRIAHDTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKMNAKVADFGLSRLAHTDMSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNRPADDVNLAVYVQRTVEEERLMDAIDPLLKEQASSLELETMKAMGFLAVGCLEERRQNRPSMKEVTEEIGYI 618          

Query:  670 KYLSGQCGGKTRFIVLIGASLM---ISLALICCFIRRQSK--------LKARLCT----KRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSED 1740
            K+     G   R  + +G  +    I++ +IC FI  QS         L    C+    K  L        IP +PY E+E+ATN F   + +G G +GTVY G+L D   VA+KR+    +  +EQ MNE+++++ +RH+NLV L GC+     E +LVYEF+ NGT+  HL  +R D   L+WPIRL           +LH++    + HRD+K+ NILLD +F  K+ADFGLSRL   + +H+STAPQGTPGY+DP+YHQ + L+DKSDVYSFGVVL+E+I+ L AVD  R ++E+NL+  A ++I +   +E+IDP L    D         V ELAFRCL   ++MRPSM EV   L+ I+  +  S + D
Sbjct:  250 KFRCAHTGNDKRLKLALGLGISAGSITILIICFFIIWQSHKRKYAPTFLSRNTCSDPSSKSELEITGAYFGIPIFPYTELEEATNYFDPDREIGDGGFGTVYHGQLRDGREVAVKRLYENNHRRVEQFMNEVQILTRLRHRNLVSLYGCTSRHSRELLLVYEFIPNGTVADHLHGDRADSGLLTWPIRLSIAIETATALCYLHAS---DVVHRDVKTKNILLDDSFCVKVADFGLSRLFPTDVTHVSTAPQGTPGYVDPEYHQCYQLTDKSDVYSFGVVLIELISSLPAVDINRHRHEINLSNYAINKIQKCAFHELIDPRLGFDSDLAVNRMTTLVAELAFRCLQPDKEMRPSMDEVLEILKEIESDKHESENMD 622          

Query:  631 SGCW----KGSQVCNPAKYLSGQC----GGKTRFIVLIGASLM---ISLALICCFIRRQSKLK-ARLCTKRLLS---------EATGNC-NIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSR 1719
            S CW    +G Q C   +    QC    G   R  + +G+ +    I++ +IC  IR++ K K A     R  S         E TG    IP +PY E+E+AT  F   + +G G +GTVY G+L D   VA+KR+       +EQ MNE+++++ +RH+NLV L GC+     E +LVYEF+ NGT+  HL   R D   L+WPIRL           +LH++    + HRD+K+ NILLD +F  K+ADFGLSRL   + +H+STAPQGTPGY+DP+YH    L+DKSDVYSFGVVL+E+I+ L AVDF R ++E+NL+  A ++I +   +E+IDP L  + D         V ELAFRCL   ++MRPSM EV   L+ I+ +R
Sbjct:  913 SHCWNCLNRGGQ-CQDDEKGKFQCAHVKGNDNRLKLALGSGISAGGITILIICFIIRQRHKRKYASTFLSRNTSSDPSSQPGLETTGTYFGIPIFPYSELEEATYHFVPDREIGDGGFGTVYHGQLRDGREVAVKRLYENNYRRVEQFMNEVQILTRLRHRNLVSLYGCTSRHSRELLLVYEFIPNGTVADHLHGNRADSGLLTWPIRLSIAIETASALCYLHAS---DVVHRDVKTKNILLDNSFCVKVADFGLSRLFPTDVTHVSTAPQGTPGYVDPEYHLCHQLTDKSDVYSFGVVLIELISSLPAVDFSRLKHEINLSNYAINKIQKCAFHELIDPHLGFNSDLAVNRMTTLVAELAFRCLQPDKEMRPSMDEVLEILKEIESNR 1297          

Query:  736 ISLALICCFI---RRQSKLKARLCTKRLLSEATGN---------CNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            I   +IC FI   RR+ K  +   ++   S+ +             I  +PY E+E+ATN F   + +G G +G+VY G+L D   VA+KR+       +EQ MNE+++++ +RH+NLV L GC+     E +LVYEF+ NGT+  HL  +R D   L+WPIRL           +LH++    + HRD+K+SNILLD +F  K+ADFGLSRL   + +H+STAPQGTPGY+DP+YHQ + L+DKSDVYSFGVVL+E+I+ L AVD  R ++E+NL+  A ++I +   +E++DP L    D         V ELAFRCL   ++MRPSM EV   LE++K
Sbjct:  238 IPFLIICFFIIRQRRKGKYASTFLSRNTSSDPSSQPGLETAGAYFGIAIFPYTELEEATNYFDPDREIGDGGFGSVYHGQLRDGREVAVKRLYENNYRRVEQFMNEVQILTRLRHRNLVSLYGCTSRHSRELLLVYEFIPNGTVADHLHGDRADSGLLTWPIRLSIAIETATALCYLHAS---DVVHRDVKTSNILLDNSFCVKVADFGLSRLFPTDVTHVSTAPQGTPGYVDPEYHQCYQLTDKSDVYSFGVVLIELISSLPAVDISRHRHEINLSNYAINKIQKCAFHELMDPHLGFDSDLAVNRMTTLVAELAFRCLQPDKEMRPSMDEV---LEILK 572          

Query:  670 KYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKLKARLCTKRLLS---------EATGNCN-IPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGD--GLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEV 1686
            K + G C G          +L+IS      ++RR  K        R +S         E+ G+ + +  + Y+E+E+ATN F   + LG G +GTVY GKL D   VA+KR+       +EQ MNE+ ++  +RH+NLV L GC+     E +LVYE++ NGT+  HL  E+     L+WP R+           +LH++    I HRD+K++NILLD NF  K+ADFGLSRL   + +H+STAPQGTPGY+DP YHQ + L+ KSDVYSFGVVL+E+I+ + AVD  R ++E+NL+ +A ++I    L+E++D  L    D      +  V ELAF+CL   ++MRP+M EV
Sbjct:  575 KVIIGVCAGL--------GTLLISSIFFLMYLRRYKKRYPPPLFSRNISSDPSSKTIFESQGSLHGVHIFTYEELEEATNNFDSSKELGDGGFGTVYHGKLRDGRVVAVKRLYENNYKRVEQFMNEVEILQLLRHRNLVSLYGCTSRHSRELLLVYEYVPNGTVADHLHGEQAKPGSLTWPTRMKIAIETASALKYLHAS---DIIHRDVKTNNILLDSNFSVKVADFGLSRLFPTDVTHVSTAPQGTPGYVDPDYHQCYQLTSKSDVYSFGVVLIELISSMPAVDITRHRHEINLSNMAINKIQNHALHELVDRSLGFDSDQNIRRMIMAVAELAFQCLQNEKEMRPAMDEV 916          

Query:  712 VLIGASLMISLALICCFIRRQSKLKAR--LCTKR--LLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWV-AIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQ---RERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGM---AESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            V+    +++ + ++ C  R+  K +A+  L  KR  +L+          +  KEI++ATN FS+   +G+G +  V+ G L D  V A+KR K       +QV+NE+R++  V H+ LVRLLGC +E  + I++YE++ NGTL  HL      +   L+W  RL           +LHS+  PPIYHRD+KSSNILLD    AK++DFGLSRL +   A +SHI+T  QGT GYLDP+Y++NF L+DKSDVYSFGVVL+E++T  KA+DF R + +VNL       +    L ++IDP+L+       + SV  +G LA  CL   R  RPSM E   E+E I
Sbjct:  285 VVAAILILVPVGILVCRHRQNLKREAQGSLIKKREDMLNANNSGKMAKIFSGKEIKRATNNFSKDNFIGSGGFSEVFKGILDDGTVTAVKRAKLGNTKGTDQVLNEVRILCQVNHRCLVRLLGCCVELEQPIMIYEYIPNGTLFDHLHGHHSRKWPALTWRRRLSIALQTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKLDAKVSDFGLSRLAVVSEANASHITTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVLYIKKIMKEEKLMDVIDPVLKDGASKVDMESVKALGLLAAACLDERRQSRPSMKEAAEEIEYI 627          

Query:  526 CHKNANCT--TVVSPNGTQGFT-CKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICC-----FIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLL-SVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            C    +CT  +  SP G +G   C CN G   D  +A   C K  +    A  L    G  + F      SL +++A +       F  ++  +KAR   + +L  + G  +   +  KE++KATNGFS+ + LG+G +G VY                                  V H+NLV+LLGC +E  + +++Y ++ NGTL +HL  +R   L W  RL           +LHSA   PIYHRD+KS+NILLD +F AK+ADFGLSRL     SH+ST  QGT GYLDP+Y++N+ L+DKSDVYS+G+V++E++T  KA+DF R  +++NLA   + R   G +  ++D  L  H  +  ++ S+    ELA  CL   +  RPSM  V  EL+ I
Sbjct:  229 CKTQLDCTRDSKCSPAGGKGLLRCLCNRGYYWD--LARGTCLKKEKNSKLAISLKVSIGVVSFF------SLAVAIAAVTVRRSGKFSNQEKLVKAR---EEMLKSSMGGKSARMFSLKEVKKATNGFSKDRVLGSGGFGEVY---------------------------------KVNHKNLVKLLGCCVEAEQPLMIYNYIPNGTLHEHLHGKRSTFLKWDTRLRIALQTAEALAYLHSAAHTPIYHRDVKSTNILLDEDFNAKVADFGLSRLAEPGLSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSYGIVMLELLTSQKAIDFSREPDDINLAIYVSQRASDGAVMGVVDQRLLGHNPSVEVITSIRLFSELALACLREKKGERPSMKAVVQELQRI 587          

Query:  850 PYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEW-VAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELE 1701
            P  EI+ ATN FS K  +G G +G VY G L +   VA+KR +      + +   EI ++S +RH++LV L+G   ER E ILVYEFM NGTL  HL       LSW  RL           +LH+  +  I HRD+KS+NILLD NF AK+ADFGLSR G+   +H+STA +GT GYLDP+Y +   L++KSDVYSFGVVL+E++    A++   P+ +VNLA     R   G L  +IDPLL   ++   L S+ K GE A +CL      RP+M +V  +LE
Sbjct:  487 PLAEIQSATNNFSSKLLVGKGGFGKVYQGTLRNGMKVAVKRSQPGHGQGLPEFQTEILVLSKIRHRHLVSLIGYCDERNEMILVYEFMQNGTLRNHLYDSDFPCLSWKQRLEICIGAARGLHYLHTGSEGGIIHRDVKSTNILLDENFVAKVADFGLSRSGLLHQTHVSTAVKGTIGYLDPEYFRTQKLTEKSDVYSFGVVLLEVLCARPAINPLLPREQVNLAEWVMVRQKEGFLEHVIDPLLVGKVN---LNSLRKFGETAEKCLQEDGADRPTMGDVVWDLE 768          

Query:  712 VLIGASLMISLALICCF-------IRRQS--KLKARLCTKR---LLSEATGNCNIPFYPYK-----EIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGD-GLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLS 1716
            +++G S+   L L+  F       +R+Q   ++K R   +    LL +   +  I F   K     E+EKAT+ F++ + LG G  GTVY G L+D   VA+K+ K    + +E  +NEI ++S + H+N+V +LGC +E    +LVYEF++NGTL Q +  +  +  LSW +RL           +LHSA   PIYHRDIKS+NILLD  +KAK++DFG SR    + +H++T  QGT GYLDP+Y Q+   ++KSDVYSFGVVLVE++TG K +   R   E +LA      +    L +I+D  +        +++  K   LA RCL  +   RP+M EVT E++ I++S
Sbjct:  193 LILGCSISGGLLLLLIFSFGLYKVVRKQLDIRVKKRFFKRNGGLLLQQQISSDKIAFEKTKIFTSDELEKATDNFNKNRILGQGGQGTVYKGMLNDGRIVAVKKSKIVDENQLEHFINEIVILSQINHRNVVGILGCCLETEVPLLVYEFISNGTLFQLIHDQNSEFPLSWEMRLRIALEVSGALSYLHSACSIPIYHRDIKSTNILLDDKYKAKVSDFGTSRSISIDQTHLTTIVQGTFGYLDPEYFQSSQFTEKSDVYSFGVVLVELLTGQKPISSTRSPEEKSLATHFILSLQESRLFDILDARVVKEGRKEDIMTFAK---LAGRCLNLNGRKRPTMKEVTTEIDNIRVS 543          

Query:   22 YPF-GFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLN--ISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            +PF G S  C+IRLNC+    I +GEFP+++I P+SI V L+ RCNR + +L  L++  YAPT+RN ILL++C    P+S+C IP   V   F++            Y+E  ++  FL    V    C++LLSSIS       N+S+             GWWL G C CH+ A CT + +P  G QGF CKC +G  GDGY AG GC K S  CNP++Y+SGQCGG +RF VL G  +LMIS++ ICCF+RR    KAR  T+R LSEATG C+IP YPY+ IEKAT+ FSEKQ LGTGAYGTVY+GKLH++WVAIKRIKHR  DSIE+V+NEI+LISSV H NLVRLLGCSIE+GEQILVYEFMANGTL QHLQRERG+GL W +RL           HLHSA+ PPIYHRDIKSSNILLD NF  KLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIIT LK VDF RPQNEVNLAALA DRIG+G L+EIIDP LEPH DAW+L S+HKV ELAFRCLAFHRDMRPSMMEV AELE IKL +W ++SEDN  TA                PL+  + K       + +      S+NS   L KD SPVSV
Sbjct:   43 FPFIGTSSACQIRLNCSTDGDIMVGEFPVRSIFPESILVNLEVRCNRSIKSLDHLFNTNYAPTTRNGILLKHCKS--PASTCTIPTTKVNTHFESIDCGSDNYSISCYSEEHEN-GFLSQANVSKSHCQYLLSSISVDA---FNTSSVVLDVGIVQL---GWWLLGECKCHQEATCTEIQTPVAGQQGFRCKCRDGFDGDGYQAGVGCRKASSGCNPSRYISGQCGGPSRFFVLAGGIALMISISAICCFMRRCLTSKARNSTRRRLSEATGKCSIPIYPYRAIEKATSSFSEKQRLGTGAYGTVYSGKLHNQWVAIKRIKHRDTDSIEEVLNEIKLISSVSHPNLVRLLGCSIEKGEQILVYEFMANGTLSQHLQRERGNGLVWAVRLSIATQTAQAIAHLHSALNPPIYHRDIKSSNILLDHNFIPKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITALKVVDFSRPQNEVNLAALAIDRIGKGRLDEIIDPFLEPHRDAWSLSSLHKVAELAFRCLAFHRDMRPSMMEVAAELEQIKLCKW-ATSEDNMCTASSETSSCSSSSNVSEIPLSMTVEKGGLGSEGLFVLPTKVISMNSLGRL-KDTSPVSV 669          

Query:    4 GTDPIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQV-------CNPAKYLSGQCGGKTRFIVLIG---ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSE---RSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            GT+ + YPFGFS  C+I LNC+PH  + I EFP+Q +  +SI++ L+ +CNRPL  L  L++  YAP S NAILL NCT     S C IP+I VQ  F++              E   +  F D+       C++ LSSISA       S                WWL+G C C K+A CT V SP G+ GF C+C +GL+GDGY+AG GC KGS +       CNPAKYLSGQCGG +   VL+G   A + +SL L CC +RR S  KA+   K  LSEA  + NIP YPYKEIEKATN FSEKQ +GTGAYGTVYAGKL+ D WVAIKRIKH   D+IEQVMNEI+LISSV H NLVRLLGCSIE GEQILVYEFM NGTLCQHLQRERGDGL WP+RL           HLHSA+ PPIYHRDIKSSNILLD +F++K+ADFGLSR GM E SHIST PQGTPGYLDPQYH NFHLSDKSDVYSFGVVLVEIIT  K VDF RPQNEVNLAALATDRIGRG L+EIIDP L+ H DAWT  SVHKV E+AFRCLAFH+DMRPSMMEV AELE I LSRW SS E N                   KPLN +  ++E   R + +LQ+    S  STE     NSPVSV
Sbjct:   34 GTNHLPYPFGFSADCDIHLNCSPHGEMLINEFPVQIVGQNSIKIILEPKCNRPLEALDNLFTKNYAPKSTNAILLHNCTSAV--SPCNIPSINVQTHFESLKCSNNSSLSCFSKEVTAN-GFFDYNMANISQCQYFLSSISAE------SFTGSGVSLEIQMMELWWWLQGDCRCSKDAICTQVESPAGS-GFRCQCRDGLIGDGYLAGVGCRKGSFLDVKASAGCNPAKYLSGQCGGGSGAAVLLGGVVAGVGVSLGLFCCLVRRNSASKAKSFRKLHLSEAA-DINIPIYPYKEIEKATNSFSEKQRIGTGAYGTVYAGKLNSDSWVAIKRIKHGDMDNIEQVMNEIKLISSVSHPNLVRLLGCSIENGEQILVYEFMPNGTLCQHLQRERGDGLDWPVRLAIAADTAKAIAHLHSAMDPPIYHRDIKSSNILLDYHFRSKVADFGLSRHGMTEISHISTVPQGTPGYLDPQYHLNFHLSDKSDVYSFGVVLVEIITAKKVVDFSRPQNEVNLAALATDRIGRGRLDEIIDPFLDLHSDAWTFSSVHKVAEVAFRCLAFHKDMRPSMMEVAAELEQILLSRWASSEETNC-AISLDFSPCSSSSNVSDKPLNSTVKKTEIERRGLFVLQTQT--SKKSTER-ANHNSPVSV 671          

Query:    4 GTDPIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG---ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSE---RSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            GT  + YPFGFS  C+I LNC+ +  + I +FP+Q +  D+I++ L+ RC RP+  L  L +  YAP S NAILL NCT G   S C IP+I V+  F++            +++      F D+       CK+LLSSISA       S                WWL+G C C K+A CT V SP G+ GF C+C +GL+GDGY+AG GC K +  CNPAKYLSGQCG   R  VL+G   A++ + L L CC  RR S  KA+   K   +EA  + +IP YPYKEIEKATN FSEKQ +GTGAYGTVYAGKL  D WVAIKRIKHR  DSIEQV+NEI+LISSV H NLVRLLGCSIE  EQILVYEFM NGTLCQHLQR RGDGL WP+RL           HLHSAI PPIYHRDIKSSNILLD +FK+K+ADFGLSR GM + SHIST PQGTPGYLDPQYHQNFHLSDK+DVYSFGVVL+EIIT  K +DF RPQ+EVNLA+LA D+IGRG L+EIIDP L+ H DAWT  SVHKV ELAFRCLAFH+D+RPSMMEV AELE I L+RWP S E N  T                K LN++  ++E   R +++LQ+ A  S  STE     NSP+SV
Sbjct:   34 GTSHLPYPFGFSANCDIHLNCSLNGEMLINDFPVQIVGQDTIKINLEPRCYRPVEALYNLSTKNYAPKSTNAILLNNCTSG--FSPCNIPSISVRTHFESLNCSNNSSVSC-FSKADTANGFFDYNMANISQCKYLLSSISAE------SFTGSGVSLETQMMELWWWLQGDCQCSKDAICTKVESPAGS-GFRCQCRDGLIGDGYLAGVGCRKAAG-CNPAKYLSGQCGAGARPAVLLGGIVAAVGVGLGLFCCLTRRNSISKAKSFRKLHRAEAA-DISIPIYPYKEIEKATNSFSEKQRIGTGAYGTVYAGKLSSDSWVAIKRIKHRDVDSIEQVINEIKLISSVSHPNLVRLLGCSIENDEQILVYEFMPNGTLCQHLQRVRGDGLDWPVRLAIATETAKAIAHLHSAIDPPIYHRDIKSSNILLDFDFKSKVADFGLSRHGMTDMSHISTVPQGTPGYLDPQYHQNFHLSDKTDVYSFGVVLIEIITAKKVLDFSRPQDEVNLASLAIDKIGRGLLDEIIDPFLDLHNDAWTFSSVHKVAELAFRCLAFHKDIRPSMMEVAAELEQIMLTRWPPSEEINC-TTSLDFSQCSSSSHVSEKALNLTVKKTEIERRGLLVLQTQA--SRKSTER-TDHNSPMSV 663          

Query:   16 IHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTC-----GCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQS-KLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPL---NISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            + YPFGFS GCEI+LNC   TG I IGEF +Q ITP+ I V+L ++CNR L  +  L+   YAP  RN +LLQNCT  +  SSC IP      +               Y+     +  L +  +    CKFL SS +         S               WWL+G+C      C K+ANCT +   +G  GF C C  G  GDG+  G GC +    CN +KY++GQCGG TR  VL+G     ASLM  LALI  F+R++S  L+ RL  KRLL EA GN ++PFYPY+EIEKATNGFSEKQ LG GAYGTVYAGKLH +EWVAIK+I+HR  DSI+QVMNEI+L+SSV H NLVRLLGC IE GE ILVYEFM +GTLCQHLQRERG GL W IRL           +LHSA+ PPIYHRDIKSSNILLD N+K+K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVLVEIITGLK VDF RP +EVNLAALA DRIGRGC++EIIDP L+P+ DAWTL S+H V ELAFRCLAFHRDMRP+MMEV  ELE I+LS W      N Y A               + L   +I K+      +L+    A  L S E + KD+SPVSV
Sbjct:   44 VSYPFGFSDGCEIQLNCRQDTGDIGIGEFVVQNITPNGILVSLPAKCNRSLEAISPLFGDHYAPAWRNGLLLQNCT--RTLSSCYIPTSSFANQLHIPSCNPRSDNITCYSRERLGMDVLSYNNLNSAGCKFLFSSFAVG-------SNNPSVSLEFERVELDWWLDGSCKLNRSNCSKHANCTDIKLGDGKGGFRCWCQEGFTGDGFRNGDGC-RSVSGCNASKYINGQCGGTTRVGVLVGGIIAGASLMAGLALIWYFVRQRSTSLRNRLSAKRLLCEAAGNSSVPFYPYREIEKATNGFSEKQRLGIGAYGTVYAGKLHNEEWVAIKKIRHRDTDSIDQVMNEIKLLSSVSHPNLVRLLGCCIEEGEPILVYEFMPHGTLCQHLQRERGKGLPWTIRLTIAAETANAIAYLHSAMNPPIYHRDIKSSNILLDYNYKSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQYFHLSDKSDVYSFGVVLVEIITGLKVVDFSRPHSEVNLAALAIDRIGRGCVDEIIDPYLDPNRDAWTLSSIHNVAELAFRCLAFHRDMRPTMMEVAEELEHIRLSAW----VPNMYMASPAASSCSSPDNGSERSLGVHSIKKAGVVSRRLLVPQRPADCLTSLEEI-KDSSPVSV 679          

Query:  133 VTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXX--YAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGT-CGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-----SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHM--DAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISK---SQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            V+++++CNRP  +L  L+S +YAPTSRN ILL+NCT G P   C IP  LV+  F++              Y E   +  F+D   ++   CK+ +SS++A  P + N S              GWWL+G  C C  +ANCTT+ SP +G  GF C+C +G +GDG++AG+GC K S  CNPAKY+SG+CGG TRFIVLIG      SLM++L  +CCF RR+SKL+    TKR L+EATG  ++P YPYK+IEKATN FSEKQ LGTGAYGTVYAGKL++ EWVAIKRIKHR  DSIEQVMNEI+L+SSV H NLVRLLGCSIE GEQILVYEFM NGTL QHLQ+ERG GL WPIRL           +LHSAI PPIYHRDIKSSNILLD NF++K+ADFGLSRLGM E SHIST PQGTPGY+DPQYHQ+FHLSDKSDVYS GVVLVEIITGLK VDF RP NEVNLA+LA D+IG+G LNEIIDP LEP +  DAWTL S+HKV ELAFRC+AFHRDMRPSM EV +ELE ++LSRW +  ++N  T+               KPL+I+        +  + LQ+G   +L S +     NSPVSV
Sbjct:    3 VSIEAQCNRPFDSLHHLFSHKYAPTSRNVILLENCT-GTPLP-CFIPETLVRTHFESVGCNNASGTGELSCYFENRTN-GFVDRRTLDEIGCKYFMSSLAA--PDIKNISGAPLSLDVNIIQL-GWWLQGDQCLCSDHANCTTLQSPMDGKPGFRCRCRDGFVGDGFLAGTGCRKASS-CNPAKYISGRCGGTTRFIVLIGGFVVGVSLMVTLGSLCCFYRRRSKLRVTNSTKRRLTEATGKNSVPIYPYKDIEKATNSFSEKQRLGTGAYGTVYAGKLYNNEWVAIKRIKHRDTDSIEQVMNEIKLLSSVSHTNLVRLLGCSIEYGEQILVYEFMPNGTLSQHLQKERGSGLPWPIRLTIATETAQAIAYLHSAICPPIYHRDIKSSNILLDYNFRSKVADFGLSRLGMTEISHISTTPQGTPGYVDPQYHQDFHLSDKSDVYSLGVVLVEIITGLKVVDFSRPHNEVNLASLAADKIGKGLLNEIIDPFLEPEVRSDAWTLSSIHKVAELAFRCIAFHRDMRPSMTEVASELEQLRLSRWTTLGDNNCATS-TELSSCSSSSNECEKPLSIATRNFGAKGKGHLKLQTGPI-NLKSLQR-PNSNSPVSV 603          

Query:   16 IHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPL---NISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSVH 1923
            +HYPFGFS    I+LNC+    I I  F +Q +T DSI + L ++C R +  +  L+   YA +S+N++L QNC+    SS C IP  +   +                     +  F+ F  V    CKFLL S++    +  N+SA             GWWL+  C C  NA  T +  P G  G  C C  G  GDG+  G GC + +  CN +KY+SG CGG TR  VL+G     ASLM ++ALIC  IRR+S L+ R+  KRL+ EA GN ++P YPYKE+E+ATNGFSEKQ LGTGAYGTV+AGKLH DEWVAIK+I++R NDSIEQVMNEI+LISSV H NLVRLLGC IE GEQILVYEFMANGTL QHLQ+ERG GL W  RL           HLHSAI PPI+HRDIKSSNILLD NF +K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEII+ +K VDF RP +EVNLAALA DRIGRGC++EIIDP LEP  DAWTL S+HKV ELAFRCLAFHRDMRPSMMEV  ELE ++LS W +  E+N   A                 L   ++ K+      + +       L S E + KD+SPVSVH
Sbjct:   36 VHYPFGFSSDSPIKLNCSKEGEIEIQNFKVQNVTTDSIIINLPAQCQREIQKIEPLFGKNYALSSKNSLLFQNCSSS--SSGCVIPTSVFNGQNKLNNCNGKSDNNISCFPLDSESEFMSFANVTGTGCKFLLLSMAV---EWRNNSAVSLELGTAQL---GWWLDHPCHCAPNAKHTNLTVPGGF-GCRCSCKEGFDGDGFKDGDGCQEVTD-CNASKYMSGTCGGTTRVAVLVGGVIVGASLMSTVALICYCIRRRSYLRRRMSAKRLICEAAGNSSVPLYPYKEVERATNGFSEKQRLGTGAYGTVFAGKLHNDEWVAIKKIRNRDNDSIEQVMNEIKLISSVNHPNLVRLLGCCIENGEQILVYEFMANGTLSQHLQKERGKGLPWTTRLNIATETANAIAHLHSAITPPIFHRDIKSSNILLDDNFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIISAMKVVDFSRPHSEVNLAALAIDRIGRGCVDEIIDPFLEPQRDAWTLCSIHKVAELAFRCLAFHRDMRPSMMEVADELEHVRLSGW-APMEENICVASSVASSCSSPFNGSEMSLGCMSVRKAGIGSRRLFVPHRPTDCLASMEEI-KDSSPVSVH 668          

Query:   13 PIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVR-FLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGT-CGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLL--EPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTA 1755
            P+ YPFGFS GC IRLNCT      +GEFP++  T DS+ V+++++CNR   +   L+S +YAPTSRN ILL NCT       C IP  LV+  F++                 K    F+D   ++   CK+ +SS+S   P + N S              GWWL+G  C C  +ANCTT+ SP +   GF C+C +G +GDG++ G+GC KG                      +IG SLM++L  +CCF RR+SKL+    TKR L+EATGN ++P YPYK+IEKATN FSEKQ LGTGAYGTVYAGKL+ DEWVAIKRIKHR  DSIEQVMNEI+L+SSV H NLVRLLGCSIE GEQILVYEFM NGT  QHLQ+ERG GL WP+RL           HLHSAI PPIYHRDIKSSNILLD NF++K+ADFGLSRLGM E SHISTAPQGTPGY+DPQYHQ+FHLSDKSDVYS GVVLVEIITG K VDF RP NEVNLA+LA DRIG+G LNEIIDP L  E   DAWTL S+HKV ELAFRCLAFHRDMRPSM EV +ELE + LSRW +  ++N  T+
Sbjct:   48 PVPYPFGFSSGCAIRLNCTAGVAS-VGEFPVKVNT-DSLIVSIEAQCNRSFDSFHHLFSHKYAPTSRNVILLDNCT--ATPLPCSIPETLVRTHFESVGCGNASGTGELSCYFEKITNGFMDQRMLDEIRCKYFMSSLSV--PDIKNISGTAPLSLGVNVIELGWWLQGDRCLCSDHANCTTLQSPVDRKPGFRCRCRDGFVGDGFLVGTGCQKG---------------------FVIGVSLMVTLGSLCCFYRRRSKLRVTKSTKRRLTEATGNNSVPIYPYKDIEKATNSFSEKQRLGTGAYGTVYAGKLYNDEWVAIKRIKHRDTDSIEQVMNEIKLLSSVSHTNLVRLLGCSIEYGEQILVYEFMPNGTRSQHLQKERGSGLPWPVRLTIATETAQAIAHLHSAICPPIYHRDIKSSNILLDYNFRSKVADFGLSRLGMTEISHISTAPQGTPGYVDPQYHQDFHLSDKSDVYSLGVVLVEIITGQKVVDFSRPHNEVNLASLAADRIGKGLLNEIIDPFLEAEARSDAWTLSSIHKVAELAFRCLAFHRDMRPSMTEVASELEQLSLSRWTTMGDNNCATS 607          

Query:   16 IHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQ-LLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALIC-CFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPS 1728
            + YPFGFS GC IRL+CT  TG I IGE+ IQ +T +++ V     C+RP+  L+Q     +  T RN +LL NC    P S C IP+ ++  R +             Y+E   D  +LD++K+++  C  ++SSI        + SSA              W LEG C CH +ANCT V  P   +GF C+C +G +GDG+  G GC K S+ CNP++YLSG+CGG TR  VL+G     A LM +LA++C C  RR + LK R+  +RLLSEA G+ ++  + YKEIE+ATN FSEKQ LG GAYGTVYAGKLH DEWVAIK+++HR  D +EQVMNE++L+SSV H NLVRLLGC IE GEQILVYEFM NGTL QHLQRER  GL W IRL           HLHSA+ PPIYHRDIKSSNILLD NF +K+ADFGLSR GM + SHISTAPQGTPGY+DPQYHQN+HLSDKSDVYSFGVVLVEIIT +K VDF R  +E+NLAALA DRIG+G ++EIIDP LEPH DAWTL SVH+V ELAFRCLAFHRDMRPSM EV  ELE I+LS W S
Sbjct:   46 VSYPFGFSEGCGIRLDCTESTGEIRIGEYIIQNVTSETLMVNFSMNCSRPIEDLQQFDRTNFGMTWRNGLLLHNCK--VPKSECTIPSEILSTRLNIQSCDSKKENVSCYSEARAD--YLDYQKLKNTGCGTVISSILIGMDNDTMKSSAMFIEFQTMEL---AWGLEGDCACHNDANCTNVSLPGNRKGFRCRCKDGFVGDGFSDGDGCRKVSR-CNPSRYLSGRCGGTTRIGVLVGGIIAGAGLMAALAVLCYCIRRRSASLKKRMSARRLLSEAAGSNSVHVFQYKEIERATNSFSEKQRLGIGAYGTVYAGKLHSDEWVAIKKLRHRDPDGVEQVMNEVKLLSSVSHPNLVRLLGCCIENGEQILVYEFMPNGTLAQHLQRERSSGLPWTIRLTIATETAHAIAHLHSAMNPPIYHRDIKSSNILLDYNFNSKVADFGLSRFGMTDDSHISTAPQGTPGYVDPQYHQNYHLSDKSDVYSFGVVLVEIITAMKVVDFSRSHSEINLAALAIDRIGKGRVDEIIDPFLEPHRDAWTLSSVHRVAELAFRCLAFHRDMRPSMTEVADELEQIRLSSWAS 617          

Query:   88 IGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKV--EHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGAS-LMISLALICCFIRRQ-SKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDE-WVAIKRIKHRG-NDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            + EFPI  +  + IR+ L+ +C+RP+ T + L++  +AP S NAILL NC+       C IP+I VQ  F++                     F D  K   + + C + LSSIS+   + +N S              GWWL G C C + A+C  + SP G  G+ C+C +G  GDGY AG+GC KGS  CN  K+LSGQCG   R  VLIG S LM++L L+CCFIRR+ S  KA+   K  LSEATG  NIP YPYKEIEKATN FS+KQ LGTGAYGTVYAGKLH++ WVAIKRIKHR  +DS+EQVMNEI+LISSV H +LVRLLGCSIE GEQ+LVYEFM NGTLCQHLQRE+GDGL+WP+RL           +LHSAI PPIYHRDIKSSNILLD NF++K+ADFGLSRLG  E SHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVL+EIIT LK VDF R  NEVNLAALATDRIG+G L EIIDPLL+ H DAWT  +VHKV ELAFRCLAF +D RPSMMEV AELE +++SRW    E     +               KPL+ + +  E   I L +    S+ ST+   KD+SPVSV
Sbjct:    3 VNEFPIVYVNQEKIRIDLRPKCDRPIDTFKSLFTKNFAPMSTNAILLNNCSS--TLLPCSIPDISVQTHFESLNCSKSSRSSISCLFNLTRDNFFDSGKYTDQLKYCDYFLSSISS---ESVNGSGVSLDILVLDL---GWWLPGKCQCSEQADCIKIASPKGP-GYRCRCKDGFSGDGYSAGTGCRKGS--CNLEKHLSGQCGETIRIAVLIGGSALMVALGLVCCFIRRRFSTSKAKGFRKLSLSEATG-INIPIYPYKEIEKATNSFSDKQRLGTGAYGTVYAGKLHNDIWVAIKRIKHRDIDDSVEQVMNEIKLISSVNHPSLVRLLGCSIENGEQVLVYEFMPNGTLCQHLQREKGDGLAWPVRLTIAAETAQAIAYLHSAIDPPIYHRDIKSSNILLDYNFRSKVADFGLSRLGRTEISHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLIEIITALKVVDFSRQYNEVNLAALATDRIGKGRLAEIIDPLLDIHCDAWTFSTVHKVAELAFRCLAFDKDTRPSMMEVAAELEQLRISRWSPEEEIKFRASSVESSCSTSSSNISEKPLSSTNNNGELGNISLFT-QVRSVKSTDE-AKDDSPVSV 605          

Query:   16 IHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG--CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG--------------------ASLMISLALICCFIRRQS-KLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRW--------PSSSEDNTYTAXXXXXXXXXXXXXXXKPLNIS---KSQSERSVILLQSGAAGSLNSTETLKKDNSPVS 1917
            + YPFGFS GC I L C    G + IGEF +Q ITP+ I + + + CNR +  ++ L+   + P+S N++LLQNC   +P +SC IP   ++ R               Y++  +D   L ++ +    CK + SS+          SA              WWLEG     C  NAN T V   NG  GF C C +G  GDG+ AG+GC K S+ C+ +KY+SG+CGG TR  VL+G                    A LM  LA +C ++RR+S  L+ RL  KRLL EA GN ++PF+ YKEIEKATNGFSEK  LG GAYGTVYAGKL+ D+ VAIK+++HR  DSI+QVMNEI+L+SSV H NLVRLLGC IE GE ILVYEFM NGTLCQHLQ+ERG GL W +RL           +LHSA+ PPIYHRDIKSSNILLD N+++K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVLVEIIT LKAVDF RP +EVNLAALA DRIGRGC++EIIDP L+P+ DAWTL S+  V ELAFRCLAFHRDMRP+M+EV  ELE I LS W        PS+S  ++                  K L++S   K+   R  +LL      SL S E   KD+SPVS
Sbjct:   49 VPYPFGFSRGCPIILQCNHTVGDVKIGEFQVQNITPNVIMINILADCNRSIERIKPLFGKNFGPSSNNSLLLQNCD--KPLNSCVIPTSSLR-RDLKLTNCDKNDNLNCYSQVPRDFDTLGYDNMTSTSCKSVFSSLFLG----WEGSAVSFQFGRVELE---WWLEGGYNNLCSNNANSTKVKLWNGRVGFRCHCADGFAGDGFAAGNGCRKVSK-CSASKYMSGECGGTTRVGVLVGVFAVTAPAFLAVHFSGLIAGALLMAGLAFLCYYVRRKSTSLRNRLSAKRLLCEAAGNSSVPFFQYKEIEKATNGFSEKHRLGIGAYGTVYAGKLNSDDLVAIKKLRHRDTDSIDQVMNEIKLLSSVSHPNLVRLLGCCIEEGEPILVYEFMPNGTLCQHLQQERGTGLPWTVRLTVATETAKAIAYLHSAMNPPIYHRDIKSSNILLDYNYRSKVADFGLSRLGMVESSHISTAPQGTPGYLDPQYHQYFHLSDKSDVYSFGVVLVEIITALKAVDFSRPHSEVNLAALAIDRIGRGCVDEIIDPYLDPNRDAWTLTSILSVAELAFRCLAFHRDMRPTMLEVAGELEQIMLSAWIPTMYMASPSASSCSSQNG-------------SQKSLSVSIGRKAGLARGKLLLPQ-RTDSLTSLEE-TKDSSPVS 692          

Query:   22 YPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNC---TDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG---CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIV---LIGASLMISLALIC-CFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKL-HDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRW-PSSSEDN 1743
            YPFGFS+GC IR +C+      IG+F +Q +T +SI V L   C R +  +  L+   +APTS N+ L++NC   TDG       + N+L     DA             + +    +F   + + +  C  L SSI+       +                GWWL+G C    C  N +CT V +P+G  G  C C +G  GDGY   + C +    C  +K +   C      IV   + GA L+ +LA    C  RR + L++ L  KRLLSEA GN ++ F+PYKEIEKAT+GFSEKQ LG GAYGTVY GKL +DEWVAIKR++HR ++S++QVMNEI+L+SSV H NLVRLLGC IE+G+ +LVYE+M NGTL +HLQR+RG GL W +RL           +LHS++ PPIYHRDIKS+NILLD +F +K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVL EIITGLK VDF RP  E+NLAALA D+IG GC++EIIDP+L+  +DAWTL S+H V ELAFRCLAFH DMRP+M EV  ELE I+LS W PS S D+
Sbjct:   59 YPFGFSNGCSIRFDCSAAEKPMIGDFSVQNVTENSIFVGLSHNCTRKIEDMNPLFGENFAPTSENSFLMENCNRTTDGCSIKQKFLENVLKLKSCDATGNISCFSLDSN-SSSKNSAKFFSMKTLRNSSCSLLFSSIAFE-----SVGVNAGIALEFERVRLGWWLKGGCESGTCAANTDCTDVETPHGYAGHRCSCLDGFHGDGYT--NPCQRALPECRGSKLVWRHCRSNLITIVGGTVGGAFLLAALAFFFFCKRRRSTPLRSHLSAKRLLSEAAGNSSVAFFPYKEIEKATDGFSEKQKLGIGAYGTVYRGKLQNDEWVAIKRLRHRDSESLDQVMNEIKLLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQIRLSGWIPSMSLDS 636          

Query:    7 TDPIHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTS-RNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG---CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFI------RRQSKLKARLC-TKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKL-HDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG-LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMA---ESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSS 1734
            T  + YPFGFS G  IR NC+  TG   IGEF +Q +T  +I V +   C R +  + QL+    AP+  +N IL+Q C     SS+C I N  V+ R +                T  DV  L  + V    CK+  SSIS S   +                   WWL+G+C    C +NA+C  V   +G  G  C C  G  G  +    GC +          L  +  G  + +VL  A +++ + +I   I       +QS    R     RLL E  GN ++PFY YKEIEKAT+ FS+K  LGTGAYGTVYAG+  +   VAIKR+KH+   SI+QV+NEI+L+SSV H NLVRLLGC    GE  LVYEFM NGTL QHLQ ERG   LSW +RL           HLHS++ PPIYHRDIKSSNILLD  F +K++DFGLSRLGM+   E+SHISTAPQGTPGYLDPQYHQ+F LSDKSDVYSFGVVLVEII+G K +DF RP +EVNLA+LA DRIGRG + +IIDP L   ++     S+H + ELAFRCL+FHR+MRP+M+E+T +L  IKL  + + S
Sbjct:   32 TSLLRYPFGFSDGYPIRFNCSEITGEAVIGEFAVQEVTNSNIYVEIPPVCKRNIRKIEQLFRENLAPSKLQNIILVQGCKKQNKSSNCLIRNKFVENRLNLSKCKSPVSCLDGATTTTADVMSLG-DVVNGSGCKYWFSSISQSQVSV-----------NLGRLKLDWWLKGSCSNTTCSENADCAKVKLDDGGLGHRCTCREGFSGKAFTVPGGCHR----------LVYKRKGLHKLVVLGTAGILVGVLVIVVLIATYFFRNKQSASSERASIANRLLCELAGNSSVPFYTYKEIEKATDSFSDKNMLGTGAYGTVYAGEFPNSSCVAIKRLKHKDTTSIDQVVNEIKLLSSVSHPNLVRLLGCCFADGEPFLVYEFMPNGTLYQHLQHERGQPPLSWQLRLAIACQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFNSKISDFGLSRLGMSTDFEASHISTAPQGTPGYLDPQYHQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLASLAVDRIGRGRVVDIIDPCLNKEINPKMFASIHNLAELAFRCLSFHRNMRPTMVEITEDLHRIKLMHYGTES 602          

Query:  586 CKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKLK------ARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWV-AIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERG---DGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRL-GMAES----SHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            C C  GL  D   A  G  +  + C   K      G     + ++G +L I++A+I      Q   K       +   + L + +TG  +   +  +EI KATN FS+   +GTG +G V+   L D  + AIKR K       +Q++NE+R++  V H++LVRLLGC ++    +L+YEF+ NGTL +HL          L+W  RL           +LHSA +PPIYHRD+KSSNILLD    AK++DFGLSRL  + E+    SHI T  QGT GYLDP+Y++NF L+DKSDVYSFGVVL+E++T  KA+DF R + +VNL       + +  L E IDPLL+   +   + ++ ++G LA  CL   R  RPSM EV  E+E I
Sbjct:  262 CSCKKGLEWDPVNAICGKCRHGKHCKKKKKTVVFAGAA---VAVVGVTLAIAVAVIGTKHSHQKVKKDIHKNIVKEREEMLSANSTGKSS-RIFTGREITKATNNFSKDNLIGTGGFGEVFKAVLEDGTITAIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLGCCVDLELPLLIYEFIPNGTLFEHLHGSSDRTWKPLTWRRRLQIAYQTAEGLAYLHSAAQPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERLTECIDPLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYI 646          

Query:  505 WLEGTCGCHKNANCTTVVSPNGT--QGFTCKCNNG-LLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKL---KARLCTKRLLSEATGNC-----------NIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQIL-VYEFMANGTLCQHLQRERGD--GLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            W   +C       C T     GT  Q F C C +G  L D    G    +   +    K +SG        + LI AS+   +     + RR++K     + L  + + S+ +               +  + Y+E+E+ATN F   + LG G +GTVY GKL D   VA+KR+        EQ  NE+ +++ +RH NLV L GCS ++   +L VYE++ANGTL  HL   + +   L W IRL           +LH++    I HRD+KS+NILLD NF  K+ADFGLSRL   + +H+STAPQGTPGY+DP YH  + LS+KSDVYSF VVL+E+I+ L AVD  RP+ E+NL+ +A  +I    L +++DP L    D     +V  V ELAF+CL   +D+RP M  V   L  I+
Sbjct:  214 WTANSC-----FRCITSGGRCGTDQQEFVCLCPDGPKLHDTCTNGKNDKRRRVIVKITKSISG---ASAAVVGLIAASIFWYV-----YHRRKTKSYRNSSALLPRNISSDPSAKSFDIEKAEELLVGVHIFSYEELEEATNNFDPSKELGDGGFGTVYYGKLKDGRSVAVKRLYDNNFKRAEQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVANGTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLHAS---KIIHRDVKSNNILLDQNFNVKVADFGLSRLFPMDKTHVSTAPQGTPGYVDPDYHLCYQLSNKSDVYSFAVVLMELISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAELAFQCLQSDKDLRPCMSHVQDTLTRIQ 620          

Query:  772 QSKLKARLCTKRLLS-EATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG------LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            QS    R   + LLS  +TG   I  +  KEI KAT+ F++   LG G +G V+ G L D   VA+KR K     SI Q++NE++++  V H+NLV+LLGC IE    +LVYEF+ NGTL +H+    G G      L    RL           +LHS+  PPIYHRD+KSSNILLD N   K+ADFGLSRLG+++ SH++T  QGT GYLDP+Y+ NF L+DKSDVYSFGVVL E++T  KA+DF R + +VNL       +  G L ++IDP++        + S+  +G LA  C+   R  RP+M     E+E I
Sbjct:  318 QSWASVRKLHRNLLSINSTGLDRI--FTGKEIVKATDNFAKSNLLGFGGFGEVFKGNLDDGTTVAVKRAKLGNEKSIYQIVNEVQILCQVSHKNLVKLLGCCIELEMPVLVYEFVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLFELLTCKKAIDFNREEEDVNLVVFVRKALKEGRLMDVIDPVIGIGATEKEIESMKALGVLAELCVKETRQCRPTMQVAAKEIENI 635          

Query:  523 GCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAG-----SGCWKG---SQVCNPAKYLSGQCGGKTRFI----VLIGASLMISLAL-------ICCFIRRQSKLKAR---------LCTKRLLSEATGNCNIP-FYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGL--SWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSED 1740
            GC  + N TT      T   TC C +G  G+ Y+ G     + C +G   + VC   K ++   G    +     ++IG S   S  +       +  FIRRQ +L  +         L  ++ L+   GN +    +  +E+EKAT  FS  + LG G  GTVY G L D   VA+K+ K    D +E+ +NE+ ++S + H+N+V+LLGC +E    ILVYEF+ NG L +HL  +  D    +W +RL           +LHSA   PIYHRDIKS+NI+LD   +AK++DFG SR    + +H++T   GT GY+DP+Y Q+   +DKSDVYSFGVVL E+ITG K+V F R Q    LA   T  +    L++IID  +    D   L  V    ++A +CL      RPSM +V+ ELE I+     S SED
Sbjct:  290 GCLCDYNSTT------TGYATCSCASGFEGNPYIPGECKDINECVRGIDGNPVCTAGKCVNLLGGYTCEYTNHRPLVIGLSTSFSTLVFIGGIYWLYKFIRRQRRLNQKKKFFKRNGGLLLQQQLTTTEGNVDSTRVFNSRELEKATENFSLTRILGEGGQGTVYKGMLVDGRIVAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETDVPILVYEFIPNGNLFEHLHDDSDDYTMTTWEVRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNIMLDEKHRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQSSQFTDKSDVYSFGVVLAELITGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIR---DGCKLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIR-----SYSED 713          

Query:  526 CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAG-----SGCWKGSQV----CNPAKYLSGQCGGK------------------------TRFIVLIGASLMISLALICCFIRRQSKLK-------------ARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEW-VAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG-LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSR 1719
            C  N+ C      NG   + C+CN G  G+ Y++      + C   S +    C+  K    + GG                         T  +++     ++ L  + C  +R   LK               + T+RL      N ++  +    ++KATNG++E + LG G  GTVY G L D   VAIK+ +   +  +EQ +NE+ ++S + H+N+V+LLGC +E    +LVYEF+ NGTL  HL     D  L+W  RL           +LHS+   PI HRDIK++NILLD N  AK+ADFG SRL   +   + T  QGT GYLDP+Y+    L++KSDVYSFGVVL+E+++G KA+ FKRPQ+  +L +          L+EII   +   M+   L  + +   +A  C     + RP M EV A+LE +++ +
Sbjct:  247 CGGNSTCLDSTPRNG---YICRCNEGFDGNPYLSAGCQDVNECTTSSTIHRHNCSDPKTCRNKVGGFYCKCQSGYRLDTTTMSCKRKEFAWTTILLVTTIGFLVILLGVACIQQRMKHLKDTKLREQFFEQNGGGMLTQRLSGAGPSNVDVKIFTEDGMKKATNGYAESRILGQGGQGTVYKGILPDNSIVAIKKARLGDSSQVEQFINEVLVLSQINHRNVVKLLGCCLETEVPLLVYEFITNGTLFDHLHGSMIDSSLTWEHRLKIAIEVAGTLAYLHSSASIPIIHRDIKTANILLDVNLTAKVADFGASRLIPMDKEELETMVQGTLGYLDPEYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFKRPQSSKHLVSYFATATKENRLDEIIGGEV---MNEDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALRVEK 686          

Query:  586 CKCNNGLLGDGYVAGSGCW--------KGSQVCNPAKYLSGQCGGKTRF------IVLIGASL-----MISLALICCFIRRQSKLKAR----------LCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGL--SWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKL 1713
            C C  G  G+ Y  G GC         +G   C   K ++ Q   K  +       + +GAS      ++ + L+  FI++Q KL  +          L  ++L+S          +  +E+EKAT  FS  + LG G  GTVY G L D   VA+K+ K    D +E+ +NE+ ++S + H+N+V+LLGC +E    +LVYEF+ NG L +HL  E  + +  +W IRL           +LHS+   PIYHRD+KS+NI+LD  ++AK++DFG SR    + +H++T   GT GY+DP+Y Q+   +DKSDVYSFGVVLVE+ITG K++ F R Q    LA      +    L +IID  +    D   L  V    ++A +CL      RPSM EV+ EL+ I++
Sbjct:  320 CSCTRGFQGNPYRLG-GCKDINECKEEEGMTYCGTNKCVNLQGHFKCVYNNHRPLAIGLGASFGSLIFVVGIYLLYKFIKKQRKLNQKKKFFKRNGGLLLQQQLISTVGMVEKTIVFSSRELEKATENFSSNRILGQGGQGTVYKGMLVDGRIVAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETKVPVLVYEFIPNGNLFEHLHDEFDENIMATWNIRLRIAIDIAGALSYLHSSASSPIYHRDVKSTNIMLDEKYRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQSSQFTDKSDVYSFGVVLVELITGEKSISFLRSQENRTLATYFILAMKENKLFDIIDARIR---DGCMLSQVTATAKVARKCLNLKGRKRPSMREVSMELDSIRM 723          

Query:  526 CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGS-----GCWKGSQVCNPAKYLSGQCGG-----------------------KTR-FIVLIGASLMISLALICCFI----RRQSKLKAR--------LCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEW-VAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG-LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSR 1719
            C KN++C    + NG   + CKCN G  G+ Y +        C   +  C+  K    + GG                       +TR F+V+I   L++ LA IC       R+ +KL+ +        +  +RL      N +   +  + +++ATNG+ E + LG G  GTVY G L D   VAIK+ +   +  ++Q ++E+ ++S + H+N+V++LGC +E    +LVYEF+ NGTL  HL     D  L+W  RL           +LHS+   PI HRDIK++NILLD N  AK+ADFG S+L   +   ++T  QGT GYLDP+Y+    L++KSDVYSFGVVL+E+++G KA+ F+RPQ   +L +          L+EIID   +  ++   L  + +   +A  C     + RP M EV A+LE +++ +
Sbjct:  258 CGKNSSCYNSTTRNG---YICKCNEGYDGNPYRSEGCKDIDECISDTHNCSDPKTCRNRDGGFDCKCPSGYDLNSSMSCTRPEYKRTRIFLVIIIGVLVLLLAAICIQHATKQRKYTKLRRQFFEQNGGGMLIQRLSGAGLSNIDFKIFTEEGMKEATNGYDESRILGQGGQGTVYKGILPDNTIVAIKKARLADSRQVDQFIHEVLVLSQINHRNVVKILGCCLETEVPLLVYEFITNGTLFDHLHGSIFDSSLTWEHRLRIAIEVAGTLAYLHSSASIPIIHRDIKTANILLDENLTAKVADFGASKLIPMDKEQLTTMVQGTLGYLDPEYYTTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQASKHLVSYFVSATEENRLHEIID---DQVLNEDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALRVEK 692          

Query:  502 WWLEG-TCG------CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCW----------------KGSQVCNPAKYLSGQCGGKTRF---------------------IVLIGASL--MISLALICCFIRRQSKLK-------------ARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEW-VAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG-LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSR 1719
            W + G TCG      C  N  C+   S +G  G+TCKC  G  G+ Y+  +GC                  G   C   K    +C  ++R+                      +++G ++  ++ L  I C   +    K               +  +RL      N ++  +  + +++AT+G+ E + LG G  GTVY G L D   VAIK+ +   N  +EQ +NE+ ++S + H+N+V+LLGC +E    +LVYEF+++GTL  HL     D  L+W  RL           +LHS+   PI HRDIK++NILLD N  AK+ADFG SRL   +   ++T  QGT GYLDP+Y+    L++KSDVYSFGVVL+E+++G KA+ F+RPQ   ++ +          L+EIID  +   M+      + K   +A  C     + RP M EV AELE +++++
Sbjct:  229 WSIRGETCGQVGEKKCGVNGICSN--SASGI-GYTCKCKGGFQGNPYLQ-NGCQDINECTTANPIHKHNCSGDSTCEN-KLGHFRCNCRSRYELNTTTNTCKPKGNPEYVEWTTIVLGTTIGFLVILLAISCIEHKMKNTKDTELRQQFFEQNGGGMLMQRLSGAGPSNVDVKIFTEEGMKEATDGYDENRILGQGGQGTVYKGILPDNSIVAIKKARLGDNSQVEQFINEVLVLSQINHRNVVKLLGCCLETEVPLLVYEFISSGTLFDHLHGSMFDSSLTWEHRLRMAVEIAGTLAYLHSSASIPIIHRDIKTANILLDENLTAKVADFGASRLIPMDKEDLATMVQGTLGYLDPEYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQTSKHIVSYFASATKENRLHEIIDGQV---MNENNQREIQKAARIAVECTRLTGEERPGMKEVAAELEALRVTK 687          

Query:   22 YPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNC---TDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG---CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIV---LIGASLMISLALIC-CFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKL-HDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRW-PSSSEDN 1743
            YPFGFS+GC IR +C+      IG+F +Q +T +SI V L   C R +  +  L+   +APTS N+ L++NC   TDG       + N+L     DA             + +    +F   + + +  C  L SSI+       +                GWWL+G C    C  N +CT V +P+G  G  C C +G  GDGY   + C +    C  +K +   C      IV   + GA L+ +LA    C  RR + L++ L  KRLLSEA GN ++ F+PYKEIEKAT+GFSEKQ LG GAYGTVY GKL +DEWVAIKR++HR ++S++QVMNEI+L+SSV H NLVRLLGC IE+G+ +LVYE+M NGTL +HLQR+RG GL W +RL           +LHS++ PPIYHRDIKS+NILLD +F +K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVL EIITGLK VDF RP  E+NLAALA D+IG GC++EIIDP+L+  +DAWTL S+H V ELAFRCLAFH DMRP+M EV  ELE I+LS W PS S D+
Sbjct:   59 YPFGFSNGCSIRFDCSAAEKPMIGDFSVQNVTENSIFVGLSHNCTRKIEDMNPLFGENFAPTSENSFLMENCNRTTDGCSIKQKFLENVLKLKSCDATGNISCFSLDSN-SSSKNSAKFFSMKTLRNSSCSLLFSSIAFE-----SVGVNAGIALEFERVRLGWWLKGGCESGTCAANTDCTDVETPHGYAGHRCSCLDGFHGDGYT--NPCQRALPECRGSKLVWRHCRSNLITIVGGTVGGAFLLAALAFFFFCKRRRSTPLRSHLSAKRLLSEAAGNSSVAFFPYKEIEKATDGFSEKQKLGIGAYGTVYRGKLQNDEWVAIKRLRHRDSESLDQVMNEIKLLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQIRLSGWIPSMSLDS 636          

Query:   22 YPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNC---TDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG---CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIV---LIGASLMISLALIC-CFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKL-HDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRW-PSSSEDN 1743
            YPFGFS+GC IR +C+      IG+F +Q +T +SI V L   C R +  +  L+   +APTS N+ L++NC   TDG       + N+L     DA             + +    +F   + + +  C  L SSI+       +                GWWL+G C    C  N +CT V +P+G  G  C C +G  GDGY   + C +    C  +K +   C      IV   + GA L+ +LA    C  RR + L++ L  KRLLSEA GN ++ F+PYKEIEKAT+GFSEKQ LG GAYGTVY GKL +DEWVAIKR++HR ++S++QVMNEI+L+SSV H NLVRLLGC IE+G+ +LVYE+M NGTL +HLQR+RG GL W +RL           +LHS++ PPIYHRDIKS+NILLD +F +K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVL EIITGLK VDF RP  E+NLAALA D+IG GC++EIIDP+L+  +DAWTL S+H V ELAFRCLAFH DMRP+M EV  ELE I+LS W PS S D+
Sbjct:   59 YPFGFSNGCSIRFDCSAAEKPMIGDFSVQNVTENSIFVGLSHNCTRKIEDMNPLFGENFAPTSENSFLMENCNRTTDGCSIKQKFLENVLKLKSCDATGNISCFSLDSN-SSSKNSAKFFSMKTLRNSSCSLLFSSIAFE-----SVGVNAGIALEFERVRLGWWLKGGCESGTCAANTDCTDVETPHGYAGHRCSCLDGFHGDGYT--NPCQRALPECRGSKLVWRHCRSNLITIVGGTVGGAFLLAALAFFFFCKRRRSTPLRSHLSAKRLLSEAAGNSSVAFFPYKEIEKATDGFSEKQKLGIGAYGTVYRGKLQNDEWVAIKRLRHRDSESLDQVMNEIKLLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQIRLSGWIPSMSLDS 636          

Query:    7 TDPIHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTS-RNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG---CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFI------RRQSKLKARLC-TKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKL-HDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG-LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMA---ESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSS 1734
            T  + YPFGFS G  IR NC+  TG   IGEF +Q +T  +I V +   C R +  + QL+    AP+  +N IL+Q C     SS+C I N  V+ R +                T  DV  L  + V    CK+  SSIS S   +                   WWL+G+C    C +NA+C  V   +G  G  C C  G  G  +    GC +          L  +  G  + +VL  A +++ + +I   I       +QS    R     RLL E  GN ++PFY YKEIEKAT+ FS+K  LGTGAYGTVYAG+  +   VAIKR+KH+   SI+QV+NEI+L+SSV H NLVRLLGC    GE  LVYEFM NGTL QHLQ ERG   LSW +RL           HLHS++ PPIYHRDIKSSNILLD  F +K++DFGLSRLGM+   E+SHISTAPQGTPGYLDPQYHQ+F LSDKSDVYSFGVVLVEII+G K +DF RP +EVNLA+LA DRIGRG + +IIDP L   ++     S+H + ELAFRCL+FHR+MRP+M+E+T +L  IKL  + + S
Sbjct:   32 TSLLRYPFGFSDGYPIRFNCSEITGEAVIGEFAVQEVTNSNIYVEIPPVCKRNIRKIEQLFRENLAPSKLQNIILVQGCKKQNKSSNCLIRNKFVENRLNLSKCKSPVSCLDGATTTTADVMSLG-DVVNGSGCKYWFSSISQSQVSV-----------NLGRLKLDWWLKGSCSNTTCSENADCAKVKLDDGGLGHRCTCREGFSGKAFTVPGGCHR----------LVYKRKGLHKLVVLGTAGILVGVLVIVVLIATYFFRNKQSASSERASIANRLLCELAGNSSVPFYTYKEIEKATDSFSDKNMLGTGAYGTVYAGEFPNSSCVAIKRLKHKDTTSIDQVVNEIKLLSSVSHPNLVRLLGCCFADGEPFLVYEFMPNGTLYQHLQHERGQPPLSWQLRLAIACQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFNSKISDFGLSRLGMSTDFEASHISTAPQGTPGYLDPQYHQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLASLAVDRIGRGRVVDIIDPCLNKEINPKMFASIHNLAELAFRCLSFHRNMRPTMVEITEDLHRIKLMHYGTES 602          

Query:  586 CKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKLK------ARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWV-AIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERG---DGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRL-GMAES----SHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            C C  GL  D   A  G  +  + C   K      G     + ++G +L I++A+I      Q   K       +   + L + +TG  +   +  +EI KATN FS+   +GTG +G V+   L D  + AIKR K       +Q++NE+R++  V H++LVRLLGC ++    +L+YEF+ NGTL +HL          L+W  RL           +LHSA +PPIYHRD+KSSNILLD    AK++DFGLSRL  + E+    SHI T  QGT GYLDP+Y++NF L+DKSDVYSFGVVL+E++T  KA+DF R + +VNL       + +  L E IDPLL+   +   + ++ ++G LA  CL   R  RPSM EV  E+E I
Sbjct:  262 CSCKKGLEWDPVNAICGKCRHGKHCKKKKKTVVFAGAA---VAVVGVTLAIAVAVIGTKHSHQKVKKDIHKNIVKEREEMLSANSTGKSS-RIFTGREITKATNNFSKDNLIGTGGFGEVFKAVLEDGTITAIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLGCCVDLELPLLIYEFIPNGTLFEHLHGSSDRTWKPLTWRRRLQIAYQTAEGLAYLHSAAQPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERLTECIDPLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYI 646          

Query:  718 IGASLMISLALICCFI-------RRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG---LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            IG S+++ + L+  F        R+     +R  +K  +  +     IP + YKE++ AT+ FS+ + LG G +GTVY GK+ D   VA+KR+       +EQ MNEI +++ + H+NLV L GC+  R  E +LVYEF+ NGT+  HL  E       L+W +RL           +LH++    I HRD+K++NILLD NF  K+ADFGLSRL  ++ +H+STAPQGTPGY+DP+YH+ +HL+DKSDVYSFGVVLVE+I+   AVD  R ++E+NL++LA ++I     +E+ID  L    +         V ELAF+CL     MRP+M +V  EL+ I+
Sbjct:  229 IGGSVILIIILVALFAVIHRNYRRKDGSELSRDNSKSDVEFSQVFFKIPIFSYKELQAATDNFSKDRLLGDGGFGTVYYGKVRDGREVAVKRLYEHNYRRLEQFMNEIEILTRLHHKNLVSLYGCTSRRSRELLLVYEFIPNGTVADHLYGENTPHQGFLTWSMRLSIAIETASALAYLHAS---DIIHRDVKTTNILLDRNFGVKVADFGLSRLLPSDVTHVSTAPQGTPGYVDPEYHRCYHLTDKSDVYSFGVVLVELISSKPAVDISRCKSEINLSSLAINKIQNHATHELIDQNLGYATNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQVVHELKGIQ 568          

Query:  505 WLEGTCGCHKNANCTTVVSPNGT--QGFTCKCNNG-LLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKL---KARLCTKRLLSEATGNC-----------NIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQIL-VYEFMANGTLCQHLQRERGD--GLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            W   +C       C T     GT  Q F C C +G  L D    G    +   +    K +SG        + LI AS+   +     + RR++K     + L  + + S+ +               +  + Y+E+E+ATN F   + LG G +GTVY GKL D   VA+KR+        EQ  NE+ +++ +RH NLV L GCS ++   +L VYE++ANGTL  HL   + +   L W IRL           +LH++    I HRD+KS+NILLD NF  K+ADFGLSRL   + +H+STAPQGTPGY+DP YH  + LS+KSDVYSF VVL+E+I+ L AVD  RP+ E+NL+ +A  +I    L +++DP L    D     +V  V ELAF+CL   +D+RP M  V   L  I+
Sbjct:  214 WTANSC-----FRCITSGGRCGTDQQEFVCLCPDGPKLHDTCTNGKNDKRRRVIVKITKSISG---ASAAVVGLIAASIFWYV-----YHRRKTKSYRNSSALLPRNISSDPSAKSFDIEKAEELLVGVHIFSYEELEEATNNFDPSKELGDGGFGTVYYGKLKDGRSVAVKRLYDNNFKRAEQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVANGTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLHAS---KIIHRDVKSNNILLDQNFNVKVADFGLSRLFPMDKTHVSTAPQGTPGYVDPDYHLCYQLSNKSDVYSFAVVLMELISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAELAFQCLQSDKDLRPCMSHVQDTLTRIQ 620          

Query:  838 IPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQIL-VYEFMANGTLCQHLQRERGD--GLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            +  + Y+E+E+ATN F   + LG G +GTVY GKL D   VA+KR+        EQ  NE+ +++ +RH NLV L GCS ++   +L VYE++ANGTL  HL   + +   L W IRL           +LH++    I HRD+KS+NILLD NF  K+ADFGLSRL   + +H+STAPQGTPGY+DP YH  + LS+KSDVYSF VVL+E+I+ L AVD  RP+ E+NL+ +A  +I    L +++DP L    D     +V  V ELAF+CL   +D+RP M  V   L  I+
Sbjct:  323 VHIFSYEELEEATNNFDPSKELGDGGFGTVYYGKLKDGRSVAVKRLYDNNFKRAEQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVANGTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLHAS---KIIHRDVKSNNILLDQNFNVKVADFGLSRLFPMDKTHVSTAPQGTPGYVDPDYHLCYQLSNKSDVYSFAVVLMELISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAELAFQCLQSDKDLRPCMSHVQDTLTRIQ 614          

Query:  541 NCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCN----------------------------------IPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            NCT ++ P+G+         G +G G+ +G                             +GA+L I   L+C FIRR+ KL  +   K L +    + N                                  I  + Y+E+E+AT  FS++  LG G +GTVY G L D   VA+KR+  R    +EQ  NEI ++ S++H NLV L GC+     E +LVYE+++NGTL +HL   +     + WP RL           +LH++    I HRD+K++NILLD N++ K+ADFGLSRL   + +HISTAPQGTPGY+DP+Y+Q + L++KSDVYSFGVVL E+I+  +AVD  R ++++NLA +A  +I    ++E+ D  L    D      +  V ELAFRCL   RD+RPSM E+   L +I+
Sbjct:  242 NCTPMM-PSGSSAHAGLSKKGKIGIGFASG----------------------------FLGATL-IGGCLLCIFIRRRKKLATQYTNKGLSTTTPYSSNYTMSNTPTSTTISGSNHSLVPSISNLGNGSVYSGIQVFSYEELEEATENFSKE--LGDGGFGTVYYGTLKDGRAVAVKRLFERSLKRVEQFKNEIDILKSLKHPNLVILYGCTTRHSRELLLVYEYISNGTLAEHLHGNQAQSRPICWPARLQIAIETASALSYLHAS---GIIHRDVKTTNILLDSNYQVKVADFGLSRLFPMDQTHISTAPQGTPGYVDPEYYQCYRLNEKSDVYSFGVVLSELISSKEAVDITRHRHDINLANMAISKIQNDAVHELADLSLGFARDPSVKKMMSSVAELAFRCLQQERDVRPSMDEIVEVLRVIQ 634          

Query:  811 LSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            L+  +  C +  + Y+E+E+AT  FS +  LG G +GTVY G L D   VA+KR+  R    +EQ  NEI ++ S++H NLV L GC+     E +LVYE+++NGTL +HL   R +   L W  RL            LH  IK  I HRDIK++NILLD N++ K+ADFGLSRL   + +HISTAPQGTPGY+DP+Y+Q + L++KSDVYSFGVVL E+I+  +AVD  R ++++NLA +A  +I    L+E++D  L    D      +  V ELAFRCL   RD+RP+M E+   L  IK
Sbjct:  945 LANRSDYCGVQVFSYEELEEATENFSRE--LGDGGFGTVYYGVLKDGRAVAVKRLYERSLKRVEQFKNEIEILKSLKHPNLVILYGCTSRHSRELLLVYEYISNGTLAEHLHGNRAEARPLCWSTRLNIAIETASALSFLH--IKG-IIHRDIKTTNILLDDNYQVKVADFGLSRLFPMDQTHISTAPQGTPGYVDPEYYQCYQLNEKSDVYSFGVVLTELISSKEAVDITRHRHDINLANMAVSKIQNNALHELVDSSLGYDNDPEVRRKMMAVAELAFRCLQQERDVRPAMDEIVEILRGIK 1243          

Query:  772 QSKLKARLCTKRLLS-EATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG------LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            QS    R   + LLS  +TG   I  +  KEI KAT+ F++   LG G +G V+ G L D   VA+KR K     SI Q++NE++++  V H+NLV+LLGC IE    +LVYEF+ NGTL +H+    G G      L    RL           +LHS+  PPIYHRD+KSSNILLD N   K+ADFGLSRLG+++ SH++T  QGT GYLDP+Y+ NF L+DKSDVYSFGVVL E++T  KA+DF R + +VNL       +  G L ++IDP++        + S+  +G LA  C+   R  RP+M     E+E I
Sbjct:  318 QSWASVRKLHRNLLSINSTGLDRI--FTGKEIVKATDNFAKSNLLGFGGFGEVFKGNLDDGTTVAVKRAKLGNEKSIYQIVNEVQILCQVSHKNLVKLLGCCIELEMPVLVYEFVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLFELLTCKKAIDFNREEEDVNLVVFVRKALKEGRLMDVIDPVIGIGATEKEIESMKALGVLAELCVKETRQCRPTMQVAAKEIENI 635          

Query:    4 GTDPIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG---ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSE---RSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            GT  + YPFGFS  C+I LNC+ +  + I +FP+Q +  D+I++ L+ RC RP+  L  L +  YAP S NAILL NCT G   S C IP+I V+  F++            +++      F D+       CK+LLSSISA       S                WWL+G C C K+A CT V SP G+ GF C+C +GL+GDGY+AG GC K +  CNPAKYLSGQCG   R  VL+G   A++ + L L CC  RR S  KA+   K   +EA  + +IP YPYKEIEKATN FSEKQ +GTGAYGTVYAGKL  D WVAIKRIKHR  DSIEQV+NEI+LISSV H NLVRLLGCSIE  EQILVYEFM NGTLCQHLQR RGDGL WP+RL           HLHSAI PPIYHRDIKSSNILLD +FK+K+ADFGLSR GM + SHIST PQGTPGYLDPQYHQNFHLSDK+DVYSFGVVL+EIIT  K +DF RPQ+EVNLA+LA D+IGRG L+EIIDP L+ H DAWT  SVHKV ELAFRCLAFH+D+RPSMMEV AELE I L+RWP S E N  T                K LN++  ++E   R +++LQ+ A  S  STE     NSP+SV
Sbjct:   34 GTSHLPYPFGFSANCDIHLNCSLNGEMLINDFPVQIVGQDTIKINLEPRCYRPVEALYNLSTKNYAPKSTNAILLNNCTSG--FSPCNIPSISVRTHFESLNCSNNSSVSC-FSKADTANGFFDYNMANISQCKYLLSSISAE------SFTGSGVSLETQMMELWWWLQGDCQCSKDAICTKVESPAGS-GFRCQCRDGLIGDGYLAGVGCRKAAG-CNPAKYLSGQCGAGARPAVLLGGIVAAVGVGLGLFCCLTRRNSISKAKSFRKLHRAEAA-DISIPIYPYKEIEKATNSFSEKQRIGTGAYGTVYAGKLSSDSWVAIKRIKHRDVDSIEQVINEIKLISSVSHPNLVRLLGCSIENDEQILVYEFMPNGTLCQHLQRVRGDGLDWPVRLAIATETAKAIAHLHSAIDPPIYHRDIKSSNILLDFDFKSKVADFGLSRHGMTDMSHISTVPQGTPGYLDPQYHQNFHLSDKTDVYSFGVVLIEIITAKKVLDFSRPQDEVNLASLAIDKIGRGLLDEIIDPFLDLHSDAWTFSSVHKVAELAFRCLAFHKDIRPSMMEVAAELEQIMLTRWPPSEEINC-TTSLDFSQCSSSSHVSEKALNLTVKKTEIERRGLLVLQTQA--SRKSTER-TDHNSPMSV 663          

Query:   82 IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQV-------CNPAKYLSGQCGGKTRFIVLIG---ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSE---RSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            + I EFP+Q +  +SI++ L+ +CNRPL  L  L++  YAP S NAILL NCT     S C IP+I VQ  F++              E   +  F D+       C++ LSSISA       S                WWL+G C C K+A CT V SP G+ GF C+C +GL+GDGY+AG GC KGS +       CNPAKYLSGQCGG +   VL+G   A + +SL L CC +RR S  KA+   K  LSEA  + NIP YPYKEIEKATN FSEKQ +GTGAYGTVYAGKL+ D WVAIKRIKH   D+IEQVMNEI+LISSV H NLVRLLGCSIE GEQILVYEFM NGTLCQHLQRERGDGL WP+RL           HLHSA+ PPIYHRDIKSSNILLD +F++K+ADFGLSR GM E SHIST PQGTPGYLDPQYH NFHLSDKSDVYSFGVVLVEIIT  K VDF RPQNEVNLAALATDRIGRG L+EIIDP L+ H DAWT  SVHKV E+AFRCLAFH+DMRPSMMEV AELE I LSRW SS E N                   KPLN +  ++E   R + +LQ+    S  STE     NSPVSV
Sbjct:    1 MLINEFPVQIVGQNSIKIILEPKCNRPLEALDNLFTKNYAPKSTNAILLHNCTSAV--SPCNIPSINVQTHFESLKCSNNSSLSCFSKEVTAN-GFFDYNMANISQCQYFLSSISAE------SFTGSGVSLEIQMMELWWWLQGDCRCSKDAICTQVESPAGS-GFRCQCRDGLIGDGYLAGVGCRKGSFLDVKASAGCNPAKYLSGQCGGGSGAAVLLGGVVAGVGVSLGLFCCLVRRNSASKAKSFRKLHLSEAA-DINIPIYPYKEIEKATNSFSEKQRIGTGAYGTVYAGKLNSDSWVAIKRIKHGDMDNIEQVMNEIKLISSVSHPNLVRLLGCSIENGEQILVYEFMPNGTLCQHLQRERGDGLDWPVRLAIAADTAKAIAHLHSAMDPPIYHRDIKSSNILLDYHFRSKVADFGLSRHGMTEISHISTVPQGTPGYLDPQYHLNFHLSDKSDVYSFGVVLVEIITAKKVVDFSRPQNEVNLAALATDRIGRGRLDEIIDPFLDLHSDAWTFSSVHKVAEVAFRCLAFHKDMRPSMMEVAAELEQILLSRWASSEETNC-AISLDFSPCSSSSNVSDKPLNSTVKKTEIERRGLFVLQTQT--SKKSTER-ANHNSPVSV 612          

Query:   16 IHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG--CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG--------------------ASLMISLALICCFIRRQS-KLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRW--------PSSSEDNTYTAXXXXXXXXXXXXXXXKPLNIS---KSQSERSVILLQSGAAGSLNSTETLKKDNSPVS 1917
            + YPFGFS GC I L C    G + IGEF +Q ITP+ I + + + CNR +  ++ L+   + P+S N++LLQNC   +P +SC IP   ++ R               Y++  +D   L ++ +    CK + SS+          SA              WWLEG     C  NAN T V   NG  GF C C +G  GDG+ AG+GC K S+ C+ +KY+SG+CGG TR  VL+G                    A LM  LA +C ++RR+S  L+ RL  KRLL EA GN ++PF+ YKEIEKATNGFSEK  LG GAYGTVYAGKL+ D+ VAIK+++HR  DSI+QVMNEI+L+SSV H NLVRLLGC IE GE ILVYEFM NGTLCQHLQ+ERG GL W +RL           +LHSA+ PPIYHRDIKSSNILLD N+++K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVLVEIIT LKAVDF RP +EVNLAALA DRIGRGC++EIIDP L+P+ DAWTL S+  V ELAFRCLAFHRDMRP+M+EV  ELE I LS W        PS+S  ++                  K L++S   K+   R  +LL      SL S E   KD+SPVS
Sbjct:   49 VPYPFGFSRGCPIILQCNHTVGDVKIGEFQVQNITPNVIMINILADCNRSIERIKPLFGKNFGPSSNNSLLLQNCD--KPLNSCVIPTSSLR-RDLKLTNCDKNDNLNCYSQVPRDFDTLGYDNMTSTSCKSVFSSLFLG----WEGSAVSFQFGRVELE---WWLEGGYNNLCSNNANSTKVKLWNGRVGFRCHCADGFAGDGFAAGNGCRKVSK-CSASKYMSGECGGTTRVGVLVGVFAVTAPAFLAVHFSGLIAGALLMAGLAFLCYYVRRKSTSLRNRLSAKRLLCEAAGNSSVPFFQYKEIEKATNGFSEKHRLGIGAYGTVYAGKLNSDDLVAIKKLRHRDTDSIDQVMNEIKLLSSVSHPNLVRLLGCCIEEGEPILVYEFMPNGTLCQHLQQERGTGLPWTVRLTVATETAKAIAYLHSAMNPPIYHRDIKSSNILLDYNYRSKVADFGLSRLGMVESSHISTAPQGTPGYLDPQYHQYFHLSDKSDVYSFGVVLVEIITALKAVDFSRPHSEVNLAALAIDRIGRGCVDEIIDPYLDPNRDAWTLTSILSVAELAFRCLAFHRDMRPTMLEVAGELEQIMLSAWIPTMYMASPSASSCSSQNG-------------SQKSLSVSIGRKAGLARGKLLLPQ-RTDSLTSLEE-TKDSSPVS 692          

Query:   16 IHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXX-YAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCG---CHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQS-KLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRW--------PSSSEDNTYTAXXXXXXXXXXXXXXXKPLNIS--KSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            + YPFGFS+GC I+LNC    G I IGEF +Q ITP+ I V L + CNR + T+R L+   Y P+ +N++LLQNC+  +PS+SC I     Q    +             Y+     +  L +E V    C  + SS++      + S                WWLEG C    C KNANC+ V   NGT GF C C +G  GDG+  G+GC +G        Y+           ++ GASLM   AL+C F++++S  ++ R   KRLL EA GN ++PF+ YKEIE+ATNGFSEKQ LGTGAYGTVY+GKLH D+ VAIK+IK R  DS++ VMNEI+L+SSV H NLVRLLGC +E GE ILVYEFM NGTLCQHLQRERG+GL W +RL           +LHS + PPIYHRDIKSSNILLD N+++K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVLVEIIT  K VDF RP +EVNLAALA DRIGRGC++EI+DP L+P  DAWTL S+H V ELAFRCLAFHRDMRP+MMEV  ELE I+LS W        PSSS                      K L +S  K  +  S  LL      SL S E + KD+SPVSV
Sbjct:   48 VPYPFGFSNGCPIQLNCESTEGEIKIGEFQVQNITPNGILVNLPADCNRSIETIRPLFGLNYGPSWQNSLLLQNCS--KPSNSCVISRSPFQGELHSKNCEAAKNDNLSCYSLPYSGIDTLSYEGVNSTQCSSVFSSLALGSDSPVVSFQYERIELE-------WWLEGHCRDTFCSKNANCSEVKLQNGTVGFRCHCYDGFAGDGFTTGNGCRRGEPTW---LYICLHLFLLFIMRLIAGASLMAVFALLCYFVKKKSTSMRNRSSAKRLLCEAAGNSSVPFFQYKEIERATNGFSEKQRLGTGAYGTVYSGKLHNDDLVAIKKIKQRDTDSLDLVMNEIKLLSSVSHPNLVRLLGCCLEEGEPILVYEFMPNGTLCQHLQRERGNGLPWTVRLTVAAETANAIAYLHSVVNPPIYHRDIKSSNILLDYNYRSKVADFGLSRLGMEESSHISTAPQGTPGYLDPQYHQYFHLSDKSDVYSFGVVLVEIITAQKVVDFSRPHSEVNLAALAIDRIGRGCVDEIVDPYLDPDRDAWTLSSIHSVAELAFRCLAFHRDMRPTMMEVAEELEQIRLSAWVPTMHMASPSSSS-------------HFSDHGSQKSLGVSVGKKAAVASRRLLVPQRTDSLTSLEEV-KDSSPVSV 673          

Query:  526 CHKNANCT--TVVSPNGTQGFT-CKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFI------RRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWV-AIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG----LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLL---EPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELE 1701
            C+   +C+  +   P G  G + C CN G   D  V G+ C++       A  L  +        V IG    IS   I   I      +R ++ K     + +L  +    N   +  KE++KATNGFS+ + LG+G +G VY G+L D  V A+K  K     S +QV+NE+ ++S V H+NLVRLLGC +E  + +++YE+++NGTL  HL    G+G    L W  RL           +LHS    PIYHRD+KS+NILLD  F AK++DFGLSRL     SH+ST  QGT GYLDP+Y++N+ L+DKSDVYS+GVVL+E++T  KA+DF R Q++VNLA   +     G + E++D  L   EP  +   L SV    ELAF CL   +  RPSM EV  +LE
Sbjct:  236 CNSKLDCSGPSKCLPAGRSGLSRCLCNRGYYWDR-VRGT-CFRNKHKSKAAGLLGLE--------VSIGVICFISFGAIIVLITVRKSSKRFNQAKLDKAREDMLKSSDSGKNARMFQLKEVKKATNGFSQDRILGSGGFGQVYKGELQDGTVVAVKSAKVGNLKSTQQVLNEVGILSQVNHKNLVRLLGCCVEGEQPLMIYEYISNGTLYDHLH---GNGSSTFLGWRERLRIAWQTAEALAYLHSGTYTPIYHRDVKSTNILLDDEFNAKVSDFGLSRLARPGLSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSYGVVLLELLTSQKAIDFSRDQDDVNLAIYVSQAAKNGAIMEVVDQRLTGTEPSSN--VLNSVQLFSELAFACLREKKADRPSMREVVQQLE 629          

Query:  718 IGASLMISLALICCFIRRQSKLKARLCTKRL-----------LSEATGNCN---IPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGC-SIERGEQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            +G   M+ + L+  F  R  + K +  +  +            S+  G+ N   +P + Y E+E+ATN F  K  LG G +GTVY GKL D   VA+KR+       I+Q MNEI++++ +RH+NLV L GC S    E +LVYE++ NGT+  HL  +R     L+W IR+           +LH+     I HRD+K++NILLD NF  K+ADFGLSRL   + +HISTAPQGTPGYLDP+YHQ + L+ KSDVYSFGVVL+E+I+ + AVD  R Q+E+NLA LA ++I +   +E+IDP L    D         V ELAF CL   +++RP M EV  EL+ ++
Sbjct:  280 LGVPFMVLIILVSVFFIRWHRHKRKHISSNVNSANASSDPSSKSDPEGDSNYFGVPIFSYSELEEATNNFDSKHELGDGGFGTVYYGKLRDGREVAVKRLYEHNRKRIKQFMNEIQILTRLRHKNLVSLYGCTSCYSRELLLVYEYIPNGTVADHLHHDRAKSGSLTWTIRMRIAIETAGALAYLHAT---DIIHRDVKTNNILLDNNFCVKVADFGLSRLFPNDVTHISTAPQGTPGYLDPEYHQCYQLTAKSDVYSFGVVLIELISSMPAVDMTRNQHEINLATLAMNKIQKCAFDELIDPYLGYKSDEEIKRMTTSVAELAFLCLQQGKEIRPGMNEVLKELKAME 625          

Query:  814 SEATGNCN---IPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGC-SIERGEQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            S+  G+ N   +P + Y E+E+ATN F  K  LG G +GTVY GKL D   VA+KR+       I+Q MNEI++++ +RH+NLV L GC S    E +LVYE++ NGT+  HL  +R     L+W IR+           +LH+     I HRD+K++NILLD NF  K+ADFGLSRL   + +HISTAPQGTPGYLDP+YHQ + L+ KSDVYSFGVVL+E+I+ + AVD  R Q+E+NLA LA ++I +   +E+IDP L    D         V ELAF CL   +++RP M EV  EL+ ++
Sbjct:  275 SDPEGDTNYFGVPIFSYSELEEATNNFDSKHELGDGGFGTVYYGKLRDGREVAVKRLYEHNRKRIKQFMNEIQILTRLRHKNLVSLYGCTSCYSRELLLVYEYIPNGTVADHLHHDRAKSGSLTWTIRMRIAIETAGALAYLHAT---DIIHRDVKTNNILLDNNFCVKVADFGLSRLFPNDVTHISTAPQGTPGYLDPEYHQCYQLTAKSDVYSFGVVLIELISSMPAVDMTRDQHEINLATLAMNKIQKCAFDELIDPYLGYKSDEEIKRMTTSVAELAFLCLQQGKEIRPCMNEVLKELKAME 577          

Query:  835 NIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG--LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI---KLSRWPSSSEDN 1743
            +IP + Y E+ +ATN F  ++ +G G +GTVY GKL D   VA+KR+       ++Q MNEI +++ + H+NLV L GC+  R  E +LVYE++ NGT+  HL  ++     L+WPIR+           +LH++    I HRD+K++NILLD NF  K+ADFGLSRL   + +H+ST PQGTPGY+DP+YHQ++ L+DKSDVYSFGVVL+E+I+ + AVD  R ++E+NL+ LA  +I +   +E+ID  L  + D         V ELAF+CL   ++ RPSM  V  +L++I   ++S W  +  DN
Sbjct:   46 SIPIFSYTELGQATNNFDSEKEVGDGGFGTVYYGKLQDGREVAVKRLYEHNYKRVKQFMNEIEILTRLHHKNLVCLYGCTSRRSRELLLVYEYIPNGTVADHLHGDQAKSSPLTWPIRMSIAIETASALAYLHAS---DIIHRDVKTNNILLDNNFSVKVADFGLSRLFPKDVTHVSTVPQGTPGYVDPEYHQSYQLTDKSDVYSFGVVLIELISSMPAVDITRHRHEINLSNLAISKIQKCAFDELIDSRLGYNSDEEVKRMTTSVAELAFQCLQQDKETRPSMENVLQQLKIIQGGEISNWKEARMDN 352          

Query:  646 GSQVCNPAKYLSG----QCGGKTRFIVL-----------IGASLMISLALICCFIRRQ--SKLKARLCTKRL-LSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWV-AIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG---LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            G+  C PA  LSG     C G   +  +           IG +L++ +  +  + RR+   + + RL  +R  +  A G+     +  K+I+KATN FS+ + LG G YG V+ G L D  V A+K  K       +QV+NE+R++  V H++LV LLGC +E  + ILVYE++ NG L   LQ  + DG   LSW  RL           +LH +  PPIYHRD+KSSNILLD    AK++DFGLSRL  ++ SHIST  QGT GYLDP+Y++ + L+DKSDVYSFGVVL+E++T  KA+DF RP++++NLA      +    L ++IDP+L+    +  L +V  +  LA  C+   R  RPSM EV  E+E I
Sbjct:  224 GNSTCGPAANLSGVRRCYCTGGLHWDPIQGICAHGLTSGIGLTLLVIVISVLLYKRRRRIKEAQERLAREREEILNAGGSRAAKIFTGKQIKKATNNFSKDRLLGAGGYGEVFKGILDDGTVVAVKCAKLGNTKGTDQVLNEVRILCQVNHRSLVCLLGCCVELQQPILVYEYIENGNLLDRLQGLKPDGKSQLSWLHRLQIAHDTADGLAYLHFSAVPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLAHSDLSHISTCAQGTLGYLDPEYYRKYQLTDKSDVYSFGVVLLELLTSQKALDFTRPEDDINLAVYVQRMMEEEKLMDVIDPMLKVKASSLHLETVKALAFLALSCIEEKRQNRPSMKEVAEEIEYI 599          

Query:  847 YPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQ-RERGDGL-SWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSED 1740
            + Y E+E+ATN F   + LG G +GTVY G L D   VA+KR+        EQ MNEI +++ +RH+NLV L GC+     E +LVYE+M NGT+  HL  R+   GL +WP+RL           +LH++    + HRD+K++NILLD +F  K+ADFGLSRL   + +H+STAPQGTPGY+DP+Y+Q + L+DKSDVYSFGVVL+E+I+ L+AVD  R ++++NL+ +A  +I    LNE++DP L    D      V  V ELAFRCL   R+MRP+M EV   L  I+   + +   D
Sbjct:  600 FSYNELEEATNCFDSSKELGDGGFGTVYYGVLRDGRVVAVKRLYESNMRRAEQFMNEIEILAHLRHKNLVELYGCTSRHSRELLLVYEYMPNGTVADHLHGRQSNSGLLTWPVRLSIAIETASALAYLHAS---DVIHRDVKTNNILLDNDFHVKVADFGLSRLFPTDVTHVSTAPQGTPGYVDPEYYQCYQLTDKSDVYSFGVVLIELISALEAVDTNRHRHDINLSIMAVKKIQNQALNELVDPFLGFDKDFVVRKMVTSVAELAFRCLQQQREMRPTMEEVLEILRRIEKENYGAEKAD 898          

Query:    4 GTDPIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-----SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHM-DAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            G  PI YPFGFS GCEI+LNCTP++G  IGEFPIQ+IT DSIR+ LQSRCNRPLHTL  LYS  YAPTSRNAILLQNCTDG+PSSSCEIPNILVQARFDA            YAE  KDV+FL+F  VE +DCKFLLSSISA  PQLLNSS               WWLEGTCGC KNANCTTVVSPNGT+G+ C C  G  GDGYVAG GC K S  CNPAKYLSG+CGGKTRFIVLIGA     SLMISLALICCFIRR SKLKAR  TKRLLSEATGNCNIPFY YKEIEKAT  FS+KQ LGTGAYGTVYAGKLHDEWVAIKRIKHRG++SI+QVMNEI+LISSVRH NLVRLLGCSIERGEQILVYEFM NGTLCQHLQRERG+GLSW  RL           HLHSA+KPPIYHRDIKSSNILLDC  K+K+ADFGLSRLGMAE+SHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDF RPQNEVNLAALATDRIGRGCLNEIIDP LEP + DAW L SVHKV ELAFRCLAF RDMRP+M+EVTAELELIKLS+WP SSE+NTYTA               KPLNI+KS+S RSV  LQSG AGS NS+E   K NSPVSV
Sbjct:   32 GPIPIQYPFGFSSGCEIQLNCTPNSGFAIGEFPIQSITQDSIRINLQSRCNRPLHTLLHLYSRNYAPTSRNAILLQNCTDGRPSSSCEIPNILVQARFDAPPNCSANSSLSCYAEARKDVQFLNFGSVEQKDCKFLLSSISAXSPQLLNSSTPLLLEVEVVELE--WWLEGTCGCDKNANCTTVVSPNGTEGYRCNCKEGFDGDGYVAGLGCRKVSSTCNPAKYLSGECGGKTRFIVLIGAVFVGASLMISLALICCFIRRXSKLKARHSTKRLLSEATGNCNIPFYSYKEIEKATXSFSDKQRLGTGAYGTVYAGKLHDEWVAIKRIKHRGHESIDQVMNEIKLISSVRHPNLVRLLGCSIERGEQILVYEFMGNGTLCQHLQRERGEGLSWLTRLTIAAETAKAISHLHSAVKPPIYHRDIKSSNILLDCKXKSKVADFGLSRLGMAETSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFTRPQNEVNLAALATDRIGRGCLNEIIDPFLEPLLDDAWXLSSVHKVAELAFRCLAFQRDMRPTMIEVTAELELIKLSKWP-SSEENTYTASSDGSSCCSSSSVSEKPLNITKSRSLRSVNALQSGDAGSFNSSEKF-KHNSPVSV 672          

Query:   16 IHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQSK-LKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSED----NTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSVH 1923
            + YPFGFS  C+IRLNC+ +  I +G+F +  +TP+++ V L + CNR   ++ +L+ P + PT  N++LLQNC+   P + C IP   VQ +F+              ++       + FE +    CK L  SIS      + S               GWW+ G C C  NA CT V     T G+ C+C +G  GDG+  GSGC + S+ CNP+KY+SG+CGG TR  VLIG     A +M  L  IC F+RR+S  L+ ++  +RLLSEA GN ++P YPYKEIE+ATN F+EKQ LGTGA+GTVYAGKLH DEWVAIK+I  R  + I+QVMNEI+L+SSV H NLVRLLGC IE GEQILVYE+M NGTL +HLQRERG GL W IRL           +LHS + PPIYHRDIKS+NILLD N+K+K+ADFGLSRLGM ESS++STAPQGTPGY+DPQYHQNFHLSD+SDVYSFGVVLVEIIT +K VDF RPQ++VNLAALA DRIG+G L+EI+DP LEP+ DAWTL SV+KVGELAFRCLAFH DMRPSM EV  ELE ++ S W +  E+    ++  +                    +  +S+RS++ L+     SL S E   KD+SPVSVH
Sbjct:   51 VRYPFGFSPSCQIRLNCSENNEIRLGKFRVLNVTPNAVFVNLPAICNRRFESVIELFGPNFGPTWNNSLLLQNCS--APQNGCLIPADFVQKQFNLESCRSSADNISCLSQPHNQSEVMRFEDLSRTGCKNLFGSIS------VQSDGESPLSLEFETVELGWWVGGLCDCDPNATCTRVKLGERTDGYQCRCVDGFDGDGFNHGSGCRRVSK-CNPSKYMSGRCGGTTRVGVLIGGVIAGAFIMAGLFFICHFVRRRSTCLRNQMSARRLLSEAAGNSSVPLYPYKEIERATNCFAEKQRLGTGAFGTVYAGKLHNDEWVAIKKINRRDTNGIDQVMNEIKLLSSVSHPNLVRLLGCCIEGGEQILVYEYMPNGTLSEHLQRERGQGLPWTIRLTIASETANAIAYLHSEMNPPIYHRDIKSNNILLDYNYKSKVADFGLSRLGMTESSYVSTAPQGTPGYVDPQYHQNFHLSDRSDVYSFGVVLVEIITAMKVVDFARPQSDVNLAALAIDRIGKGSLDEIVDPFLEPNRDAWTLYSVNKVGELAFRCLAFHSDMRPSMKEVAEELEYVRCSGWATMEENICMGSSVASSCSSPYNGSEKSSRGMTAKKAGIRSQRSIVSLR--VDSSLASMEE-DKDSSPVSVH 685          

Query:   16 IHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGT-QGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQSK-LKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSED----NTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSVH 1923
            + YPFGFS  C I LNC+    I +G+F +Q +TP+ I V L ++CNR + ++ +L+S  ++PT  N++LLQNC+   P + C IP   V+ +F+              ++       +    +    CK L  S +      + S               GWW+EG C C  NA CTTV    G  +G+ C+CN+G  GDG+  G GC + S+ C+P+KY+SG+CGG TR   LIG     A LM  L  +C F+RR+S  L+ R+  +RLLSEA GN N+  +PYKEI +ATN F+EKQ LGTGA+GTVYAGKLH DEWVAIK+I  R  +  +QVMNEI+L+SSV H NLVRL GC IE GEQILVYE+M NGTL +HLQRERG GL W IRL           +LHS + PPIYHRDIK +NILLD N+K+K+ADFGLS LGM ESS+ISTAPQGTPGY+DPQYHQNFHLSDKSDVYSFGVVLVEIIT +K VDF RPQ EVNLAALA DRIG+GC++EI+DP LEP  DAWTL SV+KV ELAFRCLAFH DMRPSM EV  ELE ++ S W +  E+    ++  + X                  +  +S+RS++ L+     SL S E   KD+SPVSVH
Sbjct:   51 VRYPFGFSPSCAIPLNCSDKNEITLGKFRVQNVTPNGIFVNLPAKCNRRVESVARLFSSNFSPTWNNSLLLQNCS--APQNGCIIPADFVRKQFNLESCRSSADNISCLSQXHNQSEXIRISDLTRTGCKNLFGSFA------VQSGGEWPLSLEFETVELGWWVEGPCDCDANATCTTVKLGXGMPEGYRCRCNDGFDGDGFNLGWGCRRVSE-CSPSKYMSGRCGGTTRVGALIGGVIAGAFLMAGLFXLCYFVRRRSTCLRNRMSARRLLSEAAGNSNVSLFPYKEIARATNCFAEKQRLGTGAFGTVYAGKLHNDEWVAIKKINRRDTNGXDQVMNEIKLLSSVSHPNLVRLXGCCIEGGEQILVYEYMPNGTLSEHLQRERGQGLPWTIRLTIASETANAIAYLHSEMNPPIYHRDIKXTNILLDYNYKSKVADFGLSXLGMTESSYISTAPQGTPGYVDPQYHQNFHLSDKSDVYSFGVVLVEIITAMKVVDFARPQCEVNLAALAIDRIGKGCVDEIVDPFLEPDRDAWTLYSVNKVAELAFRCLAFHSDMRPSMTEVAEELEFVRRSGWATMKENICMGSSVASSXSSPYNGSEKSFGGATAKKAGIRSQRSIVSLR--VDSSLASMEE-DKDSSPVSVH 686          

Query:  733 MISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHM-DAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQS 1857
            MISLALICCFIRRQSKLKAR  TKRLLSEATGNCNIPFY YKEIEKATN FS+KQ LGTGAYGTVYAGKLHDEWVAIKRIKHRG++SI+QVMNEI+LISSVRH NLVRLLGCSIERGEQILVYEFM NGTLCQHLQRERG+GLSW  RL           HLHSA+KPPIYHRDIKSSNILLDC FK+K+ADFGLSRLGMAE+SHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDF RPQNEVNLAALATDRIGRGCLNEIIDP LEP + DAW L SVHKV ELAFRCLAF RDMRP+M+EVTAELELIKLS+WP SSE+NTYTA               KPLNI+KS+S RSV  LQS
Sbjct:    1 MISLALICCFIRRQSKLKARHSTKRLLSEATGNCNIPFYSYKEIEKATNSFSDKQRLGTGAYGTVYAGKLHDEWVAIKRIKHRGHESIDQVMNEIKLISSVRHPNLVRLLGCSIERGEQILVYEFMGNGTLCQHLQRERGEGLSWLTRLTIAAETAKAISHLHSAVKPPIYHRDIKSSNILLDCKFKSKVADFGLSRLGMAETSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFTRPQNEVNLAALATDRIGRGCLNEIIDPFLEPLLDDAWPLSSVHKVAELAFRCLAFQRDMRPTMIEVTAELELIKLSKWP-SSEENTYTASSDGSSCCSSSSVSEKPLNITKSRSLRSVNALQS 375          

Query:   16 IHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGT-QGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQSK-LKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMME 1683
            + YPFGFS  C I LNC+    I +G+F +Q +TP+ I V L ++CNR + ++ +L+S  ++PT  N++LLQNC+   P + C IP   V+ +F+              ++       +    +    CK L  S +      + S               GWW+EG C C  NA CTTV   +G  +G+ C+CN+G  GDG+  G GC + S+ C+P+KY+SG+CGG TR   LIG     A LM  L ++C F+RR+S  L+ R+  +RLLSEA GN N+  +PYKEI +ATN F+EKQ LGTGA+GTVYAGKLH DEWVAIK+I  R  + ++QVMNEI+L+SSV H NLVRLLGC IE GEQILVYE+M NGTL +HLQRERG GL W IRL           +LHS + PPIYHRDIKS+NILLD N+K+K+ADFGLS LGM ESS+ISTAPQGTPGY+DPQYHQNFHLSDKSDVYSFGVVLVEIIT +K VDF RPQ EVNLAALA DRIG+GC++EI+DP LEP  DAWTL SV+KV ELAFRCLAFH DMRPSM E
Sbjct:   51 VRYPFGFSPSCAIPLNCSDKNEITLGKFRVQNVTPNGIFVNLPAKCNRRVESVARLFSSNFSPTWNNSLLLQNCS--APQNGCIIPADFVRKQFNLESCRSSADNISCLSQQHNQSEVIRISDLTRTGCKNLFGSFA------VQSGGEWPLSLEFETVELGWWVEGPCDCDANATCTTVKLGDGMPEGYRCRCNDGFDGDGFNLGWGCRRVSE-CSPSKYMSGRCGGTTRVGALIGGVIAGAFLMAGLFVLCYFVRRRSTCLRNRMSARRLLSEAAGNSNVSLFPYKEIARATNCFAEKQRLGTGAFGTVYAGKLHNDEWVAIKKINRRDTNGVDQVMNEIKLLSSVSHPNLVRLLGCCIEGGEQILVYEYMPNGTLSEHLQRERGQGLPWTIRLTIASETANAIAYLHSEMNPPIYHRDIKSTNILLDYNYKSKVADFGLSXLGMTESSYISTAPQGTPGYVDPQYHQNFHLSDKSDVYSFGVVLVEIITAMKVVDFARPQCEVNLAALAIDRIGKGCVDEIVDPFLEPDRDAWTLYSVNKVAELAFRCLAFHSDMRPSMTE 605          

Query:  733 MISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHM-DAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVS 1917
            MIS+AL+CCFIRR+SKLKAR  TKRLLS ATGNCNIPFY YKEIEKATN FS+KQ LG GAYGTVYAGKLHDEWVAIKRIKHRG++S++QVMNEI+LISSVRH NLV+LLGCSIE GEQILVYEFM NGTLCQHLQRERG+GLSW  RL           HLHSA  PPIYHRDIKSSNILLDC F++K+ADFGLSRLGM E+SHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVL EII+GLKAVDF RP +EVNLAALATDRIGR CLNEIIDP LEP M DAWTL SV KV ELAFRCLAFHRDMRP+M+EVTAELELIKLSRWP SSE+NTYTA               KPL+I+KS+S RSVI LQ+G AGS NS+E L +DNSPV+
Sbjct:    1 MISVALLCCFIRRRSKLKARHSTKRLLSAATGNCNIPFYSYKEIEKATNSFSDKQRLGNGAYGTVYAGKLHDEWVAIKRIKHRGHESMDQVMNEIKLISSVRHPNLVQLLGCSIEHGEQILVYEFMENGTLCQHLQRERGEGLSWLSRLNIAAETAQAISHLHSASNPPIYHRDIKSSNILLDCKFRSKVADFGLSRLGMVETSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLAEIISGLKAVDFNRPPDEVNLAALATDRIGRACLNEIIDPFLEPCMDDAWTLSSVQKVAELAFRCLAFHRDMRPTMIEVTAELELIKLSRWP-SSEENTYTASSEGSSHCSPSSVSEKPLSITKSRSLRSVIALQNGDAGSFNSSEKL-RDNSPVT 394          

Query:   13 PIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXX-GWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWK 645
            PI YPFGFS GCEIRLNC P+ GI IGEFPIQ+I  DSIR+ L+S CNRPLHTLR  YS +YAPTSRNAILLQNCT+G  S SCEIPN+LVQARFDA            YAET KDV FLDF  VE +DCKFLLSSISA PPQLLNSS               GWWLEGTCGC KNANCTTVVSPNGT+G+ C C  G LGDGYVAGSGCWK
Sbjct:   35 PIQYPFGFSSGCEIRLNCIPNGGIAIGEFPIQSINHDSIRINLKSHCNRPLHTLRNFYSRKYAPTSRNAILLQNCTEGTASGSCEIPNLLVQARFDAPPNCSSNSSLSCYAETRKDVPFLDFGSVERKDCKFLLSSISA-PPQLLNSSTPAAPVMLEVEVLDLGWWLEGTCGCDKNANCTTVVSPNGTEGYRCNCKEGFLGDGYVAGSGCWK 245          

Query:  718 IGASLMISLALICCFIR--RQSKLKARLCTKRL-LSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDS-IEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDG---LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELI 1707
            IGA+L+ +      + R  R  + +ARL  +R  +  A G      +   EI++ATN FS+ + LG G YG VY G L D  V   +I   GN   I+QV+NE+R++  V H++LV LLGC +E  + ILVYE++ NGTL +HLQ  +  G   LSW  RL           +LH +  PPIYHRD+KSSNILLD    AK++DFGLSRL   + SHIST  QGT GYLDP+Y++N+ L+DKSDVYSFGVVL+E++T  KA+DF R  ++VNLA  A   +    L +++DPLL+   +A  L ++  +G LA  CL   R  RPSM EVT E+E I
Sbjct:  299 IGATLIAATIAFLLYKRHRRIKEAQARLTKEREDILNANGGRAAKVFTGNEIKRATNSFSKDRLLGAGGYGEVYQGTLVDGTVVAVKIAKIGNTKGIDQVLNEVRILCQVNHKSLVHLLGCCVELEQPILVYEYIENGTLLEHLQARKPGGWKHLSWMQRLQIALDTAEGLAYLHFSAVPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLAHTDLSHISTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNREADDVNLAVYAQRMMLEERLMDVVDPLLKEGANALELDTMKALGLLALGCLEERRQNRPSMKEVTEEIEYI 635          

Query:  832 CNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGDG-LSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            C  P + Y E+++ATN F  +  LG G +GTVY GKL D   VA+KR+       +EQ +NEI +++ +RH+NLV L GC+  R  E +LVYE+++NGT+  HL  +R DG L+WPIR+           +LH++    I HRD+K++NILLD NF  K+ADFGLSRL   + +H+STAPQGTPGY+DP+YH+ + L+ KSDVYSFGVVL+E+I+ L AVD  R ++E+NLA LA  +I +G  NE++D  L    D      +  V ELAF+CL    ++RP+M EV   L++I+
Sbjct:  350 CGXPVFSYXELDEATNXFDSEXELGDGGFGTVYXGKLKDGREVAVKRLYEHNYKRVEQFINEIEILTRLRHRNLVSLYGCTSRRSRELLLVYEYISNGTVADHLHGDRADGSLTWPIRMSIAIETADALSYLHAS---EIVHRDVKTNNILLDDNFCVKVADFGLSRLFPXDVTHVSTAPQGTPGYVDPEYHECYQLTSKSDVYSFGVVLIELISSLPAVDIMRHRHEINLANLAISKIQKGLFNELVDQRLGFESDGEVRRMIIAVAELAFQCLQQDNNVRPTMNEVLEALKMIE 642          

Query:  637 CWKGSQVCNPAKYLSGQCGGKTRFIVLIGASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERG-EQILVYEFMANGTLCQHLQRERGD--GLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIK 1710
            C KG +  N    L    G      + +   L+        F+ R   + ++  T   +      C  P + Y E+++ATN F  +  LG G +GTVY GKL D   VA+KR+       +EQ +NEI +++ +RH+NLV L GC+  R  E +LVYE+++NGT+  HL  +R D   L+WPIR+           +LH++    I HRD+K++NILLD NF  K+ADFGLSRL   + +H+STAPQGTPGY+DP+YH+ + L+ KSDVYSFGVVL+E+I+ L AVD  R ++E+NLA LA  +I +G  NE++D  L    D      +  V ELAF+CL    ++RP+M EV   L++I+
Sbjct:  261 CTKGDKQLNLKLGLGIGLGFPALLAICVXLLLLYKXKXSSLFLSRN--ISSQPXTNSDIEXGGAYCGXPVFSYXELDEATNXFDSEXELGDGGFGTVYXGKLKDGREVAVKRLYEHNYKRVEQFINEIEILTRLRHRNLVSLYGCTSRRSRELLLVYEYISNGTVADHLHGDRADPGSLTWPIRMSIAIETADALSYLHAS---EIVHRDVKTNNILLDDNFCVKVADFGLSRLFPXDVTHVSTAPQGTPGYVDPEYHECYQLTSKSDVYSFGVVLIELISSLPAVDIMRHRHEINLANLAISKIQKGLFNELVDQRLGFESDGEVRRMIIAVAELAFQCLQQDNNVRPTMNEVLEALKMIE 617          

Query:   22 YPF-GFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLN--ISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            +PF G S  C+IRLNC+    I +GEFP+++I P+SI V L+ RCNR + +L  L++  YAPT+RN ILL++C    P+S+C IP   V   F++            Y+E  ++  FL    V    C++LLSSIS       N+S+             GWWL G C CH+ A CT + +P  G QGF CKC +G  GDGY AG GC K S  CNP++Y+SGQCGG +RF VL G  +LMIS++ ICCF+RR    KAR  T+R LSEATG C+IP YPY+ IEKAT+ FSEKQ LGTGAYGTVY+GKLH++WVAIKRIKHR  DSIE+V+NEI+LISSV H NLVRLLGCSIE+GEQILVYEFMANGTL QHLQRERG+GL W +RL           HLHSA+ PPIYHRDIKSSNILLD NF  KLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIIT LK VDF RPQNEVNLAALA DRIG+G L+EIIDP LEPH DAW+L S+HKV ELAFRCLAFHRDMRPSMMEV AELE IKL +W ++SEDN  TA                PL+  + K       + +      S+NS   L KD SPVSV
Sbjct:  103 FPFIGTSSACQIRLNCSTDGDIMVGEFPVRSIFPESILVNLEVRCNRSIKSLDHLFNTNYAPTTRNGILLKHCKS--PASTCTIPTTKVNTHFESIDCGSDNYSISCYSEEHEN-GFLSQANVSKSHCQYLLSSISVDA---FNTSSVVLDVGIVQL---GWWLLGECKCHQEATCTEIQTPVAGQQGFRCKCRDGFDGDGYQAGVGCRKASSGCNPSRYISGQCGGPSRFFVLAGGIALMISISAICCFMRRCLTSKARNSTRRRLSEATGKCSIPIYPYRAIEKATSSFSEKQRLGTGAYGTVYSGKLHNQWVAIKRIKHRDTDSIEEVLNEIKLISSVSHPNLVRLLGCSIEKGEQILVYEFMANGTLSQHLQRERGNGLVWAVRLSIATQTAQAIAHLHSALNPPIYHRDIKSSNILLDHNFIPKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITALKVVDFSRPQNEVNLAALAIDRIGKGRLDEIIDPFLEPHRDAWSLSSLHKVAELAFRCLAFHRDMRPSMMEVAAELEQIKLCKW-ATSEDNMCTASSETSSCSSSSNVSEIPLSMTVEKGGLGSEGLFVLPTKVISMNSLGRL-KDTSPVSV 729          

Query:   22 YPF-GFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLN--ISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            +PF G S  C+IRLNC+    I +GEFP+++I P+SI V L+ RCNR + +L  L++  YAPT+RN ILL++C    P+S+C IP   V   F++            Y+E  ++  FL    V    C++LLSSIS       N+S+             GWWL G C CH+ A CT + +P  G QGF CKC +G  GDGY AG GC K S  CNP++Y+SGQCGG +RF VL G  +LMIS++ ICCF+RR    KAR  T+R LSEATG C+IP YPY+ IEKAT+ FSEKQ LGTGAYGTVY+GKLH++WVAIKRIKHR  DSIE+V+NEI+LISSV H NLVRLLGCSIE+GEQILVYEFMANGTL QHLQRERG+GL W +RL           HLHSA+ PPIYHRDIKSSNILLD NF  KLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIIT LK VDF RPQNEVNLAALA DRIG+G L+EIIDP LEPH DAW+L S+HKV ELAFRCLAFHRDMRPSMMEV AELE IKL +W ++SEDN  TA                PL+  + K       + +      S+NS   L KD SPVSV
Sbjct:   43 FPFIGTSSACQIRLNCSTDGDIMVGEFPVRSIFPESILVNLEVRCNRSIKSLDHLFNTNYAPTTRNGILLKHCKS--PASTCTIPTTKVNTHFESIDCGSDNYSISCYSEEHEN-GFLSQANVSKSHCQYLLSSISVDA---FNTSSVVLDVGIVQL---GWWLLGECKCHQEATCTEIQTPVAGQQGFRCKCRDGFDGDGYQAGVGCRKASSGCNPSRYISGQCGGPSRFFVLAGGIALMISISAICCFMRRCLTSKARNSTRRRLSEATGKCSIPIYPYRAIEKATSSFSEKQRLGTGAYGTVYSGKLHNQWVAIKRIKHRDTDSIEEVLNEIKLISSVSHPNLVRLLGCSIEKGEQILVYEFMANGTLSQHLQRERGNGLVWAVRLSIATQTAQAIAHLHSALNPPIYHRDIKSSNILLDHNFIPKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITALKVVDFSRPQNEVNLAALAIDRIGKGRLDEIIDPFLEPHRDAWSLSSLHKVAELAFRCLAFHRDMRPSMMEVAAELEQIKLCKW-ATSEDNMCTASSETSSCSSSSNVSEIPLSMTVEKGGLGSEGLFVLPTKVISMNSLGRL-KDTSPVSV 669          

Query:    4 GTDPIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQV-------CNPAKYLSGQCGGKTRFIVLIG---ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSE---RSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            GT+ + YPFGFS  C+I LNC+PH  + I EFP+Q +  +SI++ L+ +CNRPL  L  L++  YAP S NAILL NCT     S C IP+I VQ  F++              E   +  F D+       C++ LSSISA       S                WWL+G C C K+A CT V SP G+ GF C+C +GL+GDGY+AG GC KGS +       CNPAKYLSGQCGG +   VL+G   A + +SL L CC +RR S  KA+   K  LSEA  + NIP YPYKEIEKATN FSEKQ +GTGAYGTVYAGKL+ D WVAIKRIKH   D+IEQVMNEI+LISSV H NLVRLLGCSIE GEQILVYEFM NGTLCQHLQRERGDGL WP+RL           HLHSA+ PPIYHRDIKSSNILLD +F++K+ADFGLSR GM E SHIST PQGTPGYLDPQYH NFHLSDKSDVYSFGVVLVEIIT  K VDF RPQNEVNLAALATDRIGRG L+EIIDP L+ H DAWT  SVHKV E+AFRCLAFH+DMRPSMMEV AELE I LSRW SS E N                   KPLN +  ++E   R + +LQ+    S  STE     NSPVSV
Sbjct:   34 GTNHLPYPFGFSADCDIHLNCSPHGEMLINEFPVQIVGQNSIKIILEPKCNRPLEALDNLFTKNYAPKSTNAILLHNCTSAV--SPCNIPSINVQTHFESLKCSNNSSLSCFSKEVTAN-GFFDYNMANISQCQYFLSSISAE------SFTGSGVSLEIQMMELWWWLQGDCRCSKDAICTQVESPAGS-GFRCQCRDGLIGDGYLAGVGCRKGSFLDVKASAGCNPAKYLSGQCGGGSGAAVLLGGVVAGVGVSLGLFCCLVRRNSASKAKSFRKLHLSEAA-DINIPIYPYKEIEKATNSFSEKQRIGTGAYGTVYAGKLNSDSWVAIKRIKHGDMDNIEQVMNEIKLISSVSHPNLVRLLGCSIENGEQILVYEFMPNGTLCQHLQRERGDGLDWPVRLAIAADTAKAIAHLHSAMDPPIYHRDIKSSNILLDYHFRSKVADFGLSRHGMTEISHISTVPQGTPGYLDPQYHLNFHLSDKSDVYSFGVVLVEIITAKKVVDFSRPQNEVNLAALATDRIGRGRLDEIIDPFLDLHSDAWTFSSVHKVAEVAFRCLAFHKDMRPSMMEVAAELEQILLSRWASSEETNC-AISLDFSPCSSSSNVSDKPLNSTVKKTEIERRGLFVLQTQT--SKKSTER-ANHNSPVSV 671          

Query:   13 PIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXX--YAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGT-CGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-----SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHD-EWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHM--DAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISK---SQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            P+ YPFGFS GC IRL CT      +GEFP++  T DS+ V+++++CNRP  +L  L+S +YAPTSRN ILL+NCT G P   C IP  LV+  F++              Y E   +  F+D   ++   CK+ +SS++A  P + N S              GWWL+G  C C  +ANCTT+ SP +G  GF C+C +G +GDG++AG+GC K S  CNPAKY+SG+CGG TRFIVLIG      SLM++L  +CCF RR+SKL+    TKR L+EATG  ++P YPYK+IEKATN FSEKQ LGTGAYGTVYAGKL++ EWVAIKRIKHR  DSIEQVMNEI+L+SSV H NLVRLLGCSIE GEQILVYEFM NGTL QHLQ+ERG GL WPIRL           +LHSAI PPIYHRDIKSSNILLD NF++K+ADFGLSRLGM E SHIST PQGTPGY+DPQYHQ+FHLSDKSDVYS GVVLVEIITGLK VDF RP NEVNLA+LA D+IG+G LNEIIDP LEP +  DAWTL S+HKV ELAFRC+AFHRDMRPSM EV +ELE ++LSRW +  ++N  T+               KPL+I+        +  + LQ+G   +L S +     NSPVSV
Sbjct:   47 PVPYPFGFSSGCAIRLKCTAGVAS-VGEFPVKVNT-DSMIVSIEAQCNRPFDSLHHLFSHKYAPTSRNVILLENCT-GTPLP-CFIPETLVRTHFESVGCNNASGTGELSCYFENRTN-GFVDRRTLDEIGCKYFMSSLAA--PDIKNISGAPLSLDVNIIQL-GWWLQGDQCLCSDHANCTTLQSPMDGKPGFRCRCRDGFVGDGFLAGTGCRKASS-CNPAKYISGRCGGTTRFIVLIGGFVVGVSLMVTLGSLCCFYRRRSKLRVTNSTKRRLTEATGKNSVPIYPYKDIEKATNSFSEKQRLGTGAYGTVYAGKLYNNEWVAIKRIKHRDTDSIEQVMNEIKLLSSVSHTNLVRLLGCSIEYGEQILVYEFMPNGTLSQHLQKERGSGLPWPIRLTIATETAQAIAYLHSAICPPIYHRDIKSSNILLDYNFRSKVADFGLSRLGMTEISHISTTPQGTPGYVDPQYHQDFHLSDKSDVYSLGVVLVEIITGLKVVDFSRPHNEVNLASLAADKIGKGLLNEIIDPFLEPEVRSDAWTLSSIHKVAELAFRCIAFHRDMRPSMTEVASELEQLRLSRWTTLGDNNCATS-TELSSCSSSSNECEKPLSIATRNFGAKGKGHLKLQTGPI-NLKSLQR-PNSNSPVSV 685          

Query:   13 PIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVR-FLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGT-CGCHKNANCTTVVSP-NGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGA-----SLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLL--EPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTA 1755
            P+ YPFGFS GC IRLNCT      +GEFP++  T DS+ V+++++CNR   +   L+S +YAPTSRN ILL NCT       C IP  LV+  F++                 K    F+D   ++   CK+ +SS+S   P + N S              GWWL+G  C C  +ANCTT+ SP +   GF C+C +G +GDG++ G+GC K S  CNPAKY+SG+CGG TRFIVLIG      SLM++L  +CCF RR+SKL+    TKR L+EATGN ++P YPYK+IEKATN FSEKQ LGTGAYGTVYAGKL+ DEWVAIKRIKHR  DSIEQVMNEI+L+SSV H NLVRLLGCSIE GEQILVYEFM NGT  QHLQ+ERG GL WP+RL           HLHSAI PPIYHRDIKSSNILLD NF++K+ADFGLSRLGM E SHISTAPQGTPGY+DPQYHQ+FHLSDKSDVYS GVVLVEIITG K VDF RP NEVNLA+LA DRIG+G LNEIIDP L  E   DAWTL S+HKV ELAFRCLAFHRDMRPSM EV +ELE + LSRW +  ++N  T+
Sbjct:   48 PVPYPFGFSSGCAIRLNCTAGVAS-VGEFPVKVNT-DSLIVSIEAQCNRSFDSFHHLFSHKYAPTSRNVILLDNCT--ATPLPCSIPETLVRTHFESVGCGNASGTGELSCYFEKITNGFMDQRMLDEIRCKYFMSSLSV--PDIKNISGTAPLSLGVNVIELGWWLQGDRCLCSDHANCTTLQSPVDRKPGFRCRCRDGFVGDGFLVGTGCQKASS-CNPAKYMSGRCGGTTRFIVLIGGFVIGVSLMVTLGSLCCFYRRRSKLRVTKSTKRRLTEATGNNSVPIYPYKDIEKATNSFSEKQRLGTGAYGTVYAGKLYNDEWVAIKRIKHRDTDSIEQVMNEIKLLSSVSHTNLVRLLGCSIEYGEQILVYEFMPNGTRSQHLQKERGSGLPWPVRLTIATETAQAIAHLHSAICPPIYHRDIKSSNILLDYNFRSKVADFGLSRLGMTEISHISTAPQGTPGYVDPQYHQDFHLSDKSDVYSLGVVLVEIITGQKVVDFSRPHNEVNLASLAADRIGKGLLNEIIDPFLEAEARSDAWTLSSIHKVAELAFRCLAFHRDMRPSMTEVASELEQLSLSRWTTMGDNNCATS 632          

Query:    4 GTDPIHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG---ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSE---RSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            GT  + YPFGFS  C+I LNC+ +  + I +FP+Q +  D+I++ L+ RC RP+  L  L +  YAP S NAILL NCT G   S C IP+I V+  F++            +++      F D+       CK+LLSSISA       S                WWL+G C C K+A CT V SP G+ GF C+C +GL+GDGY+AG GC K +  CNPAKYLSGQCG   R  VL+G   A++ + L L CC  RR S  KA+   K   +EA  + +IP YPYKEIEKATN FSEKQ +GTGAYGTVYAGKL  D WVAIKRIKHR  DSIEQV+NEI+LISSV H NLVRLLGCSIE  EQILVYEFM NGTLCQHLQR RGDGL WP+RL           HLHSAI PPIYHRDIKSSNILLD +FK+K+ADFGLSR GM + SHIST PQGTPGYLDPQYHQNFHLSDK+DVYSFGVVL+EIIT  K +DF RPQ+EVNLA+LA D+IGRG L+EIIDP L+ H DAWT  SVHKV ELAFRCLAFH+D+RPSMMEV AELE I L+RWP S E N  T                K LN++  ++E   R +++LQ+ A  S  STE     NSP+SV
Sbjct:   34 GTSHLPYPFGFSANCDIHLNCSLNGEMLINDFPVQIVGQDTIKINLEPRCYRPVEALYNLSTKNYAPKSTNAILLNNCTSG--FSPCNIPSISVRTHFESLNCSNNSSVSC-FSKADTANGFFDYNMANISQCKYLLSSISAE------SFTGSGVSLETQMMELWWWLQGDCQCSKDAICTKVESPAGS-GFRCQCRDGLIGDGYLAGVGCRKAAG-CNPAKYLSGQCGAGARPAVLLGGIVAAVGVGLGLFCCLTRRNSISKAKSFRKLHRAEAA-DISIPIYPYKEIEKATNSFSEKQRIGTGAYGTVYAGKLSSDSWVAIKRIKHRDVDSIEQVINEIKLISSVSHPNLVRLLGCSIENDEQILVYEFMPNGTLCQHLQRVRGDGLDWPVRLAIATETAKAIAHLHSAIDPPIYHRDIKSSNILLDFDFKSKVADFGLSRHGMTDMSHISTVPQGTPGYLDPQYHQNFHLSDKTDVYSFGVVLIEIITAKKVLDFSRPQDEVNLASLAIDKIGRGLLDEIIDPFLDLHNDAWTFSSVHKVAELAFRCLAFHKDIRPSMMEVAAELEQIMLTRWPPSEEINC-TTSLDFSQCSSSSHVSEKALNLTVKKTEIERRGLLVLQTQA--SRKSTER-TDHNSPMSV 663          

Query:   16 IHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTC-----GCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQS-KLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPL---NISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            + YPFGFS GCEI+LNC   TG I IGEF +Q ITP+ I V+L ++CNR L  +  L+   YAP  RN +LLQNCT  +  SSC IP      +               Y+     +  L +  +    CKFL SS +         S               WWL+G+C      C K+ANCT +   +G  GF C C  G  GDG+  G GC +    CN +KY++GQCGG TR  VL+G     ASLM  LALI  F+R++S  L+ RL  KRLL EA GN ++PFYPY+EIEKATNGFSEKQ LG GAYGTVYAGKLH +EWVAIK+I+HR  DSI+QVMNEI+L+SSV H NLVRLLGC IE GE ILVYEFM +GTLCQHLQRERG GL W IRL           +LHSA+ PPIYHRDIKSSNILLD N+K+K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQ FHLSDKSDVYSFGVVLVEIITGLK VDF RP +EVNLAALA DRIGRGC++EIIDP L+P+ DAWTL S+H V ELAFRCLAFHRDMRP+MMEV  ELE I+LS W      N Y A               + L   +I K+      +L+    A  L S E + KD+SPVSV
Sbjct:   44 VSYPFGFSDGCEIQLNCRQDTGDIGIGEFVVQNITPNGILVSLPAKCNRSLEAISPLFGDHYAPAWRNGLLLQNCT--RTLSSCYIPTSSFANQLHIPSCNPRSDNITCYSRERLGMDVLSYNNLNSAGCKFLFSSFAVG-------SNNPSVSLEFERVELDWWLDGSCKLNRSNCSKHANCTDIKLGDGKGGFRCWCQEGFTGDGFRNGDGC-RSVSGCNASKYINGQCGGTTRVGVLVGGIIAGASLMAGLALIWYFVRQRSTSLRNRLSAKRLLCEAAGNSSVPFYPYREIEKATNGFSEKQRLGIGAYGTVYAGKLHNEEWVAIKKIRHRDTDSIDQVMNEIKLLSSVSHPNLVRLLGCCIEEGEPILVYEFMPHGTLCQHLQRERGKGLPWTIRLTIAAETANAIAYLHSAMNPPIYHRDIKSSNILLDYNYKSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQYFHLSDKSDVYSFGVVLVEIITGLKVVDFSRPHSEVNLAALAIDRIGRGCVDEIIDPYLDPNRDAWTLSSIHNVAELAFRCLAFHRDMRPTMMEVAEELEHIRLSAW----VPNMYMASPAASSCSSPDNGSERSLGVHSIKKAGVVSRRLLVPQRPADCLTSLEEI-KDSSPVSV 679          

Query:   16 IHYPFGFSHGCEIRLNCTPHTGIFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALICCFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPL---NISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSVH 1923
            +HYPFGFS    I+LNC+    I I  F +Q +T DSI + L ++C R +  +  L+   YA +S+N++L QNC+    SS C IP  +   +                     +  F+ F  V    CKFLL S++    +  N+SA             GWWL+  C C  NA  T +  P G  G  C C  G  GDG+  G GC + +  CN +KY+SG CGG TR  VL+G     ASLM ++ALIC  IRR+S L+ R+  KRL+ EA GN ++P YPYKE+E+ATNGFSEKQ LGTGAYGTV+AGKLH DEWVAIK+I++R NDSIEQVMNEI+LISSV H NLVRLLGC IE GEQILVYEFMANGTL QHLQ+ERG GL W  RL           HLHSAI PPI+HRDIKSSNILLD NF +K+ADFGLSRLGM ESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEII+ +K VDF RP +EVNLAALA DRIGRGC++EIIDP LEP  DAWTL S+HKV ELAFRCLAFHRDMRPSMMEV  ELE ++LS W +  E+N   A                 L   ++ K+      + +       L S E + KD+SPVSVH
Sbjct:   46 VHYPFGFSSDSPIKLNCSKEGEIEIQNFKVQNVTTDSIIINLPAQCQREIQKIEPLFGKNYALSSKNSLLFQNCSSS--SSGCVIPTSVFNGQNKLNNCNGKSDNNISCFPLDSESEFMSFANVTGTGCKFLLLSMAV---EWRNNSAVSLELGTAQL---GWWLDHPCHCAPNAKHTNLTVPGGF-GCRCSCKEGFDGDGFKDGDGCQEVTD-CNASKYMSGTCGGTTRVAVLVGGVIVGASLMSTVALICYCIRRRSYLRRRMSAKRLICEAAGNSSVPLYPYKEVERATNGFSEKQRLGTGAYGTVFAGKLHNDEWVAIKKIRNRDNDSIEQVMNEIKLISSVNHPNLVRLLGCCIENGEQILVYEFMANGTLSQHLQKERGKGLPWTTRLNIATETANAIAHLHSAITPPIFHRDIKSSNILLDDNFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIISAMKVVDFSRPHSEVNLAALAIDRIGRGCVDEIIDPFLEPQRDAWTLCSIHKVAELAFRCLAFHRDMRPSMMEVADELEHVRLSGW-APMEENICVASSVASSCSSPFNGSEMSLGCMSVRKAGIGSRRLFVPHRPTDCLASMEEI-KDSSPVSVH 678          

Query:   16 IHYPFGFSHGCEIRLNCTPHTG-IFIGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKVEHRDCKFLLSSISASPPQ-LLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIG-----ASLMISLALIC-CFIRRQSKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLH-DEWVAIKRIKHRGNDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPS 1728
            + YPFGFS GC IRL+CT  TG I IGE+ IQ +T +++ V     C+RP+  L+Q     +  T RN +LL NC    P S C IP+ ++  R +             Y+E   D  +LD++K+++  C  ++SSI        + SSA              W LEG C CH +ANCT V  P   +GF C+C +G +GDG+  G GC K S+ CNP++YLSG+CGG TR  VL+G     A LM +LA++C C  RR + LK R+  +RLLSEA G+ ++  + YKEIE+ATN FSEKQ LG GAYGTVYAGKLH DEWVAIK+++HR  D +EQVMNE++L+SSV H NLVRLLGC IE GEQILVYEFM NGTL QHLQRER  GL W IRL           HLHSA+ PPIYHRDIKSSNILLD NF +K+ADFGLSR GM + SHISTAPQGTPGY+DPQYHQN+HLSDKSDVYSFGVVLVEIIT +K VDF R  +E+NLAALA DRIG+G ++EIIDP LEPH DAWTL SVH+V ELAFRCLAFHRDMRPSM EV  ELE I+LS W S
Sbjct:   46 VSYPFGFSEGCGIRLDCTESTGEIRIGEYIIQNVTSETLMVNFSMNCSRPIEDLQQFDRTNFGMTWRNGLLLHNCK--VPKSECTIPSEILSTRLNIQSCDSKKENVSCYSEARAD--YLDYQKLKNTGCGTVISSILIGMDNDTMKSSAMFIEFQTMEL---AWGLEGDCACHNDANCTNVSLPGNRKGFRCRCKDGFVGDGFSDGDGCRKVSR-CNPSRYLSGRCGGTTRIGVLVGGIIAGAGLMAALAVLCYCIRRRSASLKKRMSARRLLSEAAGSNSVHVFQYKEIERATNSFSEKQRLGIGAYGTVYAGKLHSDEWVAIKKLRHRDPDGVEQVMNEVKLLSSVSHPNLVRLLGCCIENGEQILVYEFMPNGTLAQHLQRERSSGLPWTIRLTIATETAHAIAHLHSAMNPPIYHRDIKSSNILLDYNFNSKVADFGLSRFGMTDDSHISTAPQGTPGYVDPQYHQNYHLSDKSDVYSFGVVLVEIITAMKVVDFSRSHSEINLAALAIDRIGKGRVDEIIDPFLEPHRDAWTLSSVHRVAELAFRCLAFHRDMRPSMTEVADELEQIRLSSWAS 617          

Query:   88 IGEFPIQTITPDSIRVTLQSRCNRPLHTLRQLYSPRYAPTSRNAILLQNCTDGQPSSSCEIPNILVQARFDAXXXXXXXXXXXXYAETGKDVRFLDFEKV--EHRDCKFLLSSISASPPQLLNSSAXXXXXXXXXXXXXGWWLEGTCGCHKNANCTTVVSPNGTQGFTCKCNNGLLGDGYVAGSGCWKGSQVCNPAKYLSGQCGGKTRFIVLIGAS-LMISLALICCFIRRQ-SKLKARLCTKRLLSEATGNCNIPFYPYKEIEKATNGFSEKQGLGTGAYGTVYAGKLHDE-WVAIKRIKHRG-NDSIEQVMNEIRLISSVRHQNLVRLLGCSIERGEQILVYEFMANGTLCQHLQRERGDGLSWPIRLXXXXXXXXXXXHLHSAIKPPIYHRDIKSSNILLDCNFKAKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITGLKAVDFKRPQNEVNLAALATDRIGRGCLNEIIDPLLEPHMDAWTLLSVHKVGELAFRCLAFHRDMRPSMMEVTAELELIKLSRWPSSSEDNTYTAXXXXXXXXXXXXXXXKPLNISKSQSERSVILLQSGAAGSLNSTETLKKDNSPVSV 1920
            + EFPI  +  + IR+ L+ +C+RP+ T + L++  +AP S NAILL NC+       C IP+I VQ  F++                     F D  K   + + C + LSSIS+   + +N S              GWWL G C C + A+C  + SP G  G+ C+C +G  GDGY AG+GC KGS  CN  K+LSGQCG   R  VLIG S LM++L L+CCFIRR+ S  KA+   K  LSEATG  NIP YPYKEIEKATN FS+KQ LGTGAYGTVYAGKLH++ WVAIKRIKHR  +DS+EQVMNEI+LISSV H +LVRLLGCSIE GEQ+LVYEFM NGTLCQHLQRE+GDGL+WP+RL           +LHSAI PPIYHRDIKSSNILLD NF++K+ADFGLSRLG  E SHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVL+EIIT LK VDF R  NEVNLAALATDRIG+G L EIIDPLL+ H DAWT  +VHKV ELAFRCLAF +D RPSMMEV AELE +++SRW    E     +               KPL+ + +  E   I L +    S+ ST+   KD+SPVSV
Sbjct:    3 VNEFPIVYVNQEKIRIDLRPKCDRPIDTFKSLFTKNFAPMSTNAILLNNCSS--TLLPCSIPDISVQTHFESLNCSKSSRSSISCLFNLTRDNFFDSGKYTDQLKYCDYFLSSISS---ESVNGSGVSLDILVLDL---GWWLPGKCQCSEQADCIKIASPKGP-GYRCRCKDGFSGDGYSAGTGCRKGS--CNLEKHLSGQCGETIRIAVLIGGSALMVALGLVCCFIRRRFSTSKAKGFRKLSLSEATG-INIPIYPYKEIEKATNSFSDKQRLGTGAYGTVYAGKLHNDIWVAIKRIKHRDIDDSVEQVMNEIKLISSVNHPSLVRLLGCSIENGEQVLVYEFMPNGTLCQHLQREKGDGLAWPVRLTIAAETAQAIAYLHSAIDPPIYHRDIKSSNILLDYNFRSKVADFGLSRLGRTEISHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLIEIITALKVVDFSRQYNEVNLAALATDRIGKGRLAEIIDPLLDIHCDAWTFSTVHKVAELAFRCLAFDKDTRPSMMEVAAELEQLRISRWSPEEEIKFRASSVESSCSTSSSNISEKPLSSTNNNGELGNISLFT-QVRSVKSTDE-AKDDSPVSV 605