ppa003983m, ppa003983m (mRNA) Prunus persica

Query:    7 DMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +++RTE +KS S   D+  +P++S WL +NLEEMDQS+K+MLKLI+EDGDS  K  E Y Q +PELI   E+FYR+YRSLA  YDH+T E  K + S +  QG G S+ G +  S   +PD +    KS  +                   K                  +S V+NYL          +  ++KI + E E+  +K +LQ +   LN + + + E+      +E+    +K  + E+  L  EL  R+++E  Q          DIAM +++L  E++ V +LQE++ RY   +  R+ E+ ELK  + DA   F LEK+ L A IS L + Q+ L+ +++E  LR ++LE+EI++ +T                           AE    +  +NK  D   LK+D +M+E+DEL+A+V                                                  E QK + S+       AE+KREAIRQLCFSLEHYR+ Y  LRQAF  H+R AV
Sbjct:  174 NLKRTESKKSHSWWWDSHISPKNSKWLADNLEEMDQSVKRMLKLIEEDGDSFAKKAEMYYQKRPELISHVEDFYRIYRSLAERYDHVTGELRKNILSDLQSQGSGISDLGSEPASTCPSPDQRERRRKSGRRAAGFDFFLGSGGSSSDLYNKGDESSSLSDSESGSD---DSSVNNYL--------GLRAAKEKIQLSEEEIVRLKTELQ-KYGPLNFTNNFQAEL------VELPPRDIKMQESEL-DLVEEL--RITKERLQ----------DIAMWKAKLDREKREVSKLQERVGRYKTSLSDREHEIRELKEVISDADHNFELEKSLLMAKISKLLDDQSHLEEKLKEWELRCQSLEEEIKQADT---------------------------AESGDRINDLNKSLDALNLKHDTLMSERDELSARV--------------------------------------------------ERQKGLVSE------AAEEKREAIRQLCFSLEHYRNDYNRLRQAFTVHKRPAV 593          

Query:  979 EKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            + A+L+  +S    K  +L+  +EE   R    E+E  + + + +  E   V  ++  Q EI  LK E++ER   V+A+NK+ D  K+ YD++MAEKDEL+A+V T+ A+++S DNQIQ++E HLR+L  E  ++IAG ESA +LVDEL  RV+EL++EV+ QRV ISD AE+KREAIRQLCFSLEHYRSGY+ELRQAF+GH+R  + A+
Sbjct:   19 QTAELENRVSESDHKICMLEEELEETKKRLMGSEEENEKLKHE-LTNEISVVKHQLEDQREIEQLKAELSERGDIVQALNKNLDALKVTYDMLMAEKDELSARVDTLIADVNSWDNQIQQLEDHLRQLRIERVELIAGTESARKLVDELSWRVKELEREVERQRVVISDRAEEKREAIRQLCFSLEHYRSGYQELRQAFIGHKRLPILAS 227          

Query:  589 LETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQ----------------LQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCE---TDKMEMERMHVAQ 1140
            LE E   V E  +    + N     +++I  L  +LE TK+RL GS++E  KLKHELT+ +S   HQ++ Q                +Q + +++  L+           EL  ++    AD+   D ++ +L+    D   Q  +E+ +L A   S  +        ++E S R K LE E+ R     +D+ E +R  + Q
Sbjct:    6 LELEKRQVLELQKQTAELENRVSESDHKICMLEEELEETKKRLMGSEEENEKLKHELTNEISVVKHQLEDQREIEQLKAELSERGDIVQALNKNLDALKVTYDMLMAEKDELSARVDTLIADVNSWDNQIQQLE----DHLRQLRIERVELIAGTESARK-------LVDELSWRVKELEREVERQRVVISDRAEEKREAIRQ 197          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLT---KEAHKIMPSVIPVQG---FGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNG--TXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELT-------------HRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQE--------QFSLEK--ADLQADISSLTEKQTILD---TRIEEGSLR--------------NKNLEDEIRRCETD---KMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFS 1530
            M  +   +  +  S   D+  +P++S WL ENL +MD  +KQM+KLI+ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   ++A + M    P Q      DS +G    +   TP+   ++                         +NG  T              LN    +   P++     ++G  +K            EK    R + N  K     ++R   D +   ER   +++E+  LK  LT              +  E    ++  +   QED   L  +          L++ + R  ++  G  L+  +    + D +         QF LE     L A    LTEKQ  L    T I+E  LR              +   ++E+R   T+   K ++ +        LQDE+  +K E           N+  + F L    ++ +   L   +  ++A L     +++ +E   + L  E   +I   E+   +V +L L     Q  +++ ++A       +   IR   FS
Sbjct:    1 MASLSHPDSRRKYSWWWDSHISPKNSKWLQENLTDMDAKVKQMIKLIEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATGALRQAQRTMAEAFPNQVPFLTDDSPAGSSAEAEPHTPEMPPAVRAFFEPDELQKDALGLSSSHFHAVKRNGAFTEEPDSVSSKKGLKQLNDLFGSGDAPNIAKF--AEGRARK----GLNFHDADEK---ERNVQNTDK-----VSRAQEDSKGLNERAGKAENEVQTLKEALTKLEAERETSLLQYQQCLERISDLERTISHSQEDAGKLNERASKSEVEAAALKQDLARVESEKEGALLQYKQCLEKISDLESKLRTNHSLQFELESLAQKLGAQCEELTEKQKELGRLWTSIQEERLRFMEAETTFQSLQHLHSQSQEELRSLATELQSKGQILKDMETHNQGLQDEVHKVKEE-----------NRGLNEFNLSSAKLLEKNALLENSLSDLSAELEGLREKVKALEESYQSLLGEKSILIHVNENQQSIVQKLVLVTVLEQLGLEATQLATERNTLDEECRIRSEQFS 539          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLT---KEAHKIMPSVIPVQ 303
            M  +  ++  +  S   D+  +P++S WL ENL +MD  +K M+KLI+ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   ++AH+ M    P Q
Sbjct:    1 MATLSHSDSRRRYSWWWDSHISPKNSKWLQENLTDMDVKVKAMIKLIEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATGELRQAHRTMAEAFPNQ 107          

Query:   70 ESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKE---AHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRL--SEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-----LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQR 1470
            + S WL ++L++M++ ++ MLKLI+EDGDS  K  E Y + +PELI   EE Y+ YR+LA  YD ++ E   A+  + S+ P Q     +   +  +P    + +     +A QV                  K                 L  P +   +  L         Q+ I  L+TE   VK   +     + L+K+   EI + + +++    RL+   +  + ++ E    L  +      Q  L  +Q+       ++   R+ + E +EK+     D F  + E                 +  D          K T  +  +E       +L++E++  E  +M +       EMA     L +++  L+  V+ +   V+ +  +    + K + +  +KD L   V  +  NL   + ++  ++   + + + + ++   +  AHR +D+L    E LQK++ + R
Sbjct:   21 KQSKWLEQHLQDMEEKVQNMLKLIQEDGDSFAKRAEMYYKRRPELINFVEETYKSYRALAERYDKISTELQNANNTLASIFPEQVQFAMDEDDEDCTPQCRKECRELSQSNAPQVPKAPGKKDVKGLLTLATKKLQQKKIKAAAPAVPKSGLTKPEALKEIDRL---------QKGILALQTEKEFVKSSYE-----IGLAKYW--EIEKQITEMQEKNSRLQDEFNASLAIEDEDARNLMATTALRSCQMTLDNLQKTQEETVEEVKMGRQRITEAREKL-----DSFKNNQE-----------------KPCD--------NHKSTGAEETLE-------SLDEEMK--EQFEMGLNPSLTMTEMAEKIDELVNKVISLQTVVSSQTALVKRLRTETGELQTKIESMEDDKDTLTGSVKNLGHNLRELEKKLHGIQDPNQNVESRNNNLQTHFTEAHRNLDQL---FETLQKKLHNMR 442          

Query:   70 ESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKE---AHKIMPSVIPVQ---GFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGW--QQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQF-SLE--KADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCET 1104
            + S WL +NL ++++ ++ MLK+I +DGDS  +  E Y + +PELI   EE++R YR++A  YDHL++E   A++ + +V P +      D E   D   P      +  L K+   ++                 K                 L        V S      ++ W  + +IT +++ +S ++++       +   + R  E AR   D E    +   +  E ++        LS E   +     V   D+A          + + EL EK++   A +  +   V  L+   ++ Q Q  +LE  K  L  D   ++ K   L+  +      N+++ED+ +  +T
Sbjct:   21 KQSKWLEQNLHDVEEKVQFMLKIIDDDGDSFAQRAEMYYRKRPELINLVEEYFRAYRAIAERYDHLSRELQHANRTIATVYPEKVQFAMDDEEENKDFLVPTPAISKRKQLKKTISSIIAATCSGLSKTEALDEIDK------------IQKEILMLQTEKEFVKSSYERGAARYWEIESQITEMQSRVSDLQDEFG-----IGTKQERVAEEARHSQDHETLSHQFLPNQMEELE--------LSTEQESLTTSTTVTAPDVA----------ERIDELVEKVITLEAAVSSQTALVRRLRLETNELQTQVRTLEENKETLIEDSDKMSTKLIELEEELSRVQSLNRSVEDQNKHLQT 344          

Query:   52 DNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKE-AHKIMPSV--IPVQGFGDSES 324
            D+ N+P  S WL   L E+D+  K MLK+I+ED DS  +  E Y + +PELI   E+FYR +RSLA  YD +  +   ++ P++  +P++   DS S
Sbjct:   14 DSHNSPRRSPWLQSTLAELDEKTKAMLKIIEEDADSFGRRAEMYYKKRPELINMVEDFYRAHRSLAERYDQVRSDPGARLGPTLKKLPMRKLYDSGS 110          

Query:  592 ETELSSVKEKLQMRRLILNLSKHRENEIARLV----ADLEVTKERL-------KGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQL----HWERKHVLELQEKIVRYSADIFGRDLEVM------ELKSALHDA----------QEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEM----ERMHV-------------AQEMALQDEISGLKVEVAERNGHVE---AVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEE-LQKEVDSQRV-AISDGAEQKREAIRQLCFSLE 1536
            E +L   +E+L   R I+N  + + NEI R +     +LE  ++++       K  +D+I     ELT +  ++A  M+G L+V ++++ +L+ +L      E + +L+    I+      F  ++E        EL+S +H+           +E+    +  L+  +  + EK+  L+ +++    + K+L+ E +R E +K +M    E +H+              QE+ + +E   LKV   ER+ H      + ++ D+ + + +++  E+++L  +      +  + D +   +   +R +  E E +   + S    + + KL +EE +Q+E+++ R+   S  A  K E +R+    +E
Sbjct:  276 ERKLQEGEERLCEGRRIINQREEKANEIDRTLKLKERNLEEAQKKIDLDSLNVKVKEDDINNRLAELTVK-EKQAESMRGILEVKEKELIVLQEKLSARERVEIQKLLDEHRAILDTKKQEFELEMEQKRNSVDEELRSKVHEVEQKEVEVLHREEKLGKREQALEKRLERVKEKEKELEAKLKTLKEKEKSLKAEEKRVEGEKKQMLADKESLHLLKDELEKIRADITEQELQIHEETERLKVTEEERSEHHRLQLELKQEIDKCRHQEEMLQKEREDLKQERIMFEKDWEALDEKRAVITKEMREIGDEKEKLEKLHLSEEERLKKEKLAMEEHIQRELEAVRIEKESFAAIMKHEQLRKRDLEIE 642          

Query:  592 ETELSSVKEKLQMRRLILNLSKHRENEIAR-LVADLEVTKERLKGSDDEIVKLKHELTHRLS--EEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADL-------QADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVE------------VAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQ 1518
            E E+   +EKL  R   L     R  E  + L A L+  KE+ K    E  +++ E    L+  E  H ++ +L+ ++ DI   E Q+H E + +   +E+     ++     LE+ +        +E    E+ DL       + D  +L EK+ ++   + E     + LE ++   E ++++ E++  A E  +Q E+  +++E            + +R+  +E  N+  +  K   +   A ++E   +++ +         +I+EM+   RR+  E ++++           +L+    E++K++D   +      +Q+ + I++
Sbjct:  422 EVEVLHREEKLGKREQALEKRLERVKEKEKELEAKLKTLKEKEKSLKAEEKRVEGEKKQMLADKESLHLLKDELEKIRADITEQELQIHEETERLKVTEEE----RSEHHRLQLELKQEIDKCRHQEEMLQKEREDLKQERIMFEKDWEALDEKRAVITKEMREIGDEKEKLE-KLHLSEEERLKKEKL--AMEEHIQRELEAVRIEKESFAAIMKHEQLRKRDLEIEMQNRQDEIQKRLQERERAFEEERERELNNINHLKEVARREIEEMKTERRRIEKEKQEVLLNKR-------QLEGHQLEMRKDIDELGILSRKLKDQREQFIKE 738          

Query:  571 QQKITVLETELSSVKEKLQMRRL------------ILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHE------LTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHL-------RRLNAEHEDMIAGYESAHRL-------VDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLE 1536
            Q++    +T + S+K KL+ R              +LN  K R  ++ +   DL+    +++ ++D I  L  E      L   L  +   +Q  L   +ED   LE  L  + + +  LQ++I   S +I  ++  V  L S+L           A  + + ++L    +    ++ E  L  K L+DE+   + ++++ +   V     L  +++ L VE  + N  + A+ K+F+  +L  +    +K   +AK+      L  ++N++ ++E  L       R+ NA   D+    E   +L       V  LK  ++  Q+ + +     SD  E++ + +R LC  LE
Sbjct:  138 QKEKAASQTTIESIKTKLKEREAAIVSLEKEFGLKLLNEEKERAKQLGKAKEDLQSLMNQVQSANDIITGLGQELQSERRLIQELKAQIDNLQTDLTKAREDKKALEEDLKLKLESIEVLQDRINLLSLEIKDKEDNVENLNSSL-----------AQKELEFNNLISDHSQTKNQLVESDLEIKGLKDELLGTQ-EELKSKNSLVDD---LNAQVNSLIVEKDDSNRQLAALQKEFNDLRLSSE----KKAAFDAKL------LGEKENELHQLEEKLKNALNEARKSNATIADLTQEKEDLSKLLAIELSNVKNLKHELQITQETLKASTNEASD-LEKQLKQLRDLCLKLE 465          

Query:  529 LVPSLKVHFDS-QGWQQKITVLETELSSVKEKLQMRRLILNLS-KHRENEIARLVADLEVTKERLKGSDDEIVKLKHELT---------HRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGR---DLEVME--LKSALHDAQEQ------FSLEKADLQ-------ADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETD--KMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISD 1485
            L   LK+  +S +  Q +I +L  E+   ++ ++     LN S   +E E   L++D   TK +L  SD EI  LK EL          + L ++ +     L V ++D     + L  E   +    EK   + A + G    +L  +E  LK+AL++A++        + EK DL        +++ +L  +  I    ++  +    +LE ++++      K+E E   V  E A   E+    ++ A+++G V A     +  K+K +++   KDEL  + H + +   +RD+  +E+    ++  +  +D+    ++   L  EL+   ++  K+ + Q+   +D
Sbjct:  243 LEEDLKLKLESIEVLQDRINLLSLEIKDKEDNVEN----LNSSLAQKELEFNNLISDHSQTKNQLVESDLEIKGLKDELLGTQEELKSKNSLVDDLNAQVNSLIVEKDDSNRQLAALQKEFNDLRLSSEKKAAFDAKLLGEKENELHQLEEKLKNALNEARKSNATIADLTQEKEDLSKLLAIELSNVKNLKHELQITQETLKASTNEASDLEKQLKQLRDLCLKLEAEVCTVLAESAKAKEMLQRSLDEAKQSGEVLAS----ELMKVK-ELLKKTKDELQHRSHELASVSENRDSLQKELVDVYKKAESVAQDLKEEKKAVITLNKELQALEKQTLKDKEVQKSLKTD 583          

Query:  574 QKITVLETELSSVKEKLQMRRLILNLSKHR-ENEIARLVADLEVTKER---LKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKA-DLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIR 1515
            Q++  LE EL + K  ++     LN  K   E ++A L    E   +R   L   + EI+ L+ ++  + S+E  ++     +   +IA+   +  +E +  LE + K+V    +   R  E+ E+  +    +E F+LE+  +L+    +L EK+  +  ++   SL  K  E  +   E D +E+E++H+ +E   ++EI+ +K+ + +    +E   K  D  K K + + +E  EL      +   +     Q  E+      L A+  +  A +ES     +EL+   E + +E    R+AIS   + +R++++
Sbjct:  264 QELNRLEKELEASKSNIEKELRALNEEKSNLELKLASLTTREEDVVKREALLNKKEHEILILQEKIASKESDEVQKL-----MALHEIALKTRKAEFEAE--LETKRKLVEDEIEAKRRASELREVDLS---NREDFALEREHELEVQSRALAEKEKDVTEKLN--SLDEK--EKYLNAAEKD-VELEKIHLEKE---KEEINKMKLNIEKSLSSLEDKKKQVDHAKEKVEAMKSETSELLVLEMKLKEEIDVIRAQKLELMAEADELRAQKANFEAEWESIDEKREELRNEAERIAEE----RLAISKFLKDERDSLK 560          

Query:  571 QQKITVLETELSSVKEKLQMRRLILNLSKH----RENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMAL---QDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRV------AISDGAEQKREAIR 1515
            +Q ++  +  +   +E+L   + +LN  +     R  E+ RL  +LE +K  ++     + + K  L  +L+         L   +ED+   E+ L+ +   +L LQEKI    +D      EV +L  ALH+        KA+ +A++ +   K+ +++  IE     ++  E ++   E   +E E     Q  AL   + +++     + E+  ++ A  KD +  K+  +    E +++   +    ++L  +  Q+   +  +  + +E  +++         +D ++ +  EL  E D  R       A  +  ++KRE +R
Sbjct:  228 RQSLSERQKNVQQGQERLIDGQALLNQREEYIFSRSQELNRLEKELEASKSNIEKELRALNEEKSNLELKLAS--------LTTREEDVVKREALLNKKEHEILILQEKIASKESD------EVQKL-MALHEI--ALKTRKAEFEAELET---KRKLVEDEIEAKRRASELREVDLSNREDFALEREHELEVQSRALAEKEKDVTEKLNSLDEKEKYLNAAEKDVELEKIHLEKEKEEINKMKLNIEKSLSSLEDKKKQVDHAKEKVEAMKSETSELLVLEMKLKEEIDVIRAQKLELMAEADELRAQKANFEAEWESIDEKREELR 535          

Query:  106 MDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQM-----RRLILNLSKHRENE--IARLVA---DLEVTKERLKGSDDEIVKLK-----------------------------------------HELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M++S+KQMLKLI+EDG SL K  E   Q +P+LI   +EF  M +SLA CY+++T E    +PS   VQG  +SESG  H  PL+TPD KL  HK++++                   K G+               NS  + Y   SL V+ D     +KI V+ T+LSS++EKL+M     R  +LN  ++R  E  ++R++    +L +TK +L+ S+D++ +LK                                          EL  +++E + ++QGQL+V +E+I ML ++L+ E + VL+LQE+I  Y +D+   D E+     AL DAQE  S+EKA LQ++I  L+EKQ +L+ ++ E  L+ K +ED++R+CE +KM+M+ +H AQE+ALQ EIS LKVE+ +R  HVE +NK FD  K KYD++MAEKD ++AKV+T+ A+++SRDNQI++MEGHL++L+ EHE +IAG +S+ +LVDEL+L+V EL+KEVD QRV +S  AE+KR AIRQLCFSLEHYRSGYKELR+AFLGH+R +V A+
Sbjct:    1 MERSVKQMLKLIEEDGVSLAKKAEMCRQTRPDLISKIKEFNSMQQSLAECYEYVTTELTNSIPSEFDVQGVDNSESGHGHDPPLLTPDQKLGFHKASNRA----PSVSSHGASSDLSLKEGSESFSFSSSDSESESFNSSGNAYY--SLPVNTDRSELHKKIIVMGTDLSSMEEKLRMHEEENRDSMLNGEENRNYEELLSRIIGYEEELRLTKVKLQLSEDDVTRLKIELEKSVFFRDLSGTLQAQLELALKDIQMREDDLQVERKRVLELQKKVAEGSEELQGQLKVAEEEITMLNAKLNTESRRVLDLQERITCYKSDLSDHDHEI----KALKDAQENLSVEKAHLQSEILDLSEKQNMLEVKLREWDLQGKFMEDKLRQCEAEKMQMKNLHDAQEIALQGEISQLKVELIDRGEHVEVLNKKFDSLKSKYDMLMAEKDGMSAKVNTLIADVNSRDNQIRQMEGHLQQLHTEHEKLIAGSQSSRKLVDELRLKVVELEKEVDGQRVELSAVAEEKRAAIRQLCFSLEHYRSGYKELREAFLGHKRHSVMAS 545          

Query:  106 MDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMR----------------------------------RLILNLSKHRENEIARLVADLEV-------------------TKERLKGSDDEIVKLK-HELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            MDQ+  ++LK+I++DG SL K  E     +P+LI   EEF  +YRSLA  YDHL  E +K  PS   +Q  G +       +P++TPD KL LH++ HQV                  K+G+               NS    Y   SL V+ D +G  QKI  L   L  +  KLQ+                                   +L L LS   E E+ARL  +LE                    T  R++ +D E+ +++  EL   L++  +++QG L++ QE+I ML ++L  E    L+LQE+IV+Y  D+   D EV   K AL +A+E F  EKA LQ++ISSL E++T+L+ R+ +  L+ ++LE+++++CET+K +++ ++  Q + LQ EIS LKVE+ ++ GH+E VNK+ D  K KYD+VMAEKD +NAK++T+ A+LSSRDN+I +ME  LRR+  E+ ++IAG ES  R V+EL+LRV EL+KEVD QR  +S GAE+KREAIRQLCFSLEHYRSGYKEL QAF  H+R AV A+
Sbjct:    1 MDQTASRVLKMIEQDGASLAKKAEMCKMTRPDLIAEIEEFCSLYRSLAERYDHLNAELYKSTPSEFQMQDAGSAPD-----TPMLTPDQKLGLHQTGHQV----ESASSGGASSDLSPKDGSDSSSSSDSESDS--FNSSGDAYY--SLPVNSDRKGLHQKIIELRNGLPIMDIKLQLNAEDNGDCMLDAQEKENYEELLGRSIMYEEELRDSKLKLQLS---EEEVARLKGELEKRESDMVLAETLQGQLELAHTDLRMREADLEVERIRVMELQQGLADRTNELQGHLKLAQEEINMLRTKLDSEFWQALDLQERIVQYKNDVSALDDEVKASKLALLNAEENFLAEKAHLQSNISSLLERETMLEARLRDWELKGESLEEKLKQCETEKKDLQLVYDIQRIGLQGEISELKVELGDKGGHLEIVNKNLDSLKFKYDMVMAEKDGMNAKINTLIADLSSRDNEIGQMEERLRRIRIENAELIAGSESLQRTVNELRLRVVELEKEVDKQRGELSAGAEEKREAIRQLCFSLEHYRSGYKELCQAF--HKRHAVMAS 540          

Query:    7 DMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGS--PLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRR------------------------------LILNLS-KHRENEIARLVADL----------EVTKERLKGSDDEI----VKLKHELT-----------------------HRLSEEAHQMQGQLQVVQEDIAMLESQLH------------------------WE------RKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +M+R +  KS S   D+  +P++S WL ENLEEMD+S+++MLKLI+EDGDS  K  E Y Q +PE   L+EEFYRMYRSLA  YDH+T E  K +PS +  Q  G S+ G +  S  P   P+ +LS  K  ++                   +                  +S V+NY V  L  +       +K+  LE EL  +K++LQM++                               I N S +H E E+ARL  +L           + KE +   D+ +     +L+ E+T                         L++E    + +LQ  +++IA L+ QL                         W+      ++ V +LQE+I R    +  RD E+ +LK A+ DA+++   EKA ++A+IS L E++T LD ++ E   R + LED+IR+ +T+K E E  H +       EI+ LK E  ER+ H+E +NK  +  KL       E+D LNA+V  + A++ SRD+QI +M+ HL++L+ EH ++IAG E A +LV  L+ +  +L+KEV+ Q++AI++GAE+KREAIRQLCFSLEHYR+GY  LR+AF+ H+R  V
Sbjct:   11 NMKRLQSRKSHSWWWDSHVSPKNSKWLAENLEEMDRSVRRMLKLIEEDGDSFAKKAEMYYQKRPELVSLVEEFYRMYRSLAERYDHVTGELRKNIPSDLQSQSSGISDIGSELTSTWPSPVPEQRLSHRKPGNRAAGFDFFLGSGGSSSDLQKEGDESSTLTDSEPESD---DSSVNNYSV--LLGNGGDNALSRKVIELEIELREMKDRLQMQQEDNGDGSYRGARNENFEYLLARIAGYEQELKIANQSIQHSEEEVARLNIELHRYKSLEAVNSLQKEFISSKDENVKTEDSELESEITQASKLKENTDGLEAGTVDSDSKIRALTDELRITKEKLQYAEKEIASLKLQLESNRPSEKVDNLQDQLILAHKDINTWKTRLNAEKREVSKLQERIARLRTSLSDRDHEIRDLKLAVSDAEQKIFPEKAQIKAEISKLLEERTSLDEQLREWESRCRCLEDDIRKLQTEKSETEERHYS-------EINQLKAETVERDCHIENLNKSLNALKL-------ERDALNAQVVLLKADIISRDDQINQMDNHLQQLHMEHVELIAGAEEARKLVYTLRSKANDLEKEVERQKIAITEGAEEKREAIRQLCFSLEHYRNGYHRLRKAFVEHKRLPV 625          

Query:  577 KITVLETELSSVK-EKLQMRRLILNLSKHREN---EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            ++ V E  L   K + L++++   +L  H  +   +IA+LVA LE+ +E+LK SDDEI +LK EL  R S   H++QGQL+V QE +A LESQL  ERK + +L+ ++  Y A+    +  V +LK+ + DAQ QFSLEK  L +DI+ L+E+   L +R+EE   R+  +E++ R+ E +K+++E +   Q+M LQ EIS LK E+ +R   VEAVNK+FDR K K D++M EKDE NAK+H + A    R+N I  +E  +  L  +  ++  G  +  RLV ELKL+ + L+KEV  + V ISD AE+KREAIRQLCFS+EHYRSGYKEL QAF GH+  AV AA
Sbjct:  144 ELKVKEENLEYEKGQVLELQKKTADLETHVPDCSLKIAKLVAQLELAEEQLKISDDEIARLKEELNSR-SSGTHELQGQLEVAQEIVAALESQLVSERKQIHDLEGRVTWYKANETNTEHAVQKLKAKMLDAQAQFSLEKDLLHSDIARLSEENKQLGSRLEEYESRSNIIENKSRQLEAEKLKLEELLATQQMDLQGEISCLKEELDQRRHDVEAVNKEFDRHKQKCDVLMTEKDEANAKIHNLMAETRDRNNYIANLERDIILLRGQEAELSTGSAATLRLVKELKLKADGLEKEVILKNVMISDRAEEKREAIRQLCFSIEHYRSGYKELLQAFAGHKCHAVTAA 490          

Query:  577 KITVLETELSSVK-EKLQMRRLILNLSKHREN---EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            ++ V E  L   K + L++++   +L  H  +   +IA+LVA LE+ +E+LK SDDEI +LK EL  R S   H++QGQL+V QE +A LESQL  ERK + +L+ ++  Y A+    +  V +LK+ + DAQ QFSLEK  L +DI+ L+E+   L +R+EE   R+  +E++ R+ E +K+++E +   Q+M LQ EIS LK E+ +R   VEAVNK+FDR K K D++M EKDE NAK+H + A    R+N I  +E  +  L  +  ++  G  +  RLV ELKL+ + L+KEV  +   ISD AE+KREAIRQLCFS+EHYRSGYKEL QAF GH+  AV AA
Sbjct:  178 ELKVKEENLEYEKGQVLELQKKTADLETHVPDCSLKIAKLVAQLELAEEQLKISDDEIARLKEELNSR-SSGTHELQGQLEVAQEIVAALESQLVSERKQIHDLEGRVTWYKANETNTEHAVQKLKAKMLDAQAQFSLEKDLLHSDIARLSEENKQLGSRLEEYESRSNIIENKSRQLEAEKLKLEELLATQQMDLQGEISCLKEELDQRRHDVEAVNKEFDRHKQKCDVLMTEKDEANAKIHNLMAETRDRNNYIANLERDIILLRGQEAELSTGSAATLRLVKELKLKADGLEKEVILKNAMISDRAEEKREAIRQLCFSIEHYRSGYKELLQAFAGHKCHAVTAA 524          

Query:   10 MERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRR------LILNLSKHREN------EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQM-----------------------------QGQLQVVQEDIAMLESQL-----------------------------------HWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M+R E  KS S   D+  +P++S WL ENLEEMD+++K+MLKLI+ED DS  K  E Y + +PE   L+EEFYR YRSLA  YDH+T E  K + S +  QG G S++G +  S L +P+  ++  KS+++                   K+G                +S V+NY   +   +    G  ++I  LE EL  VKEKL  +        + +     EN      +I     +L +  E+L+ S++EI KL+ EL +  S ++  M                             + +L++ +E++   E+Q+                                   + E++   +LQE++ R    +  RD E+ +LK+A+ DA+++   EKA+L+A++S L E+QT L   I E   R ++ E++IR  +++K+EM       E  L++ I  LK E+ +R  +++ +N   D  KL       EKD LN +V ++  +++SRD +I  ++ HL  L+ EH  +I+  E A R V+E+K + + L+++V+ Q+  I + AE+KREAIRQLCFSLEHYR+ Y  L+Q F+GH+R  + AA
Sbjct:   12 MKRLESRKSHSWWWDSHISPKNSKWLFENLEEMDRNVKRMLKLIEEDADSFAKKAEMYYKKRPELVALVEEFYRGYRSLAERYDHVTGELRKNVQSDLQSQGSGFSDTGSEPPSTLPSPN--VTHRKSSNRAAGFDFFLGTGGNASDISQKDGEDESSTMTGSEDESD-DSSVNNY--SAFSRNGTDPGMNRRINELENELREVKEKLWTQEGEHAEVSVSSSGATHENADDVYAKINAYEQELMIVNEKLRLSEEEITKLRTELENYKSLDSRNMDVGVELEVEGSVDGVDKELFESSGGTASLREELRITKENLKASETQVASLNTEVNKSSDRIQQLKDQLDSAKKDVATWKTKFNSEKRESTKLQERLARLKTSLSDRDHEIRDLKTAVSDAEQKIFPEKANLKAEMSKLLEEQTHLKELIREWESRGRSFEEQIRNIQSEKIEM-------EAELKNGIQLLKAEIEQRENNIKDLNVSLDNLKL-------EKDNLNVEVGSLKEDVNSRDGRIGSLDRHLNDLHIEHVQLISSLEEACRQVEEIKTKAKNLEEQVERQKTEILEAAEEKREAIRQLCFSLEHYRNNYHMLKQHFIGHKRVPILAA 604          

Query:  589 LETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            LE E   V E  +    + N     +++I  L  +LE TK+RL GS++E  KLKHELT+ +S   HQ              LE Q H                       D EV  L +ALH+AQE FSLE+A LQ+DISSL+++  +L+TR+EE   +              +MEM+ +H AQE  L  EI  LK E++ER   V+A+NK+ D  K+ YD++MAEKDEL+A+V T+ A+++S DNQIQ++E HLR+L  E  ++IAG ESA +LVDEL  RV+EL++EV+ QRV ISD AE+KREAIRQLCFSLEHYRSGY+ELRQAF+GH+R  + A+
Sbjct:    6 LELEKRQVLELQKQTAELENRVSESDHKICMLEEELEETKKRLMGSEEENEKLKHELTNEISVVKHQ--------------LEDQHH-----------------------DREVESLNAALHNAQENFSLERAQLQSDISSLSKQVVLLETRLEEWRAK--------------EMEMKGLHEAQETVLLGEIEQLKAELSERGDIVQALNKNLDALKVTYDMLMAEKDELSARVDTLIADVNSWDNQIQQLEDHLRQLRIERVELIAGTESARKLVDELSWRVKELEREVERQRVVISDRAEEKREAIRQLCFSLEHYRSGYQELRQAFIGHKRLPILAS 294          

Query:    7 DMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARL--------------VADLEVTKERLKGSDDEIVKLKHELTHRLSEEA-HQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +++RTE +KS S   D+  +P++S WL +NLEEMDQS+K+MLKLI+EDGDS  K  E Y Q +PELI   E+FYR+YRSLA  YDH+T E  K + S +  QG G S+ G +  S   +PD +    KS  +                   K                  +S V+NYL          +  ++KI + E E+  +K +LQ +   LN + + + E+  L              V +L +TKERL+GS+ EI  L  EL  R S E+   MQ QL++  +DIAM +++L  E++ V +LQE++ RY   +  R+ E+ ELK  + DA   F LEK+ L A IS L + Q+ L+ +++E  LR ++LE+EI++ +T                           AE    +  +NK  D   LK+D +M+E+DEL+A+V                                                  E QK + S+       AE+KREAIRQLCFSLEHYR+ Y  LRQAF  H+R AV
Sbjct:  135 NLKRTESKKSHSWWWDSHISPKNSKWLADNLEEMDQSVKRMLKLIEEDGDSFAKKAEMYYQKRPELISHVEDFYRIYRSLAERYDHVTGELRKNILSDLQSQGSGISDLGSEPASTCPSPDQRERRRKSGRRAAGFDFFLGSGGSSSDLYNKGDESSSLSDSESGSD---DSSVNNYL--------GLRAAKEKIQLSEEEIVRLKTELQ-KYGPLNFTNNFQAELVELPPRDIKMQESELDLVEELRITKERLQGSEKEIATLIDELASRGSSESISHMQEQLELTHKDIAMWKAKLDREKREVSKLQERVGRYKTSLSDREHEIRELKEVISDADHNFELEKSLLMAKISKLLDDQSHLEEKLKEWELRCQSLEEEIKQADT---------------------------AESGDRINDLNKSLDALNLKHDTLMSERDELSARV--------------------------------------------------ERQKGLVSE------AAEEKREAIRQLCFSLEHYRNDYNRLRQAFTVHKRPAV 588          

Query:   10 MERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLH-KSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRR-------LILNLSKHRENEIARLVA---DLEVTKERLKGSDDEIVKLKHEL-THRL---------------------SEEAHQM-----------------QGQLQVVQEDIAMLESQLHWERKHVLELQ-------EKI--VRYSADIFGRDLEVMELK--------SALHDAQEQFSLEKADLQADISSLTEKQTILDTRI--EEGSLRNK---------NLEDEIR------RC-ETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M R E  KS S   D+  +P++S WL ENLEEMD+S+K+MLKLI+ED DS  K  E Y Q +PE   L+EEFYR+YR+LA  YDH+T E  K +PS +  QG G S++G +  S   +P  K     KS+ +                   K+G                +S V+NY       +    G  ++I  LETEL  VKEKL M+           + +++ E+   ++ A   +L    E+L+ S++EI K K EL  +RL                       EAH+M                  G+++ +  ++ + +  L      +  L+       E+I  +    ++  +D+   + K        + LH+   +     +D   +I  L  + +  + +I  E+  L+++         +LE++IR      RC E D   ++   +  E AL+ EI  LK  + +R  +++ +N   D  KL       EKD L+ +V ++   ++SRD +I+ +  HL  L+ EH  +IAG E AH+ V+ELK + ++L++EV+ QR  I +GAE+KREAIRQLCFSLEHYR GY  LRQ  +GHRR  V AA
Sbjct:    1 MRRLESRKSHSWWWDSHISPKNSKWLSENLEEMDRSVKRMLKLIEEDADSFAKKAEMYYQKRPELVALVEEFYRVYRALAERYDHVTGELRKNIPSDLQSQGSGISDAGSEPSSTWPSPTPKRGGRLKSSTRAAGFEYFLGSSGNGTDVYQKDGDESSTLTDSEEESD--DSSVNNY--SGFSRNGSDLGINRRIMELETELREVKEKLWMQEEEHADGSTRGSRNENTEDLYTKINAYEQELMTVNEKLRLSEEEITKQKIELQKYRLFNTENLEAGFESSLTKKHINEGGEAHKMIEVEGSIDGVDKELFDQNGEIETLARELRITKENLKASEMQITSLKFEANKSSERIQQLHDQLELARKDISTWKTKFNSEKRESTKLHERLARLRTSLSDRDHEIRDLKTEVSDAEQKIFPEKAQLKSEMSKVLEERTHLEEQIREWESRGRCFEDDIRRIQSEKMEMEEALKGEIQLLKAGIEQRENNIKELNTSIDTLKL-------EKDNLHVEVGSLKEEVNSRDGRIEHLNSHLNELHVEHVQLIAGMEEAHKHVEELKSKAKQLEEEVERQRTVILEGAEEKREAIRQLCFSLEHYRDGYNMLRQHVMGHRRVPVLAA 610          

Query:   22 EMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMR---------RLILNLSKHRENEIARLVA---DLEVTKERLKGSDDEIVKLKHEL-THRLSEEAHQMQGQL-QVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADL-----QADISSLTEKQTILDTRI-----EEGSLRNK---------NLEDEIRRCETDKMEMERMHVAQEMALQD--------------EIS-------------------------GLKVEVAERNGHVEAVNKDFDRFKLKYDI------VMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAA 1605
            +  KS S   D+  +P++S W  ENLEEMDQS+K+MLKLI+EDGDS  K  E Y Q +PELI   EEFYRMYRSLA  YDH+T+E  K +PS +  QG G S+  F+  SP    + K S  K   +                   +                  +S V+NY    L  +   QG  ++I  LE EL   KEKL+M+         R + N  +  E+ +A L     DL +  E L+ S++E+ +L  EL  +R SE +  +Q +     +  +   E +L +E      LQ++I    A+    ++++  L   L  A+E+  + + ++     Q +    +EK   L  ++     E  +L+NK          L++   R +T+  + +R     ++A+ D              EIS                         G+++  AE+    E + ++    KLK D       + +E+DELN K  T+ A ++SRDN + +M+ HL++L  EH  ++AG E A +L+DEL+ + ++L+ EV+ QR+ I +GAE+KREAIRQLC +LEHYR+ Y  LRQAF GH+   V A
Sbjct:   15 QTRKSHSWWWDSHISPKNSKWHTENLEEMDQSVKRMLKLIEEDGDSFAKKAEMYYQKRPELISHVEEFYRMYRSLAERYDHVTEELRKSIPSDLQSQGSGISDVIFEPPSP--ARELKPSRLKPGPRAAGFDFFLGSGGSGDRHHKEVDELSTLTDSESESD---DSSVNNY--SGLSGNSGDQGLSRRIIDLEIELRETKEKLRMQQDESVDGSFRGVRN--EDSEDVLAELTGCERDLTIANEELRLSEEEVTRLNTELQKYRSSEVSVGLQSEFASPAESKVTTREVELEFEVNQASHLQQRIGGSEAETLDSNVKIQALMEELRIAKERLHVSEKEITTLKKQLEGGGPSEKINNLQDQLALAHMEINTLKNKLNAEKREVSKLQERTARLKTNLSDRDREVRDLKIAVSDAELKIFPEKAQIKAEISKLIEEGTCLEERLKEQESRCRSLEDGIRMFQAEKAEMQETLEREIQ--KLKEDTAERDSRIKSERDELNEKAITLKAEVTSRDNPVNQMDKHLQQLRMEHVKLLAGAEEARKLMDELRSKAKDLEGEVERQRILILEGAEEKREAIRQLCLTLEHYRNSYHTLRQAFAGHKGVPVLA 612          

Query:  568 WQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIA--RLVADLEVTKERLKGSDDEIVKLKHELTHR--LSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHD---AQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            W +  T ++  L+S++ + ++      L+K RE  +A    + ++E  + +L     E ++L+ +L  +  L  EA +++ +L   +++   LE   H     V E +E+     A+       + EL+  L +   A+++  LEK   +A +  L E Q I++ +  + +   K LED +    TD ME E    ++ +A L+++   +  ++ ER    E   ++ ++ + K +    +  +L+ ++  + A ++    Q+ + E  L+   A  E+  A    A + + EL+ ++ ELQ++++S+R   +   +QKR+   +L
Sbjct:  827 WWRLFTKVKPLLNSIRHEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMA---EKLQLQEQLQAKTELCAEAEELRARLTAKKQE---LEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTDLMEEEEK--SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERACRNKAEKQKRDLGEEL 1141          

Query:  571 QQKITVLETELSSVKEKLQ------------MRRL---ILNLSKHRENEIARLVADLEVTKERLKGS-DDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLE-VMELKSALHDAQEQFSLEKADLQAD-------ISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN----GHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIR 1515
            +++I  L  +++ +K+K++             RRL   +  LS+  E ++A     LE TK RL+   DD +V L H+     + E  Q +    + +E      S  + E +   E + +     A    R LE  ME K+ L    +QF  E  DL +        +  L +    L+ ++EE   + + LEDE++  E  K+ +E    A +   + ++ G   +  E+       V  +  + +  + +  I MA + +L   +  + A++ + +   +E    LR+L A+ +D +   +      +E+  + +E +K++ S    +    E+   A R
Sbjct: 1357 EKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAY-DKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTI---SAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSNRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSIAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDVDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1695          

Query:  544 KVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            K   + Q  QQK T L  E + ++E+LQ                  L A+ E  + RL     E+ ++ HE+  RL EE  + Q QLQ  ++ +A          + +L+L+E++    A                  A+++  LEK   +A I  L +   ++D +  + S   K LE+ I    T+  E E    A+ +  L+++   +  E+  R    E   ++ ++ K K D    E  +L+ ++  + A ++    Q+ + E  L+   A  ED  +   +A + + EL+  + +LQ+++DS+R A +   +QKR+   +L
Sbjct:  870 KAESELQELQQKHTQLSEEKNLLQEQLQAE--------------TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ-QLQAERKKMA----------QQMLDLEEQLEEEEA------------------ARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK--AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMD---GEASDLHEQIADLQAQIAELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148          

Query:  562 QGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQ--EDIAMLESQLHWERKHVL-ELQEKIVRYSADIFGRDLEVMELKSALHDA-----------------QEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVA 1476
            Q  ++ I+ L  +LS  K+KLQ     +   +  +    + +  L    E    + D++ K K+ L   L +    +  Q Q+V   E       QL  E K++  +  ++  R  A+   ++ + + L  AL +A                  E     K D+  ++  L + +  L+T++EE   + + LEDE++  E  K+ +E    A ++  + ++         R+   E   +   R   +Y+  +  +DE   +     A         +++EG L+ L  + +  I G E A + + +L+ ++++ Q+E++  R +
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVESLEEGKKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKVQFERDLQA-------RDEQNEEKRRQLQRQLHEYETEL--EDERKQRALAAAAK--------KKLEGDLKDLELQADSAIKGREEAIKQLLKLQAQMKDFQRELEDARAS 1667          

Query:  595 TELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQ---MQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            TE+ +++ +L   +L L      E E   L A+ E  + RL     E+ ++ H+L  R+ EE  +   +Q + + +Q++I  LE QL  E                                  A+++  LEK   +A +  L E Q I++ +  + +   K LED I    T+ ME E    ++ +A L+++   +  ++ ER    E   ++ ++ + K +    +  +LN ++  + A ++    Q+ + E  L+   A  E+       A + + EL+ ++ ELQ++++S+R + +   +QKR+   +L
Sbjct:  869 TEMETLQSQLMAEKLQLQEQLQAETE---LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES--------------------------------ARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRIAEFTTNLMEEEEK--SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLNDQIAELQAQIAELKMQLAKKEEELQAALARVEEEATQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141          

Query:  571 QQKITVLETELSSVKEKLQ---------------MRRLILNLSKHRENEIARLVADLEVTKERLKGS-DDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLE-VMELKSALHDAQEQFSLEKADLQAD-------ISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN----GHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIR 1515
            +++I  L  +++ +K+K++               +++ +  L +  E ++A     LE TK RL+   DD +V L H+     + E  Q +    + +E      S  + E +   E + +     A    R LE  ME K+ L    +QF  E  DL +        +  L + +  L+ ++EE   + + LEDE++  E  K+ +E    A +   + ++ G   +  E+       V  +  + +  K +  + +A + +L   +  + A++ S +    E    LR+L A+ +D +   +      +E+  + +E +K++ S    +    E+   A R
Sbjct: 1356 EKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRKLQKDLEGLGQRYEEKVAAY-DKLEKTKTRLQQELDDLLVDLDHQRRTASNLEKKQKKFDQLLAEEKTI---SAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDEKKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCVRELDDTRASREEILAQAKENEKKMKSMEAEMIQLQEELAAAER 1694          

Query:  595 TELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQ---MQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            TE+ +++ +L   +L L      E E   L A+ E  + RL     E+ ++ H+L  R+ EE  +   +Q + + +Q++I  LE QL  E                                  A+++  LEK   +A +  L E Q I++ +  + +   K LED +    T+ ME E    ++ +A L+++   +  ++ ER    E   ++ ++ + K +    +  +L+ ++  + A ++    Q+ + E  L+   A  E+  A    A + + EL+ ++ ELQ++++S+R + +   +QKR+   +L
Sbjct:  869 TEMETMQSQLMAEKLQLQEQLQAETE---LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEES--------------------------------ARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTNLMEEEEK--SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERASRNKAEKQKRDLGEEL 1141          

Query:  571 QQKITVLETELSSVKEKLQ------------MRRL---ILNLSKHRENEIARLVADLEVTKERLKGS-DDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLE-VMELKSALHDAQEQFSLEKADLQAD-------ISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN----GHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIR 1515
            +++I  L  +++ +K+K++             RRL   +  LS+  E ++A     LE TK RL+   DD +V L H+     + E  Q +    + +E      S  + E +   E + +     A    R LE  ME K+ L    +QF  E  DL +        +  L + +  L+ ++EE   + + LEDE++  E  K+ +E    A +   + ++ G   +  E+       V  +  + +  + +  + MA + +L   +  + A++ + +   +E    LR+L A+ +D +   +      +E+  + +E +K++ S    +    E+   A R
Sbjct: 1356 EKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAY-DKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTI---SAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694          

Query:  571 QQKITVLETE------LSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQ 1569
            QQ +  L+ E      L  +  KL+ +   L  S  +E    +L ADLE  K++L+G     +KL  E    L  +  Q++ +L+  + +I+ L++++  E+ H L+LQ+KI    A I   + E+   +++   A++Q S    +L+     L E   +   ++E     NK  E E ++   D  E    H A   AL+ + +    E+ E+  +++ V +  ++ K +  +   E D+L + + TV+ + S+ +   + +E     + A+ +          +L+ +L ++   LQ    +Q   +S   E+K   I QL    +      +EL++
Sbjct: 1008 QQALDDLQVEEDKVNGLIKINVKLEQQTDDLEGSLEQEK---KLRADLERIKKKLEGD----LKLSQESIMDLENDKQQVEEKLKKKEFEISQLQTKIDDEQVHSLQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEASGVTSAQVE----MNKKREAEFQKLRRDLEEATLQHEATTAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKM---EIDDLASNIETVSKSKSNVERMCRTVEDQFNEIKAKDDQQT-------QLIHDLNMQKARLQ----TQNGELSHQLEEKESLISQLTKGKQALTQQLEELKR 1321          

Query:  595 TELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQ---MQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            TE+ +++ +L   +L L      E E   L A+ E  + RL     E+ ++ H+L  R+ EE  +   +Q + + +Q++I  LE QL  E                                  A+++  LEK   +A +  L E+Q IL+ +  + +   K LED I    T+  E E    ++ +A L+++   +  ++ ER    E   ++ ++ + K +    +  +L+ ++  + A ++    Q+ + E  L+   A  E+  A    A + + EL+ ++ ELQ++++S+R + +   +QKR+   +L
Sbjct:  869 TEMETLQSQLMAEKLQLQEQLQAETE---LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES--------------------------------ARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK--SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141          

Query:  571 QQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGS-DDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLE-VMELKSALHDAQEQFSLEKADLQAD-------ISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN----GHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIR 1515
            +  +  LET    VK KLQ  + +  LS+  E ++A     LE TK RL+   DD +V L H+     + E  Q +    + +E      S  + E +   E + +     A    R LE  ME K+ L    +QF  E  DL +        +  L + +  L+ ++EE   + + LEDE++  E  K+ +E    A +   + ++ G   +  E+       V  +  + +  + +  + +A + +L   +  + A++ S +    E    LR+L A+ +D +   +      +E+  + +E +K++ S    +    E+   A R
Sbjct: 1374 EDSVGCLETA-EEVKRKLQ--KDLEGLSQRHEEKVAAY-DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI---SAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694          

Query:  571 QQKITVLETE------LSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQ 1569
            QQ +  L+ E      LS +K KL+ +   L  S  +E    +L  DLE  K +L+G     +KL  E    L  +  Q+  +L+    + + L+S++  E+   L+LQ+KI    A I   + E+   ++     ++Q S    +L+     L E   +  T+IE     NK  E E  +   D  E    H A    L+ + +    E+AE+  +++ V +  ++ K ++ +   E D+L++ V +V+ + ++ +   + +E  L     ++E+M        R + EL  +   LQ E       +S   E+K   + QL  S + +    +EL++
Sbjct: 1005 QQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLESSLEQEK---KLRVDLERNKRKLEGD----LKLAQESILDLENDKQQLDERLKKKDFEYSQLQSKVEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIE----LNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQKLEKEKSEFKL---EIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEEM-------QRSLSELTTQKSRLQTEAGE----LSRQLEEKESIVSQLSRSKQAFTQQIEELKR 1318          

Query:  571 QQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            ++K T +E EL  ++ K Q      N+   +      L A+ E  + RL     E+ ++ H+L  R+ EE  + Q           +L+++    + H+ +L+E++          D E          A+++  LEK   +A I  + E+  +L+ +  +     K +ED I  C +   E E    A+ +A ++++   +  ++ ER    E   ++ ++ K K D    E  +L  ++  + A +     Q+ + E  L+   A  +D      +A ++V EL+ ++ ELQ++ +S++ + +   +QKR+   +L
Sbjct:  865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQ-----------ILQNEKKKMQAHIQDLEEQL----------DEE--------EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK--AKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD---GETTDLQDQIAELQAQIDELKIQVAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148          

Query:  571 QQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSD---DEIVKLKHELTHRLSEEAHQMQGQLQVVQ--EDIAMLESQLHWERKHV-LELQEKIVRYSADIFGRDLEVMELKSALHDA-----------------QEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN----GHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAI 1479
            ++++  L+ +L+  K+K+      L   ++ E    +L+ D+EV  +RL+      D++ K K  L   L +    +  Q Q+V   E       QL  E K++     E+  R  A+   ++ + + L  AL +A                  E     K D+  ++  L + +  L+ ++EE   + + LEDE++  E  K+ +E    A +   + ++     +  E+       V  +  + +  + +  + +A K ++   +  + A + + +    E+   LR+L A+ +D     E A    DE+  + +E +K++ S    I
Sbjct: 1363 EKQLQALQAQLTDTKKKVDDD---LGTIENLEEAKKKLLKDVEVLSQRLEEKALAYDKLEKTKTRLQQELDDLLVDLDHQRQIVSNLEKKQKKFDQLLAEEKNISARYAEERDRAEAEAREKETKALSLARALEEALEAREEAERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEI 1689          

Query:  595 TELSSVKEKL-QMRRLILNLSKHR---ENEIARLVADLEVTKE-------RLKGSDDEIVKLKHELTH------RLSEEAHQMQGQLQVVQ--------------EDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEE--GSLRN---------KNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN---GHVEAVNKDFD-----------RFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISD 1485
            T L  + E+L Q +R   NL K++   E +   L  +++V ++       + K  D ++ +L  +++        L+E+A+++Q +L  V               +D A LESQL    +   EL ++  R   ++  R  ++ E +S+L + QE+    +  L+  + +L  + T    ++++  G++ N         K++E   +R E   +  +++    +  LQ E+  L V++  +     ++E   K FD           R+  + D   AE  E   K  ++   L       +E E   ++L A+ ED+++  +   + V EL+     L+++V+  R  + +
Sbjct: 1203 TALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQL----QDTQELLQEETRQKLNLSSRIRQLEEERSSLQEQQEEEEEARRSLEKQLQALQAQLTDTKKKVDDDLGTIENLEEAKKKLLKDVEVLSQRLEEKALAYDKLE-KTKTRLQQELDDLLVDLDHQRQIVSNLEKKQKKFDQLLAEEKNISARYAEERDRAEAEAREKETKALSLARALEEALEAREEAERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550          

Query:  604 SSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAM--------------LESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHD---AQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            + VK  LQ+ R        +E E+     +L+ TKER + +++E+ +L+ + + +L+EE + +Q QLQ   E  A               LE  LH     + E +++  +  A+      ++++L+  L +   A+++  LEK   +A I  L ++  ++D +  + S   K LE+ I    T+  E E    A+ +  L+++   +  E+  R    E   ++ ++ K K +    +  + + ++  + A ++    Q+ + E  L+   A  +D IA   +A + + EL+  + +LQ+++DS+R A +   +QKR+   +L
Sbjct:  839 TKVKPLLQVTR--------QEEEMQAKEDELQKTKERQQKAENELKELEQKHS-QLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK--AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE---GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148          

Query:  592 ETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEE---AHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLK--VEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDN---QIQEMEGHLRRLNAEHEDMIAGYESAHR----LVDELKLRVEELQKEVDSQRVAISDGAEQKRE 1506
            E EL  +++K        NL + +      L A+ E  + RL     E+ ++ HE+  RL EE     Q+Q + + + + +  LE QL  E     +LQ + V   A I   + E++     + D   + S E+  L+  IS LT       T + E   + KNL     + E+   E+E + + +E   + E+  LK  +E    + H +  +      +LK  +   E +EL A +  +   ++ ++N   +I+E+EGH+  L  + +   A    A +    L +EL+    EL+  +DS   A       KRE
Sbjct:  872 ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL----VMDDQNNKLSKERKLLEERISDLT-------TNLAEEEEKAKNLTKLKNKHESMISELE-VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE-EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS--TATQQELRAKRE 1173          

Query:  562 QGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQ--EDIAMLESQLHWERKHVL-ELQEKIVRYSADIFGRDLEVMELKSALHDA-----------------QEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVA 1476
            Q  ++ I+ L  +LS  K+KLQ     +   +  +    + + +L    E    + D++ K K+ L   L +    +  Q Q+V   E       QL  E K++  +  ++  R  A+   ++ + + L  AL +A                  E     K D+  ++  L + +  L+T++EE   + + LEDE++  E  K+ +E        AL+ +      ++  R+   E   +   R   +Y+  +  +DE   +     A         +++EG L+ L  + +  I G E A + + +L+ ++++ Q+E++  R +
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE----VNMQALKGQFER---DLQARDEQNEEKRRQLQRQLHEYETEL--EDERKQRALAAAAK--------KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS 1667          

Query:  571 QQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            ++K T +E EL  ++ K Q      N+   +      L A+ E  + RL     E+ ++ H+L  R+ EE  + Q           +L+++    + H+ +L+E++          D E          A+++  LEK   +A I  + E+  +L+ +  +     K +ED I  C +   E E    A+ +A ++++   +  ++ ER    E   ++ ++ K K D    E  +L  ++  + A +     Q+ + E  L+   A  +D      +A ++V EL+ ++ ELQ++ +S++ + +   +QKR+   +L
Sbjct:  865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQ-----------ILQNEKKKMQAHIQDLEEQL----------DEE--------EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK--AKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD---GETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148          

Query:  571 QQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSD---DEIVKLKHELTHRLSEEAHQMQGQLQV---VQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDA---QEQFSLEKADLQAD--------------ISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN----GHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAI 1479
            ++++  L+++L+  K+K+      L   +  E    +L+ D E   +RL+      D++ K K+ L   L +    +  Q QV   +++     +  L  E+       E+  R  A+   ++ + + L  AL +A   +E+F  +   L+AD              +  L + +  L+ ++EE   + + LEDE++  E  K+ +E    A +   + ++     +  E+       V  +  + +  + +  + +A K ++   +  + A + + +    E+   LR+L A+ +D     E A    DE+  + +E +K++ S    I
Sbjct: 1363 EKQVLALQSQLADTKKKVDDD---LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEI 1689          

Query:   13 ERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLN--SPVSNYLVPSLKVHFDSQ-GWQQKITVLETELSSVKEKLQMRR-LILNLSKHREN-------------------------------EIARLVADLEVTKERLKGSDDEIVKLKHELT--HRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +R+  +KS S   D+ N P++S WL ENLE+MD  +  MLKLI+ED DS  K  + Y Q +PELI   EEFYRMYR+LA  YD  + E  K   S I       S+S  +  SP      KLS  +S+H+                    N                L         L+    V  D+      KIT  E EL    EK++M    I NL    ++                               ++  L  +L + KE+L+  + E   LK+EL       E+   +Q +L++ Q D     ++L+ E+K VL+LQE++      +  RD E+  LK+A+ DA+++   EKA ++ ++S + E+++ L  ++ E       LE  IR  + +K E E     +     ++ISG++                               DE N     +   +  R+ +I+E E H+  L+ E                 L+ R  EL +EV+  RV+ S+ AEQKREAIRQLC SL+HYR GY  L +   GH+ + V
Sbjct:   13 KRSMTKKSHSWWWDSHNCPKNSKWLAENLEKMDDRVNHMLKLIEEDADSFAKKAQMYFQKRPELIQLVEEFYRMYRALAERYDQASGELQKNHTSEI------QSQSSLEISSPTKE---KLSRRQSSHKEEEDSSSLTDSGSDSDHSSANDEDGDEALIRRMAELELELQETKQKLLLQQESVDGDNNVDLLHKITTYEGELKEANEKMRMHEDEIANLKNQLQSFMSFDTEDHLGAEQKSVDLDKEDTKEDAVATKVLALEEELSIAKEKLQHFEKETYSLKNELEIGKAAEEKLKSLQHELELAQRDADTYINKLNAEKKEVLKLQERLAMVKTSLQDRDNEIRALKTAVSDAEQKIFPEKAQIKGEMSKMLEERSQLGEQLRE-------LESHIRLIKEEKAETEE----KLRGGTEKISGMR-------------------------------DESNV----LREEIGKREEKIKETEKHMEELHMEQV--------------RLRRRSSELTEEVERTRVSASEMAEQKREAIRQLCMSLDHYRDGYDRLWRVVAGHKSKRV 512          

Query:   13 ERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLN--SPVSNYLVPSLKVHFDSQ-GWQQKITVLETELSSVKEKLQMRR-LILNLSKHREN-------------------------------EIARLVADLEVTKERLKGSDDEIVKLKHELT--HRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +R+  +KS S   D+ N P++S WL ENLE+MD  +  MLKLI+ED DS  K  + Y Q +PELI   EEFYRMYR+LA  YD  + E  K   S I       S+S  +  SP      KLS  +S+H+                    N                L         L+    V  D+      KIT  E EL    EK++M    I NL    ++                               ++  L  +L + KE+L+  + E   LK+EL       E+   +Q +L++ Q D     ++L+ E+K VL+LQE++      +  RD E+  LK+A+ DA+++   EKA ++ ++S + E+++ L  ++ E       LE  IR  + +K E E     +     ++ISG++                               DE N     +   +  R+ +I+E E H+  L+ E                 L+ R  EL +EV+  RV+ S+ AEQKREAIRQLC SL+HYR GY  L +   GH+ + V
Sbjct:   13 KRSMTKKSHSWWWDSHNCPKNSKWLAENLEKMDDRVNHMLKLIEEDADSFAKKAQMYFQKRPELIQLVEEFYRMYRALAERYDQASGELQKNHTSEI------QSQSSLEISSPTKE---KLSRRQSSHKEEEDSSSLTDSGSDSDHSSANDEDGDEALIRRMAELELELQETKQKLLLQQESVDGDNNVDLLHKITTYEGELKEANEKMRMHEDEIANLKNQLQSFMSFDTEDHLGAEQKSVDLDKEDTKEDAVATKVLALEEELSIAKEKLQHFEKETYSLKNELEIGKAAEEKLKSLQHELELAQRDADTYINKLNAEKKEVLKLQERLAMVKTSLQDRDNEIRALKTAVSDAEQKIFPEKAQIKGEMSKMLEERSQLGEQLRE-------LESHIRLIKEEKAETEE----KLRGGTEKISGMR-------------------------------DESNV----LREEIGKREEKIKETEKHMEELHMEQV--------------RLRRRSSELTEEVERTRVSASEMAEQKREAIRQLCMSLDHYRDGYDRLWRVVAGHKSKRV 512          

Query:   10 MERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDA--KLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMR-----RLILNLSKHRENEI---ARLVA---DLEVTKERLKGSDDEIVKLKHELT-----------------------HRLSEEAH-------------------------------QMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGH 1584
            ++R E  KS+    D+    ++S WL  NL+EMD+S+K+M+KLI+ED DS  K  E Y Q +PELI   +EF+RMYR+LA  Y+++T E  K  P  +  QG G S+      S L T +   +L    S  +                   K+G                +S V+NY    + +  D Q   ++I  LE EL   KE+L+M+       +L   K     +   A+L A   +L+   E+L+ S+D+I  LK +L                          LSEE                                  +Q  L+  Q++ A  +S+   +++ V++L ++I    + + GRD E+ +LK+AL DA+E+   EKA ++ADI+ L E++   D + +E     + LEDE R+   +K+E       +E  L+ EI  L +E  E+   +E +++              +  EL +++  + + + +RD++  EME                                   KEV+ QR  + + AE+KRE IRQLCFSL++ R  YK LR AF GH
Sbjct:   12 IKRVESTKSNPWWWDSHIGLKNSKWLENNLDEMDRSVKRMVKLIEEDADSFAKKAEMYYQSRPELIALVDEFHRMYRALAERYENITGELRKGSPLELQSQGSGLSDISASDLSALWTSNEVNRLGRPPSGRRAPGFEYFLGNGGLPSDLYHKDGDDSASITDSELESD--DSSVTNY-PGYVSIGSDFQSLSKRIMDLEIELREAKERLRMQLEGNTESLLPRVKSETKFVDFPAKLAACEQELKDVNEKLQNSEDQIYILKSQLARYLPSGLDDEQSEGAASTQELDIETLSEELRITSLRLREAEKQNGIMRKEVEKSKSDDAKLKSLQDMLESAQKEAAAWKSKASADKREVVKLLDRISMLKSSLAGRDHEIRDLKTALSDAEEKIFPEKAQVKADIAKLLEEKIHRDDQFKELEANVRYLEDERRKVNNEKIE-------EEEKLKSEIEVLTLEKVEKGRCIETLSR--------------KVSELESEISRLGSEIKARDDRTMEME-----------------------------------KEVEKQRRELEEVAEEKREVIRQLCFSLDYSRDEYKRLRIAFSGH 547          

Query:  691 DLEVTKERLKGSDDEIVKLKH-ELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEV------------------------DSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQ 1593
            +L  T  +L+  + EI KLK  E    +      ++G+ ++ Q +IA+ +  +  ERK VLE+Q ++V         + E+ +L         +  + +  L    S +++ + +L    +  S+    L D+I+  E +KMEM+R    +E+ LQ EIS LK ++A R  H+EA+NKDFD+ KL+YD++MAEKD + A+V  + A + SRD QIQ+ME  L +L  +  ++++   +A   V+ELK  V+EL+ EV                        + QR AIS G E+KREAIRQLCFSL+HY+SGYK+L     G+ +Q
Sbjct:  111 ELRTTSLKLQEFEQEIEKLKETEKKESVVLFGEYLRGEREIAQGEIAIRDIAIETERKRVLEVQRQVVDL-------ETELSDLSFKFEHLVNEHEVSRDCLDVSFSEISKLREMLCDCQQNFSIEKTKLVDQIKHSEAEKMEMQR----KEVELQAEISALKTDLATRGEHIEALNKDFDKHKLRYDMLMAEKDGVCAEVDNLKAEMRSRDIQIQQMEEQLNQLVYKQTELVSESGNAKNTVEELKAVVKELEIEVELQSKAKKTVEELRATVWEMEKHAELQRNAISQGEEEKREAIRQLCFSLDHYKSGYKQLLWYLSGNNQQ 425          

Query:  691 DLEVTKERLKGSDDEIVKLKH-ELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEK-QTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEV------------------------DSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQ 1593
            +L  T  +L+  + EI KLK  E    +      ++G+ ++ Q +IA+ +  +  ERK VLE+Q ++V                                DL+ ++S L+ K + +++   +  S+    L D+I+  E +KMEM+R    +E+ LQ EIS LK ++A R  H+EA+NKDFD+ KL+YD++MAEKD + A+V  + A + SRD QIQ+ME  L +L  +  ++++   +A   V+ELK  V+EL+ EV                        + QR AIS G E+KREAIRQLCFSL+HY+SGYK+L     G+ +Q
Sbjct:  111 ELRTTSLKLQEFEQEIEKLKETEKKESVVLFGEYLRGEREIAQGEIAIRDIAIETERKRVLEVQRQVV--------------------------------DLETELSDLSFKFEHLVNEHEQNFSIEKTKLVDQIKHSEAEKMEMQR----KEVELQAEISALKTDLATRGEHIEALNKDFDKHKLRYDMLMAEKDGVCAEVDNLKAEMRSRDIQIQQMEEQLNQLVYKQTELVSESGNAKNTVEELKAVVKELEIEVELQSKAKKTVEELRATVWEMEKHAELQRNAISQGEEEKREAIRQLCFSLDHYKSGYKQLLWYLSGNNQQ 401          

Query:   10 MERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDA--KLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPS-LKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA--------------------LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMI-AGYESAHRLVDELK-LRVEELQK----EVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGH 1584
            ++R E  KS+    D+    ++S WL  NL+EMD+S+K+M+KLI+ED DS  K  E Y Q +PELI   +EF+RMYR+LA  Y+++T E  K  P  +  QG G S+      S L T +   +L    S  +                   K+G                +S V+NY  P  + +  D Q   ++I  LE EL   KE+L+M+                L  + E    R+K S+ + V    +L     +E   +  +LQ  ++ I +L+SQL               RY             L S L D Q + +    +L  DI +L+E+  I   R+ E   +N  +  E+ + ++D  +++ +    E A                    L D IS LK  +A R+  +  +       + K   +  EK ++ A +  +      RD+Q +E+E ++R L  E   +     E   +L  E++ L +E+++K    E  S++V+  +    +   IRQLCFSL++ R  YK LR AF GH
Sbjct:   12 IKRVESTKSNPWWWDSHIGLKNSKWLENNLDEMDRSVKRMVKLIEEDADSFAKKAEMYYQSRPELIALVDEFHRMYRALAERYENITGELRKGSPLELQSQGSGLSDISASDLSALWTSNEVNRLGRPPSGRRAPGFEYFLGNGGLPSDLYHKDGDDSASITDSELESD--DSSVTNY--PGYVSIGSDFQSLSKRIMDLEIELREAKERLRMQ----------------LEGNTESLLPRVK-SETKFVDFPAKLA-ACEQELKDVNEKLQNSEDQIYILKSQL--------------ARY-------------LPSGLDDEQSEGAASTQEL--DIETLSEELRITSLRLREAEKQNGIMRKEVEKSKSDDAKLKSLQDMLESAQKEAAAWKSKASADKREVVKLLDRISMLKSSLAGRDHEIRDLKTALSDAEEK---IFPEKAQVKADIAKLLEEKIHRDDQFKELEANVRYLEDERRKVNNEKIEEEEKLKSEIEVLTLEKVEKGRCIETLSRKVSELESEISRLGMIRQLCFSLDYSRDEYKRLRIAFSGH 514          

Query:  106 MDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDA--KLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMR-----RLILNLSKHRENEI---ARLVA---DLEVTKERLKGSDDEIVKLKHELT-----------------------HRLSEEAH-------------------------------QMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNK 1221
            MD+S+K+M+KLI+ED DS  K  E Y Q +PELI   +EF+RMYR+LA  Y+++T E  K  P  +  QG G S+      S L T +   +L    S  +                   K+G                +S V+NY    + +  D Q   ++I  LE EL   KE+L+M+       +L   K     +   A+L A   +L+   E+L+ S+D+I  LK +L                          LSEE                                  +Q  L+  Q++ A  +S+   +++ V++L ++I    + + GRD E+ +LK+AL DA+E+   EKA ++ADI+ L E++   D + +E     + LEDE R+   +K+E       +E  L+ EI  L +E  E+   +E +++
Sbjct:    1 MDRSVKRMVKLIEEDADSFAKKAEMYYQSRPELIALVDEFHRMYRALAERYENITGELRKGSPLELQSQGSGLSDISASDLSALWTSNEVNRLGRPPSGRRAPGFEYFLGNGGLPSDLYHKDGDDSASITDSELESD--DSSVTNY-PGYVSIGSDFQSLSKRIMDLEIELREAKERLRMQLEGNTESLLPRVKSETKFVDFPAKLAACEQELKDVNEKLQNSEDQIYILKSQLARYLPSGLDDEQSEGAASTQELDIETLSEELRITSLRLREAEKQNGIMRKEVEKSKSDDAKLKSLQDMLESAQKEAAAWKSKASADKREVVKLLDRISMLKSSLAGRDHEIRDLKTALSDAEEKIFPEKAQVKADIAKLLEEKIHRDDQFKELEANVRYLEDERRKVNNEKIE-------EEEKLKSEIEVLTLEKVEKGRCIETLSR 432          

Query:   52 DNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLT---KEAHKIMPSVIPVQG---------FGDSESGFDHGSPLMTPDAKL-----SLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQ---GWQQKITVLETELSSV--KEKLQMRRLILNLSK--HRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERM---HVAQEMALQ---DEISGLKVEVAERNGHVEAVNKDFDR--FKLKYD-----IVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRL 1362
            D+  +P++S WL ENL +MD  +KQM+K+I+ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   + A + M    P Q           G S  GFD  +P   P  +       L K A  +                  ++ +                + V    + + KV  +S+     + +I  L+  LS V  +++  + +   NL K  + E+E++R   D  V  ER   ++ E+  L+  L+ ++  E      Q Q   ++IA LE ++   +K   E+ E+  R  A       E + LK +L  ++          Q  + +++  +  L    E+  L N+  E+     E+ K ++ ++   + A E+  Q   D I+ LK+++       + ++++ +    KLK+      ++      L++++  +   L ++ +++ E +  L RL
Sbjct:   17 DSHISPKNSKWLQENLTDMDSKVKQMIKVIEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATGVIRHAQQTMAEAFPNQDPMMFGEESPLGSSTDGFDPQTPDSYPPIRAPVYPDDLRKGAFGISSSHLSTVKRNIAFMEDPQSVSSGKGFKTAKARKGLNFNNVDGKEI-NAKVLSESERASKAEAEIVALKDALSKVQAEKEASLAQFDQNLEKLSNLESEVSRAQEDSRVLIERATRAEAEVETLRESLS-KVEVEKESSLLQYQQCLQNIADLEDRISLAQKEAGEVDERANRAEA-------ETLALKQSLVSSETDKEAALVQYQQCLKTISNLEERLHKAEEDSRLTNQRAENAEGEVESLKQKVSKLIEENEAYELQYQQCLDTIADLKLKLFHAQEETQRLSREIEDGVAKLKFAEEKCVVLERSNQNLHSELDGLLEKLGNQSHELTEKQKELGRL 484          

Query:  562 QGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERL-----------KGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHW-ERKHVLELQE-KIVRYSADIFGRDL-EVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            Q  QQ  +  + ELS++  +LQ R  IL   + R N +   V + +   + L           K   +E+ KL+ E   +L  E      Q   +Q++I  L+ +L    +KH   +++ ++V    + FG  + E+ E  S L + +E+ S+EK       ++L EK  +++  +++  L   ++ D     ET + +++ +  A  M+L +E SGL  E       +++  ++    KL  + ++ E    NA V      L    ++++ +E     LN +   + +  ES    +D ++ R+E+L+KE    +V + + A ++  +++++
Sbjct:  503 QTLQQLHSQSQEELSTLALELQNRSQILKDMEARNNGLQEEVQEAKDQSKSLNELNLSSAASIKSLQEEVSKLR-ETIQKLEAEVELRVDQRNALQQEIYCLKEELSQIGKKHQSMVEQVELVGLHPESFGSSVKELQEENSKLKEIRERESIEK-------TALIEKLEMMEKLVQKNLLLENSISDLNAELETIRGKLKTLEEAS-MSLAEEKSGLHSEKDMLISRLQSATENSK--KLSEENMVLENSLFNANVE-----LEELKSKLKSLEESCHLLNDDKTTLTSERESLLSHIDTMRKRIEDLEKEHAELKVKVLELATERESSLQKI 820          

Query:   67 PESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKE---AHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMR-RLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFG-------RDLEVMELKSA---LHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQ---DEISGLKVEVAERNGHVEAVNKDF--DRFKLK-----YDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGY---ESAHRLVDELKLRVEELQKEVDSQ 1467
            P++S W+ +NL +MD  +K M+KLI+ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T E   AHK M    P      ++  FD     M  D+  S                          K G                 S ++ YL  S     +++    K T++E  L + KE L ++ +L LN       + +RL  DLEV ++ + G D+   K + E T  L+E   +++      + D A+L  + +   + + EL+E       D+ G        + EV  LK A   LH  +E    E       IS+L +K    +   +  S ++   EDEI+    + +++  +     +  Q   + IS L+ EV+    + + ++ +      KLK       ++ +  + L  +   +T  L+++D +I + +  L +  +  ED  + Y   E + + +  L  + +E QK + S+
Sbjct:   22 PKNSKWIQQNLSDMDSKVKAMIKLIEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATVELCHAHKTMAEAFP------NQVPFD-----MIEDSASSSCSEPRTPEKMPPGIQPFYDSDSATSKRGL----------------SQLTEYLGNS-----ETEVESLKRTLVE--LGAEKEALNLQYQLSLN-------KFSRLEKDLEVAQKDVSGLDERASKAEIE-TKILAEALAKLE-----AERDAALL--RYNESMQKITELEESFSHAQEDVKGLTNRATKAETEVENLKQAHSRLHSEKEAGLAEYNRCLEMISNLEKKVRDAEENAQNFSNQSAKAEDEIKALRHELVKVNEVKDGLRLRYQQCLETISKLEREVSHAQDNAKRLSSEVLAGAAKLKTVEDQCTLLESSNETLKLEADGLTHKLAAKDQEIFQKQNELEKFQSLIEDEHSRYLEIEVSLKTLQSLYSQSQEEQKVITSE 469          

Query:  574 QKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKE-------RLKGSDDEIVKLKHELTH------RLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQF---SLEKADLQADISSLTEKQTILDTRIEE--GSL-----RNKNLEDEIRRCETDKMEMERMHVAQEMALQD---EISGLK-------VEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDM--IAGYESAHR--LVDELKLRVEELQKEVDSQRVAIS-----DGAEQKREAIRQLCFSL 1533
            + I+ LE ++   +E  Q      N S   E+EI  L  +L    E       R +   + I KL+ E++H      RLS E      +L+ V++   +LES     +     L  K+     +IF +  E+ + +S + D   ++    +    LQ+  S   E+Q ++ + ++   G L     RN  LE +I   + +   +  ++ +  + L+    EIS LK        EVA       A  ++  R K        E D LN +   +   ++      + +   +R+L  E+  +  +  ++S  +  L ++L+     L+K V  +++ +      DG+ +K + +++ C SL
Sbjct:  300 EMISNLEKKVRDAEENAQN---FSNQSAKAEDEIKALRHELVKVNEVKDGLRLRYQQCLETISKLEREVSHAQDNAKRLSSEVLAGAAKLKTVEDQCTLLESSNETLKLEADGLTHKLAAKDQEIFQKQNELEKFQSLIEDEHSRYLEIEVSLKTLQSLYSQSQEEQKVITSELQSRIGMLRDLETRNLKLEGDISSVKEENQNLSELNDSSMIFLETQKCEISSLKEIKEKLEEEVARHINQSSAFQEEIRRLK-------DEIDSLNKRYQAIMEQVNLAGLDPKSLACSVRKLQDENSKLTELCNHQSDDKDALTEKLRELDNILRKNVCLEKLLLESNTKLDGSREKTKDLQERCESL 651          

Query:   52 DNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAHK-------IMPSVIPVQGFGDSESG------FDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQG-----WQQKITVLETELSSVKEKLQMRRLILNLSKHR----ENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQ---EQFSLEKADLQADISSLTEK-------QTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDR--FKLKYD-----IVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRL----NAEH---EDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQL 1521
            D+ N P++S WL +NL +MD ++KQM+K+++ED DS  +  E Y + +PE   L+EEFYR YR+LA  Y+H T   HK         P+ +P+  FGD   G       D  +P M P  +   +    Q                    +                 N          LK H  S+       + ++  L+  LS ++ + Q    +   +  R    E+E++R  AD     +R   ++ EI  L+ E  ++L  E      Q     + IA LE  L    K   E   K           + E + LK +L  A+   E   ++       IS+L E+         +++ R E+  +  +NL+  + +   DK   E     Q     + I+ LKV++       ++++ + +    KLK+      ++      L++++ ++   L ++  ++ E +  L +L     AEH   ++    +++  +L  + +  +  L  E+ +    + D   +  E   +L
Sbjct:   18 DSHNTPKNSKWLQDNLADMDSNVKQMIKVLEEDADSFARRAEMYYRKRPELMKLVEEFYRAYRALAERYNHATGVIHKAHETIAEAFPNQVPLI-FGDESHGGALTNDVDPQTPDMPPPFRARGNPDEFQQDALGFSLSHVHDVKRNIDFSEEPLFVSNGKARKGLNFNDHGDGKGRNGLKDHILSESERASKAEAEVVALKDSLSKMQAEKQASLALFEKNLERLSNLESEVSRAQADSRGINDRAASAEAEIQTLR-ETLYKLESEKESSFLQYHKCLQKIADLEDGLSVAHKEAGERASK----------AETETLALKRSLAKAETDKETALIQYRQCLNTISNLEERLRKAEEDARLINERAEKAGVEVENLKQTVSKLIKDKEASE----LQFQQCLNIIASLKVKLHHAQEETQSLSHEIEDGVAKLKFSEEKCLLLERSNQNLHSELDSLLEKLGNQSQKLTEKQTELVKLWSCVQAEHLHFQEAETAFQTLQQLHSQSQEELNNLAVELQTVSQIMKDMEMRNNELHEEL 540          

Query:  106 MDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQM-----RRLILNLSKHRENE--IARLVA---DLEVTKERLKGSDDEIVKLK-----------------------------------------HELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M++S+KQMLKLI+EDG SL K  E   Q +P+LI   +EF  M +SLA CY+++T E    +PS   VQG  +SESG  H  PL+TPD KL  HK++++                   K G+               NS  + Y   SL V+ D     +KI V+ T+LSS++EKL+M     R  +LN  ++R  E  ++R++    +L +TK +L+ S+D++ +LK                                          EL  +++E + ++QGQL+V +E+I ML ++L+ E + VL+LQE+I  Y +D+   D E+     AL DAQE  S+EKA LQ++I  L+EKQ +L+ ++ E  L+ K +ED++R+CE +KM+M+ +H AQE+ALQ EIS LKVE+ +R  HVE +NK FD  K KYD++MAEKD ++AKV+T+ A+++SRDNQI++MEGHL++L+ EHE +IAG +S+ +LVDEL+L+V EL+KEVD QRV +S  AE+KR AIRQLCFSLEHYRSGYKELR+AFLGH+R +V A+
Sbjct:    1 MERSVKQMLKLIEEDGVSLAKKAEMCRQTRPDLISKIKEFNSMQQSLAECYEYVTTELTNSIPSEFDVQGVDNSESGHGHDPPLLTPDQKLGFHKASNRA----PSVSSHGASSDLSLKEGSESFSFSSSDSESESFNSSGNAYY--SLPVNTDRSELHKKIIVMGTDLSSMEEKLRMHEEENRDSMLNGEENRNYEELLSRIIGYEEELRLTKVKLQLSEDDVTRLKIELEKSVFFRDLSGTLQAQLELALKDIQMREDDLQVERKRVLELQKKVAEGSEELQGQLKVAEEEITMLNAKLNTESRRVLDLQERITCYKSDLSDHDHEI----KALKDAQENHSVEKAHLQSEILDLSEKQNMLEVKLREWDLQGKFMEDKLRQCEAEKMQMKNLHDAQEIALQGEISQLKVELIDRGEHVEVLNKKFDSLKSKYDMLMAEKDGMSAKVNTLIADVNSRDNQIRQMEGHLQQLHTEHEKLIAGSQSSRKLVDELRLKVVELEKEVDGQRVELSAVAEEKRAAIRQLCFSLEHYRSGYKELREAFLGHKRHSVMAS 545          

Query:   22 EMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMR---------RLILNL-SKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTH-RLSEEAHQMQGQL-QVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADL-----QADISSLTEKQTILDTRI-----EEGSLRNK---------NLEDEIRRCETDKMEMERMHVAQEMALQD--------------EIS-------------------------GLKVEVAERNGHVEAVNKDFDRFKLKYDI------VMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAA 1605
            +  KS S   D+  +P++S W  ENLEEMDQS+K+MLKLI+EDGDS  K  E Y Q +PELI   EEFYRMYRSLA  YDH+T+E  K +PS +  QG G S+  F+  SP    + K S  K   +                   +                  +S V+NY    L  +   QG  ++I  LE EL   KEKL+M+         R + N  S+    EI     DL +  E L+ S++E+ +L  EL   R SE +  +Q +     +  +   E +L +E      LQ++I    A+    ++++  L   L  A+E+  + + ++     Q +    +EK   L  ++     E  +L+NK          L++   R +T+  + +R     ++A+ D              EIS                         G+++  AE+    E + ++    KLK D       + +E+DELN K  T+ A ++SRDN + +M+ HL++L  EH  ++AG E A +L+DEL+ + ++L+ EV+ QR+ I +GAE+KREAIRQLC +LEHYR+ Y  LRQAF GH+   V A
Sbjct:   15 QTRKSHSWWWDSHISPKNSKWHTENLEEMDQSVKRMLKLIEEDGDSFAKKAEMYYQKRPELISHVEEFYRMYRSLAERYDHVTEELRKSIPSDLQSQGSGISDVIFEPPSP--AREQKPSRLKPGPRAAGFDFFLGSGGSSDHHHKEVDELSTLTDSESESD---DSSVNNY--SGLSGNSGDQGLSRRIIDLENELRETKEKLRMQQDESVDGSFRGVRNEDSEDVLAEITGCERDLTIANEELRLSEEEVTRLNTELQKCRSSEVSDGLQSEFASPAESKVTTREVELEFEVNQASHLQQRIGGSEAETLDSNVKIQALMEELRIAKERLHVSEKEITTLKKQLEGGGPSEKINNLQDQLALAHKEINTLKNKLNAEKREVSKLQERTARLKTNLSDRDREVRDLKLAVSDAELKIFPEKAQIKAEISRLIEEGTCLEERLKEQESRCRSLEDGIRMFQAEKAEMQETLEREIQ--KLKEDTAERDSRIKSERDELNEKAITLKAEVTSRDNPVNQMDKHLQQLRMEHVKLLAGAEEARKLMDELRSKAKDLEGEVERQRILILEGAEEKREAIRQLCLTLEHYRNSYHTLRQAFAGHKGVPVLA 612          

Query:  670 EIARLVADLEVTKERLKGSDDEIVKLKHELT-HRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAA 1605
            +I  L+ +L +  ERLK S+ EI  LK +L     S++ + +Q +L +  ++I  L+ +L+ E++ V +LQE+I R  + +  RD E  +LK A+ DA+++   EKA ++A++S L E++T L+ +++E   R ++LED+IR  + +K EME+        L  EI  LK +VAER+ H+E ++K  D       ++ +E+DELN KV  + A ++SRD +I +M+ HL++L+ EH  +++G E A +L+D L+ +V++L++EV+ QR  I +GAE+KREAIRQLC +LEHYR+ Y  LRQAF+GH+R  V A
Sbjct:  324 KIQSLMKELRIANERLKVSEKEITTLKGQLEGDGPSDKINNLQDELALAHKEINTLKKKLNAEKREVSKLQERISRLKSSLSDRDHEARDLKIAVSDAEQKIFPEKAQIKAEMSKLIEERTCLEEQLKEQESRGRSLEDDIRMFQAEKAEMEQR-------LDCEIQQLKEDVAERDNHIEKMDKSLD-------VLKSERDELNVKVIALKAEVTSRDERIDQMDRHLQQLHMEHVKLVSGAEEARKLMDVLRSKVKDLEEEVERQRFVILEGAEEKREAIRQLCLALEHYRNDYHTLRQAFVGHKRVPVLA 622          

Query:   64 NPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLT---KEAHKIM----PSVIPVQGFGDSESGFDHGSPLMTPDAKL--------SLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQG----WQQKITVLETELSSVKEKLQMRRL-ILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHR------LSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDS--QRVAI-SDGAEQKREAIRQLCFSLEHYRSGYKELRQAF 1575
            +P++S WL ENL  MD  +KQM+KL++ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   ++AH+ M    P+ +P+    DS +G        TPD            L K A  V                  + G                           L  H   +     W      L+  + S  E++    L IL L    +N +A+L A+ E    R + S + +  L+ E++        L+E A + + ++  ++E +A LE++   ++   L+ Q  + + S ++      V +     ++   +  +E   L+ D++ L  ++ ++  + ++   +  +LED++   + D                          +ER G  E   ++ D  K     +  EK+    +     A + S +++I   E   RRLN+E +D     + A      L    + +Q E++S  Q+VA  S+   +K++ + +L   ++  R  + E   AF
Sbjct:   22 SPKNSKWLQENLTGMDFKVKQMIKLLEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATGALRQAHRTMAEAFPNQVPLMLGDDSPAGSATDGDPRTPDMPPIRAPFDPDELQKDALGVSPSHRNGAFTEESDSVPGRKGLKQLNDLFGSGDGVNHAKFSEGRARKGLSFHDPEEKEQGVWNDSSHDLKARIPSQSERVSQAELEILTL----KNALAKLEAEKEADLLRYENSLERLSNLESEVSRATEDSRGLNERASKSEAEVLTLKEALAELEAE---KKSSFLQYQHCLEKIS-NLENSISHVQKDAGEQNERAGKAEIEAQSLKQDLARLEAEKNVVLVQYKQCLEKISDLEDQLLNAQEDARRF----------------------SERAGDAE---REIDTLKQALTKLTEEKEAAVTQYQQCLATIVSLEHKITCFEEEARRLNSEIDDGAVKLKDAEERCILLVKSNQTMQSELESLVQKVAAQSEEVTEKKKELGRLWTCVQEERLRFIEAETAF 524          

Query:   64 NPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLT---KEAHKIM----PSVIPVQGFGDSESGFDHGSPLMTPDAKL--------SLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQG----WQQKITVLETELSSVKEKLQMRRL-ILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHR------LSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDS--QRVAI-SDGAEQKREAIRQLCFSLEHYRSGYKELRQAF 1575
            +P++S WL ENL  MD  +KQM+KL++ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   ++AH+ M    P+ +P+    DS +G        TPD            L K A  V                  + G                           L  H   +     W      L+  + S  E++    L IL L    +N +A+L A+ E    R + S + +  L+ E++        L+E A + + ++  ++E +A LE++   ++   L+ Q  + + S ++      V +     ++   +  +E   L+ D++ L  ++ ++  + ++   +  +LED++   + D                          +ER G  E   ++ D  K     +  EK+    +     A + S +++I   E   RRLN+E +D     + A      L    + +Q E++S  Q+VA  S+   +K++ + +L   ++  R  + E   AF
Sbjct:   22 SPKNSKWLQENLTGMDFKVKQMIKLLEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATGALRQAHRTMAEAFPNQVPLMLGDDSPAGSATDGDPRTPDMPPIRAPFDPDELQKDALGVSPSHRNGAFTEESDSVPGRKGLKQLNDLFGSGDGVNHAKFSEGRARKGLSFHDPEEKEQGVWNDSSHDLKARIPSQSERVSQAELEILTL----KNALAKLEAEKEADLLRYENSLERLSNLESEVSRATEDSRGLNERASKSEAEVLTLKEALAELEAE---KKSSFLQYQHCLEKIS-NLENSISHVQKDAGEQNERAGKAEIEAQSLKQDLARLEAEKNVVLVQYKQCLEKISDLEDQLLNAQEDARRF----------------------SERAGDAE---REIDTLKQALTKLTEEKEAAVTQYQQCLATIVSLEHKITCFEEEARRLNSEIDDGAVKLKDAEERCILLVKSNQTMQSELESLVQKVAAQSEEVTEKKKELGRLWTCVQEERLRFIEAETAF 524          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLT---KEAHKIMPSVIPVQ----GFGDSESGF--DHGSP-----------LMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQ--EDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELK---SALHDAQEQFSLEKADLQADISSLTEK-------QTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAE-------KDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQ 1569
            M  +  +E  +  S   D+  +P++S WL ENL +MD  +K M+KLI+ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   ++AH+ M    P Q       DS SG     G P            + PD    LH+ +  +                  K                 ++      +   LKVH   +  + ++ +L+  LS ++ + +   L    S  + + + R + D+    ER   ++ EI  LK  L      EA +  G LQ  +  E I+ LE+ +    +    L E+ ++        ++E   LK   SAL   +E   L+       +SSL +K         +L+   E      K LE  + +    K E E   +  E+ L ++I+ ++ E+      V  +N +      K   V  +          L ++   +   ++++D ++ E E  L +L A  +D     +S    V+     +++L  +   ++ A++   + + + ++ L  S    +   +++++
Sbjct:   51 MATLLHSESRRLYSWWWDSHISPKNSKWLQENLTDMDAKVKAMIKLIEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATVELRQAHRTMAEAFPNQVSYAPGDDSPSGSFGPDGEPHTPEMPHPICAFLDPD---GLHRDSFGLSMERNGGYPEESDSGINKKGLKQLDELFMSREAASQVSKVADGKMKKGLKVH---EAAETEVQILKKALSEIQTEKEAALLQYQQSLQKLSSLERELKDVGGLDERASRAEIEIKILKETLA---KLEAERDAGLLQYNKCLERISALENVISQTEEDSKGLNERAIK-------AEIEAQHLKQELSALEAEKEAGLLQYNQCLQLLSSLRKKIFIAEENSRMLNELTERAETEAKALEKALAKL---KEEKEAAELQYELCL-EKIAMMESEIFHAQEDVNRLNSEILTGAAKLKTVEEQCFLLERSNHSLQSEAENLAQKIATKDQELLEKENELEKLQASLQD----EQSRFIQVEATLQTLQKLHSQSQEEQKALAFELQNRLQILKDLEISNHDLQENLQQVKE 591          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLT---KEAHKIM----PSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQV-VXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSN-YLVPSLKVHFDSQ-----GWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQ--EDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALH--DAQEQFSLEK--------ADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDK----------MEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISD 1485
            M  +  +E  +  S   D+  +P++S WL ENL +MD  +K M+K+I+ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   ++AH+ M    P+ +P     DS SG         P+ +    +  H +                   K G                 S V++  L   LK+H  ++       + ++ +++  LS ++ + +   L    S  + + + R + D     ER   ++ EI  LK  L   +  EA +  G LQ  +  E I+ LE+ +    +    L E+ ++        ++E   LK  L   +A+++ SL +         +LQ  I    E   +L+   E      K L++ + +   +K          +E   M  ++    Q++++ L  E+      ++ V +     +     + +E D L  K+ T    LS + N++++++  L+   ++   + A   S  +L  + +     L  E+ +    + D
Sbjct:    1 MATLLHSESRRLYSWWWDSHISPKNSKWLQENLTDMDAKVKAMIKVIEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATVELRQAHRTMAEAFPNQVPYVLVDDSPSGSS------GPEGEPHSLEMPHPIRAFLDPDDLRMDSLGLSINKTGLKQLNELFGSRDAVSQVSKVADGKLKKCLKIHEAAEVDTGKQAETEVQIIKKALSEIQTEKEAVLLQYQQSLQKLSSLERELNDFRGIDERAGKAEIEIKILKETL---VKLEAERDAGLLQYNKCLERISALENVISKMEEDAKGLNERAIK-------AEIEAQNLKQELSGLEAEKEASLLQYNQCLELIFNLQKKILIAEENARMLNALTETAETEAKALKEALAKLSEEKEAAELQYELCLEKIAMMESEVSHAQEDVNRLNSEILSGTAKLKTVEEQCFLLQRSNQSLQSEADTLVQKIETKDQELSEKVNELEKLQASLQDEQSQFIQVEATLHSLQKLHSQSQEEQRALAIELQNHFQMLKD 518          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAH-------KIMPSVIPVQGFGDSESGFDHGSPLMTPD 360
            M    + + ++  S   D+  +P++S WL ENL +MD  +KQM+KLI+ED DS  +  E Y + +PE   L+EEFYR YR+LA  YDH T   H       +  P+  P     DS +G        TPD
Sbjct:    1 MAARSQADSKRKYSWWWDSHISPKNSKWLQENLTDMDSKVKQMIKLIEEDADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHATGALHQAQRTMAEAFPNQAPFILGDDSPAGSATDCDPRTPD 130          

Query:  517 VSNYLVPSLKVHFDSQGWQQKITVLE--------TELSSVKEK--LQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFS--LEK-ADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDK---MEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNA---EHEDMIAGYESAHRLVDELKLRVEELQKEVDSQ---RVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFL 1578
            V N  +  LK    S+  Q     LE         +L + KE   LQ  + +  LSK  E+E++R   D     ER   ++ E+  LK E+  +L  E      Q Q   E I+ LE+ L   +K   EL E+  +   +      ++  L++   DAQ Q+S  LEK + L+  + +  E       R ++     + L+  + R   +K   +   +  +A  ++L+ +I+  + E    N  ++         + +  ++      +++++ +V   ++++ N++ E +  L RL A   E        E+A + +  L  + +E  + V +Q   R  I +  E + ++++     +EH +   K L +  L
Sbjct:  212 VQNNGIHDLKARAPSESEQVSKAELEILNLKNALAKLEAEKEAGLLQYEQSLERLSK-LESEVSRATEDSRGLNERASKAEAEVQALK-EVLAQLEAEKESSFLQYQGCLEKISNLENNLSLVQKDAGELNERASKAETEARSLKQDLSRLEAEKIDAQVQYSQCLEKISHLEGKLHNAQEDAKRFSERADDAEREIEALKHALTRLTEEKEAAVTQYQQCLATIVSLEHKIACFEEEARRLNLVIDDGTVKLKSSEERCLLLEKSNQTIHSELESVMQKVAAQSNELTEKQKELGRLWACVQEEHLRFMEAETAFQTLQHLHSQSQEELRSVVAQLQNRAQILEDLEARNQSLKD---EVEHVKVENKSLSEVNL 582          

Query:   76 SIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKE---AHKIMPSVIPVQ-GFGDSESGFDHGSP-LMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHF-DSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIA---MLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELK---SALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMA-----LQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNA-------EHEDMIAGYESAHRLVDELKLRVEELQ--KEVDSQRVAISDGAEQKREAIRQLCFSLEHYRS 1548
            S WL ENL++M++ +  MLK+I+  GD+  +  E Y + +PELI   E+ YR YR+LA  +DHL+KE   A++ + +V P Q  F   +  F+   P +   D     HK +   +                 K  +                    N    S K +   S G  ++      E +   +KLQ   L L   K     ++      E  + +  G +++I +++  ++    E      G   V+ ++ A   M  + L   +  +++LQEK          R+L   E K     + + Q+++   K +  +D S L E     +   E+    + NL  E  + E +  +++  H   ++A     L +++  L+  V+ ++  V  +  D D   L+  I   E+D+      T+  N     N+++E+E   RR+         ++++++     A   +D L ++++ ++  KEV+ +      GA    +A R +    EH  S
Sbjct:   23 SKWLEENLQDMEEKVNNMLKIIENSGDTFAQRAEMYYRRRPELINHVEDSYRAYRALAERFDHLSKELQSANRTIATVFPEQVQFAMDDDDFEESDPTIFESDDPNEAHKVSKANI----------------PKVPSMPKKDFRNQTMLLSRKGQQLNRTASSAKANVPPSSGLSRE------EAAEKTDKLQKEILALQTEKEFVQSVS------ERCQAKCGGIENQITEMQVTISGLQDE-----FGISNVIDDNEARTLMAATALKSCKDTLVKLQEK----------RELSAEEAKVENRRIKEVQQKYVALKGEFLSDQSDLLEPADEQEAESEDIDPNDTNLLREKIKGELE-ADLKSSHTVMQLAERIDELVEKVVNLETAVSSQDALVNRLKSDSD--GLQTHIKTLEEDKA-----TLMENSEKMSNKLRELEEEFRRVKCLNENIKDQNKNLLTRLTEASCAIDHLSVKLQTVKPDKEVEKEESIQESGAAVDVKAGRGVEEQEEHLAS 491          

Query:  559 SQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELK----SALHDAQ------EQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEM---ALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVE 1440
            +QG + +I  LE E+ S     ++  L+  L ++     +R    L V  + L      I   K EL  ++    ++   +++ + + + +L+ QL   R   +EL+ ++   + +I    + +  LK    S   D Q      E  S +  DL+ ++ +L  ++T L  +I   +   + L +E+ R +   +EME+    +E    ALQ+  +  ++E + +   + A+ +  +    + D +  EK+++  ++       S    +++  +  L    AEH  M+   E AH+ ++E   +VE
Sbjct: 1230 NQGLEARI--LELEMMSKVRGDELSALMKKLEENYNESFSR-TESLTVQVDTLLADFKSIHAQKAELEEQMVSRGNEASTRVEGLIDQVNLLQQQLESLRSQKVELEVQLENKTLEISEYRILIENLKEEIVSKTEDQQRVLAEKESCSAQINDLELEVETLCNQKTDLGEQISTETKERERLGEEMVRLQEKILEMEKTQTEREFELSALQERHTNGEIEASAQ---IMALTEQVNNLHQELDSLQTEKNQMQLQLEKEKEEFSENLTEMENQKSELVSQIAEHRRMLDEQEEAHKKLNEEHKQVE 1530          

Query:  574 QKITVLETELSSVK-EKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKL---KHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERN----GHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQ 1569
            +++  L  EL S++ EK QM+   L L K +E E +  + ++E  K  L     E  ++   + E   +L+EE  Q++G  Q  +  +A+ E ++          Q+    +   +  RD  V +L+  + D +    + K D   ++++L E    ++ ++   + + +  E  +   E    + E  +  ++  L++ ++ L   +   N      V  +++  +   L  D +  + +E   +       +S    +I   +      N E+E +    E+  + +++L+ +V  L+  +  +   I D  E+KREAIRQLC  +E+++S Y  LR+
Sbjct: 1457 EQVNNLHQELDSLQTEKNQMQ---LQLEKEKE-EFSENLTEMENQKSELVSQIAEHRRMLDEQEEAHKKLNEEHKQVEGWFQECKLSLAVAERKV----------QDMAEEFQKHLGSRDQMVEQLEEMIEDLKRDLEV-KGD---ELNTLVENVRNIEVKLRLSNQKLRVTEQLLTENEDTFRKAEEKYQQEQRVLEERVAVLSGIITANNEAYHSMVADISEKVNNSLLGLDALTMKFEEDCNRYENCILVVSK---EILIAKNWFGDTNNENEKLRKEKENLTKAINQLEKKVVALETMMKEKDEGILDLGEEKREAIRQLCIWIEYHQSRYDYLRE 1775          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPE--SSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSK------------------HRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            MVDMERTE+++SDS G DN   P+  +S+WLVENLEEMDQ IKQM KLIKEDGDSLPK  E + Q KPEL+EEF+RMYRSLAGCY+HLTKE HK         G GDSE GFD GSPL+TPDAK  LHKS HQVV                 KNG+              LNSPVSNYLVP     FDSQGWQQKIT LETELSSV+EKLQMR   L + K                   RENEI RL+ DLEVTKER KG D EIVKLK E  HR+SE AHQMQG           LE QL  ERKHV EL+E+IVRY+ DI G DLEVM+LKSALHDAQEQFSLEKA+LQADISS +EKQ +LDTR+EE S ++K+L+DEIR+CE DKMEMER+HV +EMALQDEIS LKVEVA+RNGHVEAVNKDFDRFKLKYD++MAEKDELNA+  T+ AN+SSRDNQIQEM GHL  L  EHE +I G E AHRLVDELK RVEELQ+EV+ Q V ISDGAE+KRE IRQLCFSLEHYRSGY+ELRQAF GHRR+ VAAA
Sbjct:    1 MVDMERTELKESDSTGLDNGITPDRSTSMWLVENLEEMDQRIKQMXKLIKEDGDSLPKNDEAFYQKKPELVEEFHRMYRSLAGCYEHLTKEXHK---------GLGDSEYGFDQGSPLLTPDAKHGLHKSGHQVVGLGISPSSDGSSPALSLKNGSESSSSSSLGSESESLNSPVSNYLVPPPNDDFDSQGWQQKITELETELSSVREKLQMREXDLKMEKMRVFELQNQXVELESLASDRENEIXRLLGDLEVTKERRKGLDKEIVKLKDEHAHRISEGAHQMQG-----------LEXQLDLERKHVSELEERIVRYNXDILGXDLEVMQLKSALHDAQEQFSLEKANLQADISSFSEKQVLLDTRVEELSFKSKSLDDEIRQCEADKMEMERLHVVREMALQDEISRLKVEVADRNGHVEAVNKDFDRFKLKYDMLMAEKDELNARAQTLMANVSSRDNQIQEMAGHLSLLRTEHEGLIFGSECAHRLVDELKSRVEELQQEVNRQSVVISDGAEEKREVIRQLCFSLEHYRSGYQELRQAFTGHRRRVVAAA 536          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPE--SSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSK------------------HRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            MVDMERTE+++SDS G DN   P+  +S+WLVENLEEMDQ IKQM KLIKEDGDSLPK  E + Q KPEL+EEF+RMYRSLAGCY+HLTKE HK         G GDSE GFD GSPL+TPDAK  LHKS HQVV                 KNG+              LNSPVSNYLVP     FDSQGWQQKIT LETELSSV+EKLQMR   L + K                   RENEI RL+ DLEVTKER KG D EIVKLK E  HR+SE AHQMQG           LE QL  ERKHV EL+E+IVRY+ DI G DLE            EQFSLEKA+LQADISS +EKQ +LDTR+EE S ++K+L+DEIR+CE DKMEMER HV +EMALQDEIS LKVEVA+RNGHVEAVNKDFDRFKLKYD++MAE DELNA+   + AN+SSRDNQIQEM GHL     EHE +I G E AHRLVDELK RVEELQ+EV+ Q V ISD AE+KRE IRQLCFSLEHYRSGY+ELRQAF GHRR+AVAAA
Sbjct:    1 MVDMERTELKESDSTGLDNGITPDRSTSMWLVENLEEMDQRIKQMXKLIKEDGDSLPKNDEAFYQKKPELVEEFHRMYRSLAGCYEHLTKEXHK---------GLGDSEYGFDQGSPLLTPDAKHGLHKSGHQVVGLGISPSSDGSSPALSLKNGSESSSSSSLGSESESLNSPVSNYLVPPPNDDFDSQGWQQKITELETELSSVREKLQMREXDLKMEKMRVFELQNQXVELESLASDRENEIXRLLGDLEVTKERRKGLDKEIVKLKDEHAHRISEGAHQMQG-----------LEXQLDLERKHVSELEERIVRYNXDILGXDLE------------EQFSLEKANLQADISSFSEKQXLLDTRVEELSFKSKSLDDEIRQCEXDKMEMERXHVVREMALQDEISRLKVEVADRNGHVEAVNKDFDRFKLKYDMLMAEXDELNARAQXLMANVSSRDNQIQEMAGHLSLXRTEHEGLIFGSECAHRLVDELKSRVEELQQEVNRQSVVISDAAEEKREVIRQLCFSLEHYRSGYQELRQAFTGHRRRAVAAA 524          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSK------------------HRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            MVDMERTE++KSDS G DN+ +P+SS+WLVENLEEM QSIKQM+KLIKEDGDSLP   E + Q KPEL++EF RMYRSLAGCY HL K AHK         GFGDSE GF+ GSPL+TPDAK  L KS  QVV             X   K G                NSPVSNYLVP     FDSQGWQ KI  LETELS +KEKLQ++   L + K                   R+NEI +L+ DLEVTKERLKGSD EI  LKHEL  R+S+ A QMQG           +ESQL  ERK V ELQE+IVR +ADIFGRDLEVM+LKSAL +AQEQFSLEKADLQADISS   KQ +LDTR+EE SLRNK LEDEI++CETDKMEMER+H   EMALQD+IS LKVEVA++NGHVEAVNKD D FKLK D++MAEKDELNA+  T+ AN+SSRDNQIQEM GHL RL  EHE +I G ESA RLVDELK RVEELQ+EV  Q V ISDGAE+KRE IRQLCFSLEHYR GY+ELRQAF GHR++ V
Sbjct:    1 MVDMERTELKKSDSAGLDNSISPDSSMWLVENLEEMGQSIKQMMKLIKEDGDSLPNKDETFLQKKPELVQEFQRMYRSLAGCYQHLNK-AHK---------GFGDSEYGFNQGSPLLTPDAKHGLRKSDDQVVGFDISLSSDGSSPXLTLKXGAESSSSSSLGSESDSPNSPVSNYLVPPPSADFDSQGWQLKIAELETELSXLKEKLQVKESDLTMEKMRVFELQEQIVELENRASDRDNEIRKLMEDLEVTKERLKGSDKEIANLKHELADRISKGADQMQG-----------VESQLDSERKLVSELQERIVRCNADIFGRDLEVMQLKSALREAQEQFSLEKADLQADISSFAAKQIVLDTRLEELSLRNKGLEDEIKQCETDKMEMERLHAVYEMALQDDISSLKVEVADKNGHVEAVNKDLDIFKLKCDMLMAEKDELNARAQTLMANVSSRDNQIQEMAGHLSRLQTEHEGLIVGSESACRLVDELKTRVEELQQEVKRQSVVISDGAEEKREVIRQLCFSLEHYRRGYQELRQAFTGHRQRLV 530          

Query:  295 PVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSK------------------HRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQ 1593
            P       E GF+ GSPL+TPDAK  L KS  QVV                 KN                 NSPVSNY VP     F+SQGWQQKI  LETELSS+KEKLQ++   L + K                   R+NEI +L+ DLEVTKERLKGSD+EI  LKHEL  R+S+ A QMQG           +ESQL  ERKHV EL E+IVR +ADIFG +LEVM+LKSALHDAQEQFSLEKADLQADISS   K+ +LDTR+EE SLRNK LEDEIR+CETDKMEMER+H   EMALQD+IS LKVEVA++NGHVEAVN+D D FKLKYD++MAEK+ELN +  T+ AN+SSRDNQIQEM GHL RL  E E +I G ESA RLVDELK RV ELQ+EV  Q V ISDGAE+KRE IRQLCFSLEHYRSGY+ELRQAF GHR++
Sbjct:   10 PFPPLSQHEYGFNQGSPLLTPDAKHGLRKSDDQVVGFDISLSSDGSSPALSLKNSAESSSSSSLGSESDSPNSPVSNYSVPPPSADFNSQGWQQKIAKLETELSSLKEKLQVKESDLTMEKMRVFELQEQIVELENRASDRDNEIRKLMEDLEVTKERLKGSDEEIANLKHELDDRISKGADQMQG-----------VESQLDSERKHVSELPERIVRCNADIFGCELEVMQLKSALHDAQEQFSLEKADLQADISSFAAKRIVLDTRLEELSLRNKRLEDEIRQCETDKMEMERLHAVYEMALQDDISRLKVEVADKNGHVEAVNEDLDMFKLKYDMLMAEKNELNGRAQTLMANVSSRDNQIQEMAGHLSRLQTEREGLIVGSESARRLVDELKTRVGELQQEVKRQSVVISDGAEEKREVIRQLCFSLEHYRSGYQELRQAFTGHRQR 449          

Query:  787 QMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +++ +L  ++E + + ES L  E+  V ELQE+IV        RD E+ +L   L   QE+              L  KQ +LDTR+EE SLRNK LEDEIR+CETDKMEMER+H   EMALQD+IS LKVEVA++NGHVEAVN+D D FKLK D++MAEKDELN +  T+ AN+SSRDNQIQEM GHL RL  EHE +I G ESA RLVDELK RVEELQ+EV  Q V ISDGAE+KRE IRQLCFSL+HYRSGY+ELRQAF GHR++ V
Sbjct:  165 ELETELSXLKEKLQVKESXLTMEKMRVFELQEQIVXLENRASDRDNEIRKLMEDLEVTQER--------------LKAKQIVLDTRLEELSLRNKRLEDEIRQCETDKMEMERLHAVYEMALQDDISRLKVEVADKNGHVEAVNEDLDMFKLKCDMLMAEKDELNGRAQTLMANVSSRDNQIQEMAGHLSRLQTEHEGLIVGSESACRLVDELKTRVEELQQEVKRQSVVISDGAEEKREVIRQLCFSLDHYRSGYQELRQAFTGHRQRLV 421          

Query:   10 MERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSK------------------HRENEIARLVADLEVTKERLKGSDDEIVKLKHELT---HRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHV---LELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVE 1209
            MERTE++KSDS G DN+ +P+SS+WLVENLEEM QSIKQM+KLIKEDGDS P   E + Q KPEL++EF RMYRSLA CY HL K AHK         GFGDSE GF+ GSPL+TPDAK   H  +   +                 K G                NSPVSNYLVP     FDSQGWQ KI  LETELS +KEKLQ++   L + K                   R+NEI +L+ DLEVT+ERLK     +     EL+    RL +E  Q +               ++  ER H    + LQ+ I R   ++  ++  V     A+++  + F L+   L A+   L  +   L   +     + + +   + R +T   E E + V  E A +  +  LK  V E    V+
Sbjct:    1 MERTELKKSDSAGLDNSISPDSSMWLVENLEEMXQSIKQMMKLIKEDGDSXPNKXETFLQKKPELVQEFQRMYRSLAXCYQHLNK-AHK---------GFGDSEYGFNQGSPLLTPDAK---HDGSSPPL---------------TLKXGAESSSSSSLGSESDSPNSPVSNYLVPPPSADFDSQGWQLKIAELETELSXLKEKLQVKESXLTMEKMRVFELQEQIVXLENRASDRDNEIRKLMEDLEVTQERLKAKQIVLDTRLEELSLRNKRLEDEIRQCE-------------TDKMEMERLHAVYEMALQDDISRLKVEVADKNGHV----EAVNEDLDMFKLKCDMLMAEKDELNGRAQTLMANVSSRDNQIQEMAGHLSRLQT---EHEGLIVGSESACR-LVDELKTRVEELQQEVK 375          

Query:  103 EMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPD---AKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHEL-THRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAA 1605
            EMD+SIK+MLKL++EDGD+  K  E Y Q +PELI   EEFYR+YRSLA  YDH+  E  K  PS +  Q    S+ G +  S L +PD    +L   KS  +                   K G                +S V+NY  P                                     LS    ++I  L  +L  TK+RL+ S+ EI  L+ +L +++ SEE  ++QGQL    +DI+  +++ + E++ V +LQE+I R    +  RD EVM+LK A+ DA+E+   EKA ++A+IS L  ++T  + +I++   R + LEDEIRR ++ K EME         L  EI+ LK ++ ER+  +E +NK  D  K        E+ EL+ K  T+ A +SSRD++I E+   L+ +  EH++++ G E   +LV+EL  R +EL++E+  QR+ I +GAE KREAIRQLCFSLEHYR+ Y  LRQA +G++R  V A
Sbjct:   14 EMDRSIKRMLKLVEEDGDTFAKKAEMYYQKRPELIAHVEEFYRLYRSLAERYDHVIGELRKNAPSDLQSQSSCLSDIGSELPSALPSPDFQPGRLGRRKSGPRAAGFDFFLGPGGNGSDNYQKEGDESSSLTDSEPESD--DSSVNNYSTP-------------------------------------LSNDPGSKIEALTKELRATKDRLQHSEKEIASLRQQLESNKASEEIQRLQGQLVSANKDISSWKTKFNAEKREVSKLQERISRLKNSLTDRDNEVMDLKIAVSDAEEKIFPEKAQVKAEISRLQLERTHSEEQIKDWESRARLLEDEIRRMKSGKAEMEE-------RLNGEIAQLKADILERSNQMENLNKVLDAMK-------TERYELSTKATTLQAEVSSRDDRINEINKTLQHMQTEHQELLNGAEGERKLVEELTERXKELEEEIQXQRIVIMEGAEGKREAIRQLCFSLEHYRNEYHRLRQACMGNKRVPVLA 468          

Query:  832 LESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVE 1440
            +ESQL  ERK V ELQE+IVR +ADIFGRDLEVM+LKSAL +AQEQFSLEKADLQADISS   KQ +LDTR+EE SLRNK LEDEI++CETDKMEMER+H   EMALQD+IS LKVEVA++NGHVEAVNKD D FKLK D++MAEKDELNA+  T+ AN+S RDNQIQEM GHL RL  EHE +I G ESA  L   ++L +E
Sbjct:    4 VESQLDSERKLVSELQERIVRCNADIFGRDLEVMQLKSALREAQEQFSLEKADLQADISSFAAKQIVLDTRLEELSLRNKGLEDEIKQCETDKMEMERLHAVYEMALQDDISSLKVEVADKNGHVEAVNKDLDIFKLKCDMLMAEKDELNARAQTLMANVSXRDNQIQEMAGHLSRLQTEHEGLIVGSESACNLSFLVELGLE 206          

Query:    1 MVDMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRY 897
            M DME+TE++KSDS G DN+  P+SS+ LVE LEEMDQS KQMLKLIKEDGDSLP   E + Q  PEL++EF+RMYRSLAGCY HL K AHK         GFGDSE GF+ GSPL+TPDAK  L KS  QVV                 KNG                NSPVSNY VP     FDSQGWQQKI  LE E                 +   +NEI +L+ DLEVTKERLKGS+ EI  LKHEL  R+S+ A QMQG            ESQL  ERKHV ELQE+IV +
Sbjct:  114 MXDMEKTELKKSDSAGLDNSITPDSSMXLVEYLEEMDQSXKQMLKLIKEDGDSLPNKDEXFLQKXPELVQEFHRMYRSLAGCYXHLNK-AHK---------GFGDSEYGFNQGSPLLTPDAKHGLRKSDDQVVGFDISLSSDGSSPALSIKNGAESSSSSSLGSESDSPNSPVSNYXVPPPSADFDSQGWQQKIAELERE-----------------APDSDNEIRKLMEDLEVTKERLKGSNKEIANLKHELADRISKGADQMQG-----------FESQLDSERKHVSELQERIVSF 374          

Query:  661 RENEIARLVADLEVTKERLKGSDDEIVKLKHEL-THRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            R+++I  +V +L   K+RL+ S+ E+  L+ +L +++ SEE   +QGQL+  ++DI+M +++L+ E++ V +LQE+I R    +  RD EVM+LK A+ DA+E+   EKA ++A+IS L  ++T L+ ++++   R + LEDEIR+ +  K EME         L+ +I  LK ++ ER+  +E +NK  D  K        E+ EL+ K   + A  SSRD+QI E+  +L+++  EH++++ G E A +LV+EL  R +EL++E+  QRV I +GAE+KREAIRQLCFSLEHYR+GY  LRQA +G+ ++    A
Sbjct:  359 RDSKIEAMVKELRAXKDRLQHSEKEVASLRQQLESNKPSEEIQXLQGQLESAKKDISMWKTKLNTEKREVSKLQERISRLKGSLXDRDNEVMDLKIAVSDAEEKIFPEKAQVKAEISRLQSERTHLEEQLKDWESRGRLLEDEIRQMKAGKAEMEER-------LKGKIEQLKADILERSNQMENLNKTLDAMK-------TERXELSTKAAMLQAEXSSRDDQINEINKNLQQMQTEHQELLNGAEGARKLVEELTERAKELEEEIQRQRVVIMEGAEEKREAIRQLCFSLEHYRNGYXMLRQACMGNNKRVPVLA 661          

Query:  103 EMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPD---AKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRR-------LILNLSKHREN---EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQAD--ISSLTEKQTILDTRIEEGSL----------------------RNKNLEDEIR--RCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVA 1602
            EMD+SIK+MLKLI+EDGDS  K  E Y Q +PELI   EEFYR+YRSLA  YDH+T E  K  PS +  Q    S+ G +  S L +PD    KL  HKS  +                   K G           X    +S V+NY  P L    D QG  +KI  LE EL  VKEKL+M++              H E    +IA    +L    E+L+ S++EI +L  ++  +  E +    G     + + A   + L       L L+ +  +++  +       +E + A H+   + +LE    Q +  +    E     + +I EG+                       R+  +E  ++  R   D+++     VA  +  Q E +    E+    G +E+  KD   +K K +    E  +L  ++  +  +L  RDN++ +++             IA  ++  ++  E K +V+     + S+R  + +  +      R L   +   ++G  E+ +   G   Q  A
Sbjct:   14 EMDRSIKRMLKLIEEDGDSFAKKAEMYYQKRPELIAHVEEFYRLYRSLAERYDHVTGELRKNAPSDLQSQSSCLSDIGSELPSALPSPDVQPGKLGRHKSGPRAAGFDFFLGPGGNSSDHYQKEGDESFSFTDYSEXESD-DSSVNNYSTP-LSNGLD-QGQTRKIIELEIELREVKEKLRMQQEENVDSSFXGAKPDHTEEFPAKIAEYEHELTSRNEKLRESEEEIARLNIKI--KRYESSQHNNGLKLAXEPESAQXNNGLK------LALEPESAQHNNGL----KLALEPEPAQHNNGLKLALEPEPAQHNNGLKLALEFSKPKEAKIHEGARDREINEPSEXHKRVXGSGEVQDRDSKIEAMVKELRAXKDRLQHSEKEVA-SLRQQLESNKPSEEIQXLQGQLESAKKDISMWKTKLNTEKREVSKLQERISRLKGSLXDRDNEVMDLK-------------IAVSDAEEKIFPE-KAQVKAEISRLQSERTHLEEQLKDWESRGRLLEDEIRQMKAGKAEMEERLKGKIEQLKA 525          

Query:  661 RENEIARLVADLEVTKERLKGSDDEIVKLKHEL-THRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            R+++I  +V +L   K+RL+ S+ E+  L+ +L +++ SEE   +QGQL+  ++DI+M +++L+ E++ V +LQE+I R    +  RD EVM+LK A+ DA+E+   EKA ++A+IS L  ++T L+ ++++   R + LEDEIR+ +  K EME         L+ +I  LK ++ ER+  +E +NK  D  K        E+ EL+ K   + A  SSRD+QI E+  +L+++  EH++++ G E A +LV+EL  R +EL++E+  QRV I +GAE+KREAIRQLCFSLEHYR+GY  LRQA +G+ ++    A
Sbjct:  343 RDSKIEAMVKELRAXKDRLQHSEKEVASLRQQLESNKPSEEIQXLQGQLESAKKDISMWKTKLNTEKREVSKLQERISRLKGSLTDRDNEVMDLKIAVSDAEEKIFPEKAQVKAEISRLQSERTHLEEQLKDWESRGRLLEDEIRQMKAGKAEMEER-------LKGKIEQLKADILERSNQMENLNKTLDAMK-------TERXELSTKAAMLQAEXSSRDDQINEINKNLQQMQTEHQELLNGAEGARKLVEELTERAKELEEEIQRQRVVIMEGAEEKREAIRQLCFSLEHYRNGYXMLRQACMGNNKRVPVLA 645          

Query:  106 MDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQM-----RRLILNLSKHRENE--IARLVA---DLEVTKERLKGSDDEIVKLK-----------------------------------------HELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M++S+KQMLKLI+EDG SL K  E   Q +P+LI   +EF  M +SLA CY+++T E    +PS   VQG  +SESG  H  PL+TPD KL  HK++++                   K G+               NS  + Y   SL V+ D     +KI V+ T+LSS++EKL+M     R  +LN  ++R  E  ++R++    +L +TK +L+ S+D++ +LK                                          EL  +++E + ++QGQL+V +E+I ML ++L+ E + VL+LQE+I  Y +D+   D E+     AL DAQE  S+EKA LQ++I  L+EKQ +L+ ++ E  L+ K +ED++R+CE +KM+M+ +H AQE+ALQ EIS LKVE+ +R  HVE +NK FD  K KYD++MAEKD ++AKV+T+ A+++SRDNQI++MEGHL++L+ EHE +IAG +S+ +LVDEL+L+V EL+KEVD QRV +S  AE+KR AIRQLCFSLEHYRSGYKELR+AFLGH+R +V A+
Sbjct:    1 MERSVKQMLKLIEEDGVSLAKKAEMCRQTRPDLISKIKEFNSMQQSLAECYEYVTTELTNSIPSEFDVQGVDNSESGHGHDPPLLTPDQKLGFHKASNRA----PSVSSHGASSDLSLKEGSESFSFSSSDSESESFNSSGNAYY--SLPVNTDRSELHKKIIVMGTDLSSMEEKLRMHEEENRDSMLNGEENRNYEELLSRIIGYEEELRLTKVKLQLSEDDVTRLKIELEKSVFFRDLSGTLQAQLELALKDIQMREDDLQVERKRVLELQKKVAEGSEELQGQLKVAEEEITMLNAKLNTESRRVLDLQERITCYKSDLSDHDHEI----KALKDAQENLSVEKAHLQSEILDLSEKQNMLEVKLREWDLQGKFMEDKLRQCEAEKMQMKNLHDAQEIALQGEISQLKVELIDRGEHVEVLNKKFDSLKSKYDMLMAEKDGMSAKVNTLIADVNSRDNQIRQMEGHLQQLHTEHEKLIAGSQSSRKLVDELRLKVVELEKEVDGQRVELSAVAEEKRAAIRQLCFSLEHYRSGYKELREAFLGHKRHSVMAS 545          

Query:  106 MDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMR----------------------------------RLILNLSKHRENEIARLVADLEV-------------------TKERLKGSDDEIVKLK-HELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            MDQ+  ++LK+I++DG SL K  E     +P+LI   EEF  +YRSLA  YDHL  E +K  PS   +Q  G +       +P++TPD KL LH++ HQV                  K+G+               NS    Y   SL V+ D +G  QKI  L   L  +  KLQ+                                   +L L LS   E E+ARL  +LE                    T  R++ +D E+ +++  EL   L++  +++QG L++ QE+I ML ++L  E    L+LQE+IV+Y  D+   D EV   K AL +A+E F  EKA LQ++ISSL E++T+L+ R+ +  L+ ++LE+++++CET+K +++ ++  Q + LQ EIS LKVE+ ++ GH+E VNK+ D  K KYD+VMAEKD +NAK++T+ A+LSSRDN+I +ME  LRR+  E+ ++IAG ES  R V+EL+LRV EL+KEVD QR  +S GAE+KREAIRQLCFSLEHYRSGYKEL QAF  H+R AV A+
Sbjct:    1 MDQTASRVLKMIEQDGASLAKKAEMCKMTRPDLIAEIEEFCSLYRSLAERYDHLNAELYKSTPSEFQMQDAGSAPD-----TPMLTPDQKLGLHQTGHQV----ESASSGGASSDLSPKDGSDSSSSSDSESDS--FNSSGDAYY--SLPVNSDRKGLHQKIIELRNGLPIMDIKLQLNAEDNGDCMLDAQEKENYEELLGRSIMYEEELRDSKLKLQLS---EEEVARLKGELEKRESDMVLAETLQGQLELAHTDLRMREADLEVERIRVMELQQGLADRTNELQGHLKLAQEEINMLRTKLDSEFWQALDLQERIVQYKNDVSALDDEVKASKLALLNAEENFLAEKAHLQSNISSLLERETMLEARLRDWELKGESLEEKLKQCETEKKDLQLVYDIQRIGLQGEISELKVELGDKGGHLEIVNKNLDSLKFKYDMVMAEKDGMNAKINTLIADLSSRDNEIGQMEERLRRIRIENAELIAGSESLQRTVNELRLRVVELEKEVDKQRGELSAGAEEKREAIRQLCFSLEHYRSGYKELCQAF--HKRHAVMAS 540          

Query:  106 MDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPEL---IEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYL--------------------------------VPSLKVHFDSQGWQQKIT----------------------------VLETELSSVKEKLQMRRLILNLSKHRENEIARLVADLE------------------VTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M+QS+KQMLKLI+E GDS  +  E Y++ +PEL   +EEFYRMY++LA   DHLT E  K  PS++  Q               +TPD KL +H+S+HQ V                 K G               + S ++ YL                                +P +  H   +    KIT                             L+ +L S   +++M+   L L K +  E+ +  A+LE                   TK+RL GS++E  KLKHELT+ +S   HQ++ Q  +      MLE+Q          LQ+ I+++ A +   D EV  L +ALH+AQE FSLE+A LQ+DISSL+++  +L+TR+EE   +              +MEM+ +H AQE  L  EI  LK E++ER   V+A+NK+ D  K+ YD++MAEKDEL+A+V T+ A+++S DNQIQ++E HLR+L  E  ++IAG ESA +LVDEL  RV+EL++EV+ QRV ISD AE+KREAIRQLCFSLEHYRSGY+ELRQAF+GH+R  + A+
Sbjct:    1 MEQSVKQMLKLIEEGGDSFEEKAEMYNRKRPELVAHVEEFYRMYQALAERCDHLTGELFKSNPSMLQAQ---------------VTPDQKLGVHRSSHQSVNMDSPLSSGSASSELSLKEGADSFSSSSSDSESESITSSINRYLGTPSNGDGKGLQTMLPSMKEKLQVTEDKDADCIPKVGTHASYEELLGKITEYSQKLEFSEEEIARLNCELKKNESATGTLQAQLESAWREIEMQEANLELEKRQVLELQKQTAELENRVSESDHKICMLEEELEETKKRLMGSEEENEKLKHELTNEISVVKHQLEDQRALA----VMLETQ----------LQDSIIKHMAFVSDHDREVESLNAALHNAQENFSLERAQLQSDISSLSKQVVLLETRLEEWRAK--------------EMEMKGLHEAQETVLLGEIEQLKAELSERGDIVQALNKNLDALKVTYDMLMAEKDELSARVDTLIADVNSWDNQIQQLEDHLRQLRIERVELIAGTESARKLVDELSWRVKELEREVERQRVVISDRAEEKREAIRQLCFSLEHYRSGYQELRQAFIGHKRLPILAS 539          

Query:    7 DMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPELI---EEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYL-VPSLKVHFDSQGWQQ---------------KITVLETELSSVKEKLQ--------------------------------------MRRLILNLSKHRENEIARLVADLEV------------------TKERLKGSDDEIVKLKHELTHR-LSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +++RTE +KS S   D+  +P++S WL +NLEEMDQS+K+MLKLI+EDGDS  K  E Y Q +PELI   E+FYR+YRSLA  YDH+T E  K + S +  QG G S+ G +  S   +PD +    KS  +                   K                  +S V+NYL VP  +     +   +               KI   E EL + KEK+Q                                      M+   L  +K + +E       LEV                  TKERL+GS+ EI  L  EL  R  SE    MQ QL++  +DIAM +++L  E++ V +LQE++ RY   +  R+ E+ ELK  + DA   F LEK+ L A IS L + Q+ L+ +++E  LR ++LE+EI++ + +K E +     QE   + EI  LK + AE    +  +NK  D   LK+D +M+E+DEL+A+VH + + LSSRD+Q  +M+ +L +L  E  +++AG   A RLV+EL+ + ++L++EV+ Q+  +S+ AE+KREAIRQLCFSLEHYR+ Y  LRQAF  H+R AV
Sbjct:   11 NLKRTESKKSHSWWWDSHISPKNSKWLADNLEEMDQSVKRMLKLIEEDGDSFAKKAEMYYQKRPELISHVEDFYRIYRSLAERYDHVTGELRKNILSDLQSQGSGISDLGSEPASTCPSPDQRERRRKSGRRAAGFDFFLGSGGSSSDLYNKGDESSSLSDSESGSD---DSSVNNYLGVPGKQQMQQEENADRSLRGTGNGNCEDLLGKIAGYEEELRAAKEKIQLSEEEIVRLKTELQKYGPLNFTNNFQAELVELPPRDIKMQESELEFAKKQASEFEEGAVGLEVDCSDPGLKIQSLVEELRITKERLQGSEKEIATLIDELASRGSSESISHMQEQLELTHKDIAMWKAKLDREKREVSKLQERVGRYKTSLSDREHEIRELKEVISDADHNFELEKSLLMAKISKLLDDQSHLEEKLKEWELRCQSLEEEIKQVDAEKRETKARLEEQEKLWKTEIEQLKADTAESGDRINDLNKSLDALNLKHDTLMSERDELSARVHALISELSSRDDQKIQMDKYLHQLRIEQAELVAGAGDARRLVEELRSKAKQLEEEVERQKGLVSEAAEEKREAIRQLCFSLEHYRNDYNRLRQAFTVHKRPAV 614          

Query:    7 DMERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGS--PLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRR------------------------------LILNLS-KHRENEIARLVADL----------EVTKERLKGSDDEI----VKLKHELT-----------------------HRLSEEAHQMQGQLQVVQEDIAMLESQLH------------------------WE------RKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAV 1599
            +M+R +  KS S   D+  +P++S WL ENLEEMD+S+++MLKLI+EDGDS  K  E Y Q +PE   L+EEFYRMYRSLA  YDH+T E  K +PS +  Q  G S+ G +  S  P   P+ +LS  K  ++                   +                  +S V+NY V  L  +       +K+  LE EL  +K++LQM++                               I N S +H E E+ARL  +L           + KE +   D+ +     +L+ E+T                         L++E    + +LQ  +++IA L+ QL                         W+      ++ V +LQE+I R    +  RD E+ +LK A+ DA+++   EKA ++A+IS L E++T LD ++ E   R + LED+IR+ +T+K E E  H +       EI+ LK E  ER+ H+E +NK  +  KL       E+D LNA+V  + A++ SRD+QI +M+ HL++L+ EH ++IAG E A +LV  L+ +  +L+KEV+ Q++AI++GAE+KREAIRQLCFSLEHYR+GY  LR+AF+ H+R  V
Sbjct:   11 NMKRLQSRKSHSWWWDSHVSPKNSKWLAENLEEMDRSVRRMLKLIEEDGDSFAKKAEMYYQKRPELVSLVEEFYRMYRSLAERYDHVTGELRKNIPSDLQSQSSGISDIGSELTSTWPSPVPEQRLSHRKPGNRAAGFDFFLGSGGSSSDLQKEGDESSTLTDSEPESD---DSSVNNYSV--LLGNGGDNALSRKVIELEIELREMKDRLQMQQEDNGDGSYRGARNENFEYLLARIAGYEQELKIANQSIQHSEEEVARLNIELHRYKSLEAVNSLQKEFISSKDENVKTEDSELESEITQASKLKENTDGLEAGTVDSDSKIRALTDELRITKEKLQYAEKEIASLKLQLESNRPSEKVDNLQDQLILAHKDINTWKTRLNAEKREVSKLQERIARLRTSLSDRDHEIRDLKLAVSDAEQKIFPEKAQIKAEISKLLEERTSLDEQLREWESRCRCLEDDIRKLQTEKSETEERHYS-------EINQLKAETVERDCHIENLNKSLNALKL-------ERDALNAQVVLLKADIISRDDQINQMDNHLQQLHMEHVELIAGAEEARKLVYTLRSKANDLEKEVERQKIAITEGAEEKREAIRQLCFSLEHYRNGYHRLRKAFVEHKRLPV 625          

Query:  577 KITVLETELSSVK-EKLQMRRLILNLSKHREN---EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            ++ V E +L   K + L++++   +L  H  +   +IA+LVA LE+ +E+LK SDDEI +L+ EL  R S    ++QGQL+V Q+++A LE+QL  ERK + +L++++  Y  +    +LEV +LK+ + DAQ QFSLEK  L ++I+ L+E+   L +R+EE   R+   E++ R+ E +K+++E +   Q+M LQ EIS LK E+ +R   VEAVNK+FDR + KYD++M EKDE NAK+H + A    RDN I  +E  + ++  +  ++I G  +   LV+ELKL+V+EL+KEV  Q   ISD AE+KREAIRQLCFS+EHYRSGYKEL QAF GH+R AV AA
Sbjct:  141 ELKVKEEDLEYEKGQVLELQKKTADLETHVPDCSLKIAKLVAQLELAEEQLKISDDEIARLEEELNSR-SLGTRELQGQLEVAQDNVAALENQLDSERKQIQDLEDRVTWYKTNETNNELEVQKLKADMVDAQAQFSLEKDQLHSEIAHLSEENKQLGSRLEEYKSRSNIFENKSRQFEAEKLKLEELLATQQMVLQGEISCLKEELDQRRHDVEAVNKEFDRHRQKYDVLMTEKDEANAKIHNLMAETRDRDNHIANLEREIIQVCGQKAELITGSAATLNLVNELKLKVDELEKEVTRQNAVISDRAEEKREAIRQLCFSIEHYRSGYKELLQAFSGHKRHAVTAA 487          

Query:  577 KITVLETELSSVK-EKLQMRRLILNLSKHREN---EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            ++ V E  L   K + L++++   +L  H  +   +IA+LVA LE+ +E+LK SDDEI +LK EL  R S   H++QGQL+V QE +A LESQL  ERK + +L+ ++  Y A+    +  V +LK+ + DAQ QFSLEK  L +DI+ L+E+   L +R+EE   R+  +E++ R+ E +K+++E +   Q+M LQ EIS LK E+ +R   VEAVNK+FDR K K D++M EKDE NAK+H + A    R+N I  +E  +  L  +  ++  G  +  RLV ELKL+ + L+KEV  + V ISD AE+KREAIRQLCFS+EHYRSGYKEL QAF GH+  AV AA
Sbjct:  144 ELKVKEENLEYEKGQVLELQKKTADLETHVPDCSLKIAKLVAQLELAEEQLKISDDEIARLKEELNSR-SSGTHELQGQLEVAQEIVAALESQLVSERKQIHDLEGRVTWYKANETNTEHAVQKLKAKMLDAQAQFSLEKDLLHSDIARLSEENKQLGSRLEEYESRSNIIENKSRQLEAEKLKLEELLATQQMDLQGEISCLKEELDQRRHDVEAVNKEFDRHKQKCDVLMTEKDEANAKIHNLMAETRDRNNYIANLERDIILLRGQEAELSTGSAATLRLVKELKLKADGLEKEVILKNVMISDRAEEKREAIRQLCFSIEHYRSGYKELLQAFAGHKCHAVTAA 490          

Query:  577 KITVLETELSSVK-EKLQMRRLILNLSKHREN---EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQMQGQLQVVQEDIAMLESQLHWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            ++ V E  L   K + L++++   +L  H  +   +IA+LVA LE+ +E+LK SDDEI +LK EL  R S   H++QGQL+V QE +A LESQL  ERK + +L+ ++  Y A+    +  V +LK+ + DAQ QFSLEK  L +DI+ L+E+   L +R+EE   R+  +E++ R+ E +K+++E +   Q+M LQ EIS LK E+ +R   VEAVNK+FDR K K D++M EKDE NAK+H + A    R+N I  +E  +  L  +  ++  G  +  RLV ELKL+ + L+KEV  +   ISD AE+KREAIRQLCFS+EHYRSGYKEL QAF GH+  AV AA
Sbjct:  144 ELKVKEENLEYEKGQVLELQKKTADLETHVPDCSLKIAKLVAQLELAEEQLKISDDEIARLKEELNSR-SSGTHELQGQLEVAQEIVAALESQLVSERKQIHDLEGRVTWYKANETNTEHAVQKLKAKMLDAQAQFSLEKDLLHSDIARLSEENKQLGSRLEEYESRSNIIENKSRQLEAEKLKLEELLATQQMDLQGEISCLKEELDQRRHDVEAVNKEFDRHKQKCDVLMTEKDEANAKIHNLMAETRDRNNYIANLERDIILLRGQEAELSTGSAATLRLVKELKLKADGLEKEVILKNAMISDRAEEKREAIRQLCFSIEHYRSGYKELLQAFAGHKCHAVTAA 490          

Query:   10 MERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLHKSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRR------LILNLSKHREN------EIARLVADLEVTKERLKGSDDEIVKLKHELTHRLSEEAHQM-----------------------------QGQLQVVQEDIAMLESQL-----------------------------------HWERKHVLELQEKIVRYSADIFGRDLEVMELKSALHDAQEQFSLEKADLQADISSLTEKQTILDTRIEEGSLRNKNLEDEIRRCETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M+R E  KS S   D+  +P++S WL ENLEEMD+++K+MLKLI+ED DS  K  E Y + +PE   L+EEFYR YRSLA  YDH+T E  K + S +  QG G S++G +  S L +P+  ++  KS+++                   K+G                +S V+NY   +   +    G  ++I  LE EL  VKEKL  +        + +     EN      +I     +L +  E+L+ S++EI KL+ EL +  S ++  M                             + +L++ +E++   E+Q+                                   + E++   +LQE++ R    +  RD E+ +LK+A+ DA+++   EKA+L+A++S L E+QT L   I E   R ++ E++IR  +++K+EM       E  L++ I  LK E+ +R  +++ +N   D  KL       EKD LN +V ++  +++SRD +I  ++ HL  L+ EH  +I+  E A R V+E+K + + L+++V+ Q+  I + AE+KREAIRQLCFSLEHYR+ Y  L+Q F+GH+R  + AA
Sbjct:   12 MKRLESRKSHSWWWDSHISPKNSKWLFENLEEMDRNVKRMLKLIEEDADSFAKKAEMYYKKRPELVALVEEFYRGYRSLAERYDHVTGELRKNVQSDLQSQGSGFSDTGSEPPSTLPSPN--VTHRKSSNRAAGFDFFLGTGGNASDISQKDGEDESSTMTGSEDESD-DSSVNNY--SAFSRNGTDPGMNRRINELENELREVKEKLWTQEGEHAEVSVSSSGATHENADDVYAKINAYEQELMIVNEKLRLSEEEITKLRTELENYKSLDSRNMDVGVELEVEGSVDGVDKELFESSGGTASLREELRITKENLKASETQVASLNTEVNKSSDRIQQLKDQLDSAKKDVATWKTKFNSEKRESTKLQERLARLKTSLSDRDHEIRDLKTAVSDAEQKIFPEKANLKAEMSKLLEEQTHLKELIREWESRGRSFEEQIRNIQSEKIEM-------EAELKNGIQLLKAEIEQRENNIKDLNVSLDNLKL-------EKDNLNVEVGSLKEDVNSRDGRIGSLDRHLNDLHIEHVQLISSLEEACRQVEEIKTKAKNLEEQVERQKTEILEAAEEKREAIRQLCFSLEHYRNNYHMLKQHFIGHKRVPILAA 604          

Query:   10 MERTEMEKSDSCGQDNTNNPESSIWLVENLEEMDQSIKQMLKLIKEDGDSLPKTVEHYSQGKPE---LIEEFYRMYRSLAGCYDHLTKEAHKIMPSVIPVQGFGDSESGFDHGSPLMTPDAKLSLH-KSAHQVVXXXXXXXXXXXXXXXXXKNGTXXXXXXXXXXXXXXLNSPVSNYLVPSLKVHFDSQGWQQKITVLETELSSVKEKLQMRR-------LILNLSKHRENEIARLVA---DLEVTKERLKGSDDEIVKLKHEL-THRL---------------------SEEAHQM-----------------QGQLQVVQEDIAMLESQLHWERKHVLELQ-------EKI--VRYSADIFGRDLEVMELK--------SALHDAQEQFSLEKADLQADISSLTEKQTILDTRI--EEGSLRNK---------NLEDEIR------RC-ETDKMEMERMHVAQEMALQDEISGLKVEVAERNGHVEAVNKDFDRFKLKYDIVMAEKDELNAKVHTVTANLSSRDNQIQEMEGHLRRLNAEHEDMIAGYESAHRLVDELKLRVEELQKEVDSQRVAISDGAEQKREAIRQLCFSLEHYRSGYKELRQAFLGHRRQAVAAA 1608
            M R E  KS S   D+  +P++S WL ENLEEMD+S+K+MLKLI+ED DS  K  E Y Q +PE   L+EEFYR+YR+LA  YDH+T E  K +PS +  QG G S++G +  S   +P  K     KS+ +                   K+G                +S V+NY       +    G  ++I  LETEL  VKEKL M+           + +++ E+   ++ A   +L    E+L+ S++EI K K EL  +RL                       EAH+M                  G+++ +  ++ + +  L      +  L+       E+I  +    ++  +D+   + K        + LH+   +     +D   +I  L  + +  + +I  E+  L+++         +LE++IR      RC E D   ++   +  E AL+ EI  LK  + +R  +++ +N   D  KL       EKD L+ +V ++   ++SRD +I+ +  HL  L+ EH  +IAG E AH+ V+ELK + ++L++EV+ QR  I +GAE+KREAIRQLCFSLEHYR GY  LRQ  +GHRR  V AA
Sbjct:   12 MRRLESRKSHSWWWDSHISPKNSKWLSENLEEMDRSVKRMLKLIEEDADSFAKKAEMYYQKRPELVALVEEFYRVYRALAERYDHVTGELRKNIPSDLQSQGSGISDAGSEPSSTWPSPTPKRGGRLKSSTRAAGFEYFLGSSGNGTDVYQKDGDESSTLTDSEEESD--DSSVNNY--SGFSRNGSDLGINRRIMELETELREVKEKLWMQEEEHADGSTRGSRNENTEDLYTKINAYEQELMTVNEKLRLSEEEITKQKIELQKYRLFNTENLEAGFESSLTKKHINEGGEAHKMIEVEGSIDGVDKELFDQNGEIETLARELRITKENLKASEMQITSLKFEANKSSERIQQLHDQLELARKDISTWKTKFNSEKRESTKLHERLARLRTSLSDRDHEIRDLKTEVSDAEQKIFPEKAQLKSEMSKVLEERTHLEEQIREWESRGRCFEDDIRRIQSEKMEMEEALKGEIQLLKAGIEQRENNIKELNTSIDTLKL-------EKDNLHVEVGSLKEEVNSRDGRIEHLNSHLNELHVEHVQLIAGMEEAHKHVEELKSKAKQLEEEVERQRTVILEGAEEKREAIRQLCFSLEHYRDGYNMLRQHVMGHRRVPVLAA 621