ppa025467m, ppa025467m (mRNA) Prunus persica

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M +QGLE++F+GY ++L EC+++ A REGQRVHAHM KTCY PP++LRTRLIV YN C CL DA+RVLDEMP RNVVSWTAMIS YS+RG ASEAL+LF++ML SGT PNEFTFATVLTSC   + GF LGRQIHSL+IKT FESHIFVGSSLLDMYAKAG+I EAR VF+ LPERDVVSCTAIISGYAQLGLDEEAL+LFR+LQREGM SNYVTYASVLTALSGLAALD GRQVH+HVLR +LP YVVLQNSLIDMYSKCG+L+YSRRIFDSMPERTVISWNAMLVGYSKHG+G+E V+LFKLMKEENKV+PDSVTFLAVLSGCSHGGMEDRGLE FYEM   ++G EPE+EHYGCVVDL GRAGRVEEAFEFIKKM FEPTAAIWGSLLGACRVH NV IGEFV  RLL+IE ENAGNYVILSNLYAS GRW+ VR VRELM EKAVIKEPGRSWIELDQ LHTFHASDRSHPR+                AGYVP+L CVLYDVD+EQKEK+L GHSEK+ALAFGLI TP G PVR+IKNLRICVDCHNFAK +S++YGREVSLRDKNRFHHIVGGTCSCGDYW
Sbjct:    1 MGIQGLEVEFQGYDSVLTECISQTAIREGQRVHAHMIKTCYEPPVYLRTRLIVLYNKCRCLGDARRVLDEMPERNVVSWTAMISGYSQRGYASEALHLFVEMLMSGTAPNEFTFATVLTSCTSSS-GFQLGRQIHSLVIKTSFESHIFVGSSLLDMYAKAGKICEARRVFDGLPERDVVSCTAIISGYAQLGLDEEALDLFRRLQREGMRSNYVTYASVLTALSGLAALDHGRQVHSHVLRAKLPFYVVLQNSLIDMYSKCGSLTYSRRIFDSMPERTVISWNAMLVGYSKHGLGREAVELFKLMKEENKVKPDSVTFLAVLSGCSHGGMEDRGLEIFYEMVNQKDGFEPEIEHYGCVVDLFGRAGRVEEAFEFIKKMPFEPTAAIWGSLLGACRVHQNVHIGEFVARRLLEIESENAGNYVILSNLYASAGRWDDVRTVRELMKEKAVIKEPGRSWIELDQTLHTFHASDRSHPRKEEVFAKVRELSIKIKEAGYVPELSCVLYDVDDEQKEKILQGHSEKLALAFGLICTPGGTPVRIIKNLRICVDCHNFAKFLSRVYGREVSLRDKNRFHHIVGGTCSCGDYW 586          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR----------RHRGV--AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            + V+G E     + ++L  C ++    EG+ +H  + K+   P  HL   L+  Y  C   N A +V  E+P R+VVSWTA+I+ +   G  S  L +F QML  G  PN +TF ++L SC+  +   DLG+Q+H+ I+K   + + FVG++L+DMYAK   + +A  +F  L +RD+ + T I++GYAQ G  E+A++ F Q+QREG+  N  T AS L+  S +A LD GRQ+H+  ++      + + ++L+DMY+KCG +  +  +FD +  R  +SWN ++ GYS+HG G + +K F+ M +E  V PD VTF+ VLS CSH G+ + G ++F  +++   G  P +EHY C+VD+LGRAG+  E   FI++M+      IW ++LGAC++H N+E GE    +L ++EPE   NY++LSN++A+ G W+ V NVR LM  + V KEPG SW+E++  +H F + D SHP+           H+ +   GY P+   VL++V + +K+++L  HSE++ALAF L++T     +R+ KNLRIC DCH+F K +S+I  +E+ +RD N FHH   G+CSC ++W
Sbjct:  182 LLVEGFEPNMYTFISILKTCASKGDLNEGKAIHGQVIKSGINPDSHLWNSLVNVYAKCGSANYACKVFGEIPERDVVSWTALITGFVAEGYGS-GLRIFNQMLAEGFNPNMYTFISILRSCSSLS-DVDLGKQVHAQIVKNSLDGNDFVGTALVDMYAKNRFLEDAETIFNRLIKRDLFAWTVIVAGYAQDGQGEKAVKCFIQMQREGVKPNEFTLASSLSGCSRIATLDSGRQLHSMAIKAGQSGDMFVASALVDMYAKCGCVEDAEVVFDGLVSRDTVSWNTIICGYSQHGQGGKALKAFEAMLDEGTV-PDEVTFIGVLSACSHMGLIEEGKKHFNSLSK-IYGITPTIEHYACMVDILGRAGKFHEVESFIEEMKLTSNVLIWETVLGACKMHGNIEFGERAAMKLFELEPEIDSNYILLSNMFAAKGMWDDVTNVRALMSTRGVKKEPGCSWVEVNGQVHVFLSHDGSHPKIREIHLKLQDLHQKLMSVGYTPNTDHVLHNVSDREKQELLFYHSERLALAFALLSTSTRKTIRIFKNLRICGDCHDFMKSISEITNQELVVRDINCFHHFKNGSCSCQNFW 764          

Query:   85 GQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEA 1113
            G+ +HA + K  +   + +    +  Y   + + +  +    M + N+ S   ++S +       +   + +Q+L  G EPN +TF ++L +CA      + G+ IH  +IK+       + +SL+++YAK G    A  VF  +PERDVVS TA+I+G+   G     L +F Q+  EG   N  T+ S+L + S L+ +DLG+QVH  +++  L     +  +L+DMY+K   L  +  IF+ + +R + +W  ++ GY++ G G++ VK F  M+ E  V+P+  T  + LSGCS     D G +  + MA  + G   ++     +VD+  + G VE+A
Sbjct:  109 GESIHACVCKYGFESDILISNAFVTMYMKTQSVENGWQFFKAMMIENLASRNNLLSGFCDTETCDQGPRILIQLLVEGFEPNMYTFISILKTCASKG-DLNEGKAIHGQVIKSGINPDSHLWNSLVNVYAKCGSANYACKVFGEIPERDVVSWTALITGFVAEGYG-SGLRIFNQMLAEGFNPNMYTFISILRSCSSLSDVDLGKQVHAQIVKNSLDGNDFVGTALVDMYAKNRFLEDAETIFNRLIKRDLFAWTVIVAGYAQDGQGEKAVKCFIQMQREG-VKPNEFTLASSLSGCSRIATLDSGRQ-LHSMAI-KAGQSGDMFVASALVDMYAKCGCVEDA 446          

Query:   88 QRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCS 978
            +++   + K    P  HL + L+  Y  CE L  A++VL+EMP+++V  W   +S+ +      EA+ LF  M  +    N+F FA+++ S A        G  IH+ + K  FES I + ++ + MY K   +      F+ +   ++ S   ++SG+      ++   +  QL  EG   N  T+ S+L   +    L+ G+ +H  V++  +     L NSL+++Y+KCG+ +Y+ ++F  +PER V+SW A++ G+   G G   +++F  M  E    P+  TF+++L  CS
Sbjct:    9 KKIIFRVIKNGICPDSHLWSSLVNVYVKCESLQCARQVLEEMPIQDVQQWNQKLSSANSPYPLQEAVQLFYLMRHTRIRLNQFIFASLI-SAAASLGDNHYGESIHACVCKYGFESDILISNAFVTMYMKTQSVENGWQFFKAMMIENLASRNNLLSGFCDTETCDQGPRILIQLLVEGFEPNMYTFISILKTCASKGDLNEGKAIHGQVIKSGINPDSHLWNSLVNVYAKCGSANYACKVFGEIPERDVVSWTALITGFVAEGYGSG-LRIFNQMLAEG-FNPNMYTFISILRSCS 302          

Query:   46 LLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------RHRGVAGYVPDLGCV------LYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            LL      RA  EG   HA + +            L+  Y+ C  +  A+++ DEMPVR++VSW  M+ ++++ G   +AL LF+QM + GT  +EFT ++V+ +CA     F+  +Q+H   +KT  +S++FVG++LLD+YAK G + +A  VFEC+PER  V+ +++++GY Q  L EEAL LF + Q  G+  N  T +S L+A +  AAL  G+QV     +  + S + + +SLIDMY+KCG +  +  +F S+ E+ V+ WNA+L G+S+H    E +  F+ M++   + P+ +T+++VLS CSH G+ ++G +YF  M    N   P + HY C+VD+LGRAG + EA +FI +M F+ TA++WGSLL +CR++ N+E+ E     L +IEP NAGN+V+LSN+YA+  RWE V   R L+ E    KE G+SWIE+   +H+F   +R+HPR      +   + G +  +G        L+DV+E +K+++L  HSEK+AL FG++  P G P+R++KNLRIC DCH+F KL S I  RE+ +RD NRFHH   G CSCG++W
Sbjct:   53 LLQSSARNRAAIEGMACHAQIIRVGLRADTITSNMLMNMYSKCGLVESARKLFDEMPVRSLVSWNTMVGSHTQNGDCEKALVLFMQMQKEGTSCSEFTVSSVVCACAAKCCVFEC-KQLHGFALKTALDSNVFVGTALLDVYAKCGLVKDANLVFECMPERSDVTWSSMVAGYVQNELYEEALVLFHRAQAMGLEHNQFTISSALSACAARAALIEGKQVQAVSCKTGIGSNIFVISSLIDMYAKCGIIEEAYTVFSSVEEKNVVLWNAILSGFSRHVRSLEAMIYFEKMQQMG-ICPNDITYISVLSACSHLGLVEKGRKYFDLMIRVHN-VSPNVLHYSCMVDILGRAGLLHEAKDFIDRMPFDATASMWGSLLASCRIYRNLELAEVAAKHLFEIEPHNAGNHVLLSNIYAANDRWEEVARARNLLKESKAKKERGKSWIEIKHKVHSFMVGERNHPRIVEIYLKLEDLVGEMKKIGYKAKTEHDLHDVEESRKQELLRHHSEKLALTFGIMVLPHGAPIRIMKNLRICGDCHSFMKLASSITEREIIVRDTNRFHHFKNGYCSCGEFW 621          

Query:   13 GLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKT-KFESHIFVGSSLLDMYAKAGRIYEARGVFECLP 522
            GLE       + L+ C  R A  EG++V A   KT     + + + LI  Y  C  + +A  V   +  +NVV W A++S +S+   + EA+  F +M + G  PN+ T+ +VL++C+      + GR+   L+I+      ++   S ++D+  +AG ++EA+   + +P
Sbjct:  244 GLEHNQFTISSALSACAARAALIEGKQVQAVSCKTGIGSNIFVISSLIDMYAKCGIIEEAYTVFSSVEEKNVVLWNAILSGFSRHVRSLEAMIYFEKMQQMGICPNDITYISVLSACSHLGL-VEKGRKYFDLMIRVHNVSPNVLHYSCMVDILGRAGLLHEAKDFIDRMP 413          

Query:   16 LEMKFEGYY-------TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCEC---LNDAQRVLDEMPVRNVVSWTAMISAYSKRG-CASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            L+M+  GY        ++L+ C        G+++H+ + +      + +   L+  Y  C     ++D+++V ++MP  NV+SWTA+I+AY++ G C  EA+ LF +M+     PN F+F++VL +C   +  +  G Q++S  +K    S   VG+SL+ MYA++GR+ +AR  F+ L E+++VS  AI+ GYA+    EEA  LF ++   G+  +  T+AS+L+  + + A+  G Q+H  +L+    S   + N+LI MYS+CGN+  + ++F+ M +R VISW +M+ G++KHG     +++F  M E    +P+ +T++AVLS CSH GM   G ++F  M + E+G  P +EHY C+VDLLGR+G + EA EFI  M     A +W +LLGACRVH N E+G      +L+ EP++   Y++LSNL+AS G+W+ V  +R+ M E+ +IKE G SWIE++  +H FH  + SHP+  +               GY+PD   VL+D++EEQKE+ L  HSEK+A+AFGLI+T +  P+R+ KNLR+C DCH   K +S   GRE+ +RD NRFHHI  G CSC DYW
Sbjct:   45 LDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYAQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYT-GEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETG-TKPNEITYVAVLSACSHVGMISEGQKHFNSMYK-EHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSNLHASAGQWKDVVKIRKSMKERNLIKEAGCSWIEVENRVHRFHVGETSHPQAWQIYQELDQLASKIKEMGYIPDTDFVLHDIEEEQKEQFLFQHSEKIAVAFGLISTSQSKPIRIFKNLRVCGDCHTAIKYISMATGREIVVRDSNRFHHIKNGVCSCNDYW 634          

Query:  190 AQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKA---GRIYEARGVFECLPERDVVSCTAIISGYAQLG-LDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPE-NAGNYVILSNLYASVGR-WEGVRNVRELMVEKAVI 1350
            A +V D+MP RN+V+WT MI+ +++ GCA +A++LFL M  SG  P+ FT+++VL++C        LG+Q+HS +I+      + VG SL+DMYAK    G + ++R VFE +PE +V+S TAII+ YAQ G  D+EA+ELF ++    +  N+ +++SVL A   L+    G QV+++ ++  + S   + NSLI MY++ G +  +R+ FD + E+ ++S+NA++ GY+K+   +E   LF  + +   +   + TF ++LSG +  G   +G +    + +G  G +        ++ +  R G +E AF+   +M  +     W S++     H        +  ++L+   + N   YV + +  + VG   EG ++   +  E  ++
Sbjct:    9 AYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGL-LALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYAQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTG-IGISAFTFASLLSGAASIGAMGKGEQIHGRLLKG--GYKSNQCICNALISMYSRCGNIEAAFQVFNEME-DRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSACSHVGMISEGQKHFNSMYKEHGIV 396          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRE---LPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVI 840
            +A  G+ +    + +LL+   +  A  +G+++H  + K  Y     +   LI  Y+ C  +  A +V +EM  RNV+SWT+MI+ ++K G A+ AL +F +ML +GT+PNE T+  VL++C                       SH+     + +       +Y+  G+   +P  +  +C   + G  + GL  EA+E    +    + ++ + + ++L A       +LGR     +L +E     +Y++L N    +++  G      +I  SM ER +I
Sbjct:  253 IADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSAC-----------------------SHV---GMISEGQKHFNSMYKEHGI---VPRMEHYACMVDLLG--RSGLLVEAMEFINSMP---LMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSN----LHASAGQWKDVVKIRKSMKERNLI 497          

Query:   16 LEMKFEGYY-------TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCEC---LNDAQRVLDEMPVRNVVSWTAMISAYSKRG-CASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            L+M+  GY        ++L+ C        G+++H+ + +      + +   L+  Y  C     ++D+++V ++MP  NV+SWTA+I+AY + G C  EA+ LF +M+     PN F+F++VL +C   +  +  G Q++S  +K    S   VG+SL+ MYA++GR+ +AR  F+ L E+++VS  AI+ GYA+    EEA  LF ++   G+  +  T+AS+L+  + + A+  G Q+H  +L+    S   + N+LI MYS+CGN+  + ++F+ M +R VISW +M+ G++KHG     +++F  M E    +P+ +T++AVLS CSH GM   G ++F  M + E+G  P +EHY C+VDLLGR+G + EA EFI  M     A +W +LLGACRVH N E+G      +L+ EP++   Y++LSNL+AS G+W+ V  +R+ M E+ +IKE G SWIE++  +H FH  + SHP+  +               GY+PD   VL+D++EEQKE+ L  HSEK+A+AFGLI+T +  P+R+ KNLR+C DCH   K +S   GRE+ +RD NRFHHI  G CSC DYW
Sbjct:  238 LDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYT-GEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETG-TKPNEITYVAVLSACSHVGMISEGQKHFNSMYK-EHGIVPRMEHYACMVDLLGRSGLLVEAMEFINSMPLMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSNLHASAGQWKDVVKIRKSMKERNLIKEAGCSWIEVENRVHRFHVGETSHPQAWQIYQELDQLASKIKEMGYIPDTDFVLHDIEEEQKEQFLFQHSEKIAVAFGLISTSQSKPIRIFKNLRVCGDCHTAIKYISMATGREIVVRDSNRFHHIKNGVCSCNDYW 827          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMP-VRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKF-ESHIFVGSSLLDMYAK-AGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKC---GNLSYSRRIFDSMPERTVISWNAMLVGYSKHG-MGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLE-YFYEMAEGENGTEPELEHYGCV----VDLLGRAGRVEEA 1113
            Y  LL  C+  R F+ G+ VH  + ++       +   LI  Y+ C     A+ + + M   R++VSW+AM+S ++      +A+  FL ML  G  PNE+ FA V+ +C+   + + +G  I+  ++KT + E+ + VG  L+DM+ K +G +  A  VF+ +PER++V+ T +I+ +AQLG   +A++LF  ++  G   +  TY+SVL+A + L  L LG+Q+H+ V+R  L   V +  SL+DMY+KC   G++  SR++F+ MPE  V+SW A++  Y + G   KE ++LF  M     +RP+  +F +VL  C +      G + Y Y +  G       +    CV    + +  R+GR+E+A
Sbjct:   47 YSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAW-VGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKM-ISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLG-------IASVNCVGNSLISMYARSGRMEDA 408          

Query:  304 MLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECL-PERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRR-ELPSYVVLQNSLIDMYSK-CGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLE-----------------------YFYEMAEG---------ENGTEPELEHYGCVVDLLGRAGRVE-EAFEFIKKM---RFEPTAAIWGSLLGACRVHSNVEIGEFV---GFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVI 1350
            M +    P+  T++ +L SC      F LG+ +H  ++++  E    V ++L+ +Y+K G    AR +FE +  +RD+VS +A++S +A   ++ +A+  F  +   G   N   +A+V+ A S      +G  ++  V++   L + V +   LIDM+ K  G+L  + ++FD MPER +++W  M+  +++ G  ++ + LF  M+    V PD  T+ +VLS C+  G+   G +                       Y    A+G         E   E  +  +  ++    ++G  + EA E   KM      P    + S+L AC   S+   GE V     +L        GN +I  ++YA  GR E  R   +++ EK ++
Sbjct:   35 MTQQNAPPDLTTYSILLKSCIRFR-NFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYV-PDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLI--SMYARSGRMEDARKAFDILFEKNLV 421          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRE---LPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVI 840
            +A  G+ +    + +LL+   +  A  +G+++H  + K  Y     +   LI  Y+ C  +  A +V +EM  RNV+SWT+MI+ ++K G A+ AL +F +ML +GT+PNE T+  VL++C                       SH+     + +       +Y+  G+   +P  +  +C   + G  + GL  EA+E    +    + ++ + + ++L A       +LGR     +L +E     +Y++L N    +++  G      +I  SM ER +I
Sbjct:  446 IADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSAC-----------------------SHV---GMISEGQKHFNSMYKEHGI---VPRMEHYACMVDLLG--RSGLLVEAMEFINSMP---LMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSN----LHASAGQWKDVVKIRKSMKERNLI 690          

Query:   10 QGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEEN------------------------------KVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHP--RRHRGV----------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +G E+    + T+L   V+      G  +HA + K  +     + T LI  Y+ C  ++ A+ V D +  +++VSWT M++ +++  C  EAL LF QM   G +PN FTFA+V  +C G    FD+G+ +H   +K+++E  ++VG +LLD+Y K+G I +AR  FE +P++DV+  + +I+ YAQ    +EA+E+F Q+++  +  N  T+ASVL A + +  L+LG Q+H HV++  L S V + N+L+D+Y+KCG +  S  +F   P R  ++WN ++VG+ + G G++ ++LF  M E                                 V+PD +TF+ VLS C++ G+ D+G  YF  M + ++G EP +EHY C+V LLGR G +++A + I ++ F+P+  +W +LLGAC +H+++E+G     R+L++EP++   +V+LSN+YA+  RW+ V +VR+ M  K V KEPG SWIE    +H+F   D SHP  R   G+          AGY+P+   VL DV++E+KE++L  HSE++AL+FG+I TP G P+R++KNLRICVDCH   K +SK+  RE+ +RD NRFHH   G CSCGDYW
Sbjct:  133 EGHELNPFVFTTILKLLVSTDCGELGWGIHACIFKLGHESNAFVGTALIDAYSVCGRVDVAREVFDGILYKDMVSWTGMVTCFAENDCFKEALKLFSQMRMVGFKPNNFTFASVFKACLG-LEAFDVGKSVHGCALKSRYELDLYVGVALLDLYTKSGDIDDARRAFEEIPKKDVIPWSFMIARYAQSDQSKEAVEMFFQMRQALVLPNQFTFASVLQACATMEGLNLGNQIHCHVIKIGLHSDVFVSNALMDVYAKCGRMENSMELFAESPHRNDVTWNTVIVGHVQLGDGEKALRLFLNMLEYRVQATEVTYSSALRACASLAALEPGLQIHSLTVKPDKLTFVGVLSACANAGLLDQGQAYFTSMIQ-DHGIEPCIEHYTCMVWLLGRGGHLDKAVKLIDEIPFQPSVMVWRALLGACVIHNDIELGRISAQRVLEMEPQDKATHVLLSNMYATAKRWDNVASVRKNMKRKGVKKEPGLSWIESQGTVHSFTVGDTSHPEVRVINGMLEWLHMKTKKAGYIPNYNVVLLDVEDEEKERLLWVHSERLALSFGIIRTPSGSPIRIMKNLRICVDCHAAIKCISKVVQREIVVRDINRFHHFQEGLCSCGDYW 744          

Query:   19 EMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVL-----TSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVL--RRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFE 1119
            E     Y   L +C+ +     G+ +H  + K      +     L+  Y   + L DA ++ DEMP RN +S+  +I  Y++     EA+ LF+++ R G E N F F T+L     T C    WG      IH+ I K   ES+ FVG++L+D Y+  GR+  AR VF+ +  +D+VS T +++ +A+    +EAL+LF Q++  G   N  T+ASV  A  GL A D+G+ VH   L  R EL  YV +  +L+D+Y+K G++  +RR F+ +P++ VI W+ M+  Y++    KE V++F  M++   V P+  TF +VL  C+   ME   L         + G   ++     ++D+  + GR+E + E
Sbjct:   35 EFNSHAYANALQDCIQKDEPSRGKGLHCEILKRGGCLDLFAWNILLNMYVKSDFLCDASKLFDEMPERNTISFVTLIQGYAESVRFLEAIELFVRLHREGHELNPFVFTTILKLLVSTDCGELGWG------IHACIFKLGHESNAFVGTALIDAYSVCGRVDVAREVFDGILYKDMVSWTGMVTCFAENDCFKEALKLFSQMRMVGFKPNNFTFASVFKACLGLEAFDVGKSVHGCALKSRYELDLYVGV--ALLDLYTKSGDIDDARRAFEEIPKKDVIPWSFMIARYAQSDQSKEAVEMFFQMRQA-LVLPNQFTFASVLQACA--TMEGLNLGNQIHCHVIKIGLHSDVFVSNALMDVYAKCGRMENSME 397          

Query:  256 YSKRGCASEALNLFLQMLR--SGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENG----TEPELEHY--GCVVDLLGRAGRVEE---AFEFIKK------------------------MRFE-------PTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSN----LYASVGRWEGVRNVRELMVE 1338
            +S+RG + ++  L  + +   S +E N   +A  L  C         G+ +H  I+K      +F  + LL+MY K+  + +A  +F+ +PER+ +S   +I GYA+     EA+ELF +L REG   N   + ++L  L      +LG  +H  + +    S   +  +LID YS CG +  +R +FD +  + ++SW  M+  ++++   KE +KLF  M+     +P++ TF +V   C        GLE F ++ +  +G    +  EL+ Y    ++DL  ++G +++   AFE I K                        M F+       P    + S+L AC     + +G  +   +++I      + V +SN    +YA  GR E   N  EL  E
Sbjct:   11 FSRRGFSVQSAKLTQEFVGHVSPSEFNSHAYANALQDCIQKDEP-SRGKGLHCEILKRGGCLDLFAWNILLNMYVKSDFLCDASKLFDEMPERNTISFVTLIQGYAESVRFLEAIELFVRLHREGHELNPFVFTTILKLLVSTDCGELGWGIHACIFKLGHESNAFVGTALIDAYSVCGRVDVAREVFDGILYKDMVSWTGMVTCFAENDCFKEALKLFSQMRMVG-FKPNNFTFASVFKAC-------LGLEAF-DVGKSVHGCALKSRYELDLYVGVALLDLYTKSGDIDDARRAFEEIPKKDVIPWSFMIARYAQSDQSKEAVEMFFQMRQALVLPNQFTFASVLQACATMEGLNLGNQIHCHVIKI---GLHSDVFVSNALMDVYAKCGRME---NSMELFAE 401          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVV-------------------------------SWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGVA------------GYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            + T+L  C   R    G++++  + K  +   + + + L+  Y     + DA+R  DEMP RNVV                               SWT MI+   + G   EAL++F +M  +G   ++FTF +VLT+C G       G+QIH+ +I+T  + ++FVGS+L+DMY+K   I  A  VF+ +P+++V+S TA++ GY Q G  EEA+++F ++QR G+  +  T  SV+++ + LA+L+ G Q H   L   L S++ + N+LI +Y KCG+   S R+F  M  R  +SW A+L GY++ G   E + LF+ M     ++PD VTF+ VLS CS  G+ ++GL+YF  M + E+G  P ++H  C++DLLGRAGR+EEA  FI  M   P    W +LL +CRVH ++EIG++    L+ +EP+N  +YV+LS+LYAS G+W+ V  +R  M +K V KEPG SWI+    +H F A D+S P   +  A            GYVPD+  VL+DV+E +K K+L  HSEK+A+AFGLI  P G+P+RVIKNLR+C DCHN  K +SKI  RE+ +RD  RFH    GTCSCGD+W
Sbjct:  141 FSTMLILCSKFRCVDLGRQINGQILKFGFGSDVFVGSPLVDMYTKLGLIYDAKRYFDEMPERNVVMCNTMITGLMRCGMIEESQRLFCGLKERDSISWTIMITGLMQNGLEREALDMFREMRLAGFAMDQFTFGSVLTAC-GSLLALGEGKQIHAYVIRTDHKDNVFVGSALVDMYSKCRSIKSAETVFKRMPQKNVISWTAMLVGYGQNGFSEEAVKIFFEMQRNGVEPDDFTLGSVISSCANLASLEEGAQFHCRALVSGLISFITVSNALITLYGKCGSTENSHRLFTEMNIRDEVSWTALLAGYAQFGKANETIGLFERMLAHG-LKPDGVTFIGVLSACSRAGLVEKGLQYFESMIK-EHGIMPIVDHCTCIIDLLGRAGRLEEARNFINNMPCHPDVVGWATLLSSCRVHGDMEIGKWAADSLIALEPQNPASYVLLSSLYASKGKWDKVAQLRRGMRDKRVRKEPGYSWIKYKGKVHVFSADDQSSPFLGQIYAELEKLNYKMIEEGYVPDMSSVLHDVEESEKIKMLNHHSEKLAIAFGLIFVPPGLPIRVIKNLRVCGDCHNATKFISKITQREILVRDAVRFHLFKDGTCSCGDFW 743          

Query:  151 LIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGT-EPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSC-------------------------------TAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL 1173
            ++  Y+    L+  Q++ + MP R+ VSW   IS Y+  G  S+A+ ++  ML+      N  TF+T+L  C+      DLGRQI+  I+K  F S +FVGS L+DMY K G IY+A+  F+ +PER+VV C                               T +I+G  Q GL+ EAL++FR+++  G   +  T+ SVLTA   L AL  G+Q+H +V+R +    V + ++L+DMYSKC ++  +  +F  MP++ VISW AMLVGY ++G  +E VK+F  M + N V PD  T  +V+S C++    + G ++        +G    +     ++ L G+ G  E +     +M      + W +LL
Sbjct:   77 ILSVYSKLGLLSQMQQIFNLMPFRDGVSWNLAISGYANYGSCSDAVRVYKLMLKDAAMNLNRITFSTMLILCSKFRC-VDLGRQINGQILKFGFGSDVFVGSPLVDMYTKLGLIYDAKRYFDEMPERNVVMCNTMITGLMRCGMIEESQRLFCGLKERDSISWTIMITGLMQNGLEREALDMFREMRLAGFAMDQFTFGSVLTACGSLLALGEGKQIHAYVIRTDHKDNVFVGSALVDMYSKCRSIKSAETVFKRMPQKNVISWTAMLVGYGQNGFSEEAVKIFFEM-QRNGVEPDDFTLGSVISSCANLASLEEGAQFHCRAL--VSGLISFITVSNALITLYGKCGSTENSHRLFTEMNIRDEVS-WTALL 444          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRE-LPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMP-ERTVISWNAMLVGYSKHG 879
            M + G  M    + ++L  C +  A  EG+++HA++ +T +   + + + L+  Y+ C  +  A+ V   MP +NV+SWTAM+  Y + G + EA+ +F +M R+G EP++FT  +V++SCA  A   + G Q H   + +   S I V ++L+ +Y K G    +  +F  +  RD VS TA+++GYAQ G   E + LF ++   G+  + VT+  VL+A S    ++ G Q    +++   +   V     +ID+  + G L  +R   ++MP    V+ W  +L     HG
Sbjct:  261 MRLAGFAMDQFTFGSVLTACGSLLALGEGKQIHAYVIRTDHKDNVFVGSALVDMYSKCRSIKSAETVFKRMPQKNVISWTAMLVGYGQNGFSEEAVKIFFEMQRNGVEPDDFTLGSVISSCANLA-SLEEGAQFHCRALVSGLISFITVSNALITLYGKCGSTENSHRLFTEMNIRDEVSWTALLAGYAQFGKANETIGLFERMLAHGLKPDGVTFIGVLSACSRAGLVEKGLQYFESMIKEHGIMPIVDHCTCIIDLLGRAGRLEEARNFINNMPCHPDVVGWATLLSSCRVHG 554          

Query:  394 RQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFR--------------------------------QLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEM 1023
            +++H LI+KT  +   F+ ++L+  Y K G +  A  VF+ +P+ ++ S   I+S Y++LGL  +  ++F                                  L+   M  N +T++++L   S    +DLGRQ++  +L+    S V + + L+DMY+K G +  ++R FD MPER V+  N M+ G  + GM +E  +LF  +KE      DS+++  +++G    G+E   L+ F EM
Sbjct:   25 KKLHCLILKTIKQPETFLSNNLITAYYKLGNLAYAHHVFDHIPQPNLFSWNTILSVYSKLGLLSQMQQIFNLMPFRDGVSWNLAISGYANYGSCSDAVRVYKLMLKDAAMNLNRITFSTMLILCSKFRCVDLGRQINGQILKFGFGSDVFVGSPLVDMYTKLGLIYDAKRYFDEMPERNVVMCNTMITGLMRCGMIEESQRLFCGLKER-----DSISWTIMITGLMQNGLEREALDMFREM 261          

Query:  652 SVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKM 1134
            +++TA   L  L     V +H+ +  L S+    N+++ +YSK G LS  ++IF+ MP R  +SWN  + GY+ +G   + V+++KLM ++  +  + +TF  +L  CS     D G +   ++ +   G++  +     +VD+  + G + +A  +  +M
Sbjct:   45 NLITAYYKLGNLAYAHHVFDHIPQPNLFSW----NTILSVYSKLGLLSQMQQIFNLMPFRDGVSWNLAISGYANYGSCSDAVRVYKLMLKDAAMNLNRITFSTMLILCSKFRCVDLGRQINGQILKFGFGSDVFVG--SPLVDMYTKLGLIYDAKRYFDEM 199          

Query:  628 TSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGG 987
            +SNY  YAS+L            +++H  +L+        L N+LI  Y K GNL+Y+  +FD +P+  + SWN +L  YSK G+  ++ ++F LM        D V++   +SG ++ G
Sbjct:    4 SSNY--YASLLKLCCESQNQTQAKKLHCLILKTIKQPETFLSNNLITAYYKLGNLAYAHHVFDHIPQPNLFSWNTILSVYSKLGLLSQMQQIFNLMPFR-----DGVSWNLAISGYANYG 116          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPE-RDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            + + +  C +  +   G+++H    K      + + + L   Y+ C  + DA +V +EMP ++ VSWTAMI  YSK G   EAL  F +M+      ++    + L +C G       GR +HS ++K  FES IFVG++L DMY+KAG +  A  VF    E R+VVS T +I GY +    E+ L +F +L+R+G+  N  T++S++ A +  AAL+ G Q+H  V++        + + L+DMY KCG L  + + FD + + T I+WN+++  + +HG+GK+ +K+F+ M +   V+P+++TF+++L+GCSH G+ + GL+YFY M +   G  P  EHY CV+DLLGRAGR++EA EFI +M FEP A  W S LGACR+H + E+G+    +L+++EP+N+G  V+LSN+YA+  +WE VR+VR  M +  V K PG SW+++    H F A D SHPR+                AGYVP    V  D+D+  KEK+L  HSE++A+AF LI+ P G P+ V KNLR+CVDCH+  K +SK+ GR++ +RD +RFHH   G+CSCGDYW
Sbjct:   44 FSSAIRACASLGSIEMGKQMHCLALKFGIGSELFVGSNLEDMYSKCGAMFDACKVFEEMPCKDEVSWTAMIDGYSKIGEFEEALLAFKKMIDEEVTIDQHVLCSTLGAC-GALKACKFGRSVHSSVVKLGFESDIFVGNALTDMYSKAGDMESASNVFGIDSECRNVVSYTCLIDGYVETEQIEKGLSVFVELRRQGIEPNEFTFSSLIKACANQAALEQGTQLHAQVMKINFDEDPFVSSILVDMYGKCGLLEQAIQAFDEIGDPTEIAWNSLVSVFGQHGLGKDAIKIFERMVDRG-VKPNAITFISLLTGCSHAGLVEEGLDYFYSM-DKTYGVVPGEEHYSCVIDLLGRAGRLKEAKEFINRMPFEPNAFGWCSFLGACRIHGDKEMGKLAAEKLVKLEPKNSGALVLLSNIYANERQWEDVRSVRMRMRDGNVKKLPGYSWVDVGYKTHVFGAEDWSHPRKSAIYEKLDTLLDQIKAAGYVPRTDSVPLDMDDSMKEKLLHRHSERIAVAFALISMPIGKPIIVKKNLRVCVDCHSAIKFISKVTGRKIIVRDNSRFHHFTDGSCSCGDYW 616          

Query:  211 MPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPE-RTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVH 1191
            MP RN+VSWTAMIS  S+    SEA+  F  M   G  P +F F++ + +CA      ++G+Q+H L +K    S +FVGS+L DMY+K G +++A  VFE +P +D VS TA+I GY+++G  EEAL  F+++  E +T +     S L A   L A   GR VH+ V++    S + + N+L DMYSK G++  +  +F    E R V+S+  ++ GY +    ++ + +F  ++ +  + P+  TF +++  C++    ++G +   ++ +     +P +     +VD+ G+ G +E+A +   ++  +PT   W SL+     H
Sbjct:    1 MPQRNLVSWTAMISGLSQNSKFSEAIRTFCGMRICGEVPTQFAFSSAIRACA-SLGSIEMGKQMHCLALKFGIGSELFVGSNLEDMYSKCGAMFDACKVFEEMPCKDEVSWTAMIDGYSKIGEFEEALLAFKKMIDEEVTIDQHVLCSTLGACGALKACKFGRSVHSSVVKLGFESDIFVGNALTDMYSKAGDMESASNVFGIDSECRNVVSYTCLIDGYVETEQIEKGLSVFVELRRQG-IEPNEFTFSSLIKACANQAALEQGTQLHAQVMKINFDEDPFVS--SILVDMYGKCGLLEQAIQAFDEIG-DPTEIAWNSLVSVFGQH 323          

Query:   10 QGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAW---GFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLP 522
            QG+E     + +L+  C N+ A  +G ++HA + K  +     + + L+  Y  C  L  A +  DE+     ++W +++S + + G   +A+ +F +M+  G +PN  TF ++LT C+       G D    +         E H    S ++D+  +AGR+ EA+     +P
Sbjct:  238 QGIEPNEFTFSSLIKACANQAALEQGTQLHAQVMKINFDEDPFVSSILVDMYGKCGLLEQAIQAFDEIGDPTEIAWNSLVSVFGQHGLGKDAIKIFERMVDRGVKPNAITFISLLTGCSHAGLVEEGLDYFYSMDKTYGVVPGEEHY---SCVIDLLGRAGRLKEAKEFINRMP 408          

Query:   58 CVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTK-FESHIFVGSSLLDMYAKAGRIYEAR-------------------------------------------GVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGVA------------GYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            C   + +R G+ V+ +M    +     ++  ++  +  C  ++ A+R  +E+  ++V  W  M+S Y+ +G   +ALN+F +M+  G +PN  T A+ +++C   +     GR+IH   IK +  +S + VG+SL+D YAK   +  AR                                            VF  L  RDVV   +IIS  AQ G    AL+L R++    +  N VT  S L A S LAAL  G+++H  ++R  L +   + NSLIDMY +CG++  SRRIFD MP+R ++SWN M+  Y  HG G + V LF+  +    ++P+ +TF  +LS CSH G+ + G +YF +M + E   +P +E Y C+VDLL RAG+  E  EFI+KM FEP AA+WGSLLGACR+H N ++ E+    L ++EP+++GNYV+++N+Y++ GRWE    +R LM E+ V K PG SWIE+ + LH+F   D SHP   +  A            GYVPD   VL DVDE++KE  L GHSEK+ALAFGLI+T  G P+R+IKNLR+C DCH+  K +SK+  R++ +RD  RFHH V G CSCGDYW
Sbjct:  121 CSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVLEGVKPNSITIASAVSACTNLSL-LRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIKQTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREMNLSNVEVNTVTMVSALPACSKLAALRQGKEIHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLMPQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMG-LKPNHITFTNLLSACSHSGLIEEGWKYF-KMMKTEYAMDPAVEQYACMVDLLSRAGQFNETLEFIEKMPFEPNAAVWGSLLGACRIHCNPDLAEYAARYLFELEPQSSGNYVLMANIYSAAGRWEDAAKIRCLMKERGVTKPPGCSWIEVKRKLHSFVVGDTSHPLMEQISAKMESLYFDIKEIGYVPDTNFVLQDVDEDEKEFSLCGHSEKIALAFGLISTTAGTPLRIIKNLRVCGDCHSATKFISKVEKRDIIMRDNYRFHHFVDGVCSCGDYW 729          

Query:   31 EGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLR-RELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAML--VGYSKHGMGKEVVKLFKLMKEENKV-----RPDSVTFLAVLSGCSHGGMEDRGLEYFYEM 1023
            E Y ++L +C      R G +VHA +          L +RL+  Y    C+ DA+R+ D+M  RNV SWTA++  Y   G   E + LF  M+  G  P+ F F  V  +C+     + +G+ ++  ++   FE +  V  S+LDM+ K GR+  AR  FE +  +DV     ++SGY   G  ++AL +FR++  EG+  N +T AS ++A + L+ L  GR++H + ++  EL S +++ NSL+D Y+KC ++  +RR F  + +  ++SWNAML   G++++G GK  ++ F+ M     V       D V + +++S C+  G     L+   EM
Sbjct:   11 EIYASILQKCRKLYNLRLGFQVHAQLVVNGVDVCEFLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSE-LKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVLEGVKPNSITIASAVSACTNLSLLRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIKQTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREM 348          

Query:  319 TEPNEFT--FATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLE 1008
            T P+E    +A++L  C    +   LG Q+H+ ++    +   F+GS LL++Y + G + +AR +F+ + ER+V S TAI+  Y  LG  EE ++LF  +  EG+  ++  +  V  A S L    +G+ V++++L         ++ S++DM+ KCG +  +RR F+ +  + V  WN M+ GY+  G  K+ + +F+ M  E  V+P+S+T  + +S C++  +   G E
Sbjct:    4 TNPDECIEIYASILQKCRK-LYNLRLGFQVHAQLVVNGVDVCEFLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVLEG-VKPNSITIASAVSACTNLSLLRHGRE 233          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQL----GLDEEALELFRQLQREGMTSNYVTYASVLTA 666
            M +  +E+      + L  C    A R+G+ +H  + +        +   LI  Y  C  +  ++R+ D MP R++VSW  MIS Y   G   +A+NLF Q    G +PN  TF  +L++C+      +  +    +  +   +  +   + ++D+ ++AG+  E     E +P     +    + G  ++     L E A     +L+ +  + NYV  A++ +A
Sbjct:  348 MNLSNVEVNTVTMVSALPACSKLAALRQGKEIHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLMPQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMGLKPNHITFTNLLSACSHSGLIEEGWKYFKMMKTEYAMDPAVEQYACMVDLLSRAGQFNETLEFIEKMPFEPNAAVWGSLLGACRIHCNPDLAEYAARYLFELEPQS-SGNYVLMANIYSA 572          

Query:   85 GQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWG----FDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            G++VH    K+     + +   L+  Y+   C   A+ V ++M   +++SW +MIS+ ++     E++NLF+ +L  G +P+ FT A++  + A  A G     D G+QIH+  IK  F+S + V S +LDMY K G +  A  VF  +   D V+ T++ISG    G +++AL ++ ++++  +  +  T+A+++ A S + AL+ GRQ+H +V++ +  S   +  SL+DMY+KCGN+  + R+F  M  R +  WNAMLVG ++HG  +E V LFK MK    + PD V+F+ +LS CSH G+     EY + M   + G EPE+EHY C+VD LGRAG V+EA + I+ M F+ +A+I  +LLGACR+  +VE G+ V  RL  +EP ++  YV+LSN+YA+  RW+ V + R++M  K V K+PG SWI++  +LH F   DRSHP+            +     GYVPD   VL DV++E+KE+ L  HSEK+A+A+GLI+TP    +RVIKNLR+C DCHN  K +SK++ RE+ LRD NRFHH   G CSCGDYW
Sbjct:  305 GKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKAGFDSDLHVNSGILDMYIKCGDMVNAGIVFNYISAPDDVAWTSMISGCVDNGNEDQALRIYHRMRQSRVMPDEYTFATLIKASSCVTALEQGRQLHANVIKLDCVSDPFVGTSLVDMYAKCGNIEDAYRLFKKMNVRNIALWNAMLVGLAQHGNAEEAVNLFKSMKSHG-IEPDRVSFIGILSACSHAGLTSEAYEYLHSMPN-DYGIEPEIEHYSCLVDALGRAGLVQEADKVIETMPFKASASINRALLGACRIQGDVETGKRVAARLFALEPFDSAAYVLLSNIYAAANRWDDVTDARKMMKRKNVKKDPGFSWIDVKNMLHLFVVDDRSHPQADIIYDKVEEMMKTIREDGYVPDTEFVLLDVEDEEKERSLYYHSEKLAIAYGLISTPASTTIRVIKNLRVCGDCHNAIKYISKVFEREIVLRDANRFHHFRDGVCSCGDYW 865          

Query:   46 LLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCA-GGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSG-----LAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVE--IGEFVGFRLLQIEPENAGNYVILS 1275
            +L  C+N       + VH +  K      + +   L+  Y+ C  + DA+ + D M  R+VV W  M+  Y + G   EA  LF +  RSG  P+EF+   +L  C   G    +LG+Q+H + +K+  +S + V +SL++MY+K G  Y AR VF  +   D++S  ++IS  AQ  L+EE++ LF  L  EG+  ++ T AS+  A +      L  LD G+Q+H H ++    S + + + ++DMY KCG++  +  +F+ +     ++W +M+ G   +G   + ++++  M+ +++V PD  TF  ++   S     ++G +    + + +  ++P +     +VD+  + G +E+A+   KKM      A+W ++L     H N E  +  F   +   IEP+      ILS
Sbjct:  189 VLKLCLNSGCLWAAEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEFHRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEGLKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKAGFDSDLHVNSGILDMYIKCGDMVNAGIVFNYISAPDDVAWTSMISGCVDNGNEDQALRIYHRMR-QSRVMPDEYTFATLIKASSCVTALEQGRQLHANVIKLDCVSDPFVG--TSLVDMYAKCGNIEDAYRLFKKMNVR-NIALWNAMLVGLAQHGNAEEAVNLFKSMKSHGIEPDRVSFIGILS 602          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAY-----SKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSC--AGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTAL--SGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPD-----SVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEA---FEFIKKMRFEPTAAIWGSLLGACRVHSN 1197
            +++LL   ++      G+  HA +  +       L   L+  Y+ C  L+ A++V D  P R++V+W A++ AY     S  G A E L+LF  +  S       T A VL  C  +G  W       +H   IK   E  +FV  +L+++Y+K GR+ +AR +F+ + ERDVV    ++ GY QLGL++EA +LF +  R G+  +  +   +L     +G   L+LG+QVH   ++  L S V + NSL++MYSK G   ++R +F+ M    +ISWN+M+   ++  + +E V LF  +  E  ++PD     S+T       C    + D+G +      +   G + +L     ++D+  + G +  A   F +I      P    W S++  C  + N
Sbjct:   80 WFSLLRTAISTHNLLLGKCTHARIVVSGSAGDHFLSNNLLTMYSKCGSLSSARQVFDTTPERDLVTWNAILGAYAASVDSNDGNAQEGLHLFRLLRASLGSTTRMTLAPVLKLCLNSGCLWA---AEGVHGYAIKIGLEWDVFVSGALVNIYSKCGRMRDARLLFDWMRERDVVLWNMMLKGYVQLGLEKEAFQLFSEFHRSGLRPDEFSVQLILNGCLWAGTDDLELGKQVHGIAVKSGLDSDVSVANSLVNMYSKMGCAYFAREVFNDMKHLDLISWNSMISSCAQSSLEEESVNLFIDLLHEG-LKPDHFTLASITLATAAKACGCLVLLDQGKQIHAHAIKA--GFDSDLHVNSGILDMYIKCGDMVNAGIVFNYIS----APDDVAWTSMISGCVDNGN 473          

Query:   52 NECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEE 588
            + CV   A  +G+++HA++ K   +    + T L+  Y  C  + DA R+  +M VRN+  W AM+   ++ G A EA+NLF  M   G EP+  +F  +L++C+      +    +HS+      E  I   S L+D   +AG + EA  V E +P +   S    + G  ++  D E
Sbjct:  503 SSCVT--ALEQGRQLHANVIKLDCVSDPFVGTSLVDMYAKCGNIEDAYRLFKKMNVRNIALWNAMLVGLAQHGNAEEAVNLFKSMKSHGIEPDRVSFIGILSACSHAGLTSEAYEYLHSMPNDYGIEPEIEHYSCLVDALGRAGLVQEADKVIETMPFKASASINRALLGACRIQGDVE 679          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M +QGLE++F+GY ++L EC+++ A REGQRVHAHM KTCY PP++LRTRLIV YN C CL DA+RVLDEMP RNVVSWTAMIS YS+RG ASEAL+LF++ML SGT PNEFTFATVLTSC   + GF LGRQIHSL+IKT FESHIFVGSSLLDMYAKAG+I EAR VF+ LPERDVVSCTAIISGYAQLGLDEEAL+LFR+LQREGM SNYVTYASVLTALSGLAALD GRQVH+HVLR +LP YVVLQNSLIDMYSKCG+L+YSRRIFDSMPERTVISWNAMLVGYSKHG+G+E V+LFKLMKEENKV+PDSVTFLAVLSGCSHGGMEDRGLE FYEM   ++G EPE+EHYGCVVDL GRAGRVEEAFEFIKKM FEPTAAIWGSLLGACRVH NV IGEFV  RLL+IE ENAGNYVILSNLYAS GRW+ VR VRELM EKAVIKEPGRSWIELDQ LHTFHASDRSHPR+                AGYVP+L CVLYDVD+EQKEK+L GHSEK+ALAFGLI TP G PVR+IKNLRICVDCHNFAK +S++YGREVSLRDKNRFHHIVGGTCSCGDYW
Sbjct:   57 MGIQGLEVEFQGYDSVLTECISQTAIREGQRVHAHMIKTCYEPPVYLRTRLIVLYNKCRCLGDARRVLDEMPERNVVSWTAMISGYSQRGYASEALHLFVEMLMSGTAPNEFTFATVLTSCTSSS-GFQLGRQIHSLVIKTSFESHIFVGSSLLDMYAKAGKICEARRVFDGLPERDVVSCTAIISGYAQLGLDEEALDLFRRLQREGMRSNYVTYASVLTALSGLAALDHGRQVHSHVLRAKLPFYVVLQNSLIDMYSKCGSLTYSRRIFDSMPERTVISWNAMLVGYSKHGLGREAVELFKLMKEENKVKPDSVTFLAVLSGCSHGGMEDRGLEIFYEMVNQKDGFEPEIEHYGCVVDLFGRAGRVEEAFEFIKKMPFEPTAAIWGSLLGACRVHQNVHIGEFVARRLLEIESENAGNYVILSNLYASAGRWDDVRTVRELMKEKAVIKEPGRSWIELDQTLHTFHASDRSHPRKEEVFAKVRELSIKIKEAGYVPELSCVLYDVDDEQKEKILQGHSEKLALAFGLICTPGGTPVRIIKNLRICVDCHNFAKFLSRVYGREVSLRDKNRFHHIVGGTCSCGDYW 642          

Query:  595 ELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEA 1113
            E   ++  +G+   +  Y SVLT      A+  G++VH H+++      V L+  LI +Y+KC  L  +RR+ D MPER V+SW AM+ GYS+ G   E + LF  M       P+  TF  VL+ C+       G +    +   +   E  +     ++D+  +AG++ EA
Sbjct:   52 EALLEMGIQGLEVEFQGYDSVLTECISQTAIREGQRVHAHMIKTCYEPPVYLRTRLIVLYNKCRCLGDARRVLDEMPERNVVSWTAMISGYSQRGYASEALHLFVEMLMSG-TAPNEFTFATVLTSCTSSSGFQLGRQIHSLVI--KTSFESHIFVGSSLLDMYAKAGKICEA 221          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+QG E+KF+GY  LLNECVN+RA REGQRVHAHM KTCYLPP++L TRLI+ Y  CECL  A+ V DEM  RNVVSWTAMIS YS+RG ASEAL+LF+QMLRS TEPNEFTFATVL+SC G + GF+LGRQIHS I K  +E+HIFVGSSLLDMYAKAGRI+EARGVFECLPERDVVSCTAIISGYAQLGLDEEALELF +LQREGM+SNYVTYAS+LTALSGLAALD G+QVH+HVLR ELP YVVLQNSLIDMYSKCGNL+Y+R+IF++MP RTVISWNAMLVGYSKHG G EVVKLFKLM+EENKV+PDSVTFLAVLSGCSHGG+ED+GLE F EM  G +  E  +EHYGCV+DLLGRAGRVEEAFE IKKM FEPTAAIWGSLLGACRVHSN  IGEFVG RLL+IEPENAGNYVILSNLYAS GRWE VRNVRELM+EKAVIKEPGRSWIELDQ +HTF+ASDRSHPRR                +GYVPD  CVLYDVDEEQKEK+LLGHSEK+ALAFGLI+T EGVP+RVIKNLRICVDCHNFAK VSK+YGR+VS+RDKNRFHH+ GG CSCGDYW
Sbjct:    1 MAIQGPEIKFDGYNMLLNECVNKRAVREGQRVHAHMIKTCYLPPVYLSTRLIILYTKCECLGCARHVFDEMRERNVVSWTAMISGYSQRGFASEALHLFVQMLRSDTEPNEFTFATVLSSCTGFS-GFELGRQIHSHIFKRNYENHIFVGSSLLDMYAKAGRIHEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFCRLQREGMSSNYVTYASLLTALSGLAALDHGKQVHSHVLRCELPFYVVLQNSLIDMYSKCGNLNYARKIFNNMPVRTVISWNAMLVGYSKHGKGIEVVKLFKLMREENKVKPDSVTFLAVLSGCSHGGLEDKGLEMFDEMMNGGDEIEAGIEHYGCVIDLLGRAGRVEEAFELIKKMPFEPTAAIWGSLLGACRVHSNTNIGEFVGCRLLEIEPENAGNYVILSNLYASAGRWEDVRNVRELMMEKAVIKEPGRSWIELDQTIHTFYASDRSHPRREEVFLKVRELLVKFKESGYVPDQSCVLYDVDEEQKEKILLGHSEKLALAFGLISTSEGVPLRVIKNLRICVDCHNFAKFVSKVYGRQVSIRDKNRFHHVAGGICSCGDYW 586          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCS 1710
            MA++GL+  F+ Y T+LNEC+ +RA REGQRVHAHM KT YLP ++LRTRLIVFY  C+ L DA+ V D MP RNVVSWTAMISAYS+RG AS+AL+LF+QMLRSGTEPNEFTFATVLTSC G + GF LGRQIHS IIK  +E+H++VGSSLLDMYAK G+I+EARG+F+CLPERDVVSCTAIISGYAQLGLDEEALELFR+LQREGM SNYVTY SVLTALSGLAALD G+QVHNH+LR E+PSYVVLQNSLIDMYSKCGNL+Y+RRIFD++ ERTVISWNAMLVGYSKHG G+EV++LF LM +ENKV+PDSVT LAVLSGCSHGG+ED+G++ FY+M  G+   +P+ +HYGCVVD+LGRAGRVE AFEF+KKM FEP+AAIWG LLGAC VHSN++IGEFVG +LLQIEPENAGNYVILSNLYAS GRWE VR++R LM++KAV KEPGRSWIELDQ+LHTFHASD SHPRR                AGYVPDL CVL+DVDEEQKEK+LL HSEK+AL FGLIATPE VP+RVIKNLRICVDCHNFAK  SKIYGREVSLRDKNRFH IVGG CS
Sbjct:    9 MALRGLDTNFQDYNTVLNECLRKRAIREGQRVHAHMIKTHYLPCVYLRTRLIVFYVKCDSLRDARHVFDVMPERNVVSWTAMISAYSQRGYASQALSLFVQMLRSGTEPNEFTFATVLTSCIGSS-GFVLGRQIHSHIIKLNYEAHVYVGSSLLDMYAKDGKIHEARGIFQCLPERDVVSCTAIISGYAQLGLDEEALELFRRLQREGMQSNYVTYTSVLTALSGLAALDHGKQVHNHLLRSEVPSYVVLQNSLIDMYSKCGNLTYARRIFDTLHERTVISWNAMLVGYSKHGEGREVLELFNLMIDENKVKPDSVTVLAVLSGCSHGGLEDKGMDIFYDMTSGKISVQPDSKHYGCVVDMLGRAGRVEAAFEFVKKMPFEPSAAIWGCLLGACSVHSNLDIGEFVGHQLLQIEPENAGNYVILSNLYASAGRWEDVRSLRNLMLKKAVTKEPGRSWIELDQVLHTFHASDCSHPRREEVSAKVQELSARFKEAGYVPDLSCVLHDVDEEQKEKILLSHSEKLALTFGLIATPESVPIRVIKNLRICVDCHNFAKYTSKIYGREVSLRDKNRFHRIVGGKCS 589          

Query:  595 ELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGC--SHGGMEDRG-----LEYFYEM--------------------AEGENGTEPELEHYGCVVDLLGRA--GRVEEAFEFIKKMR---FEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSN----LYASVGRWEGVRNVRELMVEKAVI 1350
            E    +   G+ +N+  Y +VL       A+  G++VH H+++      V L+  LI  Y KC +L  +R +FD MPER V+SW AM+  YS+ G   + + LF  M       P+  TF  VL+ C  S G +  R      ++  YE                     A G     PE +   C   + G A  G  EEA E  ++++    +     + S+L A    + ++ G+ V   LL+ E     +YV+L N    +Y+  G     R + + + E+ VI
Sbjct:    4 EALLHMALRGLDTNFQDYNTVLNECLRKRAIREGQRVHAHMIKTHYLPCVYLRTRLIVFYVKCDSLRDARHVFDVMPERNVVSWTAMISAYSQRGYASQALSLFVQMLRSG-TEPNEFTFATVLTSCIGSSGFVLGRQIHSHIIKLNYEAHVYVGSSLLDMYAKDGKIHEARGIFQCLPERDVVSCTAIISGYAQLGLDEEALELFRRLQREGMQSNYVTYTSVLTALSGLAALDHGKQVHNHLLRSE---VPSYVVLQNSLIDMYSKCGNLTYARRIFDTLHERTVI 287          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSG---------------------TEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G  MKFE Y  +LNECVN+RAFREGQRVHAHM KT YLP + LRTRLIV Y  C+ L DA  V DEMP RNVVSWTAMISAYS+RG AS+ALNLF   ++                       TEPNEFTFATVLTSC     GF LGRQIHSLIIK  +E H+FVGSSLLDMYAK G+I+EAR VFECLPERDVVSCTAIISGYAQLGLDEEALELFR+LQ EGM SNYVTY  VLTALSGLAALDLG+QVHNHVLR E+PS+VVLQNSLIDMYSKCGNL+YSRRIFD+M ERTVISWNAMLVGYSKHG G+EV+KLF LM+EE KV+PDSVT LAVLSGCSHGG+ED+GL  F +M+ G+   EP++EHYGCVVDLLGR+GRVEEAFEFIKKM FEPTAAIWGSLLGACRVHSNV+IGEF G +LL+IEP NAGNYVILSNLYAS GRWE V ++R+LM++K V KEPGRS IELDQ+LHTFHASDRSHPRR                 GYVPDL CVL+DVDEEQKEK+LLGHSEK+AL+FGLIA+P  VP+RVIKNLRICVDCHNFAK +SK+YGREVSLRDKNRFH IVGG CSC DYW
Sbjct:  234 MALHGFNMKFENYNAILNECVNKRAFREGQRVHAHMIKTRYLPSVFLRTRLIVLYTKCDSLGDAHNVFDEMPERNVVSWTAMISAYSQRGYASQALNLFFADVKISLTGVYAIDKLKLSNPNRPWVCTEPNEFTFATVLTSCTSSL-GFILGRQIHSLIIKLNYEDHVFVGSSLLDMYAKDGKIHEARTVFECLPERDVVSCTAIISGYAQLGLDEEALELFRRLQGEGMKSNYVTYTGVLTALSGLAALDLGKQVHNHVLRSEIPSFVVLQNSLIDMYSKCGNLTYSRRIFDTMYERTVISWNAMLVGYSKHGEGREVLKLFTLMREETKVKPDSVTILAVLSGCSHGGLEDKGLNIFNDMSSGKIEVEPKMEHYGCVVDLLGRSGRVEEAFEFIKKMPFEPTAAIWGSLLGACRVHSNVDIGEFAGQQLLEIEPGNAGNYVILSNLYASAGRWEDVSSLRDLMLKKTVTKEPGRSSIELDQVLHTFHASDRSHPRREEICMKVKELSTSFKEVGYVPDLSCVLHDVDEEQKEKILLGHSEKLALSFGLIASPASVPIRVIKNLRICVDCHNFAKYISKVYGREVSLRDKNRFHRIVGGKCSCEDYW 840          

Query:  607 QLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLR-RELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLF--------------KLMKEENKVR------PDSVTFLAVLSGC--SHGGMEDR-------GLEYFYEMAEGENGTE------------------PELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSN---VEIGEFVGFRLLQIEPENAGNYVILSN----LYASVGRWEGVRNVRELMVEKAVI 1350
            Q+   G    +  Y ++L       A   G++VH H+++ R LPS V L+  LI +Y+KC +L  +  +FD MPER V+SW AM+  YS+ G   + + LF                +K  N  R      P+  TF  VL+ C  S G +  R        L Y   +  G +  +                  PE +   C   + G A  G  EEA E  ++++ E   + + +  G     S    +++G+ V   +L+ E     ++V+L N    +Y+  G     R + + M E+ VI
Sbjct:  233 QMALHGFNMKFENYNAILNECVNKRAFREGQRVHAHMIKTRYLPS-VFLRTRLIVLYTKCDSLGDAHNVFDEMPERNVVSWTAMISAYSQRGYASQALNLFFADVKISLTGVYAIDKLKLSNPNRPWVCTEPNEFTFATVLTSCTSSLGFILGRQIHSLIIKLNYEDHVFVGSSLLDMYAKDGKIHEARTVFECLPERDVVSCTAIISGYAQLGLDEEALELFRRLQGEGMKSNYVTYTGVLTALSGLAALDLGKQVHNHVLRSE---IPSFVVLQNSLIDMYSKCGNLTYSRRIFDTMYERTVI 533          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M + G E+ F  Y  LLN C+++RA REGQRVHAHM KT YLP  +LRTRL++FY  C+CL DA++VLDEMP +NVVSWTAMIS YS+ G +SEAL++F +M+RS  +PNEFTFATVLTSC   + G  LG+QIH LI+K  ++SHIFVGSSLLDMYAKAG+I EAR +FECLPERDVVSCTAII+GYAQLGLDEEALE+F++LQ EGM  NYVTYAS+LTALSGLA LD G+Q H HVLRRELP Y VLQNSLIDMYSKCGNLSY++R+FD+MPERT ISWNAMLVGYSKHG+G+EV++LF+LM++E +V+PD+VT LAVLSGCSHG MED GL  +  M  GE G +P+ EHYGC+VD+LGRAGR++EAFEFIK+M  +PTA + GSLLGACRVH +V+IGE+VG RL++IEPENAGNYVILSNLYAS GRWE V NVR +M++KAV KEPGRSWI+ +Q LH FHA+DR+HPRR   +            AGYVPD+ CVLYDVDEEQKEK+LLGHSEK+AL FGLI T EG+P+RV KNLRICVDCHNFAK+ SK++ REVSLRDKNRFH IV G CSCGDYW
Sbjct:   42 MVMLGPEIGFHCYDALLNACLDKRALREGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALSVFAEMMRSDGKPNEFTFATVLTSCIRAS-GLALGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIEEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFQRLQSEGMRPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYAQRLFDNMPERTAISWNAMLVGYSKHGLGREVLELFRLMRDEKRVKPDAVTLLAVLSGCSHGKMEDTGLSIYDGMVAGEYGIKPDTEHYGCIVDMLGRAGRIDEAFEFIKRMPSKPTAGVLGSLLGACRVHLSVDIGEYVGHRLIEIEPENAGNYVILSNLYASAGRWEDVNNVRAMMMQKAVTKEPGRSWIQHEQTLHYFHANDRTHPRREEVLAKMKEISIKMKQAGYVPDISCVLYDVDEEQKEKMLLGHSEKLALTFGLITTGEGIPIRVFKNLRICVDCHNFAKIFSKVFEREVSLRDKNRFHQIVKGICSCGDYW 627          

Query:  565 AQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLF-KLMKEENKVRPDSVTFLAVLSGC----------------------SHGGMEDRGLEYFYEMAEGENGTE-----PELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFE---PTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIE-PENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVI 1350
            +QL  +    E   ++   G    +  Y ++L A     AL  G++VH H+++        L+  L+  Y KC  L  +R++ D MPE+ V+SW AM+  YS+ G   E + +F ++M+ + K  P+  TF  VL+ C                      SH  +    L+ + +  + E   E     PE +   C   + G A  G  EEA E  ++++ E   P    + SLL A    + ++ G+     +L+ E P  A     L ++Y+  G     + + + M E+  I
Sbjct:   27 SQLCSNGRLQEALLEMVMLGPEIGFHCYDALLNACLDKRALREGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALSVFAEMMRSDGK--PNEFTFATVLTSCIRASGLALGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIEEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFQRLQSEGMRPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYAQRLFDNMPERTAI 320          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +AV G + +F  Y   +  CV R+A  EG++VHAHM K  Y PP++L TRLI+ Y  C  L+DA+ VLD MP RNVVSWTAMIS YS+ G  +EAL LF++MLR+G + NEFT ATVLTSC           Q+HSL++KT FESH+FVGSSLLDMY K+G I EAR VF+ LPERD VSCTAIISGYAQLGLD+EAL+LFRQL   GM  NYVT+ ++LT+LSGLA+L+ G+QVH  +LR+ELP ++VLQNSLIDMYSKCG L YSRR+FD+MP+R+ ISWNAML+GY +HG+G+EVV+LF+ M EE  V+PDSVT LAVLSGCSHGG+ D GL+ F ++   E      + HYGCV+DLLGR+G++++A + I+ M FEPT AIWGSLLGACRVH NV +GE V  +LL +EP NAGNYVILSN+YA+ G W+ V  VR+LM+E  V KEP +SWI LD+++HTFH+S+R HPR+                AG+VPDL CVL+DVD+EQKE++LLGHSEK+A+ FGL+ TP G+ ++V+KNLRICVDCHNFAK VSK+YGRE+SLRDKNRFH +  G C+CGDYW
Sbjct:   13 LAVPGADARFHDYDAAITACVERQALGEGRQVHAHMVKARYRPPVYLATRLIILYVRCGALDDARNVLDGMPERNVVSWTAMISGYSQSGRHAEALELFIRMLRAGCKANEFTLATVLTSCPVHQ-SIQQVEQVHSLVVKTNFESHMFVGSSLLDMYGKSGNIQEARKVFDMLPERDTVSCTAIISGYAQLGLDDEALDLFRQLYSSGMQCNYVTFTTLLTSLSGLASLNYGKQVHGLILRKELPFFIVLQNSLIDMYSKCGKLLYSRRVFDNMPQRSAISWNAMLMGYGRHGIGQEVVQLFRTMTEE--VKPDSVTLLAVLSGCSHGGLVDEGLDIF-DLIVKEQNAVIHIGHYGCVIDLLGRSGQLQKALDLIEHMPFEPTPAIWGSLLGACRVHINVSVGEVVAQKLLDMEPGNAGNYVILSNIYAAAGMWKDVFRVRKLMLENTVTKEPAKSWIILDKVIHTFHSSERFHPRKKDINAKIKEVYVDVKAAGFVPDLSCVLHDVDDEQKERMLLGHSEKLAITFGLMNTPPGLTIQVMKNLRICVDCHNFAKFVSKVYGREISLRDKNRFHLLKDGACTCGDYW 595          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G   +F  Y   +  C+ RRA  EG++VHA M    Y P + L TRL+  Y  C  L+DA+ VLD MP R+VVSWT MIS YS+     EAL+LF++MLR+G  PNE+T ATVLTSC+G    +  G+Q+HSL++KT FESH+FVGSSLLDMYAK+  I EAR VF+ LPERDVVSCTAIISGYAQ GLDEEAL+LFRQL  EGM  N+VT+ +++TALSGLA+LD G+QVH  +LR+ELP +V LQNSLIDMYSKCG L YSRR+FD+M ER+V+SWNAML+GY +HG+G EV+ LFK + +E  V+PDSVT LAVLSGCSHGG+ D GL+ F  + + E        HYGC++DLLGR+GR+E+A   I+ M FE T +IWGSLLGACRVH+NV +GE V  +LL++EPENAGNYVILSN+YA+ G W+ V  VR+LM+EK V KEPG+SWI LD+++HTFH+S+R HP +                AG+VPDL CVL+DVD+EQKE++LLGHSEK+A+ FGL+ TP G+ +RV+KNLRICVDCHNFAK VSK+Y RE+SLRDKNRFH +  G C+CGDYW
Sbjct:   33 MALPGASARFHEYEAAITACIERRALWEGRQVHARMITARYRPAVFLGTRLVTMYVRCGALDDARNVLDRMPERSVVSWTTMISGYSQTERHVEALDLFIKMLRAGCIPNEYTLATVLTSCSGPQSIYQ-GKQVHSLLVKTNFESHMFVGSSLLDMYAKSENIQEARRVFDTLPERDVVSCTAIISGYAQKGLDEEALDLFRQLYSEGMQCNHVTFTTLVTALSGLASLDYGKQVHALILRKELPFFVALQNSLIDMYSKCGKLLYSRRVFDNMLERSVVSWNAMLMGYGRHGLGHEVISLFKDLHKE--VKPDSVTLLAVLSGCSHGGLVDEGLDIFDTVVK-EQSALLHTGHYGCIIDLLGRSGRLEKALNLIENMPFESTPSIWGSLLGACRVHANVHVGELVAQKLLEMEPENAGNYVILSNIYAAAGMWKDVFKVRKLMLEKTVTKEPGQSWIILDKVIHTFHSSERFHPSKKDINAKIKEIFVDIKAAGFVPDLSCVLHDVDDEQKERMLLGHSEKLAITFGLMNTPPGLTIRVMKNLRICVDCHNFAKFVSKVYEREISLRDKNRFHLLTHGNCTCGDYW 615          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G   +F  Y   +  C+ RRA  EG++VHA M    Y P + L TRL+  Y  C  L+DA+ VLD MP R+VVSWT MIS YS+     EAL+LF++MLR+G  PNE+T ATVLTSC+G    +  G+Q+HSL++KT FESH+FVGSSLLDMYAK+  I EAR VF+ LPERDVVSCTAIISGYAQ GLDEEAL+LFRQL  EGM  N+VT+ +++TALSGLA+LD G+QVH  +LR+ELP +V LQNSLIDMYSKCG L YSRR+FD+M ER+V+SWNAML+GY +HG+G EV+ LFK + +E  V+PDSVT LAVLSGCSHGG+ D GL+ F  + + E        HYGC++DLLGR+GR+E+A   I+ M FE T +IWGSLLGACRVH+NV +GE V  +LL++EPENAGNYVILSN+YA+ G W+ V  VR+LM+EK V KEPG+SWI LD+++HTFH+S+R HP +                AG+VPDL CVL+DVD+EQKE++LLGHSEK+A+ FGL+ TP G+ +RV+KNLRICVDCHNFAK VSK+Y RE+SLRDKNRFH +  G C+CGDYW
Sbjct:    1 MALPGASARFHEYEAAITACIERRALWEGRQVHARMITARYRPAVFLGTRLVTMYVRCGALDDARNVLDRMPERSVVSWTTMISGYSQTERHVEALDLFIKMLRAGCIPNEYTLATVLTSCSGPQSIYQ-GKQVHSLLVKTNFESHMFVGSSLLDMYAKSENIQEARRVFDTLPERDVVSCTAIISGYAQKGLDEEALDLFRQLYSEGMQCNHVTFTTLVTALSGLASLDYGKQVHALILRKELPFFVALQNSLIDMYSKCGKLLYSRRVFDNMLERSVVSWNAMLMGYGRHGLGHEVISLFKDLHKE--VKPDSVTLLAVLSGCSHGGLVDEGLDIFDTVVK-EQSALLHTGHYGCIIDLLGRSGRLEKALNLIENMPFESTPSIWGSLLGACRVHANVHVGELVAQKLLEMEPENAGNYVILSNIYAAAGMWKDVFKVRKLMLEKTVTKEPGQSWIILDKVIHTFHSSERFHPSKKDINAKIKEIFVDIKAAGFVPDLSCVLHDVDDEQKERMLLGHSEKLAITFGLMNTPPGLTIRVMKNLRICVDCHNFAKFVSKVYEREISLRDKNRFHLLTHGNCTCGDYW 583          

Query:   25 KFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +F  Y   + ECV RRA REG++VHA M    Y P ++L TRL++ Y  C  L DA+ VLD MP RNVVSWTAMIS YS+     +A  LF+ MLR+G                         +Q+H+  +KT FE H+FVGSSLLDMYAK+  I EAR VF+ LP RDVVS TAI+SGY QLGLDEEAL+LFR L  EGM  N VT+ ++L ALSGL+++D G+QVH  +LRRELP ++ LQNSLIDMYSKCG L YSRR+FDSMPER+V+SWNAML+GY +HG+  EVV+LF+ M +E  V+PDSVT LAVLSG SHGG+ D GL+ F  + + E  T    EHYGCV+DLLGR+G++++A   I+KM F+PT AIWGSLLGACRVH+NV +GEFV  +LL IEPENAGNYVILSN+YA+ G W+ V  VR+LM++K VIKEPGRSW+ LD+++HTFH+ +R HPR+                AG+VPDL CVL+DVD+EQKE++LLGHSEK+A+ FGL++TP  + ++V+KNLRICVDCHNFAK VSK+YGRE+SLRDKNRFH I  G C+CGDYW
Sbjct:   34 RFHDYDDAITECVERRALREGRQVHARMVAAGYRPALYLATRLVIMYARCGALEDARNVLDGMPERNVVSWTAMISGYSQNERPDQAWELFIMMLRAGIHQV---------------------KQVHAFAVKTNFELHMFVGSSLLDMYAKSENIQEARRVFDMLPARDVVSYTAILSGYTQLGLDEEALDLFRLLYNEGMQCNQVTFTALLNALSGLSSMDYGKQVHGLILRRELPFFMALQNSLIDMYSKCGKLLYSRRVFDSMPERSVVSWNAMLMGYGRHGLAHEVVQLFRSMCDE--VKPDSVTLLAVLSGYSHGGLVDEGLDMFDHIVK-EQSTLLNTEHYGCVIDLLGRSGQLQKALNLIEKMPFQPTRAIWGSLLGACRVHTNVHVGEFVAQKLLDIEPENAGNYVILSNIYAAAGMWKDVFRVRKLMLKKTVIKEPGRSWMILDKVIHTFHSCERFHPRKEDINAKIKEIYVAIKAAGFVPDLSCVLHDVDDEQKERMLLGHSEKLAITFGLMSTPSDLTIQVMKNLRICVDCHNFAKFVSKVYGREISLRDKNRFHLITEGACTCGDYW 588          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVR 1581
            MA+ G   +F  Y   +  C+ RRA  EG++VHA M    Y P + L TRL+  Y  C  L+DA+ VLD MP R+VVSWT MIS YS+     EAL+LF++MLR+G  PNE+T ATVLTSC+G    +  G+Q+HSL++KT FESH+FVGSSLLDMYAK+  I EAR VF+ LPERDVVSCTAIISGYAQ GLDEEAL+LFRQL  EGM  N+VT+ +++TALSGLA+LD G+QVH  +LR+ELP +V LQNSLIDMYSKCG L YSRR+FD+M ER+V+SWNAML+GY +HG+G EV+ LFK + +E  V+PDSVT LAVLSGCSHGG+ D GL+ F  + + E        HYGC++DLLGR+GR+E+A   I+ M FE T +IWGSLLGACRVH+NV +GE V  +LL++EPENAGNYVILSN+YA+ G W+ V  VR+LM+EK V KEPG+SWI LD+++HTFH+S+R HP +                AG+VPDL CVL+DVD+EQKE++LLGHSEK+A+ FGL+ TP G+ +R
Sbjct:    1 MALPGASARFHEYEAAITACIERRALWEGRQVHARMITARYRPAVFLGTRLVTMYVRCGALDDARNVLDRMPERSVVSWTTMISGYSQTERHVEALDLFIKMLRAGCIPNEYTLATVLTSCSGPQSIYQ-GKQVHSLLVKTNFESHMFVGSSLLDMYAKSENIQEARRVFDTLPERDVVSCTAIISGYAQKGLDEEALDLFRQLYSEGMQCNHVTFTTLVTALSGLASLDYGKQVHALILRKELPFFVALQNSLIDMYSKCGKLLYSRRVFDNMLERSVVSWNAMLMGYGRHGLGHEVISLFKDLHKE--VKPDSVTLLAVLSGCSHGGLVDEGLDIFDTVVK-EQSALLHTGHYGCIIDLLGRSGRLEKALNLIENMPFESTPSIWGSLLGACRVHANVHVGELVAQKLLEMEPENAGNYVILSNIYAAAGMWKDVFKVRKLMLEKTVTKEPGQSWIILDKVIHTFHSSERFHPSKKDINAKIKEIFVDIKAAGFVPDLSCVLHDVDDEQKERMLLGHSEKLAITFGLMNTPPGLTIR 535          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G EM F GY  LLN C+++RA R+GQRVHAHM KT YLP  +LRTRL++FY  C+CL DA++VLDEMP +NVVSWTAMIS YS+ G +SEAL +F +M+RS  +PNEFTFATVLTSC   + G  LG+QIH LI+K  ++SHIFVGSSLLDMYAKAG+I EAR +FECLPERDVVSCTAII+GYAQLGLDEEALE+F +L  EGM+ NYVTYAS+LTALSGLA LD G+Q H HVLRRELP Y VLQNSLIDMYSKCGNLSY+RR+FD+MPERT ISWNAMLVGYSKHG+G+EV++LF+LM++E +V+PD+VT LAVLSGCSHG MED GL  F  M  GE GT+P  EHYGC+VD+LGRAGR++EAFEFIK+M  +PTA + GSLLGACRVH +V+IGE VG RL++IEPENAGNYVILSNLYAS GRW  V NVR +M++KAV KEPGRSWI+ +Q LH FHA+DR+HPRR   +            AGYVPDL CVLYDVDEEQKEK+LLGHSEK+AL FGLIAT EG+P+RV KNLRICVDCHNFAK+ SK++ REVSLRDKNRFH IV G CSCGDYW
Sbjct:   43 MAMLGPEMGFHGYDALLNACLDKRALRDGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALTVFAEMMRSDGKPNEFTFATVLTSCIRAS-GLGLGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIKEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFHRLHSEGMSPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYARRLFDNMPERTAISWNAMLVGYSKHGLGREVLELFRLMRDEKRVKPDAVTLLAVLSGCSHGRMEDTGLNIFDGMVAGEYGTKPGTEHYGCIVDMLGRAGRIDEAFEFIKRMPSKPTAGVLGSLLGACRVHLSVDIGESVGRRLIEIEPENAGNYVILSNLYASAGRWADVNNVRAMMMQKAVTKEPGRSWIQHEQTLHYFHANDRTHPRREEVLAKMKEISIKMKQAGYVPDLSCVLYDVDEEQKEKMLLGHSEKLALTFGLIATGEGIPIRVFKNLRICVDCHNFAKIFSKVFEREVSLRDKNRFHQIVDGICSCGDYW 628          

Query:  508 FECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLF-KLMKEENKVRPDSVTFLAVLSGC----------------------SHGGMEDRGLEYFYEMAEGENGTE-----PELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFE---PTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIE-PENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVI 1350
            F   P   V+     IS     G  +EAL     L   G    +  Y ++L A     AL  G++VH H+++        L+  L+  Y KC  L  +R++ D MPE+ V+SW AM+  YS+ G   E + +F ++M+ + K  P+  TF  VL+ C                      SH  +    L+ + +  + +   E     PE +   C   + G A  G  EEA E   ++  E   P    + SLL A    + ++ G+     +L+ E P  A     L ++Y+  G     R + + M E+  I
Sbjct:   12 FSSSPTNYVLQTILPISQLCSNGRLQEALLEMAML---GPEMGFHGYDALLNACLDKRALRDGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALTVFAEMMRSDGK--PNEFTFATVLTSCIRASGLGLGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIKEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFHRLHSEGMSPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYARRLFDNMPERTAI 321          

Query:   46 LLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDA-------------------------------QRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRR--ELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +L  C   +AF+EGQ++H H+ K      +++ T LI  Y     L DA                               Q++ DE+PV++VVSW AMIS Y++ G   EAL LF  M+++   P+E T  TV+++CA      +LGRQ+H  I    F S++ + ++L+D+Y+K G +  A G+FE LP +DV+S   +I GY  + L +EAL LF+++ R G T N VT  S+L A + L A+D+GR +H ++ +R   + +   L+ SLIDMY+KCG++  + ++F+S+  +++ SWNAM+ G++ HG       LF  M++   ++PD +TF+ +LS CSH GM D G   F  M +    T P+LEHYGC++DLLG +G  +EA E I  M  EP   IW SLL AC++H NVE+GE     L++IEPEN G+YV+LSN+YAS GRW  V   R L+ +K + K PG S IE+D ++H F   D+ HPR                 AG+VPD   VL +++EE KE  L  HSEK+A+AFGLI+T  G  + ++KNLR+C +CH   KL+SKIY RE+  RD+ RFHH   G CSC DYW
Sbjct:  140 VLKSCAKSKAFKEGQQIHGHVLKLGCDLDLYVHTSLISMYVQNGRLEDAHKVFDKSPHRDVVSYTALIKGYASRGYIENAQKLFDEIPVKDVVSWNAMISGYAETGNYKEALELFKDMMKTNVRPDESTMVTVVSACAQSG-SIELGRQVHLWIDDHGFGSNLKIVNALIDLYSKCGELETACGLFERLPYKDVISWNTLIGGYTHMNLYKEALLLFQEMLRSGETPNDVTMLSILPACAHLGAIDIGRWIHVYIDKRLKGVTNASSLRTSLIDMYAKCGDIEAAHQVFNSILHKSLSSWNAMIFGFAMHGRADASFDLFSRMRKIG-IQPDDITFVGLLSACSHSGMLDLGRHIFRTMTQDYKMT-PKLEHYGCMIDLLGHSGLFKEAEEMINMMEMEPDGVIWCSLLKACKMHGNVELGESFAENLIKIEPENPGSYVLLSNIYASAGRWNEVAKTRALLNDKGMKKVPGCSSIEIDSVVHEFIIGDKFHPRNREIYGMLEEMEVLLEKAGFVPDTSEVLQEMEEEWKEGALRHHSEKLAIAFGLISTKPGTKLTIVKNLRVCRNCHEATKLISKIYKREIIARDRTRFHHFRDGVCSCNDYW 741          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFY---NNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAI-------------------------------ISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVH--SNVEIGEFVGFRLLQIEPEN 1251
            +LL+ C   ++ R    +HA M K       +  ++LI F     + E L  A  V   +   N++ W  M   ++       AL L++ M+  G  PN +TF  VL SCA     F  G+QIH  ++K   +  ++V +SL+ MY + GR+ +A  VF+  P RDVVS TA+                               ISGYA+ G  +EALELF+ + +  +  +  T  +V++A +   +++LGRQVH  +      S + + N+LID+YSKCG L  +  +F+ +P + VISWN ++ GY+   + KE + LF+ M    +  P+ VT L++L  C+H G  D G      + +   G          ++D+  + G +E A +    +    + + W +++    +H  ++     F   R + I+P++
Sbjct:   38 SLLHNCKTLQSLRI---IHAQMIKIGLHNTNYALSKLIEFCILSPHFEGLPYAISVFKTIQEPNLLIWNTMFRGHALSSDPVSALKLYVCMISLGLLPNSYTFPFVLKSCAKSK-AFKEGQQIHGHVLKLGCDLDLYVHTSLISMYVQNGRLEDAHKVFDKSPHRDVVSYTALIKGYASRGYIENAQKLFDEIPVKDVVSWNAMISGYAETGNYKEALELFKDMMKTNVRPDESTMVTVVSACAQSGSIELGRQVHLWIDDHGFGSNLKIVNALIDLYSKCGELETACGLFERLPYKDVISWNTLIGGYTHMNLYKEALLLFQEMLRSGET-PNDVTMLSILPACAHLGAIDIGRWIHVYIDKRLKGVTNASSLRTSLIDMYAKCGDIEAAHQVFNSI-LHKSLSSWNAMIFGFAMHGRADASFDLFSRMRKIGIQPDD 470          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y TLL +C   +   +G+ VHAH+ ++ +   + +   L+  Y  C  L +A++V ++MP R+ V+WT +IS YS+     +AL  F QMLR G  PNEFT ++V+ + A    G   G Q+H   +K  F+S++ VGS+LLD+Y + G + +A+ VF+ L  R+ VS  A+I+G+A+    E+ALELF+ + R+G   ++ +YAS+  A S    L+ G+ VH ++++          N+L+DMY+K G++  +R+IFD + +R V+SWN++L  Y++HG GKE V  F+ M+    +RP+ ++FL+VL+ CSH G+ D G  Y YE+ + ++G  PE  HY  VVDLLGRAG +  A  FI++M  EPTAAIW +LL ACR+H N E+G +    + +++P++ G +VIL N+YAS GRW     VR+ M E  V KEP  SW+E++  +H F A+D  HP+R                 GYVPD   V+  VD++++E  L  HSEK+ALAF L+ TP G  + + KN+R+C DCH   KL SK+ GRE+ +RD NRFHH   G CSC DYW
Sbjct:   63 YNTLLKKCTVFKLLIQGRIVHAHILQSIFRHDIVMGNTLLNMYAKCGSLEEARKVFEKMPQRDFVTWTTLISGYSQHDRPCDALLFFNQMLRFGYSPNEFTLSSVIKAAAAERRGC-CGHQLHGFCVKCGFDSNVHVGSALLDLYTRYGLMDDAQLVFDALESRNDVSWNALIAGHARRSGTEKALELFQGMLRDGFRPSHFSYASLFGACSSTGFLEQGKWVHAYMIKSGEKLVAFAGNTLLDMYAKSGSIHDARKIFDRLAKRDVVSWNSLLTAYAQHGFGKEAVWWFEEMRRVG-IRPNEISFLSVLTACSHSGLLDEGWHY-YELMK-KDGIVPEAWHYVTVVDLLGRAGDLNRALRFIEEMPIEPTAAIWKALLNACRMHKNTELGAYAAEHVFELDPDDPGPHVILYNIYASGGRWNDAARVRKKMKESGVKKEPACSWVEIENAIHMFVANDERHPQREEIARKWEEVLAKIKELGYVPDTSHVIVHVDQQEREVNLQYHSEKIALAFALLNTPPGSTIHIKKNIRVCGDCHTAIKLASKVVGREIIVRDTNRFHHFKDGNCSCKDYW 633          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR-------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y  L+  C++ RA  EG  +  H+    + P M L   LI  Y     LNDA ++ D+MP RNV+SWT MISAYSK     +AL L + MLR    PN +T+++VL SC G +   D+ R +H  IIK   ES +FV S+L+D++AK G   +A  VF+ +   D +   +II G+AQ    + ALELF++++R G  +   T  SVL A +GLA L+LG Q H H+++ +    ++L N+L+DMY KCG+L  + R+F+ M ER VI+W+ M+ G +++G  +E +KLF+ MK     +P+ +T + VL  CSH G+ + G  YF  M +   G +P  EHYGC++DLLG+AG++++A + + +M  EP A  W +LLGACRV  N+ + E+   +++ ++PE+AG Y +LSN+YA+  +W+ V  +R  M ++ + KEPG SWIE+++ +H F   D SHP+             R  G+ GYVP+   VL D++ EQ E  L  HSEK+ALAFGL+  P    +R+ KNLRIC DCH F KL SK+  R + +RD  R+HH   G CSCGDYW
Sbjct:   64 YSELIKCCISNRAVHEGNLICRHLYFNGHRPMMFLVNVLINMYVKFNLLNDAHQLFDQMPQRNVISWTTMISAYSKCKIHQKALELLVLMLRDNVRPNVYTYSSVLRSCNGMS---DV-RMLHCGIIKEGLESDVFVRSALIDVFAKLGEPEDALSVFDEMVTGDAIVWNSIIGGFAQNSRSDVALELFKRMKRAGFIAEQATLTSVLRACTGLALLELGMQAHVHIVKYDQD--LILNNALVDMYCKCGSLEDALRVFNQMKERDVITWSTMISGLAQNGYSQEALKLFERMKSSG-TKPNYITIVGVLFACSHAGLLEDGWYYFRSMKK-LYGIDPVREHYGCMIDLLGKAGKLDDAVKLLNEMECEPDAVTWRTLLGACRVQRNMVLAEYAAKKVIALDPEDAGTYTLLSNIYANSQKWDSVEEIRTRMRDRGIKKEPGCSWIEVNKQIHAFIIGDNSHPQIVEVSKKLNQLIHRLTGI-GYVPETNFVLQDLEGEQMEDSLRHHSEKLALAFGLMTLPIEKVIRIRKNLRICGDCHVFCKLASKLEIRSIVIRDPIRYHHFQDGKCSCGDYW 630          

Query:  544 TAIISGYAQLGLDEE---ALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEI 1206
            T ++S + +L    +   A++    LQ  G+ ++  TY+ ++       A+  G  +  H+        + L N LI+MY K   L+ + ++FD MP+R VISW  M+  YSK  + ++ ++L  LM  +N VRP+  T+ +VL  C+  GM D  + +   + E   G E ++     ++D+  + G  E+A     +M     A +W S++G    +S  ++
Sbjct:   27 TLLLSEFTRLCYQRDLPRAMKAMDSLQSHGLWADSATYSELIKCCISNRAVHEGNLICRHLYFNGHRPMMFLVNVLINMYVKFNLLNDAHQLFDQMPQRNVISWTTMISAYSKCKIHQKALELLVLMLRDN-VRPNVYTYSSVLRSCN--GMSDVRMLHCGIIKE---GLESDVFVRSALIDVFAKLGEPEDALSVFDEM-VTGDAIVWNSIIGGFAQNSRSDV 243          

Query:   85 GQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTF------ATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGR--IYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQL-QREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            G++ H       Y   + + + LIV Y+ C  L DA++V DE+P RN+VSWT+MI  Y   G A +A++LF  +L    + ++  F       +V+++C+       L   IHS +IK  F+  + VG++LLD YAK G   +  AR +F+ + ++D VS  +I+S YAQ G+  EA E+FR+L + + +T N +T ++VL A+S   AL +G+ +H+ V+R  L   V++  S+IDMY KCG +  +R+ FD M  + V SW AM+ GY  HG   + ++LF  M +   VRP+ +TF++VL+ CSH G+   G  +F  M +G  G EP LEHYGC+VDLLGRAG +++A++ I++M+ +P + IW SLL ACR+H NVE+ E    RL +++  N G Y++LS++YA  GRW+ V  VR +M  + ++K PG S +EL+  +H F   D  HP+R +              AGYV +   V +DVDEE+KE  L  HSEK+A+AFG++ T  G  V V+KNLR+C DCHN  KL+SKI  RE  +RD  RFHH   G CSCGDYW
Sbjct:   95 GKQTHQQAFVFGYQSDIFVSSALIVMYSTCGKLEDARKVFDEIPKRNIVSWTSMIRGYDLNGNALDAVSLFKDLLVDENDDDDAMFLDSMGLVSVISACSRVP-AKGLTESIHSFVIKRGFDRGVSVGNTLLDAYAKGGEGGVAVARKIFDQIVDKDRVSYNSIMSVYAQSGMSNEAFEVFRRLVKNKVVTFNAITLSTVLLAVSHSGALRIGKCIHDQVIRMGLEDDVIVGTSIIDMYCKCGRVETARKAFDRMKNKNVRSWTAMIAGYGMHGHAAKALELFPAMIDSG-VRPNYITFVSVLAACSHAGLHVEGWRWFNAM-KGRFGVEPGLEHYGCMVDLLGRAGFLQKAYDLIQRMKMKPDSIIWSSLLAACRIHKNVELAEISVARLFELDSSNCGYYMLLSHIYADAGRWKDVERVRMIMKNRGLVKPPGFSLLELNGEVHVFLIGDEEHPQREKIYEFLAELNRKLLEAGYVSNTSSVCHDVDEEEKEMTLRVHSEKLAIAFGIMNTVPGSTVNVVKNLRVCSDCHNVIKLISKIVDREFVVRDAKRFHHFKDGGCSCGDYW 659          

Query:  223 NVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDL--GRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQL------QREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKC--GNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSN 1197
            +V SW ++I+  ++ G ++EAL  F  M +    P   +F   + +C+     FD+  G+Q H       ++S IFV S+L+ MY+  G++ +AR VF+ +P+R++VS T++I GY   G   +A+ LF+ L        + M  + +   SV++A S + A  L   +H+ V++R     V + N+L+D Y+K   G ++ +R+IFD + ++  +S+N+++  Y++ GM  E  ++F+ + +   V  +++T   VL   SH G    G     ++     G E ++     ++D+  + GRVE A +   +M+       W +++    +H +
Sbjct:   40 DVFSWNSVIADLARSGDSAEALLAFSSMRKLSLYPTRSSFPCAIKACSS---LFDIFSGKQTHQQAFVFGYQSDIFVSSALIVMYSTCGKLEDARKVFDEIPKRNIVSWTSMIRGYDLNGNALDAVSLFKDLLVDENDDDDAMFLDSMGLVSVISACSRVPAKGLTESIHSFVIKRGFDRGVSVGNTLLDAYAKGGEGGVAVARKIFDQIVDKDRVSYNSIMSVYAQSGMSNEAFEVFRRLVKNKVVTFNAITLSTVLLAVSHSGALRIGKCIHDQVI--RMGLEDDVIVGTSIIDMYCKCGRVETARKAFDRMK-NKNVRSWTAMIAGYGMHGH 368          

Query:  529 DVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFK-LMKEEN----KVRPDSVTFLAVLSGCS-----------HGGMEDRGLEYFYEMAE---------GENG-----------TEPELEHYGCVVDLLGRAGRVEEAFE----FIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPEN---AGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSW 1371
            DV S  ++I+  A+ G   EAL  F  +++  +     ++   + A S L  +  G+Q H         S + + ++LI MYS CG L  +R++FD +P+R ++SW +M+ GY  +G   + V LFK L+ +EN     +  DS+  ++V+S CS           H  +  RG +    +           GE G            + +   Y  ++ +  ++G   EAFE     +K       A    ++L A      + IG+ +  +++++  E+    G  +I  ++Y   GR E  R   + M  K V     RSW
Sbjct:   40 DVFSWNSVIADLARSGDSAEALLAFSSMRKLSLYPTRSSFPCAIKACSSLFDIFSGKQTHQQAFVFGYQSDIFVSSALIVMYSTCGKLEDARKVFDEIPKRNIVSWTSMIRGYDLNGNALDAVSLFKDLLVDENDDDDAMFLDSMGLVSVISACSRVPAKGLTESIHSFVIKRGFDRGVSVGNTLLDAYAKGGEGGVAVARKIFDQIVDKDRVSYNSIMSVYAQSGMSNEAFEVFRRLVKNKVVTFNAITLSTVLLAVSHSGALRIGKCIHDQVIRMGLEDDVIVGTSII--DMYCKCGRVETARKAFDRMKNKNV-----RSW 356          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEA 498
            T+L    +  A R G+ +H  + +      + + T +I  Y  C  +  A++  D M  +NV SWTAMI+ Y   G A++AL LF  M+ SG  PN  TF +VL +C+      +  R  +++  +   E  +     ++D+  +AG + +A
Sbjct:  292 TVLLAVSHSGALRIGKCIHDQVIRMGLEDDVIVGTSIIDMYCKCGRVETARKAFDRMKNKNVRSWTAMIAGYGMHGHAAKALELFPAMIDSGVRPNYITFVSVLAACSHAGLHVEGWRWFNAMKGRFGVEPGLEHYGCMVDLLGRAGFLQKA 443          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFD---LGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTS--NYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGVA------------GYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y  L+  C +R +  +  RVH H+          L T+LI  Y++   ++ A++V D+   R +  W A+  A +  G   E L L+ +M R G E + FT+  VL +C       +    G++IH+ + +  + SH+++ ++L+DMYA+ G +  A  VF  +P R+VVS +A+I+ YA+ G   EAL  FR++ RE   S  N VT  SVL A + LAAL+ G+ +H ++LRR L S + + ++L+ MY +CG L   +R+FD M +R V+SWN+++  Y  HG GK+ +++F+ M   N   P  VTF++VL  CSH G+ + G   F  M   ++G +P++EHY C+VDLLGRA R++EA + ++ MR EP   +WGSLLG+CR+H NVE+ E    RL  +EP+NAGNYV+L+++YA    W+ V+ V++L+  + + K PGR W+E+ + +++F + D  +P   +  A            GY+P    VLY+++ E+KE+++LGHSEK+ALAFGLI T +G P+R+ KNLR+C DCH F K +SK   +E+ +RD NRFH    G CSCGDYW
Sbjct:   80 YELLILCCGHRSSLSDALRVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTRKRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIGVESDRFTYTYVLKACVASECTVNHLMKGKEIHAHLTRRGYSSHVYIMTTLVDMYARFGCVDYASYVFGGMPVRNVVSWSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSVLQACASLAALEQGKLIHGYILRRGLDSILPVISALVTMYGRCGKLEVGQRVFDRMHDRDVVSWNSLISSYGVHGYGKKAIQIFEEMLA-NGASPTPVTFVSVLGACSHEGLVEEGKRLFETMWR-DHGIKPQIEHYACMVDLLGRANRLDEAAKMVQDMRTEPGPKVWGSLLGSCRIHGNVELAERASRRLFALEPKNAGNYVLLADIYAEAQMWDEVKRVKKLLEHRGLQKLPGRCWMEVRRKMYSFVSVDEFNPLMEQIHAFLVKLAEDMKEKGYIPQTKGVLYELETEEKERIVLGHSEKLALAFGLINTSKGEPIRITKNLRLCEDCHLFTKFISKFMEKEILVRDVNRFHRFKNGVCSCGDYW 657          

Query:  595 ELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGC 975
            +  R L +E   S   TY  ++      ++L    +VH H+L         L   LI MYS  G++ Y+R++FD   +RT+  WNA+    +  G G+EV+ L+  M     V  D  T+  VL  C
Sbjct:   64 QAIRVLSQESSPSQQ-TYELLILCCGHRSSLSDALRVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTRKRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIG-VESDRFTYTYVLKAC 188          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMP-VRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGL-AALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVG-GTCSCGDYW 1725
            M +  + +    + +++  C N +  R  +++H  + K  +L   ++RT L+V Y+ C  + DA R+  E+  V NVVSWTAMIS + +     EA++LF +M R G  PNEFT++ +LT     A       ++H+ ++KT +E    VG++LLD Y K G++ EA  VF  + ++D+V+ +A+++GYAQ G  E A+++F +L + G+  N  T++S+L   +   A++  G+Q H   ++  L S + + ++L+ MY+K GN+  +  +F    E+ ++SWN+M+ GY++HG   + + +FK MK+  KV+ D VTF+ V + C+H G+ + G +YF  M   +    P  EH  C+VDL  RAG++E+A + I+ M     + IW ++L ACRVH   E+G     +++ ++PE++  YV+LSN+YA  G W+    VR+LM E+ V KEPG SWIE+    ++F A DRSHP + +               GY PD   VL D+D+E KE VL  HSE++A+AFGLIATP+G P+ +IKNLR+C DCH   KL++KI  RE+ +RD NRFHH    G CSCGD+W
Sbjct:  286 MRLNYVRLSESSFASVIKLCANLKELRFTEQLHCSVVKYGFLFDQNIRTALMVAYSKCTAMLDALRLFKEIGCVGNVVSWTAMISGFLQNDGKEEAVDLFSEMKRKGVRPNEFTYSVILT-----ALPVISPSEVHAQVVKTNYERSSTVGTALLDAYVKLGKVEEAAKVFSGIDDKDIVAWSAMLAGYAQTGETEAAIKMFGELTKGGIKPNEFTFSSILNVCAATNASMGQGKQFHGFAIKSRLDSSLCVSSALLTMYAKKGNIESAEEVFKRQREKDLVSWNSMISGYAQHGQAMKALDVFKEMKKR-KVKMDGVTFIGVFAACTHAGLVEEGEKYFDIMVR-DCKIAPTKEHNSCMVDLYSRAGQLEKAMKVIENMPNPAGSTIWRTILAACRVHKKTELGRLAAEKIIAMKPEDSAAYVLLSNMYAESGDWQERAKVRKLMNERNVKKEPGYSWIEVKNKTYSFLAGDRSHPLKDQIYMKLEDLSTRLKDLGYEPDTSYVLQDIDDEHKEAVLAQHSERLAIAFGLIATPKGSPLLIIKNLRVCGDCHLVIKLIAKIEEREIVVRDSNRFHHFSSDGVCSCGDFW 868          

Query:   85 GQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMP-ERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLS 969
            G+++H    K  +L  + + T L+  Y       D ++V DEM  RNVV+WT +IS Y++     E L LF++M   GT+PN FTFA  L   A    G   G Q+H++++K   +  I V +SL+++Y K G + +AR +F+    + VV+  ++ISGYA  GLD EAL +F  ++   +  +  ++ASV+   + L  L    Q+H  V++        ++ +L+  YSKC  +  + R+F  +     V+SW AM+ G+ ++   +E V LF  MK +  VRP+  T+  +L+
Sbjct:  112 GRQLHCQCIKFGFLDDVSVGTSLVDTYMKGSNFKDGRKVFDEMKERNVVTWTTLISGYARNSMNDEVLTLFMRMQNEGTQPNSFTFAAALGVLAEEGVG-GRGLQVHTVVVKNGLDKTIPVSNSLINLYLKCGNVRKARILFDKTEVKSVVTWNSMISGYAANGLDLEALGMFYSMRLNYVRLSESSFASVIKLCANLKELRFTEQLHCSVVKYGFLFDQNIRTALMVAYSKCTAMLDALRLFKEIGCVGNVVSWTAMISGFLQNDGKEEAVDLFSEMKRKG-VRPNEFTYSVILT 405          

Query:  181 LNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSH 981
            L +A  + D+ P R+  S+ +++  +S+ G   EA  LFL + R G E +   F++VL   A        GRQ+H   IK  F   + VG+SL+D Y K     + R VF+ + ER+VV+ T +ISGYA+  +++E L LF ++Q EG   N  T+A+ L  L+       G QVH  V++  L   + + NSLI++Y KCGN+  +R +FD    ++V++WN+M+ GY+ +G+  E + +F  M+  N VR    +F +V+  C++
Sbjct:   43 LYNAHNLFDKSPGRDRESYISLLFGFSRDGRTQEAKRLFLNIHRLGMEMDCSIFSSVLKVSATLCDEL-FGRQLHCQCIKFGFLDDVSVGTSLVDTYMKGSNFKDGRKVFDEMKERNVVTWTTLISGYARNSMNDEVLTLFMRMQNEGTQPNSFTFAAALGVLAEEGVGGRGLQVHTVVVKNGLDKTIPVSNSLINLYLKCGNVRKARILFDKTEVKSVVTWNSMISGYAANGLDLEALGMFYSMR-LNYVRLSESSFASVIKLCAN 307          

Query:  478 AGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHS-NVE-IGEFVGFRLLQIEPENAGNYVILS-NLYASV 1293
            + R+Y A  +F+  P RD  S  +++ G+++ G  +EA  LF  + R GM  +   ++SVL   + L     GRQ+H   ++      V +  SL+D Y K  N    R++FD M ER V++W  ++ GY+++ M  EV+ LF  M+ E   +P+S TF A L   +  G+  RGL+    +   +NG +  +     +++L  + G V +A     K   + +   W S++     +  ++E +G F   RL         NYV LS + +ASV
Sbjct:   40 SSRLYNAHNLFDKSPGRDRESYISLLFGFSRDGRTQEAKRLFLNIHRLGMEMDCSIFSSVLKVSATLCDELFGRQLHCQCIKFGFLDDVSVGTSLVDTYMKGSNFKDGRKVFDEMKERNVVTWTTLISGYARNSMNDEVLTLFMRMQNEG-TQPNSFTFAAALGVLAEEGVGGRGLQVHTVVV--KNGLDKTIPVSNSLINLYLKCGNVRKARILFDKTEVK-SVVTWNSMISGYAANGLDLEALGMFYSMRL---------NYVRLSESSFASV 301          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPP-MHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRS-GTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQ-----------REGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKM-RFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M ++G+E       ++L  C +    R G+ +HA+  K   L     + + L+  Y NC+ +   +RV D M  R +  W AMI+ YS+     EAL LF+ M  S G   N  T A V+ +C      F     IH  ++K   +   FV ++L+DMY++ G+I  A  +F  + +RD+V+   +I+GY      E+AL L  ++Q           R  +  N +T  ++L + + L+AL  G+++H + ++  L + V + ++L+DMY+KCG L  SR++FD +P++ VI+WN +++ Y  HG G+E + L ++M  +  V+P+ VTF++V + CSH GM D GL  FY M + + G EP  +HY CVVDLLGRAGR++EA++ +  M R    A  W SLLGA R+H+N+EIGE     L+Q+EP  A +YV+L+N+Y+S G W+    VR  M E+ V KEPG SWIE    +H F A D SHP+  +               GYVPD  CVL++V+E++KE +L GHSEK+A+AFG++ T  G  +RV KNLR+C DCH   K +SKI  RE+ LRD  RFH    GTCSCGDYW
Sbjct:  293 MVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSG-AFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQG-VKPNEVTFISVFAACSHSGMVDEGLRIFYVM-KPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYLETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCY-LPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAW--GFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRR-ELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEG---ENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL 1173
            M V G++     +  LL    + +    G+++HAH+ K  Y +  + +   L+  Y  C       +V D +  RN VSW ++IS+         AL  F  ML    EP+ FT  +V+T+C+      G  +G+Q+H+  ++ K E + F+ ++L+ MY K G++  ++ +      RD+V+   ++S   Q     EALE  R++  EG+  +  T +SVL A S L  L  G+++H + L+   L     + ++L+DMY  C  +   RR+FD M +R +  WNAM+ GYS++   KE + LF  M+E   +  +S T   V+  C   G   R      E   G   + G + +      ++D+  R G+++ A     KM  +     W +++
Sbjct:   88 MIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLR-KGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSR-----KEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKME-DRDLVTWNTMI 478          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLII-KTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREG-MTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHP------------RRHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +LL+ C     F  G  +H++  K      + +  +LI  Y     L D Q+V D M VR+++SW ++I AY        A++LF +M  S  +P+  T  + L S           R +    + K  F   I +G++++ MYAK G +  AR VF  LP  DV+S   IISGYAQ G   EA+E++  ++ EG + +N  T+ SVL A S   AL  G ++H  +L+  L   V +  SL DMY KCG L  +  +F  +P    + WN ++  +  HG G++ V LFK M +E  V+PD +TF+ +LS CSH G+ D G ++ +EM + + G  P L+HYGC+VD+ GRAG++E A +FIK M  +P A+IWG+LL ACRVH NV++G+     L ++EPE+ G +V+LSN+YAS G+WEGV  +R +   K + K PG S +E+D  +  F+  +++HP            +    + GYVPD   VL DV++++KE +L+ HSE++A+AF LIATP    +R+ KNLR+C DCH+  K +SKI  RE+ +RD NRFHH   G CSCGDYW
Sbjct:  252 SLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSRIQPDCLTLIS-LASILSQLGDIRACRSVQGFTLRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLLKNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEG-VKPDHITFVTLLSACSHSGLVDEG-QWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVDLGKIASEHLFEVEPEHVGYHVLLSNMYASAGKWEGVDEIRSIAHGKGLRKTPGWSSMEVDNKVEVFYTGNQTHPMYEEMYRELTALQAKLKMIGYVPDHRFVLQDVEDDEKEHILMSHSERLAIAFALIATPAKTTIRIFKNLRVCGDCHSVTKFISKITEREIIVRDSNRFHHFKNGVCSCGDYW 823          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRE-LPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVE 1203
            M   GL   +  + ++L  C   R   +G ++H    K  ++  +++   LI  Y+  + + +A+ + DEMPVR++ SW AMIS Y + G A EAL L      +G    +      L S    A  F+ G  IHS  IK   ES +FV + L+D+YA+ GR+ + + VF+ +  RD++S  +II  Y        A+ LF++++   +  + +T  S+ + LS L  +   R V    LR+      + + N+++ MY+K G +  +R +F+ +P   VISWN ++ GY+++G   E ++++ +M+EE ++  +  T+++VL  CS  G   +G++    +   +NG   ++     + D+ G+ GR+E+A     ++     +  W +L+     H + E
Sbjct:  144 MLSSGLTPDYRTFPSVLKAC---RTVIDGNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTL-----SNGLRAMDSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSRIQPDCLTLISLASILSQLGDIRACRSVQGFTLRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLL--KNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIP-RVNSVPWNTLIACHGFHGHGE 534          

Query:   25 KFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLF-LQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGG 987
            + +  +TL   C N    +  + +HA +  +  +  + +  +L+  Y     +  A+   D +  R+V +W  MIS Y + G +SE +  F L ML SG  P+  TF +VL +C         G +IH L +K  F   ++V +SL+ +Y++   +  AR +F+ +P RD+ S  A+ISGY Q G  +EAL L   L+      + VT  S+L+A +     + G  +H++ ++  L S + + N LID+Y++ G L   +++FD M  R +ISWN+++  Y  +      + LF+ M+  ++++PD +T +++ S  S  G
Sbjct:   53 EIDDVHTLFRYCTN---LQSAKCLHARLVVSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKACR----TVIDGNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTLSNGLR----AMDSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMR-LSRIQPDCLTLISLASILSQLG 362          

Query:  400 IHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQ-LQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRP-DSVTFLAVLSGCSHGGMEDRGLE-YFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNV--EIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEK 1341
            +H+ ++ +K   ++ + + L+++Y   G +  AR  F+ +  RDV +   +ISGY + G   E +  F   +   G+T +Y T+ SVL A      +D G ++H   L+      V +  SLI +YS+   +  +R +FD MP R + SWNAM+ GY + G  KE + L       N +R  DSVT +++LS C+  G  +RG+  + Y +   ++G E EL     ++DL    GR+ +  +   +M      + W S++ A  ++      I  F   RL +I+P+     + L+++ + +G     R+V+   + K
Sbjct:   73 LHARLVVSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKACR--TVID-GNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTL------SNGLRAMDSVTVVSLLSACTEAGDFNRGVTIHSYSI---KHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLIS-WNSIIKAYELNEQPLRAISLFQEMRLSRIQPD-CLTLISLASILSQLGDIRACRSVQGFTLRK 377          

Query:  181 LNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            ++  +RV + MP ++VVS+  +I+ Y++ G   +AL +  +M  +  +P+ FT ++VL   +        G++IH  +I+   +S +++GSSL+DMYAK+ RI ++  VF  L  RD +S  ++++GY Q G   EAL LFRQ+    +    V ++SV+ A + LA L LG+Q+H +VLR    S + + ++L+DMYSKCGN+  +R+IFD M     +SW A+++G++ HG G E V LF+ MK +  V+P+ V F+AVL+ CSH G+ D    YF  M +   G   ELEHY  V DLLGRAG++EEA+ FI KM  EPT ++W +LL +C VH N+E+ E V  ++  ++ EN G YV++ N+YAS GRW+ +  +R  M +K + K+P  SWIE+    H F + DRSHP   +               GYV D   VL+DVDEE K ++L GHSE++A+AFG+I T  G  +RV KN+RIC DCH   K +SKI  RE+ +RD +RFHH   G CSCGDYW
Sbjct:  192 IDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTDLKPDSFTLSSVLPIFSEYV-DVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQG-VKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTK-VYGLNQELEHYAAVADLLGRAGKLEEAYNFISKMCVEPTGSVWSTLLSSCSVHKNLELAEKVAEKIFTVDSENMGAYVLMCNMYASNGRWKEMAKLRLRMRKKGLRKKPACSWIEMKNKTHGFVSGDRSHPSMDKINEFLKAVMEQMEKEGYVADTSGVLHDVDEEHKRELLFGHSERLAVAFGIINTEPGTTIRVTKNIRICTDCHVAIKFISKITEREIIVRDNSRFHHFNRGNCSCGDYW 715          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIV-FYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAK---------AGRIYE---------------------------ARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLG-ACRVHSNVEIGEFVGFRLLQIEPENAGNYVILS 1275
            TL+      ++  + +++HA   +T  L   H    +++  Y N + L++A  +   +    V++W ++I  ++ +   S+AL  F++M  SG  P+   F +VL SC         G  +H  I++   +  ++ G++L++MYAK          G +++                            R VFE +P +DVVS   II+GYAQ G+ E+AL + R++    +  +  T +SVL   S    +  G+++H +V+R+ + S V + +SL+DMY+K   +  S R+F  +  R  ISWN+++ GY ++G   E ++LF+ M    KV+P +V F +V+  C+H      G +    +  G  G+   +     +VD+  + G ++ A +   +M      +    ++G A   H +  +  F   +   ++P       +L+
Sbjct:   10 TLIKNPTRIKSKSQAKQLHAQFIRTQSLS--HTSASIVISIYTNLKLLHEALLLFKTLKSPPVLAWKSVIRCFTDQSLFSKALASFVEMRASGRCPDHNVFPSVLKSCT-MMMDLRFGESVHGFIVRLGMDCDLYTGNALMNMYAKLLGMGSKISVGNVFDEMPQRTSNSGDEDVKAETCIMPFGIDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTDLKPDSFTLSSVLPIFSEYVDVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTA-KVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIA--SALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLT 452          

Query:   82 EGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHV-----LRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSM-PERTVISWNAMLVGYSKH 876
            +G+ +H ++ +      +++ + L+  Y     + D++RV   +  R+ +SW ++++ Y + G  +EAL LF QM+ +  +P    F++V+ +CA  A    LG+Q+H  +++  F S+IF+ S+L+DMY+K G I  AR +F+ +   D VS TAII G+A  G   EA+ LF +++R+G+  N V + +VLTA S +  +D      N +     L +EL  Y     ++ D+  + G L  +      M  E T   W+ +L   S H
Sbjct:  260 KGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLA-TLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTKVYGLNQELEHYA----AVADLLGRAGKLEEAYNFISKMCVEPTGSVWSTLLSSCSVH 525          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCA-----GGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEA 498
            + +++  C +      G+++H ++ +  +   + + + L+  Y+ C  +  A+++ D M V + VSWTA+I  ++  G   EA++LF +M R G +PN+  F  VLT+C+       AWG+      +S+         +   +++ D+  +AG++ EA
Sbjct:  346 FSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGY-----FNSMTKVYGLNQELEHYAAVADLLGRAGKLEEA 499          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G EM F GY  LLN C+++RA R+GQRVHAHM KT YLP  +LRTRL++FY  C+CL DA++VLDEMP +NVVSWTAMIS YS+ G +SEAL +F +M+RS  +PNEFTFATVLTSC   + G  LG+QIH LI+K  ++SHIFVGSSLLDMYAKAG+I EAR +FECLPERDVVSCTAII+GYAQLGLDEEALE+F +L  EGM+ NYVTYAS+LTALSGLA LD G+Q H HVLRRELP Y VLQNSLIDMYSKCGNLSY+RR+FD+MPERT ISWNAMLVGYSKHG+G+EV++LF+LM++E +V+PD+VT LAVLSGCSHG MED GL  F  M  GE GT+P  EHYGC+VD+LGRAGR++EAFEFIK+M  +PTA + GSLLGACRVH +V+IGE VG RL++IEPENAGNYVILSNLYAS GRW  V NVR +M++KAV KEPGRSWI+ +Q LH FHA+DR+HPRR   +            AGYVPDL CVLYDVDEEQKEK+LLGHSEK+AL FGLIAT EG+P+RV KNLRICVDCHNFAK+ SK++ REVSLRDKNRFH IV G CSCGDYW
Sbjct:   43 MAMLGPEMGFHGYDALLNACLDKRALRDGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALTVFAEMMRSDGKPNEFTFATVLTSCIRAS-GLGLGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIKEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFHRLHSEGMSPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYARRLFDNMPERTAISWNAMLVGYSKHGLGREVLELFRLMRDEKRVKPDAVTLLAVLSGCSHGRMEDTGLNIFDGMVAGEYGTKPGTEHYGCIVDMLGRAGRIDEAFEFIKRMPSKPTAGVLGSLLGACRVHLSVDIGESVGRRLIEIEPENAGNYVILSNLYASAGRWADVNNVRAMMMQKAVTKEPGRSWIQHEQTLHYFHANDRTHPRREEVLAKMKEISIKMKQAGYVPDLSCVLYDVDEEQKEKMLLGHSEKLALTFGLIATGEGIPIRVFKNLRICVDCHNFAKIFSKVFEREVSLRDKNRFHQIVDGICSCGDYW 628          

Query:  508 FECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLF-KLMKEENKVRPDSVTFLAVLSGC----------------------SHGGMEDRGLEYFYEMAEGENGTE-----PELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFE---PTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIE-PENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVI 1350
            F   P   V+     IS     G  +EAL     L   G    +  Y ++L A     AL  G++VH H+++        L+  L+  Y KC  L  +R++ D MPE+ V+SW AM+  YS+ G   E + +F ++M+ + K  P+  TF  VL+ C                      SH  +    L+ + +  + +   E     PE +   C   + G A  G  EEA E   ++  E   P    + SLL A    + ++ G+     +L+ E P  A     L ++Y+  G     R + + M E+  I
Sbjct:   12 FSSSPTNYVLQTILPISQLCSNGRLQEALLEMAML---GPEMGFHGYDALLNACLDKRALRDGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALTVFAEMMRSDGK--PNEFTFATVLTSCIRASGLGLGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIKEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFHRLHSEGMSPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYARRLFDNMPERTAI 321          

Query:   46 LLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDA-------------------------------QRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRR--ELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +L  C   +AF+EGQ++H H+ K      +++ T LI  Y     L DA                               Q++ DE+PV++VVSW AMIS Y++ G   EAL LF  M+++   P+E T  TV+++CA      +LGRQ+H  I    F S++ + ++L+D+Y+K G +  A G+FE LP +DV+S   +I GY  + L +EAL LF+++ R G T N VT  S+L A + L A+D+GR +H ++ +R   + +   L+ SLIDMY+KCG++  + ++F+S+  +++ SWNAM+ G++ HG       LF  M++   ++PD +TF+ +LS CSH GM D G   F  M +    T P+LEHYGC++DLLG +G  +EA E I  M  EP   IW SLL AC++H NVE+GE     L++IEPEN G+YV+LSN+YAS GRW  V   R L+ +K + K PG S IE+D ++H F   D+ HPR                 AG+VPD   VL +++EE KE  L  HSEK+A+AFGLI+T  G  + ++KNLR+C +CH   KL+SKIY RE+  RD+ RFHH   G CSC DYW
Sbjct:  140 VLKSCAKSKAFKEGQQIHGHVLKLGCDLDLYVHTSLISMYVQNGRLEDAHKVFDKSPHRDVVSYTALIKGYASRGYIENAQKLFDEIPVKDVVSWNAMISGYAETGNYKEALELFKDMMKTNVRPDESTMVTVVSACAQSG-SIELGRQVHLWIDDHGFGSNLKIVNALIDLYSKCGELETACGLFERLPYKDVISWNTLIGGYTHMNLYKEALLLFQEMLRSGETPNDVTMLSILPACAHLGAIDIGRWIHVYIDKRLKGVTNASSLRTSLIDMYAKCGDIEAAHQVFNSILHKSLSSWNAMIFGFAMHGRADASFDLFSRMRKIG-IQPDDITFVGLLSACSHSGMLDLGRHIFRTMTQDYKMT-PKLEHYGCMIDLLGHSGLFKEAEEMINMMEMEPDGVIWCSLLKACKMHGNVELGESFAENLIKIEPENPGSYVLLSNIYASAGRWNEVAKTRALLNDKGMKKVPGCSSIEIDSVVHEFIIGDKFHPRNREIYGMLEEMEVLLEKAGFVPDTSEVLQEMEEEWKEGALRHHSEKLAIAFGLISTKPGTKLTIVKNLRVCRNCHEATKLISKIYKREIIARDRTRFHHFRDGVCSCNDYW 741          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFY---NNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAI-------------------------------ISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVH--SNVEIGEFVGFRLLQIEPEN 1251
            +LL+ C   ++ R    +HA M K       +  ++LI F     + E L  A  V   +   N++ W  M   ++       AL L++ M+  G  PN +TF  VL SCA     F  G+QIH  ++K   +  ++V +SL+ MY + GR+ +A  VF+  P RDVVS TA+                               ISGYA+ G  +EALELF+ + +  +  +  T  +V++A +   +++LGRQVH  +      S + + N+LID+YSKCG L  +  +F+ +P + VISWN ++ GY+   + KE + LF+ M    +  P+ VT L++L  C+H G  D G      + +   G          ++D+  + G +E A +    +    + + W +++    +H  ++     F   R + I+P++
Sbjct:   38 SLLHNCKTLQSLRI---IHAQMIKIGLHNTNYALSKLIEFCILSPHFEGLPYAISVFKTIQEPNLLIWNTMFRGHALSSDPVSALKLYVCMISLGLLPNSYTFPFVLKSCAKSK-AFKEGQQIHGHVLKLGCDLDLYVHTSLISMYVQNGRLEDAHKVFDKSPHRDVVSYTALIKGYASRGYIENAQKLFDEIPVKDVVSWNAMISGYAETGNYKEALELFKDMMKTNVRPDESTMVTVVSACAQSGSIELGRQVHLWIDDHGFGSNLKIVNALIDLYSKCGELETACGLFERLPYKDVISWNTLIGGYTHMNLYKEALLLFQEMLRSGET-PNDVTMLSILPACAHLGAIDIGRWIHVYIDKRLKGVTNASSLRTSLIDMYAKCGDIEAAHQVFNSI-LHKSLSSWNAMIFGFAMHGRADASFDLFSRMRKIGIQPDD 470          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR-------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y  L+  C++ RA  EG  +  H+    + P M L   LI  Y     LNDA ++ D+MP RNV+SWT MISAYSK     +AL L + MLR    PN +T+++VL SC G +   D+ R +H  IIK   ES +FV S+L+D++AK G   +A  VF+ +   D +   +II G+AQ    + ALELF++++R G  +   T  SVL A +GLA L+LG Q H H+++ +    ++L N+L+DMY KCG+L  + R+F+ M ER VI+W+ M+ G +++G  +E +KLF+ MK     +P+ +T + VL  CSH G+ + G  YF  M +   G +P  EHYGC++DLLG+AG++++A + + +M  EP A  W +LLGACRV  N+ + E+   +++ ++PE+AG Y +LSN+YA+  +W+ V  +R  M ++ + KEPG SWIE+++ +H F   D SHP+             R  G+ GYVP+   VL D++ EQ E  L  HSEK+ALAFGL+  P    +R+ KNLRIC DCH F KL SK+  R + +RD  R+HH   G CSCGDYW
Sbjct:   64 YSELIKCCISNRAVHEGNLICRHLYFNGHRPMMFLVNVLINMYVKFNLLNDAHQLFDQMPQRNVISWTTMISAYSKCKIHQKALELLVLMLRDNVRPNVYTYSSVLRSCNGMS---DV-RMLHCGIIKEGLESDVFVRSALIDVFAKLGEPEDALSVFDEMVTGDAIVWNSIIGGFAQNSRSDVALELFKRMKRAGFIAEQATLTSVLRACTGLALLELGMQAHVHIVKYDQD--LILNNALVDMYCKCGSLEDALRVFNQMKERDVITWSTMISGLAQNGYSQEALKLFERMKSSG-TKPNYITIVGVLFACSHAGLLEDGWYYFRSMKK-LYGIDPVREHYGCMIDLLGKAGKLDDAVKLLNEMECEPDAVTWRTLLGACRVQRNMVLAEYAAKKVIALDPEDAGTYTLLSNIYANSQKWDSVEEIRTRMRDRGIKKEPGCSWIEVNKQIHAFIIGDNSHPQIVEVSKKLNQLIHRLTGI-GYVPETNFVLQDLEGEQMEDSLRHHSEKLALAFGLMTLPIEKVIRIRKNLRICGDCHVFCKLASKLEIRSIVIRDPIRYHHFQDGKCSCGDYW 630          

Query:  544 TAIISGYAQLGLDEE---ALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEI 1206
            T ++S + +L    +   A++    LQ  G+ ++  TY+ ++       A+  G  +  H+        + L N LI+MY K   L+ + ++FD MP+R VISW  M+  YSK  + ++ ++L  LM  +N VRP+  T+ +VL  C+  GM D  + +   + E   G E ++     ++D+  + G  E+A     +M     A +W S++G    +S  ++
Sbjct:   27 TLLLSEFTRLCYQRDLPRAMKAMDSLQSHGLWADSATYSELIKCCISNRAVHEGNLICRHLYFNGHRPMMFLVNVLINMYVKFNLLNDAHQLFDQMPQRNVISWTTMISAYSKCKIHQKALELLVLMLRDN-VRPNVYTYSSVLRSCN--GMSDVRMLHCGIIKE---GLESDVFVRSALIDVFAKLGEPEDALSVFDEM-VTGDAIVWNSIIGGFAQNSRSDV 243          

Query:   85 GQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTF------ATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGR--IYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQL-QREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            G++ H       Y   + + + LIV Y+ C  L DA++V DE+P RN+VSWT+MI  Y   G A +A++LF  +L    + ++  F       +V+++C+       L   IHS +IK  F+  + VG++LLD YAK G   +  AR +F+ + ++D VS  +I+S YAQ G+  EA E+FR+L + + +T N +T ++VL A+S   AL +G+ +H+ V+R  L   V++  S+IDMY KCG +  +R+ FD M  + V SW AM+ GY  HG   + ++LF  M +   VRP+ +TF++VL+ CSH G+   G  +F  M +G  G EP LEHYGC+VDLLGRAG +++A++ I++M+ +P + IW SLL ACR+H NVE+ E    RL +++  N G Y++LS++YA  GRW+ V  VR +M  + ++K PG S +EL+  +H F   D  HP+R +              AGYV +   V +DVDEE+KE  L  HSEK+A+AFG++ T  G  V V+KNLR+C DCHN  KL+SKI  RE  +RD  RFHH   G CSCGDYW
Sbjct:   95 GKQTHQQAFVFGYQSDIFVSSALIVMYSTCGKLEDARKVFDEIPKRNIVSWTSMIRGYDLNGNALDAVSLFKDLLVDENDDDDAMFLDSMGLVSVISACSRVP-AKGLTESIHSFVIKRGFDRGVSVGNTLLDAYAKGGEGGVAVARKIFDQIVDKDRVSYNSIMSVYAQSGMSNEAFEVFRRLVKNKVVTFNAITLSTVLLAVSHSGALRIGKCIHDQVIRMGLEDDVIVGTSIIDMYCKCGRVETARKAFDRMKNKNVRSWTAMIAGYGMHGHAAKALELFPAMIDSG-VRPNYITFVSVLAACSHAGLHVEGWRWFNAM-KGRFGVEPGLEHYGCMVDLLGRAGFLQKAYDLIQRMKMKPDSIIWSSLLAACRIHKNVELAEISVARLFELDSSNCGYYMLLSHIYADAGRWKDVERVRMIMKNRGLVKPPGFSLLELNGEVHVFLIGDEEHPQREKIYEFLAELNRKLLEAGYVSNTSSVCHDVDEEEKEMTLRVHSEKLAIAFGIMNTVPGSTVNVVKNLRVCSDCHNVIKLISKIVDREFVVRDAKRFHHFKDGGCSCGDYW 659          

Query:  223 NVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDL--GRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQL------QREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKC--GNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSN 1197
            +V SW ++I+  ++ G ++EAL  F  M +    P   +F   + +C+     FD+  G+Q H       ++S IFV S+L+ MY+  G++ +AR VF+ +P+R++VS T++I GY   G   +A+ LF+ L        + M  + +   SV++A S + A  L   +H+ V++R     V + N+L+D Y+K   G ++ +R+IFD + ++  +S+N+++  Y++ GM  E  ++F+ + +   V  +++T   VL   SH G    G     ++     G E ++     ++D+  + GRVE A +   +M+       W +++    +H +
Sbjct:   40 DVFSWNSVIADLARSGDSAEALLAFSSMRKLSLYPTRSSFPCAIKACSS---LFDIFSGKQTHQQAFVFGYQSDIFVSSALIVMYSTCGKLEDARKVFDEIPKRNIVSWTSMIRGYDLNGNALDAVSLFKDLLVDENDDDDAMFLDSMGLVSVISACSRVPAKGLTESIHSFVIKRGFDRGVSVGNTLLDAYAKGGEGGVAVARKIFDQIVDKDRVSYNSIMSVYAQSGMSNEAFEVFRRLVKNKVVTFNAITLSTVLLAVSHSGALRIGKCIHDQVI--RMGLEDDVIVGTSIIDMYCKCGRVETARKAFDRMK-NKNVRSWTAMIAGYGMHGH 368          

Query:  529 DVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFK-LMKEEN----KVRPDSVTFLAVLSGCS-----------HGGMEDRGLEYFYEMAE---------GENG-----------TEPELEHYGCVVDLLGRAGRVEEAFE----FIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPEN---AGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSW 1371
            DV S  ++I+  A+ G   EAL  F  +++  +     ++   + A S L  +  G+Q H         S + + ++LI MYS CG L  +R++FD +P+R ++SW +M+ GY  +G   + V LFK L+ +EN     +  DS+  ++V+S CS           H  +  RG +    +           GE G            + +   Y  ++ +  ++G   EAFE     +K       A    ++L A      + IG+ +  +++++  E+    G  +I  ++Y   GR E  R   + M  K V     RSW
Sbjct:   40 DVFSWNSVIADLARSGDSAEALLAFSSMRKLSLYPTRSSFPCAIKACSSLFDIFSGKQTHQQAFVFGYQSDIFVSSALIVMYSTCGKLEDARKVFDEIPKRNIVSWTSMIRGYDLNGNALDAVSLFKDLLVDENDDDDAMFLDSMGLVSVISACSRVPAKGLTESIHSFVIKRGFDRGVSVGNTLLDAYAKGGEGGVAVARKIFDQIVDKDRVSYNSIMSVYAQSGMSNEAFEVFRRLVKNKVVTFNAITLSTVLLAVSHSGALRIGKCIHDQVIRMGLEDDVIVGTSII--DMYCKCGRVETARKAFDRMKNKNV-----RSW 356          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEA 498
            T+L    +  A R G+ +H  + +      + + T +I  Y  C  +  A++  D M  +NV SWTAMI+ Y   G A++AL LF  M+ SG  PN  TF +VL +C+      +  R  +++  +   E  +     ++D+  +AG + +A
Sbjct:  292 TVLLAVSHSGALRIGKCIHDQVIRMGLEDDVIVGTSIIDMYCKCGRVETARKAFDRMKNKNVRSWTAMIAGYGMHGHAAKALELFPAMIDSGVRPNYITFVSVLAACSHAGLHVEGWRWFNAMKGRFGVEPGLEHYGCMVDLLGRAGFLQKA 443          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFD---LGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTS--NYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGVA------------GYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y  L+  C +R +  +  RVH H+          L T+LI  Y++   ++ A++V D+   R +  W A+  A +  G   E L L+ +M R G E + FT+  VL +C       +    G++IH+ + +  + SH+++ ++L+DMYA+ G +  A  VF  +P R+VVS +A+I+ YA+ G   EAL  FR++ RE   S  N VT  SVL A + LAAL+ G+ +H ++LRR L S + + ++L+ MY +CG L   +R+FD M +R V+SWN+++  Y  HG GK+ +++F+ M   N   P  VTF++VL  CSH G+ + G   F  M   ++G +P++EHY C+VDLLGRA R++EA + ++ MR EP   +WGSLLG+CR+H NVE+ E    RL  +EP+NAGNYV+L+++YA    W+ V+ V++L+  + + K PGR W+E+ + +++F + D  +P   +  A            GY+P    VLY+++ E+KE+++LGHSEK+ALAFGLI T +G P+R+ KNLR+C DCH F K +SK   +E+ +RD NRFH    G CSCGDYW
Sbjct:   80 YELLILCCGHRSSLSDALRVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTRKRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIGVESDRFTYTYVLKACVASECTVNHLMKGKEIHAHLTRRGYSSHVYIMTTLVDMYARFGCVDYASYVFGGMPVRNVVSWSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSVLQACASLAALEQGKLIHGYILRRGLDSILPVISALVTMYGRCGKLEVGQRVFDRMHDRDVVSWNSLISSYGVHGYGKKAIQIFEEMLA-NGASPTPVTFVSVLGACSHEGLVEEGKRLFETMWR-DHGIKPQIEHYACMVDLLGRANRLDEAAKMVQDMRTEPGPKVWGSLLGSCRIHGNVELAERASRRLFALEPKNAGNYVLLADIYAEAQMWDEVKRVKKLLEHRGLQKLPGRCWMEVRRKMYSFVSVDEFNPLMEQIHAFLVKLAEDMKEKGYIPQTKGVLYELETEEKERIVLGHSEKLALAFGLINTSKGEPIRITKNLRLCEDCHLFTKFISKFMEKEILVRDVNRFHRFKNGVCSCGDYW 657          

Query:  595 ELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGC 975
            +  R L +E   S   TY  ++      ++L    +VH H+L         L   LI MYS  G++ Y+R++FD   +RT+  WNA+    +  G G+EV+ L+  M     V  D  T+  VL  C
Sbjct:   64 QAIRVLSQESSPSQQ-TYELLILCCGHRSSLSDALRVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTRKRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIG-VESDRFTYTYVLKAC 188          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHH 1689
            Y TLL +C   +   +G+ VHAH+ ++ +   + +   L+  Y  C  L +A++V ++MP R+ V+WT +IS YS+     +AL  F QMLR G  PNEFT ++V+ + A    G   G Q+H   +K  F+S++ VGS+LLD+Y + G + +A+ VF+ L  R+ VS  A+I+G+A+    E+ALELF+ + R+G   ++ +YAS+  A S    L+ G+ VH ++++          N+L+DMY+K G++  +R+IFD + +R V+SWN++L  Y++HG GKE V  F+ M+    +RP+ ++FL+VL+ CSH G+ D G  Y YE+ + ++G  PE  HY  VVDLLGRAG +  A  FI++M  EPTAAIW +LL ACR+H N E+G +    + +++P++ G +VIL N+YAS GRW     VR+ M E  V KEP  SW+E++  +H F A+D  HP+R                 GYVPD   V+  VD++++E  L  HSEK+ALAF L+ TP G  + + KN+R+C DCH   KL SK+ GRE+ +RD NRFHH
Sbjct:   63 YNTLLKKCTVFKLLIQGRIVHAHILQSIFRHDIVMGNTLLNMYAKCGSLEEARKVFEKMPQRDFVTWTTLISGYSQHDRPCDALLFFNQMLRFGYSPNEFTLSSVIKAAAAERRGC-CGHQLHGFCVKCGFDSNVHVGSALLDLYTRYGLMDDAQLVFDALESRNDVSWNALIAGHARRSGTEKALELFQGMLRDGFRPSHFSYASLFGACSSTGFLEQGKWVHAYMIKSGEKLVAFAGNTLLDMYAKSGSIHDARKIFDRLAKRDVVSWNSLLTAYAQHGFGKEAVWWFEEMRRVG-IRPNEISFLSVLTACSHSGLLDEGWHY-YELMK-KDGIVPEAWHYVTVVDLLGRAGDLNRALRFIEEMPIEPTAAIWKALLNACRMHKNTELGAYAAEHVFELDPDDPGPHVILYNIYASGGRWNDAARVRKKMKESGVKKEPACSWVEIENAIHMFVANDERHPQREEIARKWEEVLAKIKELGYVPDTSHVIVHVDQQEREVNLQYHSEKIALAFALLNTPPGSTIHIKKNIRVCGDCHTAIKLASKVVGREIIVRDTNRFHH 621          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMP-VRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGL-AALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVG-GTCSCGDYW 1725
            M +  + +    + +++  C N +  R  +++H  + K  +L   ++RT L+V Y+ C  + DA R+  E+  V NVVSWTAMIS + +     EA++LF +M R G  PNEFT++ +LT     A       ++H+ ++KT +E    VG++LLD Y K G++ EA  VF  + ++D+V+ +A+++GYAQ G  E A+++F +L + G+  N  T++S+L   +   A++  G+Q H   ++  L S + + ++L+ MY+K GN+  +  +F    E+ ++SWN+M+ GY++HG   + + +FK MK+  KV+ D VTF+ V + C+H G+ + G +YF  M   +    P  EH  C+VDL  RAG++E+A + I+ M     + IW ++L ACRVH   E+G     +++ ++PE++  YV+LSN+YA  G W+    VR+LM E+ V KEPG SWIE+    ++F A DRSHP + +               GY PD   VL D+D+E KE VL  HSE++A+AFGLIATP+G P+ +IKNLR+C DCH   KL++KI  RE+ +RD NRFHH    G CSCGD+W
Sbjct:  286 MRLNYVRLSESSFASVIKLCANLKELRFTEQLHCSVVKYGFLFDQNIRTALMVAYSKCTAMLDALRLFKEIGCVGNVVSWTAMISGFLQNDGKEEAVDLFSEMKRKGVRPNEFTYSVILT-----ALPVISPSEVHAQVVKTNYERSSTVGTALLDAYVKLGKVEEAAKVFSGIDDKDIVAWSAMLAGYAQTGETEAAIKMFGELTKGGIKPNEFTFSSILNVCAATNASMGQGKQFHGFAIKSRLDSSLCVSSALLTMYAKKGNIESAEEVFKRQREKDLVSWNSMISGYAQHGQAMKALDVFKEMKKR-KVKMDGVTFIGVFAACTHAGLVEEGEKYFDIMVR-DCKIAPTKEHNSCMVDLYSRAGQLEKAMKVIENMPNPAGSTIWRTILAACRVHKKTELGRLAAEKIIAMKPEDSAAYVLLSNMYAESGDWQERAKVRKLMNERNVKKEPGYSWIEVKNKTYSFLAGDRSHPLKDQIYMKLEDLSTRLKDLGYEPDTSYVLQDIDDEHKEAVLAQHSERLAIAFGLIATPKGSPLLIIKNLRVCGDCHLVIKLIAKIEEREIVVRDSNRFHHFSSDGVCSCGDFW 868          

Query:   85 GQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMP-ERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLS 969
            G+++H    K  +L  + + T L+  Y       D ++V DEM  RNVV+WT +IS Y++     E L LF++M   GT+PN FTFA  L   A    G   G Q+H++++K   +  I V +SL+++Y K G + +AR +F+    + VV+  ++ISGYA  GLD EAL +F  ++   +  +  ++ASV+   + L  L    Q+H  V++        ++ +L+  YSKC  +  + R+F  +     V+SW AM+ G+ ++   +E V LF  MK +  VRP+  T+  +L+
Sbjct:  112 GRQLHCQCIKFGFLDDVSVGTSLVDTYMKGSNFKDGRKVFDEMKERNVVTWTTLISGYARNSMNDEVLTLFMRMQNEGTQPNSFTFAAALGVLAEEGVG-GRGLQVHTVVVKNGLDKTIPVSNSLINLYLKCGNVRKARILFDKTEVKSVVTWNSMISGYAANGLDLEALGMFYSMRLNYVRLSESSFASVIKLCANLKELRFTEQLHCSVVKYGFLFDQNIRTALMVAYSKCTAMLDALRLFKEIGCVGNVVSWTAMISGFLQNDGKEEAVDLFSEMKRKG-VRPNEFTYSVILT 405          

Query:  181 LNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSH 981
            L +A  + D+ P R+  S+ +++  +S+ G   EA  LFL + R G E +   F++VL   A        GRQ+H   IK  F   + VG+SL+D Y K     + R VF+ + ER+VV+ T +ISGYA+  +++E L LF ++Q EG   N  T+A+ L  L+       G QVH  V++  L   + + NSLI++Y KCGN+  +R +FD    ++V++WN+M+ GY+ +G+  E + +F  M+  N VR    +F +V+  C++
Sbjct:   43 LYNAHNLFDKSPGRDRESYISLLFGFSRDGRTQEAKRLFLNIHRLGMEMDCSIFSSVLKVSATLCDEL-FGRQLHCQCIKFGFLDDVSVGTSLVDTYMKGSNFKDGRKVFDEMKERNVVTWTTLISGYARNSMNDEVLTLFMRMQNEGTQPNSFTFAAALGVLAEEGVGGRGLQVHTVVVKNGLDKTIPVSNSLINLYLKCGNVRKARILFDKTEVKSVVTWNSMISGYAANGLDLEALGMFYSMR-LNYVRLSESSFASVIKLCAN 307          

Query:  478 AGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHS-NVE-IGEFVGFRLLQIEPENAGNYVILS-NLYASV 1293
            + R+Y A  +F+  P RD  S  +++ G+++ G  +EA  LF  + R GM  +   ++SVL   + L     GRQ+H   ++      V +  SL+D Y K  N    R++FD M ER V++W  ++ GY+++ M  EV+ LF  M+ E   +P+S TF A L   +  G+  RGL+    +   +NG +  +     +++L  + G V +A     K   + +   W S++     +  ++E +G F   RL         NYV LS + +ASV
Sbjct:   40 SSRLYNAHNLFDKSPGRDRESYISLLFGFSRDGRTQEAKRLFLNIHRLGMEMDCSIFSSVLKVSATLCDELFGRQLHCQCIKFGFLDDVSVGTSLVDTYMKGSNFKDGRKVFDEMKERNVVTWTTLISGYARNSMNDEVLTLFMRMQNEG-TQPNSFTFAAALGVLAEEGVGGRGLQVHTVVV--KNGLDKTIPVSNSLINLYLKCGNVRKARILFDKTEVK-SVVTWNSMISGYAANGLDLEALGMFYSMRL---------NYVRLSESSFASV 301          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPP-MHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRS-GTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQ-----------REGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKM-RFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M ++G+E       ++L  C +    R G+ +HA+  K   L     + + L+  Y NC+ +   +RV D M  R +  W AMI+ YS+     EAL LF+ M  S G   N  T A V+ +C      F     IH  ++K   +   FV ++L+DMY++ G+I  A  +F  + +RD+V+   +I+GY      E+AL L  ++Q           R  +  N +T  ++L + + L+AL  G+++H + ++  L + V + ++L+DMY+KCG L  SR++FD +P++ VI+WN +++ Y  HG G+E + L ++M  +  V+P+ VTF++V + CSH GM D GL  FY M + + G EP  +HY CVVDLLGRAGR++EA++ +  M R    A  W SLLGA R+H+N+EIGE     L+Q+EP  A +YV+L+N+Y+S G W+    VR  M E+ V KEPG SWIE    +H F A D SHP+  +               GYVPD  CVL++V+E++KE +L GHSEK+A+AFG++ T  G  +RV KNLR+C DCH   K +SKI  RE+ LRD  RFH    GTCSCGDYW
Sbjct:  293 MVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSG-AFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQG-VKPNEVTFISVFAACSHSGMVDEGLRIFYVM-KPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYLETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCY-LPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAW--GFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRR-ELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEG---ENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL 1173
            M V G++     +  LL    + +    G+++HAH+ K  Y +  + +   L+  Y  C       +V D +  RN VSW ++IS+         AL  F  ML    EP+ FT  +V+T+C+      G  +G+Q+H+  ++ K E + F+ ++L+ MY K G++  ++ +      RD+V+   ++S   Q     EALE  R++  EG+  +  T +SVL A S L  L  G+++H + L+   L     + ++L+DMY  C  +   RR+FD M +R +  WNAM+ GYS++   KE + LF  M+E   +  +S T   V+  C   G   R      E   G   + G + +      ++D+  R G+++ A     KM  +     W +++
Sbjct:   88 MIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLR-KGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSR-----KEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKME-DRDLVTWNTMI 478          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLII-KTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREG-MTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHP------------RRHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +LL+ C     F  G  +H++  K      + +  +LI  Y     L D Q+V D M VR+++SW ++I AY        A++LF +M  S  +P+  T  + L S           R +    + K  F   I +G++++ MYAK G +  AR VF  LP  DV+S   IISGYAQ G   EA+E++  ++ EG + +N  T+ SVL A S   AL  G ++H  +L+  L   V +  SL DMY KCG L  +  +F  +P    + WN ++  +  HG G++ V LFK M +E  V+PD +TF+ +LS CSH G+ D G ++ +EM + + G  P L+HYGC+VD+ GRAG++E A +FIK M  +P A+IWG+LL ACRVH NV++G+     L ++EPE+ G +V+LSN+YAS G+WEGV  +R +   K + K PG S +E+D  +  F+  +++HP            +    + GYVPD   VL DV++++KE +L+ HSE++A+AF LIATP    +R+ KNLR+C DCH+  K +SKI  RE+ +RD NRFHH   G CSCGDYW
Sbjct:  252 SLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSRIQPDCLTLIS-LASILSQLGDIRACRSVQGFTLRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLLKNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIPRVNSVPWNTLIACHGFHGHGEKAVMLFKEMLDEG-VKPDHITFVTLLSACSHSGLVDEG-QWCFEMMQTDYGITPSLKHYGCMVDMYGRAGQLETALKFIKSMSLQPDASIWGALLSACRVHGNVDLGKIASEHLFEVEPEHVGYHVLLSNMYASAGKWEGVDEIRSIAHGKGLRKTPGWSSMEVDNKVEVFYTGNQTHPMYEEMYRELTALQAKLKMIGYVPDHRFVLQDVEDDEKEHILMSHSERLAIAFALIATPAKTTIRIFKNLRVCGDCHSVTKFISKITEREIIVRDSNRFHHFKNGVCSCGDYW 823          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRE-LPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVE 1203
            M   GL   +  + ++L  C   R   +G ++H    K  ++  +++   LI  Y+  + + +A+ + DEMPVR++ SW AMIS Y + G A EAL L      +G    +      L S    A  F+ G  IHS  IK   ES +FV + L+D+YA+ GR+ + + VF+ +  RD++S  +II  Y        A+ LF++++   +  + +T  S+ + LS L  +   R V    LR+      + + N+++ MY+K G +  +R +F+ +P   VISWN ++ GY+++G   E ++++ +M+EE ++  +  T+++VL  CS  G   +G++    +   +NG   ++     + D+ G+ GR+E+A     ++     +  W +L+     H + E
Sbjct:  144 MLSSGLTPDYRTFPSVLKAC---RTVIDGNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTL-----SNGLRAMDSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMRLSRIQPDCLTLISLASILSQLGDIRACRSVQGFTLRKGWFLEDITIGNAVVVMYAKLGLVDSARAVFNWLPNTDVISWNTIISGYAQNGFASEAIEMYNIMEEEGEIAANQGTWVSVLPACSQAGALRQGMKLHGRLL--KNGLYLDVFVVTSLADMYGKCGRLEDALSLFYQIP-RVNSVPWNTLIACHGFHGHGE 534          

Query:   25 KFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLF-LQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGG 987
            + +  +TL   C N    +  + +HA +  +  +  + +  +L+  Y     +  A+   D +  R+V +W  MIS Y + G +SE +  F L ML SG  P+  TF +VL +C         G +IH L +K  F   ++V +SL+ +Y++   +  AR +F+ +P RD+ S  A+ISGY Q G  +EAL L   L+      + VT  S+L+A +     + G  +H++ ++  L S + + N LID+Y++ G L   +++FD M  R +ISWN+++  Y  +      + LF+ M+  ++++PD +T +++ S  S  G
Sbjct:   53 EIDDVHTLFRYCTN---LQSAKCLHARLVVSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKACR----TVIDGNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTLSNGLR----AMDSVTVVSLLSACTEAGDFNRGVTIHSYSIKHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLISWNSIIKAYELNEQPLRAISLFQEMR-LSRIQPDCLTLISLASILSQLG 362          

Query:  400 IHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQ-LQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRP-DSVTFLAVLSGCSHGGMEDRGLE-YFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNV--EIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEK 1341
            +H+ ++ +K   ++ + + L+++Y   G +  AR  F+ +  RDV +   +ISGY + G   E +  F   +   G+T +Y T+ SVL A      +D G ++H   L+      V +  SLI +YS+   +  +R +FD MP R + SWNAM+ GY + G  KE + L       N +R  DSVT +++LS C+  G  +RG+  + Y +   ++G E EL     ++DL    GR+ +  +   +M      + W S++ A  ++      I  F   RL +I+P+     + L+++ + +G     R+V+   + K
Sbjct:   73 LHARLVVSKQIQNVCISAKLVNLYCYLGNVALARHTFDHIQNRDVYAWNLMISGYGRAGNSSEVIRCFSLFMLSSGLTPDYRTFPSVLKACR--TVID-GNKIHCLALKFGFMWDVYVAASLIHLYSRYKAVGNARILFDEMPVRDMGSWNAMISGYCQSGNAKEALTL------SNGLRAMDSVTVVSLLSACTEAGDFNRGVTIHSYSI---KHGLESELFVSNKLIDLYAEFGRLRDCQKVFDRMYVRDLIS-WNSIIKAYELNEQPLRAISLFQEMRLSRIQPD-CLTLISLASILSQLGDIRACRSVQGFTLRK 377          

Query:  181 LNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            ++  +RV + MP ++VVS+  +I+ Y++ G   +AL +  +M  +  +P+ FT ++VL   +        G++IH  +I+   +S +++GSSL+DMYAK+ RI ++  VF  L  RD +S  ++++GY Q G   EAL LFRQ+    +    V ++SV+ A + LA L LG+Q+H +VLR    S + + ++L+DMYSKCGN+  +R+IFD M     +SW A+++G++ HG G E V LF+ MK +  V+P+ V F+AVL+ CSH G+ D    YF  M +   G   ELEHY  V DLLGRAG++EEA+ FI KM  EPT ++W +LL +C VH N+E+ E V  ++  ++ EN G YV++ N+YAS GRW+ +  +R  M +K + K+P  SWIE+    H F + DRSHP   +               GYV D   VL+DVDEE K ++L GHSE++A+AFG+I T  G  +RV KN+RIC DCH   K +SKI  RE+ +RD +RFHH   G CSCGDYW
Sbjct:  192 IDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTDLKPDSFTLSSVLPIFSEYV-DVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQG-VKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTK-VYGLNQELEHYAAVADLLGRAGKLEEAYNFISKMCVEPTGSVWSTLLSSCSVHKNLELAEKVAEKIFTVDSENMGAYVLMCNMYASNGRWKEMAKLRLRMRKKGLRKKPACSWIEMKNKTHGFVSGDRSHPSMDKINEFLKAVMEQMEKEGYVADTSGVLHDVDEEHKRELLFGHSERLAVAFGIINTEPGTTIRVTKNIRICTDCHVAIKFISKITEREIIVRDNSRFHHFNRGNCSCGDYW 715          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIV-FYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAK---------AGRIYE---------------------------ARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLG-ACRVHSNVEIGEFVGFRLLQIEPENAGNYVILS 1275
            TL+      ++  + +++HA   +T  L   H    +++  Y N + L++A  +   +    V++W ++I  ++ +   S+AL  F++M  SG  P+   F +VL SC         G  +H  I++   +  ++ G++L++MYAK          G +++                            R VFE +P +DVVS   II+GYAQ G+ E+AL + R++    +  +  T +SVL   S    +  G+++H +V+R+ + S V + +SL+DMY+K   +  S R+F  +  R  ISWN+++ GY ++G   E ++LF+ M    KV+P +V F +V+  C+H      G +    +  G  G+   +     +VD+  + G ++ A +   +M      +    ++G A   H +  +  F   +   ++P       +L+
Sbjct:   10 TLIKNPTRIKSKSQAKQLHAQFIRTQSLS--HTSASIVISIYTNLKLLHEALLLFKTLKSPPVLAWKSVIRCFTDQSLFSKALASFVEMRASGRCPDHNVFPSVLKSCT-MMMDLRFGESVHGFIVRLGMDCDLYTGNALMNMYAKLLGMGSKISVGNVFDEMPQRTSNSGDEDVKAETCIMPFGIDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTDLKPDSFTLSSVLPIFSEYVDVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTA-KVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIA--SALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLT 452          

Query:   82 EGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHV-----LRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSM-PERTVISWNAMLVGYSKH 876
            +G+ +H ++ +      +++ + L+  Y     + D++RV   +  R+ +SW ++++ Y + G  +EAL LF QM+ +  +P    F++V+ +CA  A    LG+Q+H  +++  F S+IF+ S+L+DMY+K G I  AR +F+ +   D VS TAII G+A  G   EA+ LF +++R+G+  N V + +VLTA S +  +D      N +     L +EL  Y     ++ D+  + G L  +      M  E T   W+ +L   S H
Sbjct:  260 KGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLA-TLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTKVYGLNQELEHYA----AVADLLGRAGKLEEAYNFISKMCVEPTGSVWSTLLSSCSVH 525          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCA-----GGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEA 498
            + +++  C +      G+++H ++ +  +   + + + L+  Y+ C  +  A+++ D M V + VSWTA+I  ++  G   EA++LF +M R G +PN+  F  VLT+C+       AWG+      +S+         +   +++ D+  +AG++ EA
Sbjct:  346 FSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGY-----FNSMTKVYGLNQELEHYAAVADLLGRAGKLEEA 499          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+QG E+KF+GY  LLNECVN+RA REGQRVHAHM KTCYLPP++L TRLI+ Y  CECL  A+ V DEM  RNVVSWTAMIS YS+RG ASEAL+LF+QMLRS TEPNEFTFATVL+SC G + GF+LGRQIHS I K  +E+HIFVGSSLLDMYAKAGRI+EARGVFECLPERDVVSCTAIISGYAQLGLDEEALELF +LQREGM+SNYVTYAS+LTALSGLAALD G+QVH+HVLR ELP YVVLQNSLIDMYSKCGNL+Y+R+IF++MP RTVISWNAMLVGYSKHG G EVVKLFKLM+EENKV+PDSVTFLAVLSGCSHGG+ED+GLE F EM  G +  E  +EHYGCV+DLLGRAGRVEEAFE IKKM FEPTAAIWGSLLGACRVHSN  IGEFVG RLL+IEPENAGNYVILSNLYAS GRWE VRNVRELM+EKAVIKEPGRSWIELDQ +HTF+ASDRSHPRR                +GYVPD  CVLYDVDEEQKEK+LLGHSEK+ALAFGLI+T EGVP+RVIKNLRICVDCHNFAK VSK+YGR+VS+RDKNRFHH+ GG CSCGDYW
Sbjct:    1 MAIQGPEIKFDGYNMLLNECVNKRAVREGQRVHAHMIKTCYLPPVYLSTRLIILYTKCECLGCARHVFDEMRERNVVSWTAMISGYSQRGFASEALHLFVQMLRSDTEPNEFTFATVLSSCTGFS-GFELGRQIHSHIFKRNYENHIFVGSSLLDMYAKAGRIHEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFCRLQREGMSSNYVTYASLLTALSGLAALDHGKQVHSHVLRCELPFYVVLQNSLIDMYSKCGNLNYARKIFNNMPVRTVISWNAMLVGYSKHGKGIEVVKLFKLMREENKVKPDSVTFLAVLSGCSHGGLEDKGLEMFDEMMNGGDEIEAGIEHYGCVIDLLGRAGRVEEAFELIKKMPFEPTAAIWGSLLGACRVHSNTNIGEFVGCRLLEIEPENAGNYVILSNLYASAGRWEDVRNVRELMMEKAVIKEPGRSWIELDQTIHTFYASDRSHPRREEVFLKVRELLVKFKESGYVPDQSCVLYDVDEEQKEKILLGHSEKLALAFGLISTSEGVPLRVIKNLRICVDCHNFAKFVSKVYGRQVSIRDKNRFHHVAGGICSCGDYW 586          

Query:   46 LLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR-------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            L+  C+ RRA + G+R+H H+    ++P   L   LI  Y     L+DAQ V D+MP RNVVSWT MISAYS      +AL   + MLR G  PN FT+++VL +C G    F+L RQ+H  IIK   +S +FV S+L+D+Y++ G +  A  VF+ +   D+V  ++II+G+AQ    +EAL LF++++R G  +   T  SVL A +GLA L+LGRQVH HVL+ +    ++L N+L+DMY KCG+L  +  +F  M E+ VISW+ M+ G +++G  KE +KLF+ MK    ++P+ VT + VL  CSH G+ + GL YF+ M E   G +P  EHYGC++DLLGRAGR+ EA + I +M  EP A  W +LL ACRVH NV++      ++L+++P++AG YV+LSN+YA+  RW  V  VR  M  + + KEPG SWIE+ + +H F   DRSHP+             +  GV GYVPD   VL D++ EQ +  L  HSEK+A+ FGL++ P G  +R+ KNLRIC DCH F KL++K+  R + +RD  R+HH   G CSCGD+W
Sbjct:    8 LIKCCLARRAIQHGKRIHVHLISNGHVPKTFLINILINMYVKFGLLHDAQDVFDKMPDRNVVSWTTMISAYSAAKLNDKALEFLVLMLREGVRPNMFTYSSVLRACDGL---FNL-RQLHCCIIKIGLDSDVFVRSALIDVYSRWGELENALRVFDEMVTGDLVVWSSIIAGFAQNSDGDEALRLFKRMKRAGFLAQQTTLTSVLRACTGLALLELGRQVHVHVLKYDQD--LILNNALLDMYCKCGSLEDANAVFVRMVEKDVISWSTMIAGLAQNGYSKEALKLFESMKVLG-IKPNYVTIVGVLFACSHAGLVEEGLYYFHSMKE-LFGIDPGREHYGCMIDLLGRAGRLSEAVDLINEMECEPDAVTWRALLNACRVHRNVDVAIHAAKQILRLDPQDAGTYVLLSNIYANTQRWNDVAEVRRTMTNRGIKKEPGCSWIEVSKQIHAFILGDRSHPQIREINIQLNQLIYKLMGV-GYVPDTNFVLQDLEGEQMQDSLRYHSEKLAIVFGLMSLPRGQTIRIRKNLRICGDCHLFTKLLAKMEQRIIVIRDPVRYHHFQDGLCSCGDFW 571          

Query:  337 TFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLG--ACRVHSNVEIGEFVGFRLLQIEPENAGNYVIL 1272
            T ++ L  C         G++IH  +I        F+ + L++MY K G +++A+ VF+ +P+R+VVS T +IS Y+   L+++ALE    + REG+  N  TY+SVL A  GL  L   RQ+H  +++  L S V ++++LID+YS+ G L  + R+FD M    ++ W++++ G++++  G E ++LFK MK    +     T  +VL  C+   + + G +    + +     + +L     ++D+  + G +E+A     +M  E     W +++   A   +S   +  F   ++L I+P    NYV +
Sbjct:    3 TISSKLIKCCLARRAIQHGKRIHVHLISNGHVPKTFLINILINMYVKFGLLHDAQDVFDKMPDRNVVSWTTMISAYSAAKLNDKALEFLVLMLREGVRPNMFTYSSVLRACDGLFNL---RQLHCCIIKIGLDSDVFVRSALIDVYSRWGELENALRVFDEMVTGDLVVWSSIIAGFAQNSDGDEALRLFKRMKRAGFL-AQQTTLTSVLRACTGLALLELGRQVHVHVLK----YDQDLILNNALLDMYCKCGSLEDANAVFVRM-VEKDVISWSTMIAGLAQNGYSKEALKLFESMKVLGIKP----NYVTI 303          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHP--RRHRGV----------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M + G +     + ++L  CV    F  G+ VH    KT YL  + +   LI  Y     ++DA +V +EMP  +V+ W+ MI+ Y++   + EA+ +F +M R    PN+FT A++L +CA       LG QIH  ++K   + ++FV ++L+DMYAK GR+  +  +F   P    VS   +I GY Q G  E+AL LF+ +    +    VTY+SVL A +G+AAL+ G Q+H+  ++       V+ N+LIDMY+KCGN+  +R +FD + E   +SWNAM+ GYS HG+  E +K F+ M  E + +PD VTF+ +LS CS+ G+ DRG  YF  M E E   EP  EHY C+V LLGR+G +++A + + ++ FEP+  +W +LL AC +H++VE+G     R+L+IEPE+   +V+LSN+YA+  RW  V ++R  M  K + KEPG SWIE    +H F   D SHP  +   G+           GYVPD   VL DV++  KE+ L  HSE++ALA+GLI TP   P+R+IKNLRIC DCH   KL+SKI  R++ +RD NRFHH   G CSCGDYW
Sbjct:  237 MRIVGFKPNNFTFASVLKACVGLEVFNVGKAVHGCAFKTSYLEELFVGVELIDLYIKSGDVDDALQVFEEMPKDDVIPWSFMIARYAQSEQSEEAIEMFCRMRRGLVLPNQFTLASLLQACASLV-DLQLGNQIHCHVVKVGLDMNVFVSNALMDMYAKCGRMENSLQLFSESPNCTDVSWNTVIVGYVQAGNGEKALILFKDMLECQVQGTEVTYSSVLRACAGIAALEPGSQIHSLSVKTIYDKNTVVGNALIDMYAKCGNIKDARLVFDMLREHDQVSWNAMISGYSVHGLYGEALKTFESML-ETECKPDKVTFVGILSACSNAGLLDRGQAYFKSMVE-EYDIEPCAEHYTCMVWLLGRSGHLDKAAKLVHEIPFEPSVMVWRALLSACVIHNDVELGRISAQRVLEIEPEDEATHVLLSNIYANARRWGNVASIRTSMKRKGIRKEPGLSWIENQGRVHYFSVGDTSHPDTKLINGMLEWLNMKARNEGYVPDFSSVLLDVEDVDKEQRLWVHSERLALAYGLIRTPSISPLRIIKNLRICADCHAAIKLISKIVQRDIIIRDMNRFHHFHEGICSCGDYW 820          

Query:   10 QGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVH 1191
            +G E+    + T+L   V+    + G  VHA + K  +     + T LI  Y+ C     A++V D +  +++VSWT M++ Y +  C  E+L LF +M   G +PN FTFA+VL +C  G   F++G+ +H    KT +   +FVG  L+D+Y K+G + +A  VFE +P+ DV+  + +I+ YAQ    EEA+E+F +++R  +  N  T AS+L A + L  L LG Q+H HV++  L   V + N+L+DMY+KCG +  S ++F   P  T +SWN ++VGY + G G++ + LFK M  E +V+   VT+ +VL  C+     + G +        +   +        ++D+  + G +++A   +  M  E     W +++    VH
Sbjct:  139 EGHELNPFVFSTVLKLLVSAEWAKLGFSVHACVYKLGFDSDAFVGTALIDCYSVCGYAECARQVFDAIEYKDMVSWTGMVACYVENECFEESLKLFSRMRIVGFKPNNFTFASVLKACV-GLEVFNVGKAVHGCAFKTSYLEELFVGVELIDLYIKSGDVDDALQVFEEMPKDDVIPWSFMIARYAQSEQSEEAIEMFCRMRRGLVLPNQFTLASLLQACASLVDLQLGNQIHCHVVKVGLDMNVFVSNALMDMYAKCGRMENSLQLFSESPNCTDVSWNTVIVGYVQAGNGEKALILFKDML-ECQVQGTEVTYSSVLRACAGIAALEPGSQ--IHSLSVKTIYDKNTVVGNALIDMYAKCGNIKDA-RLVFDMLREHDQVSWNAMISGYSVH 527          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKK 1131
            Y +LL  C+       G+ +H  + K      +     L+ FY   + L DA ++ DEMP RN VS+  +I  YS+    SEA+ LF ++   G E N F F+TVL       W   LG  +H+ + K  F+S  FVG++L+D Y+  G    AR VF+ +  +D+VS T +++ Y +    EE+L+LF +++  G   N  T+ASVL A  GL   ++G+ VH    +      + +   LID+Y K G++  + ++F+ MP+  VI W+ M+  Y++    +E +++F  M+    V P+  T  ++L  C+   + D  L         + G +  +     ++D+  + GR+E + +   +
Sbjct:   47 YGSLLQSCIRNGDCATGKYLHCEIIKKGNCLDLFANNILLNFYVKYDSLPDAAKLFDEMPDRNTVSFVTLIQGYSQCLRFSEAIGLFSRLQGEGHELNPFVFSTVLKLLVSAEWA-KLGFSVHACVYKLGFDSDAFVGTALIDCYSVCGYAECARQVFDAIEYKDMVSWTGMVACYVENECFEESLKLFSRMRIVGFKPNNFTFASVLKACVGLEVFNVGKAVHGCAFKTSYLEELFVGVELIDLYIKSGDVDDALQVFEEMPKDDVIPWSFMIARYAQSEQSEEAIEMFCRMR-RGLVLPNQFTLASLLQACA--SLVDLQLGNQIHCHVVKVGLDMNVFVSNALMDMYAKCGRMENSLQLFSE 407          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFY-NNCECLN------------------------------DAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLR--RELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M   G E     + ++   C   R   EG++VHAH+ K        + T LI  Y  N E +N                              +A+ + DE+PVR+VVSW AMIS Y++ G   EA+  F +M R+   PN  T  +VL++CA       LG  + S I      S+I + + L+DMY K G + EA  +FE + +++VVS   +I GY  +   +EAL LFR++ +  +  N VT+ S+L A + L ALDLG+ VH +V +  + + + V L  SLIDMY+KCG+L+ ++RIFD M  +++ +WNAM+ G++ HG     + LF  M  E  V PD +TF+ VL+ C H G+   G  YF  M + +    P+L HYGC++DL GRAG  +EA   +K M  +P  AIW SLLGACR+H  +E+ E V   L ++EPEN   YV+LSN+YA  GRWE V  +R  + +  + K PG S IE+D ++H F   D+ HP+ +               AG+VPD   VLYD+DEE KE VL  HSEK+A+AFGLI+T  G  +R++KNLR+C +CH+  KL+SKI+ RE+  RD+NRFHH   G+CSC DYW
Sbjct:   88 MISSGTEPNEYTFPSIFKSCTKIRGAHEGKQVHAHVLKLGLEHNAFVHTSLINMYAQNGELVNARLVFDKSSMRDAVSFTALITGYASKGFLDEARELFDEIPVRDVVSWNAMISGYAQSGRVEEAMAFFEEMRRAKVTPNVSTMLSVLSACAQSGSSLQLGNWVRSWIEDRGLGSNIRLVNGLIDMYVKCGDLEEASNLFEKIQDKNVVSWNVMIGGYTHMSCYKEALGLFRRMMQSNIDPNDVTFLSILPACANLGALDLGKWVHAYVDKNMKSMKNTVALWTSLIDMYAKCGDLAAAKRIFDCMNTKSLATWNAMISGFAMHGHTDTALGLFSRMTSEGFV-PDDITFVGVLTACKHAGLLSLGRRYFSSMIQ-DYKVSPKLPHYGCMIDLFGRAGLFDEAETLVKNMEMKPDGAIWCSLLGACRIHRRIELAESVAKHLFELEPENPSAYVLLSNIYAGAGRWEDVAKIRTRLNDNRMKKVPGCSSIEVDSVVHEFLVGDKVHPQSNEIYKMLDEIDMRLEKAGFVPDTSEVLYDMDEEWKEGVLSHHSEKLAIAFGLISTKPGTTIRIMKNLRVCGNCHSATKLISKIFNREIIARDRNRFHHFKDGSCSCKDYW 705          

Query:  154 IVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASE----ALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAI-------------------------------ISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALS-GLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVE 1203
            +   +NC+ L   +++  ++    + +    +S   +   +SE    AL  ++ M+ SGTEPNE+TF ++  SC     G   G+Q+H+ ++K   E + FV +SL++MYA+ G +  AR VF+    RD VS TA+                               ISGYAQ G  EEA+  F +++R  +T N  T  SVL+A +   ++L LG  V + +  R L S + L N LIDMY KCG+L  +  +F+ + ++ V+SWN M+ GY+     KE + LF+ M + N + P+ VTFL++L  C++ G  D G      + +     +  +  +  ++D+  + G +  A      M  + + A W +++    +H + +
Sbjct:   34 LTLLSNCKTLQTLKQIHSQIIKTGLHNTHFALSKLIEGLSSSESPFLALEYYVHMISSGTEPNEYTFPSIFKSCTK-IRGAHEGKQVHAHVLKLGLEHNAFVHTSLINMYAQNGELVNARLVFDKSSMRDAVSFTALITGYASKGFLDEARELFDEIPVRDVVSWNAMISGYAQSGRVEEAMAFFEEMRRAKVTPNVSTMLSVLSACAQSGSSLQLGNWVRSWIEDRGLGSNIRLVNGLIDMYVKCGDLEEASNLFEKIQDKNVVSWNVMIGGYTHMSCYKEALGLFRRMMQSN-IDPNDVTFLSILPACANLGALDLGKWVHAYVDKNMKSMKNTVALWTSLIDMYAKCGDLAAAKRIFDCMNTK-SLATWNAMISGFAMHGHTD 416          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCA-------------------------------SEALNLFLQMLRS-GTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y TL+  C+  R  ++G++VH H+  + ++P + +  RL+  Y  C+ L D+Q++ DEMP R++ SW  +IS Y+K G                                 +EAL LF  M RS  ++ N+FT ++ L + A       +G++IH  I++T  +S   V S+L DMY K G I EAR +F+ + +RD+V+ TA+I  Y Q G  +E  +LF  L R G+  N  T++ VL A +   + +LG++VH ++ R     +    ++L+ MYSKCGN+  + R+F   P+  + SW +++ GY+++G   E ++ F+L+ +    +PD +TF+ VLS C+H G+ D+GL+YF+ + E + G     +HY C++DLL R+G+ +EA   I KM  +P   +W SLLG CR+H N+++ +     L +IEPEN   YV L+N+YA+ G W  V  +R+ M ++ V+K+PG SWI + + +H F   D SHP+            +     G+VPD   VL+DV++EQKE+ L  HSEK+A+AFG+I+TPEG P++V KNLR CVDCH   K +SKI  R++ +RD NRFH    G CSC DYW
Sbjct:   73 YSTLIQSCIKSRLLQQGKKVHQHIKLSGFVPGLFILNRLLEMYAKCDSLMDSQKLFDEMPERDLCSWNILISGYAKMGLLQEAKSLFDKMPERDNFSWTAMISGYVRHDRPNEALELFRMMKRSDNSKSNKFTVSSALAAAAAVPC-LRIGKEIHGYIMRTGLDSDEVVWSALSDMYGKCGSIEEARHIFDKMVDRDIVTWTAMIDRYFQDGRRKEGFDLFADLLRSGIRPNEFTFSGVLNACANQTSEELGKKVHGYMTRVGFDPFSFAASALVHMYSKCGNMVSAERVFKETPQPDLFSWTSLIAGYAQNGQPDEAIRYFELLVKSG-TQPDHITFVGVLSACAHAGLVDKGLDYFHSIKE-QYGLTHTADHYACIIDLLARSGQFDEAENIISKMSMKPDKFLWASLLGGCRIHGNLKLAQRAAEALFEIEPENPATYVTLANIYATAGMWSEVAKIRKTMDDRGVVKKPGLSWIAIKRDVHVFLVGDDSHPKSKEINEFLGKLSKRMKEEGFVPDTNFVLHDVEDEQKEQNLSYHSEKLAVAFGIISTPEGTPIKVFKNLRTCVDCHTAIKFISKITNRKIIVRDSNRFHFFEDGHCSCRDYW 676          

Query:  271 CASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGL-------------------------------DEEALELFRQLQR-EGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL 1173
            C    L   LQ+L    +P+   ++T++ SC         G+++H  I  + F   +F+ + LL+MYAK   + +++ +F+ +PERD+ S   +ISGYA++GL                                 EALELFR ++R +   SN  T +S L A + +  L +G+++H +++R  L S  V+ ++L DMY KCG++  +R IFD M +R +++W AM+  Y + G  KE   LF  +     +RP+  TF  VL+ C++   E+ G +    M     G +P       +V +  + G +  A E + K   +P    W SL+
Sbjct:   50 CQQNRLKEALQILHQIDKPSASVYSTLIQSCIKSRL-LQQGKKVHQHIKLSGFVPGLFILNRLLEMYAKCDSLMDSQKLFDEMPERDLCSWNILISGYAKMGLLQEAKSLFDKMPERDNFSWTAMISGYVRHDRPNEALELFRMMKRSDNSKSNKFTVSSALAAAAAVPCLRIGKEIHGYIMRTGLDSDEVVWSALSDMYGKCGSIEEARHIFDKMVDRDIVTWTAMIDRYFQDGRRKEGFDLFADLLRSG-IRPNEFTFSGVLNACANQTSEELGKKVHGYMT--RVGFDPFSFAASALVHMYSKCGNMVSA-ERVFKETPQPDLFSWTSLI 377          

Query:   19 EMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAW---GFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPER-DVVSCTAIISG---YAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVI-----SWNAM-------LVGYSKHGMGKEV----VKLFKLMKEENKVRPDS 945
            E  F G   +LN C N+ +   G++VH +MT+  + P     + L+  Y+ C  +  A+RV  E P  ++ SWT++I+ Y++ G   EA+  F  +++SGT+P+  TF  VL++CA       G D    I      T    H    + ++D+ A++G+  EA  +   +  + D     +++ G   +  L L + A E   +++ E   + YVT A++                                      Y+  G  S   +I  +M +R V+     SW A+       LVG   H   KE+     KL K MKEE  V PD+
Sbjct:  304 EFTFSG---VLNACANQTSEELGKKVHGYMTRVGFDPFSFAASALVHMYSKCGNMVSAERVFKETPQPDLFSWTSLIAGYAQNGQPDEAIRYFELLVKSGTQPDHITFVGVLSACAHAGLVDKGLDYFHSIKEQYGLTHTADHY---ACIIDLLARSGQFDEAENIISKMSMKPDKFLWASLLGGCRIHGNLKLAQRAAEALFEIEPEN-PATYVTLANI--------------------------------------YATAGMWSEVAKIRKTMDDRGVVKKPGLSWIAIKRDVHVFLVGDDSHPKSKEINEFLGKLSKRMKEEGFV-PDT 589          

Query:   40 YTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAG-GAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +TLL  C +     EG+ +HA +  + +   + ++  L+  Y  C  L  A+++ DEM  R+VV+WTA+I+ YS+     +AL L  +MLR G +PN+FT A++L + +G G+     GRQ+H L ++  ++S+++V  ++LDMYA+   + EA+ +F+ +  ++ VS  A+I+GYA+ G  ++A  LF  + RE +   + TY+SVL A + + +L+ G+ VH  +++        + N+L+DMY+K G++  ++++FD + +R V+SWN+ML GYS+HG+GK  ++ F+ M    ++ P+ +TFL VL+ CSH G+ D G  YF  M   +   EP++ HY  +VDLLGRAG ++ A +FI +M  +PTAA+WG+LLGACR+H N+E+G +    + +++    G +V+L N+YA  GRW     VR++M E  V KEP  SW+E++  +H F A D +HP+R                 GYVPD   VL  +D++++E  L  HSEK+ALAF L+ TP G  +R+ KN+RIC DCH+  K VSK+  RE+ +RD NRFHH   G CSC DYW
Sbjct:   19 HTLLKRCTHLNKLNEGKIIHALLLNSRFRDDLVMQNTLLNLYAKCGDLVYARKLFDEMSSRDVVTWTALITGYSQHDRPQDALLLLPEMLRIGLKPNQFTLASLLKAASGVGSTDVLQGRQLHGLCLRYGYDSNVYVSCAILDMYARCHHLEEAQLIFDVMVSKNEVSWNALIAGYARKGQGDKAFCLFSNMLRENVKPTHFTYSSVLCACASMGSLEQGKWVHALMIKWGEKLVAFVGNTLLDMYAKSGSIEDAKKVFDRLAKRDVVSWNSMLTGYSQHGLGKVALQRFEEML-RTRIAPNDITFLCVLTACSHAGLLDEGRHYFDMMK--KYNVEPQISHYVTMVDLLGRAGHLDRAIQFISEMPIKPTAAVWGALLGACRMHKNMELGGYAAECIFELDSHYPGTHVLLYNIYALAGRWNDAAKVRKMMKESGVKKEPACSWVEMENEVHVFVADDDAHPQRREIHNMWEQISDKIKEIGYVPDSSHVLLCMDQQEREAKLQYHSEKLALAFALLNTPPGSTIRIKKNIRICGDCHSAFKFVSKLVEREIIVRDTNRFHHFCDGACSCEDYW 590          

Query:   88 QRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            ++VHA +T T  +  + +  +L+      + L  A  + ++M  R+ VSW+ MI  + K G        F +++R+G++P+ F+   V+ +C     G  +GR IHS ++K       FV S+L+DMYAK G I  A+ +F+ +P++D+V+ T +I+GYA+ G   E+  LF Q++R+G   + V   +++ A + L A++  R VH++V  R     V L  ++IDMY+KCG++  SR IFD M ++ VISW+AM+  Y  HG G+E ++LF +M     + P+ +TF+++L  CSH G+ D GL+ F  M+    G  P+++HY C+VDLLGRAGR+++A   I+ M  E    IW + LGACR+H  V++ E     LL ++ +N G+Y++LSN+YA+ GRW+ V  +R LM ++ + K PG +WIE+D I++ F A D SH R            +    AGYVPD   VL+DVDEE K  +L  HSEK+A+AFGLIATP+G P+R+ KNLR+C DCH+F KLVS I  R++ +RD NRFHH   G CSCGDYW
Sbjct:   20 KQVHAQVTTTGIIHDLIVANKLLYMCAKHKDLVTAHLLFNKMEERDPVSWSVMIGGFVKNGDYERCFQTFRELIRAGSKPDNFSLPFVIKACRD-TMGLIMGRLIHSTVLKNGLHLDNFVCSTLVDMYAKCGMIDNAKQLFDRMPKKDLVTRTVMIAGYAECGKPNESWVLFDQMRRDGFVPDKVAMVTIVNACAKLGAMNKARLVHDYVCARRYSLDVELGTAMIDMYAKCGSIDSSREIFDRMEQKNVISWSAMIGAYGYHGQGREALELFHMMLNSG-IIPNRITFISLLYACSHAGLVDDGLQLFSLMSV-SYGVRPDVKHYTCMVDLLGRAGRLDQALRLIENMEVEKDEGIWCAFLGACRIHRQVDLAEKAAKLLLSLQTQNPGHYILLSNIYANAGRWKDVAKIRNLMAKRRLKKIPGYTWIEVDNIIYRFGAGDNSHLRSKEIYEMLKSLSQKLESAGYVPDTNSVLHDVDEEVKLGILHAHSEKLAIAFGLIATPDGTPIRITKNLRVCGDCHSFCKLVSAITQRDIIVRDANRFHHFKEGICSCGDYW 574          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLI-IKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLP-ERDVVSCTAIISG---YAQLGLDEEALELFRQLQREGMTSNYVTYASV 657
            T++N C    A  + + VH ++    Y   + L T +I  Y  C  ++ ++ + D M  +NV+SW+AMI AY   G   EAL LF  ML SG  PN  TF ++L +C+  A   D G Q+ SL+ +       +   + ++D+  +AGR+ +A  + E +  E+D     A +     + Q+ L E+A +L   LQ +    +Y+  +++
Sbjct:  207 TIVNACAKLGAMNKARLVHDYVCARRYSLDVELGTAMIDMYAKCGSIDSSREIFDRMEQKNVISWSAMIGAYGYHGQGREALELFHMMLNSGIIPNRITFISLLYACS-HAGLVDDGLQLFSLMSVSYGVRPDVKHYTCMVDLLGRAGRLDQALRLIENMEVEKDEGIWCAFLGACRIHRQVDLAEKAAKLLLSLQTQN-PGHYILLSNI 414          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRS-GTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M VQGL      + +L   C N     EG+++H H TK  +    + +  L+  Y+NC CL  A++V D+M  ++VVSW  MI  +++    +EA+ LF +M++S   +PNE T   VLT+CA  A    + ++IH  I +  F  H+ + + L+D+Y K G +  AR +F+   E+++ S   +I+G+ +    EEAL LFR++Q +G+  + VT AS+L A + L AL+LG+ +H ++ ++ +   V L  +L+DMY+KCG++  + ++F  MPE+ V++W A+++G +  G  +  ++ F  M  +  V+PD++TF+ VL+ CSH G  D G+ +F  M++   G +P +EHYG +VD+LGRAGR+ EA E IK M   P   + G LLGACR+H N+E  E    +LL+I+P ++G YV+LSN+Y S  +WE  +  RELM E+ + K PG S IE+  ++H F   D SH +                 AGYVPD   VL+D+ EE+KE  L  HSEK+A+AFGL++T  G P+RV+KNLRIC DCH+  KL+SK+Y RE+ +RD+NRFHH   GTCSC  +W
Sbjct:  136 MMVQGLIPDRYTFPSLFKSCRNSS---EGKQIHCHSTKLGFASDTYAQNTLMNMYSNCGCLVSARKVFDKMEDKSVVSWATMIGVHAQWDQPNEAVRLFDRMMKSENVKPNEVTLVNVLTACAR-ARDLAMVKRIHEYIDEHGFGRHVVLNTVLMDVYCKCGCVQLARDLFDKAQEKNLFSWNIMINGHVEDSNYEEALLLFREMQTKGIKGDKVTMASLLLACTHLGALELGKWLHAYIKKQRIDVDVALGTALVDMYAKCGSIETAIQVFHEMPEKDVMTWTALILGLAMCGQAENALQYFDEMHIKG-VKPDAITFVGVLAACSHAGFVDEGISHFNSMSD-TYGIQPTIEHYGGLVDILGRAGRIAEAEELIKSMPMAPDQFVLGGLLGACRIHGNLEAAERTAKQLLEIDPYHSGTYVLLSNIYKSSKKWEEAKRTRELMAERGMRKPPGCSQIEVHGVVHEFVKGDSSHRQSSEINEMLEDMISKLKNAGYVPDKSEVLFDMAEEEKETELSLHSEKLAIAFGLLSTSVGTPIRVVKNLRICSDCHSATKLISKLYNREIIVRDRNRFHHFKDGTCSCRGFW 717          

Query:   49 LNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYN--NCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELF-RQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL 1173
            + +C N    ++   +HA M +T         ++++ F +  +   L  A+ V  ++P     +  ++I   + +    EAL  + +M+  G  P+ +TF ++  SC   +     G+QIH    K  F S  +  ++L++MY+  G +  AR VF+ + ++ VVS   +I  +AQ     EA+ LF R ++ E +  N VT  +VLTA +    L + +++H ++       +VVL   L+D+Y KCG +  +R +FD   E+ + SWN M+ G+ +    +E + LF+ M+ +  ++ D VT  ++L  C+H G  + G ++ +   + +   + ++     +VD+  + G +E A +   +M  E     W +L+
Sbjct:   52 IEKCSNMSQLKQ---IHAQMLRTGLFFDPFTASKIVAFCSLQDSGSLQYARLVFSQIPNPTSYTCNSIIRGCTDKNLHQEALLFYQEMMVQGLIPDRYTFPSLFKSCRNSS----EGKQIHCHSTKLGFASDTYAQNTLMNMYSNCGCLVSARKVFDKMEDKSVVSWATMIGVHAQWDQPNEAVRLFDRMMKSENVKPNEVTLVNVLTACARARDLAMVKRIHEYIDEHGFGRHVVLNTVLMDVYCKCGCVQLARDLFDKAQEKNLFSWNIMINGHVEDSNYEEALLLFREMQTKG-IKGDKVTMASLLLACTHLGALELG-KWLHAYIKKQR-IDVDVALGTALVDMYAKCGSIETAIQVFHEMP-EKDVMTWTALI 418          

Query:   16 LEMKFEGY----YTL---LNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCEC---LNDAQRVLDEMPVRNVVSWTAMISAYSKRG-CASEALNLFLQMLRSGTEPNEFTFATVLTSCAG--GAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            L+M   GY    +TL   ++ C        G++ H  + K+     + +   L+  Y  C     ++DA++V D MPV NV+SWTA+I+ Y + G C  EA+ LFL+M++   +PN FTF++VL +CA     W   LG Q+++L++K +  S   VG+SL+ MY++ G +  AR  F+ L E+++VS   I++ YA+    EEA ELF +++  G   N  T+AS+L+  S + A+  G Q+H+ +L+    S + + N+LI MYS+CGN+  + ++F+ M +  VISW +M+ G++KHG     ++ F  M E   V P+ VT++AVLS CSH G+   GL++F  M + E+G  P +EHY CVVDLLGR+G +EEA E +  M F+  A +  + LGACRVH N+++G+     +L+ +P +   Y++LSNL+AS G+WE V  +R+ M E+ + KE G SWIE++  +H F+  D SHP+                  GY+P    VL+DV+EEQKE+ L  HSEK+A+A+G I+T    P+RV KNLR+C DCH   K  S +  +E+ LRD NRFHH   GTCSC DYW
Sbjct:  342 LDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDIW---LGEQVYALVVKMRLASINCVGNSLISMYSRCGNMENARKAFDVLFEKNLVSYNTIVNAYAKSLNSEEAFELFNEIEGAGTGVNAFTFASLLSGASSIGAIGKGEQIHSRILKSGFKSNLHICNALISMYSRCGNIEAAFQVFNEMGDGNVISWTSMITGFAKHGFATRALETFHKMLEAG-VSPNEVTYIAVLSACSHVGLISEGLKHFKSM-KVEHGIVPRMEHYACVVDLLGRSGHLEEAMELVNSMPFKADALVLRTFLGACRVHGNMDLGKHAAEIILEQDPHDPAAYILLSNLHASAGQWEEVAEIRKKMKERNLTKEAGCSWIEVENKVHKFYVGDTSHPQAQEIYDELDQLALKIKELGYIPSTDFVLHDVEEEQKEQYLFQHSEKIAVAYGFISTSTSRPIRVFKNLRVCGDCHTAFKYFSIVRRKEIVLRDANRFHHFKDGTCSCNDYW 931          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMP-VRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTK-FESHIFVGSSLLDMYAKA-GRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKC---GNLSYSRRIFDSMPERTVISWNAMLVGY-SKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGL-EYFYEMAEGENGTEPELEHYGCV----VDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVE 1203
            M++QG       Y  LL  C+    ++ G  VH  +T++       +   LI  Y+ C     A  + + M   R++VSW+A+IS Y+    A EA++ F  ML  G  PNE+ F  V  +C+       LG+ I   ++KT  FES + VG +L+DM+ K  G +  A  VF+ +P+R+VV+ T +I+ + QLG   +A++LF  +   G   +  T + V++A + +  L LGRQ H  V++  L   V +  SL+DMY+KC   G++  +R++FD MP   V+SW A++ GY    G  +E ++LF L   + +V+P+  TF +VL  C++  + D  L E  Y +       +  L    CV    + +  R G +E A +    + FE     + +++ A     N E
Sbjct:  139 MSLQGTHPDLITYSLLLKSCIRSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKE-NISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELF-LEMVQGQVKPNHFTFSSVLKACAN--LSDIWLGEQVYALV-----VKMRLASINCVGNSLISMYSRCGNMENARKAFDVL-FEKNLVSYNTIVNAYAKSLNSE 541          

Query:  244 MISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECL-PERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRR-ELPSYVVLQNSLIDMYSK-CGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGC-VVDLLGRA---GRVEEAFEFIKKM-----------------------------------RFEPTAAIWGSLLGACRVHSNVEIGE-----FVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVI 1350
            M  A  ++    +A++   QM   GT P+  T++ +L SC   +  + LG  +H  + ++  E    + +SL+ +Y+K G   +A  +FE +  +RD+VS +A+IS YA      EA+  F  +   G   N   +  V  A S    + LG+ +   +L+     S V +  +LIDM+ K  G+L  + ++FD MP+R V++W  M+  + + G  ++ V LF  M     V PD  T   V+S C+  G+   G ++   +   ++G + ++   GC +VD+  +    G V++A +   +M                                   + +P    + S+L AC   S++ +GE      V  RL  I     GN +I  ++Y+  G  E  R   +++ EK ++
Sbjct:  119 MEMAGQRKRLNKKAISTLDQMSLQGTHPDLITYSLLLKSCI-RSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYV-PDRFTLSGVVSACAEMGLLSLGRQFHCLVM--KSGLDLDV-CVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDIWLGEQVYALVVKMRLASI--NCVGNSLI--SMYSRCGNMENARKAFDVLFEKNLV 525          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMP--VRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSG-LAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGVA------------GYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M + G+++    +  ++  C N +     +++H  + K+ +    ++RT L++ Y+ C  +++A ++   M   VRNVVSWTAMIS Y + G A +A+NLF QM R G +PN+FT++T+LT+  G +       ++H+  IK  +     VG++LLD Y K G + EA  VF+ + E+D+V+ +A+I GYAQ+G  E A+ +F Q+ +E +  N  T++ ++ A +   A ++ G+Q+H   ++    + + + ++L+ MYSK G++  +  +F    ER ++SWN+++ GY++HG G++ +++F+ M+ +N +  D VTF+ V+S C+H G+ + G  YF  M + ++  EP +EHY C+VDL GRAG + +A E I +M F  +A +W +LL A  +H N+E+G+    +L+ ++P+N  +YV+L+N+YASVG W+    VR+LM EK V K  G SWIE+    +TF A D SHP  ++  A            GY PD   V  DVDEE KE +L  HSE++A+AFGLI TP G P++++KNLR+C DCH+  KL+S + GR++ +RD NRFHH  GG CSCGDYW
Sbjct:  150 MRLAGVKLTKMVFAPVIKLCGNIKELGFSRQLHCQVLKSGFEYDKNIRTTLMLAYSKCGEMDNAFKIFSVMSDEVRNVVSWTAMISGYLQNGMAEQAVNLFCQMSREGIKPNDFTYSTILTAQPGVS-----PFEMHAQAIKRNYVKSPSVGTALLDAYVKRGNVDEASKVFQRIEEKDIVAWSAMICGYAQIGDTEGAVRIFVQMAKEKIKPNEYTFSGIINACAAPTAGVEQGKQLHAWSIKSRFNNALCVSSALLTMYSKRGDIESAFEVFKRQRERDLVSWNSIISGYAQHGYGRKALEVFEEMQRQN-LEMDGVTFIGVISACTHTGLANEGQRYFDIMVK-DHHIEPRMEHYSCMVDLYGRAGMLVKAMEIINEMPFPASANVWRTLLAASCIHRNLEVGKLAADKLISLQPQNPASYVLLTNMYASVGNWKERAKVRKLMEEKKVKKVAGYSWIEVKNKTYTFLAGDVSHPLSNQIYAKLEELSCQLKGAGYQPDTSYVFQDVDEEHKEAILSQHSERLAIAFGLIGTPPGTPLQIVKNLRVCGDCHSVIKLISILEGRDIVVRDSNRFHHFKGGLCSCGDYW 732          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPE--RDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCS--HGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVH 1191
            M V+G++     +  ++    +      G +VH  + K  +         LI  Y     + DA+ V D M  RN VSW +M++     G   E L++F  M  +G +  +  FA V+  C G        RQ+H  ++K+ FE    + ++L+  Y+K G +  A  +F  + +  R+VVS TA+ISGY Q G+ E+A+ LF Q+ REG+  N  TY+++LTA  G++  ++    H   ++R       +  +L+D Y K GN+  + ++F  + E+ +++W+AM+ GY++ G  +  V++F  M +E K++P+  TF  +++ C+    G+E     + + +    N     L     ++ +  + G +E AFE  K+ R E     W S++     H
Sbjct:   49 MLVEGIKPNPFTFSAVIGALTDEGMVEAGIQVHTMVIKNGFGVATFASNSLINMYFKSGMIRDARAVFDSMTDRNAVSWNSMVAGLVTNGLHLETLDVFYHMRLAGVKLTKMVFAPVIKLC-GNIKELGFSRQLHCQVLKSGFEYDKNIRTTLMLAYSKCGEMDNAFKIFSVMSDEVRNVVSWTAMISGYLQNGMAEQAVNLFCQMSREGIKPNDFTYSTILTAQPGVSPFEM----HAQAIKRNYVKSPSVGTALLDAYVKRGNVDEASKVFQRIEEKDIVAWSAMICGYAQIGDTEGAVRIFVQMAKE-KIKPNEYTFSGIINACAAPTAGVEQGKQLHAWSIKSRFNNA---LCVSSALLTMYSKRGDIESAFEVFKRQR-ERDLVSWNSIISGYAQH 439          

Query:  163 YNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPE--RTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLS---GCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL 1173
            Y   E + + +R  DEM  RNVVSWT++++ Y++ G   E L LFL+ML  G +PN FTF+ V+ +        + G Q+H+++IK  F    F  +SL++MY K+G I +AR VF+ + +R+ VS  ++++G    GL  E L++F  ++  G+    + +A V+     +  L   RQ+H  VL+        ++ +L+  YSKCG +  + +IF  M +  R V+SW AM+ GY ++GM ++ V LF  M  E  ++P+  T+  +L+   G S   M  + ++  Y +     GT         ++D   + G V+EA +  +++  E     W +++
Sbjct:    2 YLKNENVEEGRRAFDEMGARNVVSWTSLLTGYAQNGLNVETLKLFLRMLVEGIKPNPFTFSAVIGALTDEGM-VEAGIQVHTMVIKNGFGVATFASNSLINMYFKSGMIRDARAVFDSMTDRNAVSWNSMVAGLVTNGLHLETLDVFYHMRLAGVKLTKMVFAPVIKLCGNIKELGFSRQLHCQVLKSGFEYDKNIRTTLMLAYSKCGEMDNAFKIFSVMSDEVRNVVSWTAMISGYLQNGMAEQAVNLFCQMSREG-IKPNDFTYSTILTAQPGVSPFEMHAQAIKRNY-VKSPSVGT--------ALLDAYVKRGNVDEASKVFQRIE-EKDIVAWSAMI 331          

Query:  466 MYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFE 1143
            MY K   + E R  F+ +  R+VVS T++++GYAQ GL+ E L+LF ++  EG+  N  T+++V+ AL+    ++ G QVH  V++          NSLI+MY K G +  +R +FDSM +R  +SWN+M+ G   +G+  E + +F  M+    V+   + F  V+  C  G +++ G          ++G E +      ++    + G ++ AF+    M  E
Sbjct:    1 MYLKNENVEEGRRAFDEMGARNVVSWTSLLTGYAQNGLNVETLKLFLRMLVEGIKPNPFTFSAVIGALTDEGMVEAGIQVHTMVIKNGFGVATFASNSLINMYFKSGMIRDARAVFDSMTDRNAVSWNSMVAGLVTNGLHLETLDVFYHMRLAG-VKLTKMVFAPVIKLC--GNIKELGFSRQLHCQVLKSGFEYDKNIRTTLMLAYSKCGEMDNAFKIFSVMSDE 223          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA  GLEMKF+GYYTLLNEC+NRRAFREGQRVHAHM KTCYLPPMHLRTRLIVFYNNC+ L DA+RVLDEMP RNVVSWTAM+SAYSKRG ASEALNLFLQM RSGTEPNEFTFAT+LTSC G + G DLGRQIHSLII+  FESHIFVGSSLLDMYAKAGRIYEARGVF+CLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGM SNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVL NSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEE+K RPDSVTFLAVLSGCSHGGMEDRGLEYFYEM +GENG EPELEHYGCVVDLLGRAGRVEEAFEFIKKM FEPTAAIWGSLLGACRVHSN++IGEFVGFRLLQIEPENA             GRWE VR VRELM+EKAVIKEPGRSWIELDQILHTFHASDRSHPRR                AGYVPDLGCVLYDVDEEQKEK+LLGHSEK+ALAFGLIAT EGVPVRVIKNLRICVDCHNFAKLVS+IY REVSLRDKNRFHHIVGG CSCGDYW
Sbjct:  453 MAAIGLEMKFDGYYTLLNECINRRAFREGQRVHAHMIKTCYLPPMHLRTRLIVFYNNCDRLGDARRVLDEMPERNVVSWTAMVSAYSKRGYASEALNLFLQMFRSGTEPNEFTFATLLTSCTGAS-GLDLGRQIHSLIIRRNFESHIFVGSSLLDMYAKAGRIYEARGVFDCLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMISNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLLNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEESKARPDSVTFLAVLSGCSHGGMEDRGLEYFYEMEKGENGIEPELEHYGCVVDLLGRAGRVEEAFEFIKKMHFEPTAAIWGSLLGACRVHSNIDIGEFVGFRLLQIEPENA-------------GRWEDVRTVRELMLEKAVIKEPGRSWIELDQILHTFHASDRSHPRREEVSAKVKELSIKLKEAGYVPDLGCVLYDVDEEQKEKILLGHSEKLALAFGLIATAEGVPVRVIKNLRICVDCHNFAKLVSEIYRREVSLRDKNRFHHIVGGICSCGDYW 1025          

Query:  595 ELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEY----------------------------FYEMAEGENGTEPELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFE---PTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSN----LYASVGRWEGVRNVRELMVEKAVI 1350
            E   ++   G+   +  Y ++L       A   G++VH H+++      + L+  LI  Y+ C  L  +RR+ D MPER V+SW AM+  YSK G   E + LF L    +   P+  TF  +L+ C+     D G +                              YE A G     PE +   C   + G A  G  EEA E  ++++ E        + S+L A    + +++G  V   +L+ E     +YV+L N    +Y+  G     R + + M E+ VI
Sbjct:  448 EALLEMAAIGLEMKFDGYYTLLNECINRRAFREGQRVHAHMIKTCYLPPMHLRTRLIVFYNNCDRLGDARRVLDEMPERNVVSWTAMVSAYSKRGYASEALNLF-LQMFRSGTEPNEFTFATLLTSCTGASGLDLGRQIHSLIIRRNFESHIFVGSSLLDMYAKAGRIYE-ARGVFDCLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMISNYVTYASVLTALSGLAALDLGRQVHNHVLRRE---LPSYVVLLNSLIDMYSKCGNLSYSRRIFDSMPERTVI 731          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y  LL+ C      ++ + VH+H+  + +   + +R  ++  Y  C  L+DA+ + ++MP +++V+WTA+IS YS+     +AL LF +MLR G EPN+FT +++L + +G     + GRQ+H+   K   +S+++VG++L+DMYA+ G + E++ VF+ L  ++ VS  A+I+G+A+    E AL LF ++ REG    + TY+SVLTA +   +L+ G+ VH H+++  +     + N+L+DMY+K G++  ++++FD M  R V+SWN+ML GY++HG GKE V+ F+ M     ++P+ +TFL VL+ CSH G+ D G +Y++++ +  N  EP++ HY  +VDLLGR   ++ A +FI++M  EPTAA+WG+LLGACR+H N+E+G +   R  +++P ++G +VILSN+YAS GRW     VR++M E  V KEP  SW++++  +H F A+D +HP+R   +             GYVPD   VL+ VD++++E  L  HSEK+ALAF ++ TP G  +R+ KN+R+C DCH+  K VSK+ GRE+ +RD NRFHH   G+CSCGDYW
Sbjct:  112 YNKLLHRCTQTAQLKQARIVHSHILTSQFKDDLPIRNTILHMYVKCGSLDDARNLFNQMPHKDLVTWTALISGYSQHDRPQDALVLFPEMLRHGLEPNQFTLSSLLKA-SGAVSDDNHGRQLHTYCFKYGLDSNVYVGTALVDMYARCGHMDESQLVFDALDTKNEVSWNALIAGHARKAQGEHALRLFWKMLREGFKPTHFTYSSVLTACASAGSLEQGKWVHAHMIKSVVTLVAFVGNTLLDMYAKSGSIEDAKKVFDRMVRRDVVSWNSMLTGYAQHGFGKETVQRFEEMLRIG-IQPNDITFLCVLTACSHAGLLDEG-QYYFDLMKQYN-IEPQVSHYVTIVDLLGRGNLLDRAEKFIREMPIEPTAAVWGALLGACRMHKNIELGAYAAERSFELDPHDSGPHVILSNIYASAGRWIDAAKVRKMMKEGGVKKEPACSWVDIENAVHMFVANDDAHPQRVEILRMWEMISMKIKEVGYVPDTSHVLFYVDQQEREVKLQYHSEKLALAFAVLNTPPGSTIRIKKNIRVCGDCHSAIKFVSKVEGREIIVRDTNRFHHFRDGSCSCGDYW 682          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCA------GGAWGFDLGRQ 399
            M  +G +     Y ++L  C +  +  +G+ VHAHM K+       +   L+  Y     + DA++V D M  R+VVSW +M++ Y++ G   E +  F +MLR G +PN+ TF  VLT+C+       G + FDL +Q
Sbjct:  302 MLREGFKPTHFTYSSVLTACASAGSLEQGKWVHAHMIKSVVTLVAFVGNTLLDMYAKSGSIEDAKKVFDRMVRRDVVSWNSMLTGYAQHGFGKETVQRFEEMLRIGIQPNDITFLCVLTACSHAGLLDEGQYYFDLMKQ 440          

Query:   49 LNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHP------------RRHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            L  C    A   G+ VH  + K+CY   +++ T L+  Y     + +A++V  EMP  +VV W+ M+S Y++     EAL+LF +M ++   PN+FT+A+ L +CA      D G QIH  + K   +S ++V ++L+ +YAK G+I ++  +F   P R+ VS   +I GYAQLG  E+AL LF  + R  + +  VTY+S L A SGLAAL+ G Q+H+  ++       V+ NSLIDMY+KCGN+  +R +FD + +R  +SWN M+ GYS HG+  E +K+F++M+E N  +P+ +TF+ VLS CS+ G+ D+G  YF  M + +   EP +EHY C+V LLGR+G +++A + I ++ FEP+  +W +LLGAC +H++VE+G      +L+++P++   +V+LSN+YA+  RW+ V  VR+ M  K V KEPG SWIE    +H F   D SHP            +     AG+VP+   +L DV E++KE++L  HSE++ALAFGL+  P G P+R+IKNLRIC+DCH   KL+SKI  R++ +RD NRFHH   G CSCGDYW
Sbjct:  373 LKACAGLEALNGGKSVHGCVIKSCYEGDLYVGTALLDLYTKFGDIEEARQVFQEMPKNDVVPWSLMVSRYAQSDRCEEALDLFCRMRQAFVVPNQFTYASTLQACATMEH-LDFGMQIHCHVTKVGIDSDVYVSNALMGVYAKCGKIDDSMDLFVESPNRNDVSWNTMIVGYAQLGDGEKALMLFSGMIRCQVEATEVTYSSALHASSGLAALESGVQIHSVTVKTIYDKDTVVGNSLIDMYAKCGNIKDARLVFDKLKQRDEVSWNTMISGYSMHGLALEALKVFEMMQETN-CKPNKLTFVGVLSACSNAGLLDQGQAYFDSMVQ-DYDVEPCIEHYTCMVWLLGRSGHLDKAVKLINEIPFEPSIMVWRALLGACVIHNDVELGRTAAKHVLEMDPQDEATHVLLSNIYATAKRWDNVAYVRKNMKRKGVKKEPGLSWIENQGTVHYFAVGDTSHPDMKLINGMLEWLKLRTLKAGHVPNCNAILLDVAEDEKERLLWVHSERLALAFGLVRAPSGSPIRIIKNLRICMDCHATVKLISKIVQRDIIVRDLNRFHHFQDGVCSCGDYW 940          

Query:   19 EMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFE 1119
            E     Y  +L  C+     R    +H  + K      +     L+  Y     L DA  + DEM  RNV+S+  +I  +S  G   +A+ LF  + R G E N+F F T+L       W  +L   +H+ I K    S  FVG++L+D Y+  G +  AR VF+ +  +D+V+ T +++ YA+ G  EEALELF Q++  G   N  T+   L A +GL AL+ G+ VH  V++      + +  +L+D+Y+K G++  +R++F  MP+  V+ W+ M+  Y++    +E + LF  M++   V P+  T+ + L  C+     D G++    +   + G + ++     ++ +  + G+++++ +
Sbjct:  161 EFDSHAYGVVLQHCIRNGDARSAMGLHCEILKKGGCLDLFADNILLNMYVKAGMLVDAANLFDEMSERNVISFVTLIQGFSDYGRFVDAVELFSGLHREGHELNQFVFTTILKLLVRTGWA-ELVWTVHACIHKLAHGSSAFVGTALIDAYSVCGYVNVARDVFDEVVCKDMVAWTGMVACYAENGCSEEALELFSQMRVIGFRPNNYTFTGALKACAGLEALNGGKSVHGCVIKSCYEGDLYVGTALLDLYTKFGDIEEARQVFQEMPKNDVVPWSLMVSRYAQSDRCEEALDLFCRMRQAFVV-PNQFTYASTLQACATMEHLDFGMQIHCHVT--KVGIDSDVYVSNALMGVYAKCGKIDDSMD 523          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLR-RELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMP-ERTVISWNAML 858
            Y + L  C        G ++H H+TK      +++   L+  Y  C  ++D+  +  E P RN VSW  MI  Y++ G   +AL LF  M+R   E  E T+++ L + +G A   + G QIHS+ +KT ++    VG+SL+DMYAK G I +AR VF+ L +RD VS   +ISGY+  GL  EAL++F  +Q      N +T+  VL+A S    LD G+   + +++  ++   +     ++ +  + G+L  + ++ + +P E +++ W A+L
Sbjct:  470 YASTLQACATMEHLDFGMQIHCHVTKVGIDSDVYVSNALMGVYAKCGKIDDSMDLFVESPNRNDVSWNTMIVGYAQLGDGEKALMLFSGMIRCQVEATEVTYSSALHASSGLA-ALESGVQIHSVTVKTIYDKDTVVGNSLIDMYAKCGNIKDARLVFDKLKQRDEVSWNTMISGYSMHGLALEALKVFEMMQETNCKPNKLTFVGVLSACSNAGLLDQGQAYFDSMVQDYDVEPCIEHYTCMVWLLGRSGHLDKAVKLINEIPFEPSIMVWRALL 744          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLR--------------------------------SGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y TLL  C+++RA  +G+ VHAH   + ++P M +  RLI  Y  C  + DAQ V DEMP R++ SW  MIS Y+K G  +EA  LF +M +                                  ++ N+FT ++VL + A       +G++IH  I++T  +S   V S+L DMY K G I EAR +F+ +  RD+V+ TA+I  Y + G  EE   LF +L + G+  N  T+A VL A +  AA +LG+QVH ++ R          ++L+ MYSKCGN+  + ++F+ MP   V+SW +++ G++++G   E ++LFKL+ +    +PD +TF+ VLS C+H G+ D+GLEYF+ + + ++G     +HY CVVDLL RAGR EEA   I +M  +P   +W SL+G CR+H N+ + +     L +IEPEN   Y+ L+N+YA+ G W  V  VR++M ++ +IK+PG SWIE+ + +H F   D SHPR            +     GYVPD   VL+DV+EEQKE+ L  H EK+A+AFG+I+TP G P++V KNLR CVDCH   K VSKI  R++ +RD NRFH   GG CSC DYW
Sbjct:   89 YSTLLQLCLHQRALAQGKLVHAHTRASGFVPGMFICNRLIXMYAKCGSIVDAQMVFDEMPERDLCSWNTMISGYAKVGQLAEARKLFDEMPQRDNFSWTAVISGYVRHDXPKDALWLYRMMQRSENSKSNKFTVSSVLAASAA-IQSLRMGKEIHGYIMRTGLDSDEVVWSALSDMYGKCGSIEEARRIFDKMVNRDIVTWTAMIDRYFEDGXKEEGFSLFSELMKSGIRPNEFTFAGVLNACAQHAAENLGKQVHGYMTRIGFDPLSFAASALVHMYSKCGNIENANKVFNEMPCPDVVSWTSLIAGHAQNGQPNEALQLFKLLLDSG-TKPDHITFVGVLSACTHAGLVDKGLEYFHSI-KAKHGLTHTADHYSCVVDLLARAGRFEEAKNIINEMPMKPDKYLWASLIGGCRIHGNLTLAKRAADALFEIEPENPTTYITLANIYATAGMWGEVTEVRKMMDKRGLIKKPGLSWIEIKREVHXFLVGDTSHPRYDEIXHYLHELSKRMKEEGYVPDTNFVLHDVEEEQKEQNLSYHXEKLAVAFGIISTPPGTPIKVFKNLRTCVDCHTAIKFVSKIANRKIIVRDSNRFHCFEGGICSCRDYW 692          

Query:   19 EMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQ-IHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPER-DVVSCTAIISG---YAQLGLDEEALELFRQLQREGMTSNYVTYASV 657
            E  F G   +LN C    A   G++VH +MT+  + P     + L+  Y+ C  + +A +V +EMP  +VVSWT++I+ +++ G  +EAL LF  +L SGT+P+  TF  VL++C   A   D G +  HS+  K          S ++D+ A+AGR  EA+ +   +P + D     ++I G   +  L L + A +   +++ E  T+ Y+T A++
Sbjct:  320 EFTFAG---VLNACAQHAAENLGKQVHGYMTRIGFDPLSFAASALVHMYSKCGNIENANKVFNEMPCPDVVSWTSLIAGHAQNGQPNEALQLFKLLLDSGTKPDHITFVGVLSACT-HAGLVDKGLEYFHSIKAKHGLTHTADHYSCVVDLLARAGRFEEAKNIINEMPMKPDKYLWASLIGGCRIHGNLTLAKRAADALFEIEPENPTT-YITLANI 532          

Query:  586 EALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGEN 1038
            EA++L   + +   +     Y+++L       AL  G+ VH H         + + N LI MY+KCG++  ++ +FD MPER + SWN M+ GY+K G   E  KLF  M +      D+ ++ AV+SG          L  +  M   EN
Sbjct:   73 EAVQLLHHIDKPSAS----IYSTLLQLCLHQRALAQGKLVHAHTRASGFVPGMFICNRLIXMYAKCGSIVDAQMVFDEMPERDLCSWNTMISGYAKVGQLAEARKLFDEMPQR-----DNFSWTAVISGYVRHDXPKDALWLYRMMQRSEN 214          

Query:  547 AIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQ-NSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLE-YFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKM 1134
            +I S   QL L + AL   + +      S +V    +   L  + A   G  V   ++  E+P   +   N++I  Y+K G L+ +R++FD MP+R   SW A++ GY +H   K+ + L+++M+     + +  T  +VL+  +       G E + Y M  G +  E     +  + D+ G+ G +EEA     KM
Sbjct:   87 SIYSTLLQLCLHQRALAQGKLVHAHTRASGFVPGMFICNRLIXMYA-KCGSIVDAQMVFDEMPERDLCSWNTMISGYAKVGQLAEARKLFDEMPQRDNFSWTAVISGYVRHDXPKDALWLYRMMQRSENSKSNKFTVSSVLAASAAIQSLRMGKEIHGYIMRTGLDSDEVV---WSALSDMYGKCGSIEEARRIFDKM 280          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            Y  L+  C+ RRA ++G+ VH H+    Y P   L    I  Y     L +AQ + DEMP RNVVSWT MISAYS      +AL   + MLR G  PN FT+++VL +C G        +Q+H  I     ES +FV S+L+D+Y+K G ++ A G F  +   D+V   +II  +AQ    +EA  LF++++R G  +   T  SVL A + LA L+LGRQVH H ++      ++L N+L+DMY KCG+L  +   F  M ++ VISW+ M+ G +++G  +E ++LF+ MK  + V+P+ +T L VL  CSH G+ + G  YF  M +   G +P  EHYGCV+DLLGRAG+++EA   I++M  EP A  W +LLGACRVH NV++  +   ++L+ +P++AG Y++LSN+YA+  RWE V  VR+ M  + VIKEPG SWIE+++ +H F   D SHP+                  GY+PD   VL D++ EQ+E  LL HSEK+A+ FGL++  +G  VR+ KNLRIC DCH FAKLV+ I  R + +RD  R+HH   G CSCGDYW
Sbjct:   88 YSELVKCCLARRAVQQGKLVHKHVFSNGYQPKTFLINVFINMYVKFALLEEAQELFDEMPERNVVSWTTMISAYSNXXXNXKALEXLVLMLREGVSPNSFTYSSVLRACXG----LXNLKQLHCCIFXXGLESDVFVRSALIDVYSKLGELHNALGXFNEMVSGDLVVWNSIIGAFAQNSDGDEAXNLFKRMKRAGFXAEEATLTSVLRACTVLALLELGRQVHVHAVK--YGQDLILNNALLDMYCKCGSLEDANSAFTRMEKKDVISWSTMIAGLAQNGFSQEALRLFEQMKX-SXVKPNYITLLGVLFACSHAGLLEDGWYYFQNMKQ-LFGIDPGREHYGCVIDLLGRAGKLDEAARLIQEMEGEPDAVTWRTLLGACRVHRNVDLAAYAAKQILKTDPDDAGTYILLSNIYANSQRWEDVTEVRKSMKARGVIKEPGCSWIEVNKQIHAFILGDDSHPQIDEINRQLSLLIDRLMAVGYIPDTNFVLQDLEGEQREVSLLSHSEKLAIVFGLMSLSKGKTVRIRKNLRICGDCHVFAKLVAXIEERSIVIRDPIRYHHFQDGVCSCGDYW 654          

Query:  589 ALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCS--------HGGMEDRGLE-----------YFYEMAEGENG-------TEPELEHYGCVVDLLGRAGRVEEAFEFIKKMR---FEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSN----LYASVGRWEGVRNVRELMVEKAVI 1350
            A+     +QR G+ ++ V Y+ ++       A+  G+ VH HV          L N  I+MY K   L  ++ +FD MPER V+SW  M+  YS      + ++   LM  E  V P+S T+ +VL  C         H  +   GLE            + ++ E  N           +L  +  ++    +    +EA    K+M+   F    A   S+L AC V + +E+G     R + +     G  +IL+N    +Y   G  E   +    M +K VI
Sbjct:   69 AMIAMEAMQRRGLWADSVVYSELVKCCLARRAVQQGKLVHKHVFSNGYQPKTFLINVFINMYVKFALLEEAQELFDEMPERNVVSWTTMISAYSNXXXNXKALEXLVLMLREG-VSPNSFTYSSVLRACXGLXNLKQLHCCIFXXGLESDVFVRSALIDVYSKLGELHNALGXFNEMVSGDLVVWNSIIGAFAQNSDGDEAXNLFKRMKRAGFXAEEATLTSVLRACTVLALLELG-----RQVHVHAVKYGQDLILNNALLDMYCKCGSLEDANSAFTRMEKKDVI 349          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKT--------------------------CYLPPMHLR-----TRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRR-ELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHP------------RRHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M + G+E     +  LL  C    A  EG++VH H+ K                                 HLR     T LI  Y +  C++DA+ + DE+PVR+VVSW AMIS Y++R    EAL LF +M ++   PNE T  TVL++CA      +LG+ + S I      S++ + S+L+DMY+K G +  ARG+F+ L +RDV+S   +I GY      +EAL  FR + R     N VT+ ++L A + L ALDLG+ +H ++ +  +  +   L  SLIDMY KCGN+  ++++F+ M  +++ SWNAM+ G + HG     ++LF  M++E    PD++TF+ VLS C+HGG+ D G +YF  M    +   PEL HYGC++D+LGRAG  +EA   +K M  +P  A+WGSLLGACR+H  VE+GE V   L ++EPENAG YV+LSN+YA  GRW+ +  +R  + +  + K PG + I ++ ++H F  SD+SHP             R    AG+VPD   VLYD+ EE KE  L  HSEK+A+AFGLI+T  G  +R++KNLR+C +CH+  KL+SKI+ RE+  RD NRFHH   G+CSC D W
Sbjct:  121 MILSGVEPNSYTFPFLLKSCTKTAATHEGKQVHGHVVKLGLESDAFVHTSLINMYAQNGELVSARXVFDKSHLRDAVSFTALISGYVSRGCMDDARVLFDEIPVRDVVSWNAMISGYAQRDRFEEALALFGEMRKANVSPNESTMVTVLSACAQSG-SLELGKWVASWIEDHGLGSNLRLVSALIDMYSKCGALDIARGLFDGLQQRDVISWNVMIGGYTHKSHYKEALMQFRLMLRSNTQPNDVTFLAILPACAHLGALDLGKWIHAYIDKNFQKFTNTSLWTSLIDMYXKCGNIEAAKQVFNGMETKSLASWNAMISGLAMHGDAHAALELFSKMEDEG-FNPDAITFVGVLSACNHGGLVDLGRQYFSSMTTDYH-IXPELHHYGCMIDILGRAGLFDEAGALMKSMEMKPDGAVWGSLLGACRLHRRVELGESVAKHLFEVEPENAGAYVLLSNIYAGAGRWDDMARIRTRLNDLGIKKVPGSTSIXVNSVVHEFLVSDKSHPLSKEIYEMLEEIDRLLDKAGFVPDTSEVLYDMGEEWKEVALSHHSEKLAIAFGLISTKPGTTIRIVKNLRVCGNCHSATKLISKIFNREIIARDGNRFHHFRDGSCSCNDNW 736          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVF--YNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAI-------------------------------ISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSN 1197
            TLL++C   ++ +  ++VH H+ KT         ++LI F   +    L+ A  V + +   N + W  +I  YS      EA+  +++M+ SG EPN +TF  +L SC   A   + G+Q+H  ++K   ES  FV +SL++MYA+ G +  AR VF+    RD VS TA+                               ISGYAQ    EEAL LF ++++  ++ N  T  +VL+A +   +L+LG+ V + +    L S + L ++LIDMYSKCG L  +R +FD + +R VISWN M+ GY+     KE +  F+LM   N  +P+ VTFLA+L  C+H G  D G ++ +   +           +  ++D+  + G +E A +    M  +  A+ W +++    +H +
Sbjct:   35 TLLSKC---KSIQNLKQVHTHIVKTGLHNXHFALSKLIEFCAVSPFGDLSYALSVFESIENPNQIVWNTIIRGYSLSSRPLEAVEFYVRMILSGVEPNSYTFPFLLKSCTKTAATHE-GKQVHGHVVKLGLESDAFVHTSLINMYAQNGELVSARXVFDKSHLRDAVSFTALISGYVSRGCMDDARVLFDEIPVRDVVSWNAMISGYAQRDRFEEALALFGEMRKANVSPNESTMVTVLSACAQSGSLELGKWVASWIEDHGLGSNLRLVSALIDMYSKCGALDIARGLFDGLQQRDVISWNVMIGGYTHKSHYKEALMQFRLMLRSN-TQPNDVTFLAILPACAHLGALDLG-KWIHAYIDKNFQKFTNTSLWTSLIDMYXKCGNIEAAKQVFNGMETKSLAS-WNAMISGLAMHGD 445          

Query:   79 REGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            REG+++H H TK  +    +++   +  Y NC CL  A++V D+M  ++VVSW  MI AY+K     EAL LF +M     +PNE T   VLT+CA  A   D+ +++H  I    F SH+ + ++LLD+Y K G +  AR +F+ + E+++ S   +I+G+ +    +EA  LFR++Q +G   + VT  S+L A S L AL+LG+ +H ++ + ++   V L  +L+DMY+KCG++  +  +F  +PE+ V++W A++ G++  G G++ ++ F  M++   V+PD++TF+ VL+ CSH G+ D G+ +F  M+E   G +P +EHYG +VD+LGRAGR+ EA E I+KM+  P   + G LLGACRVH N+E  E V  +LL+++P + G YV+LSNLY+S+ +W+  + +R LM E+ V K PG S IE+D I+H F   D SHP+                 AGYVP+   VL D+DEE+KE  L  HSEK+A+AFGLI+T     +RV+KNLR+C DCH   KL+SK+Y RE+ +RD+NRFH    G+CSC D+W
Sbjct:  161 REGKQLHCHSTKFGFASDSYIQNTXMNMYANCGCLVSARKVFDKMTEKSVVSWATMIDAYAKWDXPVEALKLFXRMESENVDPNEVTLVNVLTACAR-ARDLDMAKRVHRYIDDYGFGSHLKLNTALLDVYCKCGCVSLARXLFDTMREKNLFSWNIMINGHVEDSNYDEAFLLFREMQLKGEKGDQVTMVSLLLACSHLGALELGKWLHAYIEKEKIKVDVALGTTLVDMYAKCGSIDDALEVFRKLPEKDVMTWTALISGFAMCGQGRKALEHFHEMQKSG-VKPDAITFVGVLAACSHAGLVDEGISHFNSMSE-VYGIQPSIEHYGGMVDILGRAGRIAEAEELIRKMQXPPDRFVLGGLLGACRVHGNLEAAERVARQLLELDPNDDGAYVLLSNLYSSMKKWDEAKRIRALMAERNVKKAPGCSLIEVDGIVHEFVKGDSSHPQTTXIYEMLEDMISRLKKAGYVPEXSEVLLDIDEEEKETALSLHSEKLAIAFGLISTKPRTTIRVVKNLRVCSDCHTATKLISKVYNREIIVRDRNRFHRFRDGSCSCKDFW 718          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVF--YNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDL--GRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL 1173
            TLL++C       E +++HA + +T         ++++ F        L  A+ VL+++P     +  ++I  Y+ +    +A+  + +M+  G  P+ FTF ++  SC       DL  G+Q+H    K  F S  ++ ++ ++MYA  G +  AR VF+ + E+ VVS   +I  YA+     EAL+LF +++ E +  N VT  +VLTA +    LD+ ++VH ++      S++ L  +L+D+Y KCG +S +R +FD+M E+ + SWN M+ G+ +     E   LF+ M+ + + + D VT +++L  CSH G  + G ++ +   E E   + ++     +VD+  + G +++A E  +K+  E     W +L+
Sbjct:   52 TLLDKC---STMSELKQIHAQLLRTGLFFDAFTASKVVAFSALEGSGSLRYARLVLNQIPNPTTYTCNSVIRGYTNKDLNRDAILFYQEMILQGWVPDSFTFPSLFKSCG------DLREGKQLHCHSTKFGFASDSYIQNTXMNMYANCGCLVSARKVFDKMTEKSVVSWATMIDAYAKWDXPVEALKLFXRMESENVDPNEVTLVNVLTACARARDLDMAKRVHRYIDDYGFGSHLKLNTALLDVYCKCGCVSLARXLFDTMREKNLFSWNIMINGHVEDSNYDEAFLLFREMQLKGE-KGDQVTMVSLLLACSHLGALELG-KWLHAYIEKEK-IKVDVALGTTLVDMYAKCGSIDDALEVFRKLP-EKDVMTWTALI 419          

Query:   46 LLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLR-RELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSM---PERTVI 840
            +L  C   R     +RVH ++    +   + L T L+  Y  C C++ A+ + D M  +N+ SW  MI+ + +     EA  LF +M   G + ++ T  ++L +C+      +LG+ +H+ I K K +  + +G++L+DMYAK G I +A  VF  LPE+DV++ TA+ISG+A  G   +ALE F ++Q+ G+  + +T+  VL A S    +D G    N +     +   +     ++D+  + G ++ +  +   M   P+R V+
Sbjct:  251 VLTACARARDLDMAKRVHRYIDDYGFGSHLKLNTALLDVYCKCGCVSLARXLFDTMREKNLFSWNIMINGHVEDSNYDEAFLLFREMQLKGEKGDQVTMVSLLLACS-HLGALELGKWLHAYIEKEKIKVDVALGTTLVDMYAKCGSIDDALEVFRKLPEKDVMTWTALISGFAMCGQGRKALEHFHEMQKSGVKPDAITFVGVLAACSHAGLVDEGISHFNSMSEVYGIQPSIEHYGGMVDILGRAGRIAEAEELIRKMQXPPDRFVL 518          

Query:   43 TLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEA 498
            +LL  C +  A   G+ +HA++ K      + L T L+  Y  C  ++DA  V  ++P ++V++WTA+IS ++  G   +AL  F +M +SG +P+  TF  VL +C+      +     +S+      +  I     ++D+  +AGRI EA
Sbjct:  351 SLLLACSHLGALELGKWLHAYIEKEKIKVDVALGTTLVDMYAKCGSIDDALEVFRKLPEKDVMTWTALISGFAMCGQGRKALEHFHEMQKSGVKPDAITFVGVLAACSHAGLVDEGISHFNSMSEVYGIQPSIEHYGGMVDILGRAGRIAEA 502          

Query:   46 LLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCEC---LNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASE-ALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDL--GRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +++ C    +   GQ++H+ + ++       +   L+  Y  C     +NDA++V D MP  NV+SWTA+I+ Y + G   E A+ LF++M+     PN FTF+++L +CA  +   DL  G QIHSL +K+   S   VG+SL+ MY+K+G++ +AR  F+ L E++++S   I+  YA+    EEA  LF ++Q  G  ++  T++S+L+  + + A   G Q+H  +++  L S  ++ N L+ MYS+CGN+  +  +F+ M +  VISW +M+ G++KHG     V++F  M E   ++P+ +T++AVLS CSH G+ D G ++F EM + ++G  P +EHY C+VDLLGR+G + EA EFI  M F     IW + LGACRVH N+E+G+     +++  P ++  Y +LSNLYAS GRWE V  VR+ M EK +IKE G SWIE+   +H FH  D SHP+                  GYVP+   VL+DV+EEQK   L  HSEK+A+AFGLI+T +  P+RV KNLR+C DCH   K +S+  GRE+ +RD NRFHH   G CSC +YW
Sbjct:  273 VISACTKLESLSLGQQLHSWVIRSGLALGHCVGCCLVDMYAKCAADGSMNDARKVFDRMPNHNVMSWTAIINGYVQSGKGDEEAIKLFVEMMSGHVPPNHFTFSSILKACANLS---DLCKGEQIHSLAVKSGLASVNCVGNSLITMYSKSGQVEDARKSFDVLYEKNLISYNTIVDAYAKHLDAEEAFGLFHEIQDTGYGASAFTFSSLLSGAASICAAGKGEQIHARIIKSGLESNQIICNXLVSMYSRCGNIDAAFLVFNEMEDWNVISWTSMITGFAKHGYAAAAVEMFNKMLEAG-IKPNXITYIAVLSACSHAGLVDEGWKHFKEMQK-KHGVVPRMEHYACMVDLLGRSGSLVEALEFINSMPFTADELIWRTFLGACRVHGNIELGKHAAKMIIEQNPRDSAAYSLLSNLYASTGRWEEVAKVRKYMKEKYLIKEVGSSWIEVKNKIHKFHVGDTSHPKAKEIYDELDQLGSKIKKLGYVPNTDFVLHDVEEEQKGFYLFQHSEKIAVAFGLISTSKSKPIRVFKNLRVCGDCHTAIKYISEATGREIVVRDSNRFHHFKDGRCSCNEYW 845          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEM-PVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKF-ESHIFVGSSLLDMYAKAGR-IYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKC---GNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMG-KEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCV----VDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVE 1203
            +A +G+      Y  L+  C+  R F   + VH  +  +   P   L   LI  Y+       A  + + M   RN+VSW+AM+S ++      EA++ FL ML  G  PNE+ FA+V+ +C+  A    +G+ I   +IK  +  S + VG SL+DM+AK G  + EA  VFE +PE D V+ T +I+ +AQ+G   EA+ L+  +   G   +    + V++A + L +L LG+Q+H+ V+R  L     +   L+DMY+KC   G+++ +R++FD MP   V+SW A++ GY + G G +E +KLF  M     V P+  TF ++L  C++     +G E  + +A      +  L    CV    + +  ++G+VE+A +    + +E     + +++ A   H + E
Sbjct:   53 LAQRGIHPDLPTYSLLIKSCIRSRNFDLXKLVHDRLAHSQLEPDQVLLNSLISLYSKSGDWKKANSIFENMGSERNLVSWSAMVSCFANNDMGFEAISTFLDMLEHGFYPNEYCFASVIRACSN-ARNIGIGKVIFGSVIKGGYLGSDVCVGCSLIDMFAKGGGDLGEAYKVFEEMPETDAVTWTLMITRFAQMGFPREAIGLYVDMLLSGFMPDQFALSGVISACTKLESLSLGQQLHSWVIRSGLALGHCVGCCLVDMYAKCAADGSMNDARKVFDRMPNHNVMSWTAIINGYVQSGKGDEEAIKLFVEMM-SGHVPPNHFTFSSILKACANLSDLCKG-EQIHSLA-----VKSGLASVNCVGNSLITMYSKSGQVEDARKSFDVL-YEKNLISYNTIVDAYAKHLDAE 455          

Query:   37 YYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTS----CAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLG-------RQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMP-ERTVISWNAMLVGYSKHG---MGKEVVKL 903
            + ++L  C N     +G+++H+   K+       +   LI  Y+    + DA++  D +  +N++S+  ++ AY+K   A EA  LF ++  +G   + FTF+++L+     CA G      G QIH+ IIK+  ES+  + + L+ MY++ G I  A  VF  + + +V+S T++I+G+A+ G    A+E+F ++   G+  N +TY +VL+A S    +D G       ++ H  V R E  +       ++D+  + G+L  +    +SMP     + W   L     HG   +GK   K+
Sbjct:  375 FSSILKACANLSDLCKGEQIHSLAVKSGLASVNCVGNSLITMYSKSGQVEDARKSFDVLYEKNLISYNTIVDAYAKHLDAEEAFGLFHEIQDTGYGASAFTFSSLLSGAASICAAGK-----GEQIHARIIKSGLESNQIICNXLVSMYSRCGNIDAAFLVFNEMEDWNVISWTSMITGFAKHGYAAAAVEMFNKMLEAGIKPNXITYIAVLSACSHAGLVDEGWKHFKEMQKKHGVVPRMEHYA------CMVDLLGRSGSLVEALEFINSMPFTADELIWRTFLGACRVHGNIELGKHAAKM 667          

Query:  586 EALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSM-PERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGC-VVDLLGR-AGRVEEAFEFIKKMRFEPTAAIW 1161
            +A+     L + G+  +  TY+ ++ +       DL + VH+ +   +L    VL NSLI +YSK G+   +  IF++M  ER ++SW+AM+  ++ + MG E +  F  M E     P+   F +V+  CS+      G   F  + +G  G        GC ++D+  +  G + EA++  ++M  E  A  W
Sbjct:   45 KAITTLDLLAQRGIHPDLPTYSLLIKSCIRSRNFDLXKLVHDRLAHSQLEPDQVLLNSLISLYSKSGDWKKANSIFENMGSERNLVSWSAMVSCFANNDMGFEAISTFLDMLEHG-FYPNEYCFASVIRACSNARNIGIGKVIFGSVIKG--GYLGSDVCVGCSLIDMFAKGGGDLGEAYKVFEEMP-ETDAVTW 235          

Query:   40 YTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPR------------RHRGVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            + +L  C    A  EG+  HAH+ +            LI  Y+ C  L+ A +V DEMP R++VSW  MI + ++ G   EAL LFLQM R G   +EFT ++VL +CA     F+  +Q+H+L +K     +++VG++LLD+YAK+G I  A  VFE LPER  V+ +++++GY Q  L EEAL LF + +R G+  N  T +S + A +GLAAL  G+QVH  + +    S + + +SLIDMY+KCG++  +  +F+ M ER ++ WNAM+ G+++H    EV+ LF+ M++   + P  VT+ +VL+ CSH G+ + G +YF  M   E+   P + HY C+VD+LGR+G + EA++ I+K+ F  TA++WGSLL +CR+H N+++ E     L +IEP NAGN+++LSN+YA+  +WE V   R+++ E+ + KE G+SWIE+   +H+F   +R H R                + GY  +    L+ V E +K ++L  HSEK+AL FGL+  P   P+R+ KNLRIC DCH F K+ S   GRE+ +RD NRFHH   G CSCG++W
Sbjct:   54 HEILQICAGTGAPAEGKACHAHIIRFGLTADTLTSNMLINMYSKCGLLDCAGKVFDEMPERSLVSWNTMIGSLARNGEEQEALGLFLQMQRQGNTFSEFTVSSVLCACAVKCAVFE-SKQLHALAVKLAMNLNVYVGTALLDVYAKSGLIKXASSVFESLPERSDVTWSSMVAGYVQNELFEEALVLFHRAKRIGLEQNQFTVSSAICACAGLAALIEGKQVHALLSKTGFGSNIFIVSSLIDMYAKCGSIREAYSVFEGMSERNIVLWNAMISGFARHACSLEVMILFEKMQQMG-MFPSKVTYASVLTACSHLGLVESGKKYFNLMI-AEHNVSPNVVHYSCMVDILGRSGLIIEAYDLIQKIPFGVTASMWGSLLASCRIHGNLDLAEVAAKHLSEIEPNNAGNHILLSNVYAANKKWEEVARTRKILKERELKKERGKSWIEIKDKVHSFMVGERKHARIDEIYSKLDDLVTELKIMGYKAETEHDLHCVGESRKHELLRHHSEKLALTFGLMCLPSNAPIRIXKNLRICXDCHAFMKISSSCRGREIIVRDTNRFHHFKNGYCSCGEFW 624          

Query:   13 GLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLP 522
            GLE       + +  C    A  EG++VHA ++KT +   + + + LI  Y  C  + +A  V + M  RN+V W AMIS +++  C+ E + LF +M + G  P++ T+A+VLT+C+         +  + +I +     ++   S ++D+  ++G I EA  + + +P
Sbjct:  247 GLEQNQFTVSSAICACAGLAALIEGKQVHALLSKTGFGSNIFIVSSLIDMYAKCGSIREAYSVFEGMSERNIVLWNAMISGFARHACSLEVMILFEKMQQMGMFPSKVTYASVLTACSHLGLVESGKKYFNLMIAEHNVSPNVVHYSCMVDILGRSGLIIEAYDLIQKIP 416          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M  +G+E     + ++L    +  A   G +VH  + ++     + +++ L+  Y  C  LN A++ L  M V NVVSW +MI    ++G A EAL+LF  M     + + FT+ +VL S A           IH LIIKT F+ +  VG++L+DMYAK G I  A  VF+C+ ++DV+S T++I+GY + G  E+AL LF +++  G+  +    AS L+A + L  L+ G+Q+H + ++  L + + + NS + MY+KCG +  + ++FDSM  + VI+W A++VGY+++G GKE +K +  M       PD +TF+ ++  CSH G+ ++G  Y++E+     G +P  EHY C++DLLGR+G++ EA   + KM  EP   +W +LL ACRVH N+E+GE     L ++EP NA  YV LSN+Y++  RWE    +R LM  K ++KEPG SWIE +  +HTF + DRSH R                 AGYVPD+   L+D+D+E KE  L  HSEK+A+AFGL+ TP G P+R+ KNLR+C DCH   K +SK+Y R + LRD N FHH   G CSC DYW
Sbjct:  301 MRAEGVESNQFTFPSVLTASASVLAHSFGAQVHGCVVQSGLGANVFVQSSLVDMYVKCGDLNSAKKALRSMEVDNVVSWNSMIVGCVRQGFAEEALSLFKDMRSREMKIDHFTYPSVLNSFAVMK-DMTNAMSIHCLIIKTGFDVYQLVGNALVDMYAKQGNIDAAVEVFKCMSDKDVISWTSLITGYVRNGSHEKALRLFCEMRTAGIYPDQFVIASALSASAELTVLEFGQQIHANFIKSGLQASLSVDNSFVAMYAKCGCIEDANKVFDSMQVQDVITWTALIVGYAQNGRGKESLKFYDQMILTG-AEPDFITFIGLIFACSHAGLLEKG-RYYFELMSRVYGIQPGSEHYACMIDLLGRSGKLNEAEALVNKMVVEPDGTVWKALLAACRVHGNIELGERAAMNLFKLEPLNAVPYVQLSNMYSAASRWEDAARIRRLMKSKGILKEPGCSWIETNSQVHTFMSEDRSHSRTAEIYSKVDEIMMLIKEAGYVPDMNFALHDMDKEGKELGLAYHSEKLAVAFGLLTTPPGAPIRIFKNLRVCGDCHTAMKFISKVYLRHIILRDSNCFHHFKEGNCSCDDYW 884          

Query:  151 LIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPER-DVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLL-GACRVHSNVE-IGEFVGFRLLQIEPENAGNYVILSNLYAS 1290
            +I  Y N   L +A+++ D  P +N ++W+++IS Y +    SEA  LF +M   G +P+++T  +VL  C+        G  +H  + KT+F+++IFV + L+DMYAK  RI EA  +FE L +R + V  T +++GY+Q G   +A++ FR ++ EG+ SN  T+ SVLTA + + A   G QVH  V++  L + V +Q+SL+DMY KCG+L+ +++   SM    V+SWN+M+VG  + G  +E + LFK M+   +++ D  T+ +VL+  S   M+D            + G +        +VD+  + G ++ A E  K M  +     W SL+ G  R  S+ + +  F   R   I P+    +VI S L AS
Sbjct:  148 MIAAYANSGRLAEAKQLFDATPSKNSITWSSLISGYCRNESESEAFELFWRMQFEGHKPSQYTLGSVLRLCSTLGL-LQRGALVHGYMTKTQFDNNIFVVTGLVDMYAKCKRISEAEYLFETLFDRKNHVLWTVMLTGYSQNGDGFKAMKFFRDMRAEGVESNQFTFPSVLTASASVLAHSFGAQVHGCVVQSGLGANVFVQSSLVDMYVKCGDLNSAKKALRSMEVDNVVSWNSMIVGCVRQGFAEEALSLFKDMR-SREMKIDHFTYPSVLN--SFAVMKDMTNAMSIHCLIIKTGFDVYQLVGNALVDMYAKQGNIDAAVEVFKCMS-DKDVISWTSLITGYVRNGSHEKALRLFCEMRTAGIYPD---QFVIASALSAS 522          

Query:   22 MKFEGY----YTL---LNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEM-PVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCS-----------HGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVD-------------------LLGRA--GRVEEAFEFIKKMRF---EPTAAIWGSLLGACRVHSNVEIGEF---VGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSW 1371
            M+FEG+    YTL   L  C      + G  VH +MTKT +   + + T L+  Y  C+ +++A+ + + +   +N V WT M++ YS+ G   +A+  F  M   G E N+FTF +VLT+ A        G Q+H  ++++   +++FV SSL+DMY K G +  A+     +   +VVS  ++I G  + G  EEAL LF+ ++   M  ++ TY SVL + + +  +     +H  +++     Y ++ N+L+DMY+K GN+  +  +F  M ++ VISW +++ GY ++G  ++ ++LF  M+    + PD     + LS  +           H      GL+    +   +N         GC+ D                   ++G A  GR +E+ +F  +M     EP    +  L+ AC     +E G +   +  R+  I+P  + +Y  + +L   +GR  G  N  E +V K V++  G  W
Sbjct:  199 MQFEGHKPSQYTLGSVLRLCSTLGLLQRGALVHGYMTKTQFDNNIFVVTGLVDMYAKCKRISEAEYLFETLFDRKNHVLWTVMLTGYSQNGDGFKAMKFFRDMRAEGVESNQFTFPSVLTASA-SVLAHSFGAQVHGCVVQSGLGANVFVQSSLVDMYVKCGDLNSAKKALRSMEVDNVVSWNSMIVGCVRQGFAEEALSLFKDMRSREMKIDHFTYPSVLNSFAVMKDMTNAMSIHCLIIKTGFDVYQLVGNALVDMYAKQGNIDAAVEVFKCMSDKDVISWTSLITGYVRNGSHEKALRLFCEMRTAG-IYPDQFVIASALSASAELTVLEFGQQIHANFIKSGLQASLSV---DNSFVAMYAKCGCIEDANKVFDSMQVQDVITWTALIVGYAQNGRGKESLKFYDQMILTGAEPDFITFIGLIFACSHAGLLEKGRYYFELMSRVYGIQP-GSEHYACMIDL---LGR-SGKLNEAEALVNKMVVEPDGTVW 684          

Query:  442 FVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPER-TVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGAC 1182
            F  ++++  YA +GR+ EA+ +F+  P ++ ++ +++ISGY +   + EA ELF ++Q EG   +  T  SVL   S L  L  G  VH ++ + +  + + +   L+DMY+KC  +S +  +F+++ +R   + W  ML GYS++G G + +K F+ M+ E  V  +  TF +VL+  +       G +    + +   G    ++    +VD+  + G +  A + ++ M  +   + W S++  C
Sbjct:  143 FSWNTMIAAYANSGRLAEAKQLFDATPSKNSITWSSLISGYCRNESESEAFELFWRMQFEGHKPSQYTLGSVLRLCSTLGLLQRGALVHGYMTKTQFDNNIFVVTGLVDMYAKCKRISEAEYLFETLFDRKNHVLWTVMLTGYSQNGDGFKAMKFFRDMRAEG-VESNQFTFPSVLTASASVLAHSFGAQVHGCVVQSGLGANVFVQ--SSLVDMYVKCGDLNSAKKALRSMEVDNVVS-WNSMIVGC 386          

Query:  754 NSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVE 1107
            N L++  SK G +  +R++FD MP R   SWN M+  Y+  G   E  +LF     +N     S+T+ +++SG      E    E F+ M     G +P     G V+ L    G ++
Sbjct:  115 NLLLNELSKSGRVDEARQMFDKMPSRDEFSWNTMIAAYANSGRLAEAKQLFDATPSKN-----SITWSSLISGYCRNESESEAFELFWRMQ--FEGHKPSQYTLGSVLRLCSTLGLLQ 225          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M +QGLE++F+GY ++L EC+++ A REGQRVHAHM KTCY PP++LRTRLIV YN C CL DA+RVLDEMP RNVVSWTAMIS YS+RG ASEAL+LF++ML SGT PNEFTFATVLTSC   + GF LGRQIHSL+IKT FESHIFVGSSLLDMYAKAG+I EAR VF+ LPERDVVSCTAIISGYAQLGLDEEAL+LFR+LQREGM SNYVTYASVLTALSGLAALD GRQVH+HVLR +LP YVVLQNSLIDMYSKCG+L+YSRRIFDSMPERTVISWNAMLVGYSKHG+G+E V+LFKLMKEENKV+PDSVTFLAVLSGCSHGGMEDRGLE FYEM   ++G EPE+EHYGCVVDL GRAGRVEEAFEFIKKM FEPTAAIWGSLLGACRVH NV IGEFV  RLL+IE ENAGNYVILSNLYAS GRW+ VR VRELM EKAVIKEPGRSWIELDQ LHTFHASDRSHPR+                AGYVP+L CVLYDVD+EQKEK+L GHSEK+ALAFGLI TP G PVR+IKNLRICVDCHNFAK +S++YGREVSLRDKNRFHHIVGGTCSCGDYW
Sbjct:  468 MGIQGLEVEFQGYDSVLTECISQTAIREGQRVHAHMIKTCYEPPVYLRTRLIVLYNKCRCLGDARRVLDEMPERNVVSWTAMISGYSQRGYASEALHLFVEMLMSGTAPNEFTFATVLTSCTSSS-GFQLGRQIHSLVIKTSFESHIFVGSSLLDMYAKAGKICEARRVFDGLPERDVVSCTAIISGYAQLGLDEEALDLFRRLQREGMRSNYVTYASVLTALSGLAALDHGRQVHSHVLRAKLPFYVVLQNSLIDMYSKCGSLTYSRRIFDSMPERTVISWNAMLVGYSKHGLGREAVELFKLMKEENKVKPDSVTFLAVLSGCSHGGMEDRGLEIFYEMVNQKDGFEPEIEHYGCVVDLFGRAGRVEEAFEFIKKMPFEPTAAIWGSLLGACRVHQNVHIGEFVARRLLEIESENAGNYVILSNLYASAGRWDDVRTVRELMKEKAVIKEPGRSWIELDQTLHTFHASDRSHPRKEEVFAKVRELSIKIKEAGYVPELSCVLYDVDDEQKEKILQGHSEKLALAFGLICTPGGTPVRIIKNLRICVDCHNFAKFLSRVYGREVSLRDKNRFHHIVGGTCSCGDYW 1053          

Query:  595 ELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEA 1113
            E   ++  +G+   +  Y SVLT      A+  G++VH H+++      V L+  LI +Y+KC  L  +RR+ D MPER V+SW AM+ GYS+ G   E + LF  M       P+  TF  VL+ C+       G +    +   +   E  +     ++D+  +AG++ EA
Sbjct:  463 EALLEMGIQGLEVEFQGYDSVLTECISQTAIREGQRVHAHMIKTCYEPPVYLRTRLIVLYNKCRCLGDARRVLDEMPERNVVSWTAMISGYSQRGYASEALHLFVEMLMSG-TAPNEFTFATVLTSCTSSSGFQLGRQIHSLVI--KTSFESHIFVGSSLLDMYAKAGKICEA 632          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M +QGLE++F+GY ++L EC+++ A REGQRVHAHM KTCY PP++LRTRLIV YN C CL DA+RVLDEMP RNVVSWTAMIS YS+RG ASEAL+LF++ML SGT PNEFTFATVLTSC   + GF LGRQIHSL+IKT FESHIFVGSSLLDMYAKAG+I EAR VF+ LPERDVVSCTAIISGYAQLGLDEEAL+LFR+LQREGM SNYVTYASVLTALSGLAALD GRQVH+HVLR +LP YVVLQNSLIDMYSKCG+L+YSRRIFDSMPERTVISWNAMLVGYSKHG+G+E V+LFKLMKEENKV+PDSVTFLAVLSGCSHGGMEDRGLE FYEM   ++G EPE+EHYGCVVDL GRAGRVEEAFEFIKKM FEPTAAIWGSLLGACRVH NV IGEFV  RLL+IE ENAGNYVILSNLYAS GRW+ VR VRELM EKAVIKEPGRSWIELDQ LHTFHASDRSHPR+                AGYVP+L CVLYDVD+EQKEK+L GHSEK+ALAFGLI TP G PVR+IKNLRICVDCHNFAK +S++YGREVSLRDKNRFHHIVGGTCSCGDYW
Sbjct:    1 MGIQGLEVEFQGYDSVLTECISQTAIREGQRVHAHMIKTCYEPPVYLRTRLIVLYNKCRCLGDARRVLDEMPERNVVSWTAMISGYSQRGYASEALHLFVEMLMSGTAPNEFTFATVLTSCTSSS-GFQLGRQIHSLVIKTSFESHIFVGSSLLDMYAKAGKICEARRVFDGLPERDVVSCTAIISGYAQLGLDEEALDLFRRLQREGMRSNYVTYASVLTALSGLAALDHGRQVHSHVLRAKLPFYVVLQNSLIDMYSKCGSLTYSRRIFDSMPERTVISWNAMLVGYSKHGLGREAVELFKLMKEENKVKPDSVTFLAVLSGCSHGGMEDRGLEIFYEMVNQKDGFEPEIEHYGCVVDLFGRAGRVEEAFEFIKKMPFEPTAAIWGSLLGACRVHQNVHIGEFVARRLLEIESENAGNYVILSNLYASAGRWDDVRTVRELMKEKAVIKEPGRSWIELDQTLHTFHASDRSHPRKEEVFAKVRELSIKIKEAGYVPELSCVLYDVDDEQKEKILQGHSEKLALAFGLICTPGGTPVRIIKNLRICVDCHNFAKFLSRVYGREVSLRDKNRFHHIVGGTCSCGDYW 586          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+QG E+KF+GY  LLNECVN+RA REGQRVHAHM KTCYLPP++L TRLI+ Y  CECL  A+ V DEM  RNVVSWTAMIS YS+RG ASEAL+LF+QMLRS TEPNEFTFATVL+SC G + GF+LGRQIHS I K  +E+HIFVGSSLLDMYAKAGRI+EARGVFECLPERDVVSCTAIISGYAQLGLDEEALELF +LQREGM+SNYVTYAS+LTALSGLAALD G+QVH+HVLR ELP YVVLQNSLIDMYSKCGNL+Y+R+IF++MP RTVISWNAMLVGYSKHG G EVVKLFKLM+EENKV+PDSVTFLAVLSGCSHGG+ED+GLE F EM  G +  E  +EHYGCV+DLLGRAGRVEEAFE IKKM FEPTAAIWGSLLGACRVHSN  IGEFVG RLL+IEPENAGNYVILSNLYAS GRWE VRNVRELM+EKAVIKEPGRSWIELDQ +HTF+ASDRSHPRR                +GYVPD  CVLYDVDEEQKEK+LLGHSEK+ALAFGLI+T EGVP+RVIKNLRICVDCHNFAK VSK+YGR+VS+RDKNRFHH+ GG CSCGDYW
Sbjct:    1 MAIQGPEIKFDGYNMLLNECVNKRAVREGQRVHAHMIKTCYLPPVYLSTRLIILYTKCECLGCARHVFDEMRERNVVSWTAMISGYSQRGFASEALHLFVQMLRSDTEPNEFTFATVLSSCTGFS-GFELGRQIHSHIFKRNYENHIFVGSSLLDMYAKAGRIHEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFCRLQREGMSSNYVTYASLLTALSGLAALDHGKQVHSHVLRCELPFYVVLQNSLIDMYSKCGNLNYARKIFNNMPVRTVISWNAMLVGYSKHGKGIEVVKLFKLMREENKVKPDSVTFLAVLSGCSHGGLEDKGLEMFDEMMNGGDEIEAGIEHYGCVIDLLGRAGRVEEAFELIKKMPFEPTAAIWGSLLGACRVHSNTNIGEFVGCRLLEIEPENAGNYVILSNLYASAGRWEDVRNVRELMMEKAVIKEPGRSWIELDQTIHTFYASDRSHPRREEVFLKVRELLVKFKESGYVPDQSCVLYDVDEEQKEKILLGHSEKLALAFGLISTSEGVPLRVIKNLRICVDCHNFAKFVSKVYGRQVSIRDKNRFHHVAGGICSCGDYW 586          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA++GL+  F+ Y T+LNEC+ +RA REGQRVHAHM KT YLP ++LRTRLIVFY  C+ L DA+ V D MP RNVVSWTAMISAYS+RG AS+AL+LF+QMLRSGTEPNEFTFATVLTSC G + GF LGRQIHS IIK  +E+H++VGSSLLDMYAK G+I+EARG+F+CLPERDVVSCTAIISGYAQLGLDEEALELFR+LQREGM SNYVTY SVLTALSGLAALD G+QVHNH+LR E+PSYVVLQNSLIDMYSKCGNL+Y+RRIFD++ ERTVISWNAMLVGYSKHG G+EV++LF LM +ENKV+PDSVT LAVLSGCSHGG+ED+G++ FY+M  G+   +P+ +HYGCVVD+LGRAGRVE AFEF+KKM FEP+AAIWG LLGAC VHSN++IGEFVG +LLQIEPENAGNYVILSNLYAS GRWE VR++R LM++KAV KEPGRSWIELDQ+LHTFHASD SHPRR                AGYVPDL CVL+DVDEEQKEK+LL HSEK+AL FGLIATPE VP+RVIKNLRICVDCHNFAK  SKIYGREVSLRDKNRFH IVGG CSCGDYW
Sbjct:   49 MALRGLDTNFQDYNTVLNECLRKRAIREGQRVHAHMIKTHYLPCVYLRTRLIVFYVKCDSLRDARHVFDVMPERNVVSWTAMISAYSQRGYASQALSLFVQMLRSGTEPNEFTFATVLTSCIGSS-GFVLGRQIHSHIIKLNYEAHVYVGSSLLDMYAKDGKIHEARGIFQCLPERDVVSCTAIISGYAQLGLDEEALELFRRLQREGMQSNYVTYTSVLTALSGLAALDHGKQVHNHLLRSEVPSYVVLQNSLIDMYSKCGNLTYARRIFDTLHERTVISWNAMLVGYSKHGEGREVLELFNLMIDENKVKPDSVTVLAVLSGCSHGGLEDKGMDIFYDMTSGKISVQPDSKHYGCVVDMLGRAGRVEAAFEFVKKMPFEPSAAIWGCLLGACSVHSNLDIGEFVGHQLLQIEPENAGNYVILSNLYASAGRWEDVRSLRNLMLKKAVTKEPGRSWIELDQVLHTFHASDCSHPRREEVSAKVQELSARFKEAGYVPDLSCVLHDVDEEQKEKILLSHSEKLALTFGLIATPESVPIRVIKNLRICVDCHNFAKYTSKIYGREVSLRDKNRFHRIVGGKCSCGDYW 634          

Query:  580 DEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGC--SHGGMEDRG-----LEYFYEM--------------------AEGENGTEPELEHYGCVVDLLGRA--GRVEEAFEFIKKMR---FEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSN----LYASVGRWEGVRNVRELMVEKAVI 1350
            D    E    +   G+ +N+  Y +VL       A+  G++VH H+++      V L+  LI  Y KC +L  +R +FD MPER V+SW AM+  YS+ G   + + LF  M       P+  TF  VL+ C  S G +  R      ++  YE                     A G     PE +   C   + G A  G  EEA E  ++++    +     + S+L A    + ++ G+ V   LL+ E     +YV+L N    +Y+  G     R + + + E+ VI
Sbjct:   39 DTRLREALLHMALRGLDTNFQDYNTVLNECLRKRAIREGQRVHAHMIKTHYLPCVYLRTRLIVFYVKCDSLRDARHVFDVMPERNVVSWTAMISAYSQRGYASQALSLFVQMLRSG-TEPNEFTFATVLTSCIGSSGFVLGRQIHSHIIKLNYEAHVYVGSSLLDMYAKDGKIHEARGIFQCLPERDVVSCTAIISGYAQLGLDEEALELFRRLQREGMQSNYVTYTSVLTALSGLAALDHGKQVHNHLLRSE---VPSYVVLQNSLIDMYSKCGNLTYARRIFDTLHERTVI 327          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSG---------------------TEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G  MKFE Y  +LNECVN+RAFREGQRVHAHM KT YLP + LRTRLIV Y  C+ L DA  V DEMP RNVVSWTAMISAYS+RG AS+ALNLF   ++                       TEPNEFTFATVLTSC     GF LGRQIHSLIIK  +E H+FVGSSLLDMYAK G+I+EAR VFECLPERDVVSCTAIISGYAQLGLDEEALELFR+LQ EGM SNYVTY  VLTALSGLAALDLG+QVHNHVLR E+PS+VVLQNSLIDMYSKCGNL+YSRRIFD+M ERTVISWNAMLVGYSKHG G+EV+KLF LM+EE KV+PDSVT LAVLSGCSHGG+ED+GL  F +M+ G+   EP++EHYGCVVDLLGR+GRVEEAFEFIKKM FEPTAAIWGSLLGACRVHSNV+IGEF G +LL+IEP NAGNYVILSNLYAS GRWE V ++R+LM++K V KEPGRS IELDQ+LHTFHASDRSHPRR                 GYVPDL CVL+DVDEEQKEK+LLGHSEK+AL+FGLIA+P  VP+RVIKNLRICVDCHNFAK +SK+YGREVSLRDKNRFH IVGG CSC DYW
Sbjct:  234 MALHGFNMKFENYNAILNECVNKRAFREGQRVHAHMIKTRYLPSVFLRTRLIVLYTKCDSLGDAHNVFDEMPERNVVSWTAMISAYSQRGYASQALNLFFADVKISLTGVYAIDKLKLSNPNRPWVCTEPNEFTFATVLTSCTSSL-GFILGRQIHSLIIKLNYEDHVFVGSSLLDMYAKDGKIHEARTVFECLPERDVVSCTAIISGYAQLGLDEEALELFRRLQGEGMKSNYVTYTGVLTALSGLAALDLGKQVHNHVLRSEIPSFVVLQNSLIDMYSKCGNLTYSRRIFDTMYERTVISWNAMLVGYSKHGEGREVLKLFTLMREETKVKPDSVTILAVLSGCSHGGLEDKGLNIFNDMSSGKIEVEPKMEHYGCVVDLLGRSGRVEEAFEFIKKMPFEPTAAIWGSLLGACRVHSNVDIGEFAGQQLLEIEPGNAGNYVILSNLYASAGRWEDVSSLRDLMLKKTVTKEPGRSSIELDQVLHTFHASDRSHPRREEICMKVKELSTSFKEVGYVPDLSCVLHDVDEEQKEKILLGHSEKLALSFGLIASPASVPIRVIKNLRICVDCHNFAKYISKVYGREVSLRDKNRFHRIVGGKCSCEDYW 840          

Query:  607 QLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLR-RELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLF--------------KLMKEENKVR------PDSVTFLAVLSGC--SHGGMEDR-------GLEYFYEMAEGENGTE------------------PELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSN---VEIGEFVGFRLLQIEPENAGNYVILSN----LYASVGRWEGVRNVRELMVEKAVI 1350
            Q+   G    +  Y ++L       A   G++VH H+++ R LPS V L+  LI +Y+KC +L  +  +FD MPER V+SW AM+  YS+ G   + + LF                +K  N  R      P+  TF  VL+ C  S G +  R        L Y   +  G +  +                  PE +   C   + G A  G  EEA E  ++++ E   + + +  G     S    +++G+ V   +L+ E     ++V+L N    +Y+  G     R + + M E+ VI
Sbjct:  233 QMALHGFNMKFENYNAILNECVNKRAFREGQRVHAHMIKTRYLPS-VFLRTRLIVLYTKCDSLGDAHNVFDEMPERNVVSWTAMISAYSQRGYASQALNLFFADVKISLTGVYAIDKLKLSNPNRPWVCTEPNEFTFATVLTSCTSSLGFILGRQIHSLIIKLNYEDHVFVGSSLLDMYAKDGKIHEARTVFECLPERDVVSCTAIISGYAQLGLDEEALELFRRLQGEGMKSNYVTYTGVLTALSGLAALDLGKQVHNHVLRSE---IPSFVVLQNSLIDMYSKCGNLTYSRRIFDTMYERTVI 533          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G EM F GY  LLN C+++RA R+GQRVHAHM KT YLP  +LRTRL++FY  C+CL DA++VLDEMP +NVVSWTAMIS YS+ G +SEAL +F +M+RS  +PNEFTFATVLTSC   + G  LG+QIH LI+K  ++SHIFVGSSLLDMYAKAG+I EAR +FECLPERDVVSCTAII+GYAQLGLDEEALE+F +L  EGM+ NYVTYAS+LTALSGLA LD G+Q H HVLRRELP Y VLQNSLIDMYSKCGNLSY+RR+FD+MPERT ISWNAMLVGYSKHG+G+EV++LF+LM++E +V+PD+VT LAVLSGCSHG MED GL  F  M  GE GT+P  EHYGC+VD+LGRAGR++EAFEFIK+M  +PTA + GSLLGACRVH +V+IGE VG RL++IEPENAGNYVILSNLYAS GRW  V NVR +M++KAV KEPGRSWI+ +Q LH FHA+DR+HPRR   +            AGYVPDL CVLYDVDEEQKEK+LLGHSEK+AL FGLIAT EG+P+RV KNLRICVDCHNFAK+ SK++ REVSLRDKNRFH IV G CSCGDYW
Sbjct:   43 MAMLGPEMGFHGYDALLNACLDKRALRDGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALTVFAEMMRSDGKPNEFTFATVLTSCIRAS-GLGLGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIKEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFHRLHSEGMSPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYARRLFDNMPERTAISWNAMLVGYSKHGLGREVLELFRLMRDEKRVKPDAVTLLAVLSGCSHGRMEDTGLNIFDGMVAGEYGTKPGTEHYGCIVDMLGRAGRIDEAFEFIKRMPSKPTAGVLGSLLGACRVHLSVDIGESVGRRLIEIEPENAGNYVILSNLYASAGRWADVNNVRAMMMQKAVTKEPGRSWIQHEQTLHYFHANDRTHPRREEVLAKMKEISIKMKQAGYVPDLSCVLYDVDEEQKEKMLLGHSEKLALTFGLIATGEGIPIRVFKNLRICVDCHNFAKIFSKVFEREVSLRDKNRFHQIVDGICSCGDYW 628          

Query:  508 FECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLF-KLMKEENKVRPDSVTFLAVLSGC----------------------SHGGMEDRGLEYFYEMAEGENGTE-----PELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFE---PTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIE-PENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVI 1350
            F   P   V+     IS     G  +EAL     L   G    +  Y ++L A     AL  G++VH H+++        L+  L+  Y KC  L  +R++ D MPE+ V+SW AM+  YS+ G   E + +F ++M+ + K  P+  TF  VL+ C                      SH  +    L+ + +  + +   E     PE +   C   + G A  G  EEA E   ++  E   P    + SLL A    + ++ G+     +L+ E P  A     L ++Y+  G     R + + M E+  I
Sbjct:   12 FSSSPTNYVLQTILPISQLCSNGRLQEALLEMAML---GPEMGFHGYDALLNACLDKRALRDGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALTVFAEMMRSDGK--PNEFTFATVLTSCIRASGLGLGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIKEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFHRLHSEGMSPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYARRLFDNMPERTAI 321          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHRGV------------AGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            M + G E+ F  Y  LLN C+++RA REGQRVHAHM KT YLP  +LRTRL++FY  C+CL DA++VLDEMP +NVVSWTAMIS YS+ G +SEAL++F +M+RS  +PNEFTFATVLTSC   + G  LG+QIH LI+K  ++SHIFVGSSLLDMYAKAG+I EAR +FECLPERDVVSCTAII+GYAQLGLDEEALE+F++LQ EGM  NYVTYAS+LTALSGLA LD G+Q H HVLRRELP Y VLQNSLIDMYSKCGNLSY++R+FD+MPERT ISWNAMLVGYSKHG+G+EV++LF+LM++E +V+PD+VT LAVLSGCSHG MED GL  +  M  GE G +P+ EHYGC+VD+LGRAGR++EAFEFIK+M  +PTA + GSLLGACRVH +V+IGE+VG RL++IEPENAGNYVILSNLYAS GRWE V NVR +M++KAV KEPGRSWI+ +Q LH FHA+DR+HPRR   +            AGYVPD+ CVLYDVDEEQKEK+LLGHSEK+AL FGLI T EG+P+RV KNLRICVDCHNFAK+ SK++ REVSLRDKNRFH IV G CSCGDYW
Sbjct:   42 MVMLGPEIGFHCYDALLNACLDKRALREGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALSVFAEMMRSDGKPNEFTFATVLTSCIRAS-GLALGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIEEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFQRLQSEGMRPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYAQRLFDNMPERTAISWNAMLVGYSKHGLGREVLELFRLMRDEKRVKPDAVTLLAVLSGCSHGKMEDTGLSIYDGMVAGEYGIKPDTEHYGCIVDMLGRAGRIDEAFEFIKRMPSKPTAGVLGSLLGACRVHLSVDIGEYVGHRLIEIEPENAGNYVILSNLYASAGRWEDVNNVRAMMMQKAVTKEPGRSWIQHEQTLHYFHANDRTHPRREEVLAKMKEISIKMKQAGYVPDISCVLYDVDEEQKEKMLLGHSEKLALTFGLITTGEGIPIRVFKNLRICVDCHNFAKIFSKVFEREVSLRDKNRFHQIVKGICSCGDYW 627          

Query:  565 AQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLF-KLMKEENKVRPDSVTFLAVLSGC----------------------SHGGMEDRGLEYFYEMAEGENGTE-----PELEHYGCVVDLLGRA--GRVEEAFEFIKKMRFE---PTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIE-PENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVI 1350
            +QL  +    E   ++   G    +  Y ++L A     AL  G++VH H+++        L+  L+  Y KC  L  +R++ D MPE+ V+SW AM+  YS+ G   E + +F ++M+ + K  P+  TF  VL+ C                      SH  +    L+ + +  + E   E     PE +   C   + G A  G  EEA E  ++++ E   P    + SLL A    + ++ G+     +L+ E P  A     L ++Y+  G     + + + M E+  I
Sbjct:   27 SQLCSNGRLQEALLEMVMLGPEIGFHCYDALLNACLDKRALREGQRVHAHMIKTRYLPATYLRTRLLIFYGKCDCLEDARKVLDEMPEKNVVSWTAMISRYSQTGHSSEALSVFAEMMRSDGK--PNEFTFATVLTSCIRASGLALGKQIHGLIVKWNYDSHIFVGSSLLDMYAKAGQIEEAREIFECLPERDVVSCTAIIAGYAQLGLDEEALEMFQRLQSEGMRPNYVTYASLLTALSGLALLDHGKQAHCHVLRRELPFYAVLQNSLIDMYSKCGNLSYAQRLFDNMPERTAI 320          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDY 1722
            M + GL+M  + Y T+LNECV++RAF+EGQRVHAH  KT YLP ++L TRLIVFY  C+ L DA+ VL+EMP RNVVSWTAMISAYS+RG AS+AL++ +Q+LRSGTE NEFTFAT +        GF L   IHSLIIK  F++H++VGSSLLDMYAK G+I+EARG+FECLPERDVVSCTAIISGYAQL LDEE LELF +LQREGM SNYVTY SVLTALSGLAALD G+QVHNH+L  E+PS+V+LQNSLIDMYSKCGNL+Y+RRIFD+M ERTVISWNAMLVGYSKHG  +EV++LF LM++ENKV+PDSVT LAVLSGCSHGG ED+G++ FY+M  G+   +P+ + YGCVVDLLGRAGRVEEAFEFIKK+ FEP+AAI G LLGAC VHSN+ IGEFVG RLL+ EPENAGNYVILSNLYAS GRWE V ++R LM++KAV KEPGRS IE+DQ+L TFH SD SHPRR                AGY PDL CVL+DVDEEQKEK+LL HSEK+AL+FGLIATPE V + VIKNLRICVDCHNFAK +SKIY REVSLRDKN FH IVG  CSCGDY
Sbjct:   17 MTLXGLDMNLQDYNTVLNECVSKRAFKEGQRVHAHTIKTHYLPCVYLWTRLIVFYTKCDSLGDARHVLNEMPERNVVSWTAMISAYSQRGYASQALSILVQILRSGTESNEFTFAT-MPYFMYRFLGFCLREAIHSLIIKLNFKAHVYVGSSLLDMYAKDGKIHEARGIFECLPERDVVSCTAIISGYAQLDLDEE-LELFLRLQREGMXSNYVTYTSVLTALSGLAALDHGKQVHNHLLCSEVPSFVILQNSLIDMYSKCGNLTYARRIFDTMRERTVISWNAMLVGYSKHGERREVLELFNLMRDENKVKPDSVTVLAVLSGCSHGGQEDKGMDIFYDMTSGKISVQPDTKRYGCVVDLLGRAGRVEEAFEFIKKIPFEPSAAICGCLLGACSVHSNLGIGEFVGHRLLEFEPENAGNYVILSNLYASAGRWEDVTSLRNLMLKKAVTKEPGRSLIEVDQVLQTFHPSDCSHPRREEVSAKXQELLVRFKEAGYFPDLSCVLHDVDEEQKEKILLSHSEKLALSFGLIATPESVLICVIKNLRICVDCHNFAKYISKIYSREVSLRDKNWFHGIVGEKCSCGDY 600          

Query:  580 DEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKL 903
            D    E   Q+   G+  N   Y +VL       A   G++VH H ++      V L   LI  Y+KC +L  +R + + MPER V+SW AM+  YS+ G   + + +
Sbjct:    7 DTHLREALIQMTLXGLDMNLQDYNTVLNECVSKRAFKEGQRVHAHTIKTHYLPCVYLWTRLIVFYTKCDSLGDARHVLNEMPERNVVSWTAMISAYSQRGYASQALSI 114          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            +AV G + +F  Y   +  CV R+A  EG++VHAHM K  Y PP++L TRLI+ Y  C  L+DA+ VLD MP RNVVSWTAMIS YS+ G  +EAL LF++MLR+G + NEFT ATVLTSC           Q+HSL++KT FESH+FVGSSLLDMY K+G I EAR VF+ LPERD VSCTAIISGYAQLGLD+EAL+LFRQL   GM  NYVT+ ++LT+LSGLA+L+ G+QVH  +LR+ELP ++VLQNSLIDMYSKCG L YSRR+FD+MP+R+ ISWNAML+GY +HG+G+EVV+LF+ M EE  V+PDSVT LAVLSGCSHGG+ D GL+ F ++   E      + HYGCV+DLLGR+G++++A + I+ M FEPT AIWGSLLGACRVH NV +GE V  +LL +EP NAGNYVILSN+YA+ G W+ V  VR+LM+E  V KEP +SWI LD+++HTFH+S+R HPR+                AG+VPDL CVL+DVD+EQKE++LLGHSEK+A+ FGL+ TP G+ ++V+KNLRICVDCHNFAK VSK+YGRE+SLRDKNRFH +  G C+CGDYW
Sbjct:   32 LAVPGADARFHDYDAAITACVERQALGEGRQVHAHMVKARYRPPVYLATRLIILYVRCGALDDARNVLDGMPERNVVSWTAMISGYSQSGRHAEALELFIRMLRAGCKANEFTLATVLTSCPVHQ-SIQQVEQVHSLVVKTNFESHMFVGSSLLDMYGKSGNIQEARKVFDMLPERDTVSCTAIISGYAQLGLDDEALDLFRQLYSSGMQCNYVTFTTLLTSLSGLASLNYGKQVHGLILRKELPFFIVLQNSLIDMYSKCGKLLYSRRVFDNMPQRSAISWNAMLMGYGRHGIGQEVVQLFRTMTEE--VKPDSVTLLAVLSGCSHGGLVDEGLDIF-DLIVKEQNAVIHIGHYGCVIDLLGRSGQLQKALDLIEHMPFEPTPAIWGSLLGACRVHINVSVGEVVAQKLLDMEPGNAGNYVILSNIYAAAGMWKDVFRVRKLMLENTVTKEPAKSWIILDKVIHTFHSSERFHPRKKDINAKIKEVYVDVKAAGFVPDLSCVLHDVDDEQKERMLLGHSEKLAITFGLMNTPPGLTIQVMKNLRICVDCHNFAKFVSKVYGREISLRDKNRFHLLKDGACTCGDYW 614          

Query:    1 MAVQGLEMKFEGYYTLLNECVNRRAFREGQRVHAHMTKTCYLPPMHLRTRLIVFYNNCECLNDAQRVLDEMPVRNVVSWTAMISAYSKRGCASEALNLFLQMLRSGTEPNEFTFATVLTSCAGGAWGFDLGRQIHSLIIKTKFESHIFVGSSLLDMYAKAGRIYEARGVFECLPERDVVSCTAIISGYAQLGLDEEALELFRQLQREGMTSNYVTYASVLTALSGLAALDLGRQVHNHVLRRELPSYVVLQNSLIDMYSKCGNLSYSRRIFDSMPERTVISWNAMLVGYSKHGMGKEVVKLFKLMKEENKVRPDSVTFLAVLSGCSHGGMEDRGLEYFYEMAEGENGTEPELEHYGCVVDLLGRAGRVEEAFEFIKKMRFEPTAAIWGSLLGACRVHSNVEIGEFVGFRLLQIEPENAGNYVILSNLYASVGRWEGVRNVRELMVEKAVIKEPGRSWIELDQILHTFHASDRSHPRRHR------------GVAGYVPDLGCVLYDVDEEQKEKVLLGHSEKMALAFGLIATPEGVPVRVIKNLRICVDCHNFAKLVSKIYGREVSLRDKNRFHHIVGGTCSCGDYW 1725
            MA+ G   +F  Y   +  C+ RRA  EG++VHA M    Y P + L TRL+  Y  C  L+DA+ VLD MP R+VVSWT MIS YS+     EAL+LF++MLR+G  PNE+T ATVLTSC+G    +  G+Q+HSL++KT FESH+FVGSSLLDMYAK+  I EAR VF+ LPERDVVSCTAIISGYAQ GLDEEAL+LFRQL  EGM  N+VT+ +++TALSGLA+LD G+QVH  +LR+ELP +V LQNSLIDMYSKCG L YSRR+FD+M ER+V+SWNAML+GY +HG+G EV+ LFK + +E  V+PDSVT LAVLSGCSHGG+ D GL+ F  + + E        HYGC++DLLGR+GR+E+A   I+ M FE T +IWGSLLGACRVH+NV +GE V  +LL++EPENAGNYVILSN+YA+ G W+ V  VR+LM+EK V KEPG+SWI LD+++HTFH+S+R HP +                AG+VPDL CVL+DVD+EQKE++LLGHSEK+A+ FGL+ TP G+ +RV+KNLRICVDCHNFAK VSK+Y RE+SLRDKNRFH +  G C+CGDYW
Sbjct:    1 MALPGASARFHEYEAAITACIERRALWEGRQVHARMITARYRPAVFLGTRLVTMYVRCGALDDARNVLDRMPERSVVSWTTMISGYSQTERHVEALDLFIKMLRAGCIPNEYTLATVLTSCSGPQSIYQ-GKQVHSLLVKTNFESHMFVGSSLLDMYAKSENIQEARRVFDTLPERDVVSCTAIISGYAQKGLDEEALDLFRQLYSEGMQCNHVTFTTLVTALSGLASLDYGKQVHALILRKELPFFVALQNSLIDMYSKCGKLLYSRRVFDNMLERSVVSWNAMLMGYGRHGLGHEVISLFKDLHKE--VKPDSVTLLAVLSGCSHGGLVDEGLDIFDTVVK-EQSALLHTGHYGCIIDLLGRSGRLEKALNLIENMPFESTPSIWGSLLGACRVHANVHVGELVAQKLLEMEPENAGNYVILSNIYAAAGMWKDVFKVRKLMLEKTVTKEPGQSWIILDKVIHTFHSSERFHPSKKDINAKIKEIFVDIKAAGFVPDLSCVLHDVDDEQKERMLLGHSEKLAITFGLMNTPPGLTIRVMKNLRICVDCHNFAKFVSKVYEREISLRDKNRFHLLTHGNCTCGDYW 583