MDP0000222134, MDP0000222134 (mRNA) Malus spp. (apple)

Query:    1 MRTLLKPLLAQDPRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEET---MEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +R LL+P+L   P   S YAPIFQ LT  N +KLGQQ HAQ+ L G +P+A+L AKMVAMYASS DLDSAV +F R++NPS+LLYNSIIRAYT HG        +E Y RMH LGL  DNFT PFVLK CA+LSR+ +G+CVHG  L+VGLE D YVG SLI+MYVKC  + DAR+LFDKM VRD++SWNALIAGYMK+GEI +AEDLF +M  RNIVSWTAMISGYTQNG AEQAL LFDEML+  S++KPNWVTI+SVLPACA SAALERGR+IH+FA+ IGL  N S+QTAL  MYAKC SL++AR CF+ +     NL+AWNTMITAYASHG G EAVS FE+M+ AGVQPD +TF GLLSGCSHSGL+D GL +F+ M  ++SVEP VEHYACVVDLLGRAGRL EAK+LI +MPMQAGPS+WGA+L+ACR H NLEIAE+AAR LF+LEP+NSGNYV+LSN+YAEAGMW+EV  LR LLK QG+KK+PGCSW E+NGK+HLF+G D SHPQAKEIY+F L+ LP+KIK AGY+PDTSFVLHD+SEEEKE++LTTHSEKLAIAFGLLNT PGVVLRVTKNLRICGDCH ATK IS+IYEREIIVRDLNRFH FKDG+CSCGDYW
Sbjct:   63 LRILLQPILQHFPH-PSSYAPIFQFLTRHNFIKLGQQAHAQIVLHGLQPNAFLAAKMVAMYASSGDLDSAVVVFDRIDNPSSLLYNSIIRAYTRHGXXXXXXXXLEAYARMHFLGLLGDNFTLPFVLKSCADLSRVCMGRCVHGQGLRVGLEGDFYVGASLIDMYVKCGVIGDARKLFDKMIVRDMASWNALIAGYMKEGEIGVAEDLFERMEHRNIVSWTAMISGYTQNGFAEQALGLFDEMLQDGSEMKPNWVTIVSVLPACAQSAALERGRRIHDFANGIGLHLNSSVQTALAGMYAKCYSLVEARCCFDMIAQNGKNLIAWNTMITAYASHGCGVEAVSIFENMLRAGVQPDAVTFMGLLSGCSHSGLIDAGLNHFNDMGTIHSVEPRVEHYACVVDLLGRAGRLVEAKELISQMPMQAGPSVWGALLAACRSHRNLEIAELAARRLFVLEPDNSGNYVLLSNLYAEAGMWEEVKKLRALLKYQGMKKSPGCSWIEINGKSHLFMGADKSHPQAKEIYKF-LEALPEKIKMAGYIPDTSFVLHDISEEEKEYNLTTHSEKLAIAFGLLNTRPGVVLRVTKNLRICGDCHAATKFISKIYEREIIVRDLNRFHCFKDGSCSCGDYW 689          

Query:  304 MEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +E Y RMH LGL  DNFT PFVLK CA+LSR+ +G+CVHG  L+VGLE D YVG SLI+MYVKC  + DAR+LFDKM VRD++SWNALIAGYMK+GEI +AEDLF +M  RNIVSWTAMISGYTQNG AEQAL LFDEML+  S++KPNWVTI+SVLPACA SAALERGR+IH+FA+ IGL  N S+QTAL  MYAKC SL++AR CF+ +     NL+AWNTMITAYASHG G EAVS FE+M+ AGVQPD +TF GLLSGCSHSGL+D GL +F+ M  ++SVEP VEHYACVVDLLGRAGRL EAK+LI +MPMQAGPS+WGA+L+ACR H NLEIAE+AAR LF+LEP+NSGNYV+LSN+YAEAGMW+EV  LR LLK QG+KK+PGCSW E+NGK+HLF+G D SHPQAKEIY+F L+ LP+KIK AGY+PDTSFVLHD+SEEEKE++LTTHSEKLAIAFGLLNT PGVVLRVTKNLRICGDCH ATK IS+IYEREIIVRDLNRFH FKDG+CSCGDYW
Sbjct:   92 LEAYARMHFLGLLGDNFTLPFVLKSCADLSRVCMGRCVHGQGLRVGLEGDFYVGASLIDMYVKCGVIGDARKLFDKMIVRDMASWNALIAGYMKEGEIGVAEDLFERMEHRNIVSWTAMISGYTQNGFAEQALGLFDEMLQDGSEMKPNWVTIVSVLPACAQSAALERGRRIHDFANGIGLHLNSSVQTALAGMYAKCYSLVEARCCFDMIAQNGKNLIAWNTMITAYASHGCGVEAVSIFENMLRAGVQPDAVTFMGLLSGCSHSGLIDAGLNHFNDMGTIHSVEPRVEHYACVVDLLGRAGRLVEAKELISQMPMQAGPSVWGALLAACRSHRNLEIAELAARRLFVLEPDNSGNYVLLSNLYAEAGMWEEVKKLRALLKYQGMKKSPGCSWIEINGKSHLFMGADKSHPQAKEIYKF-LEALPEKIKMAGYIPDTSFVLHDISEEEKEYNLTTHSEKLAIAFGLLNTRPGVVLRVTKNLRICGDCHAATKFISKIYEREIIVRDLNRFHCFKDGSCSCGDYW 615          

Query:  140 SNPMHISAPRWSQCMQAQMIXXXXXXXXXXXXXHQRFCIIRSFGRIRYMGSLRKP 304
            SNPMH S P+W QCM A  I             H   CIIR FG I  MG L+KP
Sbjct:    3 SNPMHSSPPKWWQCMPAPGILIPLWSFLIGLITHLLCCIIRLFGLILDMGFLKKP 57          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYAS-------------------------------SDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLG--LKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI-GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDN 1062
            + +S    + + +G+ VH Q    G E D Y+GA ++ MY                                   ++  A  +F R+ + + + + ++I  YT +GF+E+ + ++  M   G  +K +  T   VL  CA+ + +  G+ +H  +  +GL  +  V T+L  MY KC  + +AR  FD +                ++G+  +A              W  MI+ Y  +G   +A+ +F+ ML+  + V+P+ VT M +L  C+HS  ++ G    N    I  +E  V     ++ +  + G L++A++   ++   Q     W  ++ A  SH     A      + V  ++PDN
Sbjct:  113 VLKSCADLSRVCMGRCVHGQGLRVGLEGDFYVGASLIDMYVKCGVIGDARKLFDKMIVRDMASWNALIAGYMKEGEIGVAEDLFERMEHRNIVSWTAMISGYTQNGFAEQALGLFDEMLQDGSEMKPNWVTIVSVLPACAQSAALERGRRIHDFANGIGLHLNSSVQTALAGMYAKCYSLVEARCCFDMIA---------------QNGKNLIA--------------WNTMITAYASHGCGVEAVSIFENMLR--AGVQPDAVTFMGLLSGCSHSGLIDAGLNHFNDMGTIHSVEPRVEHYACVVDLLGRAGRLVEAKELISQM-PMQAGPSVWGALLAACRSHRNLEIAELAARRLFV--LEPDN 445          

Query:  109 QVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            Q+HA +   G +    L  K+   YAS   LD +VA+F R  NPS   + +II  + L G  E+ +  Y +M   G++ + FT+  +LK C     I  GK +H  ++K+G +SD+YV T L+++Y +  D+  A++LFD M  + + S  A++  Y K GE+  A  LF  M  R+ V W  MI GYTQNG+  +AL LF  MLK  +K KPN VT++SVL AC    ALE GR +H++    G++ NV + TAL+ MY+KCGSL DAR  F+++     ++VAWN+MI  YA HG   EA+  F+ M   G+ P NITF G+LS C HSG V  G   F+ MK  Y +EP +EHY C+V+LLGRAG + +A +L+  M ++  P +WG +L ACR H  + + E     L      NSG Y++LSNIYA  G W  V  LR ++K  GVKK PGCS  EVN K H FL G  +HP+ KEIY  +L+E+   +K+ GY P T  VLHD+ E EKE SL  HSEKLAIAFGL+NT PG  +++ KNLR+C DCH  TKLIS+I  R+I+VRD NRFHHF +G+CSCGDYW
Sbjct:   48 QIHAVLFRHGLDHHPILNFKLQRSYASLGRLDYSVALFGRTQNPSVFFWTAIIHGHALRGLHEQALNFYAQMLTQGVEPNAFTFSSILKLCP----IEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLK--AKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKI--DDKDVVAWNSMIVGYAMHGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARLRTMMKDSGVKKEPGCSSIEVNNKVHEFLAGGLNHPKRKEIY-MMLEEINGWLKSHGYTPQTDIVLHDIGETEKERSLEVHSEKLAIAFGLINTQPGTTIKIVKNLRVCADCHEVTKLISKITGRKIVVRDRNRFHHFVNGSCSCGDYW 628          

Query:   46 VSFYAPIF------QSLTGKNLLKL-----GQQVHAQMALRGFEPDAYLG-------------------------------AKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHN-FASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVR--XTQNNLVAWNTMITAYASHGR---GSEAVSTFEDMIVA 1044
            ++FYA +        + T  ++LKL     G+ +H+Q    GF+ D Y+                                  M+  YA   +LD+A  +F  +     + +N +I  YT +G   E + ++ RM     K +  T   VL  C +L  +  G+ VH      G++ +++VGT+L++MY KC  + DAR +FDK+  +DV +WN++I                                GY  +G +++AL LF  M +    + P  +T + +L AC HS  +  G  I N      G+E  +     ++ +  + G +    Q +E V+    + + V W T++ A   HG+   G + V    D  +A
Sbjct:  113 LNFYAQMLTQGVEPNAFTFSSILKLCPIEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLKAKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIV-------------------------------GYAMHGFSQEALQLFKSMCRMG--LHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHV---EQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLA 457          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIV---SWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNF 828
            L+ G+ VH+ +   G + + ++G  +V MY+    L+ A  +F ++++   + +NS+I  Y +HGFS+E ++++  M  +GL   N T+  +L  C     +  G    + +  + G+E  +     ++N+  +   +  A  L   M +  D   W  L+      G+I L E +   +  +N+    ++  + + Y   G  +    L    + KDS VK          P C   +++E   K+H F
Sbjct:  272 LESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIVGYAMHGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARL--RTMMKDSGVKKE--------PGC---SSIEVNNKVHEF 508          

Query:  166 KMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            K+   YAS   LD +VA+F R  NPS   + +II  + L G  E+ +  Y +M   G++ + FT+  +LK C     I  GK +H  ++K+G +SD+YV T L+++Y +  D+  A++LFD M  + + S  A++  Y K GE+  A  LF  M  R+ V W  MI GYTQNG+  +AL LF  MLK  +K KPN VT++SVL AC    ALE GR +H++    G++ NV + TAL+ MY+KCGSL DAR  F+++     ++VAWN+MI  YA  G   EA+  F+ M   G+ P NITF G+LS C HSG V  G   F+ MK  Y +EP +EHY C+V+LLGRAG + +A +L+  M ++  P +WG +L ACR H  + + E     L      NSG Y++LSNIYA  G W  V  LR ++K  GVKK PGCS  EVN K H FL G  +HP+ KEIY  +L+E+   +K+ GY P T  VLHD+ E EKE SL  HSEKLAIAFGL+NT PG  +++ KNLR+C DCH  TKLIS+I  R+I+VRD NRFHHF +G+CSCGDYW
Sbjct:   14 KLQRSYASLGRLDYSVALFGRTQNPSVFFWTAIIHGHALRGLHEQALNFYAQMLTQGVEPNAFTFSSILKLCP----IEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLK--AKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKI--DDKDVVAWNSMIVGYAMXGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARLRTMMKDSGVKKEPGCSSIEVNNKVHEFLAGGLNHPKRKEIY-MMLEEINGWLKSHGYTPQTDIVLHDIGETEKERSLEVHSEKLAIAFGLINTQPGTTIKIVKNLRVCADCHEVTKLISKITGRKIVVRDRNRFHHFVNGSCSCGDYW 575          

Query:   46 VSFYAPIF------QSLTGKNLLKL-----GQQVHAQMALRGFEPDAYLG-------------------------------AKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHN-FASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVR--XTQNNLVAWNTMITAYASHGR---GSEAVSTFEDMIVA 1044
            ++FYA +        + T  ++LKL     G+ +H+Q    GF+ D Y+                                  M+  YA   +LD+A  +F  +     + +N +I  YT +G   E + ++ RM     K +  T   VL  C +L  +  G+ VH      G++ +++VGT+L++MY KC  + DAR +FDK+  +DV +WN++I                                GY   G +++AL LF  M +    + P  +T + +L AC HS  +  G  I N      G+E  +     ++ +  + G +    Q +E V+    + + V W T++ A   HG+   G + V    D  +A
Sbjct:   60 LNFYAQMLTQGVEPNAFTFSSILKLCPIEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLKAKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIV-------------------------------GYAMXGFSQEALQLFKSMCRMG--LHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHV---EQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLA 404          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIV---SWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNF 828
            L+ G+ VH+ +   G + + ++G  +V MY+    L+ A  +F ++++   + +NS+I  Y + GFS+E ++++  M  +GL   N T+  +L  C     +  G    + +  + G+E  +     ++N+  +   +  A  L   M +  D   W  L+      G+I L E +   +  +N+    ++  + + Y   G  +    L    + KDS VK          P C   +++E   K+H F
Sbjct:  219 LESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIVGYAMXGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARL--RTMMKDSGVKKE--------PGC---SSIEVNNKVHEF 455          

Query:  229 VNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            V+  +   +NS+I      G S E +  +  M  L LK +  T+P  +K C+ L  +  G+  H  +L  G E D++V ++L++MY KC ++ DAR LFD+++ R++ SW ++I GY+++ +   A  +F  M  R+++SW ++I+ Y QNG++ +++ +F  M+K D ++  N VT+ +VL ACAHS +   G+ IH+   ++GLESNV + T+++ MY KCG +  AR+ F+R+R  + N+ +W+ M+  Y  HG   EA+  F +M +AGV+P+ ITF  +L+ CSH+GL++ G  +F  M   + VEPGVEHY C+VDLLGRAG L EA DLI  M ++    +WGA+L ACR H N+++ EI+AR LF L+P+N G YV+LSNIYA+AG W++V+ +R+L+K  G+ K PG S  ++ G+ H+FL GD  HPQ ++IYE+ L++L  K++  GYVPD + VLHDV  EEKE  L  HSEKLA+AFG++NT PG  + + KNLR+CGDCHTA K IS+I +REI+VRD  RFHHF+DG CSCGDYW
Sbjct:   36 VDKTNVFSWNSVIAELARSGDSVEALRAFSSMRKLSLKPNRSTFPCAIKSCSALLDLHSGRQAHQQALIFGFEPDLFVSSALVDMYSKCGELRDARTLFDEISHRNIVSWTSMITGYVQNDDAHRALRVFDGMAERDVISWNSIIAVYAQNGMSTESMEIFHRMVK-DGEINYNAVTLSAVLLACAHSGSQRLGKCIHDQVIKMGLESNVFVGTSIIDMYCKCGKVEMARKAFDRMR--EKNVKSWSAMVAGYGMHGHAKEALEVFYEMNMAGVKPNYITFVSVLAACSHAGLLEEGWHWFKAMSHEFDVEPGVEHYGCMVDLLGRAGYLKEAFDLIKGMKLRPDFVVWGALLGACRMHKNVDLGEISARKLFELDPKNCGYYVLLSNIYADAGRWEDVERMRILMKNSGLVKPPGFSLVDIKGRVHVFLVGDREHPQHEKIYEY-LEKLSMKLQEVGYVPDMTSVLHDVGHEEKEMVLRVHSEKLAVAFGIMNTVPGTTIHIIKNLRVCGDCHTAIKFISKIVDREIVVRDSKRFHHFRDGLCSCGDYW 581          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYAS-------------------------------SDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLG-LKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERG-RKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASH 996
            L  G+Q H Q  + GFEPD ++ + +V MY+                                +DD   A+ +F  +     + +NSII  Y  +G S E+MEI+ RM   G +  +  T   VL  CA      +GKC+H   +K+GLES+++VGTS+I+MY KC  +  AR+ FD+M  ++V SW+A++A                               GY  +G A++AL +F EM    + VKPN++T +SVL AC+H+  LE G       +    +E  V     ++ +  + G L +A    + ++  + + V W  ++ A   H
Sbjct:   92 LHSGRQAHQQALIFGFEPDLFVSSALVDMYSKCGELRDARTLFDEISHRNIVSWTSMITGYVQNDDAHRALRVFDGMAERDVISWNSIIAVYAQNGMSTESMEIFHRMVKDGEINYNAVTLSAVLLACAHSGSQRLGKCIHDQVIKMGLESNVFVGTSIIDMYCKCGKVEMARKAFDRMREKNVKSWSAMVA-------------------------------GYGMHGHAKEALEVFYEM--NMAGVKPNYITFVSVLAACSHAGLLEEGWHWFKAMSHEFDVEPGVEHYGCMVDLLGRAGYLKEAFDLIKGMK-LRPDFVVWGALLGACRMH 391          

Query:   97 KLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRI-----WIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAE 609
            +LG+ +H Q+   G E + ++G  ++ MY     ++ A   F R+   +   +++++  Y +HG ++E +E++  M+  G+K +  T+  VL  C+    +     W     H   ++ G+E   + G  ++++  +   + +A  L   M +R D   W AL+        + L E
Sbjct:  226 RLGKCIHDQVIKMGLESNVFVGTSIIDMYCKCGKVEMARKAFDRMREKNVKSWSAMVAGYGMHGHAKEALEVFYEMNMAGVKPNYITFVSVLAACSHAGLLEEGWHWFKAMSHEFDVEPGVE---HYG-CMVDLLGRAGYLKEAFDLIKGMKLRPDFVVWGALLGACRMHKNVDLGE 398          

Query:   88 NLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVK--------------------------------CC---DMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            N L    Q+HAQ+ L     ++ +  ++++   S   LD A++IF   ++P+  ++N++IR    +   E ++  +  M  L ++ D  T PFVLK  A L  + +G+C+HG  +K+GLE D +V  SL++MYVK                                CC   D+S A  LF+ M  R+  SWN+LI G++++G++  A +LF +MP +N+VSWT MI+G++QNG  E+AL +F  ML++   V+PN +T++S L AC    AL+ G +IHN+ S  G + N  I TAL+ MYAKCG++  A + F  V     +L+ W+ MI  +A HG   +A+  F  M  AG+ PD + F  +L+ CSHSG VD GL +F+ M+  YS+EP ++HY  +VDLLGRAGRL EA   I  MP+     IWGA+  ACR H N+E+AE+ A  L  LEP++ G+YV LSN+YA  G W++V+ +R L+K +GV+K+PG S+ EV G+ H F+ GD +H +A+EI    L+E+    K  GY+P+T++VLH++ EEEKE +L +HSEKLA+AFGL++T+PG  +R+ KNLR+CGDCH+  K  S++  REII+RD+ RFHHFKDG CSCGDYW
Sbjct:   51 NTLPQLHQIHAQIFLHNLFSNSRVVTQLISSSCSLKSLDYALSIFRCFDHPNLFVFNALIRGLAENSRFEGSVSHFVLMLRLSIRPDRLTLPFVLKSVAALVDVGLGRCLHGGVMKLGLEFDSFVRVSLVDMYVKIGELGFGLQLFDESPQRNKAESILLWNVLINGCCKVGDLSKAASLFEAMPERNAGSWNSLINGFVRNGDLDRARELFVQMPEKNVVSWTTMINGFSQNGDHEKALSMFWRMLEEG--VRPNDLTVVSALLACTKIGALQVGERIHNYLSSNGFQLNRGIGTALVDMYAKCGNIKSASRVF--VETKGKDLLTWSVMIWGWAIHGCFDQALQCFVKMKSAGINPDEVIFLAILTACSHSGNVDQGLNFFESMRLDYSIEPTMKHYTLIVDLLGRAGRLDEALSFIQSMPINPDFVIWGALFCACRAHKNIEMAELTAEKLLQLEPKHPGSYVFLSNVYAAVGRWEDVERVRTLMKNRGVEKDPGWSYIEVEGQVHSFVAGDHAHVRAEEI-SLKLEEITASAKQEGYMPETAWVLHNIEEEEKEDALGSHSEKLALAFGLISTAPGSTIRIVKNLRVCGDCHSMMKYASKLSRREIILRDIKRFHHFKDGTCSCGDYW 677          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNI---------------------------------------VSWTAMISGYTQNGLAEQALFLFDEMLKKD-----------------------------SKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +  + ++   ++ L+ G++VH  +  RGFE D  +G  + +MY     L++A  +F R+     + +N+II  Y+ +G   E + ++  M   G+K ++ T   V+  CA L  +  GK +H  +++ G+ESD+ V   L+NMY KC +++ A +LF++M +RDV+SWNA+I GY  + +   A   F +M  R I                                       V   A+++ Y + G    A  LF+ M KK+                               +KP+   I+SVLPACAH  ALE+G++IH +  R G ESNV + T L+ +YAKCG++  A++ FER+   + ++V+W TMI AY  HG G +A++ F  M   G + D+I FT +L+ CSH+GLVD GL+YF  MK  Y + P +EHYAC+VDLLGRAG L EA  +I  M ++   ++WGA+L ACR H N+E+ E AA+ LF L+P+N+G YV+LSNIYAEA  W++V  LR ++K +GVKK PGCS   V+     FL GD +HPQ+++IY  +L+ L ++++ AGYVP+T+  L DV EE KE+ L++HSEKLAI+FG++NTSPG+ +R+ KNLR+C DCH ATK IS+I  REIIVRD NRFHH K+G CSCGDYW
Sbjct:  123 FLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQVFDRMPKRDVVSWNAIIAGYSQNGQPYEALALFSEMQVNGIKPNSSTLVSVMPVCAHLLALEQGKQIHCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPIRDVASWNAIIGGYSLNSQHHEALAFFNRMQVRGIKPNSITMVSVLPACAHLFALEQGQQIHGYAIRSGFESNDVVGNALVNMYAKCGNVNSAYKLFERMPKKNVVAWNAIISGYSQHGHPHEALALFIEMQAQGIKPDSFAIVSVLPACAHFLALEQGKQIHGYTIRSGFESNVVVGTGLVDIYAKCGNVNTAQKLFERM--PEQDVVSWTTMILAYGIHGHGEDALALFSKMQETGTKLDHIAFTAILTACSHAGLVDQGLQYFQCMKSDYGLAPKLEHYACLVDLLGRAGHLDEANGIIKNMSLEPDANVWGALLGACRIHCNIELGEQAAKHLFELDPDNAGYYVLLSNIYAEAQRWEDVAKLRKMMKEKGVKKQPGCSVVAVHRDVQTFLVGDRTHPQSEQIYA-MLEILYEQMRKAGYVPNTNLALQDVEEEAKENILSSHSEKLAISFGIINTSPGIPIRIMKNLRVCSDCHNATKFISKIVGREIIVRDANRFHHVKNGFCSCGDYW 795          

Query:  241 STLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            + +++   I  Y  +GF  + + +Y +M   G+  D   +  V+K C   S +  G+ VH   +  G ESD+ VGT+L +MY KC  + +AR+                               +F +MP R++VSW A+I+GY+QNG   +AL LF EM  + + +KPN  T++SV+P CAH  ALE+G++IH +A R G+ES+V +   L+ MYAKCG++  A + FER+     ++ +WN +I  Y+ + +  EA++ F  M V G++P++IT   +L  C+H   ++ G +   Y  R       V   A +V++  + G +  A  L  +MP +     W A++S   +H
Sbjct:   84 NAVVWKETIIGYVKNGFWNKALRLYYQMQRTGINPDKLVFLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQ-------------------------------VFDRMPKRDVVSWNAIIAGYSQNGQPYEALALFSEM--QVNGIKPNSSTLVSVMPVCAHLLALEQGKQIHCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPI--RDVASWNAIIGGYSLNSQHHEALAFFNRMQVRGIKPNSITMVSVLPACAHLFALEQGQQIHGYAIRSGFESNDVVGNA-LVNMYAKCGNVNSAYKLFERMP-KKNVVAWNAIISGYSQH 401          

Query:  637 NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACV----VDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAML---SACRKHH 1308
            N V W   I GY +NG   +AL L+ +M +  + + P+ +  +SV+ AC   + L+ GRK+H      G ES+V + TAL +MY KCGSL +ARQ F+R+   + ++V+WN +I  Y+ +G+  EA++ F +M V G++P++ T   ++  C+H   ++ G +        Y++  G+E    V    V++  + G +  A  L  +MP++   S W A++   S   +HH
Sbjct:   84 NAVVWKETIIGYVKNGFWNKALRLYYQMQR--TGINPDKLVFLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQVFDRM--PKRDVVSWNAIIAGYSQNGQPYEALALFSEMQVNGIKPNSSTLVSVMPVCAHLLALEQGKQI-----HCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPIRDVAS-WNAIIGGYSLNSQHH 304          

Query:   82 GKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGK-------MPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            G N LK  + VHA +   G + D+YL  K++    +  + + +  IFH+   P+  L+N++I    L+   +E++EIY  M   GL  D+FT+PF+LK CA L    +G  +HGL +K G ESD +V TSL+++Y KC  + +A ++FD +  ++V++W A+I+GY+  G+   A D+F +       M  ++IVSW++MI GY  NGL ++AL LF +ML +    +P+   ++ VL ACA   ALE G    N   R     N  + TAL+ MYAKCG +  A + F  +R  + ++V WN  I+  A  G    A   F  M  +G++PD  TF GLL  C+H+GLVD G +YF+ M+RV+++ P +EHY C+VDLLGRAG L EA  L+  MPM+A   +WGA+L  CR H + ++ E   + L  LEP NSGNYV+LSNIY+ +  W++   +R ++  +G+KK PG SW EV+G  H FL GDTSHP +++IY   L EL K +KA+GYVP T +VL D+ EEEKEH +  HSEKLAIAFGL++T+P   +RV KNLR+CGDCH A K ISR   REIIVRD NRFH F DG+CSC DYW
Sbjct:   19 GFNSLKHLKHVHAALLRLGLDEDSYLLNKVLRFSFNFGNTNYSHRIFHQTKEPNIFLFNTMIHGLVLNDSFQESIEIYHSMRKEGLSPDSFTFPFLLKACARLLDSKLGIKLHGLVVKAGCESDAFVNTSLVSLYGKCGFIDNAFKVFDDIPEKNVAAWTAIISGYIGVGKCREAIDMFRRACSVFDGMLEKDIVSWSSMIQGYASNGLPKEALDLFFKMLNEG--FRPDCYAMVGVLCACARLGALELGNWASNLMDRNEFLGNPVLGTALIDMYAKCGRMDSAWEVFRGMR--KKDIVVWNAAISGLAMSGHVKAAFGLFGQMEKSGIEPDGNTFVGLLCACTHAGLVDEGRQYFNSMERVFTLTPEIEHYGCMVDLLGRAGFLDEAHQLVKSMPMEANAIVWGALLGGCRLHRDTQLVEGVLKQLIALEPSNSGNYVLLSNIYSASHKWEDAAKIRSIMSERGIKKVPGYSWIEVDGVVHEFLVGDTSHPLSEKIYA-KLGELVKDLKASGYVPTTDYVLFDIEEEEKEHFIGCHSEKLAIAFGLISTAPNDKIRVVKNLRVCGDCHEAIKHISRFTGREIIVRDNNRFHCFNDGSCSCKDYW 619          

Query:   70 QSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM-----------------------------------HCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            ++  G + LK  +QVH   ++ GF+ D+++ + +V MY   + +  A  +F R+  P  + +++++ AY   G  +E   ++  M                                   H  G + D  T   VL    +L  + +G  +HG  +K GL SD  V ++LI+MY KC   S+  ++FD+M   DV S NA I G  ++G++  +  LF ++  +    N+VSWT+MI+  +QNG   +AL LF EM  + + VKPN VTI  +LPAC + AAL  G+  H F+ R G+ ++V + +AL+ MYAKCG +  +R CF+ +     NLV WN +I  YA HG+  EA+  F+ M  +G +PD I+FT +LS CS SGL + G  YF+ M   Y +E  VEHYAC+V LL RAG+L +A  +I +MP+     +WGA+LS+CR H+N+ + E+AA  LF LEP N GNY++LSNIYA  GMW EV+ +R ++K +G++KNPGCSW EV  K H+ L GD SHPQ  +I E  LD+L  ++K  GY P+ +FVL DV E++KE  L  HSEKLA+ FGLLNT PG  L+V KNLRICGDCH   K IS    REI VRD NRFHHFK+G CSCGDYW
Sbjct:  122 KACAGLSALKPARQVHGIASVSGFDSDSFVQSSLVHMYIKCNQIRDAHRVFDRMFEPDVVSWSALVAAYARQGCVDEAKRLFSEMGDSGVQPNLISWNGMIAGFNHSGLYSEAVLMFLDMHLRGFEPDGTTISSVLPAVGDLEDLVMGILIHGYVIKQGLVSDKCVSSALIDMYGKCSCTSEMSQVFDQMDHMDVGSCNAFIFGLSRNGQVESSLRLFRQLKDQGMELNVVSWTSMIACCSQNGRDIEALELFREM--QIAGVKPNSVTIPCLLPACGNIAALMHGKAAHCFSLRRGISTDVYVGSALIDMYAKCGRIQASRICFDGI--PTKNLVCWNAVIAGYAMHGKAKEAMEIFDLMQRSGQKPDIISFTCVLSACSQSGLTEEGSYYFNSMSSKYGIEARVEHYACMVTLLSRAGKLEQAYAMIRRMPVNPDACVWGALLSSCRVHNNVSLGEVAAEKLFELEPSNPGNYILLSNIYASKGMWNEVNRVRDMMKNKGLRKNPGCSWIEVKNKVHMLLAGDKSHPQMTQIIE-KLDKLSMEMKKLGYFPEINFVLQDVEEQDKEQILCGHSEKLAVVFGLLNTPPGYPLQVIKNLRICGDCHVVIKFISSFERREIFVRDTNRFHHFKEGACSCGDYW 758          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERV---------------------------------RXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH----HNLEIAEIAARS 1341
            +Q HA +   G   D +L  K+++ YA++     A  +   V  P+   ++++I A++        +  + +M   GL  DN   P  +K CA LS +   + VHG++   G +SD +V +SL++MY+KC  + DA R+FD+M   DV SW+AL+A Y + G +  A+ LF +M       N++SW  MI+G+  +GL  +A+ +F +M  +    +P+  TI SVLPA      L  G  IH +  + GL S+  + +AL+ MY KC    +  Q F+++                                 +  + N+V+W +MI   + +GR  EA+  F +M +AGV+P+++T   LL  C +   +  G     +  R   +   V   + ++D+  + GR+  ++     +P +     W A+++    H      +EI ++  RS
Sbjct:   33 RQAHAHILKTGLFNDTHLATKLLSHYANNMCFADATLVLDLVPEPNVFSFSTLIYAFSKFHQFHHALSTFSQMLTRGLMPDNRVLPSAVKACAGLSALKPARQVHGIASVSGFDSDSFVQSSLVHMYIKCNQIRDAHRVFDRMFEPDVVSWSALVAAYARQGCVDEAKRLFSEMGDSGVQPNLISWNGMIAGFNHSGLYSEAVLMFLDMHLRG--FEPDGTTISSVLPAVGDLEDLVMGILIHGYVIKQGLVSDKCVSSALIDMYGKCSCTSEMSQVFDQMDHMDVGSCNAFIFGLSRNGQVESSLRLFRQLKDQGMELNVVSWTSMIACCSQNGRDIEALELFREMQIAGVKPNSVTIPCLLPACGNIAALMHGKAAHCFSLR-RGISTDVYVGSALIDMYAKCGRIQASRICFDGIPTK-NLVCWNAVIAGYAMHGKAKEAMEIFDLMQRS 481          

Query:  334 GLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            G+K + FT   V+K CA ++ +  GK  H   +K+G ESD+ V T+L++MY +C  + DA  +FDKM+ R   +WNA+I G+ ++ ++  A  LF +M  R++VSWTA+I+GY QNG  +++L +F++M K  + +K +   + SVL ACA  AALE GR+ H +  + G   ++ + +AL+ MYAK GS+ DA Q F+++   Q N V+WN++IT  A HGRG++AV  FE M+ AG++P+ I+F G+LS CSH+GLV+ G  YF+ M + Y + P V HY C++DLLGRAG L EA++ I  MP++   S+WGA+L ACR H N E+A+  A  L  +E + +G YV+LSNIYA AG W +   +R L+K +GV K PG SW EV    H F+ G+TSHPQ KEI+EF L+ L +K+KAAGYVP+ +FVL DV ++EKE SL+ HSEKLAIAFG++NT+PG  +RV KNLR+CGDCHT  K IS  + R+I+VRD NRFHHFKDG CSCGDYW
Sbjct:    5 GVKPNQFTLSTVVKACASIASLEQGKQAHNYIIKMGFESDVVVQTALVHMYARCGSLEDAGHVFDKMSERSTRTWNAMITGHAQNRDMKKALKLFYEMSERDVVSWTAVIAGYAQNGYGDESLNVFNQMRK--TGMKSDRFIMGSVLSACADLAALELGRQFHAYVVQSGFALDIVVGSALVDMYAKSGSMEDACQVFDKM--PQRNEVSWNSIITGCAQHGRGNDAVLLFEQMLQAGIKPNEISFVGVLSACSHTGLVNEGRGYFNLMTQNYGIVPDVSHYTCMIDLLGRAGCLDEAENFINGMPVEPDVSVWGALLGACRIHGNTELAKRIAEHLLGMEVQIAGIYVLLSNIYAAAGQWDDAAKVRKLMKDRGVMKQPGYSWIEVKTIMHAFVAGETSHPQLKEIHEF-LESLSRKMKAAGYVPNKNFVLQDVEDDEKELSLSHHSEKLAIAFGIINTNPGTTIRVAKNLRVCGDCHTVIKFISLNFTRKIVVRDANRFHHFKDGRCSCGDYW 514          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYN-------------------------------SIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASR-IGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQ 1053
            L+ G+Q H  +   GFE D  +   +V MYA    L+ A  +F +++  ST  +N                               ++I  Y  +G+ +E++ ++ +M   G+K D F    VL  CA+L+ + +G+  H   ++ G   D+ VG++L++MY K   M DA ++FDKM  R+  SWN++                               I+G  Q+G    A+ LF++ML+  + +KPN ++ + VL AC+H+  +  GR   N  ++  G+  +VS  T ++ +  + G  LD  + F      + ++  W  ++ A   HG    A    E ++   VQ
Sbjct:   26 LEQGKQAHNYIIKMGFESDVVVQTALVHMYARCGSLEDAGHVFDKMSERSTRTWNAMITGHAQNRDMKKALKLFYEMSERDVVSWTAVIAGYAQNGYGDESLNVFNQMRKTGMKSDRFIMGSVLSACADLAALELGRQFHAYVVQSGFALDIVVGSALVDMYAKSGSMEDACQVFDKMPQRNEVSWNSI-------------------------------ITGCAQHGRGNDAVLLFEQMLQ--AGIKPNEISFVGVLSACSHTGLVNEGRGYFNLMTQNYGIVPDVSHYTCMIDLLGRAG-CLDEAENFINGMPVEPDVSVWGALLGACRIHGNTELAKRIAEHLLGMEVQ 343          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGL-SLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIV---SWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKP--NWVTIMSVLPA-CAHSAALERGRKIHNF 828
            L+LG+Q HA +   GF  D  +G+ +V MYA S  ++ A  +F ++   + + +NSII     HG   + + ++ +M   G+K +  ++  VL  C+    +  G+    L +   G+  D+   T +I++  +   + +A    + M V  DVS W AL+      G   LA+ +   + G  +     +  + + Y   G  + A  +   M  +    +P  +W+ + +++ A  A   +  + ++IH F
Sbjct:  158 LELGRQFHAYVVQSGFALDIVVGSALVDMYAKSGSMEDACQVFDKMPQRNEVSWNSIITGCAQHGRGNDAVLLFEQMLQAGIKPNEISFVGVLSACSHTGLVNEGRGYFNLMTQNYGIVPDVSHYTCMIDLLGRAGCLDEAENFINGMPVEPDVSVWGALLGACRIHGNTELAKRIAEHLLGMEVQIAGIYVLLSNIYAAAGQWDDAAKVRKLMKDRGVMKQPGYSWIEVKTIMHAFVAGETSHPQLKEIHEF 410          

Query:  304 MEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +E Y RMH LGL  DNFT PFVLK CA+LSR+ +G+CVHG  L+VGLE D YVG SLI+MYVKC  + DAR+LFDKM VRD++SWNALIAGYMK+GEI +AEDLF +M  RNIVSWTAMISGYTQNG AEQAL LFDEML+  S++KPNWVTI+SVLPACA SAALERGR+IH+FA+ IGL  N S+QTAL  MYAKC SL++AR CF+ +     NL+AWNTMITAYASHG G EAVS FE+M+ AGVQPD +TF GLLSGCSHSGL+D GL +F+ M  ++SVEP VEHYACVVDLLGRAGRL EAK+LI +MPMQAGPS+WGA+L+ACR H NLEIAE+AAR LF+LEP+NSGNYV+LSN+YAEAGMW+EV  LR LLK QG+KK+PGCSW E+NGK+HLF+G D SHPQAKEIY+F L+ LP+KIK AGY+PDTSFVLHD+SEEEKE++LTTHSEKLAIAFGLLNT PGVVLRVTKNLRICGDCH ATK IS+IYEREIIVRDLNRFH FKDG+CSCGDYW
Sbjct:   92 LEAYARMHFLGLLGDNFTLPFVLKSCADLSRVCMGRCVHGQGLRVGLEGDFYVGASLIDMYVKCGVIGDARKLFDKMIVRDMASWNALIAGYMKEGEIGVAEDLFERMEHRNIVSWTAMISGYTQNGFAEQALGLFDEMLQDGSEMKPNWVTIVSVLPACAQSAALERGRRIHDFANGIGLHLNSSVQTALAGMYAKCYSLVEARCCFDMIAQNGKNLIAWNTMITAYASHGCGVEAVSIFENMLRAGVQPDAVTFMGLLSGCSHSGLIDAGLNHFNDMGTIHSVEPRVEHYACVVDLLGRAGRLVEAKELISQMPMQAGPSVWGALLAACRSHRNLEIAELAARRLFVLEPDNSGNYVLLSNLYAEAGMWEEVKKLRALLKYQGMKKSPGCSWIEINGKSHLFMGADKSHPQAKEIYKF-LEALPEKIKMAGYIPDTSFVLHDISEEEKEYNLTTHSEKLAIAFGLLNTRPGVVLRVTKNLRICGDCHAATKFISKIYEREIIVRDLNRFHCFKDGSCSCGDYW 615          

Query:  140 SNPMHISAPRWSQCMQAQMIXXXXXXXXXXXXXHQRFCIIRSFGRIRYMGSLRKP 304
            SNPMH S P+W QCM A  I             H   CIIR FG I  MG L+KP
Sbjct:    3 SNPMHSSPPKWWQCMPAPGILIPLWSFLIGLITHLLCCIIRLFGLILDMGFLKKP 57          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYAS-------------------------------SDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLG--LKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI-GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDN 1062
            + +S    + + +G+ VH Q    G E D Y+GA ++ MY                                   ++  A  +F R+ + + + + ++I  YT +GF+E+ + ++  M   G  +K +  T   VL  CA+ + +  G+ +H  +  +GL  +  V T+L  MY KC  + +AR  FD +                ++G+  +A              W  MI+ Y  +G   +A+ +F+ ML+  + V+P+ VT M +L  C+HS  ++ G    N    I  +E  V     ++ +  + G L++A++   ++   Q     W  ++ A  SH     A      + V  ++PDN
Sbjct:  113 VLKSCADLSRVCMGRCVHGQGLRVGLEGDFYVGASLIDMYVKCGVIGDARKLFDKMIVRDMASWNALIAGYMKEGEIGVAEDLFERMEHRNIVSWTAMISGYTQNGFAEQALGLFDEMLQDGSEMKPNWVTIVSVLPACAQSAALERGRRIHDFANGIGLHLNSSVQTALAGMYAKCYSLVEARCCFDMIA---------------QNGKNLIA--------------WNTMITAYASHGCGVEAVSIFENMLR--AGVQPDAVTFMGLLSGCSHSGLIDAGLNHFNDMGTIHSVEPRVEHYACVVDLLGRAGRLVEAKELISQM-PMQAGPSVWGALLAACRSHRNLEIAELAARRLFV--LEPDN 445          

Query:  229 VNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            V+  +   +NS+I      G S E +  +  M  L LK +  T+P  +K C+ L  +  G+  H  +L  G E D++V ++L++MY KC ++ DAR LFD+++ R++ SW ++I GY+++ +   A  +F  M  R+++SW ++I+ Y QNG++ +++ +F  M+K D ++  N VT+ +VL ACAHS +   G+ IH+   ++GLESNV + T+++ MY KCG +  AR+ F+R+R  + N+ +W+ M+  Y  HG   EA+  F +M +AGV+P+ ITF  +L+ CSH+GL++ G  +F  M   + VEPGVEHY C+VDLLGRAG L EA DLI  M ++    +WGA+L ACR H N+++ EI+AR LF L+P+N G YV+LSNIYA+AG W++V+ +R+L+K  G+ K PG S  ++ G+ H+FL GD  HPQ ++IYE+ L++L  K++  GYVPD + VLHDV  EEKE  L  HSEKLA+AFG++NT PG  + + KNLR+CGDCHTA K IS+I +REI+VRD  RFHHF+DG CSCGDYW
Sbjct:   36 VDKTNVFSWNSVIAELARSGDSVEALRAFSSMRKLSLKPNRSTFPCAIKSCSALLDLHSGRQAHQQALIFGFEPDLFVSSALVDMYSKCGELRDARTLFDEISHRNIVSWTSMITGYVQNDDAHRALRVFDGMAERDVISWNSIIAVYAQNGMSTESMEIFHRMVK-DGEINYNAVTLSAVLLACAHSGSQRLGKCIHDQVIKMGLESNVFVGTSIIDMYCKCGKVEMARKAFDRMR--EKNVKSWSAMVAGYGMHGHAKEALEVFYEMNMAGVKPNYITFVSVLAACSHAGLLEEGWHWFKAMSHEFDVEPGVEHYGCMVDLLGRAGYLKEAFDLIKGMKLRPDFVVWGALLGACRMHKNVDLGEISARKLFELDPKNCGYYVLLSNIYADAGRWEDVERMRILMKNSGLVKPPGFSLVDIKGRVHVFLVGDREHPQHEKIYEY-LEKLSMKLQEVGYVPDMTSVLHDVGHEEKEMVLRVHSEKLAVAFGIMNTVPGTTIHIIKNLRVCGDCHTAIKFISKIVDREIVVRDSKRFHHFRDGLCSCGDYW 581          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYAS-------------------------------SDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLG-LKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERG-RKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASH 996
            L  G+Q H Q  + GFEPD ++ + +V MY+                                +DD   A+ +F  +     + +NSII  Y  +G S E+MEI+ RM   G +  +  T   VL  CA      +GKC+H   +K+GLES+++VGTS+I+MY KC  +  AR+ FD+M  ++V SW+A++A                               GY  +G A++AL +F EM    + VKPN++T +SVL AC+H+  LE G       +    +E  V     ++ +  + G L +A    + ++  + + V W  ++ A   H
Sbjct:   92 LHSGRQAHQQALIFGFEPDLFVSSALVDMYSKCGELRDARTLFDEISHRNIVSWTSMITGYVQNDDAHRALRVFDGMAERDVISWNSIIAVYAQNGMSTESMEIFHRMVKDGEINYNAVTLSAVLLACAHSGSQRLGKCIHDQVIKMGLESNVFVGTSIIDMYCKCGKVEMARKAFDRMREKNVKSWSAMVA-------------------------------GYGMHGHAKEALEVFYEM--NMAGVKPNYITFVSVLAACSHAGLLEEGWHWFKAMSHEFDVEPGVEHYGCMVDLLGRAGYLKEAFDLIKGMK-LRPDFVVWGALLGACRMH 391          

Query:   97 KLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRI-----WIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAE 609
            +LG+ +H Q+   G E + ++G  ++ MY     ++ A   F R+   +   +++++  Y +HG ++E +E++  M+  G+K +  T+  VL  C+    +     W     H   ++ G+E   + G  ++++  +   + +A  L   M +R D   W AL+        + L E
Sbjct:  226 RLGKCIHDQVIKMGLESNVFVGTSIIDMYCKCGKVEMARKAFDRMREKNVKSWSAMVAGYGMHGHAKEALEVFYEMNMAGVKPNYITFVSVLAACSHAGLLEEGWHWFKAMSHEFDVEPGVE---HYG-CMVDLLGRAGYLKEAFDLIKGMKLRPDFVVWGALLGACRMHKNVDLGE 398          

Query:   34 DPRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLG-AKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAA-GYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +P+ +S + P       K L  L +QVHAQ+      P      A + A+      L  A  IFH + NP   LYNS+IRA +      E + +Y  M   GLK D+ TYPFV+K C E S  W G  VH   +K G E D Y+ +SLI++Y    D+  A++LF+  + RDV SWNA+I GY+K  E+  A  +F +M  R+++SW  MI+GY   G   +AL LFD+M  +   VKP   T++S+L ACAH  AL++G  +H + +   +E N  + TAL+ MYAKCG +  A Q F  +     +++AWNT+I   A HG   EA   F++M  AGV+P++ITF  +LS CSH+G+VD G K  D M   Y +EP VEHY CV+DLL RAG L EA +LI  MPM+  PS  GA+L  CR H N E+ E+  + L  L+P +SG Y++LSNIYA A  W +   +R L+K  G+ K PG S  E+ G  H F+ GD SHP++ +IYE  L+E+  ++K+A GY  DT  VL D+ EE+KEH+L  HSEKLAIA+GLL+      +R+ KNLR+C DCH   KLIS++Y REIIVRD NRFHHF+DG CSC D+W
Sbjct:   67 NPQILSLFNPC------KTLRHL-KQVHAQIITHHNSPFQLSALASLSALSPFPTFLAYAKTIFHHLQNPPPSLYNSLIRALSSSKTPLEALPLYHTMLQSGLKPDHMTYPFVIKACNESSVTWFGLLVHTHVVKSGFECDSYIVSSLIHLYANGKDLGAAKQLFNLCSARDVVSWNAMIDGYVKHVEMGHARMVFDRMVCRDVISWNTMINGYAICGKPNEALALFDQM--RAVGVKPTEATVVSLLSACAHLGALDKGLHLHTYINDNRIEVNSIVGTALVDMYAKCGKISLATQVFNAME--SKDVLAWNTIIAGMAIHGNVKEAQQLFKEMKEAGVEPNDITFVAILSACSHAGMVDEGQKLLDCMSSSYGIEPKVEHYGCVIDLLARAGFLEEAMELIGTMPMEPNPSALGALLGGCRIHGNFELGEMVGKRLINLQPCHSGRYILLSNIYAAAKKWDDARKVRNLMKVNGISKVPGVSVIELKGMVHRFVAGDWSHPESNKIYE-KLNEIHTRLKSAIGYSADTGNVLLDMEEEDKEHALAVHSEKLAIAYGLLHLDSKEAIRIVKNLRVCRDCHHVIKLISKVYGREIIVRDRNRFHHFEDGECSCLDFW 671          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVG-LESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIA--GYMKDGE----------ICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +  +F++ +     ++G+ V+  M   GFE ++ +   ++ M+     +D A   F  +      ++N ++  YT  G  ++ + ++ +M   G+K ++ T    +  C  LS +  G+ +HG  +KV  L+SD+ VG SL++ Y KC  +  ARR F  +   D+ SWNA++A  G+ + G+          + +A  +F ++  R++V W ++IS   Q+G +  AL L  EM    S V+ N VT++S LPAC+  AAL +G++IH F  R GL++   I  +L+ MY +CGS+  +R+ F+ +   Q +LV+WN MI+ Y  HG G +AV+ F+     G++P++ITFT LLS CSHSGL++ G KYF  MK  Y+++P VE YAC+VDLL RAG+  E  + I KMP +   ++WG++L ACR H N ++AE AAR LF LEP++SGNYV+++NIY+ AG W++   +R L+K +GV K PGCSW EV  K H F+ GDTSHP  ++I    ++ L   IK  GYVPDT+FVL DV E+EKE SL  HSEK+A+AFGL++T+ G  LR+ KNLR+CGDCH+ATK IS++ +R+II+RD  RFHHF DG CSCGDYW
Sbjct:  114 FPKVFKACSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKMVLEGVKPNSITIASAVSACTNLSLLRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIKQTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREM--NLSNVEVNTVTMVSALPACSKLAALRQGKEIHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLM--PQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMGLKPNHITFTNLLSACSHSGLIEEGWKYFKMMKTEYAMDPAVEQYACMVDLLSRAGQFNETLEFIEKMPFEPNAAVWGSLLGACRIHCNPDLAEYAARYLFELEPQSSGNYVLMANIYSAAGRWEDAAKIRCLMKERGVTKPPGCSWIEVKRKLHSFVVGDTSHPLMEQI-SAKMESLYFDIKEIGYVPDTNFVLQDVDEDEKEFSLCGHSEKIALAFGLISTTAGTPLRIIKNLRVCGDCHSATKFISKVEKRDIIMRDNYRFHHFVDGVCSCGDYW 729          

Query:   46 VSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI-GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTM--ITAYASHGRGSEAVSTFEDMIVAG------VQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENS-GNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKN 1470
            +  YA I Q       L+LG QVHAQ+ + G +   +LG++++ +Y  +  ++ A  +F +++  +   + +I+  Y   G  EET++++  M   G++ D+F +P V K C+EL    +GK V+   L +G E +  V  S+++M++KC  M  ARR F+++  +DV  WN +++GY   GE   A ++F KM          ++ G                       VKPN +TI S + AC + + L  GR+IH +  ++  L+S++ +  +L+  YAKC S+  AR+ F  ++  Q +LV+WN M  +T +  +G G  A+  F+ M +A          D + +  ++S C+ SG     L     M  + +VE         +    +   L + K+ I +  ++ G      +L++    +    +   +R +F L P+    ++ ++ ++Y   G   +  NL    +  G+K N
Sbjct:   10 IEIYASILQKCRKLYNLRLGFQVHAQLVVNGVDVCEFLGSRLLEVYCQTGCVEDARRMFDKMSERNVFSWTAIMEMYCGLGDYEETIKLFYLMVNEGVRPDHFVFPKVFKACSELKNYRVGKDVYDYMLSIGFEGNSCVKGSILDMFIKCGRMDIARRFFEEIEFKDVFMWNIMVSGYTSKGEFKKALNVFRKM----------VLEG-----------------------VKPNSITIASAVSACTNLSLLRHGREIHGYCIKVEELDSDLLVGNSLVDYYAKCRSVEVARRKFGMIK--QTDLVSWNAMLAVTGFTQYGDGKAALEFFQRMHIACSVFSELSTRDVVVWNSIISACAQSGRSVNALDLLREM-NLSNVEVNTVTMVSALPACSKLAALRQGKE-IHQFIIRCGLDTCNFILNSLIDMYGRCGSIQKSRRIFDLMPQRDLVSWNVMISVYGMHGFGMDAVNLFQQFRTMGLKPN 457          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSD--DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGE---ICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYA----KCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            LK   ++ +QM L GF  D +  ++++     S    LD ++ IF R+ N +  ++N+++RAY     +E+ + +Y  M    +  DN+TYP V++ CA     + GK +H   LKVG +SD+YV  +LINMY  C +M DAR+LFD+  V D  SWN+++AGY+K G+   +  A  LF +M  +++VSW+A+ISGY QNG+ E+AL +F EM     ++    V ++SVL ACAH + ++ G+ IH    R+G+ES V++Q AL+ MY+    KCG + +A + F  +   +  + +WN +I   A +G    ++  F +M   GV P+ ITF G+L  C H GLVD G  +F  M   + +EP V+HY C+VDLLGRAG L EA+ LI  MPM    + WGA+L AC+KH + E+ E   R L  L+P++ G +V+LSNI+A  G W++V  +R ++K QGV K PGCS  E NG  H FL GD +HP   ++ E +L+E+ K++K  GY PDT+ V  D+ EEEKE +L  HSEKLAIAFGLL  SP   +R+ KNLRIC DCHTA KLIS+ Y REI+VRD +RFH+FK+G CSC DYW
Sbjct:   42 LKQFNRILSQMILTGFISDTFAASRLLKFSTDSPFIGLDYSLQIFDRIENSNGFMWNTMMRAYIQSNSAEKALLLYKLMVKNNVGPDNYTYPLVVQACAVRLLEFGGKEIHDHVLKVGFDSDVYVQNTLINMYAVCGNMRDARKLFDESPVLDSVSWNSILAGYVKKGDMGQVMEAWKLFNEMDEKDMVSWSALISGYEQNGMYEEALVMFIEMNANGMRLDE--VVVVSVLSACAHLSIVKTGKMIHGLVIRMGIESYVNLQNALIHMYSDMYMKCGCVENALEVFNGME--EKGVSSWNALIIGLAVNGLVERSLDMFSEMKNNGVIPNEITFMGVLGACRHMGLVDEGRCHFASMIEKHGIEPNVKHYGCMVDLLGRAGLLNEAEKLIESMPMAPDVATWGALLGACKKHGDTEMGERVGRKLIELQPDHDGFHVLLSNIFASKGDWEDVLEVRGMMKQQGVVKTPGCSLIEANGVVHEFLAGDKTHPWINKV-EGMLNEMAKRLKMEGYAPDTNEVSLDIDEEEKETTLFRHSEKLAIAFGLLTISPPTPIRIMKNLRICNDCHTAAKLISKAYAREIVVRDRHRFHYFKEGACSCMDYW 640          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAG---------------YMKDGEIC-----------------LAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            Y  + ++      L   +++H          D+ +  K+  +Y S + +  A  +F  + NPS +L+N IIRAY  +G  +  +++Y  M  LG++ + +TYPFVLK C+ L  I  G  +H  +   GLESD++V T+L++ Y KC  + +A+RLF  M+ RDV +WNA+IAG                M++  IC                  A  +F  M  RN VSW+AMI GY  +   ++AL +F  M  + S + P+  T++ VLPAC+H AAL+ G   H +    G  ++  I  AL+ MY+KCG +  AR+ F R+   ++++V+WN MI  Y  HG G EA+  F D++  G++PD+ITF  LLS CSHSGLV  G  +FD M R +S+ P +EH  C+VD+LGRAG + EA   I  MP +    IW A+LSACR H N+E+ E  ++ +  L PE++GN+V+LSNIY+ AG W +  ++R+  K  G+KK PGCSW E+NG  H F+GGD SH Q  +I    L+EL  ++K  GY  + SFV  DV EEEKE  L  HSEKLAIAFG+LN   G  + VTKNLR+CGDCHTA K ++ I +REI VRD NRFHHFK+G C+CGD+W
Sbjct:   11 YLHLLEACIQSKSLTEAKKIHQHFLKNTSNADSSVLHKLTRLYLSCNQVVLARRLFDEIPNPSVILWNQIIRAYAWNGPFDGAIDLYHSMLHLGVRPNKYTYPFVLKACSGLLAIEDGVEIHSHAKMFGLESDVFVCTALVDFYAKCGILVEAQRLFSSMSHRDVVAWNAMIAGCSLYGLCDDAVQLIMQMQEEGICPNSSTIVGVLPTCQCLLYARKIFDVMGVRNEVSWSAMIGGYVASDCMKEALDIFRMM--QLSGIDPDLTTMLGVLPACSHLAALQHGFCSHGYLIVRGFATDTLICNALIDMYSKCGKISFAREVFNRM--DRHDIVSWNAMIIGYGIHGLGMEALGLFHDLLALGLKPDDITFICLLSSCSHSGLVMEGRLWFDAMSRDFSIVPRMEHCICMVDILGRAGLIDEAHHFIRNMPFEPDVRIWSALLSACRIHKNIELGEEVSKKIQSLGPESTGNFVLLSNIYSAAGRWDDAAHIRITQKDWGLKKIPGCSWIEINGIVHAFVGGDQSHLQLSQINR-KLEELLVEMKRLGYQAECSFVFQDVEEEEKEQILLYHSEKLAIAFGILNLKAGRPILVTKNLRVCGDCHTAIKFMTLITKREITVRDANRFHHFKNGTCNCGDFW 645          

Query:   37 PRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDA-YLGAKMVAMYASSDDLDSAVAIF-HRVNN-------PSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIA-------------------------------------GYMKDGEICL--AEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            P    FY  + Q  T    LKL   +H+ ++ RGF     +  A+++ +Y+   DL SA  +F HR ++       P++ L N+++RAY   G S E +++Y  M  +G+  +NFTYPFVLK CA       G+ VHG  ++ G  SD++V  +L++MY KC ++ DA  +FD+M +RDV  W A+I                                      G + DG + +  A  +F +M  RN +SW +M+SGYTQNG    AL LF++M  + S+  PN VT + ++ AC++  +   GRK+HNF     ++ + +++ A++ MY KCG L  A + F      + ++ +WN +I+ Y  HG G EA+  F  M V GV+P++ITFT +LS CSH+GL+D G K F  M ++ SV P ++HYAC+VD+LGRAG L EA  LI K+P +    +WGA+L ACR H N E+ EIAA +LF LEPE++G YV++SNIYA +  WKEV+ +R  +K++G+KK    S  E   + H F   D S P  +E+Y   ++ L  ++K  GYVPD S VLHDV  E+KEH L  HSEKLA+AFG++    G+ ++VTKNLR+C DCH A K IS IY R+IIVRD NRFHHF+ G CSCGDYW
Sbjct:   22 PSLHHFYDHLLQCCTSLTTLKL---IHSSLSTRGFLLHTPHFLARLIILYSKLGDLHSARTLFDHRHHHHHGHTQAPNSFLCNTMLRAYANAGRSYEAIDLYIYMQRMGVGVNNFTYPFVLKVCASELGAVFGEVVHGQVVRTGFGSDLFVEAALVDMYAKCGEIGDAHEVFDRMLIRDVVCWTAMITLYEQAERPLKALMLFRKMQEEGFLGDEITAISVASAVGQLGDGRMAISRARLVFDRMEERNGISWNSMLSGYTQNGRPTDALSLFNQM--QASECDPNPVTALIMVSACSYLGSKHLGRKLHNFVISSKMDIDTTLRNAIMDMYMKCGDLDTAVEMFNNCELGERDVSSWNVLISGYGVHGHGKEALELFSRMQVEGVEPNDITFTSILSACSHAGLIDEGRKCFADMTKL-SVRPEMKHYACMVDMLGRAGFLNEAFRLIKKIPSRPSDEVWGALLLACRIHGNTELGEIAANNLFQLEPEHTGYYVLMSNIYAASNKWKEVEMVRQNMKSRGLKKPAAFSVIEFGTEVHGFHTADQSSPYYREVYR-KVESLAIEMKMVGYVPDLSCVLHDVEPEDKEHLLNYHSEKLAVAFGIMKMDQGMPIQVTKNLRVCSDCHWAFKFISSIYGRKIIVRDGNRFHHFQGGRCSCGDYW 676          

Query:  148 DAYLGAKMVAMYASSDD--LDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMP-GRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            D +  +K+VA  A  D   L  A  +F+++ NP+T   NSIIR YT      + +  Y  M   GL  D FT+P + K C  L     GK +H  S K+G  SD Y+  +L+NMY  C  +  AR++FDKM  + V SW  +I  Y +      A  LF +M    N+  W  MI+G+ ++   E+AL LF+EM  + S VK + VT+ S+L AC H  ALE G+ +H +  +  +E +V++ TAL+ MYAKCGS+  A + F+ +   + +++ W  +I   A  G+G +A+  F +M ++ V+PD ITF G+L+ CSH+GLV+ G+ YF+ M   Y ++P +EHY C+VD+LGRAGR+AEA+DLI  MPM     +   +LSACR H NL +AE AA+ L  L+P+N G YV+LSNIY+    W+    +R L+  + +KK PGCS  EV G  H F+ GD SHPQ+ EIYE  LD++ +++K+AGYVPD S VL D+ E+EKE+ L+ HSEKLAIAFGLL+T+PG  +RV KNLR+C DCH+A K IS +Y REIIVRD NRFHHF  G+CSC D+W
Sbjct:    9 DPFSASKIVAFCALHDSGSLPYARLVFNQIPNPTTFTCNSIIRGYTNKNLPRQAILFYQLMMLQGLDPDRFTFPSLFKSCGVLCE---GKQLHCHSTKLGFASDAYIQNTLMNMYSNCGCLVSARKVFDKMVNKSVVSWATMIGAYAQWDLPHEAIKLFRRMEIASNLFCWNIMINGHVEDSDYEEALSLFNEM--QLSGVKGDKVTMASLLIACTHLGALELGKWLHVYIEKEKIEVDVALGTALVDMYAKCGSIESAMRVFQEM--PEKDVMTWTALIVGLAMCGQGLKALELFHEMQMSEVKPDAITFVGVLAACSHAGLVNEGIAYFNSMPNKYGIQPSIEHYGCMVDMLGRAGRIAEAEDLIQNMPMAPDYFVLVGLLSACRIHGNLVVAERAAQQLIELDPKNGGTYVLLSNIYSSMKNWEAAKKMRELMVERNIKKPPGCSAIEVGGVVHEFVKGDVSHPQSSEIYE-TLDDMMRRLKSAGYVPDKSEVLFDMDEKEKENELSLHSEKLAIAFGLLSTTPGTPIRVVKNLRVCSDCHSAMKFISEVYNREIIVRDRNRFHHFTKGSCSCRDFW 580          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMP----GRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            ++VH      GF  D  LG  ++ MY      + A  +F  +     + + S+   Y   G   E +  + +M   G + ++ T   +L  C +L  +  G+ VHG  ++ G+  +++V ++L+NMY  C  +  A+ +FD M+ RD  SWN LI  Y  + E      +FG+M     G N  SW A+I G  QNG  E+AL +   M  ++S  KPN +TI SVLPAC +  +L  G++IH +  R     +++  TAL+ MYAKCG L  +R+ F  +  T+ + V+WNTMI A + HG G EA+  F +M+ +GV+P+++TFTG+LSGCSHS LVD GL  FD M R +SVEP  +H++C+VD+L RAGRL EA + I KMP++     WGA+L  CR + N+E+  IAA  LF +E +N GNYV+LSNI   A +W E    R L++ +GV KNPGCSW +V  + H F+ GD S+ Q+ EIY F LD + +K++ AGY+P+T FVL DV +EEKE  L  HSEKLA+AFG+LN +    +RV KNLRICGDCH A K +++I   +IIVRD  RFHHF+DG CSC D+W
Sbjct:   98 KRVHEDAIRFGFCSDVLLGNALIDMYGKCRCSEGARLVFEGMPFRDVISWTSMASCYVNCGLLREALGAFRKMGLNGERPNSVTVSSILPACTDLKDLKSGREVHGFVVRNGMGGNVFVSSALVNMYASCLSIRQAQLVFDSMSRRDTVSWNVLITAYFLNKECEKGLSVFGRMMSEGVGLNYASWNAVIGGCMQNGRTEKALEVLSRM--QNSGFKPNQITITSVLPACTNLESLRGGKQIHGYIFRHWFFQDLTTTTALVFMYAKCGDLELSRRVFSMM--TKRDTVSWNTMIIATSMHGNGEEALLLFREMVDSGVRPNSVTFTGVLSGCSHSRLVDEGLLIFDSMSRDHSVEPDADHHSCMVDVLSRAGRLEEAYEFIKKMPIEPTAGAWGALLGGCRVYKNVELGRIAANRLFEIESDNPGNYVLLSNILVSAKLWSEASETRKLMRDRGVTKNPGCSWIQVRNRVHTFVVGDKSNDQSDEIYRF-LDYMGEKMRIAGYLPNTDFVLQDVDQEEKEEVLCNHSEKLAVAFGVLNLNGESSIRVFKNLRICGDCHNAIKFMAKIVGVKIIVRDSLRFHHFRDGLCSCQDFW 687          

Query:  154 YLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM-HCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMK 1143
            +L  K + +Y++S DL  A  +F ++  P    +  +I A T HG S E ++ Y    H   ++ D      V K CA L  +   K VH  +++ G  SD+ +G +LI+MY KC     AR +F+ M  RDV SW                               T+M S Y   GL  +AL  F +M       +PN VT+ S+LPAC     L+ GR++H F  R G+  NV + +AL+ MYA C S+  A+  F+ +  ++ + V+WN +ITAY  +    + +S F  M+  GV  +  ++  ++ GC  +G  +  L+    M+
Sbjct:   12 HLALKFIKVYSNSGDLQRARHLFDKIPQPDLPTWTILISALTKHGRSLEAIQYYNDFRHKNCVEPDKLLLLSVAKACASLRDVMNAKRVHEDAIRFGFCSDVLLGNALIDMYGKCRCSEGARLVFEGMPFRDVISW-------------------------------TSMASCYVNCGLLREALGAFRKMGLNGE--RPNSVTVSSILPACTDLKDLKSGREVHGFVVRNGMGGNVFVSSALVNMYASCLSIRQAQLVFDSM--SRRDTVSWNVLITAYFLNKECEKGLSVFGRMMSEGVGLNYASWNAVIGGCMQNGRTEKALEVLSRMQ 307          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM-----------------HCL------------------GLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASR-IGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMI 978
            I  + T    LK G++VH  +   G   + ++ + +V MYAS   +  A  +F  ++   T+ +N +I AY L+   E+ + ++GRM                  C+                  G K +  T   VL  C  L  +  GK +HG   +     D+   T+L+ MY KC D+  +RR+F  MT RD  SWN                                MI   + +G  E+AL LF EM+  DS V+PN VT   VL  C+HS  ++ G  I +  SR   +E +    + ++ + ++ G L +A + F +    +    AW  ++
Sbjct:  185 ILPACTDLKDLKSGREVHGFVVRNGMGGNVFVSSALVNMYASCLSIRQAQLVFDSMSRRDTVSWNVLITAYFLNKECEKGLSVFGRMMSEGVGLNYASWNAVIGGCMQNGRTEKALEVLSRMQNSGFKPNQITITSVLPACTNLESLRGGKQIHGYIFRHWFFQDLTTTTALVFMYAKCGDLELSRRVFSMMTKRDTVSWN-------------------------------TMIIATSMHGNGEEALLLFREMV--DSGVRPNSVTFTGVLSGCSHSRLVDEGLLIFDSMSRDHSVEPDADHHSCMVDVLSRAGRLEEAYE-FIKKMPIEPTAGAWGALL 491          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCV-HGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVS-SWNALIAG 576
            +  + T    L+ G+Q+H  +    F  D      +V MYA   DL+ +  +F  +    T+ +N++I A ++HG  EE + ++  M   G++ ++ T+  VL  C+    +  G  +   +S    +E D    + ++++  +   + +A     KM +   + +W AL+ G
Sbjct:  321 VLPACTNLESLRGGKQIHGYIFRHWFFQDLTTTTALVFMYAKCGDLELSRRVFSMMTKRDTVSWNTMIIATSMHGNGEEALLLFREMVDSGVRPNSVTFTGVLSGCSHSRLVDEGLLIFDSMSRDHSVEPDADHHSCMVDVLSRAGRLEEAYEFIKKMPIEPTAGAWGALLGG 493          

Query:   43 FVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDAR-------------------------------RLFDKMTVRDVS-SWNALI--------------------------------------AGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            F SF++ +      K  L    Q+HAQ+ + G     +L  K V    +  ++  A  +F     PS  L+N+IIR Y+ H F  + +E+Y RM   G+  D FT P VLK C+ +  + +GK VHG   ++G ESD++V   L+ +Y KC  +  AR                               R+F +M  R+V   W AL+                                      A Y K G++ +A   F +M   N++ W AMISGY +NG   +A+ LF EM+ K+  ++ + +T+ S + ACA   +L+  + + ++ ++    ++V + TAL+ M+AKCGS+  AR+ F+R      ++V W+ MI  Y  HGRG +A+  F  M  AGV P+++TF GLL+ C+HSGLV+ G + F  MK  Y +E   +HYACVVDLLGR+G L EA D I  MP++ G S+WGA+L AC+ + ++ + E AA  LF L+P N+G+YV LSN+YA + +W  V  +R+L++ +G+ K+ G S  E+NGK   F  GD SHP+ KEI+E L + L +++K AG++P    VLHD+++EEKE +L  HSE+LAIA+GL++T+PG  LR+TKNLR C +CH+ATKLIS++  REI+VRD NRFHHFK+G CSC DYW
Sbjct:   70 FDSFFSSLLDHSVHKRHLN---QIHAQLVVSGLVESGFLVTKFVNASWNIGEIGYARKVFDEFPEPSVFLWNAIIRGYSSHNFFGDAIEMYSRMQASGVNPDGFTLPCVLKACSGVPVLEVGKRVHGQIFRLGFESDVFVQNGLVALYAKCGRVEQARIVFEGLDDRNIVSWTSMISGYGQNGLPMEALRIFGQMRQRNVKPDWIALVSVLRAYTDVEDLEQGKSIHGCVVKMGLEFEPDLLISLTAMYAKCGQVMVARSFFDQMEIPNVMMWNAMISGYAKNGYTNEAVGLFQEMISKN--IRTDSITVRSAILACAQVGSLDLAKWMGDYINKTEYRNDVFVNTALIDMFAKCGSVDLAREVFDRT--LDKDVVVWSAMIVGYGLHGRGQDAIDLFYAMKQAGVCPNDVTFVGLLTACNHSGLVEEGWELFHSMK-YYGIEARHQHYACVVDLLGRSGHLNEAYDFITTMPIEPGVSVWGALLGACKIYRHVTLGEYAAEQLFSLDPFNTGHYVQLSNLYASSRLWDSVAKVRILMREKGLSKDLGYSLIEINGKLQAFRVGDKSHPRFKEIFEEL-ESLERRLKEAGFIPHIESVLHDLNQEEKEETLCNHSERLAIAYGLISTAPGTTLRITKNLRACINCHSATKLISKLVNREIVVRDANRFHHFKNGVCSCRDYW 742          

Query:  112 VHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDG------EIC-------------------------------LAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNT-----SPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            VH+++ L     ++ LG K++  YAS  D+ SA  +F  +   + ++ N +IR+Y  +GF  E ++++G M    ++ D++T+P VLK C+    I IG+ +HG + KVGL S ++VG  L++MY KC  +S+AR + D+M+ RDV SWN+L+ GY ++       E+C                                 +D+F KM  +++VSW  MI  Y +N +  +A+ L+  M  +    +P+ V+I SVLPAC  ++AL  G+KIH +  R  L  N+ ++ AL+ MYAKCG L  AR  FE ++    ++V+W  MI+AY   GRG +AV+ F  +  +G+ PD+I F   L+ CSH+GL++ G   F  M   Y + P +EH AC+VDLLGRAG++ EA   I  M M+    +WGA+L ACR H + +I  +AA  LF L PE SG YV+LSNIYA+AG W+EV N+R ++K++G+KKNPG S  EVN   H FL GD SHPQ+ EIY   LD L KK+K  GYVPD+   LHDV EE+KE  L  HSEKLAI F L+NT          +R+TKNLRICGDCH A KLIS+I  REII+RD NRFH F+ G CSCGDYW
Sbjct:   61 VHSRIILEDLRCNSSLGVKLMRAYASLKDVASARKVFDEIPERNVIIINVMIRSYVNNGFYGEGVKVFGTMCGCNVRPDHYTFPCVLKACSCSGTIVIGRKIHGSATKVGLSSTLFVGNGLVSMYGKCGFLSEARLVLDEMSRRDVVSWNSLVVGYAQNQRFDDALEVCREMESVKISHDAGTMASLLPAVSNTTTENVMYVKDMFFKMGKKSLVSWNVMIGVYMKNAMPVEAVELYSRM--EADGFEPDAVSITSVLPACGDTSALSLGKKIHGYIERKKLIPNLLLENALIDMYAKCGCLEKARDVFENMK--SRDVVSWTAMISAYGFSGRGCDAVALFSKLQDSGLVPDSIAFVTTLAACSHAGLLEEGRSCFKLMTDHYKITPRLEHLACMVDLLGRAGKVKEAYRFIQDMSMEPNERVWGALLGACRVHSDTDIGLLAADKLFQLAPEQSGYYVLLSNIYAKAGRWEEVTNIRNIMKSKGLKKNPGASNVEVNRIIHTFLVGDRSHPQSDEIYR-ELDVLVKKMKELGYVPDSESALHDVEEEDKETHLAVHSEKLAIVFALMNTKEEEEDSNNTIRITKNLRICGDCHVAAKLISQITSREIIIRDTNRFHVFRFGVCSCGDYW 686          

Query:  811 RKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAM-------------LSACRKHHNLEIAEIAARSLFIL 1353
            R +H+      L  N S+   L+  YA    +  AR+ F+ +   + N++  N MI +Y ++G   E V  F  M    V+PD+ TF  +L  CS SG + +G K      +V  +   +     +V + G+ G L+EA+ ++ +M  +   S W ++             L  CR+  +++I+  A     +L
Sbjct:   59 RTVHSRIILEDLRCNSSLGVKLMRAYASLKDVASARKVFDEI--PERNVIIINVMIRSYVNNGFYGEGVKVFGTMCGCNVRPDHYTFPCVLKACSCSGTIVIGRKIHGSATKV-GLSSTLFVGNGLVSMYGKCGFLSEARLVLDEMSRRDVVS-WNSLVVGYAQNQRFDDALEVCREMESVKISHDAGTMASLL 248          

Query:  109 QVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAE----LSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +VH  +   G + D +L  K++ MY+    +D A  +F +    +  ++N++ RA TL G  EE + +Y +M+ +G++ D FTY +VLK C      ++ +  GK +H    + G  S +Y+ T+L++MY +                                G +  A  +FG MP RN+VSW+AMI+ Y +NG A +AL  F EM+++     PN VT++SVL ACA  AALE+G+ IH +  R GL+S + + +AL+ MY +CG L   ++ F+R+     ++V+WN++I++Y  HG G +A+  FE+M+  G  P  +TF  +L  CSH GLV+ G + F+ M R + ++P +EHYAC+VDLLGRA RL EA  ++  M  + GP +WG++L +CR H N+E+AE A+R LF LEP+N+GNYV+L++IYAEA MW EV  ++ LL+ +G++K PG  W EV  K + F+  D  +P  ++I+ FL+ +L + +K  GY+P T  VL+++  EEKE  +  HSEKLA+AFGL+NTS G  +R+TKNLR+C DCH  TK IS+  E+EI+VRD+NRFH FK+G CSCGDYW
Sbjct:   98 RVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTRKRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIGVESDRFTYTYVLKACVASECTVNHLMKGKEIHAHLTRRGYSSHVYIMTTLVDMYARF-------------------------------GCVDYASYVFGGMPVRNVVSWSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSVLQACASLAALEQGKLIHGYILRRGLDSILPVISALVTMYGRCGKLEVGQRVFDRMH--DRDVVSWNSLISSYGVHGYGKKAIQIFEEMLANGASPTPVTFVSVLGACSHEGLVEEGKRLFETMWRDHGIKPQIEHYACMVDLLGRANRLDEAAKMVQDMRTEPGPKVWGSLLGSCRIHGNVELAERASRRLFALEPKNAGNYVLLADIYAEAQMWDEVKRVKKLLEHRGLQKLPGRCWMEVRRKMYSFVSVDEFNPLMEQIHAFLV-KLAEDMKEKGYIPQTKGVLYELETEEKERIVLGHSEKLALAFGLINTSKGEPIRITKNLRLCEDCHLFTKFISKFMEKEILVRDVNRFHRFKNGVCSCGDYW 657          

Query:   88 NLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM--HCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASR-IGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHG 999
            N L  G+++HA +  RG+    Y+   +V MYA    +D A  +F  +   + + ++++I  Y  +G + E +  +  M         ++ T   VL+ CA L+ +  GK +HG  L+ GL+S + V ++L+ MY +C  +   +R+FD+M  RDV SWN+L                               IS Y  +G  ++A+ +F+EML   +   P  VT +SVL AC+H   +E G+++     R  G++  +     ++ +  +   L +A +  + +R T+     W +++ +   HG
Sbjct:  196 NHLMKGKEIHAHLTRRGYSSHVYIMTTLVDMYARFGCVDYASYVFGGMPVRNVVSWSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSVLQACASLAALEQGKLIHGYILRRGLDSILPVISALVTMYGRCGKLEVGQRVFDRMHDRDVVSWNSL-------------------------------ISSYGVHGYGKKAIQIFEEMLANGASPTP--VTFVSVLGACSHEGLVEEGKRLFETMWRDHGIKPQIEHYACMVDLLGRANRLDEAAKMVQDMR-TEPGPKVWGSLLGSCRIHG 468          

Query:  643 VSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLL-----SGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNI 1395
            +S   +I    + G  +QA+     +L ++S   P+  T   ++  C H ++L    ++H      G + +  + T L+ MY+  GS+  AR+ F++ R  +  +  WN +  A    G G E +  +  M   GV+ D  T+T +L     S C+ + L+     +    +R YS    V     +VD+  R G +  A  +   MP++   S W AM++   K+     A    R +     ++S N V + ++
Sbjct:   47 ISNNQLIQSLCKEGKLKQAI----RVLSQESS--PSQQTYELLILCCGHRSSLSDALRVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTR--KRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIGVESDRFTYTYVLKACVASECTVNHLMKGKEIHAHLTRRGYSSH--VYIMTTLVDMYARFGCVDYASYVFGGMPVRNVVS-WSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSV 291          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNP-----STLL------------------------------YNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +F+     +  K+G+Q+H    + G + DA++   M  MY     +  A  +F R+++      S LL                              +N I+  +   G+ +E + ++ ++H LG   D  T   VL    +   + +G+ +HG  +K GL  D  V +++I+MY K   +     LF++  + +    NA I G  ++G +  A ++F     +    N+VSWT++I+G  QNG   +AL LF EM  + + VKPN VTI S+LPAC + AAL  GR  H FA R+ L  NV + +AL+ MYAKCG +  ++  F  +     NLV WN+++  ++ HG+  E +S FE ++   ++PD I+FT LLS C   GL D G KYF  M   Y ++P +EHY+C+V+LLGRAG+L EA DLI +MP +    +WGA+L++CR  +N+++AEIAA  LF LEPEN G YV+LSNIYA  GMW EVD++R  +++ G+KKNPGCSW +V  + +  L GD SHPQ  +I E  +DE+ K+++ +G+ P+  F LHDV E+E+E  L  HSEKLA+ FGLLNT  G  L+V KNLRICGDCH   K IS    REI +RD NRFHHFKDG CSCGD+W
Sbjct:  122 LFKVCAELSAFKVGKQIHCVSCVSGLDMDAFVQGSMFHMYMRCGRMGDARKVFDRMSDKDVVTCSALLCAYARKGCLEEVVRILSEMESSGIEANIVSWNGILSGFNRSGYHKEAVVMFQKIHHLGFCPDQVTVSSVLPSVGDSEMLNMGRLIHGYVIKQGLLKDKCVISAMIDMYGKSGHVYGIISLFNQFEMMEAGVCNAYITGLSRNGLVDKALEMFELFKEQTMELNVVSWTSIIAGCAQNGKDIEALELFREM--QVAGVKPNHVTIPSMLPACGNIAALGHGRSTHGFAVRVHLLDNVHVGSALIDMYAKCGRINLSQIVFNMM--PTKNLVCWNSLMNGFSMHGKAKEVMSIFESLMRTRLKPDFISFTSLLSACGQVGLTDEGWKYFKMMSEEYGIKPRLEHYSCMVNLLGRAGKLQEAYDLIKEMPFEPDSCVWGALLNSCRLQNNVDLAEIAAEKLFHLEPENPGTYVLLSNIYAAKGMWTEVDSIRNKMESLGLKKNPGCSWIQVKNRVYTLLAGDKSHPQIDQITE-KMDEISKEMRKSGHRPNLDFALHDVEEQEQEQMLWGHSEKLAVVFGLLNTPDGTPLQVIKNLRICGDCHAVIKFISSYAGREIFIRDTNRFHHFKDGICSCGDFW 760          

Query:  109 QVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAE--DLFGKMPG----RNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCG------------SLLDARQC-------------------FE--RVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            Q HA++   G + D Y+ AK++A Y++ +  + A  +   + +P+   ++S+I A T      +++ ++ RM   GL  D+   P + K CAELS   +GK +H +S   GL+ D +V  S+ +MY++C  M DAR++FD+M+ +DV + +AL+  Y + G  CL E   +  +M       NIVSW  ++SG+ ++G  ++A+ +F ++        P+ VT+ SVLP+   S  L  GR IH +  + GL  +  + +A++ MY K G             +++A  C                   FE  + +  + N+V+W ++I   A +G+  EA+  F +M VAGV+P+++T   +L  C +   +  G     +  RV+ ++  V   + ++D+  + GR+  ++ +   MP +     W ++++    H
Sbjct:   36 QAHARILKSGAQNDGYISAKLIASYSNYNCFNDADLVLQSIPDPTIYSFSSLIYALTKAKLFTQSIGVFSRMFSHGLIPDSHVLPNLFKVCAELSAFKVGKQIHCVSCVSGLDMDAFVQGSMFHMYMRCGRMGDARKVFDRMSDKDVVTCSALLCAYARKG--CLEEVVRILSEMESSGIEANIVSWNGILSGFNRSGYHKEAVVMFQKI--HHLGFCPDQVTVSSVLPSVGDSEMLNMGRLIHGYVIKQGLLKDKCVISAMIDMYGKSGHVYGIISLFNQFEMMEAGVCNAYITGLSRNGLVDKALEMFELFKEQTMELNVVSWTSIIAGCAQNGKDIEALELFREMQVAGVKPNHVTIPSMLPACGNIAALGHGRSTHGFAVRVHLLD-NVHVGSALIDMYAKCGRINLSQIVFNMMPTK-NLVCWNSLMNGFSMH 467          

Query:  232 NNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDV-SEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +N   + YN++I  Y   GF +E +E+  RM   G++ D FTYP V++ CA    + +GK VH   L+   +   +   SL+++Y KC    +AR +F+KM  +D+ SWNAL++GY+  G I  A+ +F +M  +NI+SW  MISG  +NG  E+ L LF  M  K    +P        + +CA   A   G++ H    +IG +S++S   AL+ MYAKCG + +ARQ F  +    +  V+WN +I A   HG G+EAV  +E+M+  G++PD IT   +L+ CSH+GLVD G KYFD M+ VY + PG +HYA ++DLL R+G+ ++A+ +I  +P +    IW A+LS CR H N+E+  IAA  LF L PE+ G Y++LSN++A  G W+EV  +R L++ +GVKK   CSW E+  + H FL  DTSHP+A+ +Y +L D L K+++  GYVPDTSFVLHDV S+  KE  LTTHSEK+A+AFGL+   PG  +R+ KNLR CGDCH   + +S + +R+II+RD  RFHHF++G CSCG++W
Sbjct:  247 DNMKLVAYNAMISGYVNRGFYQEALEMVRRMVSSGIELDEFTYPSVIRACATAGLLQLGKQVHAYVLRRE-DFSFHFDNSLVSLYYKCGKFDEARAIFEKMPAKDLVSWNALLSGYVSSGHIGEAKLIFKEMKEKNILSWMIMISGLAENGFGEEGLKLFSCM--KREGFEPCDYAFSGAIKSCAVLGAYCNGQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDS--VSWNALIAALGQHGHGAEAVDVYEEMLKKGIRPDRITLLTVLTACSHAGLVDQGRKYFDSMETVYRIPPGADHYARLIDLLCRSGKFSDAESVIESLPFKPTAEIWEALLSGCRVHGNMELGIIAADKLFGLIPEHDGTYMLLSNMHAATGQWEEVARVRKLMRDRGVKKEVACSWIEMETQVHTFLVDDTSHPEAEAVYIYLQD-LGKEMRRLGYVPDTSFVLHDVESDGHKEDMLTTHSEKIAVAFGLMKLPPGTTIRIFKNLRTCGDCHNFFRFLSWVVQRDIILRDRKRFHHFRNGECSCGNFW 790          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPS---------------------------------TLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCV--HGLSLKVGLESDMYVGTSLINMYVKCCD----MSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLF-GKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEP--------------------GVEHYA---------------CVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH-HNLEIAEI 1329
            L+L + VH  +   GF+P A++  +++ +Y  S +L+ A  +F  ++ P                                  T++YN++I  ++ +      + ++ +M   G K DNFT+  VL   A L      +CV  H  +LK G      V  +L+++Y KC      +  AR++FD++  +D  SW  ++ GY+K+G   L E+L  G      +V++ AMISGY   G  ++AL +   M+   S ++ +  T  SV+ ACA +  L+ G+++H +  R   + +     +L+++Y KCG   +AR  FE++     +LV+WN +++ Y S G   EA   F++M     + + +++  ++SG + +G  + GLK F  MKR    EP                    G +++A                ++ +  + G + EA+ +   MP     S W A+++A  +H H  E  ++
Sbjct:   30 LQLARAVHGNIITFGFQPRAHILNRLIDVYCKSSELNYARQLFDEISEPDKIARTTMVSGYCASGDITLARGVFEKAPVCMRDTVMYNAMITGFSHNNDGYSAINLFCKMKHEGFKPDNFTFASVLAGLA-LVADDEKQCVQFHAAALKSGAGYITSVSNALVSVYSKCASSPSLLHSARKVFDEILEKDERSWTTMMTGYVKNGYFDLGEELLEGMDDNMKLVAYNAMISGYVNRGFYQEALEMVRRMV--SSGIELDEFTYPSVIRACATAGLLQLGKQVHAYVLR-REDFSFHFDNSLVSLYYKCGKFDEARAIFEKM--PAKDLVSWNALLSGYVSSGHIGEAKLIFKEM----KEKNILSWMIMISGLAENGFGEEGLKLFSCMKR-EGFEPCDYAFSGAIKSCAVLGAYCNGQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDSVS-WNALIAALGQHGHGAEAVDV 505          

Query:  358 YPFVLKCCAELSR--IWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMP--GRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERG-RKIHNFASRIGLESNVSIQTALLAMYAKCGS----LLDARQCFERVRXTQN------------------------------NLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQG 1458
            Y   L+ C  L R  + + + VHG  +  G +   ++   LI++Y K  +++ AR+LFD+++  D  +   +++GY   G+I LA  +F K P   R+ V + AMI+G++ N     A+ LF +M  K    KP+  T  SVL   A  A  E+   + H  A + G     S+  AL+++Y+KC S    L  AR+ F+ +                                    LVA+N MI+ Y + G   EA+     M+ +G++ D  T+  ++  C+ +GL+ +G +   Y+ R        ++   +V L  + G+  EA+ +  KMP +   S W A+LS      ++  A++  +    ++ +N  +++++ +  AE G  +E   L   +K +G
Sbjct:   15 YAANLRLCLPLRRTSLQLARAVHGNIITFGFQPRAHILNRLIDVYCKSSELNYARQLFDEISEPDKIARTTMVSGYCASGDITLARGVFEKAPVCMRDTVMYNAMITGFSHNNDGYSAINLFCKM--KHEGFKPDNFTFASVLAGLALVADDEKQCVQFHAAALKSGAGYITSVSNALVSVYSKCASSPSLLHSARKVFDEILEKDERSWTTMMTGYVKNGYFDLGEELLEGMDDNMKLVAYNAMISGYVNRGFYQEALEMVRRMVSSGIELDEFTYPSVIRACATAGLLQLGKQVHAYVLRREDFSFHFDN--SLVSLYYKCGKFDEARAIFEKMPAKDLVS-WNALLSGYVSSGHIGEAKLIFKE---MKEKNILSWMIMISGLAENGFGEEGLKLFSCMKREG 412          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTL-------------------------------HGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI-GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHG 999
            Y  + ++     LL+LG+QVHA + LR  +   +    +V++Y      D A AIF ++     + +N+++  Y                                 +GF EE ++++  M   G +  ++ +   +K CA L     G+  H   LK+G +S +  G +LI MY KC  + +AR++F  M   D  SWNALIA                                  Q+G   +A+ +++EMLKK   ++P+ +T+++VL AC+H+  +++GRK  +    +  +         L+ +  + G   DA    E +       + W  +++    HG
Sbjct:  289 YPSVIRACATAGLLQLGKQVHAYV-LRREDFSFHFDNSLVSLYYKCGKFDEARAIFEKMPAKDLVSWNALLSGYVSSGHIGEAKLIFKEMKEKNILSWMIMISGLAENGFGEEGLKLFSCMKREGFEPCDYAFSGAIKSCAVLGAYCNGQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDSVSWNALIA-------------------------------ALGQHGHGAEAVDVYEEMLKKG--IRPDRITLLTVLTACSHAGLVDQGRKYFDSMETVYRIPPGADHYARLIDLLCRSGKFSDAESVIESLPFKPTAEI-WEALLSGCRVHG 600          

Query:  103 GQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHG---LSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSS-WNALIAGYMKDGE----ICLAEDLFGKMP 630
            GQQ HAQ+   GF+     G  ++ MYA    ++ A  +F  +    ++ +N++I A   HG   E +++Y  M   G++ D  T   VL  C+    +  G+          ++   +D Y    LI++  +    SDA  + + +  +  +  W AL++G    G     I  A+ LFG +P
Sbjct:  436 GQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDSVSWNALIAALGQHGHGAEAVDVYEEMLKKGIRPDRITLLTVLTACSHAGLVDQGRKYFDSMETVYRIPPGADHY--ARLIDLLCRSGKFSDAESVIESLPFKPTAEIWEALLSGCRVHGNMELGIIAADKLFGLIP 617          

Query:   49 SFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVG---------------------------------TSLINMYVKCCDMSDARRLFDKMTVRDVS-SWNALIAG--------------------------------------YMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            SFYA +  S T K  LK   Q+HA++ + G +   +L  K++   +S  D+  A  +F  +  P    +N+IIR Y+ +   ++ + +Y  M    +  D+FT+P +LK C+ LS + +G+ VH    ++G ++D++V                                  T++++ Y +  +  +A  +F +M   DV   W AL++                                       Y K G++  A+ LF KM   N++ W AMISGY +NG A +A+ +F EM+ KD  V+P+ ++I S + ACA   +LE+ R ++ +  R     +V I +AL+ M+AKCGS+  AR  F+R      ++V W+ MI  Y  HGR  EA+S +  M   GV P+++TF GLL  C+HSG+V  G  +F+ M   + + P  +HYACV+DLLGRAG L +A ++I  MP+Q G ++WGA+LSAC+KH ++E+ E AA+ LF ++P N+G+YV LSN+YA A +W  V  +RV +K +G+ K+ GCSW EV G+   F  GD SHP+ +EI E  ++ +  ++K  G+V +    LHD+++EE E +L +HSE++AIA+GL++T  G  LR+TKNLR C +CH ATKLIS++ +REI+VRD NRFHHFKDG CSCGDYW
Sbjct:   22 SFYASLIDSATHKAQLK---QIHARLLVLGLQFSGFLITKLIHASSSFGDITFARQVFDDLPRPQIFPWNAIIRGYSRNNHFQDALLMYSNMQLARVSPDSFTFPHLLKACSGLSHLQMGRFVHAQVFRLGFDADVFVQNGLIALYAKCRRLGSARTVFEGLPLPERTIVSWTAIVSAYAQNGEPMEALEIFSQMRKMDVKPDWVALVSVLNAFTCLQDLKQGRSIHASVVKMGLEIEPDLLISLNTMYAKCGQVATAKILFDKMKSPNLILWNAMISGYAKNGYAREAIDMFHEMINKD--VRPDTISITSAISACAQVGSLEQARSMYEYVGRSDYRDDVFISSALIDMFAKCGSVEGARLVFDRT--LDRDVVVWSAMIVGYGLHGRAREAISLYRAMERGGVHPNDVTFLGLLMACNHSGMVREGWWFFNRMAD-HKINPQQQHYACVIDLLGRAGHLDQAYEVIKCMPVQPGVTVWGALLSACKKHRHVELGEYAAQQLFSIDPSNTGHYVQLSNLYAAARLWDRVAEVRVRMKEKGLNKDVGCSWVEVRGRLEAFRVGDKSHPRYEEI-ERQVEWIESRLKEGGFVANKDASLHDLNDEEAEETLCSHSERIAIAYGLISTPQGTPLRITKNLRACVNCHAATKLISKLVDREIVVRDTNRFHHFKDGVCSCGDYW 694          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSD----DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEI---YGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDK---------MTVR-----DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +F  +     ++   Q+HA     G   D    A+++   A+SD    DLD A  IF+++   +   +N+IIR ++     +  + I   Y  M    ++ + FT+P VLK CA+  +I  GK +HGL+LK G   D +V ++L+ MYV C  M DAR LF K         MT R     ++  WN +I GYM+ G+   A  LF KM  R++VSW  MISGY+ NG  + A+ +F EM K D  ++PN+VT++SVLPA +   +LE G  +H +A   G+  +  + +AL+ MY+KCG +  A   FER+   + N++ W+ MI  +A HG+  +A+  F  M  AGV+P ++ +  LL+ CSH GLV+ G +YF  M  V  +EP +EHY C+VDLLGR+G L EA++ I  MP++    IW A+L ACR   N+E+ +  A  L  + P +SG YV LSN+YA  G W EV  +R+ +K + ++K+PGCS  +++G  H F+  D SHP+AKEI   L+ E+  K++ AGY P T+ VL ++ EE+KE+ L  HSEK+A AFGL++TSPG  +R+ KNLRIC DCH++ KLIS++Y+R+I VRD  RFHHF+DG+CSC DYW
Sbjct:   26 LFPQINNCRTIRDLSQIHAVFIKSGQMRDTLAAAEILRFCATSDLHHRDLDYAHKIFNQMPQRNCFSWNTIIRGFSESDEDKALIAITLFYEMMSDEFVEPNRFTFPSVLKACAKTGKIQEGKQIHGLALKYGFGGDEFVMSNLVRMYVMCGFMKDARVLFYKNIIEKDMVVMTDRRKRDGEIVLWNVMIDGYMRLGDCKAARMLFDKMRQRSVVSWNTMISGYSLNGFFKDAVEVFREMKKGD--IRPNYVTLVSVLPAISRLGSLELGEWLHLYAEDSGIRIDDVLGSALIDMYSKCGIIEKAIHVFERL--PRENVITWSAMINGFAIHGQAGDAIDCFCKMRQAGVRPSDVAYINLLTACSHGGLVEEGRRYFSQMVSVDGLEPRIEHYGCMVDLLGRSGLLDEAEEFILNMPIKPDDVIWKALLGACRMQGNVEMGKRVANILMDMVPHDSGAYVALSNMYASQGNWSEVSEMRLRMKEKDIRKDPGCSLIDIDGVLHEFVVEDDSHPKAKEINSMLV-EISDKLRLAGYRPITTQVLLNLEEEDKENVLHYHSEKIATAFGLISTSPGKPIRIVKNLRICEDCHSSIKLISKVYKRKITVRDRKRFHHFQDGSCSCMDYW 646          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEE-KEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            L LGQ +H          D ++   ++  Y S  DLDSA  +F  +     + +NS+I  +   G  ++ +E++ +M    +K  + T   VL  CA++  +  G+ V     +  +  ++ +  ++++MY KC  + DA+RLFD M  +D  +W  ++ GY    +   A ++   MP ++IV+W A+IS Y QNG   +AL +F E L+    +K N +T++S L ACA   ALE GR IH++  + G+  N  + +AL+ MY+KCG L  +R+ F  V   + ++  W+ MI   A HG G+EAV  F  M  A V+P+ +TFT +   CSH+GLVD     F  M+  Y + P  +HYAC+VD+LGR+G L +A   I  MP+    S+WGA+L AC+ H NL +AE+A   L  LEP N G +V+LSNIYA+ G W+ V  LR  ++  G+KK PGCS  E++G  H FL GD +HP ++++Y   L E+ +K+K+ GY P+ S VL  + EEE KE SL  HSEKLAI +GL++T    V+RV KNLR+CGDCH+  KLIS++Y+REIIVRD  RFHHF++G CSC D+W
Sbjct:  147 LSLGQSLHGMAVKSAVGSDVFVANSLIHCYFSCGDLDSACKVFTTIKEKDVVSWNSMINGFVQKGSPDKALELFKKMESEDVKASHVTMVGVLSACAKIRNLEFGRQVCSYIEENRVNVNLTLANAMLDMYTKCGSIEDAKRLFDAMEEKDNVTWTTMLDGYAISEDYEAAREVLNSMPQKDIVAWNALISAYEQNGKPNEALIVFHE-LQLQKNMKLNQITLVSTLSACAQVGALELGRWIHSYIKKHGIRMNFHVTSALIHMYSKCGDLEKSREVFNSVE--KRDVFVWSAMIGGLAMHGCGNEAVDMFYKMQEANVKPNGVTFTNVFCACSHTGLVDEAESLFHQMESNYGIVPEEKHYACIVDVLGRSGYLEKAVKFIEAMPIPPSTSVWGALLGACKIHANLNLAEMACTRLLELEPRNDGAHVLLSNIYAKLGKWENVSELRKHMRVTGLKKEPGCSSIEIDGMIHEFLSGDNAHPMSEKVYG-KLHEVMEKLKSNGYEPEISQVLQIIEEEEMKEQSLNLHSEKLAICYGLISTEAPKVIRVIKNLRVCGDCHSVAKLISQLYDREIIVRDRYRFHHFRNGQCSCNDFW 738          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSD--DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKX---DNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQN-----------------------------NLVAWNTMITAYASHGRGSEAVSTFEDM-IVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            +Q H  M   G   D Y  +K+ AM A S    L+ A  +F  +  P++  +N++IRAY      +  + I+  +  +       + +T+PF++K  AE+S + +G+ +HG+++K  + SD++V  SLI+ Y  C D+  A ++F  +  +DV SWN++I G++                               Q G  ++AL LF +M  +D  VK + VT++ VL ACA    LE GR++ ++     +  N+++  A+L MY KCGS+ DA++ F+ +    N                             ++VAWN +I+AY  +G+ +EA+  F ++ +   ++ + IT    LS C+  G +++G     Y+K+ + +       + ++ +  + G L +++++   +  +    +W AM+     H
Sbjct:   47 KQTHGHMIRTGTFSDPYSASKLFAMAALSSFASLEYARKVFDEIPKPNSFAWNTLIRAYA--SGPDPVLSIWAFLDMVSESQCYPNKYTFPFLIKAAAEVSSLSLGQSLHGMAVKSAVGSDVFVANSLIHCYFSCGDLDSACKVFTTIKEKDVVSWNSMINGFV-------------------------------QKGSPDKALELFKKMESED--VKASHVTMVGVLSACAKIRNLEFGRQVCSYIEENRVNVNLTLANAMLDMYTKCGSIEDAKRLFDAMEEKDNVTWTTMLDGYAISEDYEAAREVLNSMPQKDIVAWNALISAYEQNGKPNEALIVFHELQLQKNMKLNQITLVSTLSACAQVGALELGRWIHSYIKK-HGIRMNFHVTSALIHMYSKCGDLEKSREVFNSVE-KRDVFVWSAMIGGLAMH 444          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYA------------------------SSDD------------LDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +  + +S T    L+ G+ VH  +   G + D Y G  ++ MYA                        S D+            +DS   +F  +     + YN+II  Y   G  E+ + +   M    LK D+FT   VL   +E   +  GK +HG  ++ G++SD+Y+G+SL++MY K   + D+ R+F ++              Y +DG                 +SW ++++GY QNG   +AL LF +M+   +KVKP  V   SV+PACAH A L  G+++H +  R G  SN+ I +AL+ MY+KCG++  AR+ F+R+       V+W  +I  +A HG G EAVS FE+M   GV+P+ + F  +L+ CSH GLVD    YF+ M +VY +   +EHYA V DLLGRAG+L EA + I KM ++   S+W  +LS+C  H NLE+AE  A  +F ++ EN G YV++ N+YA  G WKE+  LR+ ++ +G++K P CSW E+  K H F+ GD SHP   +I EF L  + ++++  GYV DTS VLHDV EE K   L  HSE+LA+AFG++NT PG  +RVTKN+RIC DCH A K IS+I EREIIVRD +RFHHF  GNCSCGDYW
Sbjct:  108 FPSVLKSCTMMMDLRFGESVHGFIVRLGMDCDLYTGNALMNMYAKLLGMGSKISVGNVFDEMPQRTSNSGDEDVKAETCIMPFGIDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTDLKPDSFTLSSVLPIFSEYVDVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRL--------------YCRDG-----------------ISWNSLVAGYVQNGRYNEALRLFRQMVT--AKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDE--VSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTKVYGLNQELEHYAAVADLLGRAGKLEEAYNFISKMCVEPTGSVWSTLLSSCSVHKNLELAEKVAEKIFTVDSENMGAYVLMCNMYASNGRWKEMAKLRLRMRKKGLRKKPACSWIEMKNKTHGFVSGDRSHPSMDKINEF-LKAVMEQMEKEGYVADTSGVLHDVDEEHKRELLFGHSERLAVAFGIINTEPGTTIRVTKNIRICTDCHVAIKFISKITEREIIVRDNSRFHHFNRGNCSCGDYW 715          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMS---DARRLFDKMTVRDVSSWNALIAGYMKDGEICL-------AEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKM 1248
            +Q+HAQ  +R         + ++++Y +   L  A+ +F  + +P  L + S+IR +T      + +  +  M   G   D+  +P VLK C  +  +  G+ VHG  +++G++ D+Y G +L+NMY K   M        +FD+M  R  +S +  +       E C+          +F  MP +++VS+  +I+GY Q+G+ E AL +  EM   D  +KP+  T+ SVLP  +    + +G++IH +  R G++S+V I ++L+ MYAK   + D+ + F R+       ++WN+++  Y  +GR +EA+  F  M+ A V+P  + F+ ++  C+H   + +G +   Y+ R       +   + +VD+  + G +  A+ +  +M
Sbjct:   25 KQLHAQF-IRTQSLSHTSASIVISIYTNLKLLHEALLLFKTLKSPPVLAWKSVIRCFTDQSLFSKALASFVEMRASGRCPDHNVFPSVLKSCTMMMDLRFGESVHGFIVRLGMDCDLYTGNALMNMYAKLLGMGSKISVGNVFDEMPQRTSNSGDEDV-----KAETCIMPFGIDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTD--LKPDSFTLSSVLPIFSEYVDVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDG--ISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLR-GGFGSNIFIASALVDMYSKCGNIKAARKIFDRM 404          

Query:   25 LAQDPRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERV-RXTQNNLVAWNTMITAYASHGRGSE 1011
            L  D   +S   PIF      +++K G+++H  +  +G + D Y+G+ +V MYA S  ++ +  +F R+     + +NS++  Y  +G   E + ++ +M    +K     +  V+  CA L+ + +GK +HG  L+ G  S++++ ++L++MY KC ++  AR++FD+M V D  SW A+I G+   G    A  LF +M  +    N V++ A+++  +  GL ++A   F+ M K    +        +V      +  LE   + +NF S++ +E   S+ + LL+  +   +L  A +  E++      N+ A+  M   YAS+GR  E
Sbjct:  238 LKPDSFTLSSVLPIFSEYV--DVIK-GKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTKVYG-LNQELEHYAAVADLLGRAGKLE---EAYNFISKMCVEPTGSVWSTLLSSCSVHKNLELAEKVAEKIFTVDSENMGAYVLMCNMYASNGRWKE 564          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMY---ASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHD-VSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +Q+HA+M   G   D+Y   K ++      SSD L  A  +F   + P T L+N +IR ++     E ++ +Y RM C     + +T+P +LK C+ LS       +H    K+G E+D+Y   SLIN Y    +   A  LFD++   D  SWN++I GY+K G++ +A  LF KM  +N +SWT MISGY Q  + ++AL LF EM  ++S V+P+ V++ + L ACA   ALE+G+ IH++ ++  +  +  +   L+ MYAKCG + +A + F+ ++  + ++ AW  +I+ YA HG G EA+S F +M   G++P+ ITFT +L+ CS++GLV+ G   F  M+R Y+++P +EHY C+VDLLGRAG L EAK  I +MP++    IWGA+L ACR H N+E+ E     L  ++P + G YV  +NI+A    W +    R L+K QGV K PGCS   + G  H FL GD SHP+ ++I +     + +K++  GYVP+   +L D V ++E+E  +  HSEKLAI +GL+ T PG ++R+ KNLR+C DCH  TKLIS+IY+R+I++RD  RFHHF+DG CSCGDYW
Sbjct:   31 KQIHARMLKTGLMQDSYAITKFLSFCISSTSSDFLPYAQIVFDGFDRPDTFLWNLMIRGFSCSDEPERSLLLYQRMLCSSAPHNAYTFPSLLKACSNLSAFEETTQIHAQITKLGYENDVYAVNSLINSYAVTGNFKLAHLLFDRIPEPDDVSWNSVIKGYVKAGKMDIALTLFRKMAEKNAISWTTMISGYVQADMNKEALQLFHEM--QNSDVEPDNVSLANALSACAQLGALEQGKWIHSYLNKTRIRMDSVLGCVLIDMYAKCGEMEEALEVFKNIK--KKSVQAWTALISGYAYHGHGREAISKFMEMQKMGIKPNVITFTAVLTACSYTGLVEEGKLIFYSMERDYNLKPTIEHYGCIVDLLGRAGLLDEAKRFIQEMPLKPNAVIWGALLKACRIHKNIELGEEIGEILIAIDPYHGGRYVHKANIHAMDKKWDKAAETRRLMKEQGVAKVPGCSTISLEGTTHEFLAGDRSHPEIEKI-QSKWRIMRRKLEENGYVPELEEMLLDLVDDDEREAIVHQHSEKLAITYGLIKTKPGTIIRIMKNLRVCKDCHKVTKLISKIYKRDIVMRDRTRFHHFRDGKCSCGDYW 620          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCV-HGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDL 615
            L+ G+ +H+ +       D+ LG  ++ MYA   +++ A+ +F  +   S   + ++I  Y  HG   E +  +  M  +G+K +  T+  VL  C+    +  GK + + +     L+  +     ++++  +   + +A+R   +M ++ +   W AL+        I L E++
Sbjct:  263 LEQGKWIHSYLNKTRIRMDSVLGCVLIDMYAKCGEMEEALEVFKNIKKKSVQAWTALISGYAYHGHGREAISKFMEMQKMGIKPNVITFTAVLTACSYTGLVEEGKLIFYSMERDYNLKPTIEHYGCIVDLLGRAGLLDEAKRFIQEMPLKPNAVIWGALLKACRIHKNIELGEEI 438          

Query:   91 LLKLGQQVHAQMALRG-FEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIY-GRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKV---------KPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPS-IWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +L+ G+++HA     G  + ++++G+ +V MY +   + S   +F  + +    L+N++I  Y+ +   +E + ++ G     GL  ++ T   V+  C         + +HG  +K GL+ D +V  +L++MY +                                G+I +A  +FGKM  R++V+W  MI+GY  +   E AL L  +M   + KV         KPN +T+M++LP+CA  +AL +G++IH +A +  L ++V++ +AL+ MYAKCG L  +R+ F+++   Q N++ WN +I AY  HG G EA+     M+V GV+P+ +TF  + + CSHSG+VD GL+ F  MK  Y VEP  +HYACVVDLLGRAGR+ EA  L+  MP     +  W ++L A R H+NLEI EIAA++L  LEP  + +YV+L+NIY+ AG+W +   +R  +K QGV+K PGCSW E   + H F+ GD+SHPQ++++  +L + L ++++  GYVPDTS VLH+V E+EKE  L  HSEKLAIAFG+LNTSPG ++RV KNLR+C DCH ATK IS+I +REII+RD+ RFH FK+G CSCGDYW
Sbjct:  317 MLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRL-------------------------------GKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQI--PQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYL-ETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVG-LESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEA------VSTFEDMIVAG-----VQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHN 1311
            L +G+QVHA   LR  E ++++   +VAMY     L S+  +         + +N+++ +   +    E +E    M   G++ D FT   VL  C+ L  +  GK +H  +LK G L+ + +VG++L++MY  C  +   RR+FD M  R +  WNA+IA                               GY+QN   ++AL LF  M ++ + +  N  T+  V+PAC  S A  R   IH F  + GL+ +  +Q  L+ MY++ G +  A + F ++     +LV WNTMIT Y       +A      +   E  +  G     ++P++IT   +L  C+    +  G +   Y  +  ++   V   + +VD+  + G L  ++ +  ++P Q     W  ++ A   H N
Sbjct:  218 LMMGKQVHAY-GLRKGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIA-------------------------------GYSQNEHDKEALLLFIGM-EESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKME--DRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIK-NNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIP-QKNVITWNVIIMAYGMHGN 598          

Query:  262 IIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESD-MYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAH---SAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSA-CRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGM 1413
            ++R+        E +  Y  M  LG+K DN+ +P +LK  A+L  + +GK +H    K G   D + V  +L+N+Y KC D     ++                               F ++  RN VSW ++IS        E AL  F  ML  D  V+P+  T++SV+ AC++      L  G+++H +  R G E N  I   L+AMY K G L  ++           +LV WNT++++   + +  EA+    +M++ GV+PD  T + +L  CSH  ++  G +   Y  +  S++      + +VD+     ++   + +   M       +W AM++   +  H+ E     A  LFI   E++G   +L+N    AG+
Sbjct:   68 LLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKV-------------------------------FDRISERNQVSWNSLISSLCSFEKWEMALEAFRCML--DENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKG-ELNSFIINTLVAMYGKLGKLASSKVLLGSFGG--RDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGM-FDRKIGLWNAMIAGYSQNEHDKE-----ALLLFIGMEESAG---LLANSTTMAGV 411          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAK-MVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAEL---SRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIG-LESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDM-IVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDY-MKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKM 1248
            ++LG+Q+HA +   G+  D+   A  +V +Y    D  +   +F R++  + + +NS+I +       E  +E +  M    ++  +FT   V+  C+ L     + +GK VH   L+ G E + ++  +L+ MY K   ++ ++ L      RD+ +WN +++       +C  E L                          +AL    EM+ +   V+P+  TI SVLPAC+H   L  G+++H +A + G L+ N  + +AL+ MY  C  +L  R+ F+ +   +  L  WN MI  Y+ +    EA+  F  M   AG+  ++ T  G++  C  SG          + +KR    +  V++   ++D+  R G++  A  +  KM
Sbjct:  113 MELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKG-ELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLS------SLCQNEQLL-------------------------EALEYLREMVLEG--VEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGL--WNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQN--TLMDMYSRLGKIDIAMRIFGKM 466          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKM--TVRDVSSWNAL-----IAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISG-YTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFAS 834
            I  S    + L  G+++HA         D  +G+ +V MYA    L  +  +F ++   + + +N II AY +HG  +E +++   M   G+K +  T+  V   C+    +  G +  + +    G+E        ++++  +   + +A +L + M        +W++L     I   ++ GEI  A++L    P  N+ S   +++  Y+  GL ++A  +   M  K+  V+          P C+    +E G ++H F +
Sbjct:  523 ILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIA-AQNLIQLEP--NVASHYVLLANIYSSAGLWDKATEVRRNM--KEQGVRKE--------PGCSW---IEHGDEVHKFVA 772          

Query:  322 MHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            MH LGL  DNFT PFVLK CA+LSR+ +G+CVHG  L+VGLE D YVG SLI+MYVKC  + DAR+LFDKM VRD++SWNALIAGYMK+GEI +AEDLF +M  RNIVSWTAMISGYTQNG AEQAL LFDEML+  S++KPNWVTI+SVLPACA SAALERGR+IH+FA+ IGL  N S+QTAL  MYAKC SL++AR CF+ +     NL+AWNTMITAYASHG G EAVS FE+M+ AGVQPD +TF GLLSGCSHSGL+D GL +F+ M  ++SVEP VEHYACVVDLLGRAGRL EAK+LI +MPMQAGPS+WGA+L+ACR H NLEIAE+AAR LF+LEP+NSGNYV+LSN+YAEAGMW+EV  LR LLK QG+KK+PGCSW E+NGK+HLF+G D SHPQAKEIY+F L+ LP+KIK AGY+PDTSFVLHD+SEEEKE++LTTHSEKLAIAFGLLNT PGVVLRVTKNLRICGDCH ATK IS+IYEREIIVRDLNRFH FKDG+CSCGDYW
Sbjct:    1 MHFLGLLGDNFTLPFVLKSCADLSRVCMGRCVHGQGLRVGLEGDFYVGASLIDMYVKCGVIGDARKLFDKMIVRDMASWNALIAGYMKEGEIGVAEDLFERMEHRNIVSWTAMISGYTQNGFAEQALGLFDEMLQDGSEMKPNWVTIVSVLPACAQSAALERGRRIHDFANGIGLHLNSSVQTALAGMYAKCYSLVEARCCFDMIAQNGKNLIAWNTMITAYASHGCGVEAVSIFENMLRAGVQPDAVTFMGLLSGCSHSGLIDAGLNHFNDMGTIHSVEPRVEHYACVVDLLGRAGRLVEAKELISQMPMQAGPSVWGALLAACRSHRNLEIAELAARRLFVLEPDNSGNYVLLSNLYAEAGMWEEVKKLRALLKYQGMKKSPGCSWIEINGKSHLFMGADKSHPQAKEIYKF-LEALPEKIKMAGYIPDTSFVLHDISEEEKEYNLTTHSEKLAIAFGLLNTRPGVVLRVTKNLRICGDCHAATKFISKIYEREIIVRDLNRFHCFKDGSCSCGDYW 518          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYAS-------------------------------SDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLG--LKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI-GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDN 1062
            + +S    + + +G+ VH Q    G E D Y+GA ++ MY                                   ++  A  +F R+ + + + + ++I  YT +GF+E+ + ++  M   G  +K +  T   VL  CA+ + +  G+ +H  +  +GL  +  V T+L  MY KC  + +AR  FD +                ++G+  +A              W  MI+ Y  +G   +A+ +F+ ML+  + V+P+ VT M +L  C+HS  ++ G    N    I  +E  V     ++ +  + G L++A++   ++   Q     W  ++ A  SH     A      + V  ++PDN
Sbjct:   16 VLKSCADLSRVCMGRCVHGQGLRVGLEGDFYVGASLIDMYVKCGVIGDARKLFDKMIVRDMASWNALIAGYMKEGEIGVAEDLFERMEHRNIVSWTAMISGYTQNGFAEQALGLFDEMLQDGSEMKPNWVTIVSVLPACAQSAALERGRRIHDFANGIGLHLNSSVQTALAGMYAKCYSLVEARCCFDMIA---------------QNGKNLIA--------------WNTMITAYASHGCGVEAVSIFENMLR--AGVQPDAVTFMGLLSGCSHSGLIDAGLNHFNDMGTIHSVEPRVEHYACVVDLLGRAGRLVEAKELISQM-PMQAGPSVWGALLAACRSHRNLEIAELAARRLFV--LEPDN 348          

Query:  109 QVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            Q+HA +   G +    L  K+   YAS   LD +VA+F R  NPS   + +II  + L G  E+ +  Y +M   G++ + FT+  +LK C     I  GK +H  ++K+G +SD+YV T L+++Y +  D+  A++LFD M  + + S  A++  Y K GE+  A  LF  M  R+ V W  MI GYTQNG+  +AL LF  MLK  +K KPN VT++SVL AC    ALE GR +H++    G++ NV + TAL+ MY+KCGSL DAR  F+++     ++VAWN+MI  YA HG   EA+  F+ M   G+ P NITF G+LS C HSG V  G   F+ MK  Y +EP +EHY C+V+LLGRAG + +A +L+  M ++  P +WG +L ACR H  + + E     L      NSG Y++LSNIYA  G W  V  LR ++K  GVKK PGCS  EVN K H FL G  +HP+ KEIY  +L+E+   +K+ GY P T  VLHD+ E EKE SL  HSEKLAIAFGL+NT PG  +++ KNLR+C DCH  TKLIS+I  R+I+VRD NRFHHF +G+CSCGDYW
Sbjct:   48 QIHAVLFRHGLDHHPILNFKLQRSYASLGRLDYSVALFGRTQNPSVFFWTAIIHGHALRGLHEQALNFYAQMLTQGVEPNAFTFSSILKLCP----IEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLK--AKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKI--DDKDVVAWNSMIVGYAMHGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARLRTMMKDSGVKKEPGCSSIEVNNKVHEFLAGGLNHPKRKEIY-MMLEEINGWLKSHGYTPQTDIVLHDIGETEKERSLEVHSEKLAIAFGLINTQPGTTIKIVKNLRVCADCHEVTKLISKITGRKIVVRDRNRFHHFVNGSCSCGDYW 628          

Query:   46 VSFYAPIF------QSLTGKNLLKL-----GQQVHAQMALRGFEPDAYLG-------------------------------AKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHN-FASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVR--XTQNNLVAWNTMITAYASHGR---GSEAVSTFEDMIVA 1044
            ++FYA +        + T  ++LKL     G+ +H+Q    GF+ D Y+                                  M+  YA   +LD+A  +F  +     + +N +I  YT +G   E + ++ RM     K +  T   VL  C +L  +  G+ VH      G++ +++VGT+L++MY KC  + DAR +FDK+  +DV +WN++I                                GY  +G +++AL LF  M +    + P  +T + +L AC HS  +  G  I N      G+E  +     ++ +  + G +    Q +E V+    + + V W T++ A   HG+   G + V    D  +A
Sbjct:  113 LNFYAQMLTQGVEPNAFTFSSILKLCPIEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLKAKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIV-------------------------------GYAMHGFSQEALQLFKSMCRMG--LHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHV---EQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLA 457          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIV---SWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNF 828
            L+ G+ VH+ +   G + + ++G  +V MY+    L+ A  +F ++++   + +NS+I  Y +HGFS+E ++++  M  +GL   N T+  +L  C     +  G    + +  + G+E  +     ++N+  +   +  A  L   M +  D   W  L+      G+I L E +   +  +N+    ++  + + Y   G  +    L    + KDS VK          P C   +++E   K+H F
Sbjct:  272 LESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIVGYAMHGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARL--RTMMKDSGVKKE--------PGC---SSIEVNNKVHEF 508          

Query:  166 KMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            K+   YAS   LD +VA+F R  NPS   + +II  + L G  E+ +  Y +M   G++ + FT+  +LK C     I  GK +H  ++K+G +SD+YV T L+++Y +  D+  A++LFD M  + + S  A++  Y K GE+  A  LF  M  R+ V W  MI GYTQNG+  +AL LF  MLK  +K KPN VT++SVL AC    ALE GR +H++    G++ NV + TAL+ MY+KCGSL DAR  F+++     ++VAWN+MI  YA  G   EA+  F+ M   G+ P NITF G+LS C HSG V  G   F+ MK  Y +EP +EHY C+V+LLGRAG + +A +L+  M ++  P +WG +L ACR H  + + E     L      NSG Y++LSNIYA  G W  V  LR ++K  GVKK PGCS  EVN K H FL G  +HP+ KEIY  +L+E+   +K+ GY P T  VLHD+ E EKE SL  HSEKLAIAFGL+NT PG  +++ KNLR+C DCH  TKLIS+I  R+I+VRD NRFHHF +G+CSCGDYW
Sbjct:   14 KLQRSYASLGRLDYSVALFGRTQNPSVFFWTAIIHGHALRGLHEQALNFYAQMLTQGVEPNAFTFSSILKLCP----IEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLK--AKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKI--DDKDVVAWNSMIVGYAMXGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARLRTMMKDSGVKKEPGCSSIEVNNKVHEFLAGGLNHPKRKEIY-MMLEEINGWLKSHGYTPQTDIVLHDIGETEKERSLEVHSEKLAIAFGLINTQPGTTIKIVKNLRVCADCHEVTKLISKITGRKIVVRDRNRFHHFVNGSCSCGDYW 575          

Query:   46 VSFYAPIF------QSLTGKNLLKL-----GQQVHAQMALRGFEPDAYLG-------------------------------AKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHN-FASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVR--XTQNNLVAWNTMITAYASHGR---GSEAVSTFEDMIVA 1044
            ++FYA +        + T  ++LKL     G+ +H+Q    GF+ D Y+                                  M+  YA   +LD+A  +F  +     + +N +I  YT +G   E + ++ RM     K +  T   VL  C +L  +  G+ VH      G++ +++VGT+L++MY KC  + DAR +FDK+  +DV +WN++I                                GY   G +++AL LF  M +    + P  +T + +L AC HS  +  G  I N      G+E  +     ++ +  + G +    Q +E V+    + + V W T++ A   HG+   G + V    D  +A
Sbjct:   60 LNFYAQMLTQGVEPNAFTFSSILKLCPIEPGKALHSQAVKLGFDSDLYVRTGLLDVYARGGDVVSAQQLFDTMPEKSLVSLTAMLTCYAKHGELDAARVLFDGMEERDGVCWNVMIDGYTQNGMPNEALVLFRRMLKAKAKPNEVTVLSVLSACGQLGALESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIV-------------------------------GYAMXGFSQEALQLFKSMCRMG--LHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHV---EQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLA 404          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIV---SWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNF 828
            L+ G+ VH+ +   G + + ++G  +V MY+    L+ A  +F ++++   + +NS+I  Y + GFS+E ++++  M  +GL   N T+  +L  C     +  G    + +  + G+E  +     ++N+  +   +  A  L   M +  D   W  L+      G+I L E +   +  +N+    ++  + + Y   G  +    L    + KDS VK          P C   +++E   K+H F
Sbjct:  219 LESGRWVHSYIENNGIQFNVHVGTALVDMYSKCGSLEDARLVFDKIDDKDVVAWNSMIVGYAMXGFSQEALQLFKSMCRMGLHPTNITFIGILSACGHSGWVTEGWDIFNKMKDEYGIEPKIEHYGCMVNLLGRAGHVEQAYELVKNMNIEPDPVLWGTLLGACRLHGKIALGEKIVELLVDQNLANSGTYILLSNIYAAVGNWDGVARL--RTMMKDSGVKKE--------PGC---SSIEVNNKVHEF 455          

Query:   88 NLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVK--------------------------------CC---DMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            N L    Q+HAQ+ L     ++ +  ++++   S   LD A++IF   ++P+  ++N++IR    +   E ++  +  M  L ++ D  T PFVLK  A L  + +G+C+HG  +K+GLE D +V  SL++MYVK                                CC   D+S A  LF+ M  R+  SWN+LI G++++G++  A +LF +MP +N+VSWT MI+G++QNG  E+AL +F  ML++   V+PN +T++S L AC    AL+ G +IHN+ S  G + N  I TAL+ MYAKCG++  A + F  V     +L+ W+ MI  +A HG   +A+  F  M  AG+ PD + F  +L+ CSHSG VD GL +F+ M+  YS+EP ++HY  +VDLLGRAGRL EA   I  MP+     IWGA+  ACR H N+E+AE+ A  L  LEP++ G+YV LSN+YA  G W++V+ +R L+K +GV+K+PG S+ EV G+ H F+ GD +H +A+EI    L+E+    K  GY+P+T++VLH++ EEEKE +L +HSEKLA+AFGL++T+PG  +R+ KNLR+CGDCH+  K  S++  REII+RD+ RFHHFKDG CSCGDYW
Sbjct:   51 NTLPQLHQIHAQIFLHNLFSNSRVVTQLISSSCSLKSLDYALSIFRCFDHPNLFVFNALIRGLAENSRFEGSVSHFVLMLRLSIRPDRLTLPFVLKSVAALVDVGLGRCLHGGVMKLGLEFDSFVRVSLVDMYVKIGELGFGLQLFDESPQRNKAESILLWNVLINGCCKVGDLSKAASLFEAMPERNAGSWNSLINGFVRNGDLDRARELFVQMPEKNVVSWTTMINGFSQNGDHEKALSMFWRMLEEG--VRPNDLTVVSALLACTKIGALQVGERIHNYLSSNGFQLNRGIGTALVDMYAKCGNIKSASRVF--VETKGKDLLTWSVMIWGWAIHGCFDQALQCFVKMKSAGINPDEVIFLAILTACSHSGNVDQGLNFFESMRLDYSIEPTMKHYTLIVDLLGRAGRLDEALSFIQSMPINPDFVIWGALFCACRAHKNIEMAELTAEKLLQLEPKHPGSYVFLSNVYAAVGRWEDVERVRTLMKNRGVEKDPGWSYIEVEGQVHSFVAGDHAHVRAEEI-SLKLEEITASAKQEGYMPETAWVLHNIEEEEKEDALGSHSEKLALAFGLISTAPGSTIRIVKNLRVCGDCHSMMKYASKLSRREIILRDIKRFHHFKDGTCSCGDYW 677          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNI---------------------------------------VSWTAMISGYTQNGLAEQALFLFDEMLKKD-----------------------------SKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +  + ++   ++ L+ G++VH  +  RGFE D  +G  + +MY     L++A  +F R+     + +N+II  Y+ +G   E + ++  M   G+K ++ T   V+  CA L  +  GK +H  +++ G+ESD+ V   L+NMY KC +++ A +LF++M +RDV+SWNA+I GY  + +   A   F +M  R I                                       V   A+++ Y + G    A  LF+ M KK+                               +KP+   I+SVLPACAH  ALE+G++IH +  R G ESNV + T L+ +YAKCG++  A++ FER+   + ++V+W TMI AY  HG G +A++ F  M   G + D+I FT +L+ CSH+GLVD GL+YF  MK  Y + P +EHYAC+VDLLGRAG L EA  +I  M ++   ++WGA+L ACR H N+E+ E AA+ LF L+P+N+G YV+LSNIYAEA  W++V  LR ++K +GVKK PGCS   V+     FL GD +HPQ+++IY  +L+ L ++++ AGYVP+T+  L DV EE KE+ L++HSEKLAI+FG++NTSPG+ +R+ KNLR+C DCH ATK IS+I  REIIVRD NRFHH K+G CSCGDYW
Sbjct:  123 FLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQVFDRMPKRDVVSWNAIIAGYSQNGQPYEALALFSEMQVNGIKPNSSTLVSVMPVCAHLLALEQGKQIHCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPIRDVASWNAIIGGYSLNSQHHEALAFFNRMQVRGIKPNSITMVSVLPACAHLFALEQGQQIHGYAIRSGFESNDVVGNALVNMYAKCGNVNSAYKLFERMPKKNVVAWNAIISGYSQHGHPHEALALFIEMQAQGIKPDSFAIVSVLPACAHFLALEQGKQIHGYTIRSGFESNVVVGTGLVDIYAKCGNVNTAQKLFERM--PEQDVVSWTTMILAYGIHGHGEDALALFSKMQETGTKLDHIAFTAILTACSHAGLVDQGLQYFQCMKSDYGLAPKLEHYACLVDLLGRAGHLDEANGIIKNMSLEPDANVWGALLGACRIHCNIELGEQAAKHLFELDPDNAGYYVLLSNIYAEAQRWEDVAKLRKMMKEKGVKKQPGCSVVAVHRDVQTFLVGDRTHPQSEQIYA-MLEILYEQMRKAGYVPNTNLALQDVEEEAKENILSSHSEKLAISFGIINTSPGIPIRIMKNLRVCSDCHNATKFISKIVGREIIVRDANRFHHVKNGFCSCGDYW 795          

Query:  241 STLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            + +++   I  Y  +GF  + + +Y +M   G+  D   +  V+K C   S +  G+ VH   +  G ESD+ VGT+L +MY KC  + +AR+                               +F +MP R++VSW A+I+GY+QNG   +AL LF EM  + + +KPN  T++SV+P CAH  ALE+G++IH +A R G+ES+V +   L+ MYAKCG++  A + FER+     ++ +WN +I  Y+ + +  EA++ F  M V G++P++IT   +L  C+H   ++ G +   Y  R       V   A +V++  + G +  A  L  +MP +     W A++S   +H
Sbjct:   84 NAVVWKETIIGYVKNGFWNKALRLYYQMQRTGINPDKLVFLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQ-------------------------------VFDRMPKRDVVSWNAIIAGYSQNGQPYEALALFSEM--QVNGIKPNSSTLVSVMPVCAHLLALEQGKQIHCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPI--RDVASWNAIIGGYSLNSQHHEALAFFNRMQVRGIKPNSITMVSVLPACAHLFALEQGQQIHGYAIRSGFESNDVVGNA-LVNMYAKCGNVNSAYKLFERMP-KKNVVAWNAIISGYSQH 401          

Query:  637 NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACV----VDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAML---SACRKHH 1308
            N V W   I GY +NG   +AL L+ +M +  + + P+ +  +SV+ AC   + L+ GRK+H      G ES+V + TAL +MY KCGSL +ARQ F+R+   + ++V+WN +I  Y+ +G+  EA++ F +M V G++P++ T   ++  C+H   ++ G +        Y++  G+E    V    V++  + G +  A  L  +MP++   S W A++   S   +HH
Sbjct:   84 NAVVWKETIIGYVKNGFWNKALRLYYQMQR--TGINPDKLVFLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQVFDRM--PKRDVVSWNAIIAGYSQNGQPYEALALFSEMQVNGIKPNSSTLVSVMPVCAHLLALEQGKQI-----HCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPIRDVAS-WNAIIGGYSLNSQHH 304          

Query:   70 QSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMV-------AMYASSDDLDSAVAIFHRVNN----PSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            ++  G + LK  +QVH   ++ GF+ D+++ + +V       A YA    +D A  +F  + +    P+ + +N +I  +   G   E + ++  MH  G + D  T   VL    +L  + +G  +HG  +K GL SD  V ++LI+MY KC   S+  ++FD+M   DV S NA I G  ++G++  +  LF ++  +    N+VSWT+MI+  +QNG   +AL LF EM  + + VKPN VTI  +LPAC + AAL  G+  H F+ R G+ ++V + +AL+ MYAKCG +  +R CF+ +     NLV WN +I  YA HG+  EA+  F+ M  +G +PD I+FT +LS CS SGL + G  YF+ M   Y +E  VEHYAC+V LL RAG+L +A  +I +MP+     +WGA+LS+CR H+N+ + E+AA  LF LEP N GNY++LSNIYA  GMW EV+ +R ++K +G++KNPGCSW EV  K H+ L GD SHPQ  +I E  LD+L  ++K  GY P+ +FVL DV E++KE  L  HSEKLA+ FGLLNT PG  L+V KNLRICGDCH   K IS    REI VRD NRFHHFK+G CSCGDYW
Sbjct:  122 KACAGLSALKPARQVHGIASVSGFDSDSFVQSSLVHIWSALVAAYARQGCVDEAKRLFSEMGDSGVQPNLISWNGMIAGFNHSGLYSEAVLMFLDMHLRGFEPDGTTISSVLPAVGDLEDLVMGILIHGYVIKQGLVSDKCVSSALIDMYGKCSCTSEMSQVFDQMDHMDVGSCNAFIFGLSRNGQVESSLRLFRQLKDQGMELNVVSWTSMIACCSQNGRDIEALELFREM--QIAGVKPNSVTIPCLLPACGNIAALMHGKAAHCFSLRRGISTDVYVGSALIDMYAKCGRIQASRICFDGI--PTKNLVCWNAVIAGYAMHGKAKEAMEIFDLMQRSGQKPDIISFTCVLSACSQSGLTEEGSYYFNSMSSKYGIEARVEHYACMVTLLSRAGKLEQAYAMIRRMPVNPDACVWGALLSSCRVHNNVSLGEVAAEKLFELEPSNPGNYILLSNIYASKGMWNEVNRVRDMMKNKGLRKNPGCSWIEVKNKVHMLLAGDKSHPQMTQIIE-KLDKLSMEMKKLGYFPEINFVLQDVEEQDKEQILCGHSEKLAVVFGLLNTPPGYPLQVIKNLRICGDCHVVIKFISSFERREIFVRDTNRFHHFKEGACSCGDYW 734          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERV---------------------------------RXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH----HNLEIAEIAARS 1341
            +Q HA +   G   D +L  K+++ YA++     A  +   V  P+   ++++I A++        +  + +M   GL  DN   P  +K CA LS +   + VHG++   G +SD +V +SL+++                        W+AL+A Y + G +  A+ LF +M       N++SW  MI+G+  +GL  +A+ +F +M  +    +P+  TI SVLPA      L  G  IH +  + GL S+  + +AL+ MY KC    +  Q F+++                                 +  + N+V+W +MI   + +GR  EA+  F +M +AGV+P+++T   LL  C +   +  G     +  R   +   V   + ++D+  + GR+  ++     +P +     W A+++    H      +EI ++  RS
Sbjct:   33 RQAHAHILKTGLFNDTHLATKLLSHYANNMCFADATLVLDLVPEPNVFSFSTLIYAFSKFHQFHHALSTFSQMLTRGLMPDNRVLPSAVKACAGLSALKPARQVHGIASVSGFDSDSFVQSSLVHI------------------------WSALVAAYARQGCVDEAKRLFSEMGDSGVQPNLISWNGMIAGFNHSGLYSEAVLMFLDMHLRG--FEPDGTTISSVLPAVGDLEDLVMGILIHGYVIKQGLVSDKCVSSALIDMYGKCSCTSEMSQVFDQMDHMDVGSCNAFIFGLSRNGQVESSLRLFRQLKDQGMELNVVSWTSMIACCSQNGRDIEALELFREMQIAGVKPNSVTIPCLLPACGNIAALMHGKAAHCFSLR-RGISTDVYVGSALIDMYAKCGRIQASRICFDGIPTK-NLVCWNAVIAGYAMHGKAKEAMEIFDLMQRS 457          

Query:   82 GKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGK-------MPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            G N LK  + VHA +   G + D+YL  K++    +  + + +  IFH+   P+  L+N++I    L+   +E++EIY  M   GL  D+FT+PF+LK CA L    +G  +HGL +K G ESD +V TSL+++Y KC  + +A ++FD +  ++V++W A+I+GY+  G+   A D+F +       M  ++IVSW++MI GY  NGL ++AL LF +ML +    +P+   ++ VL ACA   ALE G    N   R     N  + TAL+ MYAKCG +  A + F  +R  + ++V WN  I+  A  G    A   F  M  +G++PD  TF GLL  C+H+GLVD G +YF+ M+RV+++ P +EHY C+VDLLGRAG L EA  L+  MPM+A   +WGA+L  CR H + ++ E   + L  LEP NSGNYV+LSNIY+ +  W++   +R ++  +G+KK PG SW EV+G  H FL GDTSHP +++IY   L EL K +KA+GYVP T +VL D+ EEEKEH +  HSEKLAIAFGL++T+P   +RV KNLR+CGDCH A K ISR   REIIVRD NRFH F DG+CSC DYW
Sbjct:   19 GFNSLKHLKHVHAALLRLGLDEDSYLLNKVLRFSFNFGNTNYSHRIFHQTKEPNIFLFNTMIHGLVLNDSFQESIEIYHSMRKEGLSPDSFTFPFLLKACARLLDSKLGIKLHGLVVKAGCESDAFVNTSLVSLYGKCGFIDNAFKVFDDIPEKNVAAWTAIISGYIGVGKCREAIDMFRRACSVFDGMLEKDIVSWSSMIQGYASNGLPKEALDLFFKMLNEG--FRPDCYAMVGVLCACARLGALELGNWASNLMDRNEFLGNPVLGTALIDMYAKCGRMDSAWEVFRGMR--KKDIVVWNAAISGLAMSGHVKAAFGLFGQMEKSGIEPDGNTFVGLLCACTHAGLVDEGRQYFNSMERVFTLTPEIEHYGCMVDLLGRAGFLDEAHQLVKSMPMEANAIVWGALLGGCRLHRDTQLVEGVLKQLIALEPSNSGNYVLLSNIYSASHKWEDAAKIRSIMSERGIKKVPGYSWIEVDGVVHEFLVGDTSHPLSEKIYA-KLGELVKDLKASGYVPTTDYVLFDIEEEEKEHFIGCHSEKLAIAFGLISTAPNDKIRVVKNLRVCGDCHEAIKHISRFTGREIIVRDNNRFHCFNDGSCSCKDYW 619          

Query:  334 GLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            G+K + FT   V+K CA ++ +  GK  H   +K+G ESD+ V T+L++MY +C  + DA  +FDKM+ R   +WNA+I G+ ++ ++  A  LF +M  R++VSWTA+I+GY QNG  +++L +F++M K  + +K +   + SVL ACA  AALE GR+ H +  + G   ++ + +AL+ MYAK GS+ DA Q F+++   Q N V+WN++IT  A HGRG++AV  FE M+ AG++P+ I+F G+LS CSH+GLV+ G  YF+ M + Y + P V HY C++DLLGRAG L EA++ I  MP++   S+WGA+L ACR H N E+A+  A  L  +E + +G YV+LSNIYA AG W +   +R L+K +GV K PG SW EV    H F+ G+TSHPQ KEI+EF L+ L +K+KAAGYVP+ +FVL DV ++EKE SL+ HSEKLAIAFG++NT+PG  +RV KNLR+CGDCHT  K IS  + R+I+VRD NRFHHFKDG CSCGDYW
Sbjct:    5 GVKPNQFTLSTVVKACASIASLEQGKQAHNYIIKMGFESDVVVQTALVHMYARCGSLEDAGHVFDKMSERSTRTWNAMITGHAQNRDMKKALKLFYEMSERDVVSWTAVIAGYAQNGYGDESLNVFNQMRK--TGMKSDRFIMGSVLSACADLAALELGRQFHAYVVQSGFALDIVVGSALVDMYAKSGSMEDACQVFDKM--PQRNEVSWNSIITGCAQHGRGNDAVLLFEQMLQAGIKPNEISFVGVLSACSHTGLVNEGRGYFNLMTQNYGIVPDVSHYTCMIDLLGRAGCLDEAENFINGMPVEPDVSVWGALLGACRIHGNTELAKRIAEHLLGMEVQIAGIYVLLSNIYAAAGQWDDAAKVRKLMKDRGVMKQPGYSWIEVKTIMHAFVAGETSHPQLKEIHEF-LESLSRKMKAAGYVPNKNFVLQDVEDDEKELSLSHHSEKLAIAFGIINTNPGTTIRVAKNLRVCGDCHTVIKFISLNFTRKIVVRDANRFHHFKDGRCSCGDYW 514          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYN-------------------------------SIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASR-IGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQ 1053
            L+ G+Q H  +   GFE D  +   +V MYA    L+ A  +F +++  ST  +N                               ++I  Y  +G+ +E++ ++ +M   G+K D F    VL  CA+L+ + +G+  H   ++ G   D+ VG++L++MY K   M DA ++FDKM  R+  SWN++                               I+G  Q+G    A+ LF++ML+  + +KPN ++ + VL AC+H+  +  GR   N  ++  G+  +VS  T ++ +  + G  LD  + F      + ++  W  ++ A   HG    A    E ++   VQ
Sbjct:   26 LEQGKQAHNYIIKMGFESDVVVQTALVHMYARCGSLEDAGHVFDKMSERSTRTWNAMITGHAQNRDMKKALKLFYEMSERDVVSWTAVIAGYAQNGYGDESLNVFNQMRKTGMKSDRFIMGSVLSACADLAALELGRQFHAYVVQSGFALDIVVGSALVDMYAKSGSMEDACQVFDKMPQRNEVSWNSI-------------------------------ITGCAQHGRGNDAVLLFEQMLQ--AGIKPNEISFVGVLSACSHTGLVNEGRGYFNLMTQNYGIVPDVSHYTCMIDLLGRAG-CLDEAENFINGMPVEPDVSVWGALLGACRIHGNTELAKRIAEHLLGMEVQ 343          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGL-SLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIV---SWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKP--NWVTIMSVLPA-CAHSAALERGRKIHNF 828
            L+LG+Q HA +   GF  D  +G+ +V MYA S  ++ A  +F ++   + + +NSII     HG   + + ++ +M   G+K +  ++  VL  C+    +  G+    L +   G+  D+   T +I++  +   + +A    + M V  DVS W AL+      G   LA+ +   + G  +     +  + + Y   G  + A  +   M  +    +P  +W+ + +++ A  A   +  + ++IH F
Sbjct:  158 LELGRQFHAYVVQSGFALDIVVGSALVDMYAKSGSMEDACQVFDKMPQRNEVSWNSIITGCAQHGRGNDAVLLFEQMLQAGIKPNEISFVGVLSACSHTGLVNEGRGYFNLMTQNYGIVPDVSHYTCMIDLLGRAGCLDEAENFINGMPVEPDVSVWGALLGACRIHGNTELAKRIAEHLLGMEVQIAGIYVLLSNIYAAAGQWDDAAKVRKLMKDRGVMKQPGYSWIEVKTIMHAFVAGETSHPQLKEIHEF 410          

Query:   22 LLAQDPRFVSFYAPIFQSLTGKNL-----LKLGQQVHAQMAL-RGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGE-------------------------------------ICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            L  Q P+    +  + + L  K L      K  +++H+++ + +   P+  LG K++  YA+  +      IF  + + + + +N +IR+Y  +G  ++ + ++  M   G   DN+TYP VLK C+    +W+G  +HG  +K+GL+ ++Y+G  L++MY KC  +  ARR+ D+M  RD+ SWN+++AGY ++G                                      +   +D+F K+  ++++SW  MI+ Y  N +  +A+ L+ +M  +   V+P+ V+I SVLPAC   +A   GR+IH +  R  L  N+ ++ AL+ MYAKCG L +AR  F+++     ++V+W +MI+AY   G+G +AV+ F+ M  +G  PD I F  +L+ CSH+GLVD G   F+ M   Y + PG+EHY C+VDLLGRAG++ EA  L  +MPM+    +WG++LSACR + ++ IA +AA  LF L PE SG YV+LSNIYA+AG W++V+ +R ++ ++G+KK PG S  E+N   + FL GD SH Q+KEIY+  L  L  ++K  GY+P+T   LHDV EE+KE  L  HSEKLAI F +LNT PG  +R+TKN+R+CGDCH ATKLIS+I EREII+RD +RFHHF+DG CSCGDYW
Sbjct:   22 LTTQKPQLSPKFTALTEDLCNKILDVNPDAKTLKKLHSKILIDQNLHPNPSLGIKLMRAYAACGEPCYTRHIFDEITDKNVVFFNVMIRSYVNNGLYQDALLVFKTMANQGFYPDNYTYPCVLKACSVSGNLWVGLQIHGAVVKLGLDMNLYIGNGLVSMYGKCKWLDAARRVLDEMPGRDMVSWNSMVAGYAQNGRFNDALKLCREMEDLKLKPDAGTMGSLLPAVTNTSCDNVLYVKDMFVKLKEKSLISWNVMIAVYVNNAMPNEAVDLYLQM--QVHGVEPDAVSISSVLPACGDLSAAVLGRRIHEYVERKKLRPNLLLENALIDMYAKCGCLKEARAVFDQMMF--RDVVSWTSMISAYGMSGQGKDAVALFKKMRDSGFTPDWIAFVSVLAACSHAGLVDEGRYCFNLMAE-YGITPGIEHYNCMVDLLGRAGKIDEAYHLTRQMPMEPNERVWGSLLSACRVYSSMNIALLAADHLFQLAPEQSGYYVLLSNIYAKAGRWQDVETVRSIMNSKGIKKIPGNSNVEINDHVYTFLAGDQSHTQSKEIYK-ALGVLVGRMKELGYMPETDSALHDVEEEDKECHLAVHSEKLAIVFAILNTKPGSTIRITKNIRVCGDCHVATKLISKIAEREIIIRDTHRFHHFRDGVCSCGDYW 677          

Query:   49 SFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            S YA + QS   +  +K G+Q+HAQ+ L GF  D  +  K+V +Y   D L SA  +F R+   +  L+N +IR Y  +G  E  +++Y +M   GL  DNFT+PFVLK CA LS I  G+ +H   ++ G E D++VG +LI+MY KC                               G +  A ++F K+  R+ V W +M++ Y+QNG  +  L L  EM+   + ++P   T+++ + A A +AAL +GR++H  + R   ES+  ++TAL+ MYAKCGS+  AR  FER+   +  +V+WN MIT YA HG  +EA+  FE+M     +PD+ITF G+LS CSH GL++ G  +F+ M R Y ++P V+HY C+VDLLG +GRL EA +LI +M +     +WGA+L++C+ H N+E+ EIA   L  LEP+++GNYV+LSNIYA+AG W+ V  LR L+  + +KK+  CSW EV  K H FL GDTSHP + EIY   L+ +   +K AGY P T  V HDV ++EK + + +HSE+LAIAFGL++T PG  L +TKNLRIC DCH A K IS+I EREI VRD+NR+HHFKDG CSCGDYW
Sbjct:   76 SNYASLLQSCIARKAIKPGKQLHAQVCLAGFGFDTVIATKLVNLYCVCDSLSSARLLFDRIPKHNIFLWNVLIRGYAWNGPYEAAVQLYYQMFDYGLVPDNFTFPFVLKACAALSAIEHGREIHEHVVQTGWEKDVFVGAALIDMYAKC-------------------------------GCVGSAREVFDKILVRDAVLWNSMLAAYSQNGHPDACLSLCSEMVL--TGLRPTEATLVTAISASADNAALPQGRELHGLSWRQEFESHDKVKTALVDMYAKCGSVRVARNLFERLGVKR--VVSWNAMITGYAMHGHATEALDLFEEMNRVA-KPDHITFVGVLSACSHGGLLEEGWMFFETMIRDYKIDPTVQHYTCMVDLLGHSGRLDEAYNLIMQMKVLPDSGVWGALLNSCKIHANVELGEIALERLIELEPDDAGNYVILSNIYAQAGKWEGVAKLRKLMTDRRLKKSIACSWIEVKNKVHAFLSGDTSHPLSDEIYS-ELERVGGLMKEAGYSPSTGSVFHDVEDDEKANMVCSHSERLAIAFGLISTPPGTRLLITKNLRICEDCHVAIKFISKITEREITVRDVNRYHHFKDGVCSCGDYW 648          

Query:  745 PNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSA 1293
            P +    S+L +C    A++ G+++H      G   +  I T L+ +Y  C SL  AR  F+R+   ++N+  WN +I  YA +G    AV  +  M   G+ PDN TF  +L  C+    ++ G +  +++ +    E  V   A ++D+  + G +  A+++  K+ +     +W +ML+A
Sbjct:   73 PTYSNYASLLQSCIARKAIKPGKQLHAQVCLAGFGFDTVIATKLVNLYCVCDSLSSARLLFDRI--PKHNIFLWNVLIRGYAWNGPYEAAVQLYYQMFDYGLVPDNFTFPFVLKACAALSAIEHGREIHEHVVQT-GWEKDVFVGAALIDMYAKCGCVGSAREVFDKI-LVRDAVLWNSMLAA 251          

Query:  112 VHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDG------EIC-------------------------------LAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNT-----SPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            VH+++ L     ++ LG K++  YAS  D+ SA  +F  +   + ++ N +IR+Y  +GF  E ++++G M    ++ D++T+P VLK C+    I IG+ +HG + KVGL S ++VG  L++MY KC  +S+AR + D+M+ RDV SWN+L+ GY ++       E+C                                 +D+F KM  +++VSW  MI  Y +N +  +A+ L+  M  +    +P+ V+I SVLPAC  ++AL  G+KIH +  R  L  N+ ++ AL+ MYAKCG L  AR  FE ++    ++V+W  MI+AY   GRG +AV+ F  +  +G+ PD+I F   L+ CSH+GL++ G   F  M   Y + P +EH AC+VDLLGRAG++ EA   I  M M+    +WGA+L ACR H + +I  +AA  LF L PE SG YV+LSNIYA+AG W+EV N+R ++K++G+KKNPG S  EVN   H FL GD SHPQ+ EIY   LD L KK+K  GYVPD+   LHDV EE+KE  L  HSEKLAI F L+NT          +R+TKNLRICGDCH A KLIS+I  REII+RD NRFH F+ G CSCGDYW
Sbjct:   61 VHSRIILEDLRCNSSLGVKLMRAYASLKDVASARKVFDEIPERNVIIINVMIRSYVNNGFYGEGVKVFGTMCGCNVRPDHYTFPCVLKACSCSGTIVIGRKIHGSATKVGLSSTLFVGNGLVSMYGKCGFLSEARLVLDEMSRRDVVSWNSLVVGYAQNQRFDDALEVCREMESVKISHDAGTMASLLPAVSNTTTENVMYVKDMFFKMGKKSLVSWNVMIGVYMKNAMPVEAVELYSRM--EADGFEPDAVSITSVLPACGDTSALSLGKKIHGYIERKKLIPNLLLENALIDMYAKCGCLEKARDVFENMK--SRDVVSWTAMISAYGFSGRGCDAVALFSKLQDSGLVPDSIAFVTTLAACSHAGLLEEGRSCFKLMTDHYKITPRLEHLACMVDLLGRAGKVKEAYRFIQDMSMEPNERVWGALLGACRVHSDTDIGLLAADKLFQLAPEQSGYYVLLSNIYAKAGRWEEVTNIRNIMKSKGLKKNPGASNVEVNRIIHTFLVGDRSHPQSDEIYR-ELDVLVKKMKELGYVPDSESALHDVEEEDKETHLAVHSEKLAIVFALMNTKEEEEDSNNTIRITKNLRICGDCHVAAKLISQITSREIIIRDTNRFHVFRFGVCSCGDYW 686          

Query:  811 RKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAM-------------LSACRKHHNLEIAEIAARSLFIL 1353
            R +H+      L  N S+   L+  YA    +  AR+ F+ +   + N++  N MI +Y ++G   E V  F  M    V+PD+ TF  +L  CS SG + +G K      +V  +   +     +V + G+ G L+EA+ ++ +M  +   S W ++             L  CR+  +++I+  A     +L
Sbjct:   59 RTVHSRIILEDLRCNSSLGVKLMRAYASLKDVASARKVFDEI--PERNVIIINVMIRSYVNNGFYGEGVKVFGTMCGCNVRPDHYTFPCVLKACSCSGTIVIGRKIHGSATKV-GLSSTLFVGNGLVSMYGKCGFLSEARLVLDEMSRRDVVS-WNSLVVGYAQNQRFDDALEVCREMESVKISHDAGTMASLL 248          

Query:  109 QVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAE----LSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +VH  +   G + D +L  K++ MY+    +D A  +F +    +  ++N++ RA TL G  EE + +Y +M+ +G++ D FTY +VLK C      ++ +  GK +H    + G  S +Y+ T+L++MY +                                G +  A  +FG MP RN+VSW+AMI+ Y +NG A +AL  F EM+++     PN VT++SVL ACA  AALE+G+ IH +  R GL+S + + +AL+ MY +CG L   ++ F+R+     ++V+WN++I++Y  HG G +A+  FE+M+  G  P  +TF  +L  CSH GLV+ G + F+ M R + ++P +EHYAC+VDLLGRA RL EA  ++  M  + GP +WG++L +CR H N+E+AE A+R LF LEP+N+GNYV+L++IYAEA MW EV  ++ LL+ +G++K PG  W EV  K + F+  D  +P  ++I+ FL+ +L + +K  GY+P T  VL+++  EEKE  +  HSEKLA+AFGL+NTS G  +R+TKNLR+C DCH  TK IS+  E+EI+VRD+NRFH FK+G CSCGDYW
Sbjct:   98 RVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTRKRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIGVESDRFTYTYVLKACVASECTVNHLMKGKEIHAHLTRRGYSSHVYIMTTLVDMYARF-------------------------------GCVDYASYVFGGMPVRNVVSWSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSVLQACASLAALEQGKLIHGYILRRGLDSILPVISALVTMYGRCGKLEVGQRVFDRMH--DRDVVSWNSLISSYGVHGYGKKAIQIFEEMLANGASPTPVTFVSVLGACSHEGLVEEGKRLFETMWRDHGIKPQIEHYACMVDLLGRANRLDEAAKMVQDMRTEPGPKVWGSLLGSCRIHGNVELAERASRRLFALEPKNAGNYVLLADIYAEAQMWDEVKRVKKLLEHRGLQKLPGRCWMEVRRKMYSFVSVDEFNPLMEQIHAFLV-KLAEDMKEKGYIPQTKGVLYELETEEKERIVLGHSEKLALAFGLINTSKGEPIRITKNLRLCEDCHLFTKFISKFMEKEILVRDVNRFHRFKNGVCSCGDYW 657          

Query:   88 NLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM--HCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASR-IGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHG 999
            N L  G+++HA +  RG+    Y+   +V MYA    +D A  +F  +   + + ++++I  Y  +G + E +  +  M         ++ T   VL+ CA L+ +  GK +HG  L+ GL+S + V ++L+ MY +C  +   +R+FD+M  RDV SWN+L                               IS Y  +G  ++A+ +F+EML   +   P  VT +SVL AC+H   +E G+++     R  G++  +     ++ +  +   L +A +  + +R T+     W +++ +   HG
Sbjct:  196 NHLMKGKEIHAHLTRRGYSSHVYIMTTLVDMYARFGCVDYASYVFGGMPVRNVVSWSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSVLQACASLAALEQGKLIHGYILRRGLDSILPVISALVTMYGRCGKLEVGQRVFDRMHDRDVVSWNSL-------------------------------ISSYGVHGYGKKAIQIFEEMLANGASPTP--VTFVSVLGACSHEGLVEEGKRLFETMWRDHGIKPQIEHYACMVDLLGRANRLDEAAKMVQDMR-TEPGPKVWGSLLGSCRIHG 468          

Query:  643 VSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLL-----SGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNI 1395
            +S   +I    + G  +QA+     +L ++S   P+  T   ++  C H ++L    ++H      G + +  + T L+ MY+  GS+  AR+ F++ R  +  +  WN +  A    G G E +  +  M   GV+ D  T+T +L     S C+ + L+     +    +R YS    V     +VD+  R G +  A  +   MP++   S W AM++   K+     A    R +     ++S N V + ++
Sbjct:   47 ISNNQLIQSLCKEGKLKQAI----RVLSQESS--PSQQTYELLILCCGHRSSLSDALRVHRHILDNGSDQDPFLATKLIGMYSDLGSVDYARKVFDKTR--KRTIYVWNALFRALTLAGHGEEVLGLYWKMNRIGVESDRFTYTYVLKACVASECTVNHLMKGKEIHAHLTRRGYSSH--VYIMTTLVDMYARFGCVDYASYVFGGMPVRNVVS-WSAMIACYAKNGKAFEALRTFREMMRETKDSSPNSVTMVSV 291          

Query:    4 RTLLKPLLAQDPRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLK-VGLESDMYVGTSLINMYVKCCDMSDARRLF-DKMTVRDVSSWNALIAGYMKDGEICLAE 609
            R +++      P  V+  + + Q+      L+ G+ +H  +  RG +    + + +V MY     L+    +F R+++   + +NS+I +Y +HG+ ++ ++I+  M   G      T+  VL  C+    +  GK +     +  G++  +     ++++  +   + +A ++  D  T      W +L+      G + LAE
Sbjct:  272 REMMRETKDSSPNSVTMVS-VLQACASLAALEQGKLIHGYILRRGLDSILPVISALVTMYGRCGKLEVGQRVFDRMHDRDVVSWNSLISSYGVHGYGKKAIQIFEEMLANGASPTPVTFVSVLGACSHEGLVEEGKRLFETMWRDHGIKPQIEHYACMVDLLGRANRLDEAAKMVQDMRTEPGPKVWGSLLGSCRIHGNVELAE 474          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNP-----STLL------------------------------YNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +F+     +  K+G+Q+H    + G + DA++   M  MY     +  A  +F R+++      S LL                              +N I+  +   G+ +E + ++ ++H LG   D  T   VL    +   + +G+ +HG  +K GL  D  V +++I+MY K   +     LF++  + +    NA I G  ++G +  A ++F     +    N+VSWT++I+G  QNG   +AL LF EM  + + VKPN VTI S+LPAC + AAL  GR  H FA R+ L  NV + +AL+ MYAKCG +  ++  F  +     NLV WN+++  ++ HG+  E +S FE ++   ++PD I+FT LLS C   GL D G KYF  M   Y ++P +EHY+C+V+LLGRAG+L EA DLI +MP +    +WGA+L++CR  +N+++AEIAA  LF LEPEN G YV+LSNIYA  GMW EVD++R  +++ G+KKNPGCSW +V  + +  L GD SHPQ  +I E  +DE+ K+++ +G+ P+  F LHDV E+E+E  L  HSEKLA+ FGLLNT  G  L+V KNLRICGDCH   K IS    REI +RD NRFHHFKDG CSCGD+W
Sbjct:  122 LFKVCAELSAFKVGKQIHCVSCVSGLDMDAFVQGSMFHMYMRCGRMGDARKVFDRMSDKDVVTCSALLCAYARKGCLEEVVRILSEMESSGIEANIVSWNGILSGFNRSGYHKEAVVMFQKIHHLGFCPDQVTVSSVLPSVGDSEMLNMGRLIHGYVIKQGLLKDKCVISAMIDMYGKSGHVYGIISLFNQFEMMEAGVCNAYITGLSRNGLVDKALEMFELFKEQTMELNVVSWTSIIAGCAQNGKDIEALELFREM--QVAGVKPNHVTIPSMLPACGNIAALGHGRSTHGFAVRVHLLDNVHVGSALIDMYAKCGRINLSQIVFNMM--PTKNLVCWNSLMNGFSMHGKAKEVMSIFESLMRTRLKPDFISFTSLLSACGQVGLTDEGWKYFKMMSEEYGIKPRLEHYSCMVNLLGRAGKLQEAYDLIKEMPFEPDSCVWGALLNSCRLQNNVDLAEIAAEKLFHLEPENPGTYVLLSNIYAAKGMWTEVDSIRNKMESLGLKKNPGCSWIQVKNRVYTLLAGDKSHPQIDQITE-KMDEISKEMRKSGHRPNLDFALHDVEEQEQEQMLWGHSEKLAVVFGLLNTPDGTPLQVIKNLRICGDCHAVIKFISSYAGREIFIRDTNRFHHFKDGICSCGDFW 760          

Query:  109 QVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAE--DLFGKMPG----RNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCG------------SLLDARQC-------------------FE--RVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            Q HA++   G + D Y+ AK++A Y++ +  + A  +   + +P+   ++S+I A T      +++ ++ RM   GL  D+   P + K CAELS   +GK +H +S   GL+ D +V  S+ +MY++C  M DAR++FD+M+ +DV + +AL+  Y + G  CL E   +  +M       NIVSW  ++SG+ ++G  ++A+ +F ++        P+ VT+ SVLP+   S  L  GR IH +  + GL  +  + +A++ MY K G             +++A  C                   FE  + +  + N+V+W ++I   A +G+  EA+  F +M VAGV+P+++T   +L  C +   +  G     +  RV+ ++  V   + ++D+  + GR+  ++ +   MP +     W ++++    H
Sbjct:   36 QAHARILKSGAQNDGYISAKLIASYSNYNCFNDADLVLQSIPDPTIYSFSSLIYALTKAKLFTQSIGVFSRMFSHGLIPDSHVLPNLFKVCAELSAFKVGKQIHCVSCVSGLDMDAFVQGSMFHMYMRCGRMGDARKVFDRMSDKDVVTCSALLCAYARKG--CLEEVVRILSEMESSGIEANIVSWNGILSGFNRSGYHKEAVVMFQKI--HHLGFCPDQVTVSSVLPSVGDSEMLNMGRLIHGYVIKQGLLKDKCVISAMIDMYGKSGHVYGIISLFNQFEMMEAGVCNAYITGLSRNGLVDKALEMFELFKEQTMELNVVSWTSIIAGCAQNGKDIEALELFREMQVAGVKPNHVTIPSMLPACGNIAALGHGRSTHGFAVRVHLLD-NVHVGSALIDMYAKCGRINLSQIVFNMMPTK-NLVCWNSLMNGFSMH 467          

Query:  232 NNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDV-SEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +N   + YN++I  Y   GF +E +E+  RM   G++ D FTYP V++ CA    + +GK VH   L+   +   +   SL+++Y KC    +AR +F+KM  +D+ SWNAL++GY+  G I  A+ +F +M  +NI+SW  MISG  +NG  E+ L LF  M  K    +P        + +CA   A   G++ H    +IG +S++S   AL+ MYAKCG + +ARQ F  +    +  V+WN +I A   HG G+EAV  +E+M+  G++PD IT   +L+ CSH+GLVD G KYFD M+ VY + PG +HYA ++DLL R+G+ ++A+ +I  +P +    IW A+LS CR H N+E+  IAA  LF L PE+ G Y++LSN++A  G W+EV  +R L++ +GVKK   CSW E+  + H FL  DTSHP+A+ +Y +L D L K+++  GYVPDTSFVLHDV S+  KE  LTTHSEK+A+AFGL+   PG  +R+ KNLR CGDCH   + +S + +R+II+RD  RFHHF++G CSCG++W
Sbjct:  247 DNMKLVAYNAMISGYVNRGFYQEALEMVRRMVSSGIELDEFTYPSVIRACATAGLLQLGKQVHAYVLRRE-DFSFHFDNSLVSLYYKCGKFDEARAIFEKMPAKDLVSWNALLSGYVSSGHIGEAKLIFKEMKEKNILSWMIMISGLAENGFGEEGLKLFSCM--KREGFEPCDYAFSGAIKSCAVLGAYCNGQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDS--VSWNALIAALGQHGHGAEAVDVYEEMLKKGIRPDRITLLTVLTACSHAGLVDQGRKYFDSMETVYRIPPGADHYARLIDLLCRSGKFSDAESVIESLPFKPTAEIWEALLSGCRVHGNMELGIIAADKLFGLIPEHDGTYMLLSNMHAATGQWEEVARVRKLMRDRGVKKEVACSWIEMETQVHTFLVDDTSHPEAEAVYIYLQD-LGKEMRRLGYVPDTSFVLHDVESDGHKEDMLTTHSEKIAVAFGLMKLPPGTTIRIFKNLRTCGDCHNFFRFLSWVVQRDIILRDRKRFHHFRNGECSCGNFW 790          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPS---------------------------------TLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCV--HGLSLKVGLESDMYVGTSLINMYVKCCD----MSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLF-GKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEP--------------------GVEHYA---------------CVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH-HNLEIAEI 1329
            L+L + VH  +   GF+P A++  +++ +Y  S +L+ A  +F  ++ P                                  T++YN++I  ++ +      + ++ +M   G K DNFT+  VL   A L      +CV  H  +LK G      V  +L+++Y KC      +  AR++FD++  +D  SW  ++ GY+K+G   L E+L  G      +V++ AMISGY   G  ++AL +   M+   S ++ +  T  SV+ ACA +  L+ G+++H +  R   + +     +L+++Y KCG   +AR  FE++     +LV+WN +++ Y S G   EA   F++M     + + +++  ++SG + +G  + GLK F  MKR    EP                    G +++A                ++ +  + G + EA+ +   MP     S W A+++A  +H H  E  ++
Sbjct:   30 LQLARAVHGNIITFGFQPRAHILNRLIDVYCKSSELNYARQLFDEISEPDKIARTTMVSGYCASGDITLARGVFEKAPVCMRDTVMYNAMITGFSHNNDGYSAINLFCKMKHEGFKPDNFTFASVLAGLA-LVADDEKQCVQFHAAALKSGAGYITSVSNALVSVYSKCASSPSLLHSARKVFDEILEKDERSWTTMMTGYVKNGYFDLGEELLEGMDDNMKLVAYNAMISGYVNRGFYQEALEMVRRMV--SSGIELDEFTYPSVIRACATAGLLQLGKQVHAYVLR-REDFSFHFDNSLVSLYYKCGKFDEARAIFEKM--PAKDLVSWNALLSGYVSSGHIGEAKLIFKEM----KEKNILSWMIMISGLAENGFGEEGLKLFSCMKR-EGFEPCDYAFSGAIKSCAVLGAYCNGQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDSVS-WNALIAALGQHGHGAEAVDV 505          

Query:  358 YPFVLKCCAELSR--IWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMP--GRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERG-RKIHNFASRIGLESNVSIQTALLAMYAKCGS----LLDARQCFERVRXTQN------------------------------NLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQG 1458
            Y   L+ C  L R  + + + VHG  +  G +   ++   LI++Y K  +++ AR+LFD+++  D  +   +++GY   G+I LA  +F K P   R+ V + AMI+G++ N     A+ LF +M  K    KP+  T  SVL   A  A  E+   + H  A + G     S+  AL+++Y+KC S    L  AR+ F+ +                                    LVA+N MI+ Y + G   EA+     M+ +G++ D  T+  ++  C+ +GL+ +G +   Y+ R        ++   +V L  + G+  EA+ +  KMP +   S W A+LS      ++  A++  +    ++ +N  +++++ +  AE G  +E   L   +K +G
Sbjct:   15 YAANLRLCLPLRRTSLQLARAVHGNIITFGFQPRAHILNRLIDVYCKSSELNYARQLFDEISEPDKIARTTMVSGYCASGDITLARGVFEKAPVCMRDTVMYNAMITGFSHNNDGYSAINLFCKM--KHEGFKPDNFTFASVLAGLALVADDEKQCVQFHAAALKSGAGYITSVSNALVSVYSKCASSPSLLHSARKVFDEILEKDERSWTTMMTGYVKNGYFDLGEELLEGMDDNMKLVAYNAMISGYVNRGFYQEALEMVRRMVSSGIELDEFTYPSVIRACATAGLLQLGKQVHAYVLRREDFSFHFDN--SLVSLYYKCGKFDEARAIFEKMPAKDLVS-WNALLSGYVSSGHIGEAKLIFKE---MKEKNILSWMIMISGLAENGFGEEGLKLFSCMKREG 412          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTL-------------------------------HGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI-GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHG 999
            Y  + ++     LL+LG+QVHA + LR  +   +    +V++Y      D A AIF ++     + +N+++  Y                                 +GF EE ++++  M   G +  ++ +   +K CA L     G+  H   LK+G +S +  G +LI MY KC  + +AR++F  M   D  SWNALIA                                  Q+G   +A+ +++EMLKK   ++P+ +T+++VL AC+H+  +++GRK  +    +  +         L+ +  + G   DA    E +       + W  +++    HG
Sbjct:  289 YPSVIRACATAGLLQLGKQVHAYV-LRREDFSFHFDNSLVSLYYKCGKFDEARAIFEKMPAKDLVSWNALLSGYVSSGHIGEAKLIFKEMKEKNILSWMIMISGLAENGFGEEGLKLFSCMKREGFEPCDYAFSGAIKSCAVLGAYCNGQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDSVSWNALIA-------------------------------ALGQHGHGAEAVDVYEEMLKKG--IRPDRITLLTVLTACSHAGLVDQGRKYFDSMETVYRIPPGADHYARLIDLLCRSGKFSDAESVIESLPFKPTAEI-WEALLSGCRVHG 600          

Query:  103 GQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHG---LSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSS-WNALIAGYMKDGE----ICLAEDLFGKMP 630
            GQQ HAQ+   GF+     G  ++ MYA    ++ A  +F  +    ++ +N++I A   HG   E +++Y  M   G++ D  T   VL  C+    +  G+          ++   +D Y    LI++  +    SDA  + + +  +  +  W AL++G    G     I  A+ LFG +P
Sbjct:  436 GQQYHAQLLKIGFDSSLSAGNALITMYAKCGVVEEARQVFRTMPCLDSVSWNALIAALGQHGHGAEAVDVYEEMLKKGIRPDRITLLTVLTACSHAGLVDQGRKYFDSMETVYRIPPGADHY--ARLIDLLCRSGKFSDAESVIESLPFKPTAEIWEALLSGCRVHGNMELGIIAADKLFGLIP 617          

Query:   49 SFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVG---------------------------------TSLINMYVKCCDMSDARRLFDKMTVRDVS-SWNALIAG--------------------------------------YMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            SFYA +  S T K  LK   Q+HA++ + G +   +L  K++   +S  D+  A  +F  +  P    +N+IIR Y+ +   ++ + +Y  M    +  D+FT+P +LK C+ LS + +G+ VH    ++G ++D++V                                  T++++ Y +  +  +A  +F +M   DV   W AL++                                       Y K G++  A+ LF KM   N++ W AMISGY +NG A +A+ +F EM+ KD  V+P+ ++I S + ACA   +LE+ R ++ +  R     +V I +AL+ M+AKCGS+  AR  F+R      ++V W+ MI  Y  HGR  EA+S +  M   GV P+++TF GLL  C+HSG+V  G  +F+ M   + + P  +HYACV+DLLGRAG L +A ++I  MP+Q G ++WGA+LSAC+KH ++E+ E AA+ LF ++P N+G+YV LSN+YA A +W  V  +RV +K +G+ K+ GCSW EV G+   F  GD SHP+ +EI E  ++ +  ++K  G+V +    LHD+++EE E +L +HSE++AIA+GL++T  G  LR+TKNLR C +CH ATKLIS++ +REI+VRD NRFHHFKDG CSCGDYW
Sbjct:   22 SFYASLIDSATHKAQLK---QIHARLLVLGLQFSGFLITKLIHASSSFGDITFARQVFDDLPRPQIFPWNAIIRGYSRNNHFQDALLMYSNMQLARVSPDSFTFPHLLKACSGLSHLQMGRFVHAQVFRLGFDADVFVQNGLIALYAKCRRLGSARTVFEGLPLPERTIVSWTAIVSAYAQNGEPMEALEIFSQMRKMDVKPDWVALVSVLNAFTCLQDLKQGRSIHASVVKMGLEIEPDLLISLNTMYAKCGQVATAKILFDKMKSPNLILWNAMISGYAKNGYAREAIDMFHEMINKD--VRPDTISITSAISACAQVGSLEQARSMYEYVGRSDYRDDVFISSALIDMFAKCGSVEGARLVFDRT--LDRDVVVWSAMIVGYGLHGRAREAISLYRAMERGGVHPNDVTFLGLLMACNHSGMVREGWWFFNRMAD-HKINPQQQHYACVIDLLGRAGHLDQAYEVIKCMPVQPGVTVWGALLSACKKHRHVELGEYAAQQLFSIDPSNTGHYVQLSNLYAAARLWDRVAEVRVRMKEKGLNKDVGCSWVEVRGRLEAFRVGDKSHPRYEEI-ERQVEWIESRLKEGGFVANKDASLHDLNDEEAEETLCSHSERIAIAYGLISTPQGTPLRITKNLRACVNCHAATKLISKLVDREIVVRDTNRFHHFKDGVCSCGDYW 694          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSD----DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEI---YGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDK---------MTVR-----DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +F  +     ++   Q+HA     G   D    A+++   A+SD    DLD A  IF+++   +   +N+IIR ++     +  + I   Y  M    ++ + FT+P VLK CA+  +I  GK +HGL+LK G   D +V ++L+ MYV C  M DAR LF K         MT R     ++  WN +I GYM+ G+   A  LF KM  R++VSW  MISGY+ NG  + A+ +F EM K D  ++PN+VT++SVLPA +   +LE G  +H +A   G+  +  + +AL+ MY+KCG +  A   FER+   + N++ W+ MI  +A HG+  +A+  F  M  AGV+P ++ +  LL+ CSH GLV+ G +YF  M  V  +EP +EHY C+VDLLGR+G L EA++ I  MP++    IW A+L ACR   N+E+ +  A  L  + P +SG YV LSN+YA  G W EV  +R+ +K + ++K+PGCS  +++G  H F+  D SHP+AKEI   L+ E+  K++ AGY P T+ VL ++ EE+KE+ L  HSEK+A AFGL++TSPG  +R+ KNLRIC DCH++ KLIS++Y+R+I VRD  RFHHF+DG+CSC DYW
Sbjct:   26 LFPQINNCRTIRDLSQIHAVFIKSGQMRDTLAAAEILRFCATSDLHHRDLDYAHKIFNQMPQRNCFSWNTIIRGFSESDEDKALIAITLFYEMMSDEFVEPNRFTFPSVLKACAKTGKIQEGKQIHGLALKYGFGGDEFVMSNLVRMYVMCGFMKDARVLFYKNIIEKDMVVMTDRRKRDGEIVLWNVMIDGYMRLGDCKAARMLFDKMRQRSVVSWNTMISGYSLNGFFKDAVEVFREMKKGD--IRPNYVTLVSVLPAISRLGSLELGEWLHLYAEDSGIRIDDVLGSALIDMYSKCGIIEKAIHVFERL--PRENVITWSAMINGFAIHGQAGDAIDCFCKMRQAGVRPSDVAYINLLTACSHGGLVEEGRRYFSQMVSVDGLEPRIEHYGCMVDLLGRSGLLDEAEEFILNMPIKPDDVIWKALLGACRMQGNVEMGKRVANILMDMVPHDSGAYVALSNMYASQGNWSEVSEMRLRMKEKDIRKDPGCSLIDIDGVLHEFVVEDDSHPKAKEINSMLV-EISDKLRLAGYRPITTQVLLNLEEEDKENVLHYHSEKIATAFGLISTSPGKPIRIVKNLRICEDCHSSIKLISKVYKRKITVRDRKRFHHFQDGSCSCMDYW 646          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEE-KEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            L LGQ +H          D ++   ++  Y S  DLDSA  +F  +     + +NS+I  +   G  ++ +E++ +M    +K  + T   VL  CA++  +  G+ V     +  +  ++ +  ++++MY KC  + DA+RLFD M  +D  +W  ++ GY    +   A ++   MP ++IV+W A+IS Y QNG   +AL +F E L+    +K N +T++S L ACA   ALE GR IH++  + G+  N  + +AL+ MY+KCG L  +R+ F  V   + ++  W+ MI   A HG G+EAV  F  M  A V+P+ +TFT +   CSH+GLVD     F  M+  Y + P  +HYAC+VD+LGR+G L +A   I  MP+    S+WGA+L AC+ H NL +AE+A   L  LEP N G +V+LSNIYA+ G W+ V  LR  ++  G+KK PGCS  E++G  H FL GD +HP ++++Y   L E+ +K+K+ GY P+ S VL  + EEE KE SL  HSEKLAI +GL++T    V+RV KNLR+CGDCH+  KLIS++Y+REIIVRD  RFHHF++G CSC D+W
Sbjct:  147 LSLGQSLHGMAVKSAVGSDVFVANSLIHCYFSCGDLDSACKVFTTIKEKDVVSWNSMINGFVQKGSPDKALELFKKMESEDVKASHVTMVGVLSACAKIRNLEFGRQVCSYIEENRVNVNLTLANAMLDMYTKCGSIEDAKRLFDAMEEKDNVTWTTMLDGYAISEDYEAAREVLNSMPQKDIVAWNALISAYEQNGKPNEALIVFHE-LQLQKNMKLNQITLVSTLSACAQVGALELGRWIHSYIKKHGIRMNFHVTSALIHMYSKCGDLEKSREVFNSVE--KRDVFVWSAMIGGLAMHGCGNEAVDMFYKMQEANVKPNGVTFTNVFCACSHTGLVDEAESLFHQMESNYGIVPEEKHYACIVDVLGRSGYLEKAVKFIEAMPIPPSTSVWGALLGACKIHANLNLAEMACTRLLELEPRNDGAHVLLSNIYAKLGKWENVSELRKHMRVTGLKKEPGCSSIEIDGMIHEFLSGDNAHPMSEKVYG-KLHEVMEKLKSNGYEPEISQVLQIIEEEEMKEQSLNLHSEKLAICYGLISTEAPKVIRVIKNLRVCGDCHSVAKLISQLYDREIIVRDRYRFHHFRNGQCSCNDFW 738          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSD--DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKX---DNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQN-----------------------------NLVAWNTMITAYASHGRGSEAVSTFEDM-IVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            +Q H  M   G   D Y  +K+ AM A S    L+ A  +F  +  P++  +N++IRAY      +  + I+  +  +       + +T+PF++K  AE+S + +G+ +HG+++K  + SD++V  SLI+ Y  C D+  A ++F  +  +DV SWN++I G++                               Q G  ++AL LF +M  +D  VK + VT++ VL ACA    LE GR++ ++     +  N+++  A+L MY KCGS+ DA++ F+ +    N                             ++VAWN +I+AY  +G+ +EA+  F ++ +   ++ + IT    LS C+  G +++G     Y+K+ + +       + ++ +  + G L +++++   +  +    +W AM+     H
Sbjct:   47 KQTHGHMIRTGTFSDPYSASKLFAMAALSSFASLEYARKVFDEIPKPNSFAWNTLIRAYA--SGPDPVLSIWAFLDMVSESQCYPNKYTFPFLIKAAAEVSSLSLGQSLHGMAVKSAVGSDVFVANSLIHCYFSCGDLDSACKVFTTIKEKDVVSWNSMINGFV-------------------------------QKGSPDKALELFKKMESED--VKASHVTMVGVLSACAKIRNLEFGRQVCSYIEENRVNVNLTLANAMLDMYTKCGSIEDAKRLFDAMEEKDNVTWTTMLDGYAISEDYEAAREVLNSMPQKDIVAWNALISAYEQNGKPNEALIVFHELQLQKNMKLNQITLVSTLSACAQVGALELGRWIHSYIKK-HGIRMNFHVTSALIHMYSKCGDLEKSREVFNSVE-KRDVFVWSAMIGGLAMH 444          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYA------------------------SSDD------------LDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +  + +S T    L+ G+ VH  +   G + D Y G  ++ MYA                        S D+            +DS   +F  +     + YN+II  Y   G  E+ + +   M    LK D+FT   VL   +E   +  GK +HG  ++ G++SD+Y+G+SL++MY K   + D+ R+F ++              Y +DG                 +SW ++++GY QNG   +AL LF +M+   +KVKP  V   SV+PACAH A L  G+++H +  R G  SN+ I +AL+ MY+KCG++  AR+ F+R+       V+W  +I  +A HG G EAVS FE+M   GV+P+ + F  +L+ CSH GLVD    YF+ M +VY +   +EHYA V DLLGRAG+L EA + I KM ++   S+W  +LS+C  H NLE+AE  A  +F ++ EN G YV++ N+YA  G WKE+  LR+ ++ +G++K P CSW E+  K H F+ GD SHP   +I EF L  + ++++  GYV DTS VLHDV EE K   L  HSE+LA+AFG++NT PG  +RVTKN+RIC DCH A K IS+I EREIIVRD +RFHHF  GNCSCGDYW
Sbjct:  108 FPSVLKSCTMMMDLRFGESVHGFIVRLGMDCDLYTGNALMNMYAKLLGMGSKISVGNVFDEMPQRTSNSGDEDVKAETCIMPFGIDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTDLKPDSFTLSSVLPIFSEYVDVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRL--------------YCRDG-----------------ISWNSLVAGYVQNGRYNEALRLFRQMVT--AKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDE--VSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTKVYGLNQELEHYAAVADLLGRAGKLEEAYNFISKMCVEPTGSVWSTLLSSCSVHKNLELAEKVAEKIFTVDSENMGAYVLMCNMYASNGRWKEMAKLRLRMRKKGLRKKPACSWIEMKNKTHGFVSGDRSHPSMDKINEF-LKAVMEQMEKEGYVADTSGVLHDVDEEHKRELLFGHSERLAVAFGIINTEPGTTIRVTKNIRICTDCHVAIKFISKITEREIIVRDNSRFHHFNRGNCSCGDYW 715          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMS---DARRLFDKMTVRDVSSWNALIAGYMKDGEICL-------AEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKM 1248
            +Q+HAQ  +R         + ++++Y +   L  A+ +F  + +P  L + S+IR +T      + +  +  M   G   D+  +P VLK C  +  +  G+ VHG  +++G++ D+Y G +L+NMY K   M        +FD+M  R  +S +  +       E C+          +F  MP +++VS+  +I+GY Q+G+ E AL +  EM   D  +KP+  T+ SVLP  +    + +G++IH +  R G++S+V I ++L+ MYAK   + D+ + F R+       ++WN+++  Y  +GR +EA+  F  M+ A V+P  + F+ ++  C+H   + +G +   Y+ R       +   + +VD+  + G +  A+ +  +M
Sbjct:   25 KQLHAQF-IRTQSLSHTSASIVISIYTNLKLLHEALLLFKTLKSPPVLAWKSVIRCFTDQSLFSKALASFVEMRASGRCPDHNVFPSVLKSCTMMMDLRFGESVHGFIVRLGMDCDLYTGNALMNMYAKLLGMGSKISVGNVFDEMPQRTSNSGDEDV-----KAETCIMPFGIDSVRRVFEVMPRKDVVSYNTIIAGYAQSGMYEDALRMVREMGTTD--LKPDSFTLSSVLPIFSEYVDVIKGKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDG--ISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLR-GGFGSNIFIASALVDMYSKCGNIKAARKIFDRM 404          

Query:   25 LAQDPRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERV-RXTQNNLVAWNTMITAYASHGRGSE 1011
            L  D   +S   PIF      +++K G+++H  +  +G + D Y+G+ +V MYA S  ++ +  +F R+     + +NS++  Y  +G   E + ++ +M    +K     +  V+  CA L+ + +GK +HG  L+ G  S++++ ++L++MY KC ++  AR++FD+M V D  SW A+I G+   G    A  LF +M  +    N V++ A+++  +  GL ++A   F+ M K    +        +V      +  LE   + +NF S++ +E   S+ + LL+  +   +L  A +  E++      N+ A+  M   YAS+GR  E
Sbjct:  238 LKPDSFTLSSVLPIFSEYV--DVIK-GKEIHGYVIRKGIDSDVYIGSSLVDMYAKSARIEDSERVFSRLYCRDGISWNSLVAGYVQNGRYNEALRLFRQMVTAKVKPGAVAFSSVIPACAHLATLHLGKQLHGYVLRGGFGSNIFIASALVDMYSKCGNIKAARKIFDRMNVLDEVSWTAIIMGHALHGHGHEAVSLFEEMKRQGVKPNQVAFVAVLTACSHVGLVDEAWGYFNSMTKVYG-LNQELEHYAAVADLLGRAGKLE---EAYNFISKMCVEPTGSVWSTLLSSCSVHKNLELAEKVAEKIFTVDSENMGAYVLMCNMYASNGRWKE 564          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMY---ASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHD-VSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +Q+HA+M   G   D+Y   K ++      SSD L  A  +F   + P T L+N +IR ++     E ++ +Y RM C     + +T+P +LK C+ LS       +H    K+G E+D+Y   SLIN Y    +   A  LFD++   D  SWN++I GY+K G++ +A  LF KM  +N +SWT MISGY Q  + ++AL LF EM  ++S V+P+ V++ + L ACA   ALE+G+ IH++ ++  +  +  +   L+ MYAKCG + +A + F+ ++  + ++ AW  +I+ YA HG G EA+S F +M   G++P+ ITFT +L+ CS++GLV+ G   F  M+R Y+++P +EHY C+VDLLGRAG L EAK  I +MP++    IWGA+L ACR H N+E+ E     L  ++P + G YV  +NI+A    W +    R L+K QGV K PGCS   + G  H FL GD SHP+ ++I +     + +K++  GYVP+   +L D V ++E+E  +  HSEKLAI +GL+ T PG ++R+ KNLR+C DCH  TKLIS+IY+R+I++RD  RFHHF+DG CSCGDYW
Sbjct:   31 KQIHARMLKTGLMQDSYAITKFLSFCISSTSSDFLPYAQIVFDGFDRPDTFLWNLMIRGFSCSDEPERSLLLYQRMLCSSAPHNAYTFPSLLKACSNLSAFEETTQIHAQITKLGYENDVYAVNSLINSYAVTGNFKLAHLLFDRIPEPDDVSWNSVIKGYVKAGKMDIALTLFRKMAEKNAISWTTMISGYVQADMNKEALQLFHEM--QNSDVEPDNVSLANALSACAQLGALEQGKWIHSYLNKTRIRMDSVLGCVLIDMYAKCGEMEEALEVFKNIK--KKSVQAWTALISGYAYHGHGREAISKFMEMQKMGIKPNVITFTAVLTACSYTGLVEEGKLIFYSMERDYNLKPTIEHYGCIVDLLGRAGLLDEAKRFIQEMPLKPNAVIWGALLKACRIHKNIELGEEIGEILIAIDPYHGGRYVHKANIHAMDKKWDKAAETRRLMKEQGVAKVPGCSTISLEGTTHEFLAGDRSHPEIEKI-QSKWRIMRRKLEENGYVPELEEMLLDLVDDDEREAIVHQHSEKLAITYGLIKTKPGTIIRIMKNLRVCKDCHKVTKLISKIYKRDIVMRDRTRFHHFRDGKCSCGDYW 620          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCV-HGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDL 615
            L+ G+ +H+ +       D+ LG  ++ MYA   +++ A+ +F  +   S   + ++I  Y  HG   E +  +  M  +G+K +  T+  VL  C+    +  GK + + +     L+  +     ++++  +   + +A+R   +M ++ +   W AL+        I L E++
Sbjct:  263 LEQGKWIHSYLNKTRIRMDSVLGCVLIDMYAKCGEMEEALEVFKNIKKKSVQAWTALISGYAYHGHGREAISKFMEMQKMGIKPNVITFTAVLTACSYTGLVEEGKLIFYSMERDYNLKPTIEHYGCIVDLLGRAGLLDEAKRFIQEMPLKPNAVIWGALLKACRIHKNIELGEEI 438          

Query:   91 LLKLGQQVHAQMALRG-FEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIY-GRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKV---------KPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPS-IWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +L+ G+++HA     G  + ++++G+ +V MY +   + S   +F  + +    L+N++I  Y+ +   +E + ++ G     GL  ++ T   V+  C         + +HG  +K GL+ D +V  +L++MY +                                G+I +A  +FGKM  R++V+W  MI+GY  +   E AL L  +M   + KV         KPN +T+M++LP+CA  +AL +G++IH +A +  L ++V++ +AL+ MYAKCG L  +R+ F+++   Q N++ WN +I AY  HG G EA+     M+V GV+P+ +TF  + + CSHSG+VD GL+ F  MK  Y VEP  +HYACVVDLLGRAGR+ EA  L+  MP     +  W ++L A R H+NLEI EIAA++L  LEP  + +YV+L+NIY+ AG+W +   +R  +K QGV+K PGCSW E   + H F+ GD+SHPQ++++  +L + L ++++  GYVPDTS VLH+V E+EKE  L  HSEKLAIAFG+LNTSPG ++RV KNLR+C DCH ATK IS+I +REII+RD+ RFH FK+G CSCGDYW
Sbjct:  317 MLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRL-------------------------------GKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQI--PQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSEKLSGYL-ETLWERMRKEGYVPDTSCVLHNVEEDEKEILLCGHSEKLAIAFGILNTSPGTIIRVAKNLRVCNDCHLATKFISKIVDREIILRDVRRFHRFKNGTCSCGDYW 890          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVG-LESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEA------VSTFEDMIVAG-----VQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHN 1311
            L +G+QVHA   LR  E ++++   +VAMY     L S+  +         + +N+++ +   +    E +E    M   G++ D FT   VL  C+ L  +  GK +H  +LK G L+ + +VG++L++MY  C  +   RR+FD M  R +  WNA+IA                               GY+QN   ++AL LF  M ++ + +  N  T+  V+PAC  S A  R   IH F  + GL+ +  +Q  L+ MY++ G +  A + F ++     +LV WNTMIT Y       +A      +   E  +  G     ++P++IT   +L  C+    +  G +   Y  +  ++   V   + +VD+  + G L  ++ +  ++P Q     W  ++ A   H N
Sbjct:  218 LMMGKQVHAY-GLRKGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIA-------------------------------GYSQNEHDKEALLLFIGM-EESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKME--DRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIK-NNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIP-QKNVITWNVIIMAYGMHGN 598          

Query:  262 IIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESD-MYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAH---SAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSA-CRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGM 1413
            ++R+        E +  Y  M  LG+K DN+ +P +LK  A+L  + +GK +H    K G   D + V  +L+N+Y KC D     ++                               F ++  RN VSW ++IS        E AL  F  ML  D  V+P+  T++SV+ AC++      L  G+++H +  R G E N  I   L+AMY K G L  ++           +LV WNT++++   + +  EA+    +M++ GV+PD  T + +L  CSH  ++  G +   Y  +  S++      + +VD+     ++   + +   M       +W AM++   +  H+ E     A  LFI   E++G   +L+N    AG+
Sbjct:   68 LLRSKVRSNLLREAVLTYVDMIVLGIKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKV-------------------------------FDRISERNQVSWNSLISSLCSFEKWEMALEAFRCML--DENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKG-ELNSFIINTLVAMYGKLGKLASSKVLLGSFGG--RDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGM-FDRKIGLWNAMIAGYSQNEHDKE-----ALLLFIGMEESAG---LLANSTTMAGV 411          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAK-MVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAEL---SRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIG-LESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDM-IVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDY-MKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKM 1248
            ++LG+Q+HA +   G+  D+   A  +V +Y    D  +   +F R++  + + +NS+I +       E  +E +  M    ++  +FT   V+  C+ L     + +GK VH   L+ G E + ++  +L+ MY K   ++ ++ L      RD+ +WN +++       +C  E L                          +AL    EM+ +   V+P+  TI SVLPAC+H   L  G+++H +A + G L+ N  + +AL+ MY  C  +L  R+ F+ +   +  L  WN MI  Y+ +    EA+  F  M   AG+  ++ T  G++  C  SG          + +KR    +  V++   ++D+  R G++  A  +  KM
Sbjct:  113 MELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKG-ELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLS------SLCQNEQLL-------------------------EALEYLREMVLEG--VEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGL--WNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQN--TLMDMYSRLGKIDIAMRIFGKM 466          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKM--TVRDVSSWNAL-----IAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISG-YTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFAS 834
            I  S    + L  G+++HA         D  +G+ +V MYA    L  +  +F ++   + + +N II AY +HG  +E +++   M   G+K +  T+  V   C+    +  G +  + +    G+E        ++++  +   + +A +L + M        +W++L     I   ++ GEI  A++L    P  N+ S   +++  Y+  GL ++A  +   M  K+  V+          P C+    +E G ++H F +
Sbjct:  523 ILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIA-AQNLIQLEP--NVASHYVLLANIYSSAGLWDKATEVRRNM--KEQGVRKE--------PGCSW---IEHGDEVHKFVA 772          

Query:   82 GKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGK-------MPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            G N LK  + VHA +   G + D+YL  K++    +  + + +  IFH+   P+  L+N++I    L+   +E++EIY  M   GL  D+FT+PF+LK CA L    +G  +HGL +K G ESD +V TSL+++Y KC  + +A ++FD +  ++V++W A+I+GY+  G+   A D+F +       M  ++IVSW++MI GY  NGL ++AL LF +ML +    +P+   ++ VL ACA   ALE G    N   R     N  + TAL+ MYAKCG +  A + F  +R  + ++V WN  I+  A  G    A   F  M  +G++PD  TF GLL  C+H+GLVD G +YF+ M+RV+++ P +EHY C+VDLLGRAG L EA  L+  MPM+A   +WGA+L  CR H + ++ E   + L  LEP NSGNYV+LSNIY+ +  W++   +R ++  +G+KK PG SW EV+G  H FL GDTSHP +++IY   L EL K +KA+GYVP T +VL D+ EEEKEH +  HSEKLAIAFGL++T+P   +RV KNLR+CGDCH A K ISR   REIIVRD NRFH F DG+CSC DYW
Sbjct:   19 GFNSLKHLKHVHAALLRLGLDEDSYLLNKVLRFSFNFGNTNYSHRIFHQTKEPNIFLFNTMIHGLVLNDSFQESIEIYHSMRKEGLSPDSFTFPFLLKACARLLDSKLGIKLHGLVVKAGCESDAFVNTSLVSLYGKCGFIDNAFKVFDDIPEKNVAAWTAIISGYIGVGKCREAIDMFRRACSVFDGMLEKDIVSWSSMIQGYASNGLPKEALDLFFKMLNEG--FRPDCYAMVGVLCACARLGALELGNWASNLMDRNEFLGNPVLGTALIDMYAKCGRMDSAWEVFRGMR--KKDIVVWNAAISGLAMSGHVKAAFGLFGQMEKSGIEPDGNTFVGLLCACTHAGLVDEGRQYFNSMERVFTLTPEIEHYGCMVDLLGRAGFLDEAHQLVKSMPMEANAIVWGALLGGCRLHRDTQLVEGVLKQLIALEPSNSGNYVLLSNIYSASHKWEDAAKIRSIMSERGIKKVPGYSWIEVDGVVHEFLVGDTSHPLSEKIYA-KLGELVKDLKASGYVPTTDYVLFDIEEEEKEHFIGCHSEKLAIAFGLISTAPNDKIRVVKNLRVCGDCHEAIKHISRFTGREIIVRDNNRFHCFNDGSCSCKDYW 619          

Query:  109 QVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            QVHA +          L  K+   Y+S   L+ ++A+F++  NP+   Y SII A+T+H      +  Y +M    +  + FT+  +LK C     I   K +HG ++K G ++++YV T L+++Y +  D+  AR LFD M  + + S  A+I  Y K G I  A  LF  +  R+ + W  MI GY Q+GL  + L LF +ML  ++KV+PN VT+++VL AC  + ALE GR +H++    G+  NV + T+L+ MY+KCGSL DAR  FER+  +  ++VAWN+M+  YA HG   +A+  F++M + G QP +ITF G+L+ CSH+GLV  G K+F  MK  Y +EP VEHY C+V+LLG AG L EA +L+  M +   P +WG +L ACR H N+ + E  A  L      NSG YV+LSNIYA AG W+ V  +R L+K  G +K PGCS  EVN K H FL GD  HP+++EIYE +L+E+   +K  GY P T  VLHD+ + +KE SL  HSEKLA+AFGL+ T PG  +++ KNLR+C DCH  TKLIS+I  R++++RD NRFHHF +G CSCGDYW
Sbjct:   51 QVHAFLYRHNLHDHPILNFKLQRSYSSLGHLNRSLALFNKTQNPNVFFYTSIIHAHTIHNLHHLALLFYVQMLSQNVFPNAFTFSSILKSCP----IEPAKLLHGQAIKFGFDAELYVRTCLVDVYARGGDVVSARTLFDAMPEKSLVSLTAMITCYAKYGMIDEARVLFDGLEERDAICWNVMIDGYAQHGLPNEGLLLFRQML--NAKVRPNEVTVLAVLSACGQTGALETGRWVHSYIENNGIGINVRVGTSLIDMYSKCGSLEDARLVFERI--SNKDVVAWNSMVVGYAMHGFSQDALRLFKEMCMIGYQPTDITFIGVLNACSHAGLVSEGWKFFYSMKDEYGIEPKVEHYGCMVNLLGHAGYLEEAYELVKNMEIDQDPVLWGTLLGACRLHGNIALGEQIAEYLVSQNLANSGTYVLLSNIYAAAGNWEGVARVRTLMKESGFEKEPGCSSIEVNNKVHEFLAGDLRHPKSREIYE-MLEEINGWLKTHGYTPQTDIVLHDLEDAQKERSLGVHSEKLALAFGLITTKPGTTIKIVKNLRVCADCHAVTKLISKITGRKVVMRDRNRFHHFVNGLCSCGDYW 631          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTV-RDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVS 648
            L+ G+ VH+ +   G   +  +G  ++ MY+    L+ A  +F R++N   + +NS++  Y +HGFS++ + ++  M  +G +  + T+  VL  C+    +  G K  + +  + G+E  +     ++N+      + +A  L   M + +D   W  L+      G I L E +   +  +N+ +
Sbjct:  275 LETGRWVHSYIENNGIGINVRVGTSLIDMYSKCGSLEDARLVFERISNKDVVAWNSMVVGYAMHGFSQDALRLFKEMCMIGYQPTDITFIGVLNACSHAGLVSEGWKFFYSMKDEYGIEPKVEHYGCMVNLLGHAGYLEEAYELVKNMEIDQDPVLWGTLLGACRLHGNIALGEQIAEYLVSQNLAN 461          

Query:    1 MRTLLKPLLAQDPRFVSFYAPIFQSLTGKNL-----LKLGQQVHAQMAL-RGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGE-------------------------------------ICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDY 1875
            M+T    L  Q P+    +  + + L  K L      K  +++H+++ + +   P+  LG K++  YA+  +      IF  + + + + +N +IR+Y  +G  ++ + ++  M   G   DN+TYP VLK C+    +W+G  +HG  +K+GL+ ++Y+G  L++MY KC  +  ARR+ D+M  RD+ SWN+++AGY ++G                                      +   +D+F K+  ++++SW  MI+ Y  N +  +A+ L+ +M  +   V+P+ V+I SVLPAC   +A   GR+IH +  R  L  N+ ++ AL+ MYAKCG L +AR  F+++     ++V+W +MI+AY   G+G +AV+ F+ M  +G  PD I F  +L+ CSH+GLVD G   F+ M   Y + PG+EHY C+VDLLGRAG++ EA  L  +MPM+    +WG++LSACR + N+ IA +AA  L+ L PE SG YV+LSNIYA+AG W++V+ +R ++ ++G+KK PG S  E+N   + FL GD SH Q+KEIY+  L  L  ++K  GY+P+T   LHDV EE+KE  L  HSEKLAI F +LNT PG  +R+TKN+R+CGDCH ATKLIS+I EREII+RD +RFHHF+DG CSCGDY
Sbjct:    9 MKTKPFSLTTQKPQLSPKFTALTEDLCNKILDVNPDAKTLKKLHSKILIDQNLHPNPSLGIKLMRAYAACGEPCYTRHIFDEITDKNVVFFNVMIRSYVNNGLYQDALLVFKTMANQGFYPDNYTYPCVLKACSVSGNLWVGLQIHGAVVKLGLDMNLYIGNGLVSMYGKCKWLDAARRVLDEMPGRDMVSWNSMVAGYAQNGRFNDALKLCREMEDLKLKPDAGTMGSLLPAVTNTSCDNVLYVKDMFVKLKEKSLISWNVMIAVYVNNAMPNEAVDLYLQM--QVHGVEPDAVSISSVLPACGDLSAAVLGRRIHEYVERKKLRPNLLLENALIDMYAKCGCLKEARAVFDQMMF--RDVVSWTSMISAYGMSGQGKDAVALFKKMRDSGFTPDWIAFVSVLAACSHAGLVDEGRYCFNLMAE-YGITPGIEHYNCMVDLLGRAGKIDEAYHLTRQMPMEPNERVWGSLLSACRVYSNMNIALLAADHLYQLAPEQSGYYVLLSNIYAKAGRWQDVETVRSIMNSKGIKKIPGNSNVEINDHVYTFLAGDQSHTQSKEIYK-ALGVLVGRMKELGYMPETDSALHDVEEEDKECHLAVHSEKLAIVFAILNTKPGSTIRITKNIRVCGDCHVATKLISKIAEREIIIRDTHRFHHFRDGVCSCGDY 670          

Query:   22 LLAQDPRFVSFYAPIF--QSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEE-EKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +L +  RF + Y   F  ++ T  + L  GQ +H  +    F  D ++   ++  Y+S  DLDSA  +F ++     + +NS+I  +   G  EE ++++ RM     + +  T   VL  CA+   +  G+       + G++ ++ +  ++++MYVKC  + DARRLFDKM  +D+ SW  +I GY K G+   A  +F  MP  +I +W A+IS Y QNG  ++AL +F E L+ +   KPN VT+ S L ACA   A++ G  IH +  + G++ N  I T+L+ MY+KCG L  A + F  V   + ++  W+ MI   A HG G  A+  F  M    V+P+ +TFT LL  CSHSGLVD G  +F+ M+ VY V PG +HYAC+VD+LGRAG L EA +LI KMP+    S+WGA+L ACR + N+E+AE+A   L   +  N G YV+LSNIYA+AG W  V  LR  +K  G++K PGCS  EVNG  H FL GD SHP + EIY   LDE+  +IK+ GYV D S +L  V EE  KEH+L  HSEKLAIA+GL+   P   +R+ KNLR+CGDCH+  KLIS++Y R+I++RD  RFHHF  GNCSC DYW
Sbjct:  121 MLHESQRFPNSYTFPFVIKAATEVSSLLAGQAIHGMVMKASFGSDLFISNSLIHFYSSLGDLDSAYLVFSKIVEKDIVSWNSMISGFVQGGSPEEALQLFKRMKMENARPNRVTMVGVLSACAKRIDLEFGRWACDYIERNGIDINLILSNAMLDMYVKCGSLEDARRLFDKMEEKDIVSWTTMIDGYAKVGDYDAARRVFDVMPREDITAWNALISSYQQNGKPKEALAIFRE-LQLNKNTKPNEVTLASTLAACAQLGAMDLGGWIHVYIKKQGIKLNFHITTSLIDMYSKCGHLEKALEVFYSVE--RRDVFVWSAMIAGLAMHGHGRAAIDLFSKMQETKVKPNAVTFTNLLCACSHSGLVDEGRLFFNQMRPVYGVVPGSKHYACMVDILGRAGCLEEAVELIEKMPIVPSASVWGALLGACRIYGNVELAEMACSRLLETDSNNHGAYVLLSNIYAKAGKWDCVSRLRQHMKVSGLEKEPGCSSIEVNGIIHEFLVGDNSHPLSTEIYS-KLDEIVARIKSTGYVSDESHLLQFVEEEYMKEHALNLHSEKLAIAYGLIRMEPSQPIRIVKNLRVCGDCHSVAKLISKLYNRDILLRDRYRFHHFSGGNCSCMDYW 738          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPST---LLYNSIIRAYTLHGFSEETMEIYGRMHCLG---LKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNI----VSWTAMISGYTQNGL---------------AEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESN-VSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +F++       +LG  +H  + L GFE + ++   +VAMY    +LD A  +F  +        + +NSI+  Y   G  +  + ++ RM  LG   ++ D  +   VL  CA +     GK VHG++++ G   D++VG +L++MY KC  + +A ++FD++  +DV SWNA++ GY + G    A  LF KM   NI    VSW+A+I+G+ Q GL               A  AL LF  + K+D  VKPN  TI   L ACA  AAL  GR+IH +  R   +S  + +   L+ MYAK G +  AR  F+ ++  Q N V+W +++T Y  HGRG EA+  F++M   G+QPD +T   +L  CSHSG++D G+++F+ M + + V PG EHYAC+VDLLGRAGRL EA +LI  M M+    +W A+LS CR H N+E+ E AA+ L  L  EN G+Y +LSNIYA A  WK+V  +R L+K  G++K PGCSW +       F   D +HPQ+K+IYE +L  L ++IK  GYVP+TSF LHDV +EEK   L  HSEKLA+A+G+L ++PG  +R+TKNLR+CGDCH A   IS I + EII+RD +RFHHFK G+CSC  YW
Sbjct:   16 VFKACGDLMCCRLGASIHGVVFLTGFESNVFVCNAIVAMYGRCGELDCARKLFDEMCERRVYDLVSWNSIVAVYVQRGDCKNALRLFDRMCKLGDIDMRPDVVSLVNVLPACASMGAWLHGKAVHGIAVRSGSFEDLFVGNALVDMYAKCGMVDEASKVFDRIKEKDVVSWNAMVNGYSQIGRFEDALGLFEKMREENIELNVVSWSAVIAGFAQRGLGCETLDVFREMQHGEANDALELFSWIFKQDGLVKPNCFTISCALIACARLAALRLGRQIHAYILRNHFDSAFLYVANCLIDMYAKSGDIDVARFVFDNLK--QKNFVSWTSLMTGYGMHGRGKEALEVFDEMRRVGLQPDGVTLLVVLYACSHSGMIDQGIEFFNSMSKEFGVIPGQEHYACMVDLLGRAGRLNEAMELIEGMQMEPSSIVWVALLSGCRIHANVELGEHAAKQLLELNSENDGSYTLLSNIYANARRWKDVARVRSLMKNSGIRKRPGCSWVQGKKGTTTFYVADKTHPQSKQIYE-ILRGLTQRIKVLGYVPETSFALHDVDDEEKVDLLFEHSEKLALAYGILISAPGAPIRITKNLRVCGDCHNAITYISMIIDHEIILRDSSRFHHFKKGSCSCSGYW 643          

Query:  331 LGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR---DVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLK-KDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGL 1107
            LG   DN+T+P V K C +L    +G  +HG+    G ES+++V  +++ MY +C ++  AR+LFD+M  R   D+ SWN+++A Y+                               Q G  + AL LFD M K  D  ++P+ V++++VLPACA   A   G+ +H  A R G   ++ +  AL+ MYAKCG + +A + F+R++  + ++V+WN M+  Y+  GR  +A+  FE M    ++ + ++++ +++G +  GL
Sbjct:    4 LGWTPDNYTFPLVFKACGDLMCCRLGASIHGVVFLTGFESNVFVCNAIVAMYGRCGELDCARKLFDEMCERRVYDLVSWNSIVAVYV-------------------------------QRGDCKNALRLFDRMCKLGDIDMRPDVVSLVNVLPACASMGAWLHGKAVHGIAVRSGSFEDLFVGNALVDMYAKCGMVDEASKVFDRIK--EKDVVSWNAMVNGYSQIGRFEDALGLFEKMREENIELNVVSWSAVIAGFAQRGL 233          

Query:  745 PNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCF-ERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAG---VQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLS 1290
            P+  T   V  AC        G  IH      G ESNV +  A++AMY +CG L  AR+ F E       +LV+WN+++  Y   G    A+  F+ M   G   ++PD ++   +L  C+  G    G        R  S E      A +VD+  + G + EA  +  ++  +   S W AM++
Sbjct:    8 PDNYTFPLVFKACGDLMCCRLGASIHGVVFLTGFESNVFVCNAIVAMYGRCGELDCARKLFDEMCERRVYDLVSWNSIVAVYVQRGDCKNALRLFDRMCKLGDIDMRPDVVSLVNVLPACASMGAWLHGKAVHGIAVRSGSFEDLFVGNA-LVDMYAKCGMVDEASKVFDRIKEKDVVS-WNAMVN 191          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGR-----------------------------------MHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR--NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            + ++    + L+ G+Q+H    + G   D+ + + ++ MY   D L  A  +F ++  P  +  +++I  +   G  +ET E++ +                                   MH  GLK D  +   VL    +L    +G  +H   +K GL  D +V ++LI+MY KC   S+   +F++M   DV + NAL+ G  ++G +  A ++F +  G   N+VSWT+MI+  +QNG   +AL LF EM  +   VKPN VTI  +LPAC + AAL  G+  H F+ R G+ ++V + +AL+ MYAKCG +L +R CF+ +     NLV+WN+++  YA HG+  EA++ FE M   G +PD+++FT +LS C+  GL + G  YFD M R + VE  +EHY+C+V LLGR+GRL EA  +I +MP +    +WGA+LS+CR H+ +++ EIAA+ +F LEP N GNY++LSNIYA   MW EVD +R +++++G+KKNPG SW E+  K H+ L GD+SHPQ  +I E  L +L  ++K +GYVP T FVL DV E++KE  L  HSEKLA+  GLLNT PG  L+V KNLRIC DCH   K IS   +REI VRD NRFH FK G CSCGDYW
Sbjct:   16 VIKTCAALSALQTGKQMHCFALVSGLGLDSVVLSSLLHMYVQFDHLKDARNVFDKLPQPGVVTSSALISRFARKGRVKETKELFYQTRDLGVELNLVSWNGMISGFNRSGSYLDAVLMFQNMHLEGLKPDGTSVSSVLPAVGDLDMPLMGIQIHCYVIKQGLGPDKFVVSALIDMYGKCACASEMSGVFNEMDEVDVGACNALVTGLSRNGLVDNALEVFKQFKGMDLNVVSWTSMIASCSQNGKDMEALELFREM--QIEGVKPNSVTIPCLLPACGNIAALLHGKAAHCFSLRNGIFNDVYVGSALIDMYAKCGRMLASRLCFDMM--PNRNLVSWNSLMAGYAMHGKTFEAINIFELMQRCGQKPDHVSFTCVLSACTQGGLTEEGWFYFDSMSRNHGVEARMEHYSCMVTLLGRSGRLEEAYAMIKQMPFEPDSCVWGALLSSCRVHNRVDLGEIAAKRVFELEPRNPGNYILLSNIYASKAMWVEVDMVRDMMRSRGLKKNPGYSWIEIKNKVHMLLAGDSSHPQMPQIIE-KLAKLTVEMKKSGYVPHTDFVLQDVEEQDKEQILCGHSEKLAVVLGLLNTKPGFPLQVIKNLRICRDCHAVIKFISDFEKREIFVRDTNRFHQFKGGVCSCGDYW 652          

Query:  334 GLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPG----RNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKC-------------------------------GSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            G+  D+   P V+K CA LS +  GK +H  +L  GL  D  V +SL++MYV+   + DAR +FDK+    V + +ALI+ + + G +   ++LF +        N+VSW  MISG+ ++G    A+ +F  M  +   +KP+  ++ SVLPA         G +IH +  + GL  +  + +AL+ MY KC                               G + +A + F++ +    N+V+W +MI + + +G+  EA+  F +M + GV+P+++T   LL  C +   +  G     +  R   +   V   + ++D+  + GR+  ++     MP +   S W ++++    H
Sbjct:    5 GIVPDSRVLPTVIKTCAALSALQTGKQMHCFALVSGLGLDSVVLSSLLHMYVQFDHLKDARNVFDKLPQPGVVTSSALISRFARKGRVKETKELFYQTRDLGVELNLVSWNGMISGFNRSGSYLDAVLMFQNMHLEG--LKPDGTSVSSVLPAVGDLDMPLMGIQIHCYVIKQGLGPDKFVVSALIDMYGKCACASEMSGVFNEMDEVDVGACNALVTGLSRNGLVDNALEVFKQFKGMDLNVVSWTSMIASCSQNGKDMEALELFREMQIEGVKPNSVTIPCLLPACGNIAALLHGKAAHCFSLR-NGIFNDVYVGSALIDMYAKCGRMLASRLCFDMMPNRNLVS-WNSLMAGYAMH 359          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIY---------GRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            L  G+Q H Q  + GFE D ++ + ++ MY+    L +A  +F  +   + + + S+I  Y  +  + E + ++         G    +G   D+     VL  C+ +S   + + VHG+++KVGL+  M V  +L++ Y KC                               GE+ L+  +F  M  +++VSW +MI+ Y QNGL+  A  +F  MLK     K N VT+ ++L ACAH  AL  G  +H+   ++G  +NV + T+++ MY KCG    AR  F+ ++  + N+ +W  MI  Y  HG   EA+  F  MI AGV+P+ ITF  +L+ CSH+G ++ G ++F+ M   Y+VEPGVEHY C+VDLLGRAG + EA +LI  M ++    +WG++L+ACR H ++E+AEI+AR LF L+P N G YV+L+NIYA+AG WK+V+ +R+L+K +G+ K PG S  E+ G+ H+FL GD  HPQ ++IY++ L+EL  K++ AGYVP+ + VLHDV EEEKE  +  HSEKLA+AFG++N+ PG  + V KNLR+CGDCHT  KLIS+I  REIIVRD  RFHHFKDG CSCGDYW
Sbjct:   98 LNSGKQAHQQALVFGFESDLFVSSALIDMYSKCGKLSNARVLFDEIPRRNIVTWTSLITGYVQNDDAHEALMVFKEFLFEKSEGNGEEVGTSVDSVAMISVLSACSRVSNKAVSEGVHGVAIKVGLDKVMGVENTLLDAYAKC-------------------------------GEVSLSRKVFDDMAEKDVVSWNSMIAVYAQNGLSTDAFEVFHGMLKAGGG-KYNEVTLSTLLLACAHEGALRVGMCLHDQVIKMGYVNNVIMATSIIDMYCKCGQAEMARNAFDGMK--EKNVRSWTAMIAGYGMHGFAREALDVFYQMIWAGVKPNYITFISVLAACSHAGFLEEGWRWFNAMSHEYNVEPGVEHYGCMVDLLGRAGYIKEAYNLIKSMKVRRDFVLWGSLLAACRIHKDVELAEISARELFKLDPSNCGYYVLLANIYADAGRWKDVERMRILVKDRGLVKPPGYSLVELKGRVHVFLVGDKEHPQHEKIYKY-LEELSVKLQEAGYVPNMASVLHDVDEEEKEMIVRVHSEKLAVAFGVMNSIPGSTIHVIKNLRVCGDCHTVIKLISKIVSREIIVRDAKRFHHFKDGLCSCGDYW 666          

Query:  613 LFGKMPGR-NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIV---------AGVQPDNITFTGLLSGCS 1095
            LF K   R ++ SW ++I+   + G + ++L  F  M K D  +KPN  T    + +C+    L  G++ H  A   G ES++ + +AL+ MY+KCG L +AR  F+ +   + N+V W ++IT Y  +    EA+  F++ +           G   D++    +LS CS
Sbjct:   37 LFNKYFDRTDVYSWNSLIAELARGGDSCESLRAFSWMRKLD--IKPNRSTFPCAIKSCSALFDLNSGKQAHQQALVFGFESDLFVSSALIDMYSKCGKLSNARVLFDEI--PRRNIVTWTSLITGYVQNDDAHEALMVFKEFLFEKSEGNGEEVGTSVDSVAMISVLSACS 203          

Query:   85 KNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSD-DLDS-AVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVG-LESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFA--SRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTE-VNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            KNL ++ +QVHA++ L G +   Y+ AK++      +  +D   ++IF++VN P+  LYN++IR Y +    +E+ E Y  M   G+   +FT+  + K C     + +G+ +HG ++ VG    D++VG S+I+MY+KC  +   R++FD+M  RDV SW  LI+ Y+K G +  A +LF  +P +++V+WT M+SG+ QN    +A+  F++M  ++  V+ + +T++ V+ ACA   A +    I + A  S  G + +V + +AL+ MY+KCGS+ DA + F+ ++  + N+ ++++MI  +A HGR  +A+  F++M+   ++P+ +TF G+L+ CSH+G+V+ G + F+ M++ Y ++P  +HY C+VDLLGRAGRL EA +L+  MP++    +WGA+L ACR H + +IA IAA  LF LEP   GNY++L+NIYA  G W +V  +R L++ +G++KNP  SW E   G  H F  GD +HP++ EI +  L++L  +++A GY P  S V +DV++E+K   L THSEKLA+AFGL++T PG  +R+ KNLRIC DCH+     S+I  REIIVRD+ RFHHF DG CSCG++W
Sbjct:   57 KNLTQI-KQVHARILLNGLDQSCYVLAKLIRTLTKLNIPVDPYPLSIFNQVNYPNPFLYNALIRGYLIEERLKESTEFYSLMRKEGVVPVSFTFTALFKACGAKMDVGLGRQIHGQTILVGGFGEDLHVGNSMIDMYIKCGFLECGRKVFDEMPNRDVISWTELISAYVKSGNMESAGELFDGLPVKDMVAWTVMVSGFAQNAKPREAIMFFEKM--QEFGVETDEITLIGVISACAQLGAAKYADWIRDVAEKSEFGGKHSVVVGSALIDMYSKCGSVGDAYRVFQGMK--ERNVYSYSSMILGFAMHGRVHDAMKLFDEMVKTEIKPNRVTFIGVLTACSHAGMVEQGWQIFELMEKCYGIKPSADHYTCMVDLLGRAGRLQEAHELVKTMPIEPHGGVWGALLGACRIHKSPDIAAIAANHLFELEPYCIGNYILLANIYASCGRWNDVSTVRKLMRTRGLRKNPAFSWIESEKGMVHEFFSGDMTHPRSGEIKQ-ALEDLLDRLEAKGYQPHLSSVSYDVNDEDKRRILMTHSEKLALAFGLISTIPGSKIRIVKNLRICEDCHSVICGASQITGREIIVRDIMRFHHFHDGICSCGNFW 654          

Query:   46 VSF-YAPIFQSLTGKNLLKLGQQVHAQMAL-RGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYG-------------------------------RMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLK--VGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASR-IGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASH 996
            VSF +  +F++   K  + LG+Q+H Q  L  GF  D ++G  M+ MY     L+    +F  + N   + +  +I AY   G  E   E++                                +M   G++ D  T   V+  CA+L        +  ++ K   G +  + VG++LI+MY KC  + DA R+F  M  R+V S++++I G+   G +                                 A+ LFDEM+K  +++KPN VT + VL AC+H+  +E+G +I     +  G++ +    T ++ +  + G L +A +  + +    +  V W  ++ A   H
Sbjct:  145 VSFTFTALFKACGAKMDVGLGRQIHGQTILVGGFGEDLHVGNSMIDMYIKCGFLECGRKVFDEMPNRDVISWTELISAYVKSGNMESAGELFDGLPVKDMVAWTVMVSGFAQNAKPREAIMFFEKMQEFGVETDEITLIGVISACAQLGAAKYADWIRDVAEKSEFGGKHSVVVGSALIDMYSKCGSVGDAYRVFQGMKERNVYSYSSMILGFAMHGRV-------------------------------HDAMKLFDEMVK--TEIKPNRVTFIGVLTACSHAGMVEQGWQIFELMEKCYGIKPSADHYTCMVDLLGRAGRLQEAHELVKTMPIEPHGGV-WGALLGACRIH 463          

Query:  169 MVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKV----GLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            ++  Y  ++DLD+A    +  +    + +N++I  Y   G   E  E++ +M    ++ D FT+  V+  CA      +GK +H   LK       +  M V  +LI  Y KC  +  A+ +F+KM  RD+ SWN +++GY+    +  A+  F +MP +NI+SW  MISG  Q G AE+AL  F+ M  K    +P        + +C+   +L+ GR++H    R G ES++S   AL+ MYA+CG ++DA  C   +     + ++WN MI A   HG+G++A+  FE+M+  G+ PD I+F  ++S CSH+GLV  G KYFD M  VY V P  EHYA ++DLL RAG+ +EAK+++  MP + G  IW A+L+ CR H N+++   AA  LF L+P++ G YV+LSN+YA AG W ++  +R L++ +GVKK PGCSW EV  K H FL GD +HP+ ++IY + L++L  +++  GYVPDT +VLHDV  + KEH L+THSEKLA+A+G +    G  +RV KNLRICGDCH A K +S++  REI+VRD  RFHHF+DG CSCGDYW
Sbjct:  121 IITGYVKNNDLDAAKEFLNGTSKKLGVAWNAMISGYAHRGLYLEAFEMFRKMIMSKIQLDEFTFTSVISVCANAGCFRLGKEMHAYFLKTVANPAPDVAMPVNNALITFYWKCGKVDIAQEIFNKMPERDLVSWNIILSGYVNVRCMDEAKSFFNEMPEKNILSWIIMISGLAQIGFAEEALKFFNRM--KLQGFEPCDYAFAGAIISCSVLGSLKHGRQLHAQVVRYGYESSLSAGNALITMYARCG-VVDAAHCLF-INMPCVDAISWNAMIAALGQHGQGTQAIELFEEMLKEGILPDRISFLTVISACSHAGLVKEGRKYFDSMHNVYGVNPDEEHYARIIDLLCRAGKFSEAKEVMESMPFEPGAPIWEALLAGCRIHGNIDLGIEAAERLFELKPQHDGTYVLLSNMYAVAGQWNDMAKVRKLMRDRGVKKEPGCSWIEVENKVHSFLVGDANHPEVRQIYNY-LEQLVLEMRKIGYVPDTKYVLHDVESDLKEHELSTHSEKLAVAYGFMKLPHGATVRVFKNLRICGDCHNAFKFMSKVVGREIVVRDGKRFHHFRDGKCSCGDYW 689          

Query:  244 TLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELS-RIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCD---------MSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNF----ASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERV-----------------------------RXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            ++ YN++I AY+ +      +E++  M     + DN+T+  VL   A ++ +    + +H   +K G      V  +LI+ YVKC           M++AR+LFD+M  RD  SW  +I GY+K+ ++  A++       +  V+W AMISGY   GL  +A  +F +M+   SK++ +  T  SV+  CA++     G+++H +     +    +  + +  AL+  Y KCG +  A++ F ++                                + N+++W  MI+  A  G   EA+  F  M + G +P +  F G +  CS  G +  G +    + R Y  E  +     ++ +  R G +  A  L   MP     S W AM++A  +H
Sbjct:    4 SVFYNAMITAYSHNHDGHAAIELFCDMQRDNFRPDNYTFTSVLGALALVAEKEKHCQQLHCAVVKSGTGFVTSVLNALISSYVKCAASPSAQSSSLMAEARKLFDEMPNRDELSWTTIITGYVKNNDLDAAKEFLNGTSKKLGVAWNAMISGYAHRGLYLEAFEMFRKMIM--SKIQLDEFTFTSVISVCANAGCFRLGKEMHAYFLKTVANPAPDVAMPVNNALITFYWKCGKVDIAQEIFNKMPERDLVSWNIILSGYVNVRCMDEAKSFFNEMPEKNILSWIIMISGLAQIGFAEEALKFFNRMKLQGFEPCDYAFAGAIISCSVLGSLKHGRQLHAQVVR-YGYESSLSAGNALITMYARCGVVDAAHCLFINMPCVDAIS-WNAMIAALGQH 396          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIG-KCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICL----AEDLFGKMPGRN----IVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMS-VLPACAHSAALERGRKIHNFASRIGLE 849
            LK G+Q+HAQ+   G+E     G  ++ MYA    +D+A  +F  +     + +N++I A   HG   + +E++  M   G+  D  ++  V+  C+    +  G K    +    G+  D      +I++  +    S+A+ + + M        W AL+AG    G I L    AE LF   P  +    ++S    ++G   N +A+    + D  +KK+     +W+ + + V       A     R+I+N+  ++ LE
Sbjct:  333 LKHGRQLHAQVVRYGYESSLSAGNALITMYARCGVVDAAHCLFINMPCVDAISWNAMIAALGQHGQGTQAIELFEEMLKEGILPDRISFLTVISACSHAGLVKEGRKYFDSMHNVYGVNPDEEHYARIIDLLCRAGKFSEAKEVMESMPFEPGAPIWEALLAGCRIHGNIDLGIEAAERLFELKPQHDGTYVLLSNMYAVAG-QWNDMAKVRKLMRDRGVKKEPGC--SWIEVENKVHSFLVGDANHPEVRQIYNYLEQLVLE 592          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGR-MHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRD--VSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            LK+ + V  +M LR           M++++ +   +D A+A F  ++    + +NS+I     HGF  E ++ +   +    LK D F+    L  CA L ++  GK +HG  ++   ++   VG +LI+MY K   +  ARR+ ++  + D  V ++ AL+ GY+K G+I  A  +F  +   ++V+WTAMI GY QNGL   A+ +F  M+ +  +  PN  T+ ++L A +   +L  G++IH  A R G   + S+  AL  MYAK GS+  AR+ F  +R  ++  V+W +MI A A HG G EA+  FE M+  G++PD+IT+ G+LS C+H GLV+ G  YFD MK V+ ++P + HYAC+VDL GRAG L EA   +  MPM+     WG++LS+C+ + N+++A++AA  L ++EP NSG Y  L+N+Y+  G W +   +R L+KA+GVKK  G SW ++  K H+F   D  HPQ  EIY+ ++D++ K+IK  G+ PDT  VLHD+  E K+  L  HSEKLAIAFG+++T     LR+ KNLR+C DCH A K IS++ +REIIVRD  RFHHFKDG+CSC DYW
Sbjct:  196 LKMAKVVFDRMKLRNTSS----WNAMISLHMNCGRVDLALAQFELLSERDIVSWNSMIAGCNQHGFDNEALQFFSSILKDTSLKPDRFSLASALSACANLEKLSFGKQIHGYIVRTMFDASGAVGNALISMYAKSGGVEIARRIIEQSGISDLDVIAFTALLNGYVKLGDITPARQIFNSLKDPDVVAWTAMIVGYVQNGLNNDAIEVFKTMVSEGPR--PNSFTLAAMLSASSSVTSLNHGKQIHASAIRSGEALSPSVGNALTTMYAKAGSINGARKVFNLLRQNRDT-VSWTSMIMALAQHGLGEEAIELFEQMLTLGIKPDHITYVGVLSACTHGGLVEQGRSYFDLMKNVHKIDPTLSHYACMVDLFGRAGLLQEAYKFVENMPMEPDVIAWGSLLSSCKVYKNVDLAKVAAERLLLIEPNNSGAYSALANVYSSCGKWDDAAKIRKLMKARGVKKEQGLSWVQIQNKTHVFGVEDGLHPQKDEIYK-MMDKIWKEIKKMGFAPDTESVLHDLEVEVKDQILRYHSEKLAIAFGIISTPENTTLRIMKNLRVCNDCHNAIKFISKLVDREIIVRDATRFHHFKDGSCSCKDYW 785          

Query:   73 SLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM---------------HCLGLKXD----------------NFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFER--------------------------VRXTQNNL-----VAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLK-YFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            SL  ++ LK G+ +HAQM   G     YL   ++ +YA +     A  +F+ +   +T  +N+I+  Y   G  E+  +++  +               + +G   D                 FT   VL  CA      IGK VH   +K+GL + + V  SL+NMY K  D+  A+ +FD+M +R+ SSWNA+I+ +M  G + LA   F  +  R+IVSW +MI+G  Q+G   +AL  F  +L KD+ +KP+  ++ S L ACA+   L  G++IH +  R   +++ ++  AL++MYAK G +  AR+  E+                           R   N+L     VAW  MI  Y  +G  ++A+  F+ M+  G +P++ T   +LS  S    ++ G + +   ++   ++ P V +   +  +  +AG +  A+ +   +        W +M+ A  +H
Sbjct:   23 SLKSRDPLK-GKSIHAQMVKLGLTFSVYLMNNLMNLYAKTGFHLDAHDLFNEMPVKTTFSWNTILSGYAKQGKLEKAHQVFDLIPVRDSVSWTTIIVGYNQMGRFEDAIKIFVDMVKDKVLPTQFTLTNVLASCAATGSRGIGKKVHSFVVKLGLHACVPVANSLLNMYAKTGDLKMAKVVFDRMKLRNTSSWNAMISLHMNCGRVDLALAQFELLSERDIVSWNSMIAGCNQHGFDNEALQFFSSIL-KDTSLKPDRFSLASALSACANLEKLSFGKQIHGYIVRTMFDASGAVGNALISMYAKSGGVEIARRIIEQSGISDLDVIAFTALLNGYVKLGDITPARQIFNSLKDPDVVAWTAMIVGYVQNGLNNDAIEVFKTMVSEGPRPNSFTLAAMLSASSSVTSLNHGKQIHASAIRSGEALSPSVGN--ALTTMYAKAGSINGARKVFNLLRQNRDTVSWTSMIMALAQH 492          

Query:  406 GKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDL---IXKMPMQAGPSIWGAMLSACRKHHNLEIA 1323
            GK +H   +K+GL   +Y+  +L+N+Y K     DA  LF++M V+   SWN +++GY K G++  A  +F  +P R+ VSWT +I GY Q G  E A+ +F +M+K   KV P   T+ +VL +CA + +   G+K+H+F  ++GL + V +  +LL MYAK G L  A+  F+R++    N  +WN MI+ + + GR   A++ FE +     + D +++  +++GC+  G  +  L++F  + +  S++P     A  +       +L+  K +   I +    A  ++  A++S   K   +EIA
Sbjct:   32 GKSIHAQMVKLGLTFSVYLMNNLMNLYAKTGFHLDAHDLFNEMPVKTTFSWNTILSGYAKQGKLEKAHQVFDLIPVRDSVSWTTIIVGYNQMGRFEDAIKIFVDMVK--DKVLPTQFTLTNVLASCAATGSRGIGKKVHSFVVKLGLHACVPVANSLLNMYAKTGDLKMAKVVFDRMKL--RNTSSWNAMISLHMNCGRVDLALAQFELL----SERDIVSWNSMIAGCNQHGFDNEALQFFSSILKDTSLKPDRFSLASALSACANLEKLSFGKQIHGYIVRTMFDASGAVGNALISMYAKSGGVEIA 332          

Query:    4 RTLLKPLLAQDPRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            RTLLK LLAQDP  +SFYAPIFQSLT +NLLKLGQQVHAQMALRG EP+A+LGAKMVAMYASSD+LDSAV IFHRVNNPSTLLYNSIIRAYTL+G+SE+TMEIYG+MH LGLK DNFTYPFVLKCCA LS IW+GKCVH LSL++GL SDMYVGTSLI+MYVKC +MSDAR  FDKMTVRDVSSWNALIAGYMKDGEIC AEDLF +MP +NIVSWTAMISGYTQNGLAEQAL LFDEML+KDS+VKPNWVTIMSVLPACAHSAALERGR+IHNFASR GL+SN SIQTALLAMYAKCGSL DARQCFERV  T+N+LVAWNTMITAYASHGRGSEAVSTFEDMI AG+QPDNITFTGLLSGCSHSGLVD GLKYF+ MK +YS+EP VEHYACVVDLLGRAGRL EA DL+ KMPMQAGPSIWGA+LSACRKHHNLEIAEIAAR LFILEP+NSGNYV+LSNIYA+AGMWKEVD+LR LLK+QG+KKNPGCSW EVNGKAHLFLGGDT HPQAKEIYE LL+ELP KIKAAGYVPDTSFVLHDVSEEEKEH+LTTHSEKLAIAFGLLN SPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHF+DG CSCGDYW
Sbjct:    4 RTLLKSLLAQDPTCISFYAPIFQSLTSQNLLKLGQQVHAQMALRGLEPNAFLGAKMVAMYASSDNLDSAVNIFHRVNNPSTLLYNSIIRAYTLYGYSEKTMEIYGQMHRLGLKGDNFTYPFVLKCCANLSSIWLGKCVHSLSLRIGLASDMYVGTSLIDMYVKCGEMSDARSSFDKMTVRDVSSWNALIAGYMKDGEICFAEDLFRRMPCKNIVSWTAMISGYTQNGLAEQALVLFDEMLRKDSEVKPNWVTIMSVLPACAHSAALERGRQIHNFASRTGLDSNTSIQTALLAMYAKCGSLSDARQCFERVHQTENSLVAWNTMITAYASHGRGSEAVSTFEDMIGAGLQPDNITFTGLLSGCSHSGLVDGGLKYFNCMKTIYSIEPRVEHYACVVDLLGRAGRLVEAIDLVSKMPMQAGPSIWGALLSACRKHHNLEIAEIAARKLFILEPDNSGNYVLLSNIYADAGMWKEVDDLRALLKSQGMKKNPGCSWIEVNGKAHLFLGGDTCHPQAKEIYEVLLEELPNKIKAAGYVPDTSFVLHDVSEEEKEHNLTTHSEKLAIAFGLLNASPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFRDGCCSCGDYW 628          

Query:  106 QQVHAQMAL-RGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDG------EIC-------------------------------LAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +++H+ + + +    DA LG K++  YA+  +      +F R+   + + +N +IR+Y  +    + + +Y  M   G   DN+TYP VLK C+    +W+G  +HG  +KVGL+ ++++G  LI MY KC  + +AR + D+M  RDV S N+++AGY ++G      E+C                                 +++F K+  +++VSW  MI+ Y  N +  +A+ LF ++  + S ++P+ VTI SVLPAC   +AL  G++IH +  R  L  N+ ++ AL+ MYAKCG L DAR+ F+ ++    ++V+W +M++AY   G+G +AV+ F  M  +GV PD+I F  +++ CSH+GL++ G  YF+ M +   +EP +EH+AC+VDLLGRAGR+ EA   + +M ++    +WGA+LSACR + N+ +  +AA  LF L PE SG YV+LSNIYA+AG W++V  +R ++K++G+KK PG S  E+  + H FL GD SHP++KEIYE  LD L  K+K  GYVP+T   LHDV EEEKE  L  HSEKLAI F +LNT PG  +R+TKNLR+CGDCH A KLIS+I EREI++RD NRFHHFKDG CSCGDYW
Sbjct:   17 KELHSSIVVDQRLRSDASLGIKLMRAYAACGEPRITRHLFDRIPEKNVVFFNVMIRSYVNNHLYHDALLVYKTMSHNGFDPDNYTYPCVLKACSGSDNLWVGLQIHGAVVKVGLDMNLFIGNGLIAMYGKCRCLVEARSVLDQMPCRDVISCNSMVAGYAQNGRFNDALEVCREMEAFKLKPDAGTMASLFQAVTNTSADNVLYVKEMFMKLVKKSLVSWNVMIAVYVNNSMPGEAVDLFLQL--EVSGIEPDAVTIASVLPACGDLSALLLGKRIHEYVERKRLRPNLLLENALIDMYAKCGCLQDAREVFDAMKF--QDVVSWTSMMSAYGRCGQGHDAVALFRKMQDSGVSPDSIAFVSVMAACSHAGLLEEGQYYFNLMTKECRIEPRIEHFACMVDLLGRAGRVDEAYSFVKQMSLEPNERVWGALLSACRVYSNMNVGLLAADRLFQLAPEQSGYYVLLSNIYAKAGRWQDVTTVRSIMKSRGIKKIPGVSNVELKDQVHTFLAGDRSHPESKEIYE-ELDVLVGKMKELGYVPETDSALHDVEEEEKECHLAVHSEKLAIVFAILNTDPGTAIRITKNLRVCGDCHIAIKLISKIAEREIVIRDTNRFHHFKDGMCSCGDYW 640          

Query:   55 YAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELS--------------------------RIWIGKCVHG------LSLKV-GLESDMYVGTSLINMYVKCCDMSD---ARRLFD----KMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGR 1215
            Y  + ++ +G + L +G Q+H  +   G + + ++G  ++AMY     L  A ++  ++     +  NS++  Y  +G   + +E+   M    LK D  T   + +     S                           +++   + G      L L+V G+E D     ++ ++   C D+S     +R+ +    K    ++   NALI  Y K G +  A ++F  M  +++VSWT+M+S Y + G    A+ LF +M  +DS V P+ +  +SV+ AC+H+  LE G+   N                           L  ++C       +  +  +  M+      GR  EA S  + M    ++P+   +  LLS C     ++VGL   D + ++   + G  +Y  + ++  +AGR
Sbjct:  102 YPCVLKACSGSDNLWVGLQIHGAVVKVGLDMNLFIGNGLIAMYGKCRCLVEARSVLDQMPCRDVISCNSMVAGYAQNGRFNDALEVCREMEAFKLKPDAGTMASLFQAVTNTSADNVLYVKEMFMKLVKKSLVSWNVMIAVYVNNSMPGEAVDLFLQLEVSGIEPD---AVTIASVLPACGDLSALLLGKRIHEYVERKRLRPNLLLENALIDMYAKCGCLQDAREVFDAMKFQDVVSWTSMMSAYGRCGQGHDAVALFRKM--QDSGVSPDSIAFVSVMAACSHAGLLEEGQYYFN---------------------------LMTKEC-----RIEPRIEHFACMVDLLGRAGRVDEAYSFVKQM---SLEPNERVWGALLSACRVYSNMNVGLLAADRLFQLAPEQSG--YYVLLSNIYAKAGR 486          

Query:  142 EPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSL----KVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            E D      M+  Y  ++DL +A  +   ++    +++N++I  Y  H   +E + ++ +M  LG+  D FTY  V+  CA   +  +GK VH   L    K  ++  + V  +L+ +Y KC  + +AR +F+ M V+D+ SWNA+++GY+  G I  A+  F +MP R+I++WT MISG  QNGL E+A+ LF++M  +    +P        + +CA   ALE GR++H     +G +S++S   AL+ MYA+CG   DA   F  +    +  V+WN MI A A HG G +A+  FE M+ A + PD ITF  +LS CSH+GLV  G  YF  M+  Y + P   HYA ++DLL R G   EAK LI  MP + G  IW A+L+ CR H N+++   AA  LF L P++ G Y++LSN+YA  G W +V  +R L++ +GVKK PGCSW +V    H+FL GDT HP+ + +Y++ L++L  +++  GY+PDT FVLHD+  E KE+SL+THSEKLA+AFGL+    G  +RV KNLR CGDCHTA K +SR+  R+IIVRD  RFHHF++G CSCG+YW
Sbjct:  112 ERDELSWTTMITGYIRNEDLHAARELLDGMDERMEVVWNAMISGYAHHNSFQEALLLFRKMRLLGIHQDEFTYTSVISTCANNGQFQLGKQVHAYILRTEAKPTVDFSLSVNNTLLTLYYKCGKLDEARYIFNNMPVKDLVSWNAILSGYVSAGRIQEAKSFFKEMPERSILTWTVMISGLAQNGLGEEAMTLFNQM--RSEGFEPCDYAFSGAITSCAALGALEHGRQLHAQLISLGFDSSLSAANALITMYARCGVFKDANSVFLTMPCIDS--VSWNAMIAALAQHGHGVQAIDLFEQMLKADILPDRITFLIILSACSHAGLVKEGRHYFSSMRVCYGISPDEGHYARMIDLLCRCGEFTEAKGLIESMPFEPGGPIWEALLAGCRTHGNMDLGIQAAERLFELVPQHDGTYILLSNLYAAIGRWDDVAKVRKLMRDRGVKKEPGCSWIDVENMVHVFLVGDTEHPEVQAVYKY-LEQLGLEMRKLGYLPDTKFVLHDMESEHKEYSLSTHSEKLAVAFGLMKLPLGATIRVFKNLRSCGDCHTAIKFMSRVVGRDIIVRDAKRFHHFRNGECSCGNYW 689          

Query:  244 TLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKC--VHGLSLKVGLESDMYVGTSLINMYVKCCD---------MSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI----GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMK-------------------RVYSVEPGVEHYA---------------CVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH-HNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKE 1422
            T+ YN++I  Y+ +     ++ ++  M   G + ++FTY  VL   A++      +C  +H   +K G      V  +L+++YV+C           M +AR LF++M  RD  SW  +I GY+++ ++  A +L   M  R  V W AMISGY  +   ++AL LF +M  +   +  +  T  SV+  CA++   + G+++H +  R      ++ ++S+   LL +Y KCG L +AR  F  +     +LV+WN +++ Y S GR  EA S F++M    +    +T+T ++SG + +GL +  +  F+ M+                    + ++E G + +A                ++ +  R G   +A  +   MP     S W AM++A  +H H ++  ++  + L      +   ++++ +  + AG+ KE
Sbjct:    4 TVCYNAMITGYSRNNDGYASIRLFCEMRQGGFRPNDFTYTTVLSGVAQIVDAE-KQCQQLHCAVVKSGTGFATSVWNALLSVYVRCASSPLVSSSSLMGEARNLFNEMPERDELSWTTMITGYIRNEDLHAARELLDGMDERMEVVWNAMISGYAHHNSFQEALLLFRKM--RLLGIHQDEFTYTSVISTCANNGQFQLGKQVHAYILRTEAKPTVDFSLSVNNTLLTLYYKCGKLDEARYIFNNM--PVKDLVSWNAILSGYVSAGRIQEAKSFFKEMPERSI----LTWTVMISGLAQNGLGEEAMTLFNQMRSEGFEPCDYAFSGAITSCAALGALEHGRQLHAQLISLGFDSSLSAANALITMYARCGVFKDANSVFLTMPCIDSVS-WNAMIAALAQHGHGVQAIDLFEQMLKADILPDRITFLIILSACSHAGLVKE 436          

Query:  538 VRDVSSWNALIAGYMKDGEICLAEDLFGKMP----GRNIVSWTAMISGYTQNGLAE-QALFLFDEMLKKDSKVKPN-WVTIMSVLPACAHSAALERGR---KIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACV----VDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENS--GNYVMLSNIYAEAGMWKEVDNLRVLLKAQG 1458
            +RD   +NA+I GY ++ +   +  LF +M       N  ++T ++SG  Q   AE Q   L   ++K  +    + W  ++SV   CA S  +       +  N  + +     +S  T ++  Y +   L  AR+  + +   +   V WN MI+ YA H    EA+  F  M + G+  D  T+T ++S C+++G   +G +   Y+ R    +P V+    V    + L  + G+L EA+ +   MP++   S W A+LS       ++     A+S F   PE S     VM+S + A+ G+ +E   L   ++++G
Sbjct:    1 MRDTVCYNAMITGYSRNNDGYASIRLFCEMRQGGFRPNDFTYTTVLSGVAQIVDAEKQCQQLHCAVVKSGTGFATSVWNALLSVYVRCASSPLVSSSSLMGEARNLFNEMPERDELS-WTTMITGYIRNEDLHAARELLDGM--DERMEVVWNAMISGYAHHNSFQEALLLFRKMRLLGIHQDEFTYTSVISTCANNGQFQLGKQVHAYILRT-EAKPTVDFSLSVNNTLLTLYYKCGKLDEARYIFNNMPVKDLVS-WNAILSGYVSAGRIQ----EAKSFFKEMPERSILTWTVMISGL-AQNGLGEEAMTLFNQMRSEG 312          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGK-CVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSS-WNALIAGYMKDGEICL----AEDLFGKMP 630
            L+ G+Q+HAQ+   GF+        ++ MYA       A ++F  +    ++ +N++I A   HG   + ++++ +M    +  D  T+  +L  C+    +  G+     + +  G+  D      +I++  +C + ++A+ L + M        W AL+AG    G + L    AE LF  +P
Sbjct:  333 LEHGRQLHAQLISLGFDSSLSAANALITMYARCGVFKDANSVFLTMPCIDSVSWNAMIAALAQHGHGVQAIDLFEQMLKADILPDRITFLIILSACSHAGLVKEGRHYFSSMRVCYGISPDEGHYARMIDLLCRCGEFTEAKGLIESMPFEPGGPIWEALLAGCRTHGNMDLGIQAAERLFELVP 517          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEE-KEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            L++G+  H          D Y+   +V  Y S  DLD A  +F +      + +NS+I  +      +E +E++  M    +K ++ T   VL  CA+   +  G+ V     +  ++ ++ +  ++++MYVKC  + DA+RLFD+M  +D+ SW  ++ GY + G    A  +F  MP ++I +W  +IS Y Q+G  ++AL +F+E L+K    KP+ VT++S L ACA   A++ G  IH +  +  ++ N  + T+L+ MYAKCG L  A + F  V   + ++  W+ MI   A HG+G +A+  F  M+ A V+P+ +TFT +L  CSH+GLVD G  +F  M+ VY V PG++HYAC+VD+LGR+G L EA +LI KMP+    S+WGA+L AC+ H N+ +AE A   L  L+P N G YV+LSNIYAE G W EV  LR  ++  G+KK PGCS  EVNG  H FL GD SHP  KEIY   LDE+  ++K+ GYVP+ S +L  V EE+ K+H+L  HSEKLAIAFGL++ SP   ++V KNLR+CGDCH+  KLIS++Y+REI++RD  RFHHF+DG+CSC DYW
Sbjct:  147 LQVGRGFHGMAIKASLGSDIYILNSLVHFYGSCGDLDLARRVFMKTPKKDVVSWNSMITVFAQGNCPQEALELFKEMEAENVKPNDVTMVSVLSACAKKVDLEFGRWVCSHIQRNEIKENLTLNNAMLDMYVKCGSVDDAKRLFDRMPEKDIVSWTTMLDGYAQLGNYEEAWRVFAAMPSQDIAAWNVLISSYEQSGKPKEALAVFNE-LQKSKSPKPDEVTLVSTLAACAQLGAIDLGGWIHVYIKKQVMKLNCHLTTSLIDMYAKCGDLDKALEVFNSVE--RRDVFVWSAMIAGLAMHGQGRDALEFFSKMLEAKVKPNAVTFTNVLCACSHTGLVDEGRTFFYQMEPVYGVVPGIKHYACMVDILGRSGNLDEAVELIEKMPIPPTASVWGALLGACKLHGNVVLAEKACSHLLELDPRNHGAYVLLSNIYAETGKWDEVSGLRKHMRDAGIKKEPGCSSIEVNGSVHEFLVGDNSHPLCKEIYS-KLDEMALRLKSNGYVPNKSHLLQFVEEEDMKDHALILHSEKLAIAFGLISLSPSQPIQVVKNLRVCGDCHSVAKLISKLYDREILLRDRYRFHHFRDGHCSCNDYW 738          

Query:   19 PLLAQDPRFVSFYAPIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSD--DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM--HCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERV-----------------------------RXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVA-GVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH 1305
            P  + D RF S   P    +     +K  +QVHAQM   G   D Y  +K++   A S    LD A  +F ++  P+   +N++IRAY       E++ ++  M  HC     D +TYPF +K  +EL  + +G+  HG+++K  L SD+Y+  SL++ Y  C D+  ARR+F K   +DV SWN                               +MI+ + Q    ++AL LF EM  +   VKPN VT++SVL ACA    LE GR + +   R  ++ N+++  A+L MY KCGS+ DA++ F+R+                                  ++ AWN +I++Y   G+  EA++ F ++  +   +PD +T    L+ C+  G +D+G     Y+K+   ++        ++D+  + G L +A ++   +  +    +W AM++    H
Sbjct:   20 PTFSTDLRFSSH--PALSLIDQCTSIKQLKQVHAQMLRTGVLFDPYSASKLITASALSSFSSLDYARQVFDQIPQPNVYTWNTLIRAYASSSDPAESILVFLDMLDHCSECP-DKYTYPFAIKAASELRALQVGRGFHGMAIKASLGSDIYILNSLVHFYGSCGDLDLARRVFMKTPKKDVVSWN-------------------------------SMITVFAQGNCPQEALELFKEM--EAENVKPNDVTMVSVLSACAKKVDLEFGRWVCSHIQRNEIKENLTLNNAMLDMYVKCGSVDDAKRLFDRMPEKDIVSWTTMLDGYAQLGNYEEAWRVFAAMPSQDIAAWNVLISSYEQSGKPKEALAVFNELQKSKSPKPDEVTLVSTLAACAQLGAIDLGGWIHVYIKK-QVMKLNCHLTTSLIDMYAKCGDLDKALEVFNSVE-RRDVFVWSAMIAGLAMH 444          

Query:  142 EPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSL----KVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            E D      M+  Y  ++DL +A  +   ++    +++N++I  Y  H   +E + ++ +M  LG+  D FTY  V+  CA      +GK VH   L    K  ++  + V  +L+ +Y KC  + +AR +F+ M V+D+ SWNA+++GY+  G I  A+  F +MP R+I++WT MISG  QNGL E+A+ LF++M  +    +P        + +CA   ALE GR++H     +G +S++S   AL+ MYA+CG   DA   F  +    +  V+WN MI A A HG G +A+  FE M+ A + PD ITF  +LS CSH+GLV  G  YF  M+  Y + P   HYA ++DLL R G   EAK LI  MP + G  IW A+L+ CR H N+++   AA  LF L P++ G Y++LSN+YA  G W +V  +R L++ +GVKK PGCSW +V    H+FL GDT HP+ + +Y++ L++L  +++  GY+PDT FVLHD+  E KE+SL+THSEKLA+AFGL+    G  +RV KNLRICGDCHTA K +SR+  R+IIVRD  RFHHF++G CSCG+YW
Sbjct:  112 ERDELSWTTMITGYIRNEDLHAARELLDGMDERMEVVWNAMISGYAHHNSFQEALLLFRKMRLLGIHQDEFTYTSVISTCANNGLFQLGKQVHAYILRTEAKPTVDFSLSVNNTLLTLYYKCGKLDEARYIFNNMPVKDLVSWNAILSGYVSAGRIQEAKSFFKEMPERSILTWTVMISGLAQNGLGEEAMKLFNQM--RSEGFEPCDYAFSGAITSCAALGALEHGRQLHAQLISLGFDSSLSAANALITMYARCGVFEDANSVFLTMPYIDS--VSWNAMIAALAQHGHGVQAIDLFEKMLKADILPDRITFLIILSACSHAGLVKEGRHYFSSMRVSYGISPDEGHYARMIDLLCRCGEFTEAKGLIESMPFEPGAPIWEALLAGCRTHGNMDLGIQAAERLFELVPQHDGTYILLSNLYAAIGRWDDVAKVRQLMRDRGVKKEPGCSWIDVENMVHVFLVGDTVHPEVQAVYKY-LEQLGLEMRKLGYLPDTKFVLHDMESEHKEYSLSTHSEKLAVAFGLMKLPLGATIRVFKNLRICGDCHTAIKFMSRVVGRDIIVRDAKRFHHFRNGECSCGNYW 689          

Query:  244 TLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKC--VHGLSLKVGLESDMYVGTSLINMYVKCCD---------MSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRI----GLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMK-------------------RVYSVEPGVEHYA---------------CVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKH-HNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKE 1422
            T+ YN++I  Y+ +     ++ ++  M   G + D+FTY  VL   A++  +   +C  +H   +K G      V  +L+++YV+C           M +AR LF++M  RD  SW  +I GY+++ ++  A +L   M  R  V W AMISGY  +   ++AL LF +M  +   +  +  T  SV+  CA++   + G+++H +  R      ++ ++S+   LL +Y KCG L +AR  F  +     +LV+WN +++ Y S GR  EA S F++M    +    +T+T ++SG + +GL +  +K F+ M+                    + ++E G + +A                ++ +  R G   +A  +   MP     S W AM++A  +H H ++  ++  + L      +   ++++ +  + AG+ KE
Sbjct:    4 TVCYNAMITGYSRNNDGYASIRLFCEMRQGGFRPDDFTYTTVLSGAAQIVDVE-KQCQQLHCAVVKSGTGFATSVWNALLSVYVRCASSPLVSSSSLMGEARNLFNEMPERDELSWTTMITGYIRNEDLHAARELLDGMDERMEVVWNAMISGYAHHNSFQEALLLFRKM--RLLGIHQDEFTYTSVISTCANNGLFQLGKQVHAYILRTEAKPTVDFSLSVNNTLLTLYYKCGKLDEARYIFNNM--PVKDLVSWNAILSGYVSAGRIQEAKSFFKEMPERSI----LTWTVMISGLAQNGLGEEAMKLFNQMRSEGFEPCDYAFSGAITSCAALGALEHGRQLHAQLISLGFDSSLSAANALITMYARCGVFEDANSVFLTMPYIDSVS-WNAMIAALAQHGHGVQAIDLFEKMLKADILPDRITFLIILSACSHAGLVKE 436          

Query:  538 VRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNI----VSWTAMISGYTQ-NGLAEQALFLFDEMLKKDSKVKPN-WVTIMSVLPACAHSAALERGR---KIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACV----VDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENS--GNYVMLSNIYAEAGMWKEVDNLRVLLKAQG 1458
            +RD   +NA+I GY ++ +   +  LF +M          ++T ++SG  Q   + +Q   L   ++K  +    + W  ++SV   CA S  +       +  N  + +     +S  T ++  Y +   L  AR+  + +   +   V WN MI+ YA H    EA+  F  M + G+  D  T+T ++S C+++GL  +G +   Y+ R    +P V+    V    + L  + G+L EA+ +   MP++   S W A+LS       ++     A+S F   PE S     VM+S + A+ G+ +E   L   ++++G
Sbjct:    1 MRDTVCYNAMITGYSRNNDGYASIRLFCEMRQGGFRPDDFTYTTVLSGAAQIVDVEKQCQQLHCAVVKSGTGFATSVWNALLSVYVRCASSPLVSSSSLMGEARNLFNEMPERDELS-WTTMITGYIRNEDLHAARELLDGM--DERMEVVWNAMISGYAHHNSFQEALLLFRKMRLLGIHQDEFTYTSVISTCANNGLFQLGKQVHAYILRT-EAKPTVDFSLSVNNTLLTLYYKCGKLDEARYIFNNMPVKDLVS-WNAILSGYVSAGRIQ----EAKSFFKEMPERSILTWTVMISGL-AQNGLGEEAMKLFNQMRSEG 312          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGK-CVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICL----AEDLFGKMP 630
            L+ G+Q+HAQ+   GF+        ++ MYA     + A ++F  +    ++ +N++I A   HG   + ++++ +M    +  D  T+  +L  C+    +  G+     + +  G+  D      +I++  +C + ++A+ L + M        W AL+AG    G + L    AE LF  +P
Sbjct:  333 LEHGRQLHAQLISLGFDSSLSAANALITMYARCGVFEDANSVFLTMPYIDSVSWNAMIAALAQHGHGVQAIDLFEKMLKADILPDRITFLIILSACSHAGLVKEGRHYFSSMRVSYGISPDEGHYARMIDLLCRCGEFTEAKGLIESMPFEPGAPIWEALLAGCRTHGNMDLGIQAAERLFELVP 517          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYASSD--DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +Q+H+++   G   D     +++   A S   DL  A+ +F  + +P   +YN+++R Y         + +Y +M    +  + +T+P V++ C     I  GK VH   +K+G  +D +   +LI+MYVK   + +ARR+FDKM   D  SW  LI GY + G +  A +LF  MP +N VSW AMIS Y Q+    +A  LF +M  +  KV+ +     S+L AC    ALE+G+ IH +  + G+E +  + T ++ MY KCG L  A + F  +      + +WN MI   A HG+G  A+  FE M    V PDNITF  +LS C+HSGLV+ G +YF  M  V+ +EP  EH+ C+VDLLGRAG L EA+ LI +MPM     + GA+L AC+ H N+E+ E   R +  LEPENSG YV+L+N+YA AG W++V N+R L+  +GVKK PG S  E+ G  + F+ G  +HPQ KEIY   +DE+ K I++AGYVPDT  VLHD+ EEEKE+ L  HSEKLAIAFGLL T PG  LR++KNLR+C DCH A+KLIS++++REIIVRD NRFHHFK G+CSC DYW
Sbjct:   37 RQLHSKVIRLGLAADNDAMGRVIKFCALSKNGDLGYALQVFDTMLHPDAFIYNTVMRGYLQCHLPRNCIVLYSQMLQDSVTPNKYTFPSVIRACCNDDAIGEGKQVHAHVVKLGYGADGFCQNNLIHMYVKFQSLEEARRVFDKMLRMDAVSWTTLITGYSQCGFVDEAFELFELMPEKNSVSWNAMISSYVQSDRFHEAFALFQKM--RVEKVELDKFMAASMLSACTGLGALEQGKWIHGYIEKSGIELDSKLATTIIDMYCKCGCLEKAFEVFNGL--PHKGISSWNCMIGGLAMHGKGEAAIELFEKMQRDMVAPDNITFVNVLSACAHSGLVEEGQRYFQSMVEVHGIEPRKEHFGCMVDLLGRAGMLEEARKLISEMPMSPDVGVLGALLGACKIHGNVELGEHIGRIVIELEPENSGRYVLLANLYANAGRWEDVANVRRLMNDRGVKKVPGFSMIELEGVVNEFIAGGGAHPQTKEIYA-KVDEMLKCIRSAGYVPDTEGVLHDLDEEEKENPLYYHSEKLAIAFGLLKTKPGETLRISKNLRVCKDCHQASKLISKVFDREIIVRDRNRFHHFKRGDCSCKDYW 624          

Query:   58 APIFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKV-GLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVR-DVSSWNALIAGYMKDGEICLAEDL 615
            A +  + TG   L+ G+ +H  +   G E D+ L   ++ MY     L+ A  +F+ + +     +N +I    +HG  E  +E++ +M    +  DN T+  VL  CA    +  G+      ++V G+E        ++++  +   + +AR+L  +M +  DV    AL+      G + L E +
Sbjct:  256 ASMLSACTGLGALEQGKWIHGYIEKSGIELDSKLATTIIDMYCKCGCLEKAFEVFNGLPHKGISSWNCMIGGLAMHGKGEAAIELFEKMQRDMVAPDNITFVNVLSACAHSGLVEEGQRYFQSMVEVHGIEPRKEHFGCMVDLLGRAGMLEEARKLISEMPMSPDVGVLGALLGACKIHGNVELGEHI 443          

Query:  106 QQVHAQMALRGFEPDAYLGAKMVAMYAS-SDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +Q+HA + ++   P   L    +A   S +     A  IF  + NP  L +NS ++A+       + + ++ ++    +  D+FT  FVLK C  L  +  G+ +HG   K+G +S++++   ++N+Y  C ++ DAR LFDKM+ RDV +WN ++   +K G+I  A DLF +MP R++ SWT MISG+ Q G  ++A+ LF EM  +++ V+PN VT+++VL ACA    L  GR+IH ++++ G   N  I   L+ MY KCG L DA   F+ ++  +  +V+W+ MI   A HG+  EA+  F  MI  G+ P+++TF GLL  CSH G V  G ++F  M   Y + P +EHY C+VDLL RAG L EA + I  MP++    +WGA+L  C+ H N+E+AE A + L  L+P N G YV+LSNIYAEA  W++   +R L++ +GVKK PG S   V+G  H F+ GD  HPQA+EI++ + ++L  K+K  GYVP+TS VL D+ E++KE  L  HSEKLA+ FGL+NT PG  +R+ KNLR+C DCH A KLIS I  REI+VRD NRFH FKDG+CSC DYW
Sbjct:   26 KQLHAHL-IKTNTPLTSLPLTRIAFVCSLNPSFSYAQKIFKHLENPEILAWNSCLKAFAEGKDPIDAVMLFYQLQSFHVLPDSFTLSFVLKACTRLLDVSNGRVLHGYVEKLGFQSNLFLMNMILNLYALCGEVRDARLLFDKMSHRDVVTWNIMMTQLVKRGDIKEAYDLFSRMPKRSVRSWTLMISGFVQCGKPKEAISLFLEM--EEAGVRPNEVTVVAVLAACADLGDLGLGRRIHEYSNQSGFSRNARISNTLIEMYVKCGCLEDASTVFDGMK--ERTVVSWSAMIAGLAMHGQAEEALRLFSRMIQTGMDPNDVTFVGLLHACSHIGFVAQGREFFTSMTNDYGIVPRIEHYGCMVDLLSRAGLLQEAYEFITNMPIKPNSIVWGALLGGCKVHRNIELAEEATKHLSELDPLNDGYYVVLSNIYAEAQRWEDTARVRKLMRDRGVKKTPGWSSITVDGVIHEFVAGDEVHPQAQEIFQ-MWEKLVVKMKLKGYVPNTSVVLLDMEEDQKEKFLYRHSEKLALVFGLMNTGPGTPIRIMKNLRVCEDCHAAFKLISAIVNREIVVRDRNRFHCFKDGSCSCRDYW 611          

Query:  103 GQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRM----------------HC---------------LGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIH-NFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASH 996
            G+ +H  +   GF+ + +L   ++ +YA   ++  A  +F ++++   + +N ++      G  +E  +++ RM                 C                G++ +  T   VL  CA+L  + +G+ +H  S + G   +  +  +LI MYVKC  + DA  +FD M  R V SW+A+IA                               G   +G AE+AL LF  M++  + + PN VT + +L AC+H   + +GR+   +  +  G+   +     ++ + ++ G L +A +    +    N++V W  ++     H
Sbjct:  126 GRVLHGYVEKLGFQSNLFLMNMILNLYALCGEVRDARLLFDKMSHRDVVTWNIMMTQLVKRGDIKEAYDLFSRMPKRSVRSWTLMISGFVQCGKPKEAISLFLEMEEAGVRPNEVTVVAVLAACADLGDLGLGRRIHEYSNQSGFSRNARISNTLIEMYVKCGCLEDASTVFDGMKERTVVSWSAMIA-------------------------------GLAMHGQAEEALRLFSRMIQ--TGMDPNDVTFVGLLHACSHIGFVAQGREFFTSMTNDYGIVPRIEHYGCMVDLLSRAGLLQEAYEFITNMPIKPNSIV-WGALLGGCKVH 421          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGK-CVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVS-SWNALIAGYMKDGEICLAED 612
            L LG+++H      GF  +A +   ++ MY     L+ A  +F  +   + + ++++I    +HG +EE + ++ RM   G+  ++ T+  +L  C+ +  +  G+     ++   G+   +     ++++  +   + +A      M ++  S  W AL+ G      I LAE+
Sbjct:  255 LGLGRRIHEYSNQSGFSRNARISNTLIEMYVKCGCLEDASTVFDGMKERTVVSWSAMIAGLAMHGQAEEALRLFSRMIQTGMDPNDVTFVGLLHACSHIGFVAQGREFFTSMTNDYGIVPRIEHYGCMVDLLSRAGLLQEAYEFITNMPIKPNSIVWGALLGGCKVHRNIELAEE 429          

Query:   94 LKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNI----VSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            L+  +++H +    GF  D  LG  MV M+     +D A  +F  +     + + S+   Y   G   E +  +  M   G++ +  T   +L  C+EL  + +G+ +HG  +K  +E +++V ++L+N+Y  C  +  A+ +FD M  RDV SWN L+  Y  + +      LF +M    +     SW A+I G   NG  EQAL +  +M  ++S  KPN +TI S+LPAC    +L  G+++H++  R  L  +++  TAL+ MYAKCG L  +R+ F+ +   + + VAWNTMI A + HG G EA+  F  M+ + V+P+++TFTG+L GCSHS LVD G+  FD M+R +SVEP  +HY+C+VD+L RAG L EA   I +MPM+  P  WGA+L ACR H N+++A+IAA  LF +EP+N GNYV+LSNI   A  W+E    R L++ +GV K PGCSW ++  + + F+ GD S+ +++E+Y+FL+ E+ +K++ AGYVP+T FVL DV +EEK   L  HSEKLA+AFG+LN +    +RV KNLRICGDCH A K + +I   +IIVRD  RFHHFKDG+CSC D+W
Sbjct:   93 LRDAKELHDEAIRFGFHSDIALGNAMVDMFGKCKYVDGARQVFDDMPAKDVVSWTSLCSCYVNCGLPREGLVAFREMGLNGVRPNAVTVSSILPACSELKDVNLGREIHGFVVKHAMEENVFVSSALVNIYASCLSIKQAQMVFDMMPQRDVVSWNVLLTAYFSNRDCEKGIALFCRMRREGVKLDGASWNAVIGGCLNNGQTEQALKMLGQM--QESGFKPNQITITSLLPACKDLESLRAGKEVHSYIFRNCLMEDLATTTALVFMYAKCGELELSRRVFDMM--PRRDTVAWNTMIIANSMHGNGEEALLLFRKMLDSRVKPNSVTFTGVLCGCSHSRLVDEGIMVFDSMRRDHSVEPDADHYSCMVDVLSRAGHLEEAYQFIQRMPMEPTPGAWGALLGACRVHKNVDLAKIAANRLFEIEPDNPGNYVLLSNILVTAKRWEEASETRKLMRDRGVTKTPGCSWVQLRNRVYSFVAGDRSNERSEEMYKFLV-EMGEKMRLAGYVPNTDFVLQDVDQEEKVGILCNHSEKLAVAFGILNLNGESTIRVFKNLRICGDCHNAIKFMGKIVGVQIIVRDSLRFHHFKDGDCSCRDFW 686          

Query:  151 AYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYGRMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMK 1143
            ++L  + + +  +S DL  A  +F ++ +P    +  +I  +T HGF +E++++Y  +    +  DN     V K CA L  +   K +H  +++ G  SD+ +G ++++M+ KC  +  AR++FD M  +DV SW                               T++ S Y   GL  + L  F EM    + V+PN VT+ S+LPAC+    +  GR+IH F  +  +E NV + +AL+ +YA C S+  A+  F+ +   Q ++V+WN ++TAY S+    + ++ F  M   GV+ D  ++  ++ GC ++G  +  LK    M+
Sbjct:   11 SHLSLRFLKICCNSGDLQRARHLFDQIPHPDLRAWTVLISGHTRHGFPKESIKLYTSLRGRHIVPDNLLLLSVAKACASLGDLRDAKELHDEAIRFGFHSDIALGNAMVDMFGKCKYVDGARQVFDDMPAKDVVSW-------------------------------TSLCSCYVNCGLPREGLVAFREM--GLNGVRPNAVTVSSILPACSELKDVNLGREIHGFVVKHAMEENVFVSSALVNIYASCLSIKQAQMVFDMM--PQRDVVSWNVLLTAYFSNRDCEKGIALFCRMRREGVKLDGASWNAVIGGCLNNGQTEQALKMLGQMQ 306          

Query:   64 IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSD--DLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETME---IYGRMHCLGLKXDN-FTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTV-----------RDVSSWNALIAGYMKDGEICLAEDLFGKMPGRNIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            +F  +T    ++   QVHA         D    A+++  YA S   +++ A A+F+ +  P+   +N+IIRA       E  +E   ++ +M   G    N FT+P VLK CA++  + +GKCVHG+ +K GL++D +V ++L+ MYV C  M DA  LF +  V            +V  WN ++ GY++ G++  A  LF KMP R++VSW  MISGY QNG   +A+ LF +M  +   V PN+VT++SVLPA +   ALE G+ IH +A +  +E +  + +AL+ MY+KCGS+  A   FE++   + N++ WN +I+  A HGR  +A+  F+ M  AGV P ++T+ G+LS CSH+GLV+ G  +F+ M  V S+EP +EHY C+VDLLGRAG L EA++LI  MP+Q     W A+L AC+K  N+++ +  A  L  L P +SG+YV LSN+YA  G W+ V  +R+ +K   ++K+PG S  E++G  H F+  D SHP+A+EI+  +L+E+  ++   G+ PDT+ VL ++ EEEK+  L  HSEK+A AFGL++T+P   LR+ KNLRIC DCH++ KLIS+IYER IIVRD  RFHHF+ G CSC DYW
Sbjct:   19 LFPQITACKTIRDLHQVHALFIKTRQIHDPLAAAEILRFYALSAHRNIEWARAVFNHMQRPNCFSWNTIIRALAESSVDEHPLEALLLFSQMVSYGFVGPNRFTFPSVLKACAKMGNLGVGKCVHGMVVKFGLDTDEFVVSNLVRMYVMCKVMEDAHLLFSRSVVVCGHLNERKQEGNVVLWNVIVDGYVRVGDVRAARVLFDKMPQRSVVSWNVMISGYAQNGFFREAIDLFRDM--QIENVYPNYVTLVSVLPAISRLGALELGKWIHLYAGKNRIEIDDVLGSALVDMYSKCGSIEKALLVFEKL--PKRNVITWNAIISGLAMHGRVEDALDYFKKMEPAGVVPSDVTYIGILSACSHAGLVEQGRSFFNRMVNVISLEPRIEHYGCMVDLLGRAGLLEEAEELILNMPIQPDDVTWKALLGACKKQGNIDMGKRVAEVLMDLAPHDSGSYVALSNMYASLGNWEAVAKVRLQMKDMDIRKDPGGSSIELDGVIHEFVVEDESHPRAREIHS-MLEEISNQLSLEGHRPDTTQVLLNMDEEEKQSVLHYHSEKIATAFGLISTAPQTPLRIVKNLRICEDCHSSLKLISKIYERMIIVRDRKRFHHFEQGLCSCMDYW 635          

Query:   49 SFYAP-IFQSLTGKNLLKLGQQVHAQMALRGFEPDAYLGAKMVAMYASSDDLDSAVAIFHRVNNPSTLLYNSIIRAYTLHGFSEETMEIYG-----------------------------------RMHCLGLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAKDLIXKMPMQAGPSIWGAMLSACRKHHNLEIAEIAARSLFILEPENSGNYVMLSNIYAEAGMWKEVDNLRVLLKAQGVKKNPGCSWTEVNGKAHLFLGGDTSHPQAKEIYEFLLDELPKKIKAAGYVPDTSFVLHDVSEEEKEHSLTTHSEKLAIAFGLLNTSPGVVLRVTKNLRICGDCHTATKLISRIYEREIIVRDLNRFHHFKDGNCSCGDYW 1878
            SF  P + ++  G    K G+QVHA  ++ G   D+++ + +V MY   D +  A  +F RV     ++ +++I  Y+  G  +E M++                                     +MH  G + D  +    L     L  + +G  +HG  +K GL SD  V ++LI+MY KC    +  ++F +M   DV + NAL+ G  ++G +  A  +F +   +    NIVSWT++I+  +QNG   +AL LF EM  +   V+PN VTI  +LPAC + AAL  G+  H F+ R G+ ++V + ++L+ MYAKCG +  +R CF+ +     NLV WN ++  YA HG+ +E +  F  M  +G +PD I+FT +LS CS  GL D G  YF+ M + + +E  VEHYAC+V LL R+G+L EA  +I +MP +    +WGA+LS+CR H N+ + +  A+ LF LEP+N GNY++LSNIYA  GMW EVD +R  +K+ G++KNPGCSW EV  K H+ L GD +HPQ  +I E  L++L  ++K  GY P+T FVL DV E++KE  L  HSEKLA+  GLLN+ PG  LRV KNLRICGDCH   K IS    REI VRD N FHHFKDG CSC DYW
Sbjct:   10 SFLFPSVVKACAGLPASKAGKQVHAIASVSGLASDSFVQSSLVHMYIKCDQIRDARKLFDRVPQRDVIICSALISGYSRRGCVDEAMQLLSEMRGMCLEPNVVLWNGMIAGFNQSKLYADTVAVLQKMHSEGFQPDGSSISSALPAVGHLEDLGMGIQIHGYVVKQGLGSDKCVVSALIDMYGKCACSFETSQVFHEMDQMDVGACNALVTGLSRNGLVDNALKVFRQFKDQGMELNIVSWTSIIASCSQNGKDMEALELFREMQVEG--VEPNSVTIPCLLPACGNIAALMHGKAAHCFSLRRGISNDVYVGSSLIDMYAKCGKIRLSRLCFDEM--PTRNLVCWNAVMGGYAMHGKANETMEVFRLMQRSGQKPDFISFTCVLSACSQKGLTDEGWYYFNSMSKEHGLEARVEHYACMVTLLSRSGKLEEAYSMIKQMPFEPDACVWGALLSSCRVHSNVTLGKYVAKKLFNLEPKNPGNYILLSNIYASKGMWSEVDKVRDKMKSLGLRKNPGCSWIEVKNKVHMLLAGDKAHPQMNQIIE-KLNKLSSEMKKLGYFPNTHFVLQDVEEQDKEQILCGHSEKLAVVLGLLNSPPGSSLRVIKNLRICGDCHAVIKFISSFEGREISVRDTNLFHHFKDGVCSCEDYW 654          

Query:  334 GLKXDNFTYPFVLKCCAELSRIWIGKCVHGLSLKVGLESDMYVGTSLINMYVKCCDMSDARRLFDKMTVRDVSSWNALIAGYMKDGEICLAEDLFGKMPGR----NIVSWTAMISGYTQNGLAEQALFLFDEMLKKDSKVKPNWVTIMSVLPACAHSAALERGRKIHNFASRIGLESNVSIQTALLAMYAKCGSLLDARQCFERVRXTQNNLVAWNTMITAYASHGRGSEAVSTFEDMIVAGVQPDNITFTGLLSGCSHSGLVDVGLKYFDYMKRVYSVEPGVEHYACVVDLLGRAGRLAEAK 1230
            GL  D+F +P V+K CA L     GK VH ++   GL SD +V +SL++MY+KC  + DAR+LFD++  RDV   +ALI+GY + G +  A  L  +M G     N+V W  MI+G+ Q+ L    + +  +M       +P+  +I S LPA  H   L  G +IH +  + GL S+  + +AL+ MY KC    +  Q F  +   Q ++ A N ++T  + +G    A+  F      G++ + +++T +++ CS +G     L+ F  M +V  VEP      C++   G    L   K
Sbjct:    5 GLVPDSFLFPSVVKACAGLPASKAGKQVHAIASVSGLASDSFVQSSLVHMYIKCDQIRDARKLFDRVPQRDVIICSALISGYSRRGCVDEAMQLLSEMRGMCLEPNVVLWNGMIAGFNQSKLYADTVAVLQKM--HSEGFQPDGSSISSALPAVGHLEDLGMGIQIHGYVVKQGLGSDKCVVSALIDMYGKCACSFETSQVFHEM--DQMDVGACNALVTGLSRNGLVDNALKVFRQFKDQGMELNIVSWTSIIASCSQNGKDMEALELFREM-QVEGVEPNSVTIPCLLPACGNIAALMHGK 302