ppa003722m, ppa003722m (mRNA) Prunus persica

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQP 1527
            IPTTLEGPF+P T  FD  LRRGS+DLPMDHPRL++NVT  FPEQI+LAISSPTSMW+SW+TGD+QIG NVTPLDPS V SEV YGK S KY SVK G S VYSQLYPFEGLLNYTSGI+HHVR+D L+PGTKYYYKCGDSS PAMS E+ FETLP+P    YP RIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL+YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYN TGAQYAWLK DLHQ+DR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIEQV+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW++QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQIYIVRQP
Sbjct:   13 IPTTLEGPFQPVTHSFDSRLRRGSDDLPMDHPRLRRNVTSFFPEQISLAISSPTSMWVSWITGDSQIGSNVTPLDPSTVASEVWYGKRSRKYSSVKSGFSTVYSQLYPFEGLLNYTSGIIHHVRLDDLEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQP 514          

Query:    4 AVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEF-GGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            A   + IPTTL+GPF P T  FD SLR  + DLP   PR+++ V    PEQI++A+S+   S+WISW+TG+ QIG N+ PL+P  V S VRYG           G S+VY+QLYPFEGL NYTSGI+HHVR+ GLKP T+YYY+CGD +I AMS  ++F T+P+    +YP +I ++GDLGLT N++ TIDHLI N P ++L+VGD+TYANQY  T G G+ C+SC+FP  PI ETYQPRWD WGRFM+ L S+VPMMVIEGNHEIE Q     F +Y +RFA PS+ESGS S FYYSF+AGG+HFIMLGAY  YN +  QY WL+ DL ++DR++TPWL+AAWHPPWY+SY +HY+E ECMRQEME LLY YGVDIVF+GHVHAYER NRVYNY LD CGPV+I VGDGGN E++ ++ AD PGKCP        F GG C  NF+ GPA G FCW++QP++SAFRESSFGHGILEV N T+ALWTW+RNQD+   D+ GDQIYIVR P+
Sbjct:   17 AAIHARIPTTLDGPFTPVTVPFDQSLRGKAVDLPDTDPRVRRRVKGFEPEQISVALSASFDSVWISWITGEFQIGYNIKPLNPKTVSSVVRYGTLRYPLRRKVMGYSLVYNQLYPFEGLQNYTSGIIHHVRLAGLKPSTRYYYRCGDPTIGAMSNIYSFRTMPVSGPRSYPRKIGIIGDLGLTYNSTATIDHLISNKPDLVLLVGDVTYANQY-LTNGTGSDCYSCSFPQTPIHETYQPRWDYWGRFMQNLVSKVPMMVIEGNHEIEEQAEKKNFVAYSSRFAFPSKESGSASTFYYSFNAGGIHFIMLGAYAAYNKSADQYKWLERDLAKVDRSITPWLIAAWHPPWYSSYKAHYREVECMRQEMEELLYSYGVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIMVGDGGNREKMAIEHADAPGKCPEPSTTPDTFIGGFCATNFTFGPAAGKFCWDRQPDFSAFRESSFGHGILEVKNDTWALWTWYRNQDS--RDNAGDQIYIVRTPD 524          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPE--FGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF+P T   D S R  + DLP   PRL++ V    PEQI++ +S+   S+WISWVTG+ QIG N+ PLDP  V S+V YGK+  +   +  G S+VY+QLYPFEGL NYTSGI+HHVR+ GLKP T YYY+CGD+SIPA+S+ H F+T+       YP+RIAVVGDLGLT NT++TI HL+ N+P +I+ VGD+ YAN Y  T G G+ C+SC+F   PI ETYQPRWD WGRFM+PL S++P+MV+EGNHEIE Q    TF +Y +RFA PS+ESGS S FYYSF+AGG+HFIMLGAY+ Y+ +G QY WL+ DL ++DR VTPW+VA WHPPWY++Y +HY+E ECMR  +E LLY YGVDIVFSGHVHAYER NRVYNY LD CGPV+ITVGDGGN E++ +  AD+ G+CP     TP+   GG C  NF+SGPA G FCW++QP++SA+RE+SFGHGILE+ N T ALWTWHRNQD Y  +  GDQIYIVRQP+
Sbjct:   27 IPTTLDGPFKPVTVPLDTSFRGNAVDLPHTDPRLQRTVQGFEPEQISVTLSATYDSVWISWVTGEFQIGDNIKPLDPKSVASQVFYGKKKHRLVHMSNGHSLVYNQLYPFEGLQNYTSGIIHHVRLTGLKPETVYYYQCGDASIPALSDIHHFKTMVASGPRGYPNRIAVVGDLGLTYNTTSTISHLMSNNPDLIVFVGDVCYANMY-LTNGTGSDCYSCSFSQTPIHETYQPRWDYWGRFMQPLISKIPIMVVEGNHEIEEQAENQTFVAYSSRFAFPSKESGSSSTFYYSFNAGGIHFIMLGAYISYDKSGEQYKWLERDLKKVDRKVTPWMVATWHPPWYSTYKAHYREAECMRVALEDLLYNYGVDIVFSGHVHAYERSNRVYNYTLDPCGPVHITVGDGGNREKMAIPHADEHGQCPEP-STTPDKYMGGFCAFNFTSGPAAGRFCWDRQPDYSAYRETSFGHGILEMKNETVALWTWHRNQDFY--NLAGDQIYIVRQPD 528          

Query:  148 PEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1479
            P+Q+ +++     M +SW+T D                S V YGK  GKYE+   G    Y+  +       Y+SG +HHV I  L+ GT YYY+CG S      +E  F+T P    S++P   AVVGDLG T  T++T+ H+ + +  ++L+ GDL+YA                        +++QP WD +GR +EP  S  P MV EGNHEIE  P +    FK++ +R+ +P +ESGS SN YYSF+  G H IMLG+Y +++   AQY WLK DL ++DR  TPWL+   H PWYN+  +H  E E MR+ ME LLY+  VD+VF+GHVHAYER  RVY    D CGP+++T+GDGGN E + + F                            P   S         S +RE SFGHG L ++N T+A W+WHRN D+
Sbjct:  124 PQQVHISLVGRDRMKVSWITDD------------KSARSIVEYGKMPGKYEASATGEHTSYNYFF-------YSSGKIHHVEIGPLEAGTVYYYRCGGSG-----QEFYFKTPP----SSFPIEFAVVGDLGQTEWTASTLTHVNRTNYDVLLLPGDLSYA------------------------DSHQPLWDCFGRLVEPYASHRPWMVTEGNHEIEIFPIIYPDGFKAFNSRWPMPFQESGSTSNLYYSFEVAGCHVIMLGSYAEFDEKSAQYKWLKGDLGKVDRRRTPWLIVLIHAPWYNTNLAHKGEGESMRKAMEKLLYEARVDVVFAGHVHAYERFTRVYKNKADECGPIHVTIGDGGNREGLALTF--------------------------EKPTSASL--------SVYREPSFGHGRLRILNQTHAFWSWHRNNDS 483          

Query:  142 NFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEP-QVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYI 1515
            + P+Q+ +++SS   M I+W+T D                S V+YG   GKY S+  G S  YS L+       Y+SG +HH  I  L+  T YYY+CG        +   F+    P+Q  +P   AV  DLG T  T +T+DH+   +  + L+ GDL+YA+                          Q RWD +G  ++PL S  P MV EGNHE E        F+SY +R+ +P +ESGS SN YYSF+  GVH +MLG+Y  Y+    QY+WLK DL ++DR  TPWL+   H PWYNS  +H  E + M + +E LLY   VD+VF+GHVHAYER  RVYN   D CGP++IT+GDGGN E +   + D                                    QPEWS FRE+SFGHG L++VN T+A W+WHRN D   E    D+++I
Sbjct:   40 SLPQQVHISLSSEKHMRITWITDDEY------------APSIVQYGTSPGKYTSITLGGSTSYSYLF-------YSSGKIHHTVIGPLEHDTIYYYRCG-------GQGPEFQLKTPPAQ--FPITFAVAADLGQTGWTKSTLDHIDGCNYDVHLLPGDLSYADYL------------------------QRRWDTFGELVQPLASARPWMVTEGNHEQENIPFFKDGFESYNSRWTMPYQESGSPSNLYYSFEVAGVHVVMLGSYAAYDLNSNQYSWLKTDLSRVDRKRTPWLLVLLHVPWYNSNKAHQGEGDRMMETLEPLLYAANVDLVFAGHVHAYERSKRVYNGRSDPCGPIHITIGDGGNREGLATRYND-----------------------------------PQPEWSVFREASFGHGELKIVNLTHAFWSWHRNDD--DEPVRSDEVWI 409          

Query:  148 PEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEP--QVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHY--QEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            P+Q+ ++++    M I+W+T      K+ TP       +EV YG   G+  S   G +  Y           YTSG +H V I  L   T YYY+CG S       E +F+T P    S +P R+AV GD G T  T +T+DH+ +++  ++L+ GDL+YA                        + YQP WD +GR +EPL S+ P M   GNH++E    V    F SY  R+ +P EESGS SN YYSF+  GVH ++LG+Y D+ +   QY WL+ DL ++DR  TPWLV   H PWYNS S+H   +E + MR  ME +LY+  VD+VF+GHVHAYER +RVY    D+CGPVYIT+GDGGN E +   + D                                    +P+ S FRE+SFGHG L VV+     WTWHRN D
Sbjct:   48 PDQVRISMAGADKMRITWMT------KDETP-------AEVHYGTVQGELGSSATGSTRSYKYA-------TYTSGTIHDVLIGPLNANTVYYYRCGSSG-----PEFSFKTPP----SQFPIRLAVAGDFGQTEWTKSTLDHISKSNYDLLLLAGDLSYA------------------------DFYQPLWDSFGRLVEPLASQRPWMTATGNHDVEKIIVVHPEKFTSYNARWHMPFEESGSTSNLYYSFEVAGVHVVVLGSYTDFGSDSDQYKWLQADLGKVDRKRTPWLVVMLHAPWYNSNSAHQGEEESDGMRDSMEEILYKARVDVVFAGHVHAYERFDRVYQGKTDKCGPVYITIGDGGNREGLATKYND-----------------------------------PKPDISLFREASFGHGQLNVVDENTMEWTWHRNDD 406          

Query:  148 PEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFK--SYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHY--QEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            PEQ+ +++     M I+WVT      K+ TP       +EV YG   G+  S   G +  Y  +        YTSG +H V I  L   T YYY+CG S       E +F+T P    S +P RIAV GD G T  T +T+DH+ +++  ++L+ GDL+YA                        + YQP WD +GR +EPL S+ P M   GNH++E  +     K  SY  R+ +P EESGS SN YYSF+  GVH ++LG+Y D+ +   QY WL+ DL ++DR  TPWLV   H PWYNS S+H   +E + MR  ME +LY+  VD+VF+GHVHAYER +RVY    D+CGPVYIT+GDGGN E +   + D                                    +P+ S FRE+SFGHG L VV+     WTWHRN D
Sbjct:  458 PEQVHISMVGADKMRITWVT------KDETP-------AEVHYGTAQGQLGSSATGSTRSYKYVV-------YTSGTIHDVVIGPLNANTVYYYRCGSSG-----PEFSFKTPP----SQFPIRIAVAGDFGQTEWTKSTLDHISKSNYDLLLLAGDLSYA------------------------DFYQPLWDSFGRLVEPLASQRPWMTATGNHDVEKIIVVHPEKCTSYNARWHMPFEESGSTSNLYYSFEVAGVHVVVLGSYSDFGSDSDQYKWLQADLGKVDRKRTPWLVVMLHAPWYNSNSAHQGEEESDGMRDSMEEILYKARVDVVFAGHVHAYERFDRVYQGKTDKCGPVYITIGDGGNREGLATKYID-----------------------------------PKPDISLFREASFGHGQLNVVDGNTMEWTWHRNDD 816          

Query:   91 SNDLPMDHPRLKKNVTLNFPEQIALAISS--PTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY-----------MLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYK 1485
            S D+P+D+         N P+Q+ +        ++ I+WVT D          +P    S+V YG    KY+   +G    Y+         NY+SG +HH  + GL+P TKYYYK GD      S E  F+T P     T  +   ++GDLG T N+ +T++H +Q+    +L VGDL+YA++Y              F D  +R      WD WGRF+E   +  P +   GNHE+E  P +  +  FKSYL R+A P   S S +  +Y+      H I+L +Y  +     Q+ WL+++L ++DR  TPWL+   H P Y+S  +HY E E MR   E+      VD++F+GHVHAYER  R+ N            + D+  PVYITVGDGGN E +   F D                                    QPE+S+FRE+S+GH  LE+ N T+A + W+RN D  K
Sbjct:   43 STDIPLDNEAFAIPKGHNAPQQVHITQGDYDGKAVIITWVTTD----------EPGS--SKVLYGTLEKKYDFSAEGNVTNYT-------FSNYSSGYIHHCLVHGLEPDTKYYYKIGDGG---SSREFWFQTPPKIDPDT-SYTFGIIGDLGQTYNSLSTLEHYMQSGAQTVLFVGDLSYADRYE-------------FNDVGVR------WDSWGRFVERSAAYQPWIWTAGNHEVEYMPNMGEVLPFKSYLHRYATPYMASQSSNPLWYAVRRASAHIIVLSSYSPFVKYTPQWKWLREELKRVDREKTPWLIVLMHAPMYSSNVAHYMEGESMRAVFESWFVHAKVDLIFAGHVHAYERSYRISNIHYNITNGDRYPIPDKSAPVYITVGDGGNQEGLAGRFVDP-----------------------------------QPEYSSFREASYGHSTLEIKNRTHAFYHWNRNDDGKK 446          

Query:   97 DLPMDHPRLKKNVTLNFPEQIALAISSPTS--MWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPS--MILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSG-ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYML-----------DRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY--KEDS 1494
            D+P+D    +  +  N P+Q+ +         + +SWVT D + G N            V Y  E+ K ++  +G+ V Y          NYTSG +HH  I  L+  TKYYY  G    P    +  F T P       P+   ++GDLG + +++ T+ H   N      +L VGDL+YA+ Y                  P  +    RWD WGRF E  T+  P +   GNHEI+  P++   I FK Y  R+ VP   S S + F+YS      + I+L +Y  Y     QY WL+ +L +++R+ TPWL+   H PWYNSY+ HY E E MR   E    QY VD+VF+GHVHAYER  RV N              D+  PVYIT+GDGGN+E +  +  +                                    QP++SA+RE+SFGH I ++ N T+A ++WHRNQD Y  K DS
Sbjct:   46 DMPLDSDVFRVPLGYNAPQQVHITQGDHEGRGVIVSWVTVD-EPGSNT-----------VLYWSENSKRKNRAEGIMVTYK-------FYNYTSGYIHHCTIKNLEFNTKYYYVVGIGHTP---RKFWFVTPPKVGPDV-PYTFGLIGDLGQSYDSNMTLTHYELNPAKGKTVLFVGDLSYADNY------------------PNHDNV--RWDTWGRFTERSTAYQPWIWTAGNHEIDFVPEIGEFIPFKPYSHRYHVPYRASDSTAPFWYSIKRASAYIIVLASYSAYGKYTPQYKWLEKELPKVNRSETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQYKVDVVFAGHVHAYERSERVSNIAYNVINGICTPVNDQSAPVYITIGDGGNLEGLATNMTEP-----------------------------------QPKYSAYREASFGHAIFDIKNRTHAHYSWHRNQDGYAVKADS 453          

Query:  100 LPMDHPRLKKNVTLNFPEQIALAISSPTS--MWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPS--MILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSG-ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYML-----------DRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY--KEDS 1494
            +P+D    +  +  N P+Q+ +         + +SWVT D + G N            V Y  E  K ++  +G+ V Y          NYTSG +HH  I  L+  TKYYY  G    P    +  F T P       P+   ++GDLG + +++ T+ H   N      +L VGDL+YA++Y                          RWD WGRF E  T+  P +   GNHEI+  P++   I FK Y  R+ VP   S S + F+YS      + I+L +Y  Y     Q+ WL+ +L +++R+ TPWL+   H PWYNSY+ HY E E MR   E    QY VD+VF+GHVHAYER  RV N              D+  PVYIT+GDGGN+E +  +  +                                    QP++SA+RE+SFGH I +  N T+A ++WHRNQD Y  K DS
Sbjct:    1 MPLDSDVFRVPLGYNAPQQVHITQGDHEGRGVIVSWVTVD-EPGSNT-----------VLYWSEKSKRKNRAEGIMVTYK-------FYNYTSGYIHHCTIKNLEFNTKYYYVVGIGHTP---RKFWFVTPPKVGPDV-PYTFGLIGDLGQSYDSNMTLTHYELNPAKGKTVLFVGDLSYADRYPNYDNV--------------------RWDTWGRFTERSTAYQPWIWTAGNHEIDFAPEIGEFIPFKPYSHRYHVPYRASDSTAPFWYSIKRASAYIIVLSSYSAYGKYTPQFMWLEKELPKVNRSETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQYKVDVVFAGHVHAYERSERVSNIAYNVINGICTPVNDQSAPVYITIGDGGNLEGLATNMTEP-----------------------------------QPKYSAYREASFGHAIFDTKNRTHAQYSWHRNQDGYAVKADS 407          

Query:   91 SNDLPMDHPRLKKNVTLNFPEQIALAISS--PTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY-----------MLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            S D+P+D+         N P+Q+ +        ++ +SWVT D           PSKV    +YG     Y+   +G +  Y+          Y SG +HH  +DGL+  TKYYYK G  +    S+E  F+T P       P+   ++GDLG T N+ +T++H + ++   +L +GDL+YA++Y+             + D  +R      WD WGRF+E   +  P +   GNHEIE  P +  +  FKSYL RF  P   S S S  +Y+      H I+L +Y  +     Q+ WL ++  +++R  TPWL+   H P YNS  +H+ E E MR   E+      VDIVF+GHVHAYER  R+ N            + D   PVYITVGDGGN E +   F D                                    QP++SAFRE+S+GH  LE+ N T+A + W+RN D
Sbjct:   22 SVDIPLDNKVFAVPKGYNAPQQVHITQGDYDGKAVIVSWVTTDEP--------GPSKV----QYGTSEKTYDYTAEGTTTNYT-------FYKYQSGYIHHCLVDGLEFDTKYYYKIGSGN---SSQEFWFQTPPEIDPDA-PYIFGIIGDLGQTYNSLSTLEHYMHSEGQTVLFLGDLSYADRYQ-------------YNDVGVR------WDTWGRFVEQSAAYQPWIWSAGNHEIEYMPYMGEVLPFKSYLYRFPTPYAASKSSSPLWYAIRRASAHIIVLSSYSPFVTYTPQWLWLAEEFKRVNREKTPWLIVLMHVPIYNSNEAHFMEGESMRAAFESWFILNKVDIVFAGHVHAYERSYRISNIHYSVSSGDPYPVPDESAPVYITVGDGGNQEGLAGRFRDP-----------------------------------QPDYSAFREASYGHSTLEIKNRTHAFYRWNRNSD 422          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF+P TRRFDPSLRRGS+DLPM+HPRLKKN T NFPEQI+LAISSPTSMW+SWVTG+AQIG +V PLDP+ V SEV YGKESGKY S  KG S VY+QLYPFEGL NYTSGI+HHVRIDGL+PGTKY+YKCGDSSIPAMSEEH FETLP+PS + YPHRIA++GDLGLTSN+STTIDH+I NDPSMILMVGDLTYANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITFKSYLTR+AVPSEESGS SNFYYSFDAGG+HF+MLGAYVDYN+TGAQY+WLK DL+Q+DR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQIY+VRQPE
Sbjct:    1 IPTTLDGPFKPVTRRFDPSLRRGSDDLPMNHPRLKKNATSNFPEQISLAISSPTSMWVSWVTGEAQIGSDVIPLDPASVASEVWYGKESGKYASRGKGNSTVYTQLYPFEGLSNYTSGIIHHVRIDGLEPGTKYFYKCGDSSIPAMSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPE 503          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQP 1527
            IPTTLEGPF+P T  FD  LRRGS+DLPMDHPRL++NVT  FPEQI+LAISSPTSMW+SW+TGD+QIG NVTPLDPS V SEV YGK S KY SVK G S VYSQLYPFEGLLNYTSGI+HHVR+D L+PGTKYYYKCGDSS PAMS E+ FETLP+P    YP RIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL+YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYN TGAQYAWLK DLHQ+DR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIEQV+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW++QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQIYIVRQP
Sbjct:   13 IPTTLEGPFQPVTHSFDSRLRRGSDDLPMDHPRLRRNVTSFFPEQISLAISSPTSMWVSWITGDSQIGSNVTPLDPSTVASEVWYGKRSRKYSSVKSGFSTVYSQLYPFEGLLNYTSGIIHHVRLDDLEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQP 514          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            MAVA++ IPTTL+GPF+P TRRFDPSLRRGS+DLPM HPRL+KNVT NFPEQIALAISSPTSMW+SWVTGDAQIG NVTP+DP+ VGSEV YGK+SGKY SV KG SVVYSQLYPFEGL NYTSGI+HHV++ GL+PGT+YYYKCGDSSIPAMS+EH FET P PS + YP RIAV+GDLGLTSN+++TIDHL  NDPSMILMVGDLTYANQY TTGGKGASC+SCAFPDAPIRETYQPRWDGWGRFMEPLTS +PMMVIEGNHEIEPQ  GITFKSYLTRFAVP+EESGSKSNFYYSFDAGG+HFIMLGAYVDYN+TGAQ+AWLK DL  +DR+VTPWLVAAWH PWYNSY+SHYQEFECMR EME LL++Y VDIVF GHVHAYERMNRV+NY LD CGPVYITVGDGGNIE+VDVD ADDPGKCPSAGDN PEFGGVC  NFS+GPAKG+FCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YKE++ GDQIYIVRQPE
Sbjct:    1 MAVAETHIPTTLDGPFDPVTRRFDPSLRRGSDDLPMTHPRLRKNVTSNFPEQIALAISSPTSMWVSWVTGDAQIGLNVTPVDPASVGSEVWYGKKSGKYTSVGKGDSVVYSQLYPFEGLWNYTSGIIHHVKLKGLEPGTRYYYKCGDSSIPAMSQEHYFETFPKPSPNNYPARIAVIGDLGLTSNSTSTIDHLNYNDPSMILMVGDLTYANQYLTTGGKGASCYSCAFPDAPIRETYQPRWDGWGRFMEPLTSEIPMMVIEGNHEIEPQAGGITFKSYLTRFAVPAEESGSKSNFYYSFDAGGIHFIMLGAYVDYNSTGAQFAWLKKDLQSVDRSVTPWLVAAWHSPWYNSYASHYQEFECMRLEMEELLFRYRVDIVFDGHVHAYERMNRVFNYTLDPCGPVYITVGDGGNIEKVDVDHADDPGKCPSAGDNIPEFGGVCKSNFSTGPAKGNFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDNYKENAVGDQIYIVRQPE 510          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWG-----------------------------------RFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            M V++  IPTTL+GPF+P TRRFD SLRRGS+DLPM HPRLK NVTLNFPEQIALAISSPTSMWISW+TG +QIG NVTPLDP+ +GSEV YGK+SGKY +V KG S+VYSQLYPFEGLLNYTSGI+HHV+++GL+PGT+YYYKCGDSSIPAMS+E+ FET   PS   YP RIAV+GDLGLTSN+STT+DHL  NDPSMILM+GDLTYANQY TTGGKGASCFSCAFPDAPIRETYQPRWDGWG                                   RFM+PLTS+VPMMVIEGNHEIEPQ  GITFKSYLTRFAVP+EESGSKSNF+YSFD GG+HFIMLGAYVDYN TGAQ+ WLK DL  +DR+VTPWLVA  HPPWYNSY+SHYQEFECMR EMEALLYQY VDI+F+GHVHAYERMNRVYNY LD CGP+YITVGDGGNIE+VDVD AD+PGKCPS+GDN PEFGGVCH NF+ GPAKG+FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD+YKE++ GDQIYIVRQPE
Sbjct:   22 MVVSKRHIPTTLDGPFKPVTRRFDSSLRRGSDDLPMTHPRLKMNVTLNFPEQIALAISSPTSMWISWITGKSQIGLNVTPLDPASIGSEVWYGKKSGKYTNVGKGDSLVYSQLYPFEGLLNYTSGIIHHVKLEGLEPGTRYYYKCGDSSIPAMSQENYFETFAKPSPKNYPARIAVIGDLGLTSNSSTTVDHLSYNDPSMILMIGDLTYANQYLTTGGKGASCFSCAFPDAPIRETYQPRWDGWGSNCFPKLSTSVTSAYASRISSKDRWYDLLIRCLTIRFMQPLTSKVPMMVIEGNHEIEPQADGITFKSYLTRFAVPAEESGSKSNFFYSFDTGGIHFIMLGAYVDYNKTGAQFDWLKKDLQNVDRSVTPWLVATMHPPWYNSYASHYQEFECMRLEMEALLYQYRVDIIFNGHVHAYERMNRVYNYTLDPCGPIYITVGDGGNIEKVDVDHADEPGKCPSSGDNIPEFGGVCHSNFTFGPAKGNFCWKKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDSYKENAVGDQIYIVRQPE 566          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTLEGPF+P TRRFD SLRRGS+DLPMDHPRL KNVT +FPEQIALA+SS TSMW+SWVTG+AQIG NV PLDP  V SEV YGKESGKY S KKG S VYSQLYPFEGL+NYTSGI+HHV IDGL+PGTKYYYKCGDSSIPAMSEE+ F+TLP+PS  +YPHRIAV+GDLGL+SN+STTIDHL  NDPS+I+MVGDLTYANQY TTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPL SRVPMMVIEGNHEIEPQV+GITFKSYLTRFAVPSEESGS SNFYYSFDAGG+HFIMLGAYVDYN TG+QYAWLK+DL+Q+DRT TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYER+NRVYNY LD CGPVYITVGDGGNIEQVDV+ ADD                                   QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQIYIVRQPE
Sbjct:   26 IPTTLEGPFQPVTRRFDSSLRRGSDDLPMDHPRLLKNVTGDFPEQIALALSSSTSMWVSWVTGNAQIGSNVVPLDPGSVASEVWYGKESGKYTSKKKGNSTVYSQLYPFEGLVNYTSGIIHHVIIDGLEPGTKYYYKCGDSSIPAMSEEYFFQTLPLPSPYSYPHRIAVIGDLGLSSNSSTTIDHLATNDPSLIIMVGDLTYANQYLTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLISRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSNSNFYYSFDAGGIHFIMLGAYVDYNTTGSQYAWLKEDLNQVDRTKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERINRVYNYTLDPCGPVYITVGDGGNIEQVDVEHADD-----------------------------------QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYIVRQPE 493          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRY-----------GKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSI---PAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPFEPATR FD +LR+GS+D+P+  PRL        PEQIALA SS  TS+W+SWVTG+AQ+G ++TPLDPS V SEV Y           G  SG Y  V +G + VYSQLYP+ GLLNYTSG +HHVR+ GL+P T+YYY+CGDSS+     +S E +FETLP  + + YP R+AVVGDLGLT N+++T++HL +NDPS++++VGD+TYANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNHEIEPQ  G  +TF SYL RFAVPSEESGS + FYYSF+AGG+HFIMLGAYVDYN TGAQY+WL+ DL ++DR VTPW+VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NY LD CGPVYIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQIYIVRQP+
Sbjct:   36 IPTTLDGPFEPATRAFDRALRQGSDDVPLTDPRLAPRARPPAPEQIALAASSDATSVWVSWVTGEAQVGSHLTPLDPSTVRSEVWYSERPSPTAAAAGDVSGHYPHVARGKAEVYSQLYPYPGLLNYTSGAIHHVRLRGLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHEIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWVVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPD 555          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRY-----------GKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSI---PAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPFEPATR FD +LR+GS+D+P+  PRL        PEQIALA SS  TS+W+SWVTG+AQ+G ++TPLDPS V SEV Y           G  SG Y  V +G + VYSQLYP+ GLLNYTSG +HHVR+ GL+P T+YYY+CGDSS+     +S E +FETLP  + + YP R+AVVGDLGLT N+++T++HL +NDPS++++VGD+TYANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNHEIEPQ  G  +TF SYL RFAVPSEESGS + FYYSF+AGG+HFIMLGAYVDYN TGAQY+WL+ DL ++DR VTPW+VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NY LD CGPVYIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQIYIVRQP+
Sbjct:   36 IPTTLDGPFEPATRAFDRALRQGSDDVPLTDPRLAPRARPPAPEQIALAASSDATSVWVSWVTGEAQVGSHLTPLDPSTVRSEVWYSERPSPTAAAAGDVSGHYPHVARGKAEVYSQLYPYPGLLNYTSGAIHHVRLRGLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHEIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWVVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPD 555          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISS-PTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYG-------------KESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPA-MSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF PATR FD SLRRGS D+P+   RL        PEQI+LA S+ PTS+W+SWVTG AQ+G ++TPLDP+ + SEV YG             KE   Y  V +G + VYSQLYP+ GLLNYTSG++HHVR+ GL P T+YYY+CGDSS+ A +SEE +F TLP P+   YP R+AVVGDLGLT N+++T+DHL +NDPS++LMVGD+TYANQYRTTGG+G  CFSC+FPDAPIRE+YQPRWDGW RFMEPL SR+PMMVIEGNHEIEPQ  G  +TF SY  RFAVP+EESGS S FYYSFDAGG+HFIMLGAYVDYN TGAQY+WLK DL ++DR VTPW+VA+WH PWYNSYSSHYQEFECMRQEME LLYQ+ VDIVFSGHVHAYERMNRV+NY LD CGPVYI +GDGGNIE++D+D ADDPGKCPS GDN PEFGG+CHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY EDS GDQIYIVRQP+
Sbjct:   36 IPTTLDGPFTPATRAFDRSLRRGSEDVPLSDARLAPRARPPSPEQISLAASANPTSLWVSWVTGRAQVGSHLTPLDPTSIRSEVLYGARPSSSSAAGAGEKEEDGYPHVARGSAEVYSQLYPYPGLLNYTSGVIHHVRLSGLAPSTRYYYRCGDSSLKAGLSEERSFTTLPAPAPGAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSLVLMVGDMTYANQYRTTGGRGVPCFSCSFPDAPIRESYQPRWDGWARFMEPLASRIPMMVIEGNHEIEPQGHGGAVTFASYSARFAVPAEESGSNSKFYYSFDAGGIHFIMLGAYVDYNRTGAQYSWLKKDLQRVDRAVTPWVVASWHSPWYNSYSSHYQEFECMRQEMEGLLYQHRVDIVFSGHVHAYERMNRVFNYTLDPCGPVYIIIGDGGNIEKIDIDHADDPGKCPSPGDNHPEFGGLCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEDSVGDQIYIVRQPD 555          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISS-PTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYG-------------KESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPA-MSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF PATR FD SLRRGS D+P+   RL        PEQI+LA S+ PTS+W+SWVTG AQ+G ++TPLDP+ + SEV YG             KE   Y  V +G + VYSQLYP+ GLLNYTSG++HHVR+ GL P T+YYY+CGDSS+ A +SEE +F TLP P+   YP R+AVVGDLGLT N+++T+DHL +NDPS++LMVGD+TYANQYRTTGG+G  CFSC+FPDAPIRE+YQPRWDGW RFMEPL SR+PMMVIEGNHEIEPQ  G  +TF SY  RFAVP+EESGS S FYYSFDAGG+HFIMLGAYVDYN TGAQY+WLK DL ++DR VTPW+VA+WH PWYNSYSSHYQEFECMRQEME LLYQ+ VDIVFSGHVHAYERMNRV+NY LD CGPVYI +GDGGNIE++D+D ADDPGKCPS GDN PEFGG+CHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY EDS GDQIYIVRQP+
Sbjct:   36 IPTTLDGPFTPATRAFDRSLRRGSEDVPLSDARLAPRARPPSPEQISLAASANPTSLWVSWVTGRAQVGSHLTPLDPTSIRSEVLYGARPSSSSAAGAGEKEEDGYPHVARGSAEVYSQLYPYPGLLNYTSGVIHHVRLSGLAPSTRYYYRCGDSSLKAGLSEERSFTTLPAPAPGAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSLVLMVGDMTYANQYRTTGGRGVPCFSCSFPDAPIRESYQPRWDGWARFMEPLASRIPMMVIEGNHEIEPQGHGGAVTFASYSARFAVPAEESGSNSKFYYSFDAGGIHFIMLGAYVDYNRTGAQYSWLKKDLQRVDRAVTPWVVASWHSPWYNSYSSHYQEFECMRQEMEGLLYQHRVDIVFSGHVHAYERMNRVFNYTLDPCGPVYIIIGDGGNIEKIDIDHADDPGKCPSPGDNHPEFGGLCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEDSVGDQIYIVRQPD 555          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRY-----------GKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSI---PAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPT L+GPFEPATR FD +LR+GS+++P+  PRL        PEQIALA SS  TS+W+SWVTG+AQ+G ++TPLDPS V SEV Y           G  SG Y  V +G + VYSQLYP+ GLLNYTSG +HHVR+ GL+P T+YYY+CGDSS+     +S E +FETLP  + + YP R+AVVGDLGLT N+++T++HL +NDPS++++VGD+TYANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNH+IEPQ  G  +TF SYL RFAVPSEESGS + FYYSF+AGG+HFIMLGAYVDYN TGAQY+WL+ DL ++DR VTPW VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NY LD CGPVYIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQIYIVRQP+
Sbjct:   36 IPTKLDGPFEPATRAFDRALRQGSDEVPITEPRLAPCARTPAPEQIALAASSDATSVWVSWVTGEAQVGSHLTPLDPSTVRSEVWYSERPSPTAAAAGDVSGHYPHVARGKAEVYSQLYPYPGLLNYTSGAIHHVRLRGLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHDIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWAVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPD 555          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKK-NVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGD 1296
            +  A   IPTTL+GPF+P TRRF+PSLRRGS+DLPMDHPRL+K NV+ +FPEQIALA+S+PTSMW+SWVTGDA +GK+V PLDPS + SEV YGKE G Y   KKG + VYSQLYP +GLLNYTSGI+HHV IDGL+P T+YYY+CGDSS+PAMSEE +FETLP+PS+  YPHRIA VGDLGLTSNT+TTIDHL++NDPS++++VGDLTYANQYRT GGKG  CFSC+FPDAPIRETYQPRWD WGRFMEPLTS+VP MVIEGNHEIEPQ SGITFKSY  RFAVP+ ESGS SN YYSFDAGGVHF+MLGAYVDYN TG QYAWLK+DL ++DR VTPWLVA  HPPWYNSYSSHYQEFECMRQEME LLYQY VDIVF+GHVHAYERMNR+YNY LD CGPVYIT+GDGGNIE+VDVDFADDPGKC S+ D
Sbjct:   15 LLAAAETIPTTLDGPFKPLTRRFEPSLRRGSDDLPMDHPRLRKRNVSSDFPEQIALALSTPTSMWVSWVTGDAIVGKDVKPLDPSSIASEVWYGKEKGNYMLKKKGNATVYSQLYPSDGLLNYTSGIIHHVLIDGLEPETRYYYRCGDSSVPAMSEEISFETLPLPSKDAYPHRIAFVGDLGLTSNTTTTIDHLMENDPSLVIIVGDLTYANQYRTIGGKGVPCFSCSFPDAPIRETYQPRWDAWGRFMEPLTSKVPTMVIEGNHEIEPQASGITFKSYSERFAVPASESGSNSNLYYSFDAGGVHFVMLGAYVDYNNTGLQYAWLKEDLSKVDRAVTPWLVATMHPPWYNSYSSHYQEFECMRQEMEELLYQYRVDIVFAGHVHAYERMNRIYNYTLDPCGPVYITIGDGGNIEKVDVDFADDPGKCHSSYD 447          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPS-AGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IP+TL+GPF P T   D SLR  + DLP   PR+++ V    PEQI+L++SS   S+W+SW+TG+ QIGK V PLDP+ + S V++G          KG S+VYSQLYPF+GLLNYTSGI+HHVRI GLKP T YYY+CGD S  AMS+ H F T+P+ S S+YP RIAVVGDLGLT NT+ TI HLI N P +IL++GD++YAN Y  T G  + C+SC+FP+ PI ETYQPRWD WGRFME LTS+VP+MVIEGNHEIE Q    TF++Y +RFA P  ESGS S  YYSF+AGG+HF+MLGAY+ Y+ +  QY WLK DL ++DR+VTPWLVA+WHPPWY+SY++HY+E ECM++ ME LLY YG DIVF+GHVHAYER NRVYNY LD CGPVYI +GDGGN E++ ++ ADDPGKCP       P  GG C  NF+       FCW++QP++SA RESSFGHGILE+ N T+ALWTW+RNQD+  E   GDQIYIVRQP+
Sbjct:   22 IPSTLDGPFVPVTVPLDTSLRGQAIDLPDTDPRVRRRVIGFEPEQISLSLSSDHDSIWVSWITGEFQIGKKVKPLDPTSINSVVQFGTLRHSLSHEAKGHSLVYSQLYPFDGLLNYTSGIIHHVRITGLKPSTIYYYRCGDPSRRAMSKIHHFRTMPVSSPSSYPGRIAVVGDLGLTYNTTDTISHLIHNSPDLILLIGDVSYANLY-LTNGTSSDCYSCSFPETPIHETYQPRWDYWGRFMENLTSKVPLMVIEGNHEIELQAENKTFEAYSSRFAFPFNESGSSSTLYYSFNAGGIHFVMLGAYIAYDKSAEQYEWLKKDLAKVDRSVTPWLVASWHPPWYSSYTAHYREAECMKEAMEELLYSYGTDIVFNGHVHAYERSNRVYNYELDPCGPVYIVIGDGGNREKMAIEHADDPGKCPEPLTTPDPVMGGFCAWNFT---PSDKFCWDRQPDYSALRESSFGHGILEMKNETWALWTWYRNQDSSSE--VGDQIYIVRQPD 520          

Query:   25 PTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVT-LNFPEQIALAIS-SPTSMWISWVTGDAQIG-KNVTPLDPSKVGSEVRYGKESGKYESVKK---GVSVVYSQLYPFE-GLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            P+TL+GP  P T   DP+L   + DLP   P   K ++    PEQI++++S S  S+WISWVTG+ QIG K+  PLDP+ V S V+Y +E     + K+   G S+VY+Q Y  E G +NYTSGI+HHV++ GLKP T Y Y+CGD S+ AMS+E+ F T+P  +   YPHRI V GDLGLT NTST + H++ N P +++++G  +YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS ESGS S  YYSF+AGG HFI+L +Y  Y+ +  QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNY LD+CGPVYIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV N T+ALW+W+RNQD Y      D I+IVRQPE
Sbjct:   27 PSTLDGPLNPVTAPLDPNLNPIAFDLPESDPSFVKPISEFLLPEQISVSLSYSFDSVWISWVTGEYQIGEKDSAPLDPNCVQSIVQY-REFDVRRTRKQNATGHSIVYNQQYSSENGFMNYTSGIIHHVQLTGLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESGSFSPLYYSFNAGGAHFIVLNSYTLYDNSSDQYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEVKNETHALWSWNRNQDLYY--LAADVIHIVRQPE 539          

Query:  148 PEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1479
            P+Q+ ++++    M ++++T D            +KV S V YGK+ GKY+    G    Y   +       Y SG +HHV+I  L+  T YYY+CG +       E +F+T P    ST+P   A+VGDLG T  T+ T+ H+   D  + L+ GDL+YA                        +T+QP WD +GR +EPL S+ P MV EGNHEIE  P +   TFKSY  R+ +P  ES S SN YYSFD  GVH +MLG+Y D++    QY WL+ DL ++DR  TPW+V   H PWYN+  +H  E E MR+ ME+LL+   VD+VFSGHVHAYER  RVYN   D CGP++IT+GDGGN E + + F   P                                      S FRESSFGHG L+V++   A W+WHRN D+
Sbjct:   47 PQQVHISLAGKDHMRVTFITED------------NKVESVVEYGKQPGKYDGKATGECTSYKYFF-------YKSGKIHHVKIGPLQANTTYYYRCGGNG-----PEFSFKTPP----STFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYA------------------------DTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPL-----------------------------------SEFRESSFGHGRLKVMDGKRAHWSWHRNNDS 405          

Query:   82 RRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFEC--MRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            R+G+    + HP  + + T  FP+Q+ +++  P  M ISW+T              S +   V YG  SGKYE    G S  Y  L      L Y SG ++ V I  LKP T YYYKCG    P+ ++E +F T P    S +P + AV GDLG +  + +T++H+ + D  + ++ GDL+YAN Y                        QP WD +GR ++PL S+ P MV  GNHE+E  P +    F +Y  R+ +P EESGS SN YYSF+  GVH IMLG+Y D+     QY WL+++L ++DR  TPW+VA  H PWYNS  +H  E E   M++ ME LLY+  VD+VF+GHVHAYER +RVY    D+CGPVYI +GDGGN+E +   + D                                     PE S FRE+SFGHG L V N+T+A W WHRN D
Sbjct:   24 RQGTRKNLVIHPTNEDDPT--FPDQVHISLVGPDKMRISWIT-------------QSSISPSVVYGTVSGKYEGSANGTSSSYHYL------LIYRSGQINDVVIGPLKPNTVYYYKCGG---PSSTQEFSFRTPP----SKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMY------------------------QPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYERFSRVYQDKFDKCGPVYINIGDGGNLEGLATKYRD-----------------------------------PNPEISLFREASFGHGQLVVENATHARWEWHRNDD 405          

Query:  109 DHPRLKKNVTLNFP---------EQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGIT-FKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYI 1515
            D+ R K   TL FP         EQ+ ++++    M ++WVT D       +P       S V YG   GKY  + +G S  YS +        Y SG +HH  I  L+  T YYY+CG        E   F     P+Q  +P   AV GDLG T  T +T+DH+ Q   ++ L+ GDL+YA+                          Q +WD +G  ++PL S  P MV +GNHE E     +  F S+ +R+ +P EESGS SN YYSF+  GVH IMLG+Y DY+    QY+WLK DL ++DR  TPWL+  +H PWYNS ++H  E + M  EME LLY  GVDIVF+GHVHAYER  RV N   D CGPV+IT+GDGGN E +   + D     PS                              PEWS FRE+SFGHG L++VNST+ALWTWHRN D   E +  D++++
Sbjct:   25 DYVRPKPRETLQFPWKQKSSSVPEQVHISLAGDKHMRVTWVTNDKS-----SP-------SFVEYGTSPGKYSYLGQGESTSYSYIM-------YRSGKIHHTVIGPLEADTVYYYRCG-------GEGPEFHLKTPPAQ--FPITFAVAGDLGQTGWTKSTLDHIDQCKYAVHLLPGDLSYADYM------------------------QHKWDTFGELVQPLASVRPWMVTQGNHEKESIPFIVDEFVSFNSRWKMPYEESGSNSNLYYSFEVAGVHAIMLGSYTDYDRYSDQYSWLKADLSKVDRERTPWLIVLFHVPWYNSNNAHQHEGDEMMAEMEPLLYASGVDIVFTGHVHAYERTKRVNNGKSDPCGPVHITIGDGGNREGLARKYKD-----PS------------------------------PEWSVFREASFGHGELQMVNSTHALWTWHRNDD--DEPTRSDEVWL 414          

Query:  145 FPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            +P+Q+ ++++    M +++ T D              V S V YGK   KY+    G S  Y+  +       Y SG +HHV+I  LKP TKYYY+CG        +E +F+T P    S +P   AV GDLG T  T  T+D + + D  + L+ GDL+YA                        +T+QP WD +GR +E L S  P MV EGNHEIE  P    I+FKSY  R+ +P  ES S SN YYSFD  GVH +MLG+Y  Y +   QY WL+ DL ++DR  TPWLV   H PWY++  +HY E E MR  +E+LLY+  VD+VF+GHVH YER   +YN   D CGP+YIT+GDGGN E + + F                                      Q   S FRESSFGHG L +++   A W+WHRN D
Sbjct:   50 YPQQVHISLAGKDHMRVTYTTDDLN------------VASMVEYGKHPKKYDKKTAGESTSYTYFF-------YNSGKIHHVKIGPLKPNTKYYYRCGGHG-----DEFSFKTPP----SKFPIEFAVAGDLGQTDWTVRTLDQIRKRDFDVFLLPGDLSYA------------------------DTHQPLWDSFGRLLETLASTRPWMVTEGNHEIESFPTNDHISFKSYNARWLMPHAESLSHSNLYYSFDVAGVHTVMLGSYTPYESHSDQYHWLQADLRKVDRKKTPWLVVVMHTPWYSTNKAHYGEGEKMRSALESLLYRAQVDVVFAGHVHTYERFKPIYNKKADPCGPMYITIGDGGNREGLALRFK-----------------------------------KPQSPLSEFRESSFGHGRLRIIDHKRAHWSWHRNND 408          

Query:   97 DLPMDHPRLKKNVTLNFPEQIALAISSPT--SMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQND--PSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY-----------MLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY 1482
            D+P+D    +     N P+Q+ +        +M +SWVT D          +P    S+V Y  E+ +++ V +G    Y+         NYTSG +HH  I  L+  TKYYY+ G  +    +    + T P       P+   ++GDLG + +++ T+ H  +N      +L VGDL+YA+ Y                  P  +    RWD WGRF+E  T+  P +   GNHEI+  P++     FK +  R+ VP + SGS   F+Y       + I+L +Y  Y     QY WL+++L +++RT TPWL+   H PWYNSY+ HY E E MR   E    Q+ VD+VF+GHVHAYER  RV N            + D+  PVYIT+GDGGN+E +  +  D                                    QPE+SAFRE+SFGH  L++ N T+A ++WHRNQD Y
Sbjct:   39 DMPLDSDVFRVPPGYNAPQQVHITQGDHVGKAMIVSWVTVD----------EPGS--SKVVYWSENSQHKKVARGNIRTYTYF-------NYTSGYIHHCTIRNLEYNTKYYYEVGIGN----TTRSFWFTTPPEVGPDVPYTFGLIGDLGQSFDSNRTLTHYERNPIKGQAVLFVGDLSYADNY------------------PNHDNV--RWDTWGRFVERSTAYQPWIWTAGNHEIDFAPEIGETKPFKPFTKRYHVPYKASGSTETFWYPIKRASAYIIVLSSYSAYGKYTPQYKWLEEELPKVNRTETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQHKVDLVFAGHVHAYERSERVSNVAYDIVNGKCTPVRDQSAPVYITIGDGGNLEGLATNMTDP-----------------------------------QPEYSAFREASFGHATLDIKNRTHAYYSWHRNQDGY 440          

Query:   91 SNDLPMDHPRLKKNVTLNFPEQIALAISSPT--SMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDH--LIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGIT-FKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY-----------MLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            + D+P+D    +     N P+Q+ +        +M ISWVT D          +P    S VRY  E    + + KG    Y          NY+SG +HH  I  LK  TKYYY+ G   +   +   +F T P       P+   ++GDLG + +++TT+ H  L       +L VGDL+YA++Y                  P  +    RWD WGRF E   +  P +   GNHEIE  P+++    FK +  R+ VP E S S S F+YS      H I+L +++ Y     QY WLK +L ++ R+ TPWL+   H P YNSY+ H+ E E MR + EA   +Y VD+VF+GHVHAYER  RV N            + D+  PVYIT+GD GN   +D +                                       QPE+SAFRE+SFGHG+ ++ N T+A ++W+RNQD
Sbjct:    8 NRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMD----------EPGS--SAVRYWSEKNGRKRIAKGKMSTYR-------FFNYSSGFIHHTTIRKLKYNTKYYYEVG---LRNTTRRFSFITPPQTGLDV-PYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRY------------------PNHDNV--RWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSHIAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITDGLCTPVKDQSAPVYITIGDAGNYGVIDSNMI-----------------------------------QPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQD 409          

Query:   97 DLPMDHPRLKKNVTLNFPEQIALAISSPT--SMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSM---ILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVS-GITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY-----------MLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIY 1512
            D+P+D    +     N P+Q+ +        ++ +SWVT +A            K  ++V Y KE+    S KK  +   +  Y F    NYTSG +HH  I  L+  TKYYY  G       +E   +   P       P+   ++GDLG + +++ T+ H  +N+P+    +L VGD++YA+ Y               PD   R     RWD WGRF E  T+  P +   GNHE++  P++     FK +  R+  P   SGS   F+YS   G  + I+L +Y  Y     QY WL+++  +++RT TPWL+   H PWYNSY  HY E E MR   EA   +Y VD+VF+GHVHAYER  RV N            + D+  PVYIT+GDGGNIE +     +                                    QP++SAFRE+SFGH I  + N T+A + WHRN D Y  +  GD+++
Sbjct:   42 DMPLDSDVFRVPCGYNAPQQVHITQGDVEGKAVIVSWVTQEA------------KGSNKVIYWKEN----STKKHKAHGKTNTYKF---YNYTSGFIHHCPIRNLEYDTKYYYVLG----VGQTERKFWFFTPPEIGPDVPYTFGLIGDLGQSYDSNITLTHY-ENNPTKGQAVLFVGDISYADTY---------------PDHDNR-----RWDSWGRFAERSTAYQPWIWTTGNHELDFAPEIGENRPFKPFTHRYRTPYRSSGSTEPFWYSIKRGPAYIIVLASYSAYGKYTPQYQWLEEEFPKVNRTETPWLIVLMHSPWYNSYDYHYMEGETMRVMYEAWFVKYKVDVVFAGHVHAYERSERVSNIAYNVVNGICTPVKDQSAPVYITIGDGGNIEGLATKMTE-----------------------------------PQPKYSAFREASFGHAIFSIKNRTHAHYGWHRNHDGYAVE--GDRMW 451          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKK-NVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGD 1296
            +  A   IPTTL+GPF+P TRRF+PSLRRGS+DLPMDHPRL+K NV+ +FPEQIALA+S+PTSMW+SWVTGDA +GK+V PLDPS + SEV YGKE G Y   KKG + VYSQLYP +GLLNYTSGI+HHV IDGL+P T+YYY+CGDSS+PAMSEE +FETLP+PS+  YPHRIA VGDLGLTSNT+TTIDHL++NDPS++++VGDLTYANQYRT GGKG  CFSC+FPDAPIRETYQPRWD WGRFMEPLTS+VP MVIEGNHEIEPQ SGITFKSY  RFAVP+ ESGS SNFYYSFDAGGVHF+MLGAYVDYN TG QYAWLK+DL ++DR VTPWLVA  HPPWYNSYSSHYQEFECMRQEME LLYQY VDIVF+GHVHAYERMNR+YNY LD CGPVYIT+GDGGNIE+VDVDFADDPGKC S+ D
Sbjct:   15 LLAAAETIPTTLDGPFKPLTRRFEPSLRRGSDDLPMDHPRLRKRNVSSDFPEQIALALSTPTSMWVSWVTGDAIVGKDVKPLDPSSIASEVWYGKEKGNYMLKKKGNATVYSQLYPSDGLLNYTSGIIHHVLIDGLEPETRYYYRCGDSSVPAMSEEISFETLPLPSKDAYPHRIAFVGDLGLTSNTTTTIDHLMENDPSLVIIVGDLTYANQYRTIGGKGVPCFSCSFPDAPIRETYQPRWDAWGRFMEPLTSKVPTMVIEGNHEIEPQASGITFKSYSERFAVPASESGSNSNFYYSFDAGGVHFVMLGAYVDYNNTGLQYAWLKEDLSKVDRAVTPWLVATMHPPWYNSYSSHYQEFECMRQEMEELLYQYRVDIVFAGHVHAYERMNRIYNYTLDPCGPVYITIGDGGNIEKVDVDFADDPGKCHSSYD 447          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPS-AGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IP+TL+GPF P T   D SLR  + DLP   PR+++ V    PEQI+L++SS   S+W+SW+TG+ QIGK V PLDP+ + S V++G          KG S+VYSQLYPF+GLLNYTSGI+HHVRI GLKP T YYY+CGD S  AMS+ H F T+P+ S S+YP RIAVVGDLGLT NT+ TI HLI N P +IL++GD++YAN Y  T G  + C+SC+FP+ PI ETYQPRWD WGRFME LTS+VP+MVIEGNHEIE Q    TF++Y +RFA P  ESGS S  YYSF+AGG+HF+MLGAY+ Y+ +  QY WLK DL ++DR+VTPWLVA+WHPPWY+SY++HY+E ECM++ ME LLY YG DIVF+GHVHAYER NRVYNY LD CGPVYI +GDGGN E++ ++ ADDPGKCP       P  GG C  NF+       FCW++QP++SA RESSFGHGILE+ N T+ALWTW+RNQD+  E   GDQIYIVRQP+
Sbjct:   22 IPSTLDGPFVPVTVPLDTSLRGQAIDLPDTDPRVRRRVIGFEPEQISLSLSSDHDSIWVSWITGEFQIGKKVKPLDPTSINSVVQFGTLRHSLSHEAKGHSLVYSQLYPFDGLLNYTSGIIHHVRITGLKPSTIYYYRCGDPSRRAMSKIHHFRTMPVSSPSSYPGRIAVVGDLGLTYNTTDTISHLIHNSPDLILLIGDVSYANLY-LTNGTSSDCYSCSFPETPIHETYQPRWDYWGRFMENLTSKVPLMVIEGNHEIELQAENKTFEAYSSRFAFPFNESGSSSTLYYSFNAGGIHFVMLGAYIAYDKSAEQYEWLKKDLAKVDRSVTPWLVASWHPPWYSSYTAHYREAECMKEAMEELLYSYGTDIVFNGHVHAYERSNRVYNYELDPCGPVYIVIGDGGNREKMAIEHADDPGKCPEPLTTPDPVMGGFCAWNFT---PSDKFCWDRQPDYSALRESSFGHGILEMKNETWALWTWYRNQDSSSE--VGDQIYIVRQPD 520          

Query:   25 PTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVT-LNFPEQIALAIS-SPTSMWISWVTGDAQIG-KNVTPLDPSKVGSEVRYGKESGKYESVKK---GVSVVYSQLYPFE-GLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            P+TL+GP  P T   DP+L   + DLP   P   K ++    PEQI++++S S  S+WISWVTG+ QIG K+  PLDP+ V S V+Y +E     + K+   G S+VY+Q Y  E G +NYTSGI+HHV++ GLKP T Y Y+CGD S+ AMS+E+ F T+P  +   YPHRI V GDLGLT NTST + H++ N P +++++G  +YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS ESGS S  YYSF+AGG HFI+L +Y  Y+ +  QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNY LD+CGPVYIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV N T+ALW+W+RNQD Y      D I+IVRQPE
Sbjct:   27 PSTLDGPLNPVTAPLDPNLNPIAFDLPESDPSFVKPISEFLLPEQISVSLSYSFDSVWISWVTGEYQIGEKDSAPLDPNCVQSIVQY-REFDVRRTRKQNATGHSIVYNQQYSSENGFMNYTSGIIHHVQLTGLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESGSFSPLYYSFNAGGAHFIVLNSYTLYDNSSDQYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEVKNETHALWSWNRNQDLYY--LAADVIHIVRQPE 539          

Query:   25 PTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVT-LNFPEQIALAIS-SPTSMWISWVTGDAQIG-KNVTPLDPSKVGSEVRYGKESGKYESVKK---GVSVVYSQLYPFE-GLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            P+TL+GP  P T   DP+L   + DLP   P   K ++    PEQI++++S S  S+WISWVTG+ QIG K+  PLDP+ V S V+Y +E     + K+   G S+VY+Q Y  E G +NYTSGI+HHV++ GLKP T Y Y+CGD S+ AMS+E+ F T+P  +   YPHRI V GDLGLT NTST + H++ N P +++++G  +YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS ES                               QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNY LD+CGPVYIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV N T+ALW+W+RNQD Y      D I+IVRQPE
Sbjct:   27 PSTLDGPLNPVTAPLDPNLNPIAFDLPESDPSFVKPISEFLLPEQISVSLSYSFDSVWISWVTGEYQIGEKDSAPLDPNCVQSIVQY-REFDVRRTRKQNATGHSIVYNQQYSSENGFMNYTSGIIHHVQLTGLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESAD-----------------------------QYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEVKNETHALWSWNRNQDLYY--LAADVIHIVRQPE 510          

Query:  193 ISWVTGDAQIG-KNVTPLDPSKVGSEVRYGKESGKYESVKK---GVSVVYSQLYPFE-GLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTT-------------GGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV-SGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDN-TPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEV 1431
            + + TG+ QIG K+  PLDP+ V S V+Y +E     + K+   G S+VY+Q Y  E G +NYTSGI+HHV++ GLKP T Y Y+CGD S+ AMS+E+ F T+P  +   YPHRI V GDLGLT NTST + H++ N P +++++G  +YA+ Y                 G  + C SC        ETYQPRWD WGRFMEPLT+ VP M++ G HEIEPQ  + +TF +Y +RFA PS ESGS S  YYSF+AGG HFI+L +Y  Y+ +  QY WL+ DL +++R+ TPW+VA W  PWY+++  HY+E E MR  +E LLY Y VDIVF+ HV AYER NRVYNY LD+CGPVYIT G GG   +++    DDPG  P    N +    G   LN +  P K   C  KQPE+SA+RESSFG GILEV
Sbjct:    4 VLYTTGEYQIGEKDSAPLDPNCVQSIVQY-REFDVRRTRKQNATGHSIVYNQQYSSENGFMNYTSGIIHHVQLTGLKPNTLYRYQCGDPSLSAMSKEYYFRTMPKSTSENYPHRIVVAGDLGLTYNTSTVLGHILSNHPDLVVLLGGFSYADTYLANKTKLDCSSCHCDQNGTSSDCGSCYSSG----ETYQPRWDYWGRFMEPLTANVPTMMVAGEHEIEPQTENNLTFAAYSSRFAFPSNESGSFSPLYYSFNAGGAHFIVLNSYTLYDNSSDQYIWLESDLIKINRSETPWVVATWSLPWYSTFKGHYREAESMRIHLEDLLYNYRVDIVFNSHVDAYERSNRVYNYTLDQCGPVYITTGAGG-AGKLETQHVDDPGNIPDPSQNYSCRSSG---LNSTLEPVKDETCPVKQPEYSAYRESSFGFGILEV 427          

Query:  148 PEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1479
            P+Q+ ++++    M ++++T D            +KV S V YGK+ GKY+    G    Y   +       Y SG +HHV+I  L+  T YYY+CG +       E +F+T P    ST+P   A+VGDLG T  T+ T+ H+   D  + L+ GDL+YA                        +T+QP WD +GR +EPL S+ P MV EGNHEIE  P +   TFKSY  R+ +P  ES S SN YYSFD  GVH +MLG+Y D++    QY WL+ DL ++DR  TPW+V   H PWYN+  +H  E E MR+ ME+LL+   VD+VFSGHVHAYER  RVYN   D CGP++IT+GDGGN E + + F   P                                      S FRESSFGHG L+V++   A W+WHRN D+
Sbjct:   47 PQQVHISLAGKDHMRVTFITED------------NKVESVVEYGKQPGKYDGKATGECTSYKYFF-------YKSGKIHHVKIGPLQANTTYYYRCGGNG-----PEFSFKTPP----STFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYA------------------------DTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPL-----------------------------------SEFRESSFGHGRLKVMDGKRAHWSWHRNNDS 405          

Query:   82 RRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFEC--MRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            R+G+    + HP  + + T  FP+Q+ +++  P  M ISW+T              S +   V YG  SGKYE    G S  Y  L      L Y SG ++ V I  LKP T YYYKCG    P+ ++E +F T P    S +P + AV GDLG +  + +T++H+ + D  + ++ GDL+YAN Y                        QP WD +GR ++PL S+ P MV  GNHE+E  P +    F +Y  R+ +P EESGS SN YYSF+  GVH IMLG+Y D+     QY WL+++L ++DR  TPW+VA  H PWYNS  +H  E E   M++ ME LLY+  VD+VF+GHVHAYER +RVY    D+CGPVYI +GDGGN+E +   + D                                     PE S FRE+SFGHG L V N+T+A W WHRN D
Sbjct:   24 RQGTRKNLVIHPTNEDDPT--FPDQVHISLVGPDKMRISWIT-------------QSSISPSVVYGTVSGKYEGSANGTSSSYHYL------LIYRSGQINDVVIGPLKPNTVYYYKCGG---PSSTQEFSFRTPP----SKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMY------------------------QPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYERFSRVYQDKFDKCGPVYINIGDGGNLEGLATKYRD-----------------------------------PNPEISLFREASFGHGQLVVENATHARWEWHRNDD 405          

Query:  109 DHPRLKKNVTLNFP---------EQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGIT-FKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYI 1515
            D+ R K   TL FP         EQ+ ++++    M ++WVT D       +P       S V YG   GKY  + +G S  YS +        Y SG +HH  I  L+  T YYY+CG        E   F     P+Q  +P   AV GDLG T  T +T+DH+ Q   ++ L+ GDL+YA+                          Q +WD +G  ++PL S  P MV +GNHE E     +  F S+ +R+ +P EESGS SN YYSF+  GVH IMLG+Y DY+    QY+WLK DL ++DR  TPWL+  +H PWYNS ++H  E + M  EME LLY  GVDIVF+GHVHAYER  RV N   D CGPV+IT+GDGGN E +   + D     PS                              PEWS FRE+SFGHG L++VNST+ALWTWHRN D   E +  D++++
Sbjct:   25 DYVRPKPRETLQFPWKQKSSSVPEQVHISLAGDKHMRVTWVTNDKS-----SP-------SFVEYGTSPGKYSYLGQGESTSYSYIM-------YRSGKIHHTVIGPLEADTVYYYRCG-------GEGPEFHLKTPPAQ--FPITFAVAGDLGQTGWTKSTLDHIDQCKYAVHLLPGDLSYADYM------------------------QHKWDTFGELVQPLASVRPWMVTQGNHEKESIPFIVDEFVSFNSRWKMPYEESGSNSNLYYSFEVAGVHAIMLGSYTDYDRYSDQYSWLKADLSKVDRERTPWLIVLFHVPWYNSNNAHQHEGDEMMAEMEPLLYASGVDIVFTGHVHAYERTKRVNNGKSDPCGPVHITIGDGGNREGLARKYKD-----PS------------------------------PEWSVFREASFGHGELQMVNSTHALWTWHRNDD--DEPTRSDEVWL 414          

Query:  145 FPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 1476
            +P+Q+ ++++    M +++ T D              V S V YGK   KY+    G S  Y+  +       Y SG +HHV+I  LKP TKYYY+CG        +E +F+T P    S +P   AV GDLG T  T  T+D + + D  + L+ GDL+YA                        +T+QP WD +GR +E L S  P MV EGNHEIE  P    I+FKSY  R+ +P  ES S SN YYSFD  GVH +MLG+Y  Y +   QY WL+ DL ++DR  TPWLV   H PWY++  +HY E E MR  +E+LLY+  VD+VF+GHVH YER   +YN   D CGP+YIT+GDGGN E + + F                                      Q   S FRESSFGHG L +++   A W+WHRN D
Sbjct:   50 YPQQVHISLAGKDHMRVTYTTDDLN------------VASMVEYGKHPKKYDKKTAGESTSYTYFF-------YNSGKIHHVKIGPLKPNTKYYYRCGGHG-----DEFSFKTPP----SKFPIEFAVAGDLGQTDWTVRTLDQIRKRDFDVFLLPGDLSYA------------------------DTHQPLWDSFGRLLETLASTRPWMVTEGNHEIESFPTNDHISFKSYNARWLMPHAESLSHSNLYYSFDVAGVHTVMLGSYTPYESHSDQYHWLQADLRKVDRKKTPWLVVVMHTPWYSTNKAHYGEGEKMRSALESLLYRAQVDVVFAGHVHTYERFKPIYNKKADPCGPMYITIGDGGNREGLALRFK-----------------------------------KPQSPLSEFRESSFGHGRLRIIDHKRAHWSWHRNND 408          

Query:   82 RRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFEC--MRQEMEALLYQYGVDIVFSGHVHAYER 1164
            R+G+    + HP  + + T  FP+Q+ +++  P  M ISW+T              S +   V YG  SGKYE    G S  Y  L      L Y SG ++ V I  LKP T YYYKCG    P+ ++E +F T P    S +P + AV GDLG +  + +T++H+ + D  + ++ GDL+YAN Y                        QP WD +GR ++PL S+ P MV  GNHE+E  P +    F +Y  R+ +P EESGS SN YYSF+  GVH IMLG+Y D+     QY WL+++L ++DR  TPW+VA  H PWYNS  +H  E E   M++ ME LLY+  VD+VF+GHVHAYER
Sbjct:   24 RQGTRKNLVIHPTNEDDPT--FPDQVHISLVGPDKMRISWIT-------------QSSISPSVVYGTVSGKYEGSANGTSSSYHYL------LIYRSGQINDVVIGPLKPNTVYYYKCGG---PSSTQEFSFRTPP----SKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMY------------------------QPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYER 336          

Query:    7 VAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            +AQ+ IPTTL+GPF+P TRRFDPSLRRGS+DLPM+HPRLKKN T NFPEQI+LAISSPTSMW+SWVTG+AQIG +V PLDP+ V SEV YGKESGKY S  KG S VY+QLYPFEGL NYTSGI+HHVRIDGL+P TKY+YKCGDSSIPAMSEEH FETLP+PS + YPHRIA++GDLGLTSN+STTIDH+I NDPSMILMVGDLTYANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITFKSYLTR+AVPSEESGS SNFYYSFDAGG+HF+MLGAYVDYN+TGAQY+WLK DL+Q+DR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQIY+VRQPE
Sbjct:   24 LAQNQIPTTLDGPFKPVTRRFDPSLRRGSDDLPMNHPRLKKNATSNFPEQISLAISSPTSMWVSWVTGEAQIGSDVIPLDPASVASEVWYGKESGKYASRGKGNSTVYTQLYPFEGLSNYTSGIIHHVRIDGLEPETKYFYKCGDSSIPAMSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPE 531          

Query:  457 MSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            MSEEH FETLP+PS + YPHRIA++GDLGLTSN+STTIDH+I NDPSMILMVGDLTYANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITFKSYLTR+AVPSEESGS SNFYYSFDAGG+HF+MLGAYVDYN+TGAQY+WLK DL+Q+DR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQIY+VRQPE
Sbjct:    1 MSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPE 358          

Query:    7 VAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIG---KNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPE--FGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            +  + IP+TL+GPFEP T  FD SLR  + DLP   PR+++ V    PEQI+L++S+   S+WISW+TG+ Q+    KN+TPLDP  V S VRYG          KG S+VYSQLYPFEGL NYTSGI+HHVR+ GLKP   YYY+CGD SI A+S+ ++F+T+P+ S  TYP RIAV+GDLGLT NTSTTI H+I N P + L+VGD+TYAN Y  T G G  C+SC+FP++PI ETYQPRWD WGRFM+PL S+VP+MV+EGNHEIE QV   TF +Y +RFA P++ESGS S FYYSF+AGG+HF+MLGAY+ Y+ +  QY WL+ DL  +DR VTPWLVA WHPPWY+SY++HY+E ECM   ME LLY Y VDIVF+GHVHAYER NRVYNY LD CGPV+I VGDGGN E++ V  AD+PG CP     TP+   GG C LNF++GPA G FCW++QP++SAFRESSFGHGILEV N T+ALWTWHRNQD+    + GDQIYIVRQP+
Sbjct:   30 IRSNVIPSTLDGPFEPRTVPFDVSLRGNAVDLPDADPRVRRRVKGFQPEQISLSLSATYDSVWISWITGEFQMSNHNKNITPLDPKSVASVVRYGTLRNPLNHEAKGYSLVYSQLYPFEGLQNYTSGIIHHVRLTGLKPDKLYYYRCGDPSIGALSDVYSFKTMPVSSPKTYPKRIAVMGDLGLTYNTSTTISHVISNKPQLALLVGDVTYANLY-LTNGTGCDCYSCSFPNSPIHETYQPRWDYWGRFMQPLVSKVPLMVVEGNHEIEKQVGNQTFAAYSSRFAFPAKESGSSSTFYYSFNAGGIHFVMLGAYIAYHRSSDQYRWLERDLANVDRFVTPWLVAVWHPPWYSSYNAHYREAECMMAAMEELLYSYAVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIVVGDGGNREKMAVGHADEPGNCPDPA-TTPDQHIGGFCALNFTTGPAAGQFCWDRQPDYSAFRESSFGHGILEVKNQTWALWTWHRNQDS--RSTVGDQIYIVRQPD 539          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEF-GGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF+P T   D + R  + DLP   PR+++ V    PEQI++++S+   S+WISW+TGD QIG  + PL+P  V S VRYG+          G S+VY+QLYPF GL NYTSGI+HHVR+ GLKP T Y+Y+CGD SIPAMS ++ F+T+P     +YP RIA+VGDLGLT NT++T+DH+I N+P +IL+VGD+ YAN Y  T G GA C+SC+F   PI ETYQPRWD WGR+M+P+TS++P+MV+EGNHEIE QV   TF +Y +RFA PS+ESGS S FYYSF+AGG+HFIMLG Y+ YN +  QY WLK DL ++DR VTPWLVA WHPPWY++Y +HY+E ECMR  ME LLYQYGVDI+F+GH+HAYER NRVYNY LD CGPV+ITVGDGGN E++ +  AD+P  CP       E+ GG C  NF+SGPA G FCW++QP++SA+RESSFGHGI EV N T+ALWTWHRNQD Y  +S GDQIYIVRQPE
Sbjct:   28 IPTTLDGPFKPVTVPLDKTFRGHAVDLPDTDPRVQRVVQGFEPEQISVSLSTTHDSVWISWITGDFQIGDRIKPLNPKTVASVVRYGRLRIPLIHKATGYSLVYNQLYPFVGLQNYTSGIIHHVRLTGLKPNTLYHYQCGDPSIPAMSSKYYFKTMPASGPKSYPSRIAIVGDLGLTYNTTSTVDHVIGNNPDLILLVGDVCYANLY-LTNGTGADCYSCSFSQTPIHETYQPRWDYWGRYMQPVTSKIPIMVVEGNHEIEKQVENQTFVAYSSRFAFPSKESGSSSTFYYSFNAGGIHFIMLGGYIAYNKSAHQYKWLKKDLAKVDRKVTPWLVATWHPPWYSTYKAHYREAECMRTAMEDLLYQYGVDIIFNGHIHAYERSNRVYNYTLDPCGPVHITVGDGGNREKMAIAHADEPRNCPDPSTTPDEYMGGFCAFNFTSGPAAGKFCWDRQPDYSAYRESSFGHGIFEVKNETHALWTWHRNQDMY--NSPGDQIYIVRQPE 529          

Query:    7 VAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGD-------------------AQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPE--FGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            +  + IP+TL+GPFEP T  FD SLR  + DLP   PR+++ V    PEQI+L++S+   S+WISW+TG                    +   KN+TPLDP  V S VRYG          KG S+VYSQLYPFEGL NYTSGI+HHVR+ GLKP   YYY+CGD SI A+S+ ++F+T+P+ S  TYP RIAV+GDLGLT NTSTTI H+I N P + L+VGD+TYAN Y  T G G  C+SC+FP++PI ETYQPRWD WGRFM+PL S+VP+MV+EGNHEIE QV   TF +Y +RFA P++ESGS S FYYSF+AGG+HF+MLGAY+ Y+ +  QY WL+ DL  +DR VTPWLVA WHPPWY+SY++HY+E ECM   ME LLY Y VDIVF+GHVHAYER NRVYNY LD CGPV+I VGDGGN E++ V  AD+PG CP     TP+   GG C LNF++GPA G FCW++QP++SAFRESSFGHGILEV N T+ALWTWHRNQD+    + GDQIYIVRQP+
Sbjct:   30 IRSNVIPSTLDGPFEPRTVPFDVSLRGNAVDLPDADPRVRRRVKGFQPEQISLSLSATYDSVWISWITGTGGRCDQVFFSMFFTGEFQMSNHNKNITPLDPKSVASVVRYGTLRNPLNHEAKGYSLVYSQLYPFEGLQNYTSGIIHHVRLTGLKPDKLYYYRCGDPSIGALSDVYSFKTMPVSSPKTYPKRIAVMGDLGLTYNTSTTISHVISNKPQLALLVGDVTYANLY-LTNGTGCDCYSCSFPNSPIHETYQPRWDYWGRFMQPLVSKVPLMVVEGNHEIEKQVGNQTFAAYSSRFAFPAKESGSSSTFYYSFNAGGIHFVMLGAYIAYHRSSDQYRWLERDLANVDRFVTPWLVAVWHPPWYSSYNAHYREAECMMAAMEELLYSYAVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIVVGDGGNREKMAVGHADEPGNCPDPA-TTPDQHIGGFCALNFTTGPAAGQFCWDRQPDYSAFRESSFGHGILEVKNQTWALWTWHRNQDS--RSTVGDQIYIVRQPD 555          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSN-DLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKC--PSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            + +      TTLEGPF+P T  FD     G+  DLP   P++++ V    PEQ+++++SS   S+WISW+TGD+QIG ++TPLDP  V S V YG E  +    + G S VY+QLYPFEGL NYTSGI+HHVR+ GL+P T Y Y+CGD  I AMS+   F T+P  S + YP R+AVVGDLGLT NTSTT  HL+ N P ++++VG ++YA+ Y  T G G+ C+ C+F ++PI ETYQPRWD WGRFM+PL + VP M++ G HEIEPQ     F SY +RF  PSEESGS S+ YYSF+AGG+HF++L  Y  Y+ +  QY WL+ DL+ ++R VTPWLVA W+PPWY+++ + Y+E ECMR EME LLY++GVDIVF+GHVHAYER NRVYNY LD CGPVYIT+GDGG+ E + V  ADDP +C  PS   +    GG C  NF+SGPA                E        +V N T+ALW+WHRN+D Y  ++ GD +YIVR+P+
Sbjct:   19 LIIVNGNFSTTLEGPFKPVTVPFDNKTYHGNAIDLPDTDPQVQRTVQGFEPEQVSVSLSSDYDSVWISWITGDSQIGGDITPLDPESVYSVVHYGIEGSQMSYEEVGYSFVYNQLYPFEGLQNYTSGIIHHVRLTGLEPSTLYQYQCGDPYISAMSDVFYFRTMPPSSPTNYPRRVAVVGDLGLTYNTSTTFSHLLSNHPDLLVLVGGISYADMY-LTNGTGSDCYPCSFDESPIHETYQPRWDYWGRFMQPLVANVPTMLVGGKHEIEPQAEDQIFVSYSSRFVFPSEESGSSSSVYYSFNAGGIHFVILNPYTYYDKSSDQYKWLEGDLYNVNRNVTPWLVAVWYPPWYSTFKAQYREAECMRVEMEDLLYEHGVDIVFNGHVHAYERSNRVYNYSLDPCGPVYITIGDGGSREDIAVTHADDPDECPEPSTTADLDIGGGFCGFNFTSGPA---------------AEHKLMGCSFQVKNVTHALWSWHRNRDYY--ETAGDILYIVREPD 514          

Query:  187 MWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1479
            M ++W+T D                S V YGK+ G Y ++  G    Y   +       Y+SG +HHV+I  L+PGT YYY+CG S       E +F+T P    +T P    V+GDLG T  T++T+ H+   D  ++L+ GDL+YA                        +T QP WD +GR +E   S+ P MV EGNHE E  P +    FK+Y  R+ +P EES S SN YYSF+  G H IMLG+Y D++    QY WL+ DL  +DR  TPW++   H PWYN+ ++H  E E MR+ ME LLY+  VD+VF+GHVHAYER  R+Y+  +D CGPVYIT+GDGGN E + + F                                    N     S +RE+SFGHG L +++ T A W+WHRN D+
Sbjct:    1 MRVTWITDDKH------------APSTVEYGKQPGTYNAMATGDHTSYRYFF-------YSSGKIHHVKIGPLEPGTTYYYRCGGSG-----PELSFKTPP----ATLPLEFVVIGDLGQTGWTNSTLAHVNSRDYDVLLLPGDLSYA------------------------DTNQPLWDSFGRLVEKYASQRPWMVTEGNHETEIFPIIQPHGFKAYNARWLMPYEESNSSSNLYYSFNVVGTHVIMLGSYTDFDEHSQQYKWLEADLGSIDRKKTPWVIVLLHAPWYNTNNAHQGEGESMRKAMEELLYKARVDVVFAGHVHAYERFARIYDNKVDPCGPVYITIGDGGNREGLALTFQ-----------------------------------NPASPLSLYREASFGHGRLRIMDETRAHWSWHRNNDS 346          

Query:  148 PEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEP-QVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYI 1515
            P+Q+ ++++    M +SWV+ D    K+  P+        V YG   G+Y +  +G S  YS L+       Y+SG +HH  I  L+  T YYY+CG         E+  +T P    + +P   AV GDLG T  T +T+DH+      + L+ GDL+YA+                          Q RWD +G  +EPL S  P MV +GNHE E        F+SY +R+ +P EESGS SN YYSF+  G H IMLG+Y DY+    QY WLK D+ ++DR  TPWL+  +H PWYNS  +H  E + M   ME LL+   VDIV +GHVHAYER  RV    LD CG V+IT+GDGGN E +   +                                    N QP WS FRE+SFGHG L++ NST+A W+WHRN D   E    DQ++I
Sbjct:   42 PQQVHISLAGDKHMRVSWVSND----KSTLPM--------VEYGTSPGRYSNKSQGESTSYSYLF-------YSSGKIHHTIIGPLEDNTVYYYRCGGGG-----PEYKLKTPP----AQFPVMFAVAGDLGQTGWTKSTLDHIDLCKYDVHLLPGDLSYADYI------------------------QHRWDTFGELVEPLASARPWMVTQGNHEKESIMFFKDGFQSYNSRWKMPYEESGSSSNLYYSFEVAGAHIIMLGSYTDYDEHSDQYNWLKADVAKVDRKKTPWLIVLFHVPWYNSNEAHQDEGDRMLAAMEPLLHAASVDIVLAGHVHAYERTERVNKGKLDPCGAVHITIGDGGNREGLASKYK-----------------------------------NPQPAWSVFREASFGHGELKLANSTHAYWSWHRNDD--DESVRSDQVWI 409          

Query:   55 ATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYI 1515
            A+    PS R+      +D  R  K+ +   P+Q+ ++++    M +SWVT D                S V YG   G+Y ++  G S  YS L+       Y+SG +HH  I  L+    YYY+CG         E+  +T P    + +P   AV GDLG T  T +T+DH+ Q    + L+ GDL+YA+                          Q  WD +G  +EPL S  P MV +GNHE E  P +    F+ Y +R+ +P EESGS SN YYSF+  G H IMLG+Y  Y+    QY WL+ DL ++DR  TPWL+  +H PWYNS  +H  E + M + ME LLY   VDIV +GHVHAYER  RV N  LD CG V+IT+GDGGN E                        G+ H              N QP WS FRE+SFGHG L++ NST+A W+WHRN D   E    DQ++I
Sbjct:   18 ASEYIRPSTRKN-----LDFSRPSKSSS--HPQQVHISLAGDKHMRVSWVTDD------------KSAASMVEYGTSPGRYSNIALGESTWYSYLF-------YSSGKIHHTVIGPLEDNAVYYYRCGGGG-----PEYKLKTPP----AQFPVTFAVAGDLGQTGWTQSTLDHIDQCKYDVHLLPGDLSYADYM------------------------QHLWDTFGELVEPLASARPWMVTQGNHERESIPFLKD-GFEPYNSRWKMPFEESGSSSNLYYSFEVSGAHIIMLGSYTGYDEYSNQYNWLEADLAKVDRNKTPWLLVLFHVPWYNSNEAHQNEGDRMMEAMEPLLYAASVDIVLAGHVHAYERTERVNNGKLDPCGAVHITIGDGGNRE------------------------GLAHK-----------YKNPQPAWSVFREASFGHGELKLANSTHAFWSWHRNDD--DEPVRSDQVWI 409          

Query:   91 SNDLPMDHPRLKKNVTLNFPEQIALAIS--SPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSG-ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY-----------MLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYK 1485
            S D+P+D+         N P+Q+ +     +  ++ ISWVT D + G N           +V+YG    KY+   +G    Y+         NY SG +H   +DGL+  TKYYYK G       S E  F+T P  +  T P++  ++GDLG T N+ +T++H +Q+    +L VGDL YA++Y+             + D  IR      WD WGRF+E   +  P M   GNHEIE  P +   I FKSYL R+  P   S S S F+Y+      H I+L +Y  +     Q+ WL+++L ++DR  TPWL+   H P YNS  +H+ E E MR   E    +Y VD+VF+GHVHAYER  RV N              D   PVYITVGDGGN E +   F D                                    QP++SAFRE+S+GH  LE+ N T+A++ W+RN D  K
Sbjct:   43 SIDIPLDNEVFAVPKGYNAPQQVHITQGDYNGKAVIISWVTPD-EPGTN-----------KVQYGVSKKKYDFTAEGTVKNYT-------FYNYKSGYIHQCLVDGLEYETKYYYKIGSGD---SSREFWFQTPPKINPDT-PYKFGIIGDLGQTYNSLSTLEHYMQSGAQAVLFVGDLAYADRYK-------------YNDVGIR------WDSWGRFVERSAAYQPWMWSAGNHEIEYMPYMGEVIPFKSYLNRYPTPHLASKSSSPFWYAIRRASAHIIVLSSYSSFVKYTPQWEWLREELKRVDREKTPWLIVLMHIPIYNSNEAHFMEGESMRAVFEKWFVRYKVDVVFAGHVHAYERSYRVSNIHYNVSSGDRFPAADESAPVYITVGDGGNQEGLAGRFRDP-----------------------------------QPDYSAFREASYGHSTLEIKNRTHAIYHWNRNDDGKK 446          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            +A+ QSPIPTTLEGPF PATRRFDPSLRRGS+DLPMDHPRLKK VT NFPEQIALAISSPT+MW+SWVTGDAQIGK V PLDPS VGSEVRYG+ESGKY SVKKGVSVVYSQLYPF GLLNYTS I+HHVRIDGLKPGTKYYYKCGDSSIPAMS+EHA ETLP P ++TYP RIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDL YANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYNATGAQYAWLKDDLH++DRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGP+YITVGDGGNIE+VDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKG+FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQ+YIVRQPE
Sbjct:   60 VALTQSPIPTTLEGPFVPATRRFDPSLRRGSDDLPMDHPRLKKKVTSNFPEQIALAISSPTAMWVSWVTGDAQIGKTVRPLDPSTVGSEVRYGEESGKYTSVKKGVSVVYSQLYPFAGLLNYTSAIIHHVRIDGLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGENTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPE 569          

Query:  361 NYTSGIVHHVRID-GLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            N    +V +V  D GLKPGTKYYYKCGDSSIPAMS+EHA ETLP P  +TYP RIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDL YANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITF+SYLTRFAVPSEE GSKSNFYYSFDAGGVHFIMLGAY+DYNATGAQYAWLKDDLH++DRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGP+YITVGDGGNIE+VDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKG+FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQ+YIVRQPE
Sbjct:  150 NANVNLVENVENDHGLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQVYIVRQPE 540          

Query:   13 QSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPE----FGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            ++ IPTTL+GPFEP T  FDPSLR  + DLP D  R+++ V    PEQI++++S+   S+WISW+TG+ QIG  + PLDP  V S VRYGK          G S+VY+QLYPFEGL NYTSGI+HHVR+ GLKP T Y+Y+CGD SIPAMS+ H + T+P+    +YP RIAVVGDLGLT NT+TTI HL  N+P ++L++GD+TYAN Y  T G G+ C+SC+FP++PI ETYQPRWD WGR+M+ L S+VP+MV+EGNHEIE Q    TF++Y +RFA PSEESGS S FYYSF+AGG+HFIMLGAY D++ +G QY WL+ DL  +DR+ TPWL A WHPPWY++Y +HY+E ECMR EME LLY YGVDIVF+GHVHAYER NRVY+Y LD CGPVY+TVGDGGN E++ V  AD+PG+CP     TP+     G  C  NF+SGPA G FCW+ QP++SAFRESSFGHGILEV N T+ALWTW+RNQD+  ++  GDQIYIVRQP+
Sbjct:   30 EARIPTTLDGPFEPLTVPFDPSLRGNAVDLPDDDQRVRRRVKGFEPEQISVSLSADYDSVWISWITGEYQIGDKIKPLDPKSVASVVRYGKLRYPPTHEATGYSLVYNQLYPFEGLQNYTSGIIHHVRLTGLKPNTLYFYRCGDPSIPAMSKIHHYRTMPVSGPRSYPERIAVVGDLGLTYNTTTTISHLTSNNPDLVLLIGDVTYANLY-LTNGTGSDCYSCSFPNSPIHETYQPRWDYWGRYMQSLVSKVPIMVVEGNHEIEEQAENKTFEAYSSRFAFPSEESGSSSTFYYSFNAGGIHFIMLGAYTDFSKSGKQYKWLEQDLANVDRSTTPWLAATWHPPWYSTYEAHYREAECMRLEMEELLYSYGVDIVFNGHVHAYERSNRVYDYNLDPCGPVYLTVGDGGNREKMAVQHADEPGRCPEP-STTPDQHLGDGAFCAENFTSGPAAGKFCWDXQPDYSAFRESSFGHGILEVKNETWALWTWYRNQDS--DNKIGDQIYIVRQPD 536          

Query:   13 QSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCP---SAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILE--------------------------------------VVNSTYALWTWHRNQDTYKEDSHGDQIYIV 1518
            ++ IPTTL+GPF+P T  FDPSLR  + DLP D  R+++ V    PEQI++++S+   S+WISW+TG+ QIG N+ PLDP  V S V+YG       +   G S+VY+QLYPFEGL NYTSGI+HHVR+ GLKP T Y+Y+CGD SIP MSE H F T+P+    +YP RIAVVGDLGLT NT+ TI HL  N+P ++L++GD+TYAN Y  T G G+ C+SC+FP++PI ETYQPRWD WGR+M+ L S+VP+MV+EGNHEIE Q    TF++Y +RFA PSEESGS S FYYSF+AGG+HFIM+GAY D++ +G QY WL+ DL  +DR++TPWLVA WHPPWY++Y +HY+E ECMR EME LLY YGVDIVFSGHVHAYER NRVY+Y LD CGPVY+TVGDGGN E++ V  AD+PG CP   +  D     G  C +NF+SGPA G FCW++QP++SAFRESSFGHGILE                                      V N T+ALWTW+RNQD+  +D  GDQIYI+
Sbjct:   30 EARIPTTLDGPFQPLTVPFDPSLRGNAVDLPDDDHRVRRRVKGFEPEQISVSLSADYDSVWISWITGEYQIGDNIMPLDPKSVQSVVQYGXLGYPPTNEASGYSLVYNQLYPFEGLQNYTSGIIHHVRLTGLKPNTVYFYQCGDPSIPXMSEIHHFRTMPVTGPRSYPERIAVVGDLGLTYNTTATIXHLTSNNPDLVLLIGDVTYANLY-LTNGTGSDCYSCSFPNSPIHETYQPRWDYWGRYMQSLVSKVPIMVVEGNHEIEEQAENKTFEAYSSRFAFPSEESGSSSTFYYSFNAGGIHFIMIGAYTDFSKSGKQYKWLEQDLANVDRSITPWLVATWHPPWYSTYEAHYREAECMRMEMEELLYSYGVDIVFSGHVHAYERSNRVYDYNLDPCGPVYLTVGDGGNREKMAVHHADEPGHCPEPLTTPDEHLGAGAFCAMNFTSGPAAGKFCWDRQPDYSAFRESSFGHGILELTYRPRLQSAENVYTRMTAQFNHLDYIXTVGFNVHNLQVKNETWALWTWYRNQDS--DDKIGDQIYII 570          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEF-GGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTLEGPF+P T   D S R  + DLP   PR+++ V    PEQI++++S+   S+WISW+TG+ QIG N+ PLDP+ V S V YG+     ++   G S++Y+QLYPFEGL NYTSGI+HHVR+ GL+P T Y Y+CGD SI  MS+   F+T+P     +YP +IAVVGDLGLT NT++T+DHL+ N P ++L+VGD+TYAN Y T G                             FM+PL S+VPMMV+EGNHEIE Q    TF SY +RFA PS ESGS S  +YSF+AGG+HFIMLGAY  Y+ +  QY WL+ DL ++DR VTPWLVAAWHPPWY++Y++HY+E ECM+                   VHAYER NRVYNY LD CGPVYITVGDGGN E++ +   D+PG CP       +F GG C  NF+ GPA G FCW+KQPE+SA+RESSFGHGILEV N TYA WTWHRNQD Y   +  D IYIVRQP+
Sbjct:  472 IPTTLEGPFKPVTVPLDDSFRGNAVDLPDTDPRVRRIVKGFEPEQISVSLSTTHDSVWISWITGEFQIGDNIKPLDPNNVSSIVTYGRYGFPMDNQSTGYSLIYNQLYPFEGLQNYTSGIIHHVRLTGLRPNTLYQYQCGDPSIADMSKVSYFKTMPASGPKSYPRKIAVVGDLGLTYNTTSTVDHLLANGPDLMLLVGDVTYANLYLTNGTG---------------------------FMQPLVSKVPMMVVEGNHEIEEQAGNRTFASYSSRFAFPSNESGSSSTLFYSFNAGGIHFIMLGAYTAYHKSDDQYKWLEKDLAKVDRNVTPWLVAAWHPPWYSTYTAHYREEECMK-------------------VHAYERSNRVYNYTLDPCGPVYITVGDGGNREKMAIAHXDEPGNCPEPSTTXDKFMGGFCAFNFTXGPAAGKFCWDKQPEYSAYRESSFGHGILEVKNETYAXWTWHRNQDMYSXSA--DLIYIVRQPD 928          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQ 1116
            IPTTLEGPF+P T   D S R  + +LP   PR+++ V    PEQI++++S+   S+WISW+TG+ QIG N+ PLDP+ V S V YG+     ++   G S++Y+QLYPFEGL NYTSGI+HHVR+ GL+P T Y Y+CGD +I  MS+   F+T+P+    +YP RIAVVGDLGLT NT++T+DHL+ N P ++L+VGD+TYAN Y  T G G+ C+SC F   PI ETYQPRWD WGRFM+PL S+VPMMV+EGNHEIE Q    TF SY +RFA PS ESGS S  +YSF+AGG+HFIMLGAY  Y+ +  QY WL+ DL ++DR VTPWLVAAWHPPWY++Y++HY++ ECM+ EME +LY+
Sbjct:   34 IPTTLEGPFKPVTVPLDDSFRGNAVELPDTDPRVRRIVKGFEPEQISVSLSTTYDSVWISWITGEFQIGDNIKPLDPNNVSSIVTYGRYGFPMDNQSTGYSLIYNQLYPFEGLQNYTSGIIHHVRLTGLRPNTLYQYQCGDPNIADMSKISYFKTMPVSGPKSYPRRIAVVGDLGLTYNTTSTVDHLLANGPDLMLLVGDVTYANTY-LTNGTGSDCYSCLFSQTPIDETYQPRWDYWGRFMQPLVSKVPMMVVEGNHEIEEQAGNRTFASYSSRFAFPSNESGSSSTLFYSFNAGGIHFIMLGAYTAYHKSDDQYKWLEKDLAKVDRNVTPWLVAAWHPPWYSTYTAHYRDEECMKVEMEDILYK 398          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTLEGPF+P T   D S R  + DLP   PR+++ V    PEQI++++S+   S+WISW+TG+ QIG N+ PLDP+ V S V YG+     ++   G S++Y+QLYPFEGL NYTSGI+HHVR+ GL+P T Y Y+CGD SI  MS+   F+T+P     +YP +IAVVGDLGLT NT++T+DHL+ N P ++L+VGD+TYAN Y T G                             FM+PL S+VPMMV+EGNHEIE Q    TF SY +RFA PS ESGS S  +YSF+AGG+HFIMLGAY  Y+ +  QY WL+ DL ++DR VTPWLVAAWHPPWY++Y++HY+E ECM+ EME +LY+YGVDIVF+GHVHAYER  RVY Y LD CGP            ++ +   D+  + P       +   +  +N S   +   FCW      + +R++        V N TYALWTWHRNQD Y   +  D IYIVRQP+
Sbjct:   34 IPTTLEGPFKPVTVPLDDSFRGNAVDLPDTDPRVRRIVKGFEPEQISVSLSTTHDSVWISWITGEFQIGDNIKPLDPNNVSSIVTYGRYGFPMDNQSTGYSLIYNQLYPFEGLQNYTSGIIHHVRLTGLRPNTLYQYQCGDPSIADMSKVSYFKTMPASGPKSYPRKIAVVGDLGLTYNTTSTVDHLLANGPDLMLLVGDVTYANLYLTNGTG---------------------------FMQPLVSKVPMMVVEGNHEIEEQAGNRTFASYSSRFAFPSNESGSSSTLFYSFNAGGIHFIMLGAYTAYHKSDDQYKWLEKDLAKVDRNVTPWLVAAWHPPWYSTYTAHYREEECMKVEMEDILYKYGVDIVFNGHVHAYERSXRVYXYTLDPCGP------------KMAIAHTDEL-ELPEPSTTPDKLWRLLRIN-SQKASSRKFCWTSSXN-TCYRDALAMDS--RVKNETYALWTWHRNQDMYSNSA--DLIYIVRQPD 491          

Query:  148 PEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 1479
            P+Q+ +++     M +SWVT            +   V S V YGKESG Y     G    Y           Y+SG +HHV I  L+P T Y+Y+CG S       E +F+T P       P   AV GDLG T  T++T+ H+   D  ++L  GDL+YA                        +T QP WD +GR +EP  S+ P MV EGNHE+E  P ++   FK+Y  R+ +P +ESGS SN YYSF+  G H IMLG+Y D++A   QY WL+ DL ++D  VTPW+V   H PWYN+ S+H  E E MR+ ME LLY   VD+VF+GHVHAYER  RVYN   D CGPVY+T+GDGGN E + + F                                    N     S +RE SFGHG L V+N T+A W WHRN ++
Sbjct:   49 PQQVHISLVGKDHMRVSWVT------------ESKHVKSIVEYGKESGMYNGKATGEHTSYKYFL-------YSSGKIHHVTIGPLEPATTYFYRCGGSG-----PEFSFKTPPQK----LPLEFAVAGDLGQTEWTNSTLQHIGSMDYDVLLXPGDLSYA------------------------DTQQPLWDSFGRIVEPYASKRPWMVTEGNHEVESIPIINPTGFKAYNARWPMPYQESGSTSNLYYSFEVAGTHVIMLGSYADFDAKSDQYKWLQADLAKIDXKVTPWIVVLLHAPWYNTNSAHKGEGESMRKAMEELLYNARVDVVFAGHVHAYERFTRVYNNEADPCGPVYMTIGDGGNREGLALKFE-----------------------------------NPASPLSLYREPSFGHGRLRVLNETHAFWGWHRNNES 407          

Query:  142 NFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYI 1515
            + P+Q+ ++++    M ++WVT D                S V YG  SG   SV  G S  Y+ +        Y+SG +HH  I  L+  T Y+Y+CG         E  F+T P    + +P   AV GDLG T  T +T+DH+ Q    + L+ GDL+YA+                          Q RWD +G  ++PL S  P MV +GNHE E  P +    F+SY +R+ +P EES S SN YYSF+  GVH IMLG+Y DY+    QY WLK DL ++DR  TPWL+  +H PWYNS  +H  E + M   ME LLY   VD VF+GHVHAYER  RV     D CG V+IT+GDGGN E                        G+ H   S             PEWS FRE+SFGHG L + NST+ALWTWHRN D   E    DQ++I
Sbjct:   42 SLPQQVHVSLAGDEHMRVTWVTDD------------KSAPSVVEYGTSSGTXSSVAXGESTSYTYML-------YSSGKIHHTVIGPLEHDTVYFYQCG-----GQGPEFXFKTPP----AQFPITFAVXGDLGQTGWTKSTLDHIDQCKYDVHLLPGDLSYADYI------------------------QSRWDTFGELVQPLASARPWMVTQGNHEKENIPLLKD-GFQSYNSRWKMPYEESXSSSNLYYSFEXAGVHAIMLGSYTDYDEYSDQYRWLKADLSKVDRQKTPWLLVLFHVPWYNSNKAHQGEGDSMMAAMEPLLYAASVDXVFAGHVHAYERTKRVNKGRSDTCGAVHITIGDGGNRE------------------------GLAHKYKS-----------PSPEWSVFREASFGHGELNIKNSTHALWTWHRNDD--DEPVRSDQVWI 411          

Query:  142 NFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYI 1515
            + P+Q+ ++ +      ++WVT D                S V YG  SGKY S+                   Y SG +HH     L+  T Y+Y+CG       + E  F+T P    + +P   AV GDLG T  T +T+DH+ Q    + L+ GDL+YA+                          Q RWD +G  ++PL S  P MV +GNHE E  P +    F+SY +R+ +P EESGS SN YYSF+  GVH IMLG+Y D +    QY WLK DL ++DR  TPW +  +H PWYNS  +H  E   M   ME LLY    DIVF+GHVH YER  RV N   DRCG V+IT+GDGGN E                        G+ H  + + P          PEWS FRE+SFGHG L +VNST+A WTWHRN D   E    DQ++I
Sbjct:  413 SLPQQVHISFAGDKHXRVTWVTDD------------KSAPSVVEYGTSSGKYSSML------------------YXSGKIHHTVXGPLEHDTVYFYQCG-----GQAPEFQFKTPP----AQFPITFAVAGDLGQTGWTKSTLDHIDQCKYDVHLLPGDLSYADYI------------------------QSRWDTFGELVQPLASARPWMVTQGNHEKENIPLLKD-GFQSYNSRWKMPYEESGSSSNLYYSFEVAGVHAIMLGSYTDXDEYSDQYRWLKADLSKVDRQKTPWXLVLFHVPWYNSNKAHQGEGXSMMAXMEPLLYAASADIVFAGHVHXYERTKRVNNGKSDRCGAVHITIGDGGNKE------------------------GLAH-KYKNXP----------PEWSVFREASFGHGELNIVNSTHAFWTWHRNDD--XEPVRSDQVWI 771          

Query:  520 IAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRN 1470
            + V GDLG T  T +T+ H+   D  ++L+ GDL+YAN                        + QP WD +GR +EP  S+ P MV EGNHEIE    G    +Y  R+ +P +ESGS SN YYSF+  G H IMLG+Y +++A   QY WL+ DL ++DR VTPW+V   H PWYN+ ++H  E E MRQ ME LLY+  VD+VF+GHVHAYER  RVYN   D CGPVY+TVGDGGN E + + F D                          PA            S +RE SFGHG L +VN T+A W WHRN
Sbjct:   17 VVVSGDLGQTEWTKSTLQHIGGMDYDVLLLPGDLSYAN------------------------SLQPLWDSFGRIVEPYASKRPWMVTEGNHEIENFPPGXM--AYNARWQMPYQESGSTSNLYYSFEVVGTHVIMLGSYAEFDAESDQYKWLQADLAKIDRKVTPWVVVLLHAPWYNTNTAHKGEGESMRQAMEELLYKARVDVVFAGHVHAYERFTRVYNNEADPCGPVYMTVGDGGNREGLALMFED--------------------------PAS---------PLSLYREPSFGHGRLRIVNETHAFWGWHRN 272          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF+P TRRFDPSLRRGS+DLPM+HPRLKKN T NFPEQI+LAISSPTSMW+SWVTG+AQIG +V PLDP+ V SEV YGKESGKY S  KG S VY+QLYPFEGL NYTSGI+HHVRIDGL+PGTKY+YKCGDSSIPAMSEEH FETLP+PS + YPHRIA++GDLGLTSN+STTIDH+I NDPSMILMVGDLTYANQY TTGGKGA C+SCAFPDAPIRETYQPRWDGWGRFMEPL S  PMMVIEGNHEIEPQVSGITFKSYLTR+AVPSEESGS SNFYYSFDAGG+HF+MLGAYVDYN+TGAQY+WLK DL+Q+DR  TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIE+VDVD AD+PG CPSAGDN PEFGGVCH+NFSSGPA+G FCW+KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQIY+VRQPE
Sbjct:    1 IPTTLDGPFKPVTRRFDPSLRRGSDDLPMNHPRLKKNATSNFPEQISLAISSPTSMWVSWVTGEAQIGSDVIPLDPASVASEVWYGKESGKYASRGKGNSTVYTQLYPFEGLSNYTSGIIHHVRIDGLEPGTKYFYKCGDSSIPAMSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIEPQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYVVRQPE 503          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQP 1527
            IPTTLEGPF+P T  FD  LRRGS+DLPMDHPRL++NVT  FPEQI+LAISSPTSMW+SW+TGD+QIG NVTPLDPS V SEV YGK S KY SVK G S VYSQLYPFEGLLNYTSGI+HHVR+D L+PGTKYYYKCGDSS PAMS E+ FETLP+P    YP RIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL+YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYN TGAQYAWLK DLHQ+DR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIEQV+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW++QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQIYIVRQP
Sbjct:   13 IPTTLEGPFQPVTHSFDSRLRRGSDDLPMDHPRLRRNVTSFFPEQISLAISSPTSMWVSWITGDSQIGSNVTPLDPSTVASEVWYGKRSRKYSSVKSGFSTVYSQLYPFEGLLNYTSGIIHHVRLDDLEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQP 514          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQP 1527
            IPTTLEGPF+P T  FD  LRRGS+DLPMDHPRL++NVT  FPEQI+LAISSPTSMW+SW+TGD+QIG NVTPLDPS V SEV YGK S KY SVK G S VYSQLYPFEGLLNYTSGI+HHVR+D L+PGTKYYYKCGDSS PAMS E+ FETLP+P    YP RIAVVGDLGLTSNT+TTIDHLI+NDPSMILMVGDL+YANQYRTTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQV+GITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYN TGAQYAWLK DLHQ+DR+VTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNY LD CGPVYITVGDGGNIEQV+VD ADDPGKCPSA DN PEFGG+CHLNFSSGPAKG FCW++QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK  S GDQIYIVRQP
Sbjct:   27 IPTTLEGPFQPVTHSFDSRLRRGSDDLPMDHPRLRRNVTSFFPEQISLAISSPTSMWVSWITGDSQIGSNVTPLDPSTVASEVWYGKRSRKYSSVKSGFSTVYSQLYPFEGLLNYTSGIIHHVRLDDLEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKRKSRGDQIYIVRQP 528          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            MAVA++ IPTTL+GPF+P TRRFDPSLRRGS+DLPM HPRL+KNVT NFPEQIALAISSPTSMW+SWVTGDAQIG NVTP+DP+ VGSEV YGK+SGKY SV KG SVVYSQLYPFEGL NYTSGI+HHV++ GL+PGT+YYYKCGDSSIPAMS+EH FET P PS + YP RIAV+GDLGLTSN+++TIDHL  NDPSMILMVGDLTYANQY TTGGKGASC+SCAFPDAPIRETYQPRWDGWGRFMEPLTS +PMMVIEGNHEIEPQ  GITFKSYLTRFAVP+EESGSKSNFYYSFDAGG+HFIMLGAYVDYN+TGAQ+AWLK DL  +DR+VTPWLVAAWH PWYNSY+SHYQEFECMR EME LL++Y VDIVF GHVHAYERMNRV+NY LD CGPVYITVGDGGNIE+VDVD ADDPGKCPSAGDN PEFGGVC  NFS+GPAKG+FCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YKE++ GDQIYIVRQPE
Sbjct:   23 MAVAETHIPTTLDGPFDPVTRRFDPSLRRGSDDLPMTHPRLRKNVTSNFPEQIALAISSPTSMWVSWVTGDAQIGLNVTPVDPASVGSEVWYGKKSGKYTSVGKGDSVVYSQLYPFEGLWNYTSGIIHHVKLKGLEPGTRYYYKCGDSSIPAMSQEHYFETFPKPSPNNYPARIAVIGDLGLTSNSTSTIDHLNYNDPSMILMVGDLTYANQYLTTGGKGASCYSCAFPDAPIRETYQPRWDGWGRFMEPLTSEIPMMVIEGNHEIEPQAGGITFKSYLTRFAVPAEESGSKSNFYYSFDAGGIHFIMLGAYVDYNSTGAQFAWLKKDLQSVDRSVTPWLVAAWHSPWYNSYASHYQEFECMRLEMEELLFRYRVDIVFDGHVHAYERMNRVFNYTLDPCGPVYITVGDGGNIEKVDVDHADDPGKCPSAGDNIPEFGGVCKSNFSTGPAKGNFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDNYKENAVGDQIYIVRQPE 532          

Query:    1 MAVAQSPIPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWG-----------------------------------RFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            M V++  IPTTL+GPF+P TRRFD SLRRGS+DLPM HPRLK NVTLNFPEQIALAISSPTSMWISW+TG +QIG NVTPLDP+ +GSEV YGK+SGKY +V KG S+VYSQLYPFEGLLNYTSGI+HHV+++GL+PGT+YYYKCGDSSIPAMS+E+ FET   PS   YP RIAV+GDLGLTSN+STT+DHL  NDPSMILM+GDLTYANQY TTGGKGASCFSCAFPDAPIRETYQPRWDGWG                                   RFM+PLTS+VPMMVIEGNHEIEPQ  GITFKSYLTRFAVP+EESGSKSNF+YSFD GG+HFIMLGAYVDYN TGAQ+ WLK DL  +DR+VTPWLVA  HPPWYNSY+SHYQEFECMR EMEALLYQY VDI+F+GHVHAYERMNRVYNY LD CGP+YITVGDGGNIE+VDVD AD+PGKCPS+GDN PEFGGVCH NF+ GPAKG+FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD+YKE++ GDQIYIVRQPE
Sbjct:   22 MVVSKRHIPTTLDGPFKPVTRRFDSSLRRGSDDLPMTHPRLKMNVTLNFPEQIALAISSPTSMWISWITGKSQIGLNVTPLDPASIGSEVWYGKKSGKYTNVGKGDSLVYSQLYPFEGLLNYTSGIIHHVKLEGLEPGTRYYYKCGDSSIPAMSQENYFETFAKPSPKNYPARIAVIGDLGLTSNSSTTVDHLSYNDPSMILMIGDLTYANQYLTTGGKGASCFSCAFPDAPIRETYQPRWDGWGSNCFPKLSTSVTSAYASRISSKDRWYDLLIRCLTIRFMQPLTSKVPMMVIEGNHEIEPQADGITFKSYLTRFAVPAEESGSKSNFFYSFDTGGIHFIMLGAYVDYNKTGAQFDWLKKDLQNVDRSVTPWLVATMHPPWYNSYASHYQEFECMRLEMEALLYQYRVDIIFNGHVHAYERMNRVYNYTLDPCGPIYITVGDGGNIEKVDVDHADEPGKCPSSGDNIPEFGGVCHSNFTFGPAKGNFCWKKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDSYKENAVGDQIYIVRQPE 566          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSPTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTLEGPF+P TRRFD SLRRGS+DLPMDHPRL KNVT +FPEQIALA+SS TSMW+SWVTG+AQIG NV PLDP  V SEV YGKESGKY S KKG S VYSQLYPFEGL+NYTSGI+HHV IDGL+PGTKYYYKCGDSSIPAMSEE+ F+TLP+PS  +YPHRIAV+GDLGL+SN+STTIDHL  NDPS+I+MVGDLTYANQY TTGGKG  CFSCAFPDAPIRETYQPRWDGWGRFMEPL SRVPMMVIEGNHEIEPQV+GITFKSYLTRFAVPSEESGS SNFYYSFDAGG+HFIMLGAYVDYN TG+QYAWLK+DL+Q+DRT TPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQY VDIVFSGHVHAYER+NRVYNY LD CGPVYITVGDGGNIEQVDV+ ADD                                   QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD YK+DSHGDQIYIVRQPE
Sbjct:   26 IPTTLEGPFQPVTRRFDSSLRRGSDDLPMDHPRLLKNVTGDFPEQIALALSSSTSMWVSWVTGNAQIGSNVVPLDPGSVASEVWYGKESGKYTSKKKGNSTVYSQLYPFEGLVNYTSGIIHHVIIDGLEPGTKYYYKCGDSSIPAMSEEYFFQTLPLPSPYSYPHRIAVIGDLGLSSNSSTTIDHLATNDPSLIIMVGDLTYANQYLTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLISRVPMMVIEGNHEIEPQVAGITFKSYLTRFAVPSEESGSNSNFYYSFDAGGIHFIMLGAYVDYNTTGSQYAWLKEDLNQVDRTKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERINRVYNYTLDPCGPVYITVGDGGNIEQVDVEHADD-----------------------------------QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDIYKDDSHGDQIYIVRQPE 493          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRY-----------GKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSI---PAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPFEPATR FD +LR+GS+D+P+  PRL        PEQIALA SS  TS+W+SWVTG+AQ+G ++TPLDPS V SEV Y           G  SG Y  V +G + VYSQLYP+ GLLNYTSG +HHVR+ GL+P T+YYY+CGDSS+     +S E +FETLP  + + YP R+AVVGDLGLT N+++T++HL +NDPS++++VGD+TYANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNHEIEPQ  G  +TF SYL RFAVPSEESGS + FYYSF+AGG+HFIMLGAYVDYN TGAQY+WL+ DL ++DR VTPW+VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NY LD CGPVYIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQIYIVRQP+
Sbjct:   36 IPTTLDGPFEPATRAFDRALRQGSDDVPLTDPRLAPRARPPAPEQIALAASSDATSVWVSWVTGEAQVGSHLTPLDPSTVRSEVWYSERPSPTAAAAGDVSGHYPHVARGKAEVYSQLYPYPGLLNYTSGAIHHVRLRGLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHEIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWVVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPD 555          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISS-PTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYG-------------KESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPA-MSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF PATR FD SLRRGS D+P+   RL        PEQI+LA S+ PTS+W+SWVTG AQ+G ++TPLDP+ + SEV YG             KE   Y  V +G + VYSQLYP+ GLLNYTSG++HHVR+ GL P T+YYY+CGDSS+ A +SEE +F TLP P+   YP R+AVVGDLGLT N+++T+DHL +NDPS++LMVGD+TYANQYRTTGG+G  CFSC+FPDAPIRE+YQPRWDGW RFMEPL SR+PMMVIEGNHEIEPQ  G  +TF SY  RFAVP+EESGS S FYYSFDAGG+HFIMLGAYVDYN TGAQY+WLK DL ++DR VTPW+VA+WH PWYNSYSSHYQEFECMRQEME LLYQ+ VDIVFSGHVHAYERMNRV+NY LD CGPVYI +GDGGNIE++D+D ADDPGKCPS GDN PEFGG+CHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY EDS GDQIYIVRQP+
Sbjct:    5 IPTTLDGPFTPATRAFDRSLRRGSEDVPLSDARLAPRARPPSPEQISLAASANPTSLWVSWVTGRAQVGSHLTPLDPTSIRSEVLYGARPSSSSAAGAGEKEEDGYPHVARGSAEVYSQLYPYPGLLNYTSGVIHHVRLSGLAPSTRYYYRCGDSSLKAGLSEERSFTTLPAPAPGAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSLVLMVGDMTYANQYRTTGGRGVPCFSCSFPDAPIRESYQPRWDGWARFMEPLASRIPMMVIEGNHEIEPQGHGGAVTFASYSARFAVPAEESGSNSKFYYSFDAGGIHFIMLGAYVDYNRTGAQYSWLKKDLQRVDRAVTPWVVASWHSPWYNSYSSHYQEFECMRQEMEGLLYQHRVDIVFSGHVHAYERMNRVFNYTLDPCGPVYIIIGDGGNIEKIDIDHADDPGKCPSPGDNHPEFGGLCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEDSVGDQIYIVRQPD 524          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISSP-TSMWISWVTGDAQIGKNVTPLDPSKVGSEVRY-----------GKESGKYESVKKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSI---PAMSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPT L+GPFEPATR FD +LR+GS+++P+  PRL        PEQIALA SS  TS+W+SWVTG+AQ+G ++TPLDPS V SEV Y           G  SG Y  V +G + VYSQLYP+ GLLNYTSG +HHVR+ GL+P T+YYY+CGDSS+     +S E +FETLP  + + YP R+AVVGDLGLT N+++T++HL +NDPS++++VGD+TYANQYRTTGG+G  CFSC+FPDAP+RE+YQPRWDGWGRFMEPLTSR+PMMVIEGNH+IEPQ  G  +TF SYL RFAVPSEESGS + FYYSF+AGG+HFIMLGAYVDYN TGAQY+WL+ DL ++DR VTPW VAAWHPPWYNSYSSHYQEFECMRQ ME LLYQ+GVDIVFSGHVHAYERMNRV+NY LD CGPVYIT+GDGGNIE++D+D ADDPGKCP  GDN PEFGGVCHLNF+SGPAKG FCW KQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD Y EDS GDQIYIVRQP+
Sbjct:   36 IPTKLDGPFEPATRAFDRALRQGSDEVPITEPRLAPCARTPAPEQIALAASSDATSVWVSWVTGEAQVGSHLTPLDPSTVRSEVWYSERPSPTAAAAGDVSGHYPHVARGKAEVYSQLYPYPGLLNYTSGAIHHVRLRGLRPATRYYYRCGDSSVRGGAGLSGELSFETLPSSAAAAYPRRVAVVGDLGLTGNSTSTVEHLARNDPSLVVVVGDMTYANQYRTTGGRGVPCFSCSFPDAPLRESYQPRWDGWGRFMEPLTSRIPMMVIEGNHDIEPQGQGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLRKIDRRVTPWAVAAWHPPWYNSYSSHYQEFECMRQAMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDPCGPVYITIGDGGNIEKIDIDHADDPGKCPGPGDNHPEFGGVCHLNFTSGPAKGKFCWEKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDAYGEDSVGDQIYIVRQPD 555          

Query:   22 IPTTLEGPFEPATRRFDPSLRRGSNDLPMDHPRLKKNVTLNFPEQIALAISS-PTSMWISWVTGDAQIGKNVTPLDPSKVGSEVRYGKESGKYESV-----KKGVSVVYSQLYPFEGLLNYTSGIVHHVRIDGLKPGTKYYYKCGDSSIPA-MSEEHAFETLPMPSQSTYPHRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLTYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIEPQVSG--ITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNATGAQYAWLKDDLHQLDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYMLDRCGPVYITVGDGGNIEQVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGSFCWNKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYKEDSHGDQIYIVRQPE 1530
            IPTTL+GPF PATR FD SLRRGS D+P+  PRL        PEQIALA S+ P S+W+SWVTG AQIG ++TPLDP+ + SEV YG+     ++V      +G + VYSQLYP+ GLLNYTSG++HHVR+ GL+P T+YYY+CGDSS+   +S+E +F TLP P+   YP R+AVVGDLGLT N+++T+DHL +NDPSMILMVGD+TYANQY TTGG+G  CFSC+FPDAPIRE+YQPRWDGWGRFMEPLTS+VPMMV EGNHEIEPQ  G  +TF SYL RFAVPSEESGS + FYYSF+AGG+HFIMLGAYVDYN TGAQY+WL+ DL ++DR VTPW+VA+WH PWYNS SSHYQEFECMRQEME LLYQ+GVDIVFSGHVHAYERMNRV+NY LD CGPVYIT+GDGGNIE++D D ADDPG CPS GDN PEFGGVCHLNF+SGPAKG FCW +QPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTY E S GD+IYIVR+P+
Sbjct:   42 IPTTLDGPFTPATRAFDRSLRRGSEDVPLSDPRLAPRARPPSPEQIALAASADPISLWVSWVTGRAQIGSHLTPLDPTAIRSEVWYGERPASADTVGHPHVARGSAEVYSQLYPYPGLLNYTSGVIHHVRLVGLRPSTRYYYRCGDSSLKGGLSDERSFRTLPAPAPDAYPRRVAVVGDLGLTGNSTSTVDHLARNDPSMILMVGDMTYANQYLTTGGRGVPCFSCSFPDAPIRESYQPRWDGWGRFMEPLTSKVPMMVTEGNHEIEPQGHGGAVTFASYLARFAVPSEESGSNTKFYYSFNAGGIHFIMLGAYVDYNRTGAQYSWLEKDLQKVDRRVTPWVVASWHSPWYNSCSSHYQEFECMRQEMEGLLYQHGVDIVFSGHVHAYERMNRVFNYTLDSCGPVYITIGDGGNIEKIDTDHADDPGSCPSPGDNQPEFGGVCHLNFTSGPAKGKFCWERQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDTYGEHSVGDEIYIVREPD 553