MDP0000225534, MDP0000225534 (mRNA) Malus spp. (apple)

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            L+PGTKYYYKCGDSS PAMS+E+  ETLP PG   YPRRIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYN TGAQYAWLK DLH+VDR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLD CGP+YITVGDGGNIE+V+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQ+YIVRQP LCS ++KV++
Sbjct:  140 LEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQPHLCSTASKVVA 525          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            L+PGTKYYYKCGDSS PAMS+E+  ETLP PG   YPRRIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYN TGAQYAWLK DLH+VDR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLD CGP+YITVGDGGNIE+V+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQ+YIVRQP LCS ++KV++
Sbjct:  154 LEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQPHLCSTASKVVA 539          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+PGTKY+YKCGDSSIPAMS+EH  ETLP P  N YP RIA++GDLGLTSN+STTIDH+I NDPSMILMVGDL YANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITF+SYLTR+AVPSEE GS SNFYYSFDAGG+HF+MLGAY+DYN+TGAQY+WLK DL++VDR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNYTLDPCGP+YITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQ+Y+VRQPELC
Sbjct:  127 GLEPGTKYFYKCGDSSIPAMSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPELC 505          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAK 1641
            GL+PGT+YYYKCGDSSIPAMSQEH  ET P+P  N YP RIAV+GDLGLTSN+++TIDHL  NDPSMILMVGDL YANQY TTGGKGASC+SCAFPDAPIRETYQPRWDGWGRFMEPLTS +PMMVIEGNHEIEPQ  GITF+SYLTRFAVP+EE GSKSNFYYSFDAGG+HFIMLGAY+DYN+TGAQ+AWLK DL  VDR+VTPWLVAAWH PWYNSY+SHYQEFECMR EME LL++Y VDIVF GHVHAYERMNRV+NYTLDPCGP+YITVGDGGNIE+VDVD ADDPGKCPSAGDN PEFGGVC  NFS+GPAKGNFCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YKE++ GDQ+YIVRQPELC +  K
Sbjct:  156 GLEPGTRYYYKCGDSSIPAMSQEHYFETFPKPSPNNYPARIAVIGDLGLTSNSTSTIDHLNYNDPSMILMVGDLTYANQYLTTGGKGASCYSCAFPDAPIRETYQPRWDGWGRFMEPLTSEIPMMVIEGNHEIEPQAGGITFKSYLTRFAVPAEESGSKSNFYYSFDAGGIHFIMLGAYVDYNSTGAQFAWLKKDLQSVDRSVTPWLVAAWHSPWYNSYASHYQEFECMRLEMEELLFRYRVDIVFDGHVHAYERMNRVFNYTLDPCGPVYITVGDGGNIEKVDVDHADDPGKCPSAGDNIPEFGGVCKSNFSTGPAKGNFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDNYKENAVGDQIYIVRQPELCMKDLK 539          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWG-----------------------------------RFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKV 1644
            GL+PGT+YYYKCGDSSIPAMSQE+  ET  +P    YP RIAV+GDLGLTSN+STT+DHL  NDPSMILM+GDL YANQY TTGGKGASCFSCAFPDAPIRETYQPRWDGWG                                   RFM+PLTS+VPMMVIEGNHEIEPQ  GITF+SYLTRFAVP+EE GSKSNF+YSFD GG+HFIMLGAY+DYN TGAQ+ WLK DL  VDR+VTPWLVA  HPPWYNSY+SHYQEFECMR EMEALLYQY VDI+F+GHVHAYERMNRVYNYTLDPCGP+YITVGDGGNIE+VDVD AD+PGKCPS+GDN PEFGGVCH NF+ GPAKGNFCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD+YKE++ GDQ+YIVRQPELC + +K+
Sbjct:  155 GLEPGTRYYYKCGDSSIPAMSQENYFETFAKPSPKNYPARIAVIGDLGLTSNSSTTVDHLSYNDPSMILMIGDLTYANQYLTTGGKGASCFSCAFPDAPIRETYQPRWDGWGSNCFPKLSTSVTSAYASRISSKDRWYDLLIRCLTIRFMQPLTSKVPMMVIEGNHEIEPQADGITFKSYLTRFAVPAEESGSKSNFFYSFDTGGIHFIMLGAYVDYNKTGAQFDWLKKDLQNVDRSVTPWLVATMHPPWYNSYASHYQEFECMRLEMEALLYQYRVDIIFNGHVHAYERMNRVYNYTLDPCGPIYITVGDGGNIEKVDVDHADEPGKCPSSGDNIPEFGGVCHSNFTFGPAKGNFCWKKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDSYKENAVGDQIYIVRQPELCFKDSKL 574          

Query:  490 GLKPGTKYYYKCGDSSIPA-MSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL P T+YYY+CGDSS+ A +S+E +  TLP P    YPRR+AVVGDLGLT N+++T+DHL +NDPS++LMVGD+ YANQYRTTGG+G  CFSC+FPDAPIRE+YQPRWDGW RFMEPL SR+PMMVIEGNHEIEPQ  G  +TF SY  RFAVP+EE GS S FYYSFDAGG+HFIMLGAY+DYN TGAQY+WLK DL RVDR VTPW+VA+WH PWYNSYSSHYQEFECMRQEME LLYQ+ VDIVFSGHVHAYERMNRV+NYTLDPCGP+YI +GDGGNIE++D+D ADDPGKCPS GDN PEFGG+CHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY EDS GDQ+YIVRQP+ C
Sbjct:  145 GLAPSTRYYYRCGDSSLKAGLSEERSFTTLPAPAPGAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSLVLMVGDMTYANQYRTTGGRGVPCFSCSFPDAPIRESYQPRWDGWARFMEPLASRIPMMVIEGNHEIEPQGHGGAVTFASYSARFAVPAEESGSNSKFYYSFDAGGIHFIMLGAYVDYNRTGAQYSWLKKDLQRVDRAVTPWVVASWHSPWYNSYSSHYQEFECMRQEMEGLLYQHRVDIVFSGHVHAYERMNRVFNYTLDPCGPVYIIIGDGGNIEKIDIDHADDPGKCPSPGDNHPEFGGLCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEDSVGDQIYIVRQPDKC 526          

Query:  490 GLKPGTKYYYKCGDSSI---PAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+     +S E + ETLP      YPRR+AVVGDLGLT N+++T++HL +NDPS++++VGD+ YANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNHEIEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL ++DR VTPW+VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLDPCGP+YIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQ+YIVRQP+ C
Sbjct:  174 GLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHEIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWVVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSI---PAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+     +S E + ETLP      YPRR+AVVGDLGLT N+++T++HL +NDPS++++VGD+ YANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNH+IEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL ++DR VTPW VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLDPCGP+YIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQ+YIVRQP+ C
Sbjct:  174 GLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHDIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWAVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSIPA-MSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+   +S E +  TLP P  + YPRR+AVVGDLGLT N+++T+DHL +NDPSMILMVGD+ YANQY TTGG+G  CFSC+FPDAPIRE+YQPRWDGWGRFMEPLTS+VPMMV EGNHEIEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL +VDR VTPW+VA+WH PWYNS SSHYQEFECMRQEME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLD CGP+YIT+GDGGNIE++D D ADDPG CPS GDN PEFGGVCHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY E S GD++YIVR+P+ C
Sbjct:  174 GLRPSTRYYYRCGDSSLKGGLSDERSFRTLPAPAPDAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSMILMVGDMTYANQYLTTGGRGVPCFSCSFPDAPIRESYQPRWDGWGRFMEPLTSKVPMMVTEGNHEIEPQGHGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLQKVDRRVTPWVVASWHSPWYNSCSSHYQEFECMRQEMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDSCGPVYITIGDGGNIEKIDTDHADDPGSCPSPGDNQPEFGGVCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEHSVGDEIYIVREPDKC 555          

Query:  490 GLKPGTKYYYKCGDSSIPA-MSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+   +S E +  TLP P  + YPRR+AVVGDLGLT N+++T+DHL +NDPSMILMVGD+ YANQY TTGG+G  CFSC+FPDAPIRE+YQPRWDGWGRFMEPLTS+VPMMV EGNHEIEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL +VDR VTPW+VA+WH PWYNS SSHYQEFECMRQEME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLD CGP+YIT+GDGGNIE++D D ADDPG CPS GDN PEFGGVCHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY E S GD++YIVR+P+ C
Sbjct:  171 GLRPSTRYYYRCGDSSLKGGLSDERSFRTLPAPAPDAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSMILMVGDMTYANQYLTTGGRGVPCFSCSFPDAPIRESYQPRWDGWGRFMEPLTSKVPMMVTEGNHEIEPQGHGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLQKVDRRVTPWVVASWHSPWYNSCSSHYQEFECMRQEMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDSCGPVYITIGDGGNIEKIDTDHADDPGSCPSPGDNQPEFGGVCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEHSVGDEIYIVREPDKC 552          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            L+PGTKYYYKCGDSS PAMS+E+  ETLP PG   YPRRIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYN TGAQYAWLK DLH+VDR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLD CGP+YITVGDGGNIE+V+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQ+YIVRQP LCS ++KV++
Sbjct:  140 LEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQPHLCSTASKVVA 525          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEF-GGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GLKP T+YYY+CGD +I AMS  ++  T+P  G  +YPR+I ++GDLGLT N++ TIDHLI N P ++L+VGD+ YANQY  T G G+ C+SC+FP  PI ETYQPRWD WGRFM+ L S+VPMMVIEGNHEIE Q     F +Y +RFA PS+E GS S FYYSF+AGG+HFIMLGAY  YN +  QY WL+ DL +VDR++TPWL+AAWHPPWY+SY +HY+E ECMRQEME LLY YGVDIVF+GHVHAYER NRVYNYTLDPCGP++I VGDGGN E++ ++ AD PGKCP        F GG C  NF+ GPA G FCW +QP++SAFRESSFGHGILEV N T+ALWTW+RNQD+   D+ GDQ+YIVR P++C
Sbjct:  150 GLKPSTRYYYRCGDPTIGAMSNIYSFRTMPVSGPRSYPRKIGIIGDLGLTYNSTATIDHLISNKPDLVLLVGDVTYANQY-LTNGTGSDCYSCSFPQTPIHETYQPRWDYWGRFMQNLVSKVPMMVIEGNHEIEEQAEKKNFVAYSSRFAFPSKESGSASTFYYSFNAGGIHFIMLGAYAAYNKSADQYKWLERDLAKVDRSITPWLIAAWHPPWYSSYKAHYREVECMRQEMEELLYSYGVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIMVGDGGNREKMAIEHADAPGKCPEPSTTPDTFIGGFCATNFTFGPAAGKFCWDRQPDFSAFRESSFGHGILEVKNDTWALWTWYRNQDS--RDNAGDQIYIVRTPDMC 526          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPE--FGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVI 1647
            GLKP T YYY+CGD+SIPA+S  H  +T+   G   YP RIAVVGDLGLT NT++TI HL+ N+P +I+ VGD+CYAN Y  T G G+ C+SC+F   PI ETYQPRWD WGRFM+PL S++P+MV+EGNHEIE Q    TF +Y +RFA PS+E GS S FYYSF+AGG+HFIMLGAYI Y+ +G QY WL+ DL +VDR VTPW+VA WHPPWY++Y +HY+E ECMR  +E LLY YGVDIVFSGHVHAYER NRVYNYTLDPCGP++ITVGDGGN E++ +  AD+ G+CP     TP+   GG C  NF+SGPA G FCW +QP++SA+RE+SFGHGILE+ N T ALWTWHRNQD Y  +  GDQ+YIVRQP+ C    KVI
Sbjct:  154 GLKPETVYYYQCGDASIPALSDIHHFKTMVASGPRGYPNRIAVVGDLGLTYNTTSTISHLMSNNPDLIVFVGDVCYANMY-LTNGTGSDCYSCSFSQTPIHETYQPRWDYWGRFMQPLISKIPIMVVEGNHEIEEQAENQTFVAYSSRFAFPSKESGSSSTFYYSFNAGGIHFIMLGAYISYDKSGEQYKWLERDLKKVDRKVTPWMVATWHPPWYSTYKAHYREAECMRVALEDLLYNYGVDIVFSGHVHAYERSNRVYNYTLDPCGPVHITVGDGGNREKMAIPHADEHGQCPEP-STTPDKYMGGFCAFNFTSGPAAGRFCWDRQPDYSAYRETSFGHGILEMKNETVALWTWHRNQDFY--NLAGDQIYIVRQPDRCPVETKVI 537          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEP-QVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYI 1605
            L+  T YYY+CG         E  L+T P      +P   AV  DLG T  T +T+DH+   +  + L+ GDL YA+                          Q RWD +G  ++PL S  P MV EGNHE E        FESY +R+ +P +E GS SN YYSF+  GVH +MLG+Y  Y+    QY+WLK DL RVDR  TPWL+   H PWYNS  +H  E + M + +E LLY   VD+VF+GHVHAYER  RVYN   DPCGP++IT+GDGGN E +   + D                                    QPEWS FRE+SFGHG L++VN T+A W+WHRN D   E    D+V+I
Sbjct:  108 LEHDTIYYYRCG-----GQGPEFQLKTPPAQ----FPITFAVAADLGQTGWTKSTLDHIDGCNYDVHLLPGDLSYADYL------------------------QRRWDTFGELVQPLASARPWMVTEGNHEQENIPFFKDGFESYNSRWTMPYQESGSPSNLYYSFEVAGVHVVMLGSYAAYDLNSNQYSWLKTDLSRVDRKRTPWLLVLLHVPWYNSNKAHQGEGDRMMETLEPLLYAANVDLVFAGHVHAYERSKRVYNGRSDPCGPIHITIGDGGNREGLATRYND-----------------------------------PQPEWSVFREASFGHGELKIVNLTHAFWSWHRNDD--DEPVRSDEVWI 409          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1569
            L+ GT YYY+CG S      QE   +T P    +++P   AVVGDLG T  T++T+ H+ + +  ++L+ GDL YA                        +++QP WD +GR +EP  S  P MV EGNHEIE  P +    F+++ +R+ +P +E GS SN YYSF+  G H IMLG+Y +++   AQY WLK DL +VDR  TPWL+   H PWYN+  +H  E E MR+ ME LLY+  VD+VF+GHVHAYER  RVY    D CGP+++T+GDGGN E + + F     K  SA                                S +RE SFGHG L ++N T+A W+WHRN D+
Sbjct:  190 LEAGTVYYYRCGGSG-----QEFYFKTPP----SSFPIEFAVVGDLGQTEWTASTLTHVNRTNYDVLLLPGDLSYA------------------------DSHQPLWDCFGRLVEPYASHRPWMVTEGNHEIEIFPIIYPDGFKAFNSRWPMPFQESGSTSNLYYSFEVAGCHVIMLGSYAEFDEKSAQYKWLKGDLGKVDRRRTPWLIVLIHAPWYNTNLAHKGEGESMRKAMEKLLYEARVDVVFAGHVHAYERFTRVYKNKADECGPIHVTIGDGGNREGLALTFE----KPTSA------------------------------SLSVYREPSFGHGRLRILNQTHAFWSWHRNNDS 483          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEP--QVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHY--QEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            L   T YYY+CG S       E + +T P    + +P R+AV GD G T  T +T+DH+ +++  ++L+ GDL YA                        + YQP WD +GR +EPL S+ P M   GNH++E    V    F SY  R+ +P EE GS SN YYSF+  GVH ++LG+Y D+ +   QY WL+ DL +VDR  TPWLV   H PWYNS S+H   +E + MR  ME +LY+  VD+VF+GHVHAYER +RVY    D CGP+YIT+GDGGN E +   + D                                    +P+ S FRE+SFGHG L VV+     WTWHRN D
Sbjct:  113 LNANTVYYYRCGSSG-----PEFSFKTPP----SQFPIRLAVAGDFGQTEWTKSTLDHISKSNYDLLLLAGDLSYA------------------------DFYQPLWDSFGRLVEPLASQRPWMTATGNHDVEKIIVVHPEKFTSYNARWHMPFEESGSTSNLYYSFEVAGVHVVVLGSYTDFGSDSDQYKWLQADLGKVDRKRTPWLVVMLHAPWYNSNSAHQGEEESDGMRDSMEEILYKARVDVVFAGHVHAYERFDRVYQGKTDKCGPVYITIGDGGNREGLATKYND-----------------------------------PKPDISLFREASFGHGQLNVVDENTMEWTWHRNDD 406          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEP--QVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHY--QEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            L   T YYY+CG S       E + +T P    + +P RIAV GD G T  T +T+DH+ +++  ++L+ GDL YA                        + YQP WD +GR +EPL S+ P M   GNH++E    V      SY  R+ +P EE GS SN YYSF+  GVH ++LG+Y D+ +   QY WL+ DL +VDR  TPWLV   H PWYNS S+H   +E + MR  ME +LY+  VD+VF+GHVHAYER +RVY    D CGP+YIT+GDGGN E +   + D                                    +P+ S FRE+SFGHG L VV+     WTWHRN D
Sbjct:  523 LNANTVYYYRCGSSG-----PEFSFKTPP----SQFPIRIAVAGDFGQTEWTKSTLDHISKSNYDLLLLAGDLSYA------------------------DFYQPLWDSFGRLVEPLASQRPWMTATGNHDVEKIIVVHPEKCTSYNARWHMPFEESGSTSNLYYSFEVAGVHVVVLGSYSDFGSDSDQYKWLQADLGKVDRKRTPWLVVMLHAPWYNSNSAHQGEEESDGMRDSMEEILYKARVDVVFAGHVHAYERFDRVYQGKTDKCGPVYITIGDGGNREGLATKYID-----------------------------------PKPDISLFREASFGHGQLNVVDGNTMEWTWHRNDD 816          

Query:  487 HGLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRV----YNYTL-------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYK 1575
            HGL+P TKYYYK GD      S+E   +T P+   +T      ++GDLG T N+ +T++H +Q+    +L VGDL YA++Y              F D  +R      WD WGRF+E   +  P +   GNHE+E  P +  +  F+SYL R+A P     S +  +Y+      H I+L +Y  +     Q+ WL+++L RVDR  TPWL+   H P Y+S  +HY E E MR   E+      VD++F+GHVHAYER  R+    YN T        D   P+YITVGDGGN E +   F D                                    QPE+S+FRE+S+GH  LE+ N T+A + W+RN D  K
Sbjct:  128 HGLEPDTKYYYKIGDGG---SSREFWFQTPPKIDPDT-SYTFGIIGDLGQTYNSLSTLEHYMQSGAQTVLFVGDLSYADRYE-------------FNDVGVR------WDSWGRFVERSAAYQPWIWTAGNHEVEYMPNMGEVLPFKSYLHRYATPYMASQSSNPLWYAVRRASAHIIVLSSYSPFVKYTPQWKWLREELKRVDREKTPWLIVLMHAPMYSSNVAHYMEGESMRAVFESWFVHAKVDLIFAGHVHAYERSYRISNIHYNITNGDRYPIPDKSAPVYITVGDGGNQEGLAGRFVDP-----------------------------------QPEYSSFREASYGHSTLEIKNRTHAFYHWNRNDDGKK 446          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPS--MILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSG-ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTL-----------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY--KEDS 1584
            L+  TKYYY  G    P   ++    T P+ G +  P    ++GDLG + +++ T+ H   N      +L VGDL YA+ Y                  P  +    RWD WGRF E  T+  P +   GNHEI+  P++   I F+ Y  R+ VP     S + F+YS      + I+L +Y  Y     QY WL+ +L +V+R+ TPWL+   H PWYNSY+ HY E E MR   E    QY VD+VF+GHVHAYER  RV N              D   P+YIT+GDGGN+E +  +  +                                    QP++SA+RE+SFGH I ++ N T+A ++WHRNQD Y  K DS
Sbjct:  131 LEFNTKYYYVVGIGHTP---RKFWFVTPPKVGPDV-PYTFGLIGDLGQSYDSNMTLTHYELNPAKGKTVLFVGDLSYADNY------------------PNHDNV--RWDTWGRFTERSTAYQPWIWTAGNHEIDFVPEIGEFIPFKPYSHRYHVPYRASDSTAPFWYSIKRASAYIIVLASYSAYGKYTPQYKWLEKELPKVNRSETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQYKVDVVFAGHVHAYERSERVSNIAYNVINGICTPVNDQSAPVYITIGDGGNLEGLATNMTE-----------------------------------PQPKYSAYREASFGHAIFDIKNRTHAHYSWHRNQDGYAVKADS 453          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPS--MILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSG-ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTL-----------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY--KEDS 1584
            L+  TKYYY  G    P   ++    T P+ G +  P    ++GDLG + +++ T+ H   N      +L VGDL YA++Y                          RWD WGRF E  T+  P +   GNHEI+  P++   I F+ Y  R+ VP     S + F+YS      + I+L +Y  Y     Q+ WL+ +L +V+R+ TPWL+   H PWYNSY+ HY E E MR   E    QY VD+VF+GHVHAYER  RV N              D   P+YIT+GDGGN+E +  +  +                                    QP++SA+RE+SFGH I +  N T+A ++WHRNQD Y  K DS
Sbjct:   85 LEFNTKYYYVVGIGHTP---RKFWFVTPPKVGPDV-PYTFGLIGDLGQSYDSNMTLTHYELNPAKGKTVLFVGDLSYADRYPNYDNV--------------------RWDTWGRFTERSTAYQPWIWTAGNHEIDFAPEIGEFIPFKPYSHRYHVPYRASDSTAPFWYSIKRASAYIIVLSSYSAYGKYTPQFMWLEKELPKVNRSETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQYKVDVVFAGHVHAYERSERVSNIAYNVINGICTPVNDQSAPVYITIGDGGNLEGLATNMTE-----------------------------------PQPKYSAYREASFGHAIFDTKNRTHAQYSWHRNQDGYAVKADS 407          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYN--YTL---------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            GL+  TKYYYK G  +    SQE   +T PE   +  P    ++GDLG T N+ +T++H + ++   +L +GDL YA++Y+             + D  +R      WD WGRF+E   +  P +   GNHEIE  P +  +  F+SYL RF  P     S S  +Y+      H I+L +Y  +     Q+ WL ++  RV+R  TPWL+   H P YNS  +H+ E E MR   E+      VDIVF+GHVHAYER  R+ N  Y++         D   P+YITVGDGGN E +   F D                                    QP++SAFRE+S+GH  LE+ N T+A + W+RN D
Sbjct:  108 GLEFDTKYYYKIGSGN---SSQEFWFQTPPEIDPDA-PYIFGIIGDLGQTYNSLSTLEHYMHSEGQTVLFLGDLSYADRYQ-------------YNDVGVR------WDTWGRFVEQSAAYQPWIWSAGNHEIEYMPYMGEVLPFKSYLYRFPTPYAASKSSSPLWYAIRRASAHIIVLSSYSPFVTYTPQWLWLAEEFKRVNREKTPWLIVLMHVPIYNSNEAHFMEGESMRAAFESWFILNKVDIVFAGHVHAYERSYRISNIHYSVSSGDPYPVPDESAPVYITVGDGGNQEGLAGRFRDP-----------------------------------QPDYSAFREASYGHSTLEIKNRTHAFYRWNRNSD 422          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGD 1386
            GL+P T+YYY+CGDSS+PAMS+E + ETLP P  + YP RIA VGDLGLTSNT+TTIDHL++NDPS++++VGDL YANQYRT GGKG  CFSC+FPDAPIRETYQPRWD WGRFMEPLTS+VP MVIEGNHEIEPQ SGITF+SY  RFAVP+ E GS SN YYSFDAGGVHF+MLGAY+DYN TG QYAWLK+DL +VDR VTPWLVA  HPPWYNSYSSHYQEFECMRQEME LLYQY VDIVF+GHVHAYERMNR+YNYTLDPCGP+YIT+GDGGNIE+VDVDFADDPGKC S+ D
Sbjct:  149 GLEPETRYYYRCGDSSVPAMSEEISFETLPLPSKDAYPHRIAFVGDLGLTSNTTTTIDHLMENDPSLVIIVGDLTYANQYRTIGGKGVPCFSCSFPDAPIRETYQPRWDAWGRFMEPLTSKVPTMVIEGNHEIEPQASGITFKSYSERFAVPASESGSNSNLYYSFDAGGVHFVMLGAYVDYNNTGLQYAWLKEDLSKVDRAVTPWLVATMHPPWYNSYSSHYQEFECMRQEMEELLYQYRVDIVFAGHVHAYERMNRIYNYTLDPCGPVYITIGDGGNIEKVDVDFADDPGKCHSSYD 447          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPS-AGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            GLKP T YYY+CGD S  AMS+ H   T+P    ++YP RIAVVGDLGLT NT+ TI HLI N P +IL++GD+ YAN Y  T G  + C+SC+FP+ PI ETYQPRWD WGRFME LTS+VP+MVIEGNHEIE Q    TFE+Y +RFA P  E GS S  YYSF+AGG+HF+MLGAYI Y+ +  QY WLK DL +VDR+VTPWLVA+WHPPWY+SY++HY+E ECM++ ME LLY YG DIVF+GHVHAYER NRVYNY LDPCGP+YI +GDGGN E++ ++ ADDPGKCP       P  GG C  NF+       FCW +QP++SA RESSFGHGILE+ N T+ALWTW+RNQD+  E   GDQ+YIVRQP+ C    ++++
Sbjct:  149 GLKPSTIYYYRCGDPSRRAMSKIHHFRTMPVSSPSSYPGRIAVVGDLGLTYNTTDTISHLIHNSPDLILLIGDVSYANLY-LTNGTSSDCYSCSFPETPIHETYQPRWDYWGRFMENLTSKVPLMVIEGNHEIELQAENKTFEAYSSRFAFPFNESGSSSTLYYSFNAGGIHFVMLGAYIAYDKSAEQYEWLKKDLAKVDRSVTPWLVASWHPPWYSSYTAHYREAECMKEAMEELLYSYGTDIVFNGHVHAYERSNRVYNYELDPCGPVYIVIGDGGNREKMAIEHADDPGKCPEPLTTPDPVMGGFCAWNFT---PSDKFCWDRQPDYSALRESSFGHGILEMKNETWALWTWYRNQDSSSE--VGDQIYIVRQPDRCPLHHRLVN 530          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCS 1629
            GLKP T Y Y+CGD S+ AMS+E+   T+P+     YP RI V GDLGLT NTST + H++ N P +++++G   YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS E GS S  YYSF+AGG HFI+L +Y  Y+ +  QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNYTLD CGP+YIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV N T+ALW+W+RNQD Y      D ++IVRQPE+CS
Sbjct:  158 GLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESGSFSPLYYSFNAGGAHFIVLNSYTLYDNSSDQYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEVKNETHALWSWNRNQDLYY--LAADVIHIVRQPEMCS 542          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1569
            L+  T YYY+CG +       E + +T P    +T+P   A+VGDLG T  T+ T+ H+   D  + L+ GDL YA                        +T+QP WD +GR +EPL S+ P MV EGNHEIE  P +   TF+SY  R+ +P  E  S SN YYSFD  GVH +MLG+Y D++    QY WL+ DL +VDR  TPW+V   H PWYN+  +H  E E MR+ ME+LL+   VD+VFSGHVHAYER  RVYN   DPCGP++IT+GDGGN E + + F   P                                      S FRESSFGHG L+V++   A W+WHRN D+
Sbjct:  113 LQANTTYYYRCGGNG-----PEFSFKTPP----STFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYA------------------------DTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPL-----------------------------------SEFRESSFGHGRLKVMDGKRAHWSWHRNNDS 405          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGIT-FESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYI 1605
            L+  T YYY+CG         E  L+T P      +P   AV GDLG T  T +T+DH+ Q   ++ L+ GDL YA+                          Q +WD +G  ++PL S  P MV +GNHE E     +  F S+ +R+ +P EE GS SN YYSF+  GVH IMLG+Y DY+    QY+WLK DL +VDR  TPWL+  +H PWYNS ++H  E + M  EME LLY  GVDIVF+GHVHAYER  RV N   DPCGP++IT+GDGGN E +   + D     PS                              PEWS FRE+SFGHG L++VNST+ALWTWHRN D   E +  D+V++
Sbjct:  113 LEADTVYYYRCGGEG-----PEFHLKTPPAQ----FPITFAVAGDLGQTGWTKSTLDHIDQCKYAVHLLPGDLSYADYM------------------------QHKWDTFGELVQPLASVRPWMVTQGNHEKESIPFIVDEFVSFNSRWKMPYEESGSNSNLYYSFEVAGVHAIMLGSYTDYDRYSDQYSWLKADLSKVDRERTPWLIVLFHVPWYNSNNAHQHEGDEMMAEMEPLLYASGVDIVFTGHVHAYERTKRVNNGKSDPCGPVHITIGDGGNREGLARKYKD-----PS------------------------------PEWSVFREASFGHGELQMVNSTHALWTWHRNDD--DEPTRSDEVWL 414          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFEC--MRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            LKP T YYYKCG    P+ +QE +  T P    + +P + AV GDLG +  + +T++H+ + D  + ++ GDL YAN Y                        QP WD +GR ++PL S+ P MV  GNHE+E  P +    F +Y  R+ +P EE GS SN YYSF+  GVH IMLG+Y D+     QY WL+++L ++DR  TPW+VA  H PWYNS  +H  E E   M++ ME LLY+  VD+VF+GHVHAYER +RVY    D CGP+YI +GDGGN+E +   + D                                     PE S FRE+SFGHG L V N+T+A W WHRN D
Sbjct:  110 LKPNTVYYYKCGG---PSSTQEFSFRTPP----SKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMY------------------------QPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYERFSRVYQDKFDKCGPVYINIGDGGNLEGLATKYRD-----------------------------------PNPEISLFREASFGHGQLVVENATHARWEWHRNDD 405          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            LKP TKYYY+CG         E + +T P    + +P   AV GDLG T  T  T+D + + D  + L+ GDL YA                        +T+QP WD +GR +E L S  P MV EGNHEIE  P    I+F+SY  R+ +P  E  S SN YYSFD  GVH +MLG+Y  Y +   QY WL+ DL +VDR  TPWLV   H PWY++  +HY E E MR  +E+LLY+  VD+VF+GHVH YER   +YN   DPCGP+YIT+GDGGN E + + F                                      Q   S FRESSFGHG L +++   A W+WHRN D
Sbjct:  117 LKPNTKYYYRCGGHG-----DEFSFKTPP----SKFPIEFAVAGDLGQTDWTVRTLDQIRKRDFDVFLLPGDLSYA------------------------DTHQPLWDSFGRLLETLASTRPWMVTEGNHEIESFPTNDHISFKSYNARWLMPHAESLSHSNLYYSFDVAGVHTVMLGSYTPYESHSDQYHWLQADLRKVDRKKTPWLVVVMHTPWYSTNKAHYGEGEKMRSALESLLYRAQVDVVFAGHVHTYERFKPIYNKKADPCGPMYITIGDGGNREGLALRFK-----------------------------------KPQSPLSEFRESSFGHGRLRIIDHKRAHWSWHRNND 408          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQND--PSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTL-----------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY 1572
            L+  TKYYY+ G   I   ++     T PE G +  P    ++GDLG + +++ T+ H  +N      +L VGDL YA+ Y                  P  +    RWD WGRF+E  T+  P +   GNHEI+  P++     F+ +  R+ VP +  GS   F+Y       + I+L +Y  Y     QY WL+++L +V+RT TPWL+   H PWYNSY+ HY E E MR   E    Q+ VD+VF+GHVHAYER  RV N              D   P+YIT+GDGGN+E +  +  D                                    QPE+SAFRE+SFGH  L++ N T+A ++WHRNQD Y
Sbjct:  124 LEYNTKYYYEVG---IGNTTRSFWFTTPPEVGPDV-PYTFGLIGDLGQSFDSNRTLTHYERNPIKGQAVLFVGDLSYADNY------------------PNHDNV--RWDTWGRFVERSTAYQPWIWTAGNHEIDFAPEIGETKPFKPFTKRYHVPYKASGSTETFWYPIKRASAYIIVLSSYSAYGKYTPQYKWLEEELPKVNRTETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQHKVDLVFAGHVHAYERSERVSNVAYDIVNGKCTPVRDQSAPVYITIGDGGNLEGLATNMTD-----------------------------------PQPEYSAFREASFGHATLDIKNRTHAYYSWHRNQDGY 440          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSM---ILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVS-GITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTL-----------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVY 1602
            L+  TKYYY  G   +    ++    T PE G +  P    ++GDLG + +++ T+ H  +N+P+    +L VGD+ YA+ Y               PD   R     RWD WGRF E  T+  P +   GNHE++  P++     F+ +  R+  P    GS   F+YS   G  + I+L +Y  Y     QY WL+++  +V+RT TPWL+   H PWYNSY  HY E E MR   EA   +Y VD+VF+GHVHAYER  RV N              D   P+YIT+GDGGNIE +     +                                    QP++SAFRE+SFGH I  + N T+A + WHRN D Y  +  GD+++
Sbjct:  127 LEYDTKYYYVLG---VGQTERKFWFFTPPEIGPDV-PYTFGLIGDLGQSYDSNITLTHY-ENNPTKGQAVLFVGDISYADTY---------------PDHDNR-----RWDSWGRFAERSTAYQPWIWTTGNHELDFAPEIGENRPFKPFTHRYRTPYRSSGSTEPFWYSIKRGPAYIIVLASYSAYGKYTPQYQWLEEEFPKVNRTETPWLIVLMHSPWYNSYDYHYMEGETMRVMYEAWFVKYKVDVVFAGHVHAYERSERVSNIAYNVVNGICTPVKDQSAPVYITIGDGGNIEGLATKMTE-----------------------------------PQPKYSAFREASFGHAIFSIKNRTHAHYGWHRNHDGYAVE--GDRMW 451          

Query:  490 GLKPGTKYYYKCG-DSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSM-ILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGI-TFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRV----YNYT-------LDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            GL+  TKY Y+ G D S+    ++ +  T P+ G +  P    ++GDLG T  ++ T+ H + N     +L  GDL YA+                  D P  +  Q +WD WGRFMEP  +  P +   GNHEI+  P +     F+ Y  R+    +   S S  +YS      H I+L +Y  Y     QY WL+ +L  V+R  TPWL+   H PWYNS + HY E E MR   E+ L    VD+V SGHVHAYER  R+    YN T        DP  P+YIT+GDGGNIE +   F D                                    QP +SA+RE+SFGH +LE++N T+A +TWHRNQD
Sbjct:  123 GLEYDTKYIYEVGTDKSV----RQFSFTTPPKIGPDV-PYTFGIIGDLGQTYASNETLYHYMSNPKGQAVLFAGDLSYAD------------------DHPNHD--QRKWDTWGRFMEPCAAYQPFIFAAGNHEIDFVPNIGEPHAFKPYTHRYPNAYKASQSTSPLWYSVRRASAHIIVLSSYSAYGKYTPQYIWLEQELKNVNREETPWLIVIVHSPWYNSNNYHYMEGESMRVMFESWLVNSKVDLVLSGHVHAYERSERISNIKYNITNGLSSPVKDPNAPIYITIGDGGNIEGIANSFVD-----------------------------------PQPSYSAYREASFGHAVLEIMNRTHAQYTWHRNQD 437          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            L+PGTKYYYKCGDSS PAMS+E+  ETLP PG   YPRRIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYN TGAQYAWLK DLH+VDR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLD CGP+YITVGDGGNIE+V+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQ+YIVRQP LCS ++KV++
Sbjct:  140 LEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQPHLCSTASKVVA 525          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+PGTKY+YKCGDSSIPAMS+EH  ETLP P  N YP RIA++GDLGLTSN+STTIDH+I NDPSMILMVGDL YANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITF+SYLTR+AVPSEE GS SNFYYSFDAGG+HF+MLGAY+DYN+TGAQY+WLK DL++VDR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNYTLDPCGP+YITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQ+Y+VRQPELC
Sbjct:  127 GLEPGTKYFYKCGDSSIPAMSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPELC 505          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPE 1620
            GL+PGT+YYYKCGDSSIPAMSQEH  ET P+P  N YP RIAV+GDLGLTSN+++TIDHL  NDPSMILMVGDL YANQY TTGGKGASC+SCAFPDAPIRETYQPRWDGWGRFMEPLTS +PMMVIEGNHEIEPQ  GITF+SYLTRFAVP+EE GSKSNFYYSFDAGG+HFIMLGAY+DYN+TGAQ+AWLK DL  VDR+VTPWLVAAWH PWYNSY+SHYQEFECMR EME LL++Y VDIVF GHVHAYERMNRV+NYTLDPCGP+YITVGDGGNIE+VDVD ADDPGKCPSAGDN PEFGGVC  NFS+GPAKGNFCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YKE++ GDQ+YIVRQPE
Sbjct:  134 GLEPGTRYYYKCGDSSIPAMSQEHYFETFPKPSPNNYPARIAVIGDLGLTSNSTSTIDHLNYNDPSMILMVGDLTYANQYLTTGGKGASCYSCAFPDAPIRETYQPRWDGWGRFMEPLTSEIPMMVIEGNHEIEPQAGGITFKSYLTRFAVPAEESGSKSNFYYSFDAGGIHFIMLGAYVDYNSTGAQFAWLKKDLQSVDRSVTPWLVAAWHSPWYNSYASHYQEFECMRLEMEELLFRYRVDIVFDGHVHAYERMNRVFNYTLDPCGPVYITVGDGGNIEKVDVDHADDPGKCPSAGDNIPEFGGVCKSNFSTGPAKGNFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDNYKENAVGDQIYIVRQPE 510          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWG-----------------------------------RFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKV 1644
            GL+PGT+YYYKCGDSSIPAMSQE+  ET  +P    YP RIAV+GDLGLTSN+STT+DHL  NDPSMILM+GDL YANQY TTGGKGASCFSCAFPDAPIRETYQPRWDGWG                                   RFM+PLTS+VPMMVIEGNHEIEPQ  GITF+SYLTRFAVP+EE GSKSNF+YSFD GG+HFIMLGAY+DYN TGAQ+ WLK DL  VDR+VTPWLVA  HPPWYNSY+SHYQEFECMR EMEALLYQY VDI+F+GHVHAYERMNRVYNYTLDPCGP+YITVGDGGNIE+VDVD AD+PGKCPS+GDN PEFGGVCH NF+ GPAKGNFCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD+YKE++ GDQ+YIVRQPELC + +K+
Sbjct:  155 GLEPGTRYYYKCGDSSIPAMSQENYFETFAKPSPKNYPARIAVIGDLGLTSNSSTTVDHLSYNDPSMILMIGDLTYANQYLTTGGKGASCFSCAFPDAPIRETYQPRWDGWGSNCFPKLSTSVTSAYASRISSKDRWYDLLIRCLTIRFMQPLTSKVPMMVIEGNHEIEPQADGITFKSYLTRFAVPAEESGSKSNFFYSFDTGGIHFIMLGAYVDYNKTGAQFDWLKKDLQNVDRSVTPWLVATMHPPWYNSYASHYQEFECMRLEMEALLYQYRVDIIFNGHVHAYERMNRVYNYTLDPCGPIYITVGDGGNIEKVDVDHADEPGKCPSSGDNIPEFGGVCHSNFTFGPAKGNFCWKKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDSYKENAVGDQIYIVRQPELCFKDSKL 574          

Query:  490 GLKPGTKYYYKCGDSSIPA-MSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL P T+YYY+CGDSS+ A +S+E +  TLP P    YPRR+AVVGDLGLT N+++T+DHL +NDPS++LMVGD+ YANQYRTTGG+G  CFSC+FPDAPIRE+YQPRWDGW RFMEPL SR+PMMVIEGNHEIEPQ  G  +TF SY  RFAVP+EE GS S FYYSFDAGG+HFIMLGAY+DYN TGAQY+WLK DL RVDR VTPW+VA+WH PWYNSYSSHYQEFECMRQEME LLYQ+ VDIVFSGHVHAYERMNRV+NYTLDPCGP+YI +GDGGNIE++D+D ADDPGKCPS GDN PEFGG+CHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY EDS GDQ+YIVRQP+ C
Sbjct:  176 GLAPSTRYYYRCGDSSLKAGLSEERSFTTLPAPAPGAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSLVLMVGDMTYANQYRTTGGRGVPCFSCSFPDAPIRESYQPRWDGWARFMEPLASRIPMMVIEGNHEIEPQGHGGAVTFASYSARFAVPAEESGSNSKFYYSFDAGGIHFIMLGAYVDYNRTGAQYSWLKKDLQRVDRAVTPWVVASWHSPWYNSYSSHYQEFECMRQEMEGLLYQHRVDIVFSGHVHAYERMNRVFNYTLDPCGPVYIIIGDGGNIEKIDIDHADDPGKCPSPGDNHPEFGGLCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEDSVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSIPA-MSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL P T+YYY+CGDSS+ A +S+E +  TLP P    YPRR+AVVGDLGLT N+++T+DHL +NDPS++LMVGD+ YANQYRTTGG+G  CFSC+FPDAPIRE+YQPRWDGW RFMEPL SR+PMMVIEGNHEIEPQ  G  +TF SY  RFAVP+EE GS S FYYSFDAGG+HFIMLGAY+DYN TGAQY+WLK DL RVDR VTPW+VA+WH PWYNSYSSHYQEFECMRQEME LLYQ+ VDIVFSGHVHAYERMNRV+NYTLDPCGP+YI +GDGGNIE++D+D ADDPGKCPS GDN PEFGG+CHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY EDS GDQ+YIVRQP+ C
Sbjct:  176 GLAPSTRYYYRCGDSSLKAGLSEERSFTTLPAPAPGAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSLVLMVGDMTYANQYRTTGGRGVPCFSCSFPDAPIRESYQPRWDGWARFMEPLASRIPMMVIEGNHEIEPQGHGGAVTFASYSARFAVPAEESGSNSKFYYSFDAGGIHFIMLGAYVDYNRTGAQYSWLKKDLQRVDRAVTPWVVASWHSPWYNSYSSHYQEFECMRQEMEGLLYQHRVDIVFSGHVHAYERMNRVFNYTLDPCGPVYIIIGDGGNIEKIDIDHADDPGKCPSPGDNHPEFGGLCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEDSVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSI---PAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+     +S E + ETLP      YPRR+AVVGDLGLT N+++T++HL +NDPS++++VGD+ YANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNHEIEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL ++DR VTPW+VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLDPCGP+YIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQ+YIVRQP+ C
Sbjct:  174 GLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHEIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWVVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSI---PAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+     +S E + ETLP      YPRR+AVVGDLGLT N+++T++HL +NDPS++++VGD+ YANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNHEIEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL ++DR VTPW+VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLDPCGP+YIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQ+YIVRQP+ C
Sbjct:  174 GLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHEIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWVVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSI---PAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+     +S E + ETLP      YPRR+AVVGDLGLT N+++T++HL +NDPS++++VGD+ YANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNH+IEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL ++DR VTPW VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLDPCGP+YIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQ+YIVRQP+ C
Sbjct:  174 GLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHDIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWAVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSIPA-MSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GL+P T+YYY+CGDSS+   +S E +  TLP P  + YPRR+AVVGDLGLT N+++T+DHL +NDPSMILMVGD+ YANQY TTGG+G  CFSC+FPDAPIRE+YQPRWDGWGRFMEPLTS+VPMMV EGNHEIEPQ  G  +TF SYL RFAVPSEE GS + FYYSF+AGG+HFIMLGAY+DYN TGAQY+WL+ DL +VDR VTPW+VA+WH PWYNS SSHYQEFECMRQEME LLYQ+GVDIVFSGHVHAYERMNRV+NYTLD CGP+YIT+GDGGNIE++D D ADDPG CPS GDN PEFGGVCHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY E S GD++YIVR+P+ C
Sbjct:  174 GLRPSTRYYYRCGDSSLKGGLSDERSFRTLPAPAPDAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSMILMVGDMTYANQYLTTGGRGVPCFSCSFPDAPIRESYQPRWDGWGRFMEPLTSKVPMMVTEGNHEIEPQGHGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLQKVDRRVTPWVVASWHSPWYNSCSSHYQEFECMRQEMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDSCGPVYITIGDGGNIEKIDTDHADDPGSCPSPGDNQPEFGGVCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEHSVGDEIYIVREPDKC 555          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGD 1386
            GL+P T+YYY+CGDSS+PAMS+E + ETLP P  + YP RIA VGDLGLTSNT+TTIDHL++NDPS++++VGDL YANQYRT GGKG  CFSC+FPDAPIRETYQPRWD WGRFMEPLTS+VP MVIEGNHEIEPQ SGITF+SY  RFAVP+ E GS SNFYYSFDAGGVHF+MLGAY+DYN TG QYAWLK+DL +VDR VTPWLVA  HPPWYNSYSSHYQEFECMRQEME LLYQY VDIVF+GHVHAYERMNR+YNYTLDPCGP+YIT+GDGGNIE+VDVDFADDPGKC S+ D
Sbjct:  149 GLEPETRYYYRCGDSSVPAMSEEISFETLPLPSKDAYPHRIAFVGDLGLTSNTTTTIDHLMENDPSLVIIVGDLTYANQYRTIGGKGVPCFSCSFPDAPIRETYQPRWDAWGRFMEPLTSKVPTMVIEGNHEIEPQASGITFKSYSERFAVPASESGSNSNFYYSFDAGGVHFVMLGAYVDYNNTGLQYAWLKEDLSKVDRAVTPWLVATMHPPWYNSYSSHYQEFECMRQEMEELLYQYRVDIVFAGHVHAYERMNRIYNYTLDPCGPVYITIGDGGNIEKVDVDFADDPGKCHSSYD 447          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPS-AGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            GLKP T YYY+CGD S  AMS+ H   T+P    ++YP RIAVVGDLGLT NT+ TI HLI N P +IL++GD+ YAN Y  T G  + C+SC+FP+ PI ETYQPRWD WGRFME LTS+VP+MVIEGNHEIE Q    TFE+Y +RFA P  E GS S  YYSF+AGG+HF+MLGAYI Y+ +  QY WLK DL +VDR+VTPWLVA+WHPPWY+SY++HY+E ECM++ ME LLY YG DIVF+GHVHAYER NRVYNY LDPCGP+YI +GDGGN E++ ++ ADDPGKCP       P  GG C  NF+       FCW +QP++SA RESSFGHGILE+ N T+ALWTW+RNQD+  E   GDQ+YIVRQP+ C    ++++
Sbjct:  149 GLKPSTIYYYRCGDPSRRAMSKIHHFRTMPVSSPSSYPGRIAVVGDLGLTYNTTDTISHLIHNSPDLILLIGDVSYANLY-LTNGTSSDCYSCSFPETPIHETYQPRWDYWGRFMENLTSKVPLMVIEGNHEIELQAENKTFEAYSSRFAFPFNESGSSSTLYYSFNAGGIHFVMLGAYIAYDKSAEQYEWLKKDLAKVDRSVTPWLVASWHPPWYSSYTAHYREAECMKEAMEELLYSYGTDIVFNGHVHAYERSNRVYNYELDPCGPVYIVIGDGGNREKMAIEHADDPGKCPEPLTTPDPVMGGFCAWNFT---PSDKFCWDRQPDYSALRESSFGHGILEMKNETWALWTWYRNQDSSSE--VGDQIYIVRQPDRCPLHHRLVN 530          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCS 1629
            GLKP T Y Y+CGD S+ AMS+E+   T+P+     YP RI V GDLGLT NTST + H++ N P +++++G   YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS E GS S  YYSF+AGG HFI+L +Y  Y+ +  QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNYTLD CGP+YIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV N T+ALW+W+RNQD Y      D ++IVRQPE+CS
Sbjct:  158 GLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESGSFSPLYYSFNAGGAHFIVLNSYTLYDNSSDQYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEVKNETHALWSWNRNQDLYY--LAADVIHIVRQPEMCS 542          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEV 1521
            GLKP T Y Y+CGD S+ AMS+E+   T+P+     YP RI V GDLGLT NTST + H++ N P +++++G   YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS E GS S  YYSF+AGG HFI+L +Y  Y+ +  QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNYTLD CGP+YIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV
Sbjct:   77 GLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESGSFSPLYYSFNAGGAHFIVLNSYTLYDNSSDQYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEV 427          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCS 1629
            GLKP T Y Y+CGD S+ AMS+E+   T+P+     YP RI V GDLGLT NTST + H++ N P +++++G   YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS E                                QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNYTLD CGP+YIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV N T+ALW+W+RNQD Y      D ++IVRQPE+CS
Sbjct:  158 GLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESAD-----------------------------QYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEVKNETHALWSWNRNQDLYY--LAADVIHIVRQPEMCS 513          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1569
            L+  T YYY+CG +       E + +T P    +T+P   A+VGDLG T  T+ T+ H+   D  + L+ GDL YA                        +T+QP WD +GR +EPL S+ P MV EGNHEIE  P +   TF+SY  R+ +P  E  S SN YYSFD  GVH +MLG+Y D++    QY WL+ DL +VDR  TPW+V   H PWYN+  +H  E E MR+ ME+LL+   VD+VFSGHVHAYER  RVYN   DPCGP++IT+GDGGN E + + F   P                                      S FRESSFGHG L+V++   A W+WHRN D+
Sbjct:  113 LQANTTYYYRCGGNG-----PEFSFKTPP----STFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYA------------------------DTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPL-----------------------------------SEFRESSFGHGRLKVMDGKRAHWSWHRNNDS 405          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGIT-FESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYI 1605
            L+  T YYY+CG         E  L+T P      +P   AV GDLG T  T +T+DH+ Q   ++ L+ GDL YA+                          Q +WD +G  ++PL S  P MV +GNHE E     +  F S+ +R+ +P EE GS SN YYSF+  GVH IMLG+Y DY+    QY+WLK DL +VDR  TPWL+  +H PWYNS ++H  E + M  EME LLY  GVDIVF+GHVHAYER  RV N   DPCGP++IT+GDGGN E +   + D     PS                              PEWS FRE+SFGHG L++VNST+ALWTWHRN D   E +  D+V++
Sbjct:  113 LEADTVYYYRCGGEG-----PEFHLKTPPAQ----FPITFAVAGDLGQTGWTKSTLDHIDQCKYAVHLLPGDLSYADYM------------------------QHKWDTFGELVQPLASVRPWMVTQGNHEKESIPFIVDEFVSFNSRWKMPYEESGSNSNLYYSFEVAGVHAIMLGSYTDYDRYSDQYSWLKADLSKVDRERTPWLIVLFHVPWYNSNNAHQHEGDEMMAEMEPLLYASGVDIVFTGHVHAYERTKRVNNGKSDPCGPVHITIGDGGNREGLARKYKD-----PS------------------------------PEWSVFREASFGHGELQMVNSTHALWTWHRNDD--DEPTRSDEVWL 414          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFEC--MRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            LKP T YYYKCG    P+ +QE +  T P    + +P + AV GDLG +  + +T++H+ + D  + ++ GDL YAN Y                        QP WD +GR ++PL S+ P MV  GNHE+E  P +    F +Y  R+ +P EE GS SN YYSF+  GVH IMLG+Y D+     QY WL+++L ++DR  TPW+VA  H PWYNS  +H  E E   M++ ME LLY+  VD+VF+GHVHAYER +RVY    D CGP+YI +GDGGN+E +   + D                                     PE S FRE+SFGHG L V N+T+A W WHRN D
Sbjct:  110 LKPNTVYYYKCGG---PSSTQEFSFRTPP----SKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMY------------------------QPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYERFSRVYQDKFDKCGPVYINIGDGGNLEGLATKYRD-----------------------------------PNPEISLFREASFGHGQLVVENATHARWEWHRNDD 405          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            LKP TKYYY+CG         E + +T P    + +P   AV GDLG T  T  T+D + + D  + L+ GDL YA                        +T+QP WD +GR +E L S  P MV EGNHEIE  P    I+F+SY  R+ +P  E  S SN YYSFD  GVH +MLG+Y  Y +   QY WL+ DL +VDR  TPWLV   H PWY++  +HY E E MR  +E+LLY+  VD+VF+GHVH YER   +YN   DPCGP+YIT+GDGGN E + + F                                      Q   S FRESSFGHG L +++   A W+WHRN D
Sbjct:  117 LKPNTKYYYRCGGHG-----DEFSFKTPP----SKFPIEFAVAGDLGQTDWTVRTLDQIRKRDFDVFLLPGDLSYA------------------------DTHQPLWDSFGRLLETLASTRPWMVTEGNHEIESFPTNDHISFKSYNARWLMPHAESLSHSNLYYSFDVAGVHTVMLGSYTPYESHSDQYHWLQADLRKVDRKKTPWLVVVMHTPWYSTNKAHYGEGEKMRSALESLLYRAQVDVVFAGHVHTYERFKPIYNKKADPCGPMYITIGDGGNREGLALRFK-----------------------------------KPQSPLSEFRESSFGHGRLRIIDHKRAHWSWHRNND 408          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSM---ILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVS-GITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTL-----------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVY 1602
            L+  TKYYY  G   +    ++    T PE G +  P    ++GDLG + +++ T+ H  +N+P+    +L VGD+ YA+ Y               PD   R     RWD WGRF E  T+  P +   GNHE++  P++     F+ +  R+  P    GS   F+YS   G  + I+L +Y  Y     QY WL+++  +V+RT TPWL+   H PWYNSY  HY E E MR   EA   +Y VD+VF+GHVHAYER  RV N              D   P+YIT+GDGGNIE +     +                                    QP++SAFRE+SFGH I  + N T+A + WHRN D Y  +  GD+++
Sbjct:  127 LEYDTKYYYVLG---VGQTERKFWFFTPPEIGPDV-PYTFGLIGDLGQSYDSNITLTHY-ENNPTKGQAVLFVGDISYADTY---------------PDHDNR-----RWDSWGRFAERSTAYQPWIWTTGNHELDFAPEIGENRPFKPFTHRYRTPYRSSGSTEPFWYSIKRGPAYIIVLASYSAYGKYTPQYQWLEEEFPKVNRTETPWLIVLMHSPWYNSYDYHYMEGETMRVMYEAWFVKYKVDVVFAGHVHAYERSERVSNIAYNVVNGICTPVKDQSAPVYITIGDGGNIEGLATKMTE-----------------------------------PQPKYSAFREASFGHAIFSIKNRTHAHYGWHRNHDGYAVE--GDRMW 451          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRS 1635
            GL+P TKY+YKCGDSSIPAMS+EH  ETLP P  N YP RIA++GDLGLTSN+STTIDH+I NDPSMILMVGDL YANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITF+SYLTR+AVPSEE GS SNFYYSFDAGG+HF+MLGAY+DYN+TGAQY+WLK DL++VDR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNYTLDPCGP+YITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQ+Y+VRQPELC  S
Sbjct:  155 GLEPETKYFYKCGDSSIPAMSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPELCIAS 536          

Query:  547 MSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRS 1635
            MS+EH  ETLP P  N YP RIA++GDLGLTSN+STTIDH+I NDPSMILMVGDL YANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITF+SYLTR+AVPSEE GS SNFYYSFDAGG+HF+MLGAY+DYN+TGAQY+WLK DL++VDR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNYTLDPCGP+YITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQ+Y+VRQPELC  S
Sbjct:    1 MSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPELCIAS 363          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEF-GGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKV 1644
            GLKP T Y+Y+CGD SIPAMS ++  +T+P  G  +YP RIA+VGDLGLT NT++T+DH+I N+P +IL+VGD+CYAN Y  T G GA C+SC+F   PI ETYQPRWD WGR+M+P+TS++P+MV+EGNHEIE QV   TF +Y +RFA PS+E GS S FYYSF+AGG+HFIMLG YI YN +  QY WLK DL +VDR VTPWLVA WHPPWY++Y +HY+E ECMR  ME LLYQYGVDI+F+GH+HAYER NRVYNYTLDPCGP++ITVGDGGN E++ +  AD+P  CP       E+ GG C  NF+SGPA G FCW +QP++SA+RESSFGHGI EV N T+ALWTWHRNQD Y  +S GDQ+YIVRQPE C    K+
Sbjct:  155 GLKPNTLYHYQCGDPSIPAMSSKYYFKTMPASGPKSYPSRIAIVGDLGLTYNTTSTVDHVIGNNPDLILLVGDVCYANLY-LTNGTGADCYSCSFSQTPIHETYQPRWDYWGRYMQPVTSKIPIMVVEGNHEIEKQVENQTFVAYSSRFAFPSKESGSSSTFYYSFNAGGIHFIMLGGYIAYNKSAHQYKWLKKDLAKVDRKVTPWLVATWHPPWYSTYKAHYREAECMRTAMEDLLYQYGVDIIFNGHIHAYERSNRVYNYTLDPCGPVHITVGDGGNREKMAIAHADEPRNCPDPSTTPDEYMGGFCAFNFTSGPAAGKFCWDRQPDYSAYRESSFGHGIFEVKNETHALWTWHRNQDMY--NSPGDQIYIVRQPERCPTEPKM 537          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPE--FGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GLKP   YYY+CGD SI A+S  ++ +T+P     TYP+RIAV+GDLGLT NTSTTI H+I N P + L+VGD+ YAN Y  T G G  C+SC+FP++PI ETYQPRWD WGRFM+PL S+VP+MV+EGNHEIE QV   TF +Y +RFA P++E GS S FYYSF+AGG+HF+MLGAYI Y+ +  QY WL+ DL  VDR VTPWLVA WHPPWY+SY++HY+E ECM   ME LLY Y VDIVF+GHVHAYER NRVYNYTLDPCGP++I VGDGGN E++ V  AD+PG CP     TP+   GG C LNF++GPA G FCW +QP++SAFRESSFGHGILEV N T+ALWTWHRNQD+    + GDQ+YIVRQP+ C
Sbjct:  165 GLKPDKLYYYRCGDPSIGALSDVYSFKTMPVSSPKTYPKRIAVMGDLGLTYNTSTTISHVISNKPQLALLVGDVTYANLY-LTNGTGCDCYSCSFPNSPIHETYQPRWDYWGRFMQPLVSKVPLMVVEGNHEIEKQVGNQTFAAYSSRFAFPAKESGSSSTFYYSFNAGGIHFVMLGAYIAYHRSSDQYRWLERDLANVDRFVTPWLVAVWHPPWYSSYNAHYREAECMMAAMEELLYSYAVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIVVGDGGNREKMAVGHADEPGNCPDPA-TTPDQHIGGFCALNFTTGPAAGQFCWDRQPDYSAFRESSFGHGILEVKNQTWALWTWHRNQDS--RSTVGDQIYIVRQPDKC 541          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPE--FGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GLKP   YYY+CGD SI A+S  ++ +T+P     TYP+RIAV+GDLGLT NTSTTI H+I N P + L+VGD+ YAN Y  T G G  C+SC+FP++PI ETYQPRWD WGRFM+PL S+VP+MV+EGNHEIE QV   TF +Y +RFA P++E GS S FYYSF+AGG+HF+MLGAYI Y+ +  QY WL+ DL  VDR VTPWLVA WHPPWY+SY++HY+E ECM   ME LLY Y VDIVF+GHVHAYER NRVYNYTLDPCGP++I VGDGGN E++ V  AD+PG CP     TP+   GG C LNF++GPA G FCW +QP++SAFRESSFGHGILEV N T+ALWTWHRNQD+    + GDQ+YIVRQP+ C
Sbjct:  181 GLKPDKLYYYRCGDPSIGALSDVYSFKTMPVSSPKTYPKRIAVMGDLGLTYNTSTTISHVISNKPQLALLVGDVTYANLY-LTNGTGCDCYSCSFPNSPIHETYQPRWDYWGRFMQPLVSKVPLMVVEGNHEIEKQVGNQTFAAYSSRFAFPAKESGSSSTFYYSFNAGGIHFVMLGAYIAYHRSSDQYRWLERDLANVDRFVTPWLVAVWHPPWYSSYNAHYREAECMMAAMEELLYSYAVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIVVGDGGNREKMAVGHADEPGNCPDPA-TTPDQHIGGFCALNFTTGPAAGQFCWDRQPDYSAFRESSFGHGILEVKNQTWALWTWHRNQDS--RSTVGDQIYIVRQPDKC 557          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKC--PSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            GL+P T Y Y+CGD  I AMS      T+P      YPRR+AVVGDLGLT NTSTT  HL+ N P ++++VG + YA+ Y  T G G+ C+ C+F ++PI ETYQPRWD WGRFM+PL + VP M++ G HEIEPQ     F SY +RF  PSEE GS S+ YYSF+AGG+HF++L  Y  Y+ +  QY WL+ DL+ V+R VTPWLVA W+PPWY+++ + Y+E ECMR EME LLY++GVDIVF+GHVHAYER NRVYNY+LDPCGP+YIT+GDGG+ E++ V  ADDP +C  PS   +    GG C  NF+SGPA                E        +V N T+ALW+WHRN+D Y  ++ GD +YIVR+P+ C  +  +I+
Sbjct:  154 GLEPSTLYQYQCGDPYISAMSDVFYFRTMPPSSPTNYPRRVAVVGDLGLTYNTSTTFSHLLSNHPDLLVLVGGISYADMY-LTNGTGSDCYPCSFDESPIHETYQPRWDYWGRFMQPLVANVPTMLVGGKHEIEPQAEDQIFVSYSSRFVFPSEESGSSSSVYYSFNAGGIHFVILNPYTYYDKSSDQYKWLEGDLYNVNRNVTPWLVAVWYPPWYSTFKAQYREAECMRVEMEDLLYEHGVDIVFNGHVHAYERSNRVYNYSLDPCGPVYITIGDGGSREDIAVTHADDPDECPEPSTTADLDIGGGFCGFNFTSGPA---------------AEHKLMGCSFQVKNVTHALWSWHRNRDYY--ETAGDILYIVREPDRCLANQALIT 524          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1569
            L+PGT YYY+CG S       E + +T P     T P    V+GDLG T  T++T+ H+   D  ++L+ GDL YA                        +T QP WD +GR +E   S+ P MV EGNHE E  P +    F++Y  R+ +P EE  S SN YYSF+  G H IMLG+Y D++    QY WL+ DL  +DR  TPW++   H PWYN+ ++H  E E MR+ ME LLY+  VD+VF+GHVHAYER  R+Y+  +DPCGP+YIT+GDGGN E + + F                            PA            S +RE+SFGHG L +++ T A W+WHRN D+
Sbjct:   54 LEPGTTYYYRCGGSG-----PELSFKTPPA----TLPLEFVVIGDLGQTGWTNSTLAHVNSRDYDVLLLPGDLSYA------------------------DTNQPLWDSFGRLVEKYASQRPWMVTEGNHETEIFPIIQPHGFKAYNARWLMPYEESNSSSNLYYSFNVVGTHVIMLGSYTDFDEHSQQYKWLEADLGSIDRKKTPWVIVLLHAPWYNTNNAHQGEGESMRKAMEELLYKARVDVVFAGHVHAYERFARIYDNKVDPCGPVYITIGDGGNREGLALTF--------------------------QNPAS---------PLSLYREASFGHGRLRIMDETRAHWSWHRNNDS 346          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEP-QVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYI 1605
            L+  T YYY+CG         E+ L+T P      +P   AV GDLG T  T +T+DH+      + L+ GDL YA+                          Q RWD +G  +EPL S  P MV +GNHE E        F+SY +R+ +P EE GS SN YYSF+  G H IMLG+Y DY+    QY WLK D+ +VDR  TPWL+  +H PWYNS  +H  E + M   ME LL+   VDIV +GHVHAYER  RV    LDPCG ++IT+GDGGN E +   +                                    + QP WS FRE+SFGHG L++ NST+A W+WHRN D   E    DQV+I
Sbjct:  108 LEDNTVYYYRCGGGG-----PEYKLKTPPAQ----FPVMFAVAGDLGQTGWTKSTLDHIDLCKYDVHLLPGDLSYADYI------------------------QHRWDTFGELVEPLASARPWMVTQGNHEKESIMFFKDGFQSYNSRWKMPYEESGSSSNLYYSFEVAGAHIIMLGSYTDYDEHSDQYNWLKADVAKVDRKKTPWLIVLFHVPWYNSNEAHQDEGDRMLAAMEPLLHAASVDIVLAGHVHAYERTERVNKGKLDPCGAVHITIGDGGNREGLASKYK-----------------------------------NPQPAWSVFREASFGHGELKLANSTHAYWSWHRNDD--DESVRSDQVWI 409          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYI 1605
            L+    YYY+CG         E+ L+T P      +P   AV GDLG T  T +T+DH+ Q    + L+ GDL YA+                          Q  WD +G  +EPL S  P MV +GNHE E  P +    FE Y +R+ +P EE GS SN YYSF+  G H IMLG+Y  Y+    QY WL+ DL +VDR  TPWL+  +H PWYNS  +H  E + M + ME LLY   VDIV +GHVHAYER  RV N  LDPCG ++IT+GDGGN E                        G+ H              + QP WS FRE+SFGHG L++ NST+A W+WHRN D   E    DQV+I
Sbjct:  108 LEDNAVYYYRCGGGG-----PEYKLKTPPAQ----FPVTFAVAGDLGQTGWTQSTLDHIDQCKYDVHLLPGDLSYADYM------------------------QHLWDTFGELVEPLASARPWMVTQGNHERESIPFLKD-GFEPYNSRWKMPFEESGSSSNLYYSFEVSGAHIIMLGSYTGYDEYSNQYNWLEADLAKVDRNKTPWLLVLFHVPWYNSNEAHQNEGDRMMEAMEPLLYAASVDIVLAGHVHAYERTERVNNGKLDPCGAVHITIGDGGNRE------------------------GLAHK-----------YKNPQPAWSVFREASFGHGELKLANSTHAFWSWHRNDD--DEPVRSDQVWI 409          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSG-ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY-----------TLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYK 1575
            GL+  TKYYYK G       S+E   +T P+   +T P +  ++GDLG T N+ +T++H +Q+    +L VGDL YA++Y+             + D  IR      WD WGRF+E   +  P M   GNHEIE  P +   I F+SYL R+  P     S S F+Y+      H I+L +Y  +     Q+ WL+++L RVDR  TPWL+   H P YNS  +H+ E E MR   E    +Y VD+VF+GHVHAYER  RV N              D   P+YITVGDGGN E +   F D                                    QP++SAFRE+S+GH  LE+ N T+A++ W+RN D  K
Sbjct:  129 GLEYETKYYYKIGSGD---SSREFWFQTPPKINPDT-PYKFGIIGDLGQTYNSLSTLEHYMQSGAQAVLFVGDLAYADRYK-------------YNDVGIR------WDSWGRFVERSAAYQPWMWSAGNHEIEYMPYMGEVIPFKSYLNRYPTPHLASKSSSPFWYAIRRASAHIIVLSSYSSFVKYTPQWEWLREELKRVDREKTPWLIVLMHIPIYNSNEAHFMEGESMRAVFEKWFVRYKVDVVFAGHVHAYERSYRVSNIHYNVSSGDRFPAADESAPVYITVGDGGNQEGLAGRFRDP-----------------------------------QPDYSAFREASYGHSTLEIKNRTHAIYHWNRNDDGKK 446          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKVIS 1650
            GLKPGTKYYYKCGDSSIPAMS+EHA ETLP P  +TYP RIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDL YANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYNATGAQYAWLKDDLH++DRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGP+YITVGDGGNIE+VDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKG+FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQ+YIVRQPELCS S KV+S
Sbjct:  134 GLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPELCSPSVKVVS 520          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAK 1641
            GLKPGTKYYYKCGDSSIPAMS+EHA ETLP P  +TYP RIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDL YANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYNATGAQYAWLKDDLH++DRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGP+YITVGDGGNIE+VDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKG+FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQ+YIVRQPELCS S K
Sbjct:  134 GLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPELCSPSVK 517          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEF-GGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELC 1626
            GLKP T Y+Y+CGD SIPAMS+ +   T+P  G  +YP RIAVVGDLGLT NT+TTI HL  NDP+++L++GD+ YAN Y  T G G+ C+SC+FP +PI ETYQPRWD WGRFME L S+VP+MVIEGNHEIE Q    TF +Y +RFA PSEE GS S FYYSF+AGG+HFIMLGAYID+  +G QY WL+ DL  VDR+ TPWLVA WHPPWY++Y +HY+E ECMR EME LLY YGVDIVF+GHVHAYER NRVYNY LDPCGP+Y+TVGDGGN E++ V +AD+PG CP       E+ GG C  NF+SGPA G FCW +QP++SAFRESSFGHGILEV N T+ALWTW+RNQD+  ++  GDQ+YIVRQP+ C
Sbjct:  246 GLKPNTLYFYRCGDPSIPAMSEIYHFRTMPVSGPWSYPERIAVVGDLGLTYNTTTTISHLTSNDPNLVLLIGDVTYANLY-LTNGTGSDCYSCSFPHSPIHETYQPRWDYWGRFMENLISKVPIMVIEGNHEIEEQAENKTFVAYSSRFAFPSEESGSSSTFYYSFNAGGIHFIMLGAYIDFTRSGKQYKWLEQDLANVDRSTTPWLVATWHPPWYSTYEAHYREAECMRLEMEELLYSYGVDIVFNGHVHAYERSNRVYNYNLDPCGPVYLTVGDGGNREKMAVKYADEPGNCPEPSTAPDEYIGGFCAKNFTSGPAAGKFCWDRQPDYSAFRESSFGHGILEVKNETWALWTWYRNQDS--DNKVGDQIYIVRQPDKC 622          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPE--FGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPELCSRSAKV 1644
            GL P T Y Y+CGD SIPAMS     +T+P  G  +YP R+AVVGDLGLT NT++T+DHL+ N P ++L+VGD+ YA+ Y  T G G+ C+SC+FP  PI+ETYQPRWD WGR+M+PL S+VP+MV+EG+H+IE Q    TF SY +RFA PSEE GS S  +YSF+AGG+HFIMLGAY  YN +  QY WL+ DL   DR +TPWLVA WHPPWY++Y +HY+E ECMR EME +LY+YGVDIVF+GHVHAYER NRVYNYTLDPCGP+YITVGDGGN E++ +  AD+PG CP     TP+   GG C  NF+SGPA G FCW +QPE+SA+RESSFGHGILEV N T+ALW+WHRNQD Y+    GDQ++IVRQP+ C  +A V
Sbjct:   37 GLIPNTLYQYQCGDPSIPAMSSVSYFKTMPVSGPKSYPSRVAVVGDLGLTYNTTSTVDHLLANGPDLLLLVGDVSYADLY-LTNGTGSDCYSCSFPHTPIQETYQPRWDYWGRYMQPLVSKVPIMVLEGDHDIEQQAGNQTFVSYSSRFAFPSEESGSSSTLFYSFNAGGIHFIMLGAYTAYNKSADQYMWLEKDLANFDRNLTPWLVATWHPPWYSTYMAHYREAECMRVEMEDILYKYGVDIVFNGHVHAYERSNRVYNYTLDPCGPVYITVGDGGNREKMAIAHADEPGNCPEP-CTTPDKLMGGFCAFNFTSGPAAGKFCWDRQPEYSAYRESSFGHGILEVKNETHALWSWHRNQDFYR--YAGDQIFIVRQPDSCPVTANV 419          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1569
            L+P T YYY+CG S      QE + +T P+      P   AV GDLG T  T++T++H+   D  ++L+ GDL YA                        +T+QP WD +GR +EP  S+ P MV +GNHEIE  P +    F++Y  R+ +P +E GS SN YYSF+  G H IMLG+Y++++A   QY WL+ DL ++DR  TPW+V   H PWYN+ ++H  E E MRQ ME LLY   VD+VF+GHVHAYER  R+YN   DPCGP+Y+T+GDGGN E + + F +                          PA            S +RE SFGHG L +VN T+A W WHRN D+
Sbjct:  115 LEPATMYYYRCGGSE-----QEFSFKTPPQK----LPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA------------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEE--------------------------PAS---------PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDS 407          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFEC--MRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1566
            LKP T YYY+CG +S P    E + +T P     ++P   AVVGDLG T  T +T+DH+ + +  M ++ GDL YA                        +  QP WD +GR ++PL S+ P MV +GNHEIE  P +    F +Y  R+ +P EE GS SN YYSFD  GVH IMLG+Y D++ + AQY WL+ DL +VDR  TPW+V   H PWYNS  +H  E E   M+  ME LLYQ  VD+V +GHVHAYER  RVY    + CGP++IT+GDGGN E +   +                                    + QP+ S FRE+SFGHG L V N+T+A WTWHRN+D
Sbjct:  119 LKPNTVYYYRCGSNSGP----EFSFKTPPA----SFPITFAVVGDLGQTEWTKSTLDHISKVNYDMFMLPGDLSYA------------------------DVDQPLWDSFGRLVQPLASQRPWMVTQGNHEIEKIPVLHTHAFTAYNARWHMPYEESGSDSNLYYSFDVAGVHVIMLGSYTDFDPSSAQYQWLQVDLGKVDRGRTPWIVVLIHAPWYNSNKAHQGESESIDMKDAMEDLLYQARVDVVLAGHVHAYERFTRVYKDEANNCGPVHITIGDGGNREGLASKYK-----------------------------------NPQPKISVFREASFGHGQLVVANATHAQWTWHRNED 413          

Query:  493 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYI 1605
            L+ GT Y+Y+CG         E   +T P      +P   AV GD+G T  T +T+DH+ Q    + L+ GDL YA+                          Q RWD +G  ++PL S  P MV +GNHE E  P +    F SY +R+ +P EE GS SN YYSF+  GVH IMLG+Y DY+    QY WLK DL +VDR  TPWLVA +H PWYNS  +H  E + M   ME LLY   VDIV +GHVHAYER  RV +   D CG ++IT+GDGGN E                        G+ H              +  PEWS FRE+SFGHG L++VNST+A WTWHRN D   E    DQV+I
Sbjct:  110 LEHGTVYFYQCG-----GQDPEFQFKTPPAQ----FPITFAVAGDMGQTGWTKSTLDHIEQCKYDLHLLPGDLSYADYM------------------------QSRWDTFGELVQPLASARPWMVTQGNHEKENIPLLKD-GFASYNSRWKMPYEESGSSSNLYYSFEVAGVHAIMLGSYTDYDEYSDQYRWLKADLSKVDRQKTPWLVALFHVPWYNSNKAHQGEGDSMMAAMEPLLYAASVDIVLAGHVHAYERTKRVNSGKSDTCGAVHITIGDGGNRE------------------------GLAHKYI-----------NPSPEWSVFREASFGHGELKIVNSTHAFWTWHRNDD--DEPVRSDQVWI 411          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRV----YNYTL-------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYK 1575
            GL+  TKYYYK G       S+E    T P+   N+      ++GDLG T N+ +T++H +Q+    +L +GDL YA++Y+             + +  +R      WD WGRF+E  T+  P +   GNHEIE  P +  +T F+SYL R+A P     S +  +Y+      H I+L +Y  +     Q+ WL+++L RVDR  TPWL+   H P YNS  +HY E E MR   E+    Y VD++F+GHVHAYER  R+    YN T        D   P+YITVGDGGN E +   F D                                    QP++SAFRE+++GH  LE++N T+AL+ W+RN D  K
Sbjct:   86 GLEHDTKYYYKIGSGD---SSREFWFTTPPKIDPNSR-YTFGIIGDLGQTFNSLSTLEHYMQSKGQAVLFLGDLSYADRYQ-------------YNEVGLR------WDTWGRFVEQSTAYHPWIWSAGNHEIEFMPYLGEVTPFKSYLQRYATPYLASKSSNPLWYAIRRASAHIIVLSSYSPFVKYTPQWRWLEEELKRVDREKTPWLIVLMHVPIYNSNDAHYMEGESMRVVFESWFVHYKVDVIFAGHVHAYERSYRISNIHYNITSGDQNPIPDKSAPVYITVGDGGNQEGLAGRFTDP-----------------------------------QPDYSAFREAAYGHSTLEIINRTHALYHWNRNDDGKK 403          

Query:  490 GLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRV----YNYTL-------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYK 1575
            GL+  TKYYYK G       S+E    T P+   N+      ++GDLG T N+ +T++H +Q+    +L +GDL YA++Y+             + +  +R      WD WGRF+E  T+  P +   GNHEIE  P +  +T F+SYL R+A P     S +  +Y+      H I+L +Y  +     Q+ WL+++L RVDR  TPWL+   H P YNS  +HY E E MR   E+    Y VD++F+GHVHAYER  R+    YN T        D   P+YITVGDGGN E +   F D                                    QP++SAFRE+++GH  LE++N T+AL+ W+RN D  K
Sbjct:  129 GLEHDTKYYYKIGSGD---SSREFWFTTPPKIDPNSR-YTFGIIGDLGQTFNSLSTLEHYMQSKGQAVLFLGDLSYADRYQ-------------YNEVGLR------WDTWGRFVEQSTAYHPWIWSAGNHEIEFMPYLGEVTPFKSYLQRYATPYLASKSSNPLWYAIRRASAHIIVLSSYSPFVKYTPQWRWLEEELKRVDREKTPWLIVLMHVPIYNSNDAHYMEGESMRVVFESWFVHYKVDVIFAGHVHAYERSYRISNIHYNITSGDQNPIPDKSAPVYITVGDGGNQEGLAGRFTDP-----------------------------------QPDYSAFREAAYGHSTLEIINRTHALYHWNRNDDGKK 446          

Query:  505 TKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQND--PSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSG-ITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTL-----------DPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY 1572
            T YYY  G   I    ++    T PE G +  P    ++GDLG T +++ T+ H   N      +L +GDL YA+ Y                  P  +    RWD WGRF E   +  P +   GNHEI+  P++   I F+ Y  R+ VP    GS + F+YS      + I+L +Y  Y  +  QY WL+ +L +V+R+ TPWL+   H PWYNSY SHY E E MR   E    +Y VD+VF+GHVHAYER  RV N              D   P+Y+TVGDGGN+E +     +                                    QP++S FRE+SFGHGI ++ N T+A ++WHRNQ+ Y
Sbjct:  140 TTYYYVVG---IGNTERQFWFTTPPEIGPDV-PYTFGLIGDLGQTFDSNRTLTHYELNPLKGQTVLYLGDLSYADDY------------------PCHDNV--RWDTWGRFTERSAAYQPWIWSAGNHEIDFSPELGETIPFKPYTHRYYVPYNASGSTAPFWYSIKRASAYIIVLASYSAYGPSTPQYQWLETELPKVNRSETPWLIVIMHCPWYNSYYSHYMEGEGMRVTFEPWFVKYKVDVVFNGHVHAYERSERVSNVAYNVVNANCTPVKDQSAPVYVTVGDGGNLEGLSTVMTE-----------------------------------PQPDYSLFREASFGHGIFDIKNRTHAYFSWHRNQEGY 452