ppa025090m, ppa025090m (mRNA) Prunus persica

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR--FGQRRCLCKAGFQWDAINAICHSL---------------------VFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTE---SSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIV 1839
            ME  V  LL+  +A+L CT   A     C DCG + VPYPLST P CG+Q YKVRCNAG LW D L+ SSY+ITSINP T+R+I++P  L  N TC+  D +  G+ LD   P+NI S NT++ MNCSN +L  S NCS NS+CH Y++ N +AA ACR    CC +K GG  NAYKI VR E C AY SFVNL TS   +  WPEPG+EI W LP EP CK+P DC  L+NS+CL D    GQRRC CKAGF W  IN +C +L                     V    A+LI   +G +V + R QN+ R A  SL K REDMLNANNS GK AKIF+GKEI RATNNFSKDN +GSGGF EVFKG+LDDGT+TAVKRAK GNTKG DQ+ NEVRILCQVNHR LV+L+GCC+ELEQP++IYEYI NGTLF+HLH    ++ K  +LTW  RL+IA QTAEGLAYLH S VP IYH D+KSSNILLD+KL+AKV+DFGLSRLA+     +SHITTCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLELLTSKK IDFNR+EEDVNLV+Y+K I++EE+LMD IDP +KDGA  V++E++KALG LA+ACLDERRQ+RPSMKE A+EIEYIISI+
Sbjct:    1 MEKNVLPLLLHALALLLCT-RAAMCAPRCGDCGRIPVPYPLSTGPGCGDQSYKVRCNAGTLWFDALSQSSYVITSINPGTRRMIVKPASLLAN-TCITTDIQVGGLQLDRISPYNIPSSNTIMLMNCSNAVLNSSVNCSPNSICHAYIRENVVAA-ACRSTAKCCWFKAGGPVNAYKIGVRDEGCMAYQSFVNLATSL-PVKRWPEPGLEIEWALPQEPICKIPKDCSTLLNSMCLPDGAILGQRRCFCKAGFHWGPINGLCQNLKCEKAKSCKHKKKSRTPLLGGVAVVAAILILVPVGILVCRHR-QNLKREAQGSLIKKREDMLNANNS-GKMAKIFSGKEIKRATNNFSKDNFIGSGGFSEVFKGILDDGTVTAVKRAKLGNTKGTDQVLNEVRILCQVNHRCLVRLLGCCVELEQPIMIYEYIPNGTLFDHLH--GHHSRKWPALTWRRRLSIALQTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKLDAKVSDFGLSRLAVVSEANASHITTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVLYIKKIMKEEKLMDVIDPVLKDGASKVDMESVKALGLLAAACLDERRQSRPSMKEAAEEIEYIISII 631          

Query:   19 SLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAICHS---------------------LVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQV 1851
            +LL+ T A+L C    A     CPDCG+  VPYPLST  DCG+Q+YK+RC+AG L  DTLNSS Y I+SI P  QR +IRP   A N TC+  D  +QGI L+ +LPFN++S NT++ +NC++ +L    NCSS SLCH Y+ +    A+AC   P+CC +K GGS  ++ IRVR   C AY SFVNLD S+  ++ WPEPGVEI W  P EP C    DC D MNS C  D    G  RC CK+G  WD +  +C                       L     A LI A+I  +VY+R  +   + A   L + RE++LNAN   GK AK FTGKEI RATN+FS D +LG+GG+GEV+KG+LDDGTI A+K AK GN KG DQ+ NEV ILCQVNHRSLV+L+GCC+ELEQP+++YE+I NGTL EHL         R SLTW  RL IA  TAEGLAYLH S VP IYH D+KSSNILLD+K+NAKVADFGLSRLA T+ SH++TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDFNR  +DVNL VYV+  + EERLMDAIDP +K+ A  +ELETMKA+G LA  CL+ERRQNRPSMKEV +EI YIISI T +V
Sbjct:    3 NLLLFTAALLLCAV-CAMAANRCPDCGNTSVPYPLSTGADCGDQEYKIRCDAGTLRFDTLNSS-YSISSITPQIQRFVIRPASFAGN-TCVTTDLPNQGIQLNESLPFNVTSSNTILYLNCTDTLLRSPLNCSSISLCHTYI-NGTRDAAACEDAPICCTFKAGGSTTSHSIRVRDAGCRAYRSFVNLDAST-PVNRWPEPGVEIQWVSPREPVCTSQSDCTDGMNSTCGPDPATAGVSRCFCKSGLWWDPVGGLCAQNVTCQDPDGCGSTNKTPLIAGLTVGIGAALIAAVIAILVYRRHRR--IKEAQDRLAREREEILNANGG-GKFAKNFTGKEIKRATNSFSHDRLLGAGGYGEVYKGILDDGTIVAIKCAKLGNAKGTDQVLNEVGILCQVNHRSLVRLLGCCVELEQPIMVYEFIPNGTLLEHLQ--GQRPGGRGSLTWSHRLRIAHDTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKMNAKVADFGLSRLAHTDMSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNRPADDVNLAVYVQRTVEEERLMDAIDPLLKEQASSLELETMKAMGFLAVGCLEERRQNRPSMKEVTEEIGYIISIATAKV 626          

Query:   22 LLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGV--LWLDTLNSSSYLITSINPLTQRLIIRP-PGLANNVTCMAADFK-SQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHN-----PMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCL-ADRFGQRRCLCKAGFQWDAINAIC-----HSLVFAAVAMLIGAI-IGSVVYKRRDQNVARSAHFS----LTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELET-MKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQ 1848
            LL  ++  L    H +++ K CP+CG ++VPYPLST+P+CG+  Y +RC+     L+ D LN SSYL+  I   +QR++++P P L    TC+  D   S+G+ L+   PF I+S NT+   NCS  +L    NC+ +SLCH Y++ +       A         CC +  GG  +AYKIR+    C A+ S + LD      S W E G+EI W   PEP CK  +DC    +S C  A   G  RCLC  G+ WD     C     +S +  ++ + IG +   S+        V RS  FS    L K RE+ML ++   GKSA++F+ KE+ +ATN FSKD VLGSGGFGEV+K                                  VNH++LVKL+GCC+E EQPL+IY YI NGTL EHLH       +   L W  RL IA QTAE LAYLH +    IYH D+KS+NILLD+  NAKVADFGLSRLA    SH++TCAQGTLGYLDPEYY N+QLTDKSDVYS+G+V+LELLTS+K IDF+R+ +D+NL +YV     +  +M  +D R+      VE+ T ++    LA ACL E++  RPSMK V  E++ II  V  +
Sbjct:   11 LLCSSLLFLLFFCHHSSSQKDCPNCGSIQVPYPLSTNPNCGDPDYSLRCDGDSQKLYFDGLNGSSYLVLRIMASSQRMVVQPSPWLPG--TCVTQDMPVSEGLWLNQTRPFKITSSNTIFLFNCSPRLLVSPLNCTPSSLCHHYLESSGHVDRKRALQCASGLDPCCTFVAGGMPSAYKIRLHSSGCRAFRSILGLDPEKPP-SQWEE-GLEIQWAPAPEPVCKTQLDC--TRDSKCSPAGGKGLLRCLCNRGYYWDLARGTCLKKEKNSKLAISLKVSIGVVSFFSLAVAIAAVTVRRSGKFSNQEKLVKAREEMLKSS-MGGKSARMFSLKEVKKATNGFSKDRVLGSGGFGEVYK----------------------------------VNHKNLVKLLGCCVEAEQPLMIYNYIPNGTLHEHLHG-----KRSTFLKWDTRLRIALQTAEALAYLHSAAHTPIYHRDVKSTNILLDEDFNAKVADFGLSRLAEPGLSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSYGIVMLELLTSQKAIDFSREPDDINLAIYVSQRASDGAVMGVVDQRLLGHNPSVEVITSIRLFSELALACLREKKGERPSMKAVVQELQRIIKFVDKE 594          

Query:    4 ENRVASLLILTMAILCCTGHTAA---TVKHCPD-CGHMRVPYPLSTSPDCG-NQQYKVRCNAGV-------------LWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKS---QGILLDNNLPFNISSGNTVIGMNCSNEML-----TLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSF----VNLDTSSGALSSWPEPGV-EIMWELPPEPE---C-KLPIDCGDLMNSV-----CLADRFG-----------------QRRCLCKAGFQWDAINAICHSLVFAAVAMLIGAIIGSVV----------YK--RRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            E  V S+L+L   +   T  TA      ++C + CG + +PYP     DC  N+ + V CN                L L  ++ +  L+T I+P+              V C   D      +GI L    PF  S GN +  + C+N +L     T+   CSS       V  N      C K  +         N  +   +  E    Y +F    +    SSG+   +      E++W +    E   C K  +  G L N       C A + G                 + RCL +   ++      C     A+   ++G  +G  +          YK  RR + +     F   +  +  +++N  + ++ KIFT  E+ +A++NF+++ +LG GG G V+KG+L DG I A+K++K  +    +Q  NE+ IL Q+NHR++VKL+GCCLE+E PLL+YE+I +GTLF+ +H  N      +  +W  RL IA + A  LAYLH +    I+H DIKS NILLD+K  AKVADFG SR    + +H+TT  +GT GYLDPEY+   Q T+KSDVYSFG+VL+ELLT +K I   R EE+ +L  Y    + E  L D +D ++    G    E + A+ ++A+ CL+   + RP+MKEVA E+E + S
Sbjct:  182 EMNVKSVLLLISLLWLTTASTATPSMAKQNCQERCGDVTIPYPFGIGKDCYLNEWFAVNCNDSFNPPTPYLSHPELNLKLTFVSLAYQLVTVISPMA-------------VYCQDHDRNRSTWKGIDLSKT-PFFYSEGNALRVVGCANSVLITRQGTILAGCSSICDNSSSVLSNGCYGINCCKTTVPSNLDFYILNTTWSTNMGTELNCTYAAFGRNFILRGKSSGSGMEYEASSEGEMIWMIKESVEGSDCHKNTVPDGALGNHSYYSCSCPAYQEGNPYLPNGCQVVEVCANCKGRCLTRIDGRF-----FCDERSLASKFWILGISLGGGLLFLLLGGFWLYKVLRRRRKIKLREQFFQQQLLQHQMSSNEISIENTKIFTFNELKKASDNFNENRILGRGGQGTVYKGMLTDGRIVAIKKSKIVDESQYEQFINEIVILSQLNHRNIVKLLGCCLEIEVPLLVYEFISHGTLFQLIHDEN----NELPFSWERRLEIATEVAGALAYLHSASSTPIFHRDIKSKNILLDEKYRAKVADFGTSRSVSIDQTHLTTLVRGTFGYLDPEYFRTGQFTEKSDVYSFGIVLVELLTGQKPISSTRTEEERSLASYFILSIEETNLFDILDAQVVKEGG---EEEIMAVVNVATQCLNLNGKKRPTMKEVALELERVKS 834          

Query:  901 EDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPR-IKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            +  ++++  A +  KIFT  E+ +AT+NF+K+ +LG GG G V+KG+L+DG I AVK++K  +   ++   NE+ IL Q+NHR++V ++GCCLE E PLL+YE+I NGTLF+ +H  N        L+W MRL IA + +  L+YLH +    IYH DIKS+NILLDDK  AKV+DFG SR    + +H+TT  QGT GYLDPEY+ + Q T+KSDVYSFGVVL+ELLT +K I   R  E+ +L  +    L+E RL D +D R +K+G      E +     LA  CL+   + RP+MKEV  EI+ I
Sbjct:  239 QQQISSDKIAFEKTKIFTSDELEKATDNFNKNRILGQGGQGTVYKGMLNDGRIVAVKKSKIVDENQLEHFINEIVILSQINHRNVVGILGCCLETEVPLLVYEFISNGTLFQLIHDQN----SEFPLSWEMRLRIALEVSGALSYLHSACSIPIYHRDIKSTNILLDDKYKAKVSDFGTSRSISIDQTHLTTIVQGTFGYLDPEYFQSSQFTEKSDVYSFGVVLVELLTGQKPISSTRSPEEKSLATHFILSLQESRLFDILDARVVKEG----RKEDIMTFAKLAGRCLNLNGRKRPTMKEVTTEIDNI 540          

Query:  538 VRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDA-------------------INAICHS-----LVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGK-SAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            V K  C   +S +++D  + +        V++ W L  E +C     C ++   V     F   RC C+ GF  D                    I+  C       ++   +A++I         +R   + AR++    T+ R      + + GK S  I+  + I +AT++FS+   LG+G +G V+ G L +  + A+KR K  +T  ++++ NE++++  V+H +LV+L+GC +E  + +L+YE++ NGTL +HL     N      L W +RL+IA QTA+ +A+LH ++ P IYH DIKSSNILLD     K+ADFGLSRL M ESSHI+T  QGT GYLDP+Y+ NF L+DKSDVYSFGVVL+E++T+ KV+DF+R + +VNL     + + + RL + IDP ++       L ++  +  LA  CL   R  RPSM EVA E+E I
Sbjct:  162 VSKSHCQYLLSSISVDAFNTSSVVLDVGIVQLGWWLLGECKCHQEATCTEIQTPVAGQQGF---RCKCRDGFDGDGYQAGVGCRKASSGCNPSRYISGQCGGPSRFFVLAGGIALMISISAICCFMRRCLTSKARNS----TRRR-----LSEATGKCSIPIYPYRAIEKATSSFSEKQRLGTGAYGTVYSGKLHNQWV-AIKRIKHRDTDSIEEVLNEIKLISSVSHPNLVRLLGCSIEKGEQILVYEFMANGTLSQHLQRERGN-----GLVWAVRLSIATQTAQAIAHLHSALNPPIYHRDIKSSNILLDHNFIPKLADFGLSRLGMAESSHISTAPQGTPGYLDPQYHQNFHLSDKSDVYSFGVVLVEIITALKVVDFSRPQNEVNLAALAIDRIGKGRLDEIIDPFLEPHRDAWSLSSLHKVAELAFRCLAFHRDMRPSMMEVAAELEQI 598          

Query:  676 DCGDLMNSVC-----LADRFGQRRCLCKAGFQW-----------DAINAICHSLVFA----AVAMLIGAIIGSVVYKRRDQNVARSAHFSLTK------FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            +C D  N++C       + +G   C C  G+             D +      LV +    AV +LI   +G  ++++ ++         L K       ++ + ++   + +  K++T +E+ +AT+NF+   VLG GG G V+KG+L DG+I A+K++   + + +    NEV IL Q+NHR +VKL+GCCLE E PLL+YEY+ N TL  HLH  N  +     L+W  RL IA + A  LAYLH    P I H DIKSSNILLD+   A V+DFGLSR    E +H+TT  QGT GYLDP Y+ + Q TDKSDVY+FGVVL ELLT +KVI  +R E   +L  + +  +++  L + +D  I D     + E + A+  LA  CL    + RP+MKE+A +++ +
Sbjct: 1068 ECMDPNNTLCKKGAVCINTYGGYYCACPPGYHSHDSQPEHGCVRDKVKLKAAILVTSGIGIAVVLLILLAVGFWLHRQLEERKKNKLKQKLFKRNGGLLLQQQITSSGKGSVEKTKLYTIEELEKATDNFNASRVLGRGGHGTVYKGMLLDGSIVAIKKSIIVDERQVVTFVNEVFILSQINHRHIVKLLGCCLESEVPLLVYEYVSNSTLSHHLHDRNCESK----LSWEKRLRIADEIAGALAYLHTYASPAILHRDIKSSNILLDEHFRAVVSDFGLSRSITHEKTHLTTLVQGTFGYLDPGYFRSGQFTDKSDVYAFGVVLAELLTGEKVICSSRSE--ASLATHFRLAMKQNYLFEILDKVILDDG---QKEEILAVARLAKICLKLGGKKRPTMKEIAADLDQL 1468          

Query:  925 SAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            S+ +  K++T  E+ +AT+NF+   VLG GG G+V+KG+L DG+I A+K++   + + + +  NEV IL Q+NHR +VKL+GCCLE E PLL+YEYI N TL  HLH    N     +L+W  RL IA + A  LAYLH      I H DIKS NILLD+   A V+DFGLSRL   E +H++T  QGT GYLDPEY+ + Q TDKSDVY FG++L ELLT +KVI  +R EE  +L ++ +  +++  L + +D  I +     + + + A+  +A  CL    + RP+MKE+A ++  +
Sbjct:  451 SSVEKTKLYTIGELEKATDNFNAGRVLGKGGRGKVYKGMLLDGSIVAIKKSIVVDERQVVEFINEVFILSQINHRHIVKLLGCCLESEVPLLVYEYISNNTLSHHLH----NEDHASTLSWEKRLRIADEIAGALAYLHSYASTAILHRDIKSRNILLDENFRAVVSDFGLSRLIAHEKTHLSTLVQGTFGYLDPEYFRSGQFTDKSDVYGFGMILAELLTGEKVICSSRSEE--SLAIHFRLAMKQNCLFEILDKVIVNEG---QKKEILAVAKIAKRCLKLSGKKRPAMKEIAADLHQL 742          

Query:  901 EDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            +  ++++  + +  K+++ +E+ RAT+ F+   V+G GG G V+KG+L +G+I A+K++   + K +DQ  NEV IL Q+NHR +V+L+GCCLE E PLLIYEY+ NGTLF HLH    +     +L+W  RL I  + A  LAYLH      I H DIKSSNILLD+ L A V+DFGLSR    + +H+T   QGT GYLDP+Y+ + Q TDKSDVY+FGVVL ELLT ++ I  +R E+   L  + ++ +++ RL + +D ++ +     + E + A+  LA  CL    + RP+MK+V  +++ +
Sbjct:  431 QQQISSSKESVEKTKLYSVEELERATDGFNSGRVIGKGGLGTVYKGMLSNGSIVAIKKSNTVDEKELDQFVNEVFILSQINHRHIVRLLGCCLETEVPLLIYEYVSNGTLFHHLH----DEGHASTLSWKNRLRIGSEIAGALAYLHSYASIAICHRDIKSSNILLDENLRAVVSDFGLSRSIPLDKTHLTALVQGTFGYLDPDYFHSGQFTDKSDVYAFGVVLAELLTGEQAISSDRSEQ--GLANHFRSAMKQNRLFEILDNQVVNEG---QKEEIFAIAKLAKRCLKLNGKKRPTMKQVDIDLQQL 730          

Query:   13 VASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAIC 780
            +A LL+ T A+L C    A +   CPDCG   VPYPLST  DCG+Q+YK+R + G L  D++NSS Y I  I+P TQRL+IRP   A + TC+  DF  QGI L+N+LPFN++S NT++ +NC+  +     NCSS SLCH Y+ +    A+AC   P+CC +K GGS  AY IRVR+  CSAY SFVNLD ++  L  WPEPGVE+ W  P EP C+   DC + MNS C  D    G  RC CK+G  WD+I  +C
Sbjct:    1 MAKLLLFTAALLLCAV-CAMSANRCPDCGTTPVPYPLSTGADCGDQEYKIRFDEGKLIFDSVNSS-YSIAFISPETQRLVIRPASFAGD-TCITTDFPKQGIQLNNSLPFNVTSSNTIMFLNCTESLFRSPLNCSSISLCHTYI-NGTQDAAACVDAPICCTFKAGGSTTAYSIRVRESGCSAYQSFVNLDPNA-PLDRWPEPGVELQWVSPREPVCRSQADCTEGMNSTCGPDPATTGVSRCFCKSGLSWDSIAGLC 253          

Query:  901 EDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACL 1767
            +  ++++  + +  K+++ +E+ RAT+ F+   V+G GG G V+KG+L DG+I A+K++   + K +DQ  NEV IL Q+NHR +V+L+GCCLE E PLL+YEY+ NGTLF HLH    +     +L+W  RL I  + A  LAYLH      I H DIKS NILLD+ L A V+DFGLSR    + +H+T   QGT GYLDP+Y+ + Q TDKSDVY+FGVVL ELLT ++ I  +R E+   L  + ++ +++ RL D +D ++ +     + E + A+  L   CL
Sbjct:   94 QQQISSSKESVEKTKLYSVEELERATDGFNSSRVIGKGGLGTVYKGMLSDGSIVAIKKSNTVDEKQLDQFVNEVFILSQINHRHIVRLLGCCLETEVPLLVYEYVSNGTLFHHLH----DEGHASTLSWKDRLRIGSEIAGALAYLHSYASIAICHRDIKSRNILLDENLRAVVSDFGLSRSIPLDKTHLTALVQGTFGYLDPDYFHSGQFTDKSDVYAFGVVLAELLTGEQAISSDRSEQ--GLANHFRSAMKQNRLFDILDNQVVNEG---QKEEIFAVAKLTKRCL 373          

Query:  901 EDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGL-----SRLAMTESSHIT 1473
            +  ++++  + +  K+++ +E+ RAT+ F+   V+G GG G V+KG+L DG+I A+K++   + K +DQ  NEV IL Q+NHR +V+L+GCCLE E                    G+ +T     L+W  RL I  + A  LAYLH      I H DIKS NILL      ++ D        ++   T+SS+++
Sbjct:  607 QQQISSSKESVEKTKLYSVEELERATDGFNSSRVIGKGGLGTVYKGMLSDGSIVAIKKSNTVDEKQLDQFVNEVFILSQINHRHIVRLLGCCLETE--------------------GHAST-----LSWKDRLRIGSEIAGALAYLHSYASIAICHRDIKSRNILLHATYKLRINDIAYRSCFNNQSGKTDSSYVS 777          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR--FGQRRCLCKAGFQWDAINAICHSL---------------------VFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTE---SSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIV 1839
            ME  V  LL+  +A+L CT   A     C DCG   VPYPLST P CG+Q YKVRCNAG LW D L+ SSY+ITSINP T+R+I++P  L  N TC+  D +  G+ LD   P+NI S NT++ MNCSN +L  S NCS NS+CH Y++ N +AA+ACR    CC +KTGG  NAYKI VR E C AY SFVNL TS   +  WPEPG+EI W LP EP CK+P DC  L+NS+CL D    GQRRC CKAGF W  IN +C +L                     V    A+LI   +G +V + R QN+ R A  SL K REDMLNANNS GK AKIF+GKEI RATNNFSKDN +GSGGF EVFKG+LDDGT+TAVKRAK GNTKG DQ+ NEVRILCQVNHR LV+L+GCC+ELEQP++IYEYI NGTLF+HLH    ++ K  +LTW  RL+IA QTAEGLAYLH S VP IYH D+KSSNILLD+KL+AKV+DFGLSRLA+     +SHITTCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLELLTSKK IDFNR+EEDVNLV+Y+K I++EE+LMD IDP +KDGA  V++E++KALG LA+ACLDERRQ+RPSMKE A+EIEYIISI+
Sbjct:    1 MEKNVLPLLLHALALLLCT-RAAMCAPRCGDCGRXPVPYPLSTGPGCGDQSYKVRCNAGTLWFDALSQSSYVITSINPGTRRMIVKPASLLAN-TCITTDIQVGGLQLDRISPYNIPSSNTIMLMNCSNAVLNSSVNCSPNSICHAYIREN-VAAAACRSTXKCCWFKTGGPVNAYKIGVRDEGCMAYQSFVNLATSL-PVKRWPEPGLEIEWALPQEPICKIPKDCSTLLNSMCLPDGAILGQRRCFCKAGFHWGPINGLCQNLKCEKAKSCKHKKKSRTPLLGGVAVVAAILILVPVGILVCRHR-QNLKREAQGSLIKKREDMLNANNS-GKMAKIFSGKEIKRATNNFSKDNFIGSGGFSEVFKGILDDGTVTAVKRAKLGNTKGTDQVLNEVRILCQVNHRCLVRLLGCCVELEQPIMIYEYIPNGTLFDHLH--GHHSRKWPALTWRRRLSIALQTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKLDAKVSDFGLSRLAVVSEANASHITTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVLYIKKIMKEEKLMDVIDPVLKDGASKVDMESVKALGLLAAACLDERRQSRPSMKEAAEEIEYIISII 631          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR--FGQRRCLCKAGFQWDAINAICHSL---------------------VFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTE---SSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIV 1839
            ME  V  LL+  +A+L CT   A     C DCG + VPYPLST P CG+Q YKVRCNAG LW D L+ SSY+ITSINP T+R+I++P  L  N TC+  D +  G+ LD   P+NI S NT++ MNCSN +L  S NCS NS+CH Y++ N +AA ACR    CC +K GG  NAYKI VR E C AY SFVNL TS   +  WPEPG+EI W LP EP CK+P DC  L+NS+CL D    GQRRC CKAGF W  IN +C +L                     V    A+LI   +G +V + R QN+ R A  SL K REDMLNANNS GK AKIF+GKEI RATNNFSKDN +GSGGF EVFKG+LDDGT+TAVKRAK GNTKG DQ+ NEVRILCQVNHR LV+L+GCC+ELEQP++IYEYI NGTLF+HLH    ++ K  +LTW  RL+IA QTAEGLAYLH S VP IYH D+KSSNILLD+KL+AKV+DFGLSRLA+     +SHITTCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLELLTSKK IDFNR+EEDVNLV+Y+K I++EE+LMD IDP +KDGA  V++E++KALG LA+ACLDERRQ+RPSMKE A+EIEYIISI+
Sbjct:    1 MEKNVLPLLLHALALLLCT-RAAMCAPRCGDCGRIPVPYPLSTGPGCGDQSYKVRCNAGTLWFDALSQSSYVITSINPGTRRMIVKPASLLAN-TCITTDIQVGGLQLDRISPYNIPSSNTIMLMNCSNAVLNSSVNCSPNSICHAYIRENVVAA-ACRSTAKCCWFKAGGPVNAYKIGVRDEGCMAYQSFVNLATSL-PVKRWPEPGLEIEWALPQEPICKIPKDCSTLLNSMCLPDGAILGQRRCFCKAGFHWGPINGLCQNLKCEKAKSCKHKKKSRTPLLGGVAVVAAILILVPVGILVCRHR-QNLKREAQGSLIKKREDMLNANNS-GKMAKIFSGKEIKRATNNFSKDNFIGSGGFSEVFKGILDDGTVTAVKRAKLGNTKGTDQVLNEVRILCQVNHRCLVRLLGCCVELEQPIMIYEYIPNGTLFDHLH--GHHSRKWPALTWRRRLSIALQTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKLDAKVSDFGLSRLAVVSEANASHITTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVLYIKKIMKEEKLMDVIDPVLKDGASKVDMESVKALGLLAAACLDERRQSRPSMKEAAEEIEYIISII 631          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQN----CSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSG-ALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR--FGQRRCLCKAGFQWDAINAICHSL----------------VFAAVAMLIGAII-----GSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTES---SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVS 1854
            MEN V  + IL +A++  +   A  V+ C +CG + VPYPLST PDCG+Q YK+RC AG LW D +N SSY I +INPL +RLII+PP LANN +C+++DF SQGI LD+NLPFNISS NT++ +NC++ +  L  N    CS  S+CH+Y+K +   A+AC   PLCC ++TGG  N   ++V    CSAY SFVNLD  +  AL+ WPEP VEI W LP EP C+ P+DC +L+ S CLAD   FGQ+RC C AGF+WD IN +C ++                +FA VA+  GAI+     G + Y +  ++  R A  +L K R++MLNA +S GKSA+IFTGKEI +ATNNFSKDN++GSGGFGEVFKG+LDDGTITA+KRAK GNTKG DQ+ NEVRILCQVNHRSLV+L+GCC+ELE P++IYEYI NGTLFEHLH     +SK   L W  RL IA QTAEGLAYLH + +P IYH D+KSSNILLD++LNAKV+DFGLSRL  T     SHI TCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVL+E+LTSKK IDFNR+EEDVNLVVY+K ++ E+R++DAIDP +K+ A  +ELETMKALGSLA+ CLDE+RQNRPSMKEVADEI+YII I + +VS
Sbjct:    1 MENNVLMMSILMVALMSYSP-CAIAVRPCGNCGRLLVPYPLSTRPDCGDQHYKLRCTAGTLWFDGVNGSSYTIKTINPLIRRLIIQPPNLANN-SCISSDFHSQGIQLDHNLPFNISSSNTILLLNCTDSVSHLKLNPPMDCSPASICHNYIKEH---AAACIIAPLCCTFRTGGLQNVDALKVYVGECSAYQSFVNLDLKTVLALNKWPEPEVEIEWMLPQEPVCRTPVDCRELLYSKCLADPIIFGQKRCFCNAGFKWDPINGLCQNVKCRTGKACRKRKKKTALFAGVALAGGAILLVAVTGILFYNQHHRS--RQAQKNLIKERKEMLNAKHS-GKSARIFTGKEIIKATNNFSKDNLIGSGGFGEVFKGILDDGTITAIKRAKLGNTKGTDQVLNEVRILCQVNHRSLVRLLGCCVELELPIMIYEYIPNGTLFEHLHCNQ--SSKWTPLPWQRRLRIAHQTAEGLAYLHSAALPPIYHRDVKSSNILLDERLNAKVSDFGLSRLVETSENNDSHIFTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLMEILTSKKAIDFNREEEDVNLVVYMKKMIEEDRILDAIDPVLKESASKLELETMKALGSLAATCLDEKRQNRPSMKEVADEIQYIIGITSERVS 639          

Query:   85 CPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASAC----RKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRF--GQRRCLCKAGFQWDAINAICHSLVFA---------AVAMLIG--------------AIIGSVVYKRRD--------QNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTG--NFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEI 1818
            CP CG  RVPYPLST+P+CG+  YK+RC  G L+ D++N  SY IT+INP TQR I+ P G  NN TCM+ DF ++GI LD N PFNI+S NTV+ +NCSN + T  +NCS +S+CH YVK N +AA  C         CC  KTGGS  AY+IRVRKERCSAY SF NLD S   +S W  PGVE+ WELP EP C++  DC DL NSVC  +    G R+C+CK G++W ++N IC ++                LIG              +I   ++             Q +      SL++ R D+LNANNS G+SAKIFT KE+T+AT+NFSK N+LG GGFGEVFKG LDDGTITA+KRAKPGN +G+DQI NEV+ILCQVNHRSLV+L+GCC+EL +PLL+YEY+ NGTLFEHLH    N N+SK + L W  RL IA QTAEG+AYLH++ VPRIYH DIKSSNILLDD L+AKV+DFGLSRL +++++HITTCA+GTLGYLDPEYY+NFQLTDKSDVYSFGVVLLELLTSKK IDFNR+EEDVNLVV +K  LRE RLMD +DP +K G   +ELETMKA G+LA ACLD+RR+NRP+MK++ADEI
Sbjct:    2 CPTCGQTRVPYPLSTAPNCGDPSYKIRCTGGTLFFDSINGFSYAITAINPTTQRFILHPSGFLNN-TCMSTDFPNKGIWLDTNSPFNITSSNTVVLLNCSNNVFTTPRNCSLSSICHKYVKENDVAAKICGPRSHAPQTCCHIKTGGSVTAYRIRVRKERCSAYFSFPNLDPSL-PVSMW-RPGVELEWELPEEPSCRVNEDCLDLENSVCSPNPMIGGSRKCMCKRGYEWYSVNGICQNIKCEHGRGCKRRNKKTSLIGVHKNCLKNRFHSDTSIYQDIISNTNSIDTILNVRQRIKGETEQSLSRAR-DILNANNSGGRSAKIFTMKELTKATSNFSKANLLGFGGFGEVFKGTLDDGTITAIKRAKPGNIRGIDQILNEVKILCQVNHRSLVRLLGCCVELPEPLLVYEYVPNGTLFEHLHHHHHNNNSSKGIRLGWHSRLRIAHQTAEGIAYLHNAAVPRIYHRDIKSSNILLDDNLDAKVSDFGLSRLVVSDATHITTCAKGTLGYLDPEYYVNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVVLIKRALREGRLMDNVDPMLKSGDSRLELETMKAFGALAIACLDDRRKNRPTMKDIADEI 614          

Query:   46 LCCTGHTAAT----------VKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALS---SWPEPGVEIMWELPPEPECKLPIDCGDLMN-SVCLAD--RFGQRRCLCKAGFQWDAINAIC-------------HSLVFAAVAM-LIGAIIGSVVY----KRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLA-MTES----SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVSAT 1860
            L C GH+ A              CP+CG M VPYPLST P+CG+Q Y++ C  G L+   L+ SSY+ITSIN +TQR+++ PPGLA++V+C++AD   QG+ LD +LPF+I+S NT++ +NCS  ML    +CS  SLC+ Y+K+N   AS C K PLCC ++T GS  AY IR+    C AY SFV L+ +         WP+ G+E+ W LP EP CK  +DC  L+  S CL D    G +RC CK G +WD +NAIC              ++VFA VA+ ++GA +   V     K   Q V +  H ++ K RE+ML+AN S GKS++IFTG+EIT+ATNNFSKDN++G+GGFGEVFK VL+DGTITA+KRAK  NTKG DQI NEVRILCQVNHRSLV+L+GCC++LE PLLIYE+I NGTLFEHLH    +T K   LTW  RL IA QTAEGLAYLH +  P IYH D+KSSNILLDDKLNAKV+DFGLSRL  +TE+    SHI T AQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLE++TSKK IDF+R+EEDVNLV+Y+  ++ +ERL++ IDP +K  A  ++++TM+ LG+LASACL+ERRQNRPSMKEVADEIEYII+I++ +V+ T
Sbjct:   20 LACAGHSCARHAKAKPPMAGPPRCPNCGPMVVPYPLSTGPNCGDQAYRINCVGGKLYFGALHGSSYVITSINSVTQRIVLSPPGLASSVSCISADVSKQGLELDPHLPFSITSSNTILLLNCSQAMLQAPIDCSPTSLCYSYIKNN---ASPCSKAPLCCTFRTDGSQTAYTIRINSGGCLAYQSFVGLNPNKEVPPPGIKWPDTGLELQWALPKEPVCKTDVDCNLLLGKSKCLPDPTSLGLKRCSCKRGLEWDPVNAICGKCRHGKHCKKKKKTVVFAGVAVAVVGATLAIAVAVIATKHSHQKVKKDLHKNIVKEREEMLSAN-STGKSSRIFTGREITKATNNFSKDNLIGTGGFGEVFKAVLEDGTITAIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLGCCVDLELPLLIYEFIPNGTLFEHLHGNPDHTWK--PLTWRRRLQIAYQTAEGLAYLHSAAQPPIYHRDVKSSNILLDDKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFSREEEDVNLVMYINKMMDQERLIECIDPLLKKTASKLDMQTMQQLGNLASACLNERRQNRPSMKEVADEIEYIINILSQEVTET 657          

Query:   19 SLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAICHS---------------------LVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQV 1851
            +LL+ T A+L C    A     CPDCG+  VPYPLST  DCG+Q+YK+RC+AG L  DTLNSS Y I+SI P  QR +IRP   A N TC+  D  +QGI L+ +LPFN++S NT++ +NC++ +L    NCSS SLCH Y+ +    A+AC   P+CC +K GGS  ++ IRVR   C AY SFVNLD S+  ++ WPEPGVEI W  P EP C    DC D MNS C  D    G  RC CK+G  WD +  +C                       L     A LI A+I  +VY+R  +   + A   L + RE++LNAN   GK AK FTGKEI RATN+FS D +LG+GG+GEV+KG+LDDGTI A+K AK GN KG DQ+ NEV ILCQVNHRSLV+L+GCC+ELEQP+++YE+I NGTL EHL         R SLTW  RL IA  TAEGLAYLH S VP IYH D+KSSNILLD+K+NAKVADFGLSRLA T+ SH++TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDFNR  +DVNL VYV+  + EERLMDAIDP +K+ A  +ELETMKA+G LA  CL+ERRQNRPSMKEV +EI YIISI T +V
Sbjct:    3 NLLLFTAALLLCAV-CAMAANRCPDCGNTSVPYPLSTGADCGDQEYKIRCDAGTLRFDTLNSS-YSISSITPQIQRFVIRPASFAGN-TCVTTDLPNQGIQLNESLPFNVTSSNTILYLNCTDTLLRSPLNCSSISLCHTYI-NGTRDAAACEDAPICCTFKAGGSTTSHSIRVRDAGCRAYRSFVNLDAST-PVNRWPEPGVEIQWVSPREPVCTSQSDCTDGMNSTCGPDPATAGVSRCFCKSGLWWDPVGGLCAQNVTCQDPDGCGSTNKTPLIAGLTVGIGAALIAAVIAILVYRRHRR--IKEAQDRLAREREEILNANGG-GKFAKNFTGKEIKRATNSFSHDRLLGAGGYGEVYKGILDDGTIVAIKCAKLGNAKGTDQVLNEVGILCQVNHRSLVRLLGCCVELEQPIMVYEFIPNGTLLEHLQ--GQRPGGRGSLTWSHRLRIAHDTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKMNAKVADFGLSRLAHTDMSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNRPADDVNLAVYVQRTVEEERLMDAIDPLLKEQASSLELETMKAMGFLAVGCLEERRQNRPSMKEVTEEIGYIISIATAKV 626          

Query:   37 MAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKH----NPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD---RFGQRRCLCKAGFQWDAINAIC---------------HSLVFAAVAMLIGAIIGSV-----VYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVT 1842
            + +L C    A + + C DCG   VPYPLST PDCG+Q YK+RC +  L  DTLN+S Y ITSI+P TQRL I+P     N TC+  D  + G+ L+++LPFNI+S NT++ +NCS  +LT   NCSS SLCH YV      N  A  ACR  P+CC ++ GGS+ +Y IRVR+  C AY SFVNLD SS  +S WP+PG+E+ W  PPEP C    DC    +S C  D     G  RC C +GF WD I A+C               H+ + A +   +G  + +V     VY+R  +   + A   L + RED+L++     K+AK+FTGKEI +ATNNFS+D +LG+GG+GEV+KGVLDDGT  AVK AK GNTKG DQ+ NEVRILCQVNH+ L++++GCC+ELEQPLL+YEY+ NGTL +HL   N     R  LTW  RL++A  TAEGLAYLH S VP IYH D+KSSNILLD++LNAKV+DFGLSRLA  + SH++TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDF+R ++DVNL VYV+ ++ EER+MDA+DP +K+GA  ++LETMKALG LA +CL+ERRQNRPSMKEVA+EIEYIISI T
Sbjct:   13 LLLLMCAAAPALSARRCADCGSSPVPYPLSTGPDCGDQSYKIRCTSTQLLFDTLNNS-YPITSISPETQRLTIQPSPFLPN-TCITQDISTIGVQLNSSLPFNITSSNTIVYLNCSETLLTSPLNCSSASLCHAYVNGSSSGNGGAVGACRSAPICCTFRAGGSSTSYMIRVRESGCRAYRSFVNLD-SSLPVSRWPQPGLELQWVSPPEPVCTAQSDCDS--DSTCTPDPNSNGGISRCFCHSGFHWDPIAALCAQDVTCEDSDGCGSDHTALIAGLTSGLGVAVIAVAIAVFVYRRHKR--IKDAQDRLAREREDILSSGGV--KNAKLFTGKEIRKATNNFSRDRLLGAGGYGEVYKGVLDDGTDVAVKCAKLGNTKGTDQVLNEVRILCQVNHKCLLRILGCCVELEQPLLVYEYVPNGTLSDHLQGPN-----RKLLTWDCRLSVAHATAEGLAYLHFSAVPPIYHRDVKSSNILLDERLNAKVSDFGLSRLAHADLSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFDRAQDDVNLAVYVQRLVEEERIMDAVDPALKEGASSLQLETMKALGFLAVSCLEERRQNRPSMKEVAEEIEYIISIAT 627          

Query:   22 LLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGV--LWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRF--GQRRCLCKAGFQWDAINAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQ 1848
            LL   + +L  T  T  + K CP+CG   VPYP STSP CG+Q YK+ CNA    L  DTLN+S Y I SIN   QRL I+P  L  N TC+ +DF  QGI ++++LPFNI+  NTV+ +NCS  +L    NCS  SLCH YV +N  + ++C+   +CC +K GG   AY IRVR   C AY SFVNLD     +  WP PGV I W LP EP C    DC D  NS C  D    G RRC C +GF WD +  IC+  + + +     AI  +++  +R + + + A   L + RE++LNA  S  ++AK+FTG+EI +ATN+FSKD +LG+GG+GEV+KG+LDDGT+ A+K AK GNTKG DQ+ NEVRILCQVNHRSLV L+GCC+ELEQP+L+YEYI+NG L +HL         ++S  W  RL +A  TA+GLAYLH S VP IYH D+KSSNILLDDKLNAKV+DFGLSRLA +E SHI+TCAQGTLGYLDPEYY  +QLTDKSDVYSFGVVLLELLTS K IDF R E+DVNL VYV+ +  EE+LMD +DP +K+   I+ELETMKALG LA  CL+E+RQNRPSMKEVA+EIEYI+SI T +
Sbjct:   10 LLFTALLLLTFTTITTFSAKPCPNCGTTPVPYPFSTSPTCGDQSYKITCNASTNELMFDTLNNS-YPIISINTTIQRLTIQPATLLQN-TCVTSDFLHQGIQMNSSLPFNITGDNTVMFLNCSESLLRSPLNCSFTSLCHSYV-NNTKSDASCKGASICCTFKAGGGTTAYMIRVRDTGCKAYTSFVNLDPGL-PVDKWPNPGVSIQWRLPQEPVCGSKADCDD-GNSNCKPDPILSGTRRCFCNSGFVWDPVEGICNKRLTSGLGASFLAIATAILLYKRQKRI-KEAQERLAREREEILNAGGS--RAAKLFTGREIKKATNHFSKDRLLGAGGYGEVYKGILDDGTVVAIKCAKLGNTKGTDQVLNEVRILCQVNHRSLVCLLGCCIELEQPILVYEYIQNGALLDHLQGKGLGGQGQLS--WIQRLRVAHDTADGLAYLHFSAVPPIYHRDVKSSNILLDDKLNAKVSDFGLSRLAHSELSHISTCAQGTLGYLDPEYYRKYQLTDKSDVYSFGVVLLELLTSMKAIDFARAEDDVNLAVYVQRMAEEEKLMDVVDPMLKEKTSILELETMKALGFLALGCLEEKRQNRPSMKEVAEEIEYIMSIATTK 612          

Query:   37 MAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFP---LCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAICH------------------SLV--FAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVS 1854
            + IL C     AT + C +CG + VPYPLST+P CG+  YK+ C  G LWLD +NSSSY+ITSI P+           ANN                                         S NCSS S CH+Y++ N +A SAC        CC +KTGGS N ++IRVR ERCSAY SFVNLD     +S WPEPGVE+ W LP EP+   P+  G             Q+RC C+ GFQWD IN +C                   SL+   A  AM +G     VVY++  Q+    AH SL+K RE +L+ + S G   +IFT KEITRATNNFS +N+LGSGGFGEVFKG++DDGT  A+KRAK GNTKG+DQI NEVRILCQVNHR LVKL GCC+ELE PLL+YEYI NGTLF+HLH     +SKR  LTW  RL IA QTAEGLAYLH S  P IYH DIKSSNILLD++LNAKV+DFGLSRLA+T++SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKK IDFNR +E+VNLV+Y +  L+ E+L+DA+DP +K+GA  +ELETMKALGSLA+ACLDE+RQNRP+MKE ADEIEYIIS+VT+ VS
Sbjct:    2 LPILSCIRQVQAT-RQCRNCGRIPVPYPLSTAPGCGDPLYKLSCRGGTLWLDAVNSSSYIITSIYPVDPT--------ANNPAPXXP-----------------------------------SMNCSSASRCHEYLRENAIAKSACEATADKQRCCWFKTGGSLNEFRIRVRSERCSAYQSFVNLDMDL-PVSKWPEPGVELEWMLPFEPD---PVSVG-------------QKRCFCRDGFQWDPINGVCQMGRNCKHGGYCNKQTRKTSLIGALAVGAMFLGITTMVVVYRKYSQSRRELAHVSLSKVRERILSVSTS-GIVGRIFTSKEITRATNNFSSENLLGSGGFGEVFKGIIDDGTTIAIKRAKTGNTKGIDQILNEVRILCQVNHRCLVKLHGCCVELEHPLLVYEYIPNGTLFDHLH--KICSSKREPLTWLRRLVIAHQTAEGLAYLHSSATPPIYHRDIKSSNILLDNELNAKVSDFGLSRLAVTDTSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKAIDFNRVDEEVNLVIYGRKFLKGEKLLDAVDPFVKEGASKLELETMKALGSLAAACLDEKRQNRPTMKEAADEIEYIISLVTSGVS 566          

Query:   28 ILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAG-VLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR---FGQRRCLCKAGFQWDAINAICH------------------SLVFAAV----AMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQV 1851
            +L + +   T  ++AT+  CP CG+  VP+PLST+P CG+  YK+RC++   L  DTLN+S Y I SI+P +QR +IRP  L  N TC++ D   QGI L+  LPFNI+S NT++ +NC+  +L    NCS+ S CH Y+K    AA+     PLCC Y+TGGS+N+Y +RVR   CSAY SFVNL+ +   ++ WPEPG+EI W  P E  C    DC D   S C  D     G RRC C  G  WD I  +C                   +++  +V    A LI A+I  ++YKR  +   + A   L K RE +LNA+N  G++AK+F+GKE+ +ATN+FS D +LG GG+GEV+KG+L DGT+ AVK AK GN KG DQ+ NEVRILCQVNHR+LV L+GCC+ELEQP+++YE+I NGTL +HL  G    S+ + LTW  RL IAR TAEGLAYLH   VP IYH D+KSSNILLD K+NAKV+DFGLSRLA T+ SHI+TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLT++K IDFNR  +DVNL +YV  ++ EE+LMD IDP +K+GA  +ELETMKA+  LA  CL+E+RQNRPSMKEVA+EIEYIISI + +V
Sbjct:   24 LLLLLLSRATHVSSATL--CPPCGNTTVPFPLSTTPTCGDPSYKIRCSSSNTLVFDTLNNS-YPIESIDPNSQRFVIRPAPLLTN-TCVSTDKVHQGIQLNTTLPFNITSSNTIVYLNCTTTLLQSPLNCSAASACHSYIKATASAAACQGAGPLCCTYRTGGSSNSYMLRVRDSGCSAYSSFVNLNPAL-PVNRWPEPGLEIQWLSPKETVCGSQQDC-DSATSTCGPDASSALGIRRCFCNDGLVWDPIQGVCAKKITCQNPGGCDDSTSRTAIIAGSVCGVGAALILAVIAFLLYKRHRR--IKEAQARLAKEREGILNASNG-GRAAKLFSGKELKKATNDFSSDRLLGVGGYGEVYKGILQDGTVVAVKCAKLGNPKGTDQVLNEVRILCQVNHRNLVGLLGCCVELEQPIMVYEFIENGTLLDHLQ-GQMPKSRGL-LTWTHRLQIARHTAEGLAYLHFMAVPPIYHRDVKSSNILLDIKMNAKVSDFGLSRLAQTDMSHISTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTAQKAIDFNRAADDVNLAIYVHRMVAEEKLMDVIDPVLKNGATTIELETMKAVAFLALGCLEEKRQNRPSMKEVAEEIEYIISIASAKV 646          

Query:   19 SLLILTMAI--LCCTGHTAAT----------VKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGAL---SSWPEPGVEIMWELPPEPECKLPIDCGDLMN-SVCLAD--RFGQRRCLCKAGFQWDAINAIC-------------HSLVFAAVAMLIGAI-----IGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLA-MTES----SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVSAT 1860
            +LLI T+    L C GH+ A              CP+CG M VPYPLST P CG+Q Y++ C  G L+   L+ SSY+ITSIN +TQR+++RPPGLA++V+C++AD   QG+ LD +LPF+I+S NT++ +NCS  ML    +CS  SLC+ Y+K+N   AS C K PLCC ++T GS  AY IR+    C AY SFV L+ +         WP+ G+E+ W LP EP CK  +DC  L+  S CL D    G +RC CK G +WD +NAIC              ++VFA  A+ +  +     +  +  K   Q V +  H ++ K RE+ML+AN S GKS++IFTG+EIT+ATNNFSKDN++G+GGFGEVFK VL+DGTITA+KRAK  NTKG DQI NEVRILCQVNHRSLV+L+GCC++LE PLLIYE+I NGTLFEHLH  +  T K   LTW  RL IA QTAEGLAYLH +  P IYH D+KSSNILLD+KLNAKV+DFGLSRL  +TE+    SHI T AQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLE++TSKK IDF R+EEDVNLV+Y+  ++ +ERL + IDP +K  A  ++++T++ LG+LASACL+ERRQNRPSMKEVADEIEYII+I++ +V+ T
Sbjct:    9 ALLIPTLLTVWLACAGHSCARHAKAKPPMAGPPRCPNCGPMVVPYPLSTGPTCGDQAYRINCVGGKLYFGALHGSSYVITSINSVTQRIVLRPPGLASSVSCISADVSKQGLELDPHLPFSITSSNTILLLNCSQAMLQAPIDCSPTSLCYSYIKNN---ASPCSKAPLCCTFRTDGSQTAYTIRINGGGCLAYQSFVGLNPNKEVPPPGKKWPDTGLELQWALPKEPVCKTDVDCNLLLGKSKCLPDPTSLGLKRCSCKKGLEWDPVNAICGKCRHGKHCKKKKKTVVFAGAAVAVVGVTLAIAVAVIGTKHSHQKVKKDIHKNIVKEREEMLSAN-STGKSSRIFTGREITKATNNFSKDNLIGTGGFGEVFKAVLEDGTITAIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLGCCVDLELPLLIYEFIPNGTLFEHLHGSSDRTWK--PLTWRRRLQIAYQTAEGLAYLHSAAQPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERLTECIDPLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYIINILSQEVTET 657          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRC-NAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQ----NCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKI-RVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAICH--------------------SLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHF-SLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVS-LTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYII 1830
            ME    SL   T+++L     T    K CP+CG  RVPYPLST  DCG+  Y++RC N G LW DTLN S+  I +I+P  QR ++RPPG   N  C++ D K  GI LD NLPFN+S  NTVI MNC+ + L        NCS NSLCH ++  N  A   CR    CC YKTG S N YK+ R R + CSAY SF+NLD +   +S W EP VEI+WE P EP CK   DC DL+NSVC  D    GQ+RC CK GFQWD++NA+C                      L     A+LI   I   +  ++++ +A +  + S+ K   ++L+ N++     +IFTGKEI +AT+NF+K N+LG GGFGEVFKG LDDGT  AVKRAK GN K + QI NEV+ILCQV+H++LVKL+GCC+ELE P+L+YE++ NGTLFEH++ G          L    RL IA QTA+GL YLH S  P IYH D+KSSNILLD+ L+ KVADFGLSRL +++ SH+TTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVL ELLT KK IDFNR+EEDVNLVV+V+  L+E RLMD IDP I  GA   E+E+MKALG LA  C+ E RQ RP+M+  A EIE I+
Sbjct:    1 MELPWLSLTTFTLSLLIYFSSTTQAFKRCPNCGSTRVPYPLSTGLDCGDPGYRIRCDNYGSLWFDTLNGSTNPIKTIDPSGQRFVLRPPGFEQN-KCVSVDIKYHGIQLDLNLPFNVSCSNTVIIMNCTKDGLDAYSSQGFNCSDNSLCHKFLNANLEARGNCRGVTSCCWYKTGASVNTYKVYRARPDMCSAYQSFMNLDLTI-PVSKWGEPAVEILWEAPREPVCKSQGDCRDLLNSVCSNDSTNLGQKRCFCKKGFQWDSVNAVCEVNRCSKRKSCKRWSNLPLLGGLAGGVGAILIAGFITKTIVSKQNRRIAGNQSWASVRKLHRNLLSINSTG--LDRIFTGKEIVKATDNFAKSNLLGFGGFGEVFKGNLDDGTTVAVKRAKLGNEKSIYQIVNEVQILCQVSHKNLVKLLGCCIELEMPVLVYEFVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLFELLTCKKAIDFNREEEDVNLVVFVRKALKEGRLMDVIDPVIGIGATEKEIESMKALGVLAELCVKETRQCRPTMQVAAKEIENIL 636          

Query:  835 VVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            ++ KRR  N+ RS  F         +  L   +   + +KIF+ KE+ +AT+NFS D VLG GG G V+KG+L DG+I AVKR+K  +   M++  NE+ +L Q+NHR++VKL+GCCLE E P+L+YEYI NG LF+ LH    + S   ++TW +RL IA + A  L Y+H +    I+H DIK++NILLD+K  AKV+DFG SR    + +H+TT   GT GY+DPEY+L+ Q T KSDVYSFGVVL+EL+T +K +   R EE   L  +    ++E R++D ID RIKD +   +LE + A+  LA  CL+ + +NRP+MKEV++E+E I S
Sbjct:  378 LIKKRR--NINRSKKFFKRNGGLLLKQQLTTKDGNVEMSKIFSSKELRKATDNFSIDRVLGQGGQGTVYKGMLVDGSIVAVKRSKVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLH----DESDDYTMTWEVRLRIAIEIAGALTYMHSAASFPIFHRDIKTTNILLDEKYRAKVSDFGTSRSVTLDQTHLTTLVAGTFGYMDPEYFLSSQYTHKSDVYSFGVVLVELITGEKPLSRVRSEEGRGLATHFLEAMKENRVIDIIDIRIKDES---KLEQVMAVAKLARKCLNRKGKNRPNMKEVSNELERIRS 704          

Query:  811 LIGAIIGSVVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            L+  I G + + ++ + + R   F         +  L       +S+KIF+ KE+ +AT+NF+ + VLG GG G V+KG+L DG I AVKR+K  +   +++  NEV +L Q+NHR++VKLMGCCLE E P+L+YE+I NG LF+ LH    + S   ++TW +RL I+ + A  LAYLH +    +YH D+K++NILLD+K  AKV+DFG SR    + +H+TT   GT GYLDPEY+   Q TDKSDVYSFGVVL+EL+T +K     R EE+  LV +    +++ R++D +D RIK+G     LE + A+  LA  CL  + + RP+M+EV+ E+E I S
Sbjct:  360 LVLGIWGLIKFVKKRRKIIRKRMFFKRNGGLLLKQQLTTRGGNVQSSKIFSSKELEKATDNFNMNRVLGQGGQGTVYKGMLVDGRIVAVKRSKVLDEDKVEEFINEVGVLSQINHRNIVKLMGCCLETEVPILVYEHIPNGDLFKRLH----HDSDDYTMTWDVRLRISVEIAGALAYLHSAASTPVYHRDVKTTNILLDEKYRAKVSDFGTSRSINVDQTHLTTLVAGTFGYLDPEYFQTSQFTDKSDVYSFGVVLVELITGEKPFSVMRPEENRGLVSHFNEAMKQNRVLDIVDSRIKEGC---TLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIRS 696          

Query:  658 ECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            EC++P  CG+    V +A R+     + K       +  +   L+   +   +  I G   + R+ + + RS  F         +  L   + + + +KIF+ +E+ +AT+NFS D VLG GG G V+K +L DG+I AVKR+K  +   M++  NE+ +L Q+NHR++VKL+GCCLE E P+L+YEYI NG LF+ LH    +      +TW +RL IA + A  L+Y+H +    I+H DIK++NILLD+K  AK++DFG SR   T+ +H+TT   GT GY+DPEY+L+ Q T KSDVYSFGVVL+EL+T +K +   R EE + L  Y    ++E R +D ID RIKD     E + + A+  LA  CL+ +   RP+M+EV+ ++E I S
Sbjct:  319 ECEVPNKCGE-DTCVNMAGRYSCVPKITKPAKLAHVLRGVLIGLL--GLLFFVIGIFGLYKFIRKRRRIIRSMKFFKRNGGLLLKQQLTTKDGSVEMSKIFSSRELEKATDNFSIDRVLGQGGQGTVYKRMLVDGSIVAVKRSKVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLH----DEYDDYMMTWEVRLRIAVEIAGALSYMHSAASFPIFHRDIKTTNILLDEKYRAKISDFGTSRSVATDQTHLTTLVAGTFGYMDPEYFLSSQYTHKSDVYSFGVVLVELITGEKPMSRVRSEEGIGLATYFLEAMKENRAVDIIDIRIKD-----ESKQVMAVAKLARRCLNRKGNKRPNMREVSIKLERIRS 701          

Query:  406 QNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIR-----VRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELP---PEPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAI--CHSLVF-----------AAVAMLIGAIIGSVV---YKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMT---ESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            QN SSN L  +    N +  S C K P+ CL   G +     +      V    C  + S ++    S  L       +++ W L        C    DC      V L D     RC C+ GF   A      CH LV+               +L+G ++  V+   Y  R++  A S   S+     + L    +   S   +T KEI +AT++FS  N+LG+G +G V+ G   + +  A+KR K  +T  +DQ+ NE+++L  V+H +LV+L+GCC    +P L+YE++ NGTL++HL     +   +  L+W +RL IA QTA  +A+LH SV P IYH DIKSSNILLD + N+K++DFGLSRL M+   E+SHI+T  QGT GYLDP+Y+ +FQL+DKSDVYSFGVVL+E+++  KVIDF R   +VNL     + +   R++D IDP +          ++  L  LA  CL   R  RP+M E+ +++  I
Sbjct:  113 QNKSSNCLIRNKFVENRLNLSKC-KSPVSCL--DGATTTTADVMSLGDVVNGSGCKYWFSSISQSQVSVNLGR-----LKLDWWLKGSCSNTTCSENADCA----KVKLDDGGLGHRCTCREGFSGKAFTVPGGCHRLVYKRKGLHKLVVLGTAGILVGVLVIVVLIATYFFRNKQSASSERASIA----NRLLCELAGNSSVPFYTYKEIEKATDSFSDKNMLGTGAYGTVYAGEFPNSSCVAIKRLKHKDTTSIDQVVNEIKLLSSVSHPNLVRLLGCCFADGEPFLVYEFMPNGTLYQHLQ----HERGQPPLSWQLRLAIACQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFNSKISDFGLSRLGMSTDFEASHISTAPQGTPGYLDPQYHQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLASLAVDRIGRGRVVDIIDPCLNKEINPKMFASIHNLAELAFRCLSFHRNMRPTMVEITEDLHRI 593          

Query:   94 CGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNC--SNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKI----RVRKERCS---AYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPE---CKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAICH---------------------SLVFAAV--AMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            CG + +PYP   S  C     +  C+A                S+  +T+  I    GL++N T    D      L   N  F  +S N+ +  NC  + +  ++ Q    N L          +  A        L     S N+ K      +R   CS   + ++F ++  ++G    +    V + W L    E   C    DC D    V     +   RC C  GF  D     C                      ++V   V  A L+ A+      KRR     RS H S  +   +   A NS   S   F  KEI +AT+ FS+   LG G +G V++G L +    A+KR +  +++ +DQ+ NE+++L  V+H +LV+L+GCC+E   P+L+YEY+ NGTL EHL        +   L W +RLT+A QTA+ +AYLH S+ P IYH DIKS+NILLD   N+KVADFGLSRL MTESSHI+T  QGT GYLDP+Y+  F L+DKSDVYSFGVVL E++T  KV+DF R   ++NL     + +    + + IDP +        L ++  +  LA  CL      RP+M EVADE+E I
Sbjct:   52 CGGLTLPYPFGFSNGC---SIRFDCSAA-------EKPMIGDFSVQNVTENSIF--VGLSHNCTRKIEDMNP---LFGEN--FAPTSENSFLMENCNRTTDGCSIKQKFLENVL-------KLKSCDATGNISCFSLDSNSSSKNSAKFFSMKTLRNSSCSLLFSSIAFESVGVNAGIALEFER--VRLGWWLKGGCESGTCAANTDCTD----VETPHGYAGHRCSCLDGFHGDGYTNPCQRALPECRGSKLVWRHCRSNLITIVGGTVGGAFLLAALAFFFFCKRRRSTPLRS-HLSAKRLLSEA--AGNS---SVAFFPYKEIEKATDGFSEKQKLGIGAYGTVYRGKLQNDEWVAIKRLRHRDSESLDQVMNEIKLLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHL-----QRDRGSGLPWTLRLTVATQTAKAIAYLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQI 623          

Query:  808 MLIGAIIGSVVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            + IG I     + RR + + +   F         +  L        S ++F  +E+ +AT NFS   +LG GG G V+KG+L DG I AVK++K  +   +++  NEV IL Q+NHR++VKL+GCCLE + P+L+YE+I NG LFEHLH    ++      TW +RL IA   A  L+YLH +    IYH DIKS+NI+LD+K  AKV+DFG SR    + +H+TT   GT+GY+DPEY+ + Q TDKSDVYSFGVVL EL+T +K + F R +E   L  Y    ++E RL D ID RI+DG    +L  + A   +A  CL+ + + RPSM++V+ E+E I S
Sbjct:  371 VFIGGIYWLYKFIRRQRRLNQKKKFFKRNGGLLLQQQLTTTEGNVDSTRVFNSRELEKATENFSLTRILGEGGQGTVYKGMLVDGRIVAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETDVPILVYEFIPNGNLFEHLHD---DSDDYTMTTWEVRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNIMLDEKHRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQSSQFTDKSDVYSFGVVLAELITGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIRDGC---KLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRS 709          

Query:  946 IFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            +F+ +E+ +AT NFS + +LG GG G V+KG+L DG I AVK++K  +   +++  NEV IL Q+NHR++VKL+GCCLE + P+L+YE+I NG LFEHLH       + +  TW +RL IA   A  L+YLH S    IYH D+KS+NI+LD+K  AKV+DFG SR    + +H+TT   GT+GY+DPEY+ + Q TDKSDVYSFGVVL+EL+T +K I F R +E+  L  Y    ++E +L D ID RI+DG     L  + A   +A  CL+ + + RPSM+EV+ E++ I
Sbjct:  434 VFSSRELEKATENFSSNRILGQGGQGTVYKGMLVDGRIVAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETKVPVLVYEFIPNGNLFEHLHD---EFDENIMATWNIRLRIAIDIAGALSYLHSSASSPIYHRDVKSTNIMLDEKYRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQSSQFTDKSDVYSFGVVLVELITGEKSISFLRSQENRTLATYFILAMKENKLFDIIDARIRDGC---MLSQVTATAKVARKCLNLKGRKRPSMREVSMELDSI 721          

Query:   13 VASLLILTMAILCCTGHTAAT----VKHCPD-CGHMRVPYPLSTSPDC-GNQQYKVRCNAG-----VLWLDTLNSSSYLITSIN-------PLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEM---LTLSQNCSSNSLCHDYVKHNPMAASACRKFPLC------CLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPE-------PGVEIMWELP------PEPECK----------------------LPIDCGDLMNSVCL---ADRFGQRRCLCKAGFQ-----WDAINAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNS----AGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIE 1821
            V   L++ + +  C    A+T    +++C D CG++ VPYP      C  N+ +++ C +      +L L  +  +   +TS N        +  +  I+ P    +  C   D  S   L     PF IS  N    + C+N+    +T  Q     + C + ++    A ++C  +  C       L          K+   K+ C   V+F+   T SG+L + PE         +E+ W L           CK                      +P  C D+    C     ++ G+R+C+   G       W AI  +  +L    + ++ G  +  +    R + VA+       +    +L    S    +    K+F+  ++  AT+ F+   +LG GG G V+KG+L+DG I AVK++K    + +++  NE+ +L Q+NHR++VK++GCCLE E P+L+YE+I N  LF+HLH    N S+   ++W +RL IA + A+ L+YLH +V   IYH D+KS+NILLD+K  AKV+DFG+SR    + +H+TT  QGT+GY+DPEY  +   T KSDVYSFGV+L+ELLT +K +   R++E   L  Y    +R +RL + +D RIK+     + E + A+  LA  CL    ++RP+M++V  E++
Sbjct:    5 VKRFLVVMLLLRICEYAAASTFPLALRNCSDHCGNVSVPYPFGIGKGCYKNKWFEIVCKSSSDQQPILLLPRIRRA---VTSFNLGDPFSISVYNKFYIQSP--LKHSGCPNRDGYSSSSLNLKGSPFFISENNKFTAVGCNNKAFMNVTGLQIVGCETTCGNEIRSYKGANTSCVGYKCCQMTIPPLLQLQVFDATVEKLEPNKQGCQ--VAFLTQFTLSGSLFTPPELMEYSEYTTIELEWRLDLSYMTSKRVLCKGNTFFEDSYQCSCHNGYEGNPYIPGGCQDI--DECRDPHLNKCGKRKCVNVLGSYRCEKTWPAI--LSGTLSSGLLLLIFGMWL--LCKANRKRKVAKQKRKFFQRNGGLLLQQQTSFLHGSVNRTKVFSSNDLENATDRFNASRILGQGGQGTVYKGMLEDGMIVAVKKSKALKEENLEEFINEIILLSQINHRNVVKILGCCLETEVPILVYEFIPNRNLFDHLH----NPSEDFPMSWEVRLCIACEVADALSYLHSAVSIPIYHRDVKSTNILLDEKHRAKVSDFGISRSVAIDDTHLTTIVQGTIGYVDPEYLQSNHFTGKSDVYSFGVLLIELLTGEKPVSLLRRQEVRMLGAYFLEAMRNDRLHEILDARIKEEC---DREEVLAVAKLARRCLSLNSEHRPTMRDVFIELD 661          

Query:   19 SLLILTMAI--LCCTGHTAAT----------VKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGAL---SSWPEPGVEIMWELPPEPECKLPIDCGDLMN-SVCLAD--RFGQRRCLCKAGFQWDAINAIC-------------HSLVFAAVAMLIGAI-----IGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLA-MTES----SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVSAT 1860
            +LLI T+    L C GH+ A              CP+CG M VPYPLST P CG+Q Y++ C  G L+   L+ SSY+ITSIN +TQR+++RPPGLA++V+C++AD   QG+ LD +LPF+I+S NT++ +NCS  ML    +CS  SLC+ Y+K+N   AS C K PLCC ++T GS  AY IR+    C AY SFV L+ +         WP+ G+E+ W LP EP CK  +DC  L+  S CL D    G +RC CK G +WD +NAIC              ++VFA  A+ +  +     +  +  K   Q V +  H ++ K RE+ML+AN S GKS++IFTG+EIT+ATNNFSKDN++G+GGFGEVFK VL+DGTITA+KRAK  NTKG DQI NEVRILCQVNHRSLV+L+GCC++LE PLLIYE+I NGTLFEHLH  +  T K   LTW  RL IA QTAEGLAYLH +  P IYH D+KSSNILLD+KLNAKV+DFGLSRL  +TE+    SHI T AQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLE++TSKK IDF R+EEDVNLV+Y+  ++ +ERL + IDP +K  A  ++++T++ LG+LASACL+ERRQNRPSMKEVADEIEYII+I++ +V+ T
Sbjct:    9 ALLIPTLLTVWLACAGHSCARHAKAKPPMAGPPRCPNCGPMVVPYPLSTGPTCGDQAYRINCVGGKLYFGALHGSSYVITSINSVTQRIVLRPPGLASSVSCISADVSKQGLELDPHLPFSITSSNTILLLNCSQAMLQAPIDCSPTSLCYSYIKNN---ASPCSKAPLCCTFRTDGSQTAYTIRINGGGCLAYQSFVGLNPNKEVPPPGKKWPDTGLELQWALPKEPVCKTDVDCNLLLGKSKCLPDPTSLGLKRCSCKKGLEWDPVNAICGKCRHGKHCKKKKKTVVFAGAAVAVVGVTLAIAVAVIGTKHSHQKVKKDIHKNIVKEREEMLSAN-STGKSSRIFTGREITKATNNFSKDNLIGTGGFGEVFKAVLEDGTITAIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLGCCVDLELPLLIYEFIPNGTLFEHLHGSSDRTWK--PLTWRRRLQIAYQTAEGLAYLHSAAQPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERLTECIDPLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYIINILSQEVTET 657          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRC-NAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQ----NCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKI-RVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAICH--------------------SLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHF-SLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVS-LTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYII 1830
            ME    SL   T+++L     T    K CP+CG  RVPYPLST  DCG+  Y++RC N G LW DTLN S+  I +I+P  QR ++RPPG   N  C++ D K  GI LD NLPFN+S  NTVI MNC+ + L        NCS NSLCH ++  N  A   CR    CC YKTG S N YK+ R R + CSAY SF+NLD +   +S W EP VEI+WE P EP CK   DC DL+NSVC  D    GQ+RC CK GFQWD++NA+C                      L     A+LI   I   +  ++++ +A +  + S+ K   ++L+ N++     +IFTGKEI +AT+NF+K N+LG GGFGEVFKG LDDGT  AVKRAK GN K + QI NEV+ILCQV+H++LVKL+GCC+ELE P+L+YE++ NGTLFEH++ G          L    RL IA QTA+GL YLH S  P IYH D+KSSNILLD+ L+ KVADFGLSRL +++ SH+TTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVL ELLT KK IDFNR+EEDVNLVV+V+  L+E RLMD IDP I  GA   E+E+MKALG LA  C+ E RQ RP+M+  A EIE I+
Sbjct:    1 MELPWLSLTTFTLSLLIYFSSTTQAFKRCPNCGSTRVPYPLSTGLDCGDPGYRIRCDNYGSLWFDTLNGSTNPIKTIDPSGQRFVLRPPGFEQN-KCVSVDIKYHGIQLDLNLPFNVSCSNTVIIMNCTKDGLDAYSSQGFNCSDNSLCHKFLNANLEARGNCRGVTSCCWYKTGASVNTYKVYRARPDMCSAYQSFMNLDLTI-PVSKWGEPAVEILWEAPREPVCKSQGDCRDLLNSVCSNDSTNLGQKRCFCKKGFQWDSVNAVCEVNRCSKRKSCKRWSNLPLLGGLAGGVGAILIAGFITKTIVSKQNRRIAGNQSWASVRKLHRNLLSINSTG--LDRIFTGKEIVKATDNFAKSNLLGFGGFGEVFKGNLDDGTTVAVKRAKLGNEKSIYQIVNEVQILCQVSHKNLVKLLGCCIELEMPVLVYEFVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLFELLTCKKAIDFNREEEDVNLVVFVRKALKEGRLMDVIDPVIGIGATEKEIESMKALGVLAELCVKETRQCRPTMQVAAKEIENIL 636          

Query:  835 VVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            ++ KRR  N+ RS  F         +  L   +   + +KIF+ KE+ +AT+NFS D VLG GG G V+KG+L DG+I AVKR+K  +   M++  NE+ +L Q+NHR++VKL+GCCLE E P+L+YEYI NG LF+ LH    + S   ++TW +RL IA + A  L Y+H +    I+H DIK++NILLD+K  AKV+DFG SR    + +H+TT   GT GY+DPEY+L+ Q T KSDVYSFGVVL+EL+T +K +   R EE   L  +    ++E R++D ID RIKD +   +LE + A+  LA  CL+ + +NRP+MKEV++E+E I S
Sbjct:  378 LIKKRR--NINRSKKFFKRNGGLLLKQQLTTKDGNVEMSKIFSSKELRKATDNFSIDRVLGQGGQGTVYKGMLVDGSIVAVKRSKVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLH----DESDDYTMTWEVRLRIAIEIAGALTYMHSAASFPIFHRDIKTTNILLDEKYRAKVSDFGTSRSVTLDQTHLTTLVAGTFGYMDPEYFLSSQYTHKSDVYSFGVVLVELITGEKPLSRVRSEEGRGLATHFLEAMKENRVIDIIDIRIKDES---KLEQVMAVAKLARKCLNRKGKNRPNMKEVSNELERIRS 704          

Query:  811 LIGAIIGSVVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            L+  I G + + ++ + + R   F         +  L       +S+KIF+ KE+ +AT+NF+ + VLG GG G V+KG+L DG I AVKR+K  +   +++  NEV +L Q+NHR++VKLMGCCLE E P+L+YE+I NG LF+ LH    + S   ++TW +RL I+ + A  LAYLH +    +YH D+K++NILLD+K  AKV+DFG SR    + +H+TT   GT GYLDPEY+   Q TDKSDVYSFGVVL+EL+T +K     R EE+  LV +    +++ R++D +D RIK+G     LE + A+  LA  CL  + + RP+M+EV+ E+E I S
Sbjct:  323 LVLGIWGLIKFVKKRRKIIRKRMFFKRNGGLLLKQQLTTRGGNVQSSKIFSSKELEKATDNFNMNRVLGQGGQGTVYKGMLVDGRIVAVKRSKVLDEDKVEEFINEVGVLSQINHRNIVKLMGCCLETEVPILVYEHIPNGDLFKRLH----HDSDDYTMTWDVRLRISVEIAGALAYLHSAASTPVYHRDVKTTNILLDEKYRAKVSDFGTSRSINVDQTHLTTLVAGTFGYLDPEYFQTSQFTDKSDVYSFGVVLVELITGEKPFSVMRPEENRGLVSHFNEAMKQNRVLDIVDSRIKEGC---TLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIRS 659          

Query:  811 LIGAIIGSVVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            L+  I G + + ++ + + R   F         +  L       +S+KIF+ KE+ +AT+NF+ + VLG GG G V+KG+L DG I AVKR+K  +   +++  NEV +L Q+NHR++VKLMGCCLE E P+L+YE+I NG LF+ LH    + S   ++TW +RL I+ + A  LAYLH +    +YH D+K++NILLD+K  AKV+DFG SR    + +H+TT   GT GYLDPEY+   Q TDKSDVYSFGVVL+EL+T +K     R EE+  LV +    +++ R++D +D RIK+G     LE + A+  LA  CL  + + RP+M+EV+ E+E I S
Sbjct:  360 LVLGIWGLIKFVKKRRKIIRKRMFFKRNGGLLLKQQLTTRGGNVQSSKIFSSKELEKATDNFNMNRVLGQGGQGTVYKGMLVDGRIVAVKRSKVLDEDKVEEFINEVGVLSQINHRNIVKLMGCCLETEVPILVYEHIPNGDLFKRLH----HDSDDYTMTWDVRLRISVEIAGALAYLHSAASTPVYHRDVKTTNILLDEKYRAKVSDFGTSRSINVDQTHLTTLVAGTFGYLDPEYFQTSQFTDKSDVYSFGVVLVELITGEKPFSVMRPEENRGLVSHFNEAMKQNRVLDIVDSRIKEGC---TLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIRS 696          

Query:  406 QNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIR-----VRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELP---PEPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAI--CHSLVF-----------AAVAMLIGAIIGSVV---YKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMT---ESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            QN SSN L  +    N +  S C K P+ CL   G +     +      V    C  + S ++    S  L       +++ W L        C    DC      V L D     RC C+ GF   A      CH LV+               +L+G ++  V+   Y  R++  A S   S+     + L    +   S   +T KEI +AT++FS  N+LG+G +G V+ G   + +  A+KR K  +T  +DQ+ NE+++L  V+H +LV+L+GCC    +P L+YE++ NGTL++HL     +   +  L+W +RL IA QTA  +A+LH SV P IYH DIKSSNILLD + N+K++DFGLSRL M+   E+SHI+T  QGT GYLDP+Y+ +FQL+DKSDVYSFGVVL+E+++  KVIDF R   +VNL     + +   R++D IDP +          ++  L  LA  CL   R  RP+M E+ +++  I
Sbjct:  113 QNKSSNCLIRNKFVENRLNLSKC-KSPVSCL--DGATTTTADVMSLGDVVNGSGCKYWFSSISQSQVSVNLGR-----LKLDWWLKGSCSNTTCSENADCA----KVKLDDGGLGHRCTCREGFSGKAFTVPGGCHRLVYKRKGLHKLVVLGTAGILVGVLVIVVLIATYFFRNKQSASSERASIA----NRLLCELAGNSSVPFYTYKEIEKATDSFSDKNMLGTGAYGTVYAGEFPNSSCVAIKRLKHKDTTSIDQVVNEIKLLSSVSHPNLVRLLGCCFADGEPFLVYEFMPNGTLYQHLQ----HERGQPPLSWQLRLAIACQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFNSKISDFGLSRLGMSTDFEASHISTAPQGTPGYLDPQYHQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLASLAVDRIGRGRVVDIIDPCLNKEINPKMFASIHNLAELAFRCLSFHRNMRPTMVEITEDLHRI 593          

Query:   94 CGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNC--SNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKI----RVRKERCS---AYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPE---CKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAICH---------------------SLVFAAV--AMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            CG + +PYP   S  C     +  C+A                S+  +T+  I    GL++N T    D      L   N  F  +S N+ +  NC  + +  ++ Q    N L          +  A        L     S N+ K      +R   CS   + ++F ++  ++G    +    V + W L    E   C    DC D    V     +   RC C  GF  D     C                      ++V   V  A L+ A+      KRR     RS H S  +   +   A NS   S   F  KEI +AT+ FS+   LG G +G V++G L +    A+KR +  +++ +DQ+ NE+++L  V+H +LV+L+GCC+E   P+L+YEY+ NGTL EHL        +   L W +RLT+A QTA+ +AYLH S+ P IYH DIKS+NILLD   N+KVADFGLSRL MTESSHI+T  QGT GYLDP+Y+  F L+DKSDVYSFGVVL E++T  KV+DF R   ++NL     + +    + + IDP +        L ++  +  LA  CL      RP+M EVADE+E I
Sbjct:   52 CGGLTLPYPFGFSNGC---SIRFDCSAA-------EKPMIGDFSVQNVTENSIF--VGLSHNCTRKIEDMNP---LFGEN--FAPTSENSFLMENCNRTTDGCSIKQKFLENVL-------KLKSCDATGNISCFSLDSNSSSKNSAKFFSMKTLRNSSCSLLFSSIAFESVGVNAGIALEFER--VRLGWWLKGGCESGTCAANTDCTD----VETPHGYAGHRCSCLDGFHGDGYTNPCQRALPECRGSKLVWRHCRSNLITIVGGTVGGAFLLAALAFFFFCKRRRSTPLRS-HLSAKRLLSEA--AGNS---SVAFFPYKEIEKATDGFSEKQKLGIGAYGTVYRGKLQNDEWVAIKRLRHRDSESLDQVMNEIKLLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHL-----QRDRGSGLPWTLRLTVATQTAKAIAYLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQI 623          

Query:   94 CGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNC--SNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKI----RVRKERCS---AYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPE---CKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAICH---------------------SLVFAAV--AMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            CG + +PYP   S  C     +  C+A                S+  +T+  I    GL++N T    D      L   N  F  +S N+ +  NC  + +  ++ Q    N L          +  A        L     S N+ K      +R   CS   + ++F ++  ++G    +    V + W L    E   C    DC D    V     +   RC C  GF  D     C                      ++V   V  A L+ A+      KRR     RS H S  +   +   A NS   S   F  KEI +AT+ FS+   LG G +G V++G L +    A+KR +  +++ +DQ+ NE+++L  V+H +LV+L+GCC+E   P+L+YEY+ NGTL EHL        +   L W +RLT+A QTA+ +AYLH S+ P IYH DIKS+NILLD   N+KVADFGLSRL MTESSHI+T  QGT GYLDP+Y+  F L+DKSDVYSFGVVL E++T  KV+DF R   ++NL     + +    + + IDP +        L ++  +  LA  CL      RP+M EVADE+E I
Sbjct:   52 CGGLTLPYPFGFSNGC---SIRFDCSAA-------EKPMIGDFSVQNVTENSIF--VGLSHNCTRKIEDMNP---LFGEN--FAPTSENSFLMENCNRTTDGCSIKQKFLENVL-------KLKSCDATGNISCFSLDSNSSSKNSAKFFSMKTLRNSSCSLLFSSIAFESVGVNAGIALEFER--VRLGWWLKGGCESGTCAANTDCTD----VETPHGYAGHRCSCLDGFHGDGYTNPCQRALPECRGSKLVWRHCRSNLITIVGGTVGGAFLLAALAFFFFCKRRRSTPLRS-HLSAKRLLSEA--AGNS---SVAFFPYKEIEKATDGFSEKQKLGIGAYGTVYRGKLQNDEWVAIKRLRHRDSESLDQVMNEIKLLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHL-----QRDRGSGLPWTLRLTVATQTAKAIAYLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQI 623          

Query:  808 MLIGAIIGSVVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIIS 1833
            + IG I     + RR + + +   F         +  L        S ++F  +E+ +AT NFS   +LG GG G V+KG+L DG I AVK++K  +   +++  NEV IL Q+NHR++VKL+GCCLE + P+L+YE+I NG LFEHLH    ++      TW +RL IA   A  L+YLH +    IYH DIKS+NI+LD+K  AKV+DFG SR    + +H+TT   GT+GY+DPEY+ + Q TDKSDVYSFGVVL EL+T +K + F R +E   L  Y    ++E RL D ID RI+DG    +L  + A   +A  CL+ + + RPSM++V+ E+E I S
Sbjct:  371 VFIGGIYWLYKFIRRQRRLNQKKKFFKRNGGLLLQQQLTTTEGNVDSTRVFNSRELEKATENFSLTRILGEGGQGTVYKGMLVDGRIVAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETDVPILVYEFIPNGNLFEHLHD---DSDDYTMTTWEVRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNIMLDEKHRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQSSQFTDKSDVYSFGVVLAELITGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIRDGC---KLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRS 709          

Query:  946 IFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            +F+ +E+ +AT NFS + +LG GG G V+KG+L DG I AVK++K  +   +++  NEV IL Q+NHR++VKL+GCCLE + P+L+YE+I NG LFEHLH       + +  TW +RL IA   A  L+YLH S    IYH D+KS+NI+LD+K  AKV+DFG SR    + +H+TT   GT+GY+DPEY+ + Q TDKSDVYSFGVVL+EL+T +K I F R +E+  L  Y    ++E +L D ID RI+DG     L  + A   +A  CL+ + + RPSM+EV+ E++ I
Sbjct:  434 VFSSRELEKATENFSSNRILGQGGQGTVYKGMLVDGRIVAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETKVPVLVYEFIPNGNLFEHLHD---EFDENIMATWNIRLRIAIDIAGALSYLHSSASSPIYHRDVKSTNIMLDEKYRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQSSQFTDKSDVYSFGVVLVELITGEKSISFLRSQENRTLATYFILAMKENKLFDIIDARIRDGC---MLSQVTATAKVARKCLNLKGRKRPSMREVSMELDSI 721          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQ--NCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTG-GSNNAYKIRVRKERCSAYVSFVNLDTSS-GALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRL---AMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISI 1836
            ME  + S+LIL + +L C+  +A  ++HC +CG   VP+PLST PDCGNQQYK+RC+ G LW D LN SSYLI SINP+ +R++IRP  LAN + C+++DF SQGI L+ NLPF+I++ NT++ +NC NE+L L    +C+  S+CH+Y++ N   A+AC   PLCC +K+  G  +AY I+V    C+AY SFVNLD    G +  WPEPGVEI W LP EP CK+P+DC DL+ S CL D    GQ+RC C AGF+WD IN +C S    AVA+L+  + G +  K+  QN ++ A  +L K R++MLNA +S GKSA+IFTGKEIT+ATNNFSKDN++G+GGFGEVFKG+LDDGT+TA+KRAK GNTKG+DQ+ NEVRILCQVNHRSLV+L+GCC+ELEQP++IYEYI NGTLF+HLH    ++ K  SL+W +RL IA QTAEGL YLH + VP IYH D+KSSNILLD++LNAKV+DFGLSRL   +    SHI TCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLE+LTSKK IDFNR+EE+VNLVVY+KN++ E+RLM+ IDP +K+GA  +ELETMKALGSLA+ACL ++RQNRPSMKEVADEIEYIISI
Sbjct:    1 MEKSILSMLILMVTLLLCSW-SATALQHCGNCGLTPVPFPLSTGPDCGNQQYKLRCSFGKLWFDALNGSSYLIASINPVLRRIVIRPASLANKI-CISSDFHSQGIQLNQNLPFSITNSNTILLLNCKNEILHLKPPIDCAPGSICHNYIQGN---AAACASAPLCCTFKSSTGLQSAYMIKVYDGGCAAYQSFVNLDVKKVGMIKKWPEPGVEIEWALPEEPICKIPVDCKDLLYSKCLPDPISLGQKRCFCDAGFKWDPINGLCQSAAVGAVAVLVMVLGGGLFLKK--QNRSKRAQKNLIKERKEMLNAKHS-GKSARIFTGKEITKATNNFSKDNLIGAGGFGEVFKGILDDGTVTAIKRAKLGNTKGIDQVINEVRILCQVNHRSLVRLLGCCVELEQPIMIYEYIPNGTLFDHLHC--HHSGKWTSLSWQLRLRIAYQTAEGLTYLHSAAVPPIYHRDVKSSNILLDERLNAKVSDFGLSRLVEASENNDSHIFTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEVLTSKKAIDFNREEENVNLVVYIKNVIEEDRLMEVIDPVLKEGASKLELETMKALGSLAAACLHDKRQNRPSMKEVADEIEYIISI 611          

Query:   22 LLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVC--LADRFGQRRCLCKAGFQWDAINAIC-HSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVT 1842
            LL+  + +L C   T +  K+CP+CG   VPYP ST+P CG+ QYK+RCN+G L  DTLNSS Y + SINP  QRL+I+P  L  N TC+ +D+  +GI L+ +LPFNI+S NT++ +NC+  +L    NC+S SLCH YV ++    + C+  P+CC ++ GGS+ A++I VR   C AY SFV+LD S   +  W  PG+ I W LP EP C    DC    NS C   A+  G RRC C  G  WD I  IC H L       L+  +I  ++YKRR +   + A   L + RE++LNA  S  ++AKIFTGK+I +ATNNFSKD +LG+GG+GEVFKG+LDDGT+ AVK AK GNTKG DQ+ NEVRILCQVNHRSLV L+GCC+EL+QP+L+YEYI NG L + L         +  L+W  RL IA  TA+GLAYLH S VP IYH D+KSSNILLD+KLNAKV+DFGLSRLA ++ SHI+TCAQGTLGYLDPEYY  +QLTDKSDVYSFGVVLLELLTS+K +DF R E+D+NL VYV+ ++ EE+LMD IDP +K  A  + LET+KAL  LA +C++E+RQNRPSMKEVA+EIEYI +I T
Sbjct:    8 LLLAAILLLRCAMCTFSA-KNCPNCGTTPVPYPFSTAPACGDPQYKIRCNSGTLLFDTLNSS-YPVMSINPSIQRLVIQPASLLPN-TCVTSDYIYEGISLNESLPFNITSDNTIMFLNCTESLLRSPLNCTSTSLCHVYV-NSTKGEAPCQAAPICCTFRAGGSSTAHRIMVRDTGCRAYTSFVDLD-SVLPVDKWSNPGLAIEWVLPQEPVCGSQADCDG--NSTCGPAANLSGVRRCYCTGGLHWDPIQGICAHGLTSGIGLTLLVIVISVLLYKRRRR--IKEAQERLAREREEILNAGGS--RAAKIFTGKQIKKATNNFSKDRLLGAGGYGEVFKGILDDGTVVAVKCAKLGNTKGTDQVLNEVRILCQVNHRSLVCLLGCCVELQQPILVYEYIENGNLLDRLQ--GLKPDGKSQLSWLHRLQIAHDTADGLAYLHFSAVPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLAHSDLSHISTCAQGTLGYLDPEYYRKYQLTDKSDVYSFGVVLLELLTSQKALDFTRPEDDINLAVYVQRMMEEEKLMDVIDPMLKVKASSLHLETVKALAFLALSCIEEKRQNRPSMKEVAEEIEYITTIAT 604          

Query:   79 KHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGV--LWLDTLNSSSYLITSINPLTQRLIIRP-PGLANNVTCMAADFK-SQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYV-------KHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCL-ADRFGQRRCLCKAGFQWDAINAIC----HSLVFAAVAML-----------IGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRI---KDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIE 1821
            K CP+CG ++VPYPLST   CG+  Y +RC++    L+ D +N SSYL+  I    QR++++P P ++ +  C+  D   S+G+ L+  LPFN++  NT+   NCS  +L    NC+ +SLCH Y+       K+  +  +       CC +  GG  +AY+IR+    C A+ S ++LD    A S W E GVEI W  PPEP C   +DC     S CL A R G  RCLC  G+ WD +   C    H    A +  L            GAII  +  ++  +   ++    L K REDML +++S GK+A++F  KE+ +ATN FS+D +LGSGGFG+V+KG L DGT+ AVK AK GN K   Q+ NEV IL QVNH++LV+L+GCC+E EQPL+IYEYI NGTL++HLH    +T     L W  RL IA QTAE LAYLH      IYH D+KS+NILLDD+ NAKV+DFGLSRLA    SH++TCAQGTLGYLDPEYY N+QLTDKSDVYS+GVVLLELLTS+K IDF+R ++DVNL +YV    +   +M+ +D R+   +  + +  L +++    LA ACL E++ +RPSM+EV  ++E
Sbjct:   33 KTCPNCGSIQVPYPLSTYSTCGDPNYHLRCDSHSQKLYFDAMNGSSYLVLRIMASFQRMVVQPSPWVSASSACVTQDMVVSEGLRLNQTLPFNLTFSNTIFLYNCSPRLLLTPLNCTPSSLCHRYLESSGHVDKNRALKCAGSPDLSPCCTFVAGGMPSAYRIRLHNSGCKAFRSILSLDPEKPA-SQWEE-GVEIQWASPPEPICNSKLDCSG--PSKCLPAGRSGLSRCLCNRGYYWDRVRGTCFRNKHKSKAAGLLGLEVSIGVICFISFGAIIVLITVRKSSKRFNQA---KLDKAREDMLKSSDS-GKNARMFQLKEVKKATNGFSQDRILGSGGFGQVYKGELQDGTVVAVKSAKVGNLKSTQQVLNEVGILSQVNHKNLVRLLGCCVEGEQPLMIYEYISNGTLYDHLHGNGSSTF----LGWRERLRIAWQTAEALAYLHSGTYTPIYHRDVKSTNILLDDEFNAKVSDFGLSRLARPGLSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSYGVVLLELLTSQKAIDFSRDQDDVNLAIYVSQAAKNGAIMEVVDQRLTGTEPSSNV--LNSVQLFSELAFACLREKKADRPSMREVVQQLE 629          

Query:   19 SLLILTMAILCCTGHTAATVKHCPD-CGHMRVPYPLSTSPDC-GNQQYKVRCNAGVLWLDTLNSSS--YLITSINPLTQRL-----IIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCS---------NEMLTLSQNCSS-------------NSLCHDYVKHNPMAASACRKFPLC--CLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPE--PECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWD------------------------AINAI----CHSLVFAAVAMLIGAIIG--------SVVYK--RRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            SLL+L +     T     T   C + CG++ +PYP  T+ DC  N+ +K+ C       +T N S+    I+ IN     +     I+  P +++N +   ++  +  +      PF  S GN    + C+          +++     CS+             NSLC D    N   A A  +  +    L    GS ++   ++         SF+N+ T+  AL  W    + + W +        K  +DC   +    +++  G   C C  G++ +                         +N +    C    +  V +L+  I G        S +YK  ++ +N+     F         +  L++N+ + +  KIFT KE+  AT+ F+++ +LG GG G V+KG+L+DG I AVKR+     + +++  NEV IL Q+NHR++VKL GCCLE E PLL+YE+I NG LF++LH  NF  ++   L+W MRL IA + A  L+YLH +    IYH DIKS+NILLDDK  AKV+DFG SR    + +H+TT  QGT GYLDPEY+ + Q TDKSDVYSFGVVL+ELL+ KK I  +  +E  +L  +   ++ E RL D +D ++K+    +E E M A+ +LA  CL+  R++RP+MKEV+ E+E I
Sbjct:   10 SLLLLPILFQLATAAPPVTKPGCQNRCGNISIPYPFGTAQDCYANEMFKIVCR------ETANESAPRAFISMINMEVLNITDGAAIVNGPIMSSNCSDRQSNLPALNL---TGSPFFFSFGNVFTAVGCNVRALLTGIGRQVVGCDSTCSADSNQKTLLYGQEINSLCAD---GNCCVARAPYRMQVFQPSLDTKNGSEDSSGCKLAFLTDETNFSFLNI-TNPQALQGWRSVPLVLAWMMDYSIWRYDKSTMDCKYFLYESSVSNVSGYE-CSCSNGYEGNPYLGCTDINECKDPNRHSCLGITKCVNTLGSYKCEVNKYWIVPILVVVIAGILSLLAGISWLYKLAKKRKNIELKRKFFKRNGGLLLQQQLSSNHGSVQKTKIFTSKELETATDRFNENRILGQGGQGTVYKGMLEDGRIVAVKRSTIVGEEKLEEFINEVVILSQINHRNVVKLFGCCLETEVPLLVYEFISNGNLFQYLH--NFYQNEDFILSWEMRLQIAIEVAGALSYLHSAASIPIYHRDIKSANILLDDKYRAKVSDFGSSRSMAIDQTHLTTNVQGTFGYLDPEYFQSSQFTDKSDVYSFGVVLVELLSGKKPIISSTSQETRSLATHFIVLMEENRLFDILDVQVKEDC--LEEEIM-AVANLAKRCLNVSRKHRPTMKEVSAELERI 669          

Query:   94 CGHMRVPYPLSTSPDCGNQQ-YKVRCN---AGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVR-----------KERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNS----------VCLADRFGQRRCLCKAGFQWD--------AINAICHSLV----------------------FAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTK--FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEED-VNLVVYVKNILREERLMDAIDPR-IKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            CG +R+PYP      C  ++ +K+ CN   +GVL   T+N +   +  I+     + +  P +  N  C   D ++  + L+ + PF  SS N  I   C N  L ++QN S+   C      N  +  A      CC  +       + + ++           K+  SAY+S      S G +       V++ W +       L +  G   NS          +   ++    +C CK GF+ +        A N   H  +                      F A+ +LIG      V+KR+     +  +F        ++ L++     +  K+F  KE+ +AT++++ +  LG GG G V+KG+L DG I AVK++K  +   + Q  NEV +L Q+NHR++VKL+GCCLE E PLL+YE+I NGTLF+ LH  N    +   LTW MRL IA + A  L YLH +    I+H DIKS+NILLD+K  AKVADFG SR    + +H+TT  QGT GYLDPEY+ + Q TDKSDVYSFGVVL+ELLT +K I F R EE   +L  Y    +    L D +DP+ +K G    E E +  + SLA +CL    + RP+MKEV   +E I
Sbjct:   35 CGDIRIPYPYGMKAGCYQEERFKILCNNYSSGVLPKLTVNGTDLEVRYISVYDSTIQVMFPIVFAN--CSGKD-RNTVVDLEGS-PFVFSSENYFIARGCDNLAL-MTQNQSTIGGCVSICDENSDSMRASCSGIHCCQTRIPSFLKVFNVTMKGLDDGKGSSGEKQCRSAYLSS-GYYYSVGRVRDRDYVPVDLDWGIDKRVFESL-VKNGSFYNSSYTSMCKIVSINSTNQSSTVQCFCKPGFEGNPYLYGFCQASNNCGHCTITQANIQNLIECNWLTCAGVGVGFGALLLLIGLWWLYKVFKRKRSEKLKKKYFKRNGGLLLQEQLSSGEVNVEKIKMFPSKELDKATDHYNVNRTLGQGGQGTVYKGMLADGKIVAVKKSKVIDEGNLRQFINEVVLLSQINHRNVVKLLGCCLETEVPLLVYEFIPNGTLFQFLHDPN----EEFPLTWEMRLRIAAEVAGALFYLHSAASLPIFHRDIKSTNILLDEKYRAKVADFGTSRSVSIDQTHVTTLVQGTFGYLDPEYFQSSQFTDKSDVYSFGVVLVELLTGQKAISFTRSEEQGRSLATYFIMAMESNCLFDILDPQVVKQG----EREEVLMVASLARSCLRLNGKERPTMKEVTMVLERI 656          

Query:   10 RVASLLILTMAIL--CCTGHTAATVKHCPD-CGHMRVPYPLSTSPDCG-NQQYKVRCNAGVLWLDTLNSSSYLITS-INPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNL---PFNISSGNTVIGMNCSNEML-------------TLSQN--------------CSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSN----NAYKIRVRKERCSAYVSFVNLDTSSG-----ALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRFGQRR-CLCKAGFQWDAINAICHSLVFAAVAMLIGAIIGSVVYK--RRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            R  SL+ L + ++    T     T  +C + CG++ +P+P      C  N  + V CN       T +S S    S IN    ++ +    +  N   +++    +G  L  ++   PF  SS N  I M C+N  L             T   N              CS N+ C   +  N    SA        L  T  SN    N  K+    +R  +  +  + +          +  W     +I  E      C  P+     M  +     +     C C  G+  +       +++ AA  +L+  +    +YK  ++ +N+               +  L++++ + +  KIFT KE+ +AT+ F+ + +LG GG G V+KG+L DG I AVK++K  + + +++  NEV IL QVNHR +VKL+GCCLE E PLL+YE+I NG LFE++H    N  +    +W MRL I+ + A  L+YLH +V   IYH DIKS+NILLD+K  AKV+DFG SR    + +H+TT  QGT GY DPEY+ +   T+KSDVYSFGVVL ELL+ +K I + R EE   L  +   ++ E ++ D +D R+         E + A+ +LA  CL+   + RP+M+EVA E+E I
Sbjct:    7 RRVSLIFLLLFLVPEIATVSALMTKPNCTETCGNISIPFPFGIGTGCSMNDWFSVDCNK-----TTADSPSRAFLSRINMEVLKISLGSSRVRVNSPIISSGCSGRGANLSFDMTGSPFVFSSLNIFIAMGCNNRALLNRIEPEIVGCTSTCGANNLTSSSTEGKEKRYCSGNNCCQTRIPSNLQVFSAS-------LGTTEDSNDQGRNQCKVAFIVDRAWSLDNIKSPEAVQDMQHVPVILDWFMYSDDIRVENSEAKNCSPPVQLVSGMWGLSTLTLYSNSTTCSCNLGYDGNPYLPDGCTVLGAATGLLLLLVGIWRLYKLVKKRKNIEMKKKLFKRNGGLLLQQQLSSSDGSIQKTKIFTSKELEKATDRFNDNRILGQGGQGTVYKGMLADGMIVAVKKSKIVDEEKLEEFINEVVILSQVNHRHVVKLLGCCLETEVPLLVYEFIPNGNLFEYIH----NHKEEFEFSWEMRLRISTEVARALSYLHSAVSIMIYHRDIKSTNILLDEKFQAKVSDFGTSRSIAIDQTHLTTHVQGTFGYFDPEYFQSSHFTEKSDVYSFGVVLAELLSGQKPISYERSEERRGLATHFILLMEENKIFDILDERLMRQD---REEEVIAVANLARRCLNLNGRKRPTMREVAIELEQI 643          

Query:  721 GQRRCLCKAGFQWDA--------INAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFRED-------MLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISI 1836
            G   C C  G + D         I  I  S+V   V +L+  I G  +YK  ++   +S       FR++        L++++      K+F+ +E+  AT+ F+ + +LG GG G V+KG+L DG I AVKR+   + + ++   NEV IL Q+N R++V+L+GCCLE E PLL+YE+I NGTL E+LH  N    +   L+W MRL IA +TA  L+YLH +    IYH DIKS+NILLD K  AK+ADFG SR    + +H+TT  QGT GYLDPEY+ + + TDKSDVYSFGVVL ELLT +K I  N  +E  NL  +   ++ E R+ D +D +IK+       E +  + ++A  CL+   + RP+MK+V  E+E II +
Sbjct:  314 GDYECKCPLGMRGDGKRGCRGFGIITIIISVVVGVVGVLLLLIGGWWLYKIMEKR--KSIKLKQKFFRQNGGLLLQQQLSSSDQGISKTKVFSSEELETATDGFNVNRILGQGGQGTVYKGMLADGVIVAVKRSTMVSEENLEGFINEVCILSQINQRNIVRLLGCCLEAEVPLLVYEFIPNGTLSEYLHRQN----EEFPLSWEMRLQIAAETAGALSYLHSAASIPIYHRDIKSTNILLDHKYRAKIADFGTSRSLSVDQTHLTTNVQGTFGYLDPEYFWSSRFTDKSDVYSFGVVLAELLTGQKAILTNESQEHTNLAAHFVLLMEENRIFDIVDAQIKEHC---PKEDVIGVANIAERCLNLNGKKRPTMKQVTSELERIIPL 691          

Query:  679 CGDLMNSVCLADRFGQRRCLCKAGFQWDA-INAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTK---FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEED-VNLVVYVKNILREERLMDAIDPR-IKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            C  + +S+   D+    +C C  GF  +  +   C  +   A+ +LIG      V+KR+     +  +F         ++ L++     +  K+F  KE+ +AT++++ +  LG GG G V+KG+L DG I AVK++K  +   + Q  NEV +L Q+NHR++VKL+GCCLE E PLLIYE+I NGTLF+ LH  N    +   LTW MRL IA + AE L YLH +    I+H DIKS+NILLD +  AKVADFG SR    + +H+TT  QGT GYLDPEY+ + Q TDKSDVYSFGVVL+ELLT +K I F R EE   +L  Y   +L    L D +DP+ +K G    + E +  + SLA +CL    + RP+MKEV   +E I
Sbjct:  237 CKKVNSSINSTDQSSTVQCSCYPGFVGNPYLYGYCQGV--GALFLLIGLWWLYKVFKRKRSEKLKKKNFFKRNGGLLLQEQLSSGEVNVEKIKMFPSKELDKATDHYNVNRTLGQGGQGTVYKGMLADGKIVAVKKSKEIDEGNLRQFINEVVLLSQINHRNVVKLLGCCLETELPLLIYEFIPNGTLFQFLHDPN----EEFPLTWEMRLRIAAEVAEALFYLHSAASLPIFHRDIKSTNILLDKEYRAKVADFGTSRSVSIDQTHVTTLVQGTFGYLDPEYFQSSQFTDKSDVYSFGVVLVELLTGQKPISFTRSEEQGRSLATYFIMVLESNCLFDILDPQVVKQG----KREDVLMVASLARSCLRLNGRKRPTMKEVTMALERI 615          

Query:   85 CPD-CGHMRVPYPLSTSPDCGNQQ-YKVRCNAGVLWLDTLNSSSYLIT-------SINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISS-GNTVIGMNCSNEMLTLS---------QNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYK-------IRVRKERCSAYVS-----FVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAI-CHSLVFAAVAMLIGAIIGSVVY-----------KRRDQNVARSAHFSLTK--FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIE 1821
            CPD CG + +PYP  T  DC   + + V CN       T N     I+       +I+  T    ++ P ++ N T      K  G L     PF  S   N  I + C  ++L              C +    + +++ N M +        CC          +K       +   +E C   V      F +  +   AL         + W +    +  + I C    N    ++      C C+ GF+ +    + C  L  A    ++G++I  +V            K+R     +   F        +  L+ ++ + +  KI++ KE+  AT+ F+   +LG GG G V+KG+L DG I AVK++K  + + +++  NEV IL Q+NHR++VKL+GCCLE E P+L+YE+I NG L++++H  N +      L+W MRL IA + A  L+YLH +    IYH DIKS+NILLD+K  A ++DFG SR    + +H+TT  QGT GYLDPEY+ + Q T+KSDVYSFGVVL+ELL+ +K I      E  +L  +   ++ + RL D +D R+K        E + A+G+LA  CL+   +NRP+MKEV  E+E
Sbjct:   33 CPDRCGDITIPYPFGTGKDCYKDEWFAVECNK------TTNPPRAFISRIKMEVLNISVKTATATVKSPVISFNCTGR----KDGGSLDLTGSPFVFSYFRNVFIAVGCDTQVLMSGIEPQVLGCVPTCGNQQSTNVWLQENNMCSGQN-----CCQASIPSLLQVFKPTLVSTNVDQGREACKLAVLVNTTWFASNISDPFALQHKDYVPANLGWVMNIS-DSDISIYCNTYYNESFKSE------CACRRGFEGNPYLELGCKDLCVAVNNAVVGSVIFILVLLFGLWWIYKLVKKRQNKELKKKFFKRNGGLLLQQQLSTSDGSVQKTKIYSSKELEVATDGFNVSRILGEGGQGTVYKGMLTDGRIIAVKKSKVIDEENLEEFINEVFILSQINHRNVVKLLGCCLETEVPILVYEFISNGNLYKYIHVQNDD----FLLSWEMRLRIAIEVAGALSYLHSAASIPIYHRDIKSTNILLDEKYRAIISDFGSSRSIAIDQTHLTTHVQGTFGYLDPEYFQSSQFTEKSDVYSFGVVLVELLSGQKPIFSASPTESRSLATHFIMLMEDNRLFDILDARVKQHC---HNEEVVAVGNLARKCLNLNGKNRPTMKEVTTELE 627          

Query:  334 LPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPP---EPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINA-------------ICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            L +  S  N+++  NCS      S +C  +        H+    +A      C      G +      V   +CS+  S + L + S  +S   E  +E+ W L     +  C    +C +    V L +     RC C  GF  D                 IC  L    +  LI       V+      V + +     +     L    +   S   F  KEI RATN FS+   LG+G +G V+ G L +  + A+K+ K  +T  +D + NE+++L  V+H +LV+L+GCCLE  +P+L+YE++ NGTL +HL     N      L W +RLT+A +TA  +AYLH  V P IYH DIKSSNILLD    +KVADFGLSRL M ESSHI+T  QGT GYLDP+Y+  F L+DKSDVYSFGVVL+E++T++KV+DF+R   +VNL     + +    + + +DP +        L ++ ++  LA  CL   R  RP+M EVA+E+E I
Sbjct:  107 LNYGPSWQNSLLLQNCSKP----SNSCVISRSPFQGELHSKNCEAAKNDNLSCYSLPYSGIDTLSYEGVNSTQCSSVFSSLALGSDSPVVSFQYER-IELEWWLEGHCRDTFCSKNANCSE----VKLQNGTVGFRCHCYDGFAGDGFTTGNGCRRGEPTWLYICLHLFLLFIMRLIAGASLMAVFALLCYFVKKKSTSMRNRSSAKRLLCEAAGNSSVPFFQYKEIERATNGFSEKQRLGTGAYGTVYSGKLHNDDLVAIKKIKQRDTDSLDLVMNEIKLLSSVSHPNLVRLLGCCLEEGEPILVYEFMPNGTLCQHLQRERGN-----GLPWTVRLTVAAETANAIAYLHSVVNPPIYHRDIKSSNILLDYNYRSKVADFGLSRLGMEESSHISTAPQGTPGYLDPQYHQYFHLSDKSDVYSFGVVLVEIITAQKVVDFSRPHSEVNLAALAIDRIGRGCVDEIVDPYLDPDRDAWTLSSIHSVAELAFRCLAFHRDMRPTMMEVAEELEQI 606          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRFGQRRCLCKA---GFQWDAINAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVSAT 1860
            MENR+ SLLILT+++LCCTG   ATV  C DCGH  VPYPLSTSPDCGNQ YKVRC+AG LW D LNSSSYLITSINPLT+RLIIRPPGLANNVTCM+ADFKSQG++LD+NLPFNI+S NTVIGMNCS EMLTLS+NCSSNSLCHDY+KHN MAASAC  F +CCL+KTGGS NAYKI V KERCSAY SFVNLD+ SG L+SWPE GVE+M     E      +     +  V L     Q   LC +   G   D        L+ AAVAML+GA +  +VYKRR++ +AR+AHFSLTK RED LNANN+ GKSAK+FTGKEITRAT NFSKD VLG+GGFGEVFKGVLDDGTITAVKRA+PGNTKGMDQI NEVRILCQV+HRSLV+LMGCCLELEQPLLIYEYI NGTLFEHLH G +NT+ RVSLTW MRLTIA QTAEGLAYLHDSV PRIYH DIKSSNILLD  LN+KVADFGLSRLA+ ESSHITTCAQG+ GYLDPEYYLNFQLTDKSDVYS+GVVLLELLTSKK IDFNR+EEDVNLVVYVKN L+EERLMDA+DPR+K+GAGIVELETMK   SLA ACLDERRQNRPSMKEVADEI+YII IVTN+ SAT
Sbjct:    1 MENRLVSLLILTVSMLCCTGRNLATVXRCQDCGHTPVPYPLSTSPDCGNQHYKVRCHAGSLWFDALNSSSYLITSINPLTRRLIIRPPGLANNVTCMSADFKSQGLILDDNLPFNITSSNTVIGMNCSYEMLTLSKNCSSNSLCHDYIKHNAMAASACGCFQICCLFKTGGSTNAYKIXVMKERCSAYESFVNLDSFSGPLNSWPESGVEMMIGFRVEVGATFALHVPIHIXLVILV----QLWLLCTSDTEGKLTDXGXVXYXGLIIAAVAMLLGASLAFIVYKRREKKIARAAHFSLTKSREDXLNANNNTGKSAKLFTGKEITRATKNFSKDXVLGAGGFGEVFKGVLDDGTITAVKRAQPGNTKGMDQILNEVRILCQVSHRSLVRLMGCCLELEQPLLIYEYIPNGTLFEHLH-GXYNTANRVSLTWRMRLTIAHQTAEGLAYLHDSVTPRIYHRDIKSSNILLDKMLNSKVADFGLSRLAVAESSHITTCAQGSFGYLDPEYYLNFQLTDKSDVYSYGVVLLELLTSKKAIDFNREEEDVNLVVYVKNTLKEERLMDAVDPRLKEGAGIVELETMKEFASLALACLDERRQNRPSMKEVADEIQYIIGIVTNEDSAT 618          

Query:   25 LILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRF--GQRRCLCKAGFQWDAINAIC---------------------------------------HSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVT 1842
            L+L+ A+L  +     ++  CPDCG   VPYPLSTSP CG+Q YK+RC+AG L  DTLN+S Y I S++P +QRL++RP     N TC+A D   +G+ L+N+LPFN++S NT++ +NC++ +L    NC+++SLCH Y+       S   K  LCC ++ GGS+ +Y IRVR   CSAY SFVNLD     +  WPEPGVE+ W  P EPEC    DC     S C +D    G RRC C +GF WD +  +C                                         L     A LI A I  ++YKR  +   + A   LTK RED+LNAN   G++AK+FTG EI RATN+FSKD +LG+GG+GEV++G L DGT+ AVK AK GNTKG+DQ+ NEVRILCQVNH+SLV L+GCC+ELEQP+L+YEYI NGTL EHL        K +S  W  RL IA  TAEGLAYLH S VP IYH D+KSSNILLD+KLNAKV+DFGLSRLA T+ SHI+TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDFNR+ +DVNL VY + ++ EERLMD +DP +K+GA  +EL+TMKALG LA  CL+ERRQNRPSMKEV +EIEYI SI T
Sbjct:    7 LLLSAALLLTSAWCVLSLPRCPDCGTTTVPYPLSTSPTCGDQSYKIRCSAGSLLFDTLNNS-YPIESVSPASQRLVLRPSAFLPN-TCIATDIVHEGLQLNNSLPFNVTSSNTILYLNCTDTLLRSPLNCTASSLCHTYINGTGSVGSC--KESLCCTFRAGGSSTSYNIRVRNSGCSAYTSFVNLDPGL-PVDRWPEPGVELQWTSPREPECGTQTDCEG--KSTCRSDPAVAGVRRCFCDSGFTWDPVQGLCVDDSIGSKDRTGLIADIKTYSTFYKLYICITNKKEIETSAGLTCGIGATLIAATIAFLLYKRHRR--IKEAQARLTKEREDILNANG--GRAAKVFTGNEIKRATNSFSKDRLLGAGGYGEVYQGTLVDGTVVAVKIAKIGNTKGIDQVLNEVRILCQVNHKSLVHLLGCCVELEQPILVYEYIENGTLLEHLQARKPGGWKHLS--WMQRLQIALDTAEGLAYLHFSAVPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLAHTDLSHISTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNREADDVNLAVYAQRMMLEERLMDVVDPLLKEGANALELDTMKALGLLALGCLEERRQNRPSMKEVTEEIEYIASIAT 640          

Query:   43 ILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGV--LWLDTLNSSSYLITSINPLTQRLIIRP-PGLANNVTCMAADFK-SQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNP-----MAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCL-ADRFGQRRCLCKAGFQWDAINAICHS------------LVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFS----LTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRI---KDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQV 1851
            IL C  H  ++ K CPDCG M+VPYPLSTSPDCG+  Y + C+     L++  LN S YL+  I    QR++++P P L     C+  D   S+G+ L+ +LPFNI+S NT+   NCS  +L    NC+S+SLCH Y++ +       A     +  LCC +  GG  +AYKIR+    C A+ S ++LD +  A S W E G+EI W    EP C+  +DC     S C      G  RCLC   + WD ++  C              +    ++  + A + ++V       V RS  FS    LTK REDML +N S GKSA++F  K++ +ATN FSKD VLGSGGFGEV+KG L+DGT+ AVK AK GN K  +Q+ NEV IL QVNH++LV+L+G C+E EQPL++YEYI NGTL +HLH G F+T     L W  RL IA QTAE L YLH +    IYH D+KS+NILLD  LNAKVADFGLSRLA    SHI+TCAQGTLGYLDPEYY N+QLTDKSDVYS+GVVLLELLTS+K IDF+R  +DVNL +YV         M+ +D R+   ++ +G + + ++K    L  ACL E++ +RP+MK+V  E+  II ++  QV
Sbjct:   18 ILFCIYHCCSSQKTCPDCGXMKVPYPLSTSPDCGDPDYSLHCDPSTKKLFVHALNGSYYLVLQIMAPYQRMVVQPSPWLPGK--CVTQDLVVSEGLWLNQSLPFNITSSNTIFLFNCSPRLLVSPLNCTSSSLCHRYLESSGHIDTNRALQCENRLNLCCTFVAGGMPSAYKIRLHSSGCKAFRSILHLDINKPA-SQWEE-GLEIQWASALEPICRTQLDCSSA--SKCSPTGSSGVSRCLCNREYYWDHLDGTCSKKKRNTKAGLTLKVSIGVISFFVVAAVTAIV------TVKRSCKFSEQKKLTKAREDMLKSN-SDGKSARMFHLKDVKKATNGFSKDRVLGSGGFGEVYKGELEDGTLVAVKSAKVGNVKSTEQVLNEVGILSQVNHKNLVRLLGYCVEAEQPLMLYEYISNGTLSDHLH-GKFSTF----LDWKTRLRIALQTAEALTYLHSAAHTPIYHRDVKSTNILLDSDLNAKVADFGLSRLACPGLSHISTCAQGTLGYLDPEYYRNYQLTDKSDVYSYGVVLLELLTSQKAIDFSRDHDDVNLAIYVSVRANNGVAMEVVDRRLLSEEEPSGNL-VASVKLFLELGLACLKEKKGDRPAMKDVVQELHCIIQVLDQQV 630          

Query:   43 ILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGV--LWLDTLNSSSYLITSINPLTQRLIIRP-PGLANNVTCMAADFK-SQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNP-----MAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAINAICH------------SLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFS----LTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLH 1245
            I+ C     ++ K CP CG M+VPYPLST+PDCG+  Y + C+     L+ D LN S YL+  I  L QR++++P P L     C+  D   S+G+ L+ +LPFNI+S NT+   NCS  +L    NC+ +SLCH Y++ +       A     +  LCC +  GG  +AYKIR+    C A+ S ++LD +    S W E G+EI W  P EP C+  +DC        +  R     CLC   + WD +   C              +    ++  + A + ++V       V RS  FS    LT+ RED+L +NN  GKSA++F  KE+ +ATN FSKD +LGSGGFGEV+KG L+D T+ AVK AK GN K  + + NEV IL QVNH++LV+L+G C+E EQPL+IYEYI NGTL +HLH
Sbjct:  263 IILCVDFRCSSQKTCPGCGSMKVPYPLSTNPDCGDPNYSLHCDPSSKKLYFDALNGSYYLVLQIMALYQRMVVQPSPWLPGK--CVTQDLVVSEGLWLNQSLPFNITSSNTIFLYNCSPRLLVSPLNCTPSSLCHRYLESSRHIDTNRALQCKNRLNLCCTFVAGGMPSAYKIRLHNSGCKAFRSILHLDINKPP-SQWEE-GLEIQWSPPLEPICRTQLDCSSASKCSPIGSR-SVSHCLCNREYYWDHLLGTCSRKKRNTKAGLSLKVSIGVISFFVVAAVVAIV------TVKRSCKFSKQEKLTRAREDILKSNND-GKSARMFHLKEVKKATNGFSKDRLLGSGGFGEVYKGELEDRTLIAVKSAKVGNIKSTEHVLNEVGILSQVNHKNLVRLLGYCVEAEQPLMIYEYISNGTLSDHLH 676          

Query:   22 LLILTMAILCCTGHTAATVKHCPDC----GHMRVPYPLSTSPDCG-NQQYKVRCNAGVLWLDTLNSSSYLI--TSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNIS-SGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRK-------ERCSAYVSFVNLD-------TSSGALSSWPEPGVEIMWELPPEPECKLPI------------DCGDLMNSVCLADRFGQRRCLCKAGFQWD--------AINAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTK--FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRI-KDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            LL+  M+       + A     PDC    G + +PYP    P+C  ++ + + CN      DT N S   +  T +  L   + +    +         D  S  ++     PF  S S N    + C+N  L    N S+   C  + +    A+S+      CC          +   +         E C  Y   V+           +  + +     V + W +       L              + G  +NS   +++    RC CK G++ +         I A    L+  A A  +  ++     K+R+    R   F      F ++ L++     +  KIF  KE+ +AT++F+ + +LG GG G V+KG+L DG + AV ++K  +   +    NE+ IL Q+NHR++VKL GCCLE   PLL+YEY+ NGTLFE++H  N    +   L W MRL IA + A  L YLH S    IYH DIKS+NILLDDK  AKVADFG SR    + +H+TT  QGT GYLDPEY+ + Q T+KSDVYSFGVVL+ELLTS+K I F R EE  +L  Y    + E+RL D +D RI K+G+     E ++A+  LA  CLD   + RP+MKEVA E+E I
Sbjct:   10 LLLWQMSSALAQSQSLALPVALPDCQAQCGSVTIPYPFGIGPNCYLDEWFSISCN------DTYNPSKPFLNSTKLEVLNVSMELGTVRVNYPAKSTCGDMSSAYVMSLEGGPFVFSQSKNRFTAVGCNNLALMTMVNGSTIGGCLSFCRSGLTASSSTCNGIDCCQTTIPSDLQVFNTTIESVETGEPTEGCK-YAFLVDRQWFENEGLRKASDIQNMDSLPVVLEWRIDRRTYDSLATNKSIAFNNSTVCESGSFVNSTSFSNKNSMVRCSCKRGYEGNPYLPDGCQGIGASLGLLLLLATAWWLYKVV-----KKRNDTKRREKFFKQNGGFFIKEQLSSGEVNVEKIKIFDPKELEKATDHFNVNRILGQGGQGTVYKGMLTDGRLVAVXKSKVIDEGKLRPFINEIVILSQLNHRNVVKLFGCCLETNVPLLVYEYVPNGTLFEYIHEDN----EEFPLLWDMRLRIAIEVAGALFYLHSSASIPIYHRDIKSTNILLDDKYRAKVADFGTSRSISIDQTHVTTLVQGTFGYLDPEYFQSSQFTEKSDVYSFGVVLIELLTSQKPISFTRSEEGRSLATYFILKMEEKRLFDIVDVRITKEGS----KEQIEAVACLARRCLDLNGKRRPTMKEVAMELEGI 636          

Query:  661 CKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAIN------------------AICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTK--FREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISI 1836
            C     C +++ SV          CLC  G   D +                   AI   +    +A+L+G        KRR     R   F        +  L+ +  + ++AKIFT +E+  ATNN+ +  VLG GG+G V++G+L D  + A+K++K  +   ++Q  NEV +L QVNHR++VKL+GCCLE E PLL+YE+I NGTL +H+H    N S    L W MRL IA +TA  LAYLH +    I H D+K++NILLDD   AKVADFG SRL   + + +TT  QGTLGYLDPEY+ + QLT+KSDVYSFGVVL ELLT KK + F+R E + NL +Y  + ++E+RL++ +D  +     I+ ++ ++ +  L   CL  +  +RP+MKEV  E++ +IS+
Sbjct:  304 CSSTATCNNILGSV---------NCLCPKGHDGDGMRNGEGCSPIDKRSTQSLKLAIALGICIGMLALLVGGFWIYWGTKRRKYIQLREKFFQQNGGILLQQQLSCHXGSVETAKIFTAEELKNATNNYDESRVLGQGGYGTVYRGLLSDNKVIAIKKSKICDQSQIEQFINEVIVLSQVNHRNVVKLLGCCLETEVPLLVYEFITNGTLSDHIHDNGQNYSL---LPWEMRLKIAAETAGALAYLHSATSMPIIHRDVKTTNILLDDNYIAKVADFGASRLIPIDQTQLTTLVQGTLGYLDPEYFHSSQLTEKSDVYSFGVVLAELLTGKKALSFDRPESERNLAMYFVSSMKEDRLIEILDDHVNVDEEII-IKQIREVAILTKRCLKVKGDDRPTMKEVTAELDGLISL 702          

Query:    7 NRVASLLILTMAILCCTGHTAATVK--HCPDCGHM--------RVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFP--LCCLYKTGGSNNAYKIR-VRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRFGQRRCLCKAGFQWDAIN--------AICHSLVFAA--------VAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDM----LNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYI 1827
            +R +  LI  + +L  +  TAA  K  +   C H          V YP   SP C   Q ++ C+      + +    + + ++ P    + +  P + N        F+S   L   N  F  +  N+++  NCS          +   +  D+V+       +CR     + CL +    +   +   + +  C      +++ +   +  S     VE+ W +    +C     C      V L +R    +C C  GF  D  N        + C+   + +        V +LIG +I           +        T  R  M    L +  +   S  ++  KEI RATN F++   LG+G FG V+ G L +    A+K+    +T G+DQ+ NE+++L  V+H +LV+L+GCC+E  + +L+YEY+ NGTL EHL        +   L W +RLTIA +TA  +AYLH  + P IYH DIKS+NILLD    +KVADFGLSRL MTESS+++T  QGT GY+DP+Y+ NF L+D+SDVYSFGVVL+E++T+ KV+DF R + DVNL     + + +  L + +DP ++       L ++  +G LA  CL      RPSMKEVA+E+EY+
Sbjct:    7 HRKSLTLITVVTVLILSTSTAAIAKAQNSSSCIHTCGSGKSAKTVRYPFGFSPSC---QIRLNCSEN----NEIRLGKFRVLNVTP--NAVFVNLPAICNR------RFESVIELFGPN--FGPTWNNSLLLQNCSAPQ-------NGCLIPADFVQKQ-FNLESCRSSADNISCLSQPHNQSEVMRFEDLSRTGCKNLFGSISVQSDGESPLSLEFETVELGWWVGGLCDCDPNATC----TRVKLGERTDGYQCRCVDGFDGDGFNHGSGCRRVSKCNPSKYMSGRCGGTTRVGVLIGGVIAGAFIMAGLFFICHFVRRRSTCLRNQMSARRLLSEAAGNSSVPLYPYKEIERATNCFAEKQRLGTGAFGTVYAGKLHNDEWVAIKKINRRDTNGIDQVMNEIKLLSSVSHPNLVRLLGCCIEGGEQILVYEYMPNGTLSEHLQR-----ERGQGLPWTIRLTIASETANAIAYLHSEMNPPIYHRDIKSNNILLDYNYKSKVADFGLSRLGMTESSYVSTAPQGTPGYVDPQYHQNFHLSDRSDVYSFGVVLVEIITAMKVVDFARPQSDVNLAALAIDRIGKGSLDEIVDPFLEPNRDAWTLYSVNKVGELAFRCLAFHSDMRPSMKEVAEELEYV 612          

Query:  721 GQRRCLCKAGFQWDA-------------INAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLT---KFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIE 1821
            G   C C  G+  D              +  I   +    V++L+G+    + YKR      +   F        ++ +     S+ ++AKIFT  E+ +AT N+ +  ++G GGFG V+KG+L DG + A+K++K  +   ++Q  NEV +L Q+NHR++VKL+GCC E E PLL+YE++ +GTLFE++H  N   S + +  W +RL IA +TA  L+YLH +    I H D+KS+NILLD+ L AKV+DFG SRL   +++ ++T  QGTLGYLDPEY    QLT+KSDVYSFGV+L+ELLT  K + F+R EE+ NL +Y  + L+++ L   +D  I   A +   E +K + +LA  CL  + + RP+MKEVA E+E
Sbjct:  337 GNHTCSCHKGYYGDGRIKGEGCTPDPTFVIQIVVGIGVGLVSLLMGSSWLYLGYKRWKLMKLKEKFFKRNGGIMLQQQLSQRQGSSHETAKIFTTGELEKATKNYHETRIIGKGGFGTVYKGILADGRVVAIKKSKMVDQSQIEQFINEVVVLSQINHRNVVKLLGCCFETEVPLLVYEFVTHGTLFEYIH--NTTKSSKFNAPWEIRLRIATETAGVLSYLHSAASVPIIHRDVKSTNILLDENLTAKVSDFGASRLVPMDTAQLSTMVQGTLGYLDPEYLQTSQLTEKSDVYSFGVLLVELLTRXKALSFDRPEEERNLAMYFLSALKDDCLQQVLDDCIVTEANV---EQLKEVSNLAKRCLRVKGEERPTMKEVAMELE 714          

Query:  721 GQRRCLCKAGFQWDA-------------INAICHSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLT---KFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIE 1821
            G   C C  G+  D              +  I   +    V++L+G+    + YKR      +   F        ++ +     S+ ++AKIFT  E+ +AT N+ +  ++G GGFG V+KG+L DG + A+K++K  +   ++Q  NEV +L Q+NHR++VKL+GCC E E PLL+YE++ +GTLFE++H  N   S + +  W +RL IA +TA  L+YLH +    I H D+KS+NILLD+ L AKV+DFG SRL   +++ ++T  QGTLGYLDPEY    QLT+KSDVYSFGV+L+ELLT  K + F+R EE+ NL +Y  + L+++ L   +D  I   A +   E +K + +LA  CL  + + RP+MKEVA E+E
Sbjct:  337 GNHTCSCHKGYYGDGRIKGEGCTPDPTFVIQIVVGIGVGLVSLLMGSSWLYLGYKRWKLMKLKEKFFKRNGGIMLQQQLSQRQGSSHETAKIFTTGELEKATKNYHETRIIGKGGFGTVYKGILADGRVVAIKKSKMVDQSQIEQFINEVVVLSQINHRNVVKLLGCCFETEVPLLVYEFVTHGTLFEYIH--NTTKSSKFNAPWEIRLRIATETAGVLSYLHSAASVPIIHRDVKSTNILLDENLTAKVSDFGASRLVPMDTAQLSTMVQGTLGYLDPEYLQTSQLTEKSDVYSFGVLLVELLTRXKALSFDRPEEERNLAMYFLSALKDDCLXQVLDDCIVTEANV---EQLKEVSNLAKRCLRVKGEERPTMKEVAMELE 714          

Query:  901 EDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGT-ITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIE 1821
            +  L +   + ++ KIFTG+E+ RATNN+    ++G GG+G V+KGVL D   + A+K++K G     +Q  NE+ +L Q+NHR++V+L+GCCLE   PLL+YE+I NGTLFEH+H  N   S   S +W +RL IA +TA  LAYLH S + +I H D+K++NILLDD   AKV+DFG SRL   + + +TT  QGT GYLDPEY+L  QLT+KSDVYSFGVVL+ELLTSK  + F R EE+ NL       + E+RL   +D  I +   I   +T+K + +LA  C+  +  +RP+MKEVA E+E
Sbjct:  490 QQQLASQEGSVEAIKIFTGEELKRATNNYHDSRIVGEGGYGIVYKGVLPDSNKVVAIKKSKIGVPTQKEQFVNELIVLSQINHRNVVRLLGCCLETSVPLLVYEFITNGTLFEHIHHKNGRGS---SFSWELRLKIAAETAGALAYLHSSALMQIIHRDVKATNILLDDNYTAKVSDFGASRLIPLDQNQLTTLVQGTYGYLDPEYFLTNQLTEKSDVYSFGVVLMELLTSKVALSFARPEEERNLASLFVCAMEEDRLNQILDQDIVNDGNI---QTVKHVANLAKGCVRLKXGDRPTMKEVAMELE 791          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR--FGQRRCLCKAGFQWDAINAICHSL---------------------VFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTE---SSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIV 1839
            ME  V  LL+  +A+L CT   A     C DCG   VPYPLST P CG+Q YKVRCNAG LW D L+ SSY+ITSINP T+R+I++P  L  N TC+  D +  G+ LD   P+NI S NT++ MNCSN +L  S NCS NS+CH Y++ N +AA+ACR    CC +KTGG  NAYKI VR E C AY SFVNL TS   +  WPEPG+EI W LP EP CK+P DC  L+NS+CL D    GQRRC CKAGF W  IN +C +L                     V    A+LI   +G +V + R QN+ R A  SL K REDMLNANNS GK AKIF+GKEI RATNNFSKDN +GSGGF EVFKG+LDDGT+TAVKRAK GNTKG DQ+ NEVRILCQVNHR LV+L+GCC+ELEQP++IYEYI NGTLF+HLH    ++ K  +LTW  RL+IA QTAEGLAYLH S VP IYH D+KSSNILLD+KL+AKV+DFGLSRLA+     +SHITTCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLELLTSKK IDFNR+EEDVNLV+Y+K I++EE+LMD IDP +KDGA  V++E++KALG LA+ACLDERRQ+RPSMKE A+EIEYIISI+
Sbjct:    1 MEKNVLPLLLHALALLLCT-RAAMCAPRCGDCGRXPVPYPLSTGPGCGDQSYKVRCNAGTLWFDALSQSSYVITSINPGTRRMIVKPASLLAN-TCITTDIQVGGLQLDRISPYNIPSSNTIMLMNCSNAVLNSSVNCSPNSICHAYIREN-VAAAACRSTXKCCWFKTGGPVNAYKIGVRDEGCMAYQSFVNLATSL-PVKRWPEPGLEIEWALPQEPICKIPKDCSTLLNSMCLPDGAILGQRRCFCKAGFHWGPINGLCQNLKCEKAKSCKHKKKSRTPLLGGVAVVAAILILVPVGILVCRHR-QNLKREAQGSLIKKREDMLNANNS-GKMAKIFSGKEIKRATNNFSKDNFIGSGGFSEVFKGILDDGTVTAVKRAKLGNTKGTDQVLNEVRILCQVNHRCLVRLLGCCVELEQPIMIYEYIPNGTLFDHLH--GHHSRKWPALTWRRRLSIALQTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKLDAKVSDFGLSRLAVVSEANASHITTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVLYIKKIMKEEKLMDVIDPVLKDGASKVDMESVKALGLLAAACLDERRQSRPSMKEAAEEIEYIISII 631          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR--FGQRRCLCKAGFQWDAINAICHSL---------------------VFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTE---SSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIV 1839
            ME  V  LL+  +A+L CT   A     C DCG + VPYPLST P CG+Q YKVRCNAG LW D L+ SSY+ITSINP T+R+I++P  L  N TC+  D +  G+ LD   P+NI S NT++ MNCSN +L  S NCS NS+CH Y++ N +AA ACR    CC +K GG  NAYKI VR E C AY SFVNL TS   +  WPEPG+EI W LP EP CK+P DC  L+NS+CL D    GQRRC CKAGF W  IN +C +L                     V    A+LI   +G +V + R QN+ R A  SL K REDMLNANNS GK AKIF+GKEI RATNNFSKDN +GSGGF EVFKG+LDDGT+TAVKRAK GNTKG DQ+ NEVRILCQVNHR LV+L+GCC+ELEQP++IYEYI NGTLF+HLH    ++ K  +LTW  RL+IA QTAEGLAYLH S VP IYH D+KSSNILLD+KL+AKV+DFGLSRLA+     +SHITTCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLELLTSKK IDFNR+EEDVNLV+Y+K I++EE+LMD IDP +KDGA  V++E++KALG LA+ACLDERRQ+RPSMKE A+EIEYIISI+
Sbjct:    1 MEKNVLPLLLHALALLLCT-RAAMCAPRCGDCGRIPVPYPLSTGPGCGDQSYKVRCNAGTLWFDALSQSSYVITSINPGTRRMIVKPASLLAN-TCITTDIQVGGLQLDRISPYNIPSSNTIMLMNCSNAVLNSSVNCSPNSICHAYIRENVVAA-ACRSTAKCCWFKAGGPVNAYKIGVRDEGCMAYQSFVNLATSL-PVKRWPEPGLEIEWALPQEPICKIPKDCSTLLNSMCLPDGAILGQRRCFCKAGFHWGPINGLCQNLKCEKAKSCKHKKKSRTPLLGGVAVVAAILILVPVGILVCRHR-QNLKREAQGSLIKKREDMLNANNS-GKMAKIFSGKEIKRATNNFSKDNFIGSGGFSEVFKGILDDGTVTAVKRAKLGNTKGTDQVLNEVRILCQVNHRCLVRLLGCCVELEQPIMIYEYIPNGTLFDHLH--GHHSRKWPALTWRRRLSIALQTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKLDAKVSDFGLSRLAVVSEANASHITTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVLYIKKIMKEEKLMDVIDPVLKDGASKVDMESVKALGLLAAACLDERRQSRPSMKEAAEEIEYIISII 631          

Query:    1 MENRVASLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQN----CSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSG-ALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADR--FGQRRCLCKAGFQWDAINAICHSL----------------VFAAVAMLIGAII-----GSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTES---SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVS 1854
            MEN V  + IL +A++  +   A  V+ C +CG + VPYPLST PDCG+Q YK+RC AG LW D +N SSY I +INPL +RLII+PP LANN +C+++DF SQGI LD+NLPFNISS NT++ +NC++ +  L  N    CS  S+CH+Y+K +   A+AC   PLCC ++TGG  N   ++V    CSAY SFVNLD  +  AL+ WPEP VEI W LP EP C+ P+DC +L+ S CLAD   FGQ+RC C AGF+WD IN +C ++                +FA VA+  GAI+     G + Y +  ++  R A  +L K R++MLNA +S GKSA+IFTGKEI +ATNNFSKDN++GSGGFGEVFKG+LDDGTITA+KRAK GNTKG DQ+ NEVRILCQVNHRSLV+L+GCC+ELE P++IYEYI NGTLFEHLH     +SK   L W  RL IA QTAEGLAYLH + +P IYH D+KSSNILLD++LNAKV+DFGLSRL  T     SHI TCAQGTLGYLDPEYY NFQLTDKSDVYSFGVVL+E+LTSKK IDFNR+EEDVNLVVY+K ++ E+R++DAIDP +K+ A  +ELETMKALGSLA+ CLDE+RQNRPSMKEVADEI+YII I + +VS
Sbjct:    1 MENNVLMMSILMVALMSYSP-CAIAVRPCGNCGRLLVPYPLSTRPDCGDQHYKLRCTAGTLWFDGVNGSSYTIKTINPLIRRLIIQPPNLANN-SCISSDFHSQGIQLDHNLPFNISSSNTILLLNCTDSVSHLKLNPPMDCSPASICHNYIKEH---AAACIIAPLCCTFRTGGLQNVDALKVYVGECSAYQSFVNLDLKTVLALNKWPEPEVEIEWMLPQEPVCRTPVDCRELLYSKCLADPIIFGQKRCFCNAGFKWDPINGLCQNVKCRTGKACRKRKKKTALFAGVALAGGAILLVAVTGILFYNQHHRS--RQAQKNLIKERKEMLNAKHS-GKSARIFTGKEIIKATNNFSKDNLIGSGGFGEVFKGILDDGTITAIKRAKLGNTKGTDQVLNEVRILCQVNHRSLVRLLGCCVELELPIMIYEYIPNGTLFEHLHCNQ--SSKWTPLPWQRRLRIAHQTAEGLAYLHSAALPPIYHRDVKSSNILLDERLNAKVSDFGLSRLVETSENNDSHIFTCAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLMEILTSKKAIDFNREEEDVNLVVYMKKMIEEDRILDAIDPVLKESASKLELETMKALGSLAATCLDEKRQNRPSMKEVADEIQYIIGITSERVS 639          

Query:   19 SLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASAC----RKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLADRF--GQRRCLCKAGFQWDAINAICHSL---------------------VFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTG--NFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIV 1839
            SLL+LT  I   +       K CP CG  RVPYPLST+P+CG+  YK+RC  G L+ D++N  SY IT+INP TQR I+ P G  NN TCM+ DF ++GI LD N PFNI+S NTV+ +NCSN + T  +NCS +S+CH YVK N +AA  C         CC  KTGGS  AY+IRVRKERCSAY SF NLD S   +S W  PGVE+ WELP EP C++  DC DL NSVC  +    G R+C+CK G++W ++N IC ++                        A+A L  A+I ++V   R Q +      SL++ R D+LNANNS G+SAKIFT KE+T+AT+NFSK N+LG GGFGEVFKG LDDGTITA+KRAKPGN +G+DQI NEV+ILCQVNHRSLV+L+GCC+EL +PLL+YEY+ NGTLFEHLH    N N+SK + L W  RL IA QTAEG+AYLH++ VPRIYH DIKSSNILLDD L+AKV+DFGLSRL +++++HITTCA+GTLGYLDPEYY+NFQLTDKSDVYSFGVVLLELLTSKK IDFNR+EEDVNLVV +K  LRE RLMD +DP +K G   +ELETMKA G+LA ACLD+RR+NRP+MK++ADEIE II I+
Sbjct:    7 SLLVLTFTISLSSFSFVNAFKRCPTCGQTRVPYPLSTAPNCGDPSYKIRCTGGTLFFDSINGFSYAITAINPTTQRFILHPSGFLNN-TCMSTDFPNKGIWLDTNSPFNITSSNTVVLLNCSNNVFTTPRNCSLSSICHKYVKENDVAAKICGPRSHAPQTCCHIKTGGSVTAYRIRVRKERCSAYFSFPNLDPSL-PVSMW-RPGVELEWELPEEPSCRVNEDCLDLENSVCSPNPMIGGSRKCMCKRGYEWYSVNGICQNIKCEHGRGCKRRNKKTSLIGGTTLFAIATLTTAMITTLVLYLRRQRIKGETEQSLSRAR-DILNANNSGGRSAKIFTMKELTKATSNFSKANLLGFGGFGEVFKGTLDDGTITAIKRAKPGNIRGIDQILNEVKILCQVNHRSLVRLLGCCVELPEPLLVYEYVPNGTLFEHLHHHHHNNNSSKGIRLGWHSRLRIAHQTAEGIAYLHNAAVPRIYHRDIKSSNILLDDNLDAKVSDFGLSRLVVSDATHITTCAKGTLGYLDPEYYVNFQLTDKSDVYSFGVVLLELLTSKKAIDFNREEEDVNLVVLIKRALREGRLMDNVDPMLKSGDSRLELETMKAFGALAIACLDDRRKNRPTMKDIADEIECIIGIL 638          

Query:   19 SLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAIC-HSLVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQV 1851
            +LL+ T A+L C    A     CPDCG+  VPYPLST  DCG+Q+YK+RC+AG L  DTLNSS Y I+SI P  QR +IRP   A N TC+  D  +QGI L+ +LPFN++S NT++ +NC++ +L    NCSS SLCH Y+ +    A+AC   P+CC +K GGS  ++ IRVR   C AY SFVNLD S+  ++ WPEPGVEI W  P EP C    DC D MNS C  D    G  RC CK+G  WD +  +C  SL     A LI A+I  +VY+R  +   + A   L + RE++LNAN   GK AK FTGKEI RATN+FS D +LG+GG+GEV+KG+LDDGTI A+K AK GN KG DQ+ NEV ILCQVNHRSLV+L+GCC+ELEQP+++YE+I NGTL EHL         R SLTW  RL IA  TAEGLAYLH S VP IYH D+KSSNILLD+K+NAKVADFGLSRLA T+ SH++TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDFNR  +DVNL VYV+  + EERLMDAIDP +K+ A  +ELETMKA+G LA  CL+ERRQNRPSMKEV +EI YIISI T +V
Sbjct:    3 NLLLFTAALLLCAV-CAMAANRCPDCGNTSVPYPLSTGADCGDQEYKIRCDAGTLRFDTLNSS-YSISSITPQIQRFVIRPASFAGN-TCVTTDLPNQGIQLNESLPFNVTSSNTILYLNCTDTLLRSPLNCSSISLCHTYI-NGTRDAAACEDAPICCTFKAGGSTTSHSIRVRDAGCRAYRSFVNLDAST-PVNRWPEPGVEIQWVSPREPVCTSQSDCTDGMNSTCGPDPATAGVSRCFCKSGLWWDPVGGLCAQSLTVGIGAALIAAVIAILVYRRHRR--IKEAQDRLAREREEILNANGG-GKFAKNFTGKEIKRATNSFSHDRLLGAGGYGEVYKGILDDGTIVAIKCAKLGNAKGTDQVLNEVGILCQVNHRSLVRLLGCCVELEQPIMVYEFIPNGTLLEHLQ--GQRPGGRGSLTWSHRLRIAHDTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKMNAKVADFGLSRLAHTDMSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNRPADDVNLAVYVQRTVEEERLMDAIDPLLKEQASSLELETMKAMGFLAVGCLEERRQNRPSMKEVTEEIGYIISIATAKV 606          

Query:   46 LCCTGHTAAT----------VKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALS---SWPEPGVEIMWELPPEPECKLPIDCGDLMN-SVCLAD--RFGQRRCLCKAGFQWDAINAIC-------------HSLVFAAVAM-LIGAIIGSVVY----KRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLA-MTES----SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVSAT 1860
            L C GH+ A              CP+CG M VPYPLST P+CG+Q Y++ C  G L+   L+ SSY+ITSIN +TQR+++ PPGLA++V+C++AD   QG+ LD +LPF+I+S NT++ +NCS  ML    +CS  SLC+ Y+K+N   AS C K PLCC ++T GS  AY IR+    C AY SFV L+ +         WP+ G+E+ W LP EP CK  +DC  L+  S CL D    G +RC CK G +WD +NAIC              ++VFA VA+ ++GA +   V     K   Q V +  H ++ K RE+ML+AN S GKS++IFTG+EIT+ATNNFSKDN++G+GGFGEVFK VL+DGTITA+KRAK  NTKG DQI NEVRILCQVNHRSLV+L+GCC++LE PLLIYE+I NGTLFEHLH    +T K   LTW  RL IA QTAEGLAYLH +  P IYH D+KSSNILLDDKLNAKV+DFGLSRL  +TE+    SHI T AQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLE++TSKK IDF+R+EEDVNLV+Y+  ++ +ERL++ IDP +K  A  ++++TM+ LG+LASACL+ERRQNRPSMKEVADEIEYII+I++ +V+ T
Sbjct:   20 LACAGHSCARHAKAKPPMAGPPRCPNCGPMVVPYPLSTGPNCGDQAYRINCVGGKLYFGALHGSSYVITSINSVTQRIVLSPPGLASSVSCISADVSKQGLELDPHLPFSITSSNTILLLNCSQAMLQAPIDCSPTSLCYSYIKNN---ASPCSKAPLCCTFRTDGSQTAYTIRINSGGCLAYQSFVGLNPNKEVPPPGIKWPDTGLELQWALPKEPVCKTDVDCNLLLGKSKCLPDPTSLGLKRCSCKRGLEWDPVNAICGKCRHGKHCKKKKKTVVFAGVAVAVVGATLAIAVAVIATKHSHQKVKKDLHKNIVKEREEMLSAN-STGKSSRIFTGREITKATNNFSKDNLIGTGGFGEVFKAVLEDGTITAIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLGCCVDLELPLLIYEFIPNGTLFEHLHGNPDHTWK--PLTWRRRLQIAYQTAEGLAYLHSAAQPPIYHRDVKSSNILLDDKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFSREEEDVNLVMYINKMMDQERLIECIDPLLKKTASKLDMQTMQQLGNLASACLNERRQNRPSMKEVADEIEYIINILSQEVTET 657          

Query:   19 SLLILTMAI--LCCTGHTAAT----------VKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGAL---SSWPEPGVEIMWELPPEPECKLPIDCGDLMN-SVCLAD--RFGQRRCLCKAGFQWDAINAIC-------------HSLVFAAVAMLIGAI-----IGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLA-MTES----SHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQVSAT 1860
            +LLI T+    L C GH+ A              CP+CG M VPYPLST P CG+Q Y++ C  G L+   L+ SSY+ITSIN +TQR+++RPPGLA++V+C++AD   QG+ LD +LPF+I+S NT++ +NCS  ML    +CS  SLC+ Y+K+N   AS C K PLCC ++T GS  AY IR+    C AY SFV L+ +         WP+ G+E+ W LP EP CK  +DC  L+  S CL D    G +RC CK G +WD +NAIC              ++VFA  A+ +  +     +  +  K   Q V +  H ++ K RE+ML+AN S GKS++IFTG+EIT+ATNNFSKDN++G+GGFGEVFK VL+DGTITA+KRAK  NTKG DQI NEVRILCQVNHRSLV+L+GCC++LE PLLIYE+I NGTLFEHLH  +  T K   LTW  RL IA QTAEGLAYLH +  P IYH D+KSSNILLD+KLNAKV+DFGLSRL  +TE+    SHI T AQGTLGYLDPEYY NFQLTDKSDVYSFGVVLLE++TSKK IDF R+EEDVNLV+Y+  ++ +ERL + IDP +K  A  ++++T++ LG+LASACL+ERRQNRPSMKEVADEIEYII+I++ +V+ T
Sbjct:    9 ALLIPTLLTVWLACAGHSCARHAKAKPPMAGPPRCPNCGPMVVPYPLSTGPTCGDQAYRINCVGGKLYFGALHGSSYVITSINSVTQRIVLRPPGLASSVSCISADVSKQGLELDPHLPFSITSSNTILLLNCSQAMLQAPIDCSPTSLCYSYIKNN---ASPCSKAPLCCTFRTDGSQTAYTIRINGGGCLAYQSFVGLNPNKEVPPPGKKWPDTGLELQWALPKEPVCKTDVDCNLLLGKSKCLPDPTSLGLKRCSCKKGLEWDPVNAICGKCRHGKHCKKKKKTVVFAGAAVAVVGVTLAIAVAVIGTKHSHQKVKKDIHKNIVKEREEMLSAN-STGKSSRIFTGREITKATNNFSKDNLIGTGGFGEVFKAVLEDGTITAIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLGCCVDLELPLLIYEFIPNGTLFEHLHGSSDRTWK--PLTWRRRLQIAYQTAEGLAYLHSAAQPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDPEYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERLTECIDPLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYIINILSQEVTET 657          

Query:   19 SLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAICHS---------------------LVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQV 1851
            +LL+ T A+L C    A     CPDCG+  VPYPLST  DCG+Q+YK+RC+AG L  DTLNSS Y I+SI P  QR +IRP   A N TC+  D  +QGI L+ +LPFN++S NT++ +NC++ +L    NCSS SLCH Y+ +    A+AC   P+CC +K GGS  ++ IRVR   C AY SFVNLD S+  ++ WPEPGVEI W  P EP C    DC D MNS C  D    G  RC CK+G  WD +  +C                       L     A LI A+I  +VY+R  +   + A   L + RE++LNAN   GK AK FTGKEI RATN+FS D +LG+GG+GEV+KG+LDDGTI A+K AK GN KG DQ+ NEV ILCQVNHRSLV+L+GCC+ELEQP+++YE+I NGTL EHL         R SLTW  RL IA  TAEGLAYLH S VP IYH D+KSSNILLD+K+NAKVADFGLSRLA T+ SH++TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDFNR  +DVNL VYV+  + EERLMDAIDP +K+ A  +ELETMKA+G LA  CL+ERRQNRPSMKEV +EI YIISI T +V
Sbjct:    3 NLLLFTAALLLCAV-CAMAANRCPDCGNTSVPYPLSTGADCGDQEYKIRCDAGTLRFDTLNSS-YSISSITPQIQRFVIRPASFAGN-TCVTTDLPNQGIQLNESLPFNVTSSNTILYLNCTDTLLRSPLNCSSISLCHTYI-NGTRDAAACEDAPICCTFKAGGSTTSHSIRVRDAGCRAYRSFVNLDAST-PVNRWPEPGVEIQWVSPREPVCTSQSDCTDGMNSTCGPDPATAGVSRCFCKSGLWWDPVGGLCAQNVTCQDPDGCGSTNKTPLIAGLTVGIGAALIAAVIAILVYRRHRR--IKEAQDRLAREREEILNANGG-GKFAKNFTGKEIKRATNSFSHDRLLGAGGYGEVYKGILDDGTIVAIKCAKLGNAKGTDQVLNEVGILCQVNHRSLVRLLGCCVELEQPIMVYEFIPNGTLLEHLQ--GQRPGGRGSLTWSHRLRIAHDTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKMNAKVADFGLSRLAHTDMSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNRPADDVNLAVYVQRTVEEERLMDAIDPLLKEQASSLELETMKAMGFLAVGCLEERRQNRPSMKEVTEEIGYIISIATAKV 626          

Query:   19 SLLILTMAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKHNPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD--RFGQRRCLCKAGFQWDAINAICHS---------------------LVFAAVAMLIGAIIGSVVYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVTNQV 1851
            +LL+ T A+L C    A     CPDCG+  VPYPLST  DCG+Q+YK+RC+AG L  DTLNSS Y I+SI P  QR +IRP   A N TC+  D  +QGI L+ +LPFN++S NT++ +NC++ +L    NCSS SLCH Y+ +    A+AC   P+CC +K GGS  ++ IRVR   C AY SFVNLD S+  ++ WPEPGVEI W  P EP C    DC D MNS C  D    G  RC CK+G  WD +  +C                       L     A LI A+I  +VY+R  +   + A   L + RE++LNAN   GK AK FTGKEI RATN+FS D +LG+GG+GEV+KG+LDDGTI A+K AK GN KG DQ+ NEV ILCQVNHRSLV+L+GCC+ELEQP+++YE+I NGTL EHL         R SLTW  RL IA  TAEGLAYLH S VP IYH D+KSSNILLD+K+NAKVADFGLSRLA T+ SH++TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDFNR  +DVNL VYV+  + EERLMDAIDP +K+ A  +ELETMKA+G LA  CL+ERRQNRPSMKEV +EI YIISI T +V
Sbjct:    3 NLLLFTAALLLCAV-CAMAANRCPDCGNTSVPYPLSTGADCGDQEYKIRCDAGTLRFDTLNSS-YSISSITPQIQRFVIRPASFAGN-TCVTTDLPNQGIQLNESLPFNVTSSNTILYLNCTDTLLRSPLNCSSISLCHTYI-NGTRDAAACEDAPICCTFKAGGSTTSHSIRVRDAGCRAYRSFVNLDAST-PVNRWPEPGVEIQWVSPREPVCTSQSDCTDGMNSTCGPDPATAGVSRCFCKSGLWWDPVGGLCAQNVTCQDPDGCGSTNKTPLIAGLTVGIGAALIAAVIAILVYRRHRR--IKEAQDRLAREREEILNANGG-GKFAKNFTGKEIKRATNSFSHDRLLGAGGYGEVYKGILDDGTIVAIKCAKLGNAKGTDQVLNEVGILCQVNHRSLVRLLGCCVELEQPIMVYEFIPNGTLLEHLQ--GQRPGGRGSLTWSHRLRIAHDTAEGLAYLHSSAVPPIYHRDVKSSNILLDEKMNAKVADFGLSRLAHTDMSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFNRPADDVNLAVYVQRTVEEERLMDAIDPLLKEQASSLELETMKAMGFLAVGCLEERRQNRPSMKEVTEEIGYIISIATAKV 626          

Query:   37 MAILCCTGHTAATVKHCPDCGHMRVPYPLSTSPDCGNQQYKVRCNAGVLWLDTLNSSSYLITSINPLTQRLIIRPPGLANNVTCMAADFKSQGILLDNNLPFNISSGNTVIGMNCSNEMLTLSQNCSSNSLCHDYVKH----NPMAASACRKFPLCCLYKTGGSNNAYKIRVRKERCSAYVSFVNLDTSSGALSSWPEPGVEIMWELPPEPECKLPIDCGDLMNSVCLAD---RFGQRRCLCKAGFQWDAINAIC---------------HSLVFAAVAMLIGAIIGSV-----VYKRRDQNVARSAHFSLTKFREDMLNANNSAGKSAKIFTGKEITRATNNFSKDNVLGSGGFGEVFKGVLDDGTITAVKRAKPGNTKGMDQIFNEVRILCQVNHRSLVKLMGCCLELEQPLLIYEYIRNGTLFEHLHTGNFNTSKRVSLTWPMRLTIARQTAEGLAYLHDSVVPRIYHCDIKSSNILLDDKLNAKVADFGLSRLAMTESSHITTCAQGTLGYLDPEYYLNFQLTDKSDVYSFGVVLLELLTSKKVIDFNRQEEDVNLVVYVKNILREERLMDAIDPRIKDGAGIVELETMKALGSLASACLDERRQNRPSMKEVADEIEYIISIVT 1842
            + +L C    A + + C DCG   VPYPLST PDCG+Q YK+RC +  L  DTLN+S Y ITSI+P TQRL I+P     N TC+  D  + G+ L+++LPFNI+S NT++ +NCS  +LT   NCSS SLCH YV      N  A  ACR  P+CC ++ GGS+ +Y IRVR+  C AY SFVNLD SS  +S WP+PG+E+ W  PPEP C    DC    +S C  D     G  RC C +GF WD I A+C               H+ + A +   +G  + +V     VY+R  +   + A   L + RED+L++     K+AK+FTGKEI +ATNNFS+D +LG+GG+GEV+KGVLDDGT  AVK AK GNTKG DQ+ NEVRILCQVNH+ L++++GCC+ELEQPLL+YEY+ NGTL +HL   N     R  LTW  RL++A  TAEGLAYLH S VP IYH D+KSSNILLD++LNAKV+DFGLSRLA  + SH++TCAQGTLGYLDPEYY N+QLTDKSDVYSFGVVLLELLTS+K IDF+R ++DVNL VYV+ ++ EER+MDA+DP +K+GA  ++LETMKALG LA +CL+ERRQNRPSMKEVA+EIEYIISI T
Sbjct:   13 LLLLMCAAAPALSARRCADCGSSPVPYPLSTGPDCGDQSYKIRCTSTQLLFDTLNNS-YPITSISPETQRLTIQPSPFLPN-TCITQDISTIGVQLNSSLPFNITSSNTIVYLNCSETLLTSPLNCSSASLCHAYVNGSSSGNGGAVGACRSAPICCTFRAGGSSTSYMIRVRESGCRAYRSFVNLD-SSLPVSRWPQPGLELQWVSPPEPVCTAQSDCDS--DSTCTPDPNSNGGISRCFCHSGFHWDPIAALCAQDVTCEDSDGCGSDHTALIAGLTSGLGVAVIAVAIAVFVYRRHKR--IKDAQDRLAREREDILSSGGV--KNAKLFTGKEIRKATNNFSRDRLLGAGGYGEVYKGVLDDGTDVAVKCAKLGNTKGTDQVLNEVRILCQVNHKCLLRILGCCVELEQPLLVYEYVPNGTLSDHLQGPN-----RKLLTWDCRLSVAHATAEGLAYLHFSAVPPIYHRDVKSSNILLDERLNAKVSDFGLSRLAHADLSHVSTCAQGTLGYLDPEYYRNYQLTDKSDVYSFGVVLLELLTSQKAIDFDRAQDDVNLAVYVQRLVEEERIMDAVDPALKEGASSLQLETMKALGFLAVSCLEERRQNRPSMKEVAEEIEYIISIAT 627