ppa004300m, ppa004300m (mRNA) Prunus persica

Query:  115 LQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVH---PNSNQQGPNGQI--------PSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            LQ+QCL V ++ F  SLK TID ++   S++SQF   F DFRL+NAISDCL+LLDF+AD+L+WSLSA QN KGK+N TG L SDL+TWLS+   NQDTC  GF GTN IV+ +++  L QV SLV  LLT VH   P     G  G +        PSWV    RKLLQA  VS D  VA DGTGN+T V DAV AAPDYS   YVIYIK+G YRENVEIKKKKWNLMM+GDGM AT+I+GNRS++DGWTT+ SATFAV G+GFIARD+TFENTAGPEKHQAVALRSDSDLSV+YRC++RGYQDTLY HT RQFYR+C+ISGTVDFIFGDATVVFQNCQIL KKGLPNQKN+ITAQGRKDP +PTG SIQF NI+ADSDL  ASVNST +YLGRPWK YSRT+IM+S++S+ IRPEGWLEWNGDFAL++L+YGEYMNYGP AGLGSRV+WPG+ + N S QA N+TV +FI GNLWLPSTGVKY+A   V
Sbjct:   39 LQSQCLAVPSSAFISSLKSTIDVLRGTMSVVSQFTKVFNDFRLSNAISDCLELLDFAADDLSWSLSAIQNPKGKDNGTGDLGSDLKTWLSSTFTNQDTCIEGFVGTNGIVKTVVAESLSQVASLVHSLLTMVHDPAPKGKSNGGGGGVKHVGSGDFPSWVGKHSRKLLQASSVSPDVTVAADGTGNYTTVMDAVQAAPDYSQNHYVIYIKQGIYRENVEIKKKKWNLMMVGDGMGATVITGNRSYIDGWTTYASATFAVKGKGFIARDMTFENTAGPEKHQAVALRSDSDLSVYYRCSMRGYQDTLYPHTNRQFYRECRISGTVDFIFGDATVVFQNCQILVKKGLPNQKNTITAQGRKDPAQPTGFSIQFSNISADSDL-LASVNSTLSYLGRPWKQYSRTIIMKSYISDAIRPEGWLEWNGDFALDTLYYGEYMNYGPSAGLGSRVQWPGFHLLNNSAQAANFTVTEFIAGNLWLPSTGVKYSAGLAV 527          

Query:  109 DDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLT---QVHP-------NSNQQGPNGQIPSWVKTKDRKLLQA--DGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            ++L++   +  ++    +LK T++  +    ++++F      +R   AI DC +LLDFS  EL WSL   ++ +  + +  +   +L+ WLSAAL NQDTC  GFEGT+  ++  I   L QVT L+  +L    Q+H        NS ++ P+   P W+   D+ LL A  + + VD IV+ DG+G++ ++  A+  AP YS RRY+IY+K+G Y+EN+++KKKK  +M++GDG+ AT+++GNR+F+ GWTTFR+AT AVSG+GFIARDITF NTAGP+  Q VALR DSD S FYRC++ GYQDTLY H++RQFYR+C I GT+DFIFG+   V QNC+I  +K LP QK +ITAQGRK P++ TG SIQ   + A          + PTYLGRPWK YSRTV + +++S++++P GWLEWNG+FAL +L+YGEY NYGPGA L  RV+WPGY    +++ A  +TV +FI+G  WLPSTGV+++A
Sbjct:   90 NELESMGPRSPSSILTAALKTTLNEARIAVQMVTRFNALSSSYREQIAIEDCKELLDFSVSELAWSLLEMKSIRAGSTNV-QSEGNLKAWLSAALSNQDTCLEGFEGTDRRIESFIRGSLKQVTQLISNVLAMYVQLHSLPFKPPRNSTEKSPSQDFPKWMTDGDKDLLLAHPNQMGVDTIVSLDGSGHYRSIAQAIYEAPSYSNRRYIIYVKKGVYKENIDMKKKKTKIMIVGDGIGATVVTGNRNFMQGWTTFRTATVAVSGKGFIARDITFRNTAGPKNFQGVALRVDSDQSAFYRCSMEGYQDTLYAHSLRQFYRECDIHGTIDFIFGNGAAVLQNCKIFTRKPLPLQKVTITAQGRKSPDQSTGFSIQDSYVYA----------TQPTYLGRPWKQYSRTVFLNTYMSSLVQPRGWLEWNGNFALGTLYYGEYRNYGPGALLSGRVQWPGYHKIQDTSVANFFTVGRFIDGLSWLPSTGVRFSA 567          

Query:  232 DFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTN---SIVQGL-----ISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGV---SVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            D  LA A+ DC +LLD + D LN SLS+S +             DL+TWLSAA   Q+TC NGFE  N   S+++ L      S+    + + + +L   +        P  ++P W+  KDRKLLQ+        DA+VA DG+G +  +++A+ A PD S + +VIY+K+G Y ENV ++K KWN++MIGDGM+ T++SG  +FVDG  TF +ATFAV G+GF+AR++ F NTAG  KHQAVAL S +D +VFYRC I  +QD+LY H+ RQFYR+C I GTVDFIFG++ VVFQNC IL K+ +P Q+N+ITAQG+ DPN+ TGI+IQ C I     L +A ++S  TYLGRPWK YS TV M S + ++I P GWL W G  A N++FY E+ N+GPG+   +RVKW G +   +  +A  +TV  FI+G+ W+   GV +
Sbjct:  129 DKMLAGALDDCYELLDLAIDNLNSSLSSSLDN----------FDDLKTWLSAAGTYQETCINGFESGNLRSSVLEFLKNSTEFSSNSLAIITEISKLAGSISSRRLMGLPEDKVPKWLSAKDRKLLQSSSTLKKKADAVVATDGSGKYKTISEALKAVPDKSKKSFVIYVKKGVYNENVRVEKSKWNVLMIGDGMNKTVVSGKLNFVDGTPTFSTATFAVFGKGFVAREMGFRNTAGAIKHQAVALMSSADQTVFYRCLIDAFQDSLYAHSHRQFYRECDIYGTVDFIFGNSAVVFQNCNILPKQPMPGQQNTITAQGKNDPNQNTGIAIQNCTI-----LPSADLSSVKTYLGRPWKNYSTTVYMHSMMGSLIDPAGWLPWTGTTAPNTIFYSEFQNFGPGSSTKNRVKWKGLRNITQK-EASKFTVKSFIDGSKWISDAGVSF 557          

Query:  250 AISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFE--GTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDA--IVAQDGTGNFTNVTDAVLAAPDYS-MRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            A +DC++L D +  +LN +L  +         T     D +TWLS AL N  TC +GF   G +     LIS     V+ L+   L+       +    G  P+WVK  DRKLLQ+  ++  A  +V++DG+G++T +  A+ AA   S   RYVIY+K GTY ENV+I     N+ ++GDG+  TI++G+RS   G TT+ SAT AV G GFIAR +T  NTAG   HQAVALRS SDLSV+Y+C+  GYQDTLY ++ RQFYR+C I GTVDFIFG+A VVFQ C I A+   PN+ N++TAQGR DPN+ TGISI  C +TA SDL+A   +S  TYLGRPWK YSRTV ++++L ++I   GWLEW+GDFALN+L+YGEYMN GPG+    RV W GY V   ST+A  +TV  FI GN WLPST V +T+
Sbjct:   22 AWNDCVELYDHTILKLNKTLDPN---------TRCTQVDAQTWLSTALTNLQTCQDGFIELGVSDHFLPLIS---NNVSKLISNTLSINKVPYAEPSYKGGYPTWVKPGDRKLLQSSSLASQANIVVSKDGSGDYTTIGAAITAASKRSGSGRYVIYVKAGTYSENVQIGSGLKNITLLGDGIGKTIVTGSRSVGGGSTTYNSATVAVVGDGFIARGMTIRNTAGASNHQAVALRSGSDLSVYYQCSFEGYQDTLYVYSDRQFYRECDIYGTVDFIFGNAAVVFQKCNIYARNP-PNKVNTVTAQGRTDPNQNTGISIHDCEVTAASDLKAVQ-SSVKTYLGRPWKEYSRTVFLKTYLDSLINSAGWLEWSGDFALNTLYYGEYMNTGPGSSTSGRVNWTGYHVITSSTEAAKFTVGNFISGNSWLPSTNVPFTS 442          

Query:  550 PSWVKTKDRKLLQ--ADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYREN-VEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            P W+  ++R LLQ     +  D IV+QDG G +  +T+A+  AP+YS RR +IY+K G Y EN +++ +KK NLM IGDG   TII+G +S  +  TTF +A+FA +G GFIARD+TFEN AGP KHQAVALR  +D  V YRCNI GYQDTLY H+ RQF+R+C I GTVDFIFG+A VVFQNC + A+K +  QKN+ITAQ RKDPN+ TGISI  C I    DL A    S PTYLGRPWKLYSRTV M S++ + I P+GWLEWN  FAL++L+YGEYMNYGPG  +G RV WPGY+V     +A  +TV QFI G+ WLPSTGV + A
Sbjct:   16 PKWLTRRERSLLQMPVPAIQADIIVSQDGNGTYKTITEAIKKAPEYSSRRTIIYVKAGRYEENNLKVGRKKTNLMFIGDGKGKTIITGGKSVFNNLTTFHTASFAATGAGFIARDMTFENWAGPGKHQAVALRVGADHGVVYRCNIIGYQDTLYVHSQRQFFRECDIYGTVDFIFGNAAVVFQNCSLYARKPMAQQKNTITAQNRKDPNQNTGISIHACRILPAGDL-APVKGSFPTYLGRPWKLYSRTVYMLSYMGDHIHPKGWLEWNTTFALDTLYYGEYMNYGPGGAVGQRVNWPGYRVITSVVEATKFTVGQFIYGSSWLPSTGVAFLA 347          

Query:  244 ANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGF-EGTNSIVQGLIS--AGLGQVTS----LVQELLTQVHPNSNQQG---------------PNGQIPSWVK----------TKDRKLLQ--ADG---VSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRR---YVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            A A+ DC  L + + D L    + S   K     T +L   +RT LS  + NQ TC +G  +  NS+V  L++  +   Q+ S    LV   L+Q      ++G               P  +I   +K          ++  ++L    DG   VS    V+ +GT NFT + DA+  AP+ S      +VIY+K G Y E   + K K  +M++GDG++ T+I+GNRS VDGWTTF SATFAVSG  F+A DITF NTAGPEKHQAVA+R+++DLS FYRC+  GYQDTLY H++RQFYRDC + GTVDFIFG++  +FQNC + A+K +PNQKN+ TAQGR DPN+ TGISI  C I A  DL A  +NST  YLGRPWK YSRTV MQS++ ++I P GWLEWNG   L++L+YGE+ NYGPGA    RV+WPGY + N S QA N+TV  F  G+ WL +  + +
Sbjct:   98 AGALDDCRQLSELNVDYLQ---TISGELKSAELMTDELVERVRTLLSGIVTNQQTCYDGLVDSRNSMVAALLAPLSNANQLYSVSLGLVSRALSQTRKRRKRRGLTENRFLKELDRVREPTSKIIEVLKKGSLNTSRGSSRGGRILAELVDGGVLVSNTVTVSPNGTDNFTTIADAISFAPNSSNIEDGYFVIYVKEGYYEEYPMVPKYKKGIMLLGDGINRTVITGNRSVVDGWTTFNSATFAVSGERFVAIDITFRNTAGPEKHQAVAVRNNADLSTFYRCSFEGYQDTLYAHSLRQFYRDCIVYGTVDFIFGNSACIFQNCNLYARKPMPNQKNAFTAQGRMDPNQNTGISIHNCTIEAAPDL-AMDLNSTLNYLGRPWKQYSRTVYMQSYIGSLIDPVGWLEWNGTVGLDTLYYGEFENYGPGANTSMRVQWPGYTLMNAS-QAVNFTVYNFTMGDTWLTNLDIPF 562          

Query:  550 PSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            P W+   DR+LLQA  V+ D  VA DG+GN+  V +AV +AP+ S +RY+I IK G Y+ENVE+ KKK N+M +GDG   TII+ +R+ VDG TTF SAT AV G GF+ARDITF+NTAGP KHQAVALR  SDLS FYRC++  YQDTLY H++RQF+  C ++GTVDFIFG+A  V Q+C I A++    Q+N +TAQGR DPN+ TGI IQ C I A SDL+    +S PTYLGRPWK YSRTV+MQ+ +S+VI P GW  WNG+FAL++LFY EY N G GA    RV W G++V   +++A+ +T   FI G+ WLPSTG  ++
Sbjct:   36 PEWLSAGDRRLLQASTVTADVTVAADGSGNYKTVGEAVASAPERSSKRYIIRIKAGVYKENVEVPKKKTNIMFVGDGRTNTIITASRNVVDGSTTFHSATVAVVGDGFLARDITFQNTAGPSKHQAVALRVGSDLSAFYRCDVLAYQDTLYVHSLRQFFVGCLVAGTVDFIFGNAAAVLQDCDIHARRPNSGQRNMVTAQGRDDPNQNTGIVIQKCRIGATSDLKPVQ-SSFPTYLGRPWKEYSRTVVMQTSISDVINPAGWYPWNGNFALDTLFYAEYQNTGAGADTSKRVNWKGFKVITSASEAQAFTAGSFIGGSSWLPSTGFPFS 363          

Query:  160 SLKDTIDAVQQVASILSQFANAFGDFRLA--NAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSD-LRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQA--DGVSVDAIVA--QDGTGNFTNVTDAVLAAP---DYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            SLK +I   ++  S++ ++ +A  +   A   A+ DC  L   + D L   LS+SQ     +     L +D ++T LSA L NQ TC +G + T+S      S   G  T L    L +   N                  RKLL    D VS+  IV   QDG+GNF  + DA+  AP   D S   +VIYI+ G Y E V I K K  LMMIGDG++ T+I+GNRS VDGWTTF SATFAV  +GF+A +ITF NTAG  KHQAVALRS +DLS FY C+   YQDTLYTH++RQFYR+C I GTVDFIFG+A VVFQNC +  +  L  Q N+ITAQGR DPN+ TG SI  C I A  DL AAS  +T TYLGRPWK YSRTV MQS + ++I P GW  W+GDFAL++L+Y EY N GPG+   +RV W GY V   S  A N+TV  F+ G  WLP TGV YT
Sbjct:  121 SLKKSIATSRKFLSLVDKYLSARSNLSAAAVRALQDCRFLGGLNLDYL---LSSSQVADANSKILSVLEADDVQTLLSALLTNQQTCLDGLQETSSSW----SVKNGVSTPLQNRKLYESLSN------------------RKLLDTGNDQVSISDIVTVNQDGSGNFATINDAIAVAPNNTDGSNGYFVIYIQAGVYEEYVSIAKNKKYLMMIGDGINQTVITGNRSVVDGWTTFNSATFAVVAQGFVAVNITFRNTAGAAKHQAVALRSGADLSTFYLCSFEAYQDTLYTHSLRQFYRECDIYGTVDFIFGNAAVVFQNCNLYPRLPLSGQFNAITAQGRTDPNQNTGTSIHNCVIRAADDL-AASNGTTKTYLGRPWKEYSRTVYMQSNMGSLINPSGWSIWSGDFALSTLYYAEYNNTGPGSNTSNRVTWSGYHVIGPS-DAANFTVGNFLLGGDWLPQTGVPYT 562          

Query:  163 LKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTN--SIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDA--IVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            LK+++  +Q V  +         D R   A+SDC++L+D S   +  S+ A          T    +D   WLS  L N  TC++G  G +  S+ +GL        TSL   +          Q  + + P WV ++DRK+L++    + A  +VA+DG+GN+  V +A+ + P+ S  RYVI++K+GTY+ENVEI  K+ N+M++GDGMD+T+I+G+ + +DG TTF+SAT A  G GFIA+DI F+NTAGP+KHQAVALR  +D +V  RC I  YQDTLY HT RQFYRDC I+GTVDFIFG+A VVFQNC+++A+K +  Q N +TAQGR +P + TG SIQ CNI A SDLE     +  +YLGRPWK YSR V++QS++ + I P GW                            RVKWPGY+V     +A+N+TVA+ I+G  WL STGV YT
Sbjct:   71 LKESMSHLQGVMEMTVDVNRRMNDPRDQAALSDCVELMDLSMGRIRDSVEAL------GRGTVDSHADAHAWLSGVLTNYITCTDGINGPSRISMERGLKHLISRAETSLAMLVAVSPAKEDVLQPLHSEFPPWVDSRDRKILESSSKDIKANVVVAKDGSGNYKTVKEAIASVPNNSKTRYVIHVKKGTYKENVEIVTKQKNVMIVGDGMDSTVITGSLNVIDGSTTFKSATLAAVGDGFIAQDIWFQNTAGPQKHQAVALRVGADQAVINRCRIDAYQDTLYAHTNRQFYRDCYITGTVDFIFGNAAVVFQNCKLVARKPMDKQANMVTAQGRTNPYQNTGTSIQNCNIIASSDLEPVK-GTIKSYLGRPWKEYSRAVVLQSYIGDHIDPAGWSV-------------------------KRVKWPGYRVITSPAEARNFTVAELIQGGTWLESTGVAYT 500          

Query:  112 DLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFG-----------DFRLANAISDCLDLLDFSADELNWSLSASQNQKGK--NNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIV-----------QGLISAGL---GQVTSLVQEL--------LTQVHPNSNQQGPNGQIPSWVKTKDRKLLQAD--GVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            D +  C+  S T  AG+  D  D VQ   +   +  +A             D R + A+ +C DL++++ D+L  S     NQ G    +    + +D++ WLSA +  Q+TC +GFE T                 L S GL   G+V+S++  L        L    P       + + P W  ++ RKLLQA+   +  +  VA+DG+G+F  + +A+   P +S + +++YIK+G Y E V+I K   NLMM+GDG   T I+G+ +FVDG  TF++AT AV G GFIA+ I FEN+AG  KHQAVALR  SD S+FY C + GYQDTLYTHT RQFYRDC ISGT+DFIFGDA V+FQNC  + +K L NQ+  +TAQGRK+  +P+ I IQ    TAD +      N   +YLGRPWK +SRT+IM+S++ ++I+P GWL W GDFAL + FY E+ N GPGA    RVKW G +    S  A ++   +F+ G+ W+PSTGV Y +
Sbjct:   67 DYKDACVN-SLTSKAGNTTDPKDLVQAAFASAMEHLSAAAKNSTLLQELNKDPRASQALQNCEDLVNYAIDDLKKSF----NQVGDFDYSKMDNIIADIKIWLSAVITYQETCLDGFENTTGDAGEKMRQILKTSMELSSNGLAIVGEVSSILSNLQLANLNRRLLSDDPADPDNHIDDEFPYWSHSEGRKLLQANVSELKPNLTVAKDGSGDFKTINEAIRQLPKFSNQTFILYIKKGIYEEQVQINKTFTNLMMVGDGPTKTKITGSLNFVDGTPTFKTATVAVLGDGFIAKGIGFENSAGAAKHQAVALRVQSDRSIFYNCQMDGYQDTLYTHTKRQFYRDCTISGTIDFIFGDAAVIFQNCTFVVRKPLDNQQCIVTAQGRKERRQPSAIIIQNSTFTADPEYYPYR-NELKSYLGRPWKEFSRTIIMESYIEDLIQPSGWLPWAGDFALRTCFYTEFRNRGPGAKTHDRVKWRGIKTIKPS-HAIDFAPGRFLSGDRWIPSTGVPYNS 572          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFG 1548
            T+D++++CLKV A+EFAGSL+DTI AVQQVASILSQFA AFGDF L+NAISDCLDLLDF+ADELNWSLSASQN +GK+NSTGKLSSDLRTWLSAALVNQDTCS+GFEGTNSIV+GL++ GL QVTSLVQ LLTQV PN++  GPNG+IPSWVK +DRKLLQA GV+VDA+VAQDGTGNFTNVTDAVLAAPD SM RYVIYIK GTY+ENVEIKKKKWNLMMIGDGMDATIISG+R+FVDGWTTFRSATFAVSGRGFIARD+TFENTAGPEKHQAVALRSDSDLSVFYRC IRGYQDTLY H MRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNS+TAQGRKDPNEPTGISIQFCNITAD+DL    VNST TYLGRPWKLYSRTVIMQSFLSN IRPEGWLEWN DFAL++L YGEY+NYGPGAGL SRVKWPGY+VFNESTQ +NYTVAQFIEG+LWLP+TGVKYTA  G
Sbjct:   29 TNDIRSECLKVPASEFAGSLRDTIGAVQQVASILSQFATAFGDFHLSNAISDCLDLLDFTADELNWSLSASQNPEGKDNSTGKLSSDLRTWLSAALVNQDTCSDGFEGTNSIVKGLVTTGLNQVTSLVQGLLTQVQPNTDHHGPNGEIPSWVKAEDRKLLQAGGVNVDAVVAQDGTGNFTNVTDAVLAAPDESMTRYVIYIKGGTYKENVEIKKKKWNLMMIGDGMDATIISGSRNFVDGWTTFRSATFAVSGRGFIARDLTFENTAGPEKHQAVALRSDSDLSVFYRCQIRGYQDTLYAHAMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSVTAQGRKDPNEPTGISIQFCNITADADL-LPFVNSTSTYLGRPWKLYSRTVIMQSFLSNAIRPEGWLEWNADFALSTLSYGEYINYGPGAGLESRVKWPGYRVFNESTQVQNYTVAQFIEGDLWLPTTGVKYTAGLG 508          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQ-QGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVN-STPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            ++ +Q++CLKV  +EF GS+ +TI+ +QQV SILS  A  FGDFRL+NA+ DCL+L+D S D+L+W+LSA+QN+ GK+NSTG LSSDLRTWLSA LVNQDTC+ G +GTNSIV+ L+S  L Q+TSLV ELL QVHP S+Q +  NGQ P+W K +DRKLLQA+GV VD +VAQDGTGNFTN+T A+L+APDYS++RYVIY+K+G Y+E VEIKKKKWN+MMIGDGMDAT+ISGN +FVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKH AVALRSDSDLS FYRC  RGYQDTLYTH+MRQFYRDCKISGTVDFIFGD TV+FQNCQILA+K LPNQKNSITA GRK  +EPTG S QFCNI+A  DL A  VN STPTYLGRPWK YSRT+IMQSF+SN+I+P GWLEWNGD  L +LFYGE+MNYGPGAGLGSRV WPGYQ FN+S QAKNYTVA+FIEGNLWLPSTGVKYT+ FGV
Sbjct:   31 SNTIQSECLKVPNSEFGGSIINTINVLQQVVSILSDVAKGFGDFRLSNAVDDCLELMDDSTDQLSWTLSATQNKNGKHNSTGNLSSDLRTWLSATLVNQDTCNEGLDGTNSIVKSLVSGSLNQITSLVLELLGQVHPTSDQHESSNGQTPAWFKAEDRKLLQANGVPVDVVVAQDGTGNFTNITAAILSAPDYSLKRYVIYVKKGLYKEYVEIKKKKWNIMMIGDGMDATVISGNHNFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHMAVALRSDSDLSAFYRCEFRGYQDTLYTHSMRQFYRDCKISGTVDFIFGDGTVMFQNCQILARKALPNQKNSITAHGRKYKDEPTGFSFQFCNISAHPDLLATPVNSSTPTYLGRPWKEYSRTIIMQSFMSNMIKPAGWLEWNGDMFLKTLFYGEHMNYGPGAGLGSRVTWPGYQKFNQSGQAKNYTVAEFIEGNLWLPSTGVKYTSGFGV 514          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQ---QGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDL--EAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            T+ + ++ LKV+ +EF G+++  +D +Q+V SILS+F + FGD RL+NA+SDCLDLLD S+DEL+WS+SA+Q+ KGK+NSTG  SSDLRTWLSAAL NQDTC +GF+GTN +V+GL+S G+GQV SL+Q+LLTQV P S+      P GQ PSWVKT +RKLLQA+ VS DA+VA DGTGN+T V DAVLAAP+YSM+RYVI+IKRG Y ENVEIKKKKWNLMM+GDGMDATIISGNRSF+DGWTTFRSATFAVSGRGFIARDITF+NTAGPEKHQAVALRSDSDLSVF+RC I GYQD+LYTHTMRQFYR+CKISGTVDFIFGDAT +FQNC I AKKGLPNQKN+ITA GRK+P+EPTG SIQFCNI+AD DL     S NST TYLGRPWK YSRT+ MQS++S+V+RPEGWLEWNGDFAL++L+Y EYMNYGPGAG+ +RVKW GY V N+S+QA N+TV+QFIEGNLWLPSTGV +TA  GV
Sbjct:   41 TNTVGSELLKVAPSEFEGTVRTVVDVLQEVTSILSEFGSGFGDSRLSNAVSDCLDLLDMSSDELDWSVSATQSPKGKHNSTGNTSSDLRTWLSAALANQDTCIDGFDGTNGMVKGLVSTGIGQVMSLLQQLLTQVKPVSDHFSFSSPQGQYPSWVKTGERKLLQANVVSFDAVVAADGTGNYTKVMDAVLAAPNYSMQRYVIHIKRGVYYENVEIKKKKWNLMMVGDGMDATIISGNRSFIDGWTTFRSATFAVSGRGFIARDITFQNTAGPEKHQAVALRSDSDLSVFFRCGIFGYQDSLYTHTMRQFYRECKISGTVDFIFGDATAIFQNCHISAKKGLPNQKNTITAHGRKNPDEPTGFSIQFCNISADYDLVNSVNSFNSTHTYLGRPWKPYSRTIFMQSYISDVLRPEGWLEWNGDFALDTLYYAEYMNYGPGAGVANRVKWQGYHVMNDSSQASNFTVSQFIEGNLWLPSTGVTFTAGLGV 527          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQ---QGPNGQIPSWVKTKDRKLLQA-DGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAA----SVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFG 1548
            T+ + ++ LKV+ +EFAG+++  +D +Q + SILS+F + FGD RL+NA+SDCL+LLD S+DEL+WS+SA+Q+ KGK+NSTG  SSDLRTWLSAAL NQDTC +GF+GTN IV+GL+S GLGQV SL+Q+LLTQV+P S+      P G  P WVK  +RKLLQA +GVS DA+VA DGTGNFT V DAVLAAP+YSM+RYVI+IKRG Y ENVEIKKKKWNLMM+GDGMD T+ISGNRSF+DGWTTFRSATFAVSGRGF+ARDITF+NTAGPEKHQAVALRSDSDLSVF+RC I GYQD+LYTHTMRQFYR+CKISGTVDFIFGDAT +FQNC I AKKGLPNQKN+ITA GRK+P+EPTG SIQFCNI+AD DL  +    S NS  TYLGRPWK YSRTV MQS++S+V+RPEGWLEWNGDFAL++L+Y EYMNYGPGAG+ +RVKWPGY V N+S+QA N+TV+QFIEGNLWLPSTGV +TA  G
Sbjct:   38 TNTVGSELLKVAPSEFAGTVRTVVDVLQDITSILSEFGSGFGDSRLSNAVSDCLELLDMSSDELDWSVSATQSPKGKHNSTGNTSSDLRTWLSAALANQDTCMDGFDGTNGIVKGLVSTGLGQVMSLLQQLLTQVNPVSDHYTFSSPQGHFPPWVKPGERKLLQAANGVSFDAVVAADGTGNFTKVMDAVLAAPNYSMQRYVIHIKRGVYNENVEIKKKKWNLMMVGDGMDNTVISGNRSFIDGWTTFRSATFAVSGRGFVARDITFQNTAGPEKHQAVALRSDSDLSVFFRCGIFGYQDSLYTHTMRQFYRECKISGTVDFIFGDATAIFQNCHISAKKGLPNQKNTITAHGRKNPDEPTGFSIQFCNISADYDLVNSINNNSNNSIGTYLGRPWKPYSRTVFMQSYISDVLRPEGWLEWNGDFALDTLYYAEYMNYGPGAGVANRVKWPGYHVMNDSSQASNFTVSQFIEGNLWLPSTGVTFTAGLG 526          

Query:  115 LQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHP----------NSNQQGPNG-------QIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            L+T+CLKV ATEF GSLK TIDA+++  S++SQF   F DFRL+NAISDCLDLLD SADEL+W++SASQN   K+NSTG LSSDLRTWLSAA+VNQ TC +GFEGTNS+V+ ++S  L Q+TSLV+ LL  VHP          N +Q+G  G       + P W K +DR+LLQ +GV+ + +VA DG+GNFT + DAV  APD SM RYVIYIK+G Y+ENVEIKKKKWNL+MIGDGMD T+ISGNRSF+DGWTT RSATFAVSGRGFIARDITFENTAGP+KHQAVALRSDSDLSVF+RC I+GYQD+LYTHTMRQFYR+CKI+GTVDFIFGD  V+FQNCQILAK+GLP+QKN+ITAQGRKDPN+PTG SIQFCNI+AD+DL   SVNSTPTYLGRPWKLYSRT+IMQS++S+ IRP+GWLEWN DFAL++L+Y EYMN GPGA L  RVKWPGY V N S QA N+TVAQFIEG+LWLPSTGVKYT+ FGV
Sbjct:   31 LETECLKVPATEFIGSLKTTIDAIRKATSVVSQFGGFFHDFRLSNAISDCLDLLDSSADELSWTMSASQNPNAKDNSTGDLSSDLRTWLSAAMVNQQTCIDGFEGTNSMVKTVVSGSLNQITSLVRNLLIMVHPGPNSKSNGTRNGSQKGGGGGGHPGQSRFPVWFKREDRRLLQINGVTANVVVAADGSGNFTRIMDAVETAPDKSMNRYVIYIKKGLYKENVEIKKKKWNLVMIGDGMDVTVISGNRSFIDGWTTLRSATFAVSGRGFIARDITFENTAGPQKHQAVALRSDSDLSVFFRCAIKGYQDSLYTHTMRQFYRECKITGTVDFIFGDGAVLFQNCQILAKQGLPSQKNTITAQGRKDPNQPTGFSIQFCNISADTDL-LPSVNSTPTYLGRPWKLYSRTIIMQSYISDAIRPQGWLEWNQDFALDTLYYAEYMNNGPGASLSERVKWPGYHVLNNSAQAVNFTVAQFIEGDLWLPSTGVKYTSGFGV 525          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQ-----------GPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            TDDLQ  CLKV   +F GSL  T+D ++ V SI+S F N FGD RL NAI+DCLDLLDFSADEL+WS+SASQN  GK+NSTG LSSDLRTWLSAALVNQDTC  GF+GTN+I++GL+S  L Q+TS VQELL  V P++N +           G N + PSWVK +DRKLL  +GV+ + IVA DGTGNFT + DAV AAPDYSM R++IYIK+G Y E V+IKKKKWNLMM+G+GM+ATII+GNR+F+DGWTTFRSATFAVSGRGFIARDITFENTAGP KHQAVALRSDSDLSVF+RC I+ YQD+LYTHTMRQFYR+C++SGTVDFIFGDAT VFQNCQILA+KGLP+QKN++TA GRKDPN+PTG S QFCNI+AD DL    VNS+ TYLGRPWK +SRT+IMQS++SN IRPEGWLEWNG+  L++L+YGEY+NYGPGAG+G RV+WPG+ + N+STQA NYTVAQFI+GNLWLPSTGV+YTA
Sbjct:   29 TDDLQNNCLKVPVNQFVGSLTSTLDIIRDVISIISNFGNVFGDIRLTNAITDCLDLLDFSADELSWSMSASQNPNGKHNSTGDLSSDLRTWLSAALVNQDTCIEGFDGTNNILKGLVSGSLNQITSSVQELLKNVDPHTNSKSSGGGFSGSKSGNNDRFPSWVKHEDRKLLVLNGVTPNVIVAADGTGNFTKIMDAVAAAPDYSMHRHIIYIKKGVYNEYVDIKKKKWNLMMVGEGMNATIITGNRNFIDGWTTFRSATFAVSGRGFIARDITFENTAGPSKHQAVALRSDSDLSVFFRCEIKSYQDSLYTHTMRQFYRECRVSGTVDFIFGDATAVFQNCQILARKGLPDQKNTVTAHGRKDPNQPTGYSFQFCNISADIDL-LPYVNSSYTYLGRPWKNFSRTIIMQSYMSNAIRPEGWLEWNGNVYLDTLYYGEYINYGPGAGVGRRVRWPGFHMLNDSTQANNYTVAQFIQGNLWLPSTGVRYTA 516          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQ-----------GPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            TDDLQ  CLKV   +F GSL  T+D ++ V SI+S F N FGD RL NAI+DCLDLLDFSADEL+WS+SASQN  GK+NSTG LSSDLRTWLSAALVNQDTC  GF+GTN+I++GL+S  L Q+TS VQELL  V P++N +           G N + PSWVK +DRKLL  +GV+ + IVA DGTGNFT + DAV AAPDYSM R++IYIK+G Y E V+IKKKKWNLMM+G+GM+ATII+GNR+F+DGWTTFRSATFAVSGRGFIARDITFENTAGP KHQAVALRSDSDLSVF+RC I+ YQD+LYTHTMRQFYR+C++SGTVDFIFGDAT VFQNCQILA+KGLP+QKN++TA GRKDPN+PTG S QFCNI+AD DL    VNS+ TYLGRPWK +SRT+IMQS++SN IRPEGWLEWNG+  L++L+YGEY+NYGPGAG+G RV+WPG+ + N+STQA NYTVAQFI+GNLWLPSTGV+YTA
Sbjct:   37 TDDLQNNCLKVPVNQFVGSLTSTLDIIRDVISIISNFGNVFGDIRLTNAITDCLDLLDFSADELSWSMSASQNPNGKHNSTGDLSSDLRTWLSAALVNQDTCIEGFDGTNNILKGLVSGSLNQITSSVQELLKNVDPHTNSKSSGGGFSGSKSGNNDRFPSWVKHEDRKLLVLNGVTPNVIVAADGTGNFTKIMDAVAAAPDYSMHRHIIYIKKGVYNEYVDIKKKKWNLMMVGEGMNATIITGNRNFIDGWTTFRSATFAVSGRGFIARDITFENTAGPSKHQAVALRSDSDLSVFFRCEIKSYQDSLYTHTMRQFYRECRVSGTVDFIFGDATAVFQNCQILARKGLPDQKNTVTAHGRKDPNQPTGYSFQFCNISADIDL-LPYVNSSYTYLGRPWKNFSRTIIMQSYMSNAIRPEGWLEWNGNVYLDTLYYGEYINYGPGAGVGRRVRWPGFHMLNDSTQANNYTVAQFIQGNLWLPSTGVRYTA 524          

Query:  130 LKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNG--------QIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFG 1548
            + V   EFAGSL+ TIDA+++V  I+SQF + FGDFRL+NAISDCLDLLDFSAD+L+WSLSASQN  GK+NSTG ++SDLRTWLSAA+ NQ+TC  GFEGTN I + +++ GL QVTSLV +LLT V P  +    NG        + PSW + +D+KLLQA+GV+ DA+VA DGTG FTN+ DAV AAPDYSM R+VIYIK+G Y+ENVEIKKKKWNLMM+GDG++ TIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGP+KHQAVALRSDSDLSVF+RC I+GYQD+LYTHTMRQF+R+C+I+GTVDFIFGDA+VVFQNCQILAK+GLPNQKN+ITAQGRKDPN+PTG SIQFCNI+AD+DL    VNSTPTYLGRPWKLYSRT+IMQS++ N +RP+GWLEWN DFAL++L+Y E+MN+GPGAGLG RV+WPGY   N S QA N+TVA+ IEG+LWLPSTGVKYTA  G
Sbjct:   34 VNVPPAEFAGSLRTTIDAIRKVIPIVSQFGSFFGDFRLSNAISDCLDLLDFSADQLSWSLSASQNPNGKHNSTGDVASDLRTWLSAAMANQETCIEGFEGTNGIAKTVVAGGLNQVTSLVSDLLTMVQPPGSDSRSNGDRKVAEKNRFPSWFEREDQKLLQANGVTADAVVALDGTGTFTNIMDAVAAAPDYSMNRHVIYIKKGLYKENVEIKKKKWNLMMVGDGINGTIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPQKHQAVALRSDSDLSVFFRCAIKGYQDSLYTHTMRQFFRECRITGTVDFIFGDASVVFQNCQILAKQGLPNQKNTITAQGRKDPNQPTGFSIQFCNISADADL-LPFVNSTPTYLGRPWKLYSRTIIMQSYIGNAVRPQGWLEWNQDFALDTLYYAEFMNFGPGAGLGGRVQWPGYHALNNSAQAGNFTVARLIEGDLWLPSTGVKYTAGLG 513          

Query:  130 LKVSATEFAGSLKDTIDAVQQVASILSQFANA-FGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSN---QQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            LKV+ +EF G+++D +  +Q+V SILSQF  + FGD RL+NA+SDC+D+LD S+D L WS SA+QN KGK+NSTG ++SD+RTWLS+AL N +TC +GFEGT+ I   L+S GL Q+ S++ ELLTQV PN +   Q+   G+ PSWVK  DRKLLQA+GV+VD +VA DG+GNFT V DAV AAPDYSM+RYVIY+KRG Y ENVEIKKKKWNLMM+GDGM+ATII+GNRSF+DGWTTFRSATFAVSGRGFIARDI+F+NTAGPEKHQAVALRSDSDLSVFYRC I GYQD+LYTHTMRQF+R+CKISGTVDFIFGDAT +FQNCQIL KKGLPNQKN+ITA GRKDPNEPTG SIQFCNITAD+DL   SVNST TYLGRPWK YSRT+ MQS +S+V+RPEGWLEWNGDFAL++L+Y EYMNYG GAGL  RVKWPGY + N+S+QA N+TV QFIEGNLWLP+TGV +TA  GV
Sbjct:   51 LKVAPSEFVGTVQDVVGILQEVMSILSQFGGSGFGDSRLSNAVSDCIDMLDLSSDALTWSASAAQNPKGKHNSTGNVNSDVRTWLSSALANPETCMDGFEGTSGIESQLVSTGLSQMMSMLAELLTQVDPNLDSFTQKEQKGRFPSWVKRDDRKLLQANGVNVDVVVATDGSGNFTKVMDAVHAAPDYSMKRYVIYVKRGVYIENVEIKKKKWNLMMVGDGMNATIITGNRSFIDGWTTFRSATFAVSGRGFIARDISFQNTAGPEKHQAVALRSDSDLSVFYRCGIFGYQDSLYTHTMRQFFRECKISGTVDFIFGDATTLFQNCQILVKKGLPNQKNTITAHGRKDPNEPTGFSIQFCNITADTDL-LPSVNSTYTYLGRPWKEYSRTIFMQSHISDVLRPEGWLEWNGDFALDTLYYAEYMNYGSGAGLNKRVKWPGYHIMNDSSQASNFTVTQFIEGNLWLPTTGVAFTAGLGV 527          

Query:  115 LQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVH---PNSNQQGPNGQI--------PSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            LQ+QCL V ++ F  SLK TID ++   S++SQF   F DFRL+NAISDCL+LLDF+AD+L+WSLSA QN KGK+N TG L SDL+TWLS+   NQDTC  GF GTN IV+ +++  L QV SLV  LLT VH   P     G  G +        PSWV    RKLLQA  VS D  VA DGTGN+T V DAV AAPDYS   YVIYIK+G YRENVEIKKKKWNLMM+GDGM AT+I+GNRS++DGWTT+ SATFAV G+GFIARD+TFENTAGPEKHQAVALRSDSDLSV+YRC++RGYQDTLY HT RQFYR+C+ISGTVDFIFGDATVVFQNCQIL KKGLPNQKN+ITAQGRKDP +PTG SIQF NI+ADSDL  ASVNST +YLGRPWK YSRT+IM+S++S+ IRPEGWLEWNGDFAL++L+YGEYMNYGP AGLGSRV+WPG+ + N S QA N+TV +FI GNLWLPSTGVKY+A   V
Sbjct:   43 LQSQCLAVPSSAFISSLKSTIDVLRGTMSVVSQFTKVFNDFRLSNAISDCLELLDFAADDLSWSLSAIQNPKGKDNGTGDLGSDLKTWLSSTFTNQDTCIEGFVGTNGIVKTVVAESLSQVASLVHSLLTMVHDPAPKGKSNGGGGGVKHVGSGDFPSWVGKHSRKLLQASSVSPDVTVAADGTGNYTTVMDAVQAAPDYSQNHYVIYIKQGIYRENVEIKKKKWNLMMVGDGMGATVITGNRSYIDGWTTYASATFAVKGKGFIARDMTFENTAGPEKHQAVALRSDSDLSVYYRCSMRGYQDTLYPHTNRQFYRECRISGTVDFIFGDATVVFQNCQILVKKGLPNQKNTITAQGRKDPAQPTGFSIQFSNISADSDL-LASVNSTLSYLGRPWKQYSRTIIMKSYISDAIRPEGWLEWNGDFALDTLYYGEYMNYGPSAGLGSRVQWPGFHLLNNSAQAANFTVTEFIAGNLWLPSTGVKYSAGLAV 531          

Query:    1 MASHNPLPAGKQXXXXXXXXXXXXXXXXXXXXXXXTDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            MASHNPLPAGKQ                       TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTY+ENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV
Sbjct:    6 MASHNPLPAGKQLLLLVLLCAFFSSSFIPFASCSITDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYKENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 522          

Query:  109 DDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQ----------GPNG---------------QIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            ++ Q   LKV A+EF  S+   +  ++QV+SILSQFA+  GD RL NA+SDCLDLLDFS++EL WS SAS+N KGK N TG + SD RTWLSAAL NQ TC  GF+GT+ +V+ L++  L Q+ S+++ELL  V P    +          GP                 Q P WV+  DRKLL+++G + D  VA DGTGNFT + DA+  APDYS  R+VIYIK+G Y ENVEIKKKKWN++M+GDG+D T+ISGNRSF+DGWTTFRSATFAVSGRGF+ARDITF+NTAGPEKHQAVALRSDSDLSVF+RC +RGYQDTLYTHTMRQFYR+C I+GTVDFIFGD TVVFQNCQILAK+GLPNQKN+ITAQGRKD N+P+G SIQF NI+AD+DL    +N+T TYLGRPWKLYSRTV +++ +S+V+RPEGWLEWN DFAL++LFYGE+MNYGPG+GL SRVKWPGY VFN S QA N+TV+QFI+GNLWLPSTGV ++
Sbjct:   21 ENFQYDYLKVPASEFVSSINTIVVVIRQVSSILSQFADFSGDRRLQNAVSDCLDLLDFSSEELTWSASASENPKGKGNGTGDVGSDTRTWLSAALSNQATCMEGFDGTSGLVKSLVAGSLDQLYSMLRELLPLVQPEQKPKAVSKPGPIAKGPKAPPGRKLRDTDEDESLQFPDWVRPDDRKLLESNGRTYDVSVALDGTGNFTKIMDAIKKAPDYSSTRFVIYIKKGLYLENVEIKKKKWNIVMLGDGIDVTVISGNRSFIDGWTTFRSATFAVSGRGFLARDITFQNTAGPEKHQAVALRSDSDLSVFFRCAMRGYQDTLYTHTMRQFYRECTITGTVDFIFGDGTVVFQNCQILAKRGLPNQKNTITAQGRKDVNQPSGFSIQFSNISADADL-VPYLNTTRTYLGRPWKLYSRTVFIRNNMSDVVRPEGWLEWNADFALDTLFYGEFMNYGPGSGLSSRVKWPGYHVFNNSDQANNFTVSQFIKGNLWLPSTGVTFS 520          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPN--------------GQIPSWVKTKDRKLLQADGVSV-DAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            TD +Q +CL+V   EFA + K  +DA+ +  +I+S+F    G  R++NAI DC+DLLD +A+EL+W +SASQ+  GK+NSTG + SDLRTW+SAAL NQDTC +GFEGTN I++ +++ GL +V + V+ LLT VH   ++  P                + PSWVK  DRKLLQ D ++V DA+VA DGTGNFT ++DAVLAAPDYS +RYVI++KRG Y ENVEIKKKKWN+MM+GDG+DAT+I+GNRSF+DGWTTFRSATFAVSGRGFIARDITF+NTAGPEKHQAVA+RSD+DL VFYRC +RGYQDTLY H+MRQF+R+C I+GTVDFIFGDAT VFQ+CQI AK+GLPNQKNSITAQGRKDPNEPTG +IQF NI AD+DL   ++N+T TYLGRPWKLYSRTV MQ+++S+ I P GWLEWNG+FAL++L+YGEYMN GPGA L  RVKWPGY V N S +A N+TV+Q I+GNLWLPSTG+ + A
Sbjct:   32 TDLVQMECLRVPPLEFAEAAKTVVDAITKAVAIVSKFDKKAGKSRVSNAIVDCVDLLDSAAEELSWIISASQSPNGKDNSTGDVGSDLRTWISAALSNQDTCLDGFEGTNGIIKKIVAGGLSKVGTTVRNLLTMVHSPPSKPKPKPIKAQTMTKAHSGFSKFPSWVKPGDRKLLQTDNITVADAVVAADGTGNFTTISDAVLAAPDYSTKRYVIHVKRGVYVENVEIKKKKWNIMMVGDGIDATVITGNRSFIDGWTTFRSATFAVSGRGFIARDITFQNTAGPEKHQAVAIRSDTDLGVFYRCAMRGYQDTLYAHSMRQFFRECIITGTVDFIFGDATAVFQSCQIKAKQGLPNQKNSITAQGRKDPNEPTGFTIQFSNIAADTDL-LLNLNTTATYLGRPWKLYSRTVFMQNYMSDAINPVGWLEWNGNFALDTLYYGEYMNSGPGASLDRRVKWPGYHVLNTSAEANNFTVSQLIQGNLWLPSTGITFIA 523          

Query:  163 LKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEG-TNSIVQGLISAGLGQVTSLVQELLTQVH-PNSNQQGPN-GQIPSWVKTKDRKLLQADG--VSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            L + +  +     ++S+  N   D R   A++DCL+LLD S D ++ S++A   +      T    ++ ++WLS  L N  TC +  +  T +++ G     L     +   +L  V  PN +   P  G++PSWV ++DRKL+++ G  +  +A+VA+DGTG +  + +AV AAPD S  RYVIY+KRG Y+ENVE+  +K  LM++GDGM ATII+GN + VDG TTF SAT A  G+GFI +DI  +NTAGP KHQAVALR  +D SV  RC I  YQDTLY H+ RQFYRD  ++GT+DFIFG+A VVFQ C+++A+K    Q+N +TAQGR DPN+ TG SIQFCNI A SDLE   +   PTYLGRPWK YSRTV+M+S+L  +I P GW EW+GDFAL +L+YGE+MN GPGAG   RVKWPGY    +  +A  +TVA+ I+G  WL STGV Y
Sbjct:   90 LVNYVHQMNNAIPVVSKMKNQINDIRQEGALTDCLELLDQSVDLVSDSIAAIDKR------THSEHANAQSWLSGVLTNHVTCLDELDSFTKAMINGTNLDELISRAKVALAMLASVTTPNDDVLRPGLGKMPSWVSSRDRKLMESSGKDIGANAVVAKDGTGKYRTLAEAVAAAPDKSKTRYVIYVKRGIYKENVEVSSRKMKLMIVGDGMHATIITGNLNVVDGSTTFHSATLAAVGKGFILQDICIQNTAGPAKHQAVALRVGADKSVINRCRIDAYQDTLYAHSQRQFYRDSYVTGTIDFIFGNAAVVFQKCKLVARKPGKYQQNMVTAQGRTDPNQATGTSIQFCNIIASSDLEPV-LKEFPTYLGRPWKKYSRTVVMESYLGGLINPAGWAEWDGDFALKTLYYGEFMNNGPGAGTSKRVKWPGYHCITDPAEAMPFTVAKLIQGGSWLRSTGVAY 544          

Query:  172 TIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEG-TNSIVQGLISAGLGQVTSLVQELLTQVH-PNSNQQGPN-GQIPSWVKTKDRKLLQADG--VSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            ++  +     ++ +  N   D R   A++DCL+LLD S D +  S++A   +    ++  +      +WLS  L N  TC +  +  T +++ G     L     +   +L  V  PN     P  G++PSWV ++DRKL+++ G  +  +A+VA+DGTG +  + +AV AAPD S  RYVIY+KRGTY+ENVE+  +K NLM+IGDGM ATII+G+ + VDG TTF SAT A  G+GFI +DI  +NTAGP KHQAVALR  +D SV  RC I  YQDTLY H+ RQFYRD  ++GT+DFIFG+A VVFQ CQ++A+K    Q+N +TAQGR DPN+ TG SIQFC+I A  DL+   V   PTYLGRPWK YSRTV+M+S+L  +I P GW EW+GDFAL +L+YGE+MN GPGAG   RVKWPGY V  +  +A ++TVA+ I+G  WL ST V Y
Sbjct:   93 SVHQMNNAIPVVRKIKNQINDIREQGALTDCLELLDLSVDLVCDSIAAIDKRSRSEHANAQ------SWLSGVLTNHVTCLDELDSFTKAMINGTNLDELISRAKVALAMLASVTTPNDEVLRPGLGKMPSWVSSRDRKLMESSGKDIGANAVVAKDGTGKYRTLAEAVAAAPDKSKTRYVIYVKRGTYKENVEVSSRKMNLMIIGDGMYATIITGSLNVVDGSTTFHSATLAAVGKGFILQDICIQNTAGPAKHQAVALRVGADKSVINRCRIDAYQDTLYAHSQRQFYRDSYVTGTIDFIFGNAAVVFQKCQLVARKPGKYQQNMVTAQGRTDPNQATGTSIQFCDIIASPDLKPV-VKEFPTYLGRPWKKYSRTVVMESYLGGLIDPSGWAEWHGDFALKTLYYGEFMNNGPGAGTSKRVKWPGYHVITDPAEAMSFTVAKLIQGGSWLRSTDVAY 544          

Query:  163 LKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEG-TNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPN-----GQIPSWVKTKDRKLLQADGVSV--DAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            L + +  +     ++ +  N   D R   A++DCL+LLD S D  + S++A   +    ++  +      +WLS  L N  TC +  +  T +++ G     L ++ S  +  L  +   + Q         G++PSWV + DRKL+++ G  +  +A+VAQDGTG++  + +AV AAPD S  RYVIY+KRGTY+ENVE+   K NLM++GDGM AT I+G+ + VDG TTFRSAT A  G+GFI +DI  +NTAGP K QAVALR  +D+SV  RC I  YQDTLY H+ RQFYRD  ++GTVDFIFG+A VVFQ CQ++A+K    Q+N +TAQGR DPN+ TG SIQFCNI A SDLE   +   PTYLGRPWK YSRTV+M+S+L  +I P GW EW+GDFAL +L+YGE+MN GPGAG   RVKWPGY V  +  +A  +TVA+ I+G  WL STGV Y
Sbjct:   86 LVNYVHQMNNAIPVVRKMKNQINDIRQHGALTDCLELLDQSVDFASDSIAAIDKRSRSEHANAQ------SWLSGVLTNHVTCLDELDSFTKAMING---TNLEELISRAKVALAMLASLTTQDEDVFMTVLGKMPSWVSSMDRKLMESSGKDIIANAVVAQDGTGDYQTLAEAVAAAPDKSKTRYVIYVKRGTYKENVEVASNKMNLMIVGDGMYATTITGSLNVVDGSTTFRSATLAAVGQGFILQDICIQNTAGPAKDQAVALRVGADMSVINRCRIDAYQDTLYAHSQRQFYRDSYVTGTVDFIFGNAAVVFQKCQLVARKPGKYQQNMVTAQGRTDPNQATGTSIQFCNIIASSDLEPV-LKEFPTYLGRPWKEYSRTVVMESYLGGLINPAGWAEWDGDFALKTLYYGEFMNNGPGAGTSKRVKWPGYHVITDPAKAMPFTVAKLIQGGSWLRSTGVAY 540          

Query:  250 AISDCLDLLDFSADELNWSLSASQNQKGK--------NNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELL---TQVHPNSNQQGPNGQI---PSWVKTKDRKLLQADGVSV---DAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            AI DC +L+ FS  EL WS+       G         ++       +L+TWLSAA+ NQDTC  GFEGT    + LI   L QVT LV  +L   TQ++    +   N  +   P W+   D  L+     SV   + +VA DG G +  + +A+  AP++S +RYVIY+K+G Y+EN+++KKKK N+M++GDG+  TII+G+R+F+ G TTFR+AT AVSGRGFIA+DITF NTAGP+  QAVALR DSD S FYRC++ GYQDTLY H++RQFYRDC+I GT+DFIFG+   V QNC+I  +  LP QK +ITAQGRK PN+ TG  IQ   + A          + PTYLGRPWKLYSRTV M +++S +++P GWLEW G+FAL++L+YGEY N GPG     RVKWPGY + ++ T A ++TV  FI+G  WLP+TGV +TA
Sbjct:  104 AIEDCKELVGFSVTELAWSMLEMNKLHGGGGIDLDDGSHDAAAAGGNLKTWLSAAMSNQDTCLEGFEGTERKYEELIKGSLRQVTQLVSNVLDMYTQLNALPFKASRNESVIASPEWLTETDESLMMRHDPSVMHPNTVVAIDGKGKYRTINEAINEAPNHSTKRYVIYVKKGVYKENIDLKKKKTNIMLVGDGIGQTIITGDRNFMQGLTTFRTATVAVSGRGFIAKDITFRNTAGPQNRQAVALRVDSDQSAFYRCSVEGYQDTLYAHSLRQFYRDCEIYGTIDFIFGNGAAVLQNCKIYTRVPLPLQKVTITAQGRKSPNQNTGFVIQNSYVLA----------TQPTYLGRPWKLYSRTVYMNTYMSQLVQPRGWLEWFGNFALDTLWYGEYNNIGPGWRSSGRVKWPGYHIMDKRT-ALSFTVGSFIDGRRWLPATGVTFTA 539          

Query:  238 RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGF---EGTNSIVQGLISAGLGQVTSLVQELLT------------QVHPNSNQQGPNG--QIPSWVKTKDRKLL--QADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRE-NVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            R+ +A   CL+LLD S D L  +LS+     G  +      SD+ TWLS+A+ N DTC++GF   EG    V+  +   +  ++ +V   L              V  N    G     ++P+W+K +DR+LL      +  D  V++DG+G F  + +A+  AP++S RR+VIY+K G Y E N+++ +KK NLM IGDG   T+I+G +S  D  TTF +ATFA +G GFI RD+TFEN AGP KHQAVALR   D +V YRCNI GYQD LY H+ RQF+R+C+I GTVDFIFG+A V+ Q+C I A+K +  QK +ITAQ RKDPN+ TGISI  C + A  DLE AS  S PTYLGRPWKLYSR V M S + + I P GWLEWNG FAL+SL+YGEYMN G G+G+G RVKWPGY V   + +A  +TVAQFI G+ WLPSTGV +
Sbjct:  136 RVRSAYDSCLELLDDSVDALTRALSSVVVVSGDESH-----SDVMTWLSSAMTNHDTCTDGFDEIEGQGGEVKDQVIGAVKDLSEMVSNCLAIFAGKVKDLSGVPVVNNRKLLGTEETEELPNWLKREDRELLGTPTSAIQADITVSKDGSGTFKTIAEAIKKAPEHSSRRFVIYVKAGRYEEENLKVGRKKTNLMFIGDGKGKTVITGGKSIADDLTTFHTATFAATGAGFIVRDMTFENYAGPAKHQAVALRVGGDHAVVYRCNIIGYQDALYVHSNRQFFRECEIYGTVDFIFGNAAVILQSCNIYARKPMAQQKITITAQNRKDPNQNTGISIHACKLLATPDLE-ASKGSYPTYLGRPWKLYSRVVYMMSDMGDHIDPRGWLEWNGPFALDSLYYGEYMNKGLGSGIGQRVKWPGYHVITSTVEASKFTVAQFISGSSWLPSTGVSF 581          

Query:  139 SATEFAGSL-----KDTIDAVQQVA------SILSQFANAFGDF--RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSI-VQGLISAGLGQVTSLVQELL---TQVHPNSNQQGPNGQ-------------IPSWVKTKDRKLLQ--ADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYREN-VEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            S  +F GSL     KD I     +       ++ S  + +F D   R  +A   C++LLD S D L+ +LS+  +   K         D+ TWLSAAL N DTC+ GF+G +   V+  ++A L  ++ LV   L   +  H   +  G   Q              P W++ K+R++L+     +  D IV++DG G    +++A+  AP  S RR +IY+K G Y EN +++ +KK NLM +GDG   T+ISG +S  D  TTF +A+FA +G GFIARDITFEN AGP KHQAVALR  +D +V YRCNI GYQDTLY H+ RQF+R+C I GTVDFIFG+A VV QNC I A+K +  QKN+ITAQ RKDPN+ TGISI    + A SDL+A +  ST TYLGRPWKL+SRTV M S++   +   GWLEWN  FAL++L+YGEY+N GPG+GLG RV WPGY+V N + +A  +TVA+FI G+ WLPSTGV + A   +
Sbjct:  103 SLMDFPGSLAASSSKDLIHVTVNMTLHHFSHALYSSASLSFVDMPPRARSAYDSCVELLDDSVDALSRALSSVVSSSAK-------PQDVTTWLSAALTNHDTCTEGFDGVDDGGVKDHMTAALQNLSELVSNCLAIFSASHDGDDFAGVPIQNRRLLGVEEREEKFPRWMRPKEREILEMPVSQIQADIIVSKDGNGTCKTISEAIKKAPQNSTRRIIIYVKAGRYEENNLKVGRKKINLMFVGDGKGKTVISGGKSIFDNITTFHTASFAATGAGFIARDITFENWAGPAKHQAVALRIGADHAVIYRCNIIGYQDTLYVHSNRQFFRECDIYGTVDFIFGNAAVVLQNCSIYARKPMDFQKNTITAQNRKDPNQNTGISIHASRVLAASDLQATN-GSTQTYLGRPWKLFSRTVYMMSYIGGHVHTRGWLEWNTTFALDTLYYGEYLNSGPGSGLGQRVSWPGYRVINSTAEANRFTVAEFIYGSSWLPSTGVSFLAGLSI 598          

Query:  202 ILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTN-SIVQGLISAGLGQVTSLVQELLTQVH-PNSN--QQGPNGQIPSWVKTKDRKLLQADGVSVDA--IVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            ++ +  N   D R   A++DCL+LLD S D ++ S++A   +    ++  +      +WLS  L N  TC +     + S   G +   L     +   +L  V  PN    +QG  G++P WV ++DRKL+++ G  + A  +VAQDGTG++  + +AV AAPD +  RYVIY+K G Y+ENV + KKK NLM++GDGM+ATII+G+ + VDG +TF S T A  G+GFI +DI  +NTAGPEK QAVALR  +D+SV  RC I  YQDTLY H+ RQFYRD  ++GTVDFIFG+A VVFQ CQI+A+K    QKN +TAQGR DPN+ TG SIQFC+I A  DLE   +N   TYLGRPWK +SRTV+MQS+L   I P GW EW GDFAL +L+YGE+MN GPGAG   RVKWPGY V  +  +A  +TVA+ I+G  WL ST V Y
Sbjct:   98 VVRKIKNQINDIRQQGALTDCLELLDQSVDLVSDSIAAIDKRSRSEHANAQ------SWLSGVLTNHVTCLDELTSFSLSTKNGTVLDELITRAKVALAMLASVTTPNDEVLRQGL-GKMPYWVSSRDRKLMESSGKDIIANRVVAQDGTGDYQTLAEAVAAAPDKNKTRYVIYVKMGIYKENVVVTKKKMNLMIVGDGMNATIITGSLNVVDG-STFPSNTLAAVGQGFILQDICIQNTAGPEKDQAVALRVGADMSVINRCRIDAYQDTLYAHSQRQFYRDSYVTGTVDFIFGNAAVVFQKCQIVARKPNKRQKNMVTAQGRTDPNQATGTSIQFCDIIASPDLEPV-MNEYKTYLGRPWKKHSRTVVMQSYLDGHIDPSGWFEWRGDFALKTLYYGEFMNNGPGAGTSKRVKWPGYHVITDPNEAMPFTVAELIQGGSWLNSTSVAY 538          

Query:  109 DDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQ----------GPNG---------------QIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            ++ Q   LKV A+EF  S+   +  ++QV+SILSQFA+  GD RL NA+SDCLDLLDFS++EL WS SAS+N KGK N TG + SD RTWLSAAL NQ TC  GF+GT+ +V+ L++  L Q+ S+++ELL  V P    +          GP                 Q P WV+  DRKLL+++G + D  VA DGTGNFT + DA+  APDYS  R+VIYIK+G Y ENVEIKKKKWN++M+GDG+D T+ISGNRSF+DGWTTFRSATFAVSGRGF+ARDITF+NTAGPEKHQAVALRSDSDLSVF+RC +RGYQDTLYTHTMRQFYR+C I+GTVDFIFGD TVVFQNCQILAK+GLPNQKN+ITAQGRKD N+P+G SIQF NI+AD+DL    +N+T TYLGRPWKLYSRTV +++ +S+V+RPEGWLEWN DFAL++LFYGE+MNYGPG+GL SRVKWPGY VFN S QA N+TV+QFI+GNLWLPSTGV ++
Sbjct:   21 ENFQYDYLKVPASEFVSSINTIVVVIRQVSSILSQFADFSGDRRLQNAVSDCLDLLDFSSEELTWSASASENPKGKGNGTGDVGSDTRTWLSAALSNQATCMEGFDGTSGLVKSLVAGSLDQLYSMLRELLPLVQPEQKPKAVSKPGPIAKGPKAPPGRKLRDTDEDESLQFPDWVRPDDRKLLESNGRTYDVSVALDGTGNFTKIMDAIKKAPDYSSTRFVIYIKKGLYLENVEIKKKKWNIVMLGDGIDVTVISGNRSFIDGWTTFRSATFAVSGRGFLARDITFQNTAGPEKHQAVALRSDSDLSVFFRCAMRGYQDTLYTHTMRQFYRECTITGTVDFIFGDGTVVFQNCQILAKRGLPNQKNTITAQGRKDVNQPSGFSIQFSNISADADL-VPYLNTTRTYLGRPWKLYSRTVFIRNNMSDVVRPEGWLEWNADFALDTLFYGEFMNYGPGSGLSSRVKWPGYHVFNNSDQANNFTVSQFIKGNLWLPSTGVTFS 520          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPN--------------GQIPSWVKTKDRKLLQADGVSV-DAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            TD +Q +CL+V   EFA + K  +DA+ +  +I+S+F    G  R++NAI DC+DLLD +A+EL+W +SASQ+  GK+NSTG + SDLRTW+SAAL NQDTC +GFEGTN I++ +++ GL +V + V+ LLT VH   ++  P                + PSWVK  DRKLLQ D ++V DA+VA DGTGNFT ++DAVLAAPDYS +RYVI++KRG Y ENVEIKKKKWN+MM+GDG+DAT+I+GNRSF+DGWTTFRSATFAVSGRGFIARDITF+NTAGPEKHQAVA+RSD+DL VFYRC +RGYQDTLY H+MRQF+R+C I+GTVDFIFGDAT VFQ+CQI AK+GLPNQKNSITAQGRKDPNEPTG +IQF NI AD+DL   ++N+T TYLGRPWKLYSRTV MQ+++S+ I P GWLEWNG+FAL++L+YGEYMN GPGA L  RVKWPGY V N S +A N+TV+Q I+GNLWLPSTG+ + A
Sbjct:   32 TDLVQMECLRVPPLEFAEAAKTVVDAITKAVAIVSKFDKKAGKSRVSNAIVDCVDLLDSAAEELSWIISASQSPNGKDNSTGDVGSDLRTWISAALSNQDTCLDGFEGTNGIIKKIVAGGLSKVGTTVRNLLTMVHSPPSKPKPKPIKAQTMTKAHSGFSKFPSWVKPGDRKLLQTDNITVADAVVAADGTGNFTTISDAVLAAPDYSTKRYVIHVKRGVYVENVEIKKKKWNIMMVGDGIDATVITGNRSFIDGWTTFRSATFAVSGRGFIARDITFQNTAGPEKHQAVAIRSDTDLGVFYRCAMRGYQDTLYAHSMRQFFRECIITGTVDFIFGDATAVFQSCQIKAKQGLPNQKNSITAQGRKDPNEPTGFTIQFSNIAADTDL-LLNLNTTATYLGRPWKLYSRTVFMQNYMSDAINPVGWLEWNGNFALDTLYYGEYMNSGPGASLDRRVKWPGYHVLNTSAEANNFTVSQLIQGNLWLPSTGITFIA 523          

Query:  250 AISDCLDLLDFSADELNWSLSASQNQKGK--------NNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELL---TQVHPNSNQQGPNGQI---PSWVKTKDRKLLQADGVSV---DAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            AI DC +L+ FS  EL WS+       G         ++       +L+TWLSAA+ NQDTC  GFEGT    + LI   L QVT LV  +L   TQ++    +   N  +   P W+   D  L+     SV   + +VA DG G +  + +A+  AP++S +RYVIY+K+G Y+EN+++KKKK N+M++GDG+  TII+G+R+F+ G TTFR+AT AVSGRGFIA+DITF NTAGP+  QAVALR DSD S FYRC++ GYQDTLY H++RQFYRDC+I GT+DFIFG+   V QNC+I  +  LP QK +ITAQGRK PN+ TG  IQ   + A          + PTYLGRPWKLYSRTV M +++S +++P GWLEW G+FAL++L+YGEY N GPG     RVKWPGY + ++ T A ++TV  FI+G  WLP+TGV +TA
Sbjct:  104 AIEDCKELVGFSVTELAWSMLEMNKLHGGGGIDLDDGSHDAAAAGGNLKTWLSAAMSNQDTCLEGFEGTERKYEELIKGSLRQVTQLVSNVLDMYTQLNALPFKASRNESVIASPEWLTETDESLMMRHDPSVMHPNTVVAIDGKGKYRTINEAINEAPNHSTKRYVIYVKKGVYKENIDLKKKKTNIMLVGDGIGQTIITGDRNFMQGLTTFRTATVAVSGRGFIAKDITFRNTAGPQNRQAVALRVDSDQSAFYRCSVEGYQDTLYAHSLRQFYRDCEIYGTIDFIFGNGAAVLQNCKIYTRVPLPLQKVTITAQGRKSPNQNTGFVIQNSYVLA----------TQPTYLGRPWKLYSRTVYMNTYMSQLVQPRGWLEWFGNFALDTLWYGEYNNIGPGWRSSGRVKWPGYHIMDKRT-ALSFTVGSFIDGRRWLPATGVTFTA 539          

Query:  238 RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGF---EGTNSIVQGLISAGLGQVTSLVQELLT------------QVHPNSNQQGPNG--QIPSWVKTKDRKLL--QADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRE-NVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            R+ +A   CL+LLD S D L  +LS+     G  +      SD+ TWLS+A+ N DTC++GF   EG    V+  +   +  ++ +V   L              V  N    G     ++P+W+K +DR+LL      +  D  V++DG+G F  + +A+  AP++S RR+VIY+K G Y E N+++ +KK NLM IGDG   T+I+G +S  D  TTF +ATFA +G GFI RD+TFEN AGP KHQAVALR   D +V YRCNI GYQD LY H+ RQF+R+C+I GTVDFIFG+A V+ Q+C I A+K +  QK +ITAQ RKDPN+ TGISI  C + A  DLE AS  S PTYLGRPWKLYSR V M S + + I P GWLEWNG FAL+SL+YGEYMN G G+G+G RVKWPGY V   + +A  +TVAQFI G+ WLPSTGV +
Sbjct:  136 RVRSAYDSCLELLDDSVDALTRALSSVVVVSGDESH-----SDVMTWLSSAMTNHDTCTDGFDEIEGQGGEVKDQVIGAVKDLSEMVSNCLAIFAGKVKDLSGVPVVNNRKLLGTEETEELPNWLKREDRELLGTPTSAIQADITVSKDGSGTFKTIAEAIKKAPEHSSRRFVIYVKAGRYEEENLKVGRKKTNLMFIGDGKGKTVITGGKSIADDLTTFHTATFAATGAGFIVRDMTFENYAGPAKHQAVALRVGGDHAVVYRCNIIGYQDALYVHSNRQFFRECEIYGTVDFIFGNAAVILQSCNIYARKPMAQQKITITAQNRKDPNQNTGISIHACKLLATPDLE-ASKGSYPTYLGRPWKLYSRVVYMMSDMGDHIDPRGWLEWNGPFALDSLYYGEYMNKGLGSGIGQRVKWPGYHVITSTVEASKFTVAQFISGSSWLPSTGVSF 581          

Query:  139 SATEFAGSL-----KDTIDAVQQVA------SILSQFANAFGDF--RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSI-VQGLISAGLGQVTSLVQELL---TQVHPNSNQQGPNGQ-------------IPSWVKTKDRKLLQ--ADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYREN-VEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            S  +F GSL     KD I     +       ++ S  + +F D   R  +A   C++LLD S D L+ +LS+  +   K         D+ TWLSAAL N DTC+ GF+G +   V+  ++A L  ++ LV   L   +  H   +  G   Q              P W++ K+R++L+     +  D IV++DG G    +++A+  AP  S RR +IY+K G Y EN +++ +KK NLM +GDG   T+ISG +S  D  TTF +A+FA +G GFIARDITFEN AGP KHQAVALR  +D +V YRCNI GYQDTLY H+ RQF+R+C I GTVDFIFG+A VV QNC I A+K +  QKN+ITAQ RKDPN+ TGISI    + A SDL+A +  ST TYLGRPWKL+SRTV M S++   +   GWLEWN  FAL++L+YGEY+N GPG+GLG RV WPGY+V N + +A  +TVA+FI G+ WLPSTGV + A   +
Sbjct:  103 SLMDFPGSLAASSSKDLIHVTVNMTLHHFSHALYSSASLSFVDMPPRARSAYDSCVELLDDSVDALSRALSSVVSSSAK-------PQDVTTWLSAALTNHDTCTEGFDGVDDGGVKDHMTAALQNLSELVSNCLAIFSASHDGDDFAGVPIQNRRLLGVEEREEKFPRWMRPKEREILEMPVSQIQADIIVSKDGNGTCKTISEAIKKAPQNSTRRIIIYVKAGRYEENNLKVGRKKINLMFVGDGKGKTVISGGKSIFDNITTFHTASFAATGAGFIARDITFENWAGPAKHQAVALRIGADHAVIYRCNIIGYQDTLYVHSNRQFFRECDIYGTVDFIFGNAAVVLQNCSIYARKPMDFQKNTITAQNRKDPNQNTGISIHASRVLAASDLQATN-GSTQTYLGRPWKLFSRTVYMMSYIGGHVHTRGWLEWNTTFALDTLYYGEYLNSGPGSGLGQRVSWPGYRVINSTAEANRFTVAEFIYGSSWLPSTGVSFLAGLSI 598          

Query:  163 LKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLT---QVHPNSNQQGP--NGQIPSWVKTKDRKLLQADG----VSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            LK+++  ++   +++S+        R     +DC +++D S D +   +S+ +  +G N +    S+ + TWLS+ L N  TC       +   + ++   L  + S  +  L     V P  +      + + PSW+   DRKLL++      V+ + +VA+DGTG F  V +AV AAP+ S  RYVIY+K+G Y+E ++I KKK NLM++GDG DATII+G+ + +DG TTFRSAT A +G GF+A+DI F+NTAGP KHQAVALR  +D +V  RC I  YQDTLYTHT+RQFYRD  I+GTVDFIFG++ VVFQNC I+A+     QKN +TAQGR+D N+ T ISIQ C ITA SDL A    S  T+LGRPWKLYSRTVIMQSF+ N I P GW  W+G+FAL++L+YGEY N GPGA    RV W G++V  +S +A+ +TVA+ I+G LWL  TGV +
Sbjct:   93 LKNSVWRLESTMTMVSEARIRSNGVRDKAGFADCEEMMDVSKDRM---MSSMEELRGGNYNLESYSN-VHTWLSSVLTNYMTCLESISDVSVNSKQIVKPQLEDLVSRARVALAIFVSVLPARDDLKMIISNRFPSWLTALDRKLLESSPKTLKVTANVVVAKDGTGKFKTVNEAVAAAPENSNTRYVIYVKKGVYKETIDIGKKKKNLMLVGDGKDATIITGSLNVIDGSTTFRSATVAANGDGFMAQDIWFQNTAGPAKHQAVALRVSADQTVINRCRIDAYQDTLYTHTLRQFYRDSYITGTVDFIFGNSAVVFQNCDIVARNPGAGQKNMLTAQGREDQNQNTAISIQKCKITASSDL-APVKGSVKTFLGRPWKLYSRTVIMQSFIDNHIDPAGWFPWDGEFALSTLYYGEYANTGPGADTSKRVNWKGFKVIKDSKEAEQFTVAKLIQGGLWLKPTGVTF 553          

Query:  238 RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGF--EGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQI---------------------------PSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            R   A+ DCL+ +D + DEL+ ++    +Q  K  S  K + DL+T +S+A+ NQ TC +GF  +  +  V+  +  G   V  +    L  +   +     N ++                           P W+   DR+LLQ   +  DA VA DG+G+FT V  AV AAP+ S +R+VI+IK G YRENVE+ KKK N+M +GDG   TII+G+R+ VDG TTF SAT A  G  F+ARDITF+NTAGP KHQAVALR  SD S FY+C++  YQDTLY H+ RQF+  C I+GTVDFIFG+A  V Q+C I A++    QKN +TAQGR DPN+ TGI IQ C I   SDL A    + PTYLGRPWK YSRTVIMQS +S+VIRPEGW EW+G FAL++L Y EY+N G GAG  +RVKW GY+V    T+A+ +T  QFI G  WL STG  ++
Sbjct:  125 REVTALHDCLETIDETLDELHVAVE-DLHQYPKQKSLRKHADDLKTLISSAITNQGTCLDGFSYDDADRKVRKALLKGQVHVEHMCSNALAMIKNMTETDIANFELRDKSSTFTNNNNRKLKEVTGDLDSDGWPKWLSVGDRRLLQGSTIKADATVADDGSGDFTTVAAAVAAAPEKSNKRFVIHIKAGVYRENVEVTKKKTNIMFLGDGRGKTIITGSRNVVDGSTTFHSATVAAVGERFLARDITFQNTAGPSKHQAVALRVGSDFSAFYQCDMFAYQDTLYVHSNRQFFVKCHITGTVDFIFGNAAAVLQDCDINARRPNSGQKNMVTAQGRSDPNQNTGIVIQNCRIGGTSDLLAVK-GTFPTYLGRPWKEYSRTVIMQSDISDVIRPEGWHEWSGSFALDTLTYREYLNRGGGAGTANRVKWKGYKVITSDTEAQPFTAGQFIGGGGWLASTGFPFS 584          

Query:  238 RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSI-------------VQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQI------------------------PSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            R   A+ DCL+ +D + DEL+ ++        K  +  + + DL+T +S+A+ NQ+TC +GF   ++              V+ + S  L  + ++    +      +     N ++                        P+W+   DR+LLQ  GV  DA VA DG+G F  V  AV AAP+ S +RYVI+IK G YRENVE+ KKK N+M +GDG   TII+G+R+ VDG TTF SAT A  G  F+ARDITF+NTAGP KHQAVALR  SD S FY C++  YQDTLY H+ RQF+  C I+GTVDFIFG+A VV Q+C I A++    QKN +TAQGR DPN+ TGI IQ C I A SDL++    S PTYLGRPWK YS+TVIMQS +S+VIRPEGW EW G FALN+L Y EY N G GAG  +RVKW G++V   + +A+ YT  QFI G  WL STG  ++
Sbjct:  122 REKTALHDCLETIDETLDELHETVEDLHLYPTKK-TLREHAGDLKTLISSAITNQETCLDGFSHDDADKQVRKALLKGQIHVEHMCSNALAMIKNMTDTDIANFEQKAKITSNNRKLKEENQETTVAVDIAGAGELDSEGWPTWLSAGDRRLLQGSGVKADATVAADGSGTFKTVAAAVAAAPENSNKRYVIHIKAGVYRENVEVAKKKKNIMFMGDGRTRTIITGSRNVVDGSTTFHSATVAAVGERFLARDITFQNTAGPSKHQAVALRVGSDFSAFYNCDMLAYQDTLYVHSNRQFFVKCLIAGTVDFIFGNAAVVLQDCDIHARRPNSGQKNMVTAQGRTDPNQNTGIVIQKCRIGATSDLQSVK-GSFPTYLGRPWKEYSQTVIMQSAISDVIRPEGWSEWTGTFALNTLTYREYSNTGAGAGTANRVKWRGFKVITAAAEAQKYTAGQFIGGGGWLSSTGFPFS 589          

Query:  163 LKDTIDAVQQVASILSQFANAFGDFRLA-NAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSS--DLRTWLSAALVNQDTCSNGFEG---TNSIVQGL-----------ISAGLGQVTSLVQ-ELLTQVHPN------SNQQGPNG-------------QIPSWVKTKDRKLLQADGVSV--DAIVAQDGTGNFTNVTDAVLAAPDYSMR--RYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGV 1527
            +  T+D   Q+  ++S         + A +A+ DCL+L + + D+LN S            S G+ SS  D +T LSAA+ NQDTC NGF     T+S  +             IS  L    +  + E + + +P+      S Q+   G             + PSW    DRKLL+    +   D +VA+DG+G++T++  AV AA     R  R VIY+K G YRENV IKK   N+M+IGDG+D+TI++GNR+  DG TTFRSATFAVSG GFIA+ ITFENTAGPEKHQAVALRS SD SVFY C+ +GYQDTLY H+ RQF R+C I GTVDFIFGDAT + QNC I A+K +  QKN+ITAQ RK+P+E TG  IQ   +   S+          TYLGRPW+ +SRTV M+  L  ++ P GWL W+G FAL++L+YGEY N G GA +  RVKWPGY V    T+A+ +TV  F++GN W+ +TGV
Sbjct:   73 VSSTMDQAVQLHRLVSSLKQHHSLHKHATSALFDCLELYEDTIDQLNHS----------RRSYGQYSSPHDRQTSLSAAIANQDTCRNGFRDFKLTSSYSKYFPVQFHRNLTKSISNSLAVTKAAAEAEAVAEKYPSTGFTKFSKQRSSAGGGSHRRLLLFSDEKFPSWFPLSDRKLLEDSKTTAKADLVVAKDGSGHYTSIQQAVNAAAKLPRRNQRLVIYVKAGVYRENVVIKKSIKNVMVIGDGIDSTIVTGNRNVQDGTTTFRSATFAVSGNGFIAQGITFENTAGPEKHQAVALRSSSDFSVFYACSFKGYQDTLYLHSSRQFLRNCNIYGTVDFIFGDATAILQNCNIYARKPMSGQKNTITAQSRKEPDETTGFVIQSSTVATASE----------TYLGRPWRSHSRTVFMKCNLGALVSPAGWLPWSGSFALSTLYYGEYGNTGAGASVSGRVKWPGYHVIKTVTEAEKFTVENFLDGNYWITATGV 548          

Query:  160 SLKDTIDAVQQVASILSQFANAFGD---FRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSI------------VQGLISAGLGQVTSLVQELLTQVH------PNSNQQGPNGQIPSWVKTKDRKLLQ--ADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAE 1542
            +L  TI  V   +S  S      G     R   A  DCL+LLD +  +L  ++S  ++   + ++   L       LSAA+ N  TC +GF  +++             V   +   L  ++S V + L  +       P   ++      P WV   DR LLQ   D   V+ +VAQ+GTGN+T + +A+ AAP+ S  R+VIYIK G Y EN+EI ++K  +M IGDG+  T+I  NRS+ DGWT F SAT  V G GFIA+D++F N AGPEKHQAVALRS SDLS +YRC+   YQDT+Y H+ +QFYR+C I GTVDFIFGDA+VVFQNC + A++  PNQK   TAQGR++  EPTGISI    I A  DL     N    YLGRPW+LYSRTVIM+SF+ +++ P GWL+W  DFAL +L+YGEYMN GPG+ + +RV+WPG++      +A  ++V  FI+GN WL ST + +T +
Sbjct:   44 ALNQTISNVNLSSSNFSDLLQRLGSNLSHRDLCAFDDCLELLDDTVFDLTTAISKLRSHSPELHNVKML-------LSAAMTNTRTCLDGFASSDNDENLNNNDNKTYGVAESLKESLFNISSHVSDSLAMLENIPGHIPGKVKEDVG--FPMWVSGSDRNLLQDPVDETKVNLVVAQNGTGNYTTIGEAISAAPNSSETRFVIYIKCGEYFENIEIPREKTMIMFIGDGIGRTVIKANRSYADGWTAFHSATVGVRGSGFIAKDLSFVNYAGPEKHQAVALRSSSDLSAYYRCSFESYQDTIYVHSHKQFYRECDIYGTVDFIFGDASVVFQNCSLYARRPNPNQKIIYTAQGRENSREPTGISIISSRILAAPDLIPVQAN-FKAYLGRPWQLYSRTVIMKSFIDDLVDPAGWLKWKDDFALETLYYGEYMNEGPGSNMTNRVQWPGFKRIETVEEASQFSVGPFIDGNKWLNSTRIPFTLD 517          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQ-----------GPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            TDDLQ  CLKV   +F GSL  T+D ++ V SI+S F N FGD RL NAI+DCLDLLDFSADEL+WS+SASQN  GK+NSTG LSSDLRTWLSAALVNQDTC  GF+GTN+I++GL+S  L Q+TS VQELL  V P++N +           G N + PSWVK +DRKLL  +GV+ + IVA DGTGNFT + DAV AAPDYSM R++IYIK+G Y E V+IKKKKWNLMM+G+GM+ATII+GNR+F+DGWTTFRSATFAVSGRGFIARDITFENTAGP KHQAVALRSDSDLSVF+RC I+ YQD+LYTHTMRQFYR+C++SGTVDFIFGDAT VFQNCQILA+KGLP+QKN++TA GRKDPN+PTG S QFCNI+AD DL    VNS+ TYLGRPWK +SRT+IMQS++SN IRPEGWLEWNG+  L++L+YGEY+NYGPGAG+G RV+WPG+ + N+STQA NYTVAQFI+GNLWLPSTGV+YTA
Sbjct:   37 TDDLQNNCLKVPVNQFVGSLTSTLDIIRDVISIISNFGNVFGDIRLTNAITDCLDLLDFSADELSWSMSASQNPNGKHNSTGDLSSDLRTWLSAALVNQDTCIEGFDGTNNILKGLVSGSLNQITSSVQELLKNVDPHTNSKSSGGGFSGSKSGNNDRFPSWVKHEDRKLLVLNGVTPNVIVAADGTGNFTKIMDAVAAAPDYSMHRHIIYIKKGVYNEYVDIKKKKWNLMMVGEGMNATIITGNRNFIDGWTTFRSATFAVSGRGFIARDITFENTAGPSKHQAVALRSDSDLSVFFRCEIKSYQDSLYTHTMRQFYRECRVSGTVDFIFGDATAVFQNCQILARKGLPDQKNTVTAHGRKDPNQPTGYSFQFCNISADIDL-LPYVNSSYTYLGRPWKNFSRTIIMQSYMSNAIRPEGWLEWNGNVYLDTLYYGEYINYGPGAGVGRRVRWPGFHMLNDSTQANNYTVAQFIQGNLWLPSTGVRYTA 524          

Query:  202 ILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELL---TQVH-----PNSNQQGP-----NGQIPSWVKTKDRKLLQAD--GVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            ++++F      +R   AI DC +LLDFS  EL WSL    N +    +      +L+ WLSAAL N DTC  GFEGT+  ++  I   L QVT L+  +L   TQ+H     P  N  G      + + P W+   D++LL+    G+ +DAIVA DGTG++  +T+A+  AP YS RRY+IY+K+G YREN+++K+KK N+M +GDG+  T+++GNR+F+ GWT+FR+AT AVSG+GFIARD+TF NTAGP  HQAVALR DSD S FYRC++ GYQDTLY H++RQFYR+C+I GT+D+IFG+   VFQNC+I  +  LP QK +ITAQGRK+P++ TG SIQ   I A          S PTYLGRPWK YSRTV M +++S +++P GWLEW G+FAL +L+YGEY N+GPGA L  RVKWPGY +  +   AK +T AQFI+G  WLPSTGVK+TA
Sbjct:    6 MITKFNALSVSYREQVAIEDCKELLDFSVSELAWSLKEMNNIRAGIKNV-HYEGNLKAWLSAALSNPDTCLEGFEGTDGHLENFIRGSLKQVTQLIGNVLALYTQLHSLPFKPPRNDNGTTTNSGSDKFPEWMTEGDQELLKGSSLGMHIDAIVAGDGTGHYRTITEAINEAPSYSNRRYIIYVKKGVYRENIDMKRKKSNIMFVGDGIGQTVVTGNRNFMQGWTSFRTATVAVSGKGFIARDMTFRNTAGPLNHQAVALRVDSDQSAFYRCSMEGYQDTLYAHSLRQFYRECEIYGTIDYIFGNGAAVFQNCKIYTRVPLPLQKVTITAQGRKNPHQSTGFSIQDSYIFA----------SQPTYLGRPWKQYSRTVFMNTYMSALVQPRGWLEWYGNFALGTLWYGEYRNHGPGALLSGRVKWPGYHIIQDVATAKFFTAAQFIDGLSWLPSTGVKFTA 455          

Query:  247 NAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVH----------PNSNQQ---------GPNGQIPSWVKTKDRKLL--QADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRE-NVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            +A  DCL+LL+ S D L  SLS      G   S      D+ TWLSAAL NQDTCS GFEG N  V+  ++  L  +T LV   L              P  N++               PSW+  ++R+LL      +  D IV+ DG+G F  +++A+  AP++S RR +IY++ G Y E N+++ +KKWNLM IGDGM  TII+G+RS  +  TTF +A+FA +G GFIARD+TFEN AGP KHQAVALR  +D +V YRC+I GYQDTLY H+ RQFYR+C I GTVDFIFG+A VV QNC I A+K + +QKN+ITAQ RKDPN+ TGISI  C I A SDL A S  + PTYLGRPWKLYSRTV M SF+ + I P GWLEW+  FAL++L+YGEYMNYGPGA +G RVKWPGY+V   + +A  +TVAQFI G+ WLPSTGV + A   V
Sbjct:  151 SAFDDCLELLEDSIDALTRSLSTVSPSSGGGGSP----EDVVTWLSAALTNQDTCSEGFEGVNGTVKDQMTEKLKDLTELVSNCLAIFSATNGGDFSGVPIQNKRRLMTEDGDISEEDNFPSWLGRRERRLLGLPVSAIQADIIVSGDGSGTFKTISEAIKKAPEHSNRRTIIYVRAGRYVEDNLKVGRKKWNLMFIGDGMGKTIITGSRSVFNHITTFHTASFAATGAGFIARDMTFENWAGPAKHQAVALRVGADHAVVYRCSIIGYQDTLYVHSNRQFYRECDIYGTVDFIFGNAAVVLQNCSIYARKPMASQKNTITAQNRKDPNQNTGISIHACKILAASDL-APSKGTFPTYLGRPWKLYSRTVYMLSFMGDHIHPRGWLEWDASFALDTLYYGEYMNYGPGAAVGQRVKWPGYRVITSTVEANKFTVAQFIYGSSWLPSTGVAFLAGLSV 602          

Query:  238 RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNG--------------------QIPSWVKTKDRKLLQAD--GVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYREN-VEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            R+ +A  DCL+LLD S D L+ SLS      G     G   +D+ TWLSAAL NQDTCS GF+G N  V+  ++  L  +T LV   L  +  ++N    +G                      P W+  +DRKLL      +  D IV+ DG G    +++A+  AP+YS RR VIY++ G Y EN +++ +KKWNLM IGDG   TIISG +S  +  TTF +A+FA +G GFIARD+TFEN AGP KHQAVALR  +D +V YRCNI GYQDTLY H+ RQF+R+C I GTVDFIFG+A VVFQNC I A+K +  QKN+ITAQ RKDPN+ TGISI  C I A SDL      S PT+LGRPWKLYSRTV M S++ + + P GWLEWN  FAL++L+YGEYMNYGPG  +G RVKWPGY+V   + +A  +TVAQFI G+ WLPSTGV + A
Sbjct:  148 RVRSAFDDCLELLDDSIDALSRSLSTVAPSHGGGTGGGS-PADVVTWLSAALTNQDTCSEGFDGVNGAVKNQMTGRLKDLTELVSNCLA-IFSSANGDDFSGVPVQNKRRLLTENEDISYEENFPRWLGRRDRKLLDVPVPAIHADIIVSGDGNGTCKTISEAIKKAPEYSTRRTVIYVRAGRYEENNLKVGRKKWNLMFIGDGKGKTIISGGKSVFNNLTTFHTASFAATGAGFIARDMTFENWAGPAKHQAVALRVGADHAVVYRCNIIGYQDTLYVHSNRQFFRECDIYGTVDFIFGNAAVVFQNCSIYARKPMAFQKNTITAQNRKDPNQNTGISIHACRILATSDLTPLK-GSFPTFLGRPWKLYSRTVYMLSYIGDHVHPRGWLEWNTTFALDTLYYGEYMNYGPGGAVGQRVKWPGYRVVTSTIEASKFTVAQFIYGSSWLPSTGVSFLA 601          

Query:  160 SLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFG 1548
            +L+ T+D  ++    +++F +    +R   AI DC +LLDFS  EL WSL    N+            +L+ WLSAAL N DTC  GFEGT+  ++  IS  + QVT L+  +L                                   DAIVA DG+G++  +T+A+  AP Y  RRY+IY+K G YREN+++K+KK  +M++GDG+  T+++GNR+F+ GWTTFR+AT AVSG+GFIARD+TF NTAGP  HQAVALR DSD S FYRC++ GYQDTLY H++RQFYR+C+I GT+D+IFG+   VFQ C+I  +  LP QK +ITAQGRK+P++ TG SIQ   I A          S PTYLGRPWK YSRTV M +++S +++P GWLEW G+FAL +L+YGEY N GPGA L  RVKWPGY +  ++  AK +TV QFI+G  WLPSTG+K+T   G
Sbjct:   73 ALRATLDEARRAIDTITKFNSLSISYREQVAIEDCKELLDFSVSELAWSLM-EMNKIRAGIKNVHYEGNLKAWLSAALSNPDTCLEGFEGTDRHLENFISGSIKQVTQLIGNVL-----------------------------------DAIVALDGSGHYRTITEAINEAPSYRTRRYIIYVKTGVYRENIDMKRKKSYIMLVGDGIGKTVVTGNRNFMQGWTTFRTATVAVSGKGFIARDMTFRNTAGPLNHQAVALRVDSDQSAFYRCSMEGYQDTLYAHSLRQFYRECEIHGTIDYIFGNGAAVFQECKIYTRVPLPLQKVTITAQGRKNPHQSTGFSIQNSYIFA----------SQPTYLGRPWKQYSRTVFMNTYMSALVQPRGWLEWYGNFALGTLWYGEYRNRGPGALLSGRVKWPGYHIIQDARTAKFFTVTQFIDGMSWLPSTGIKFTVGLG 489          

Query:  250 AISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFE-----GTNSIVQGLIS---AGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDA--IVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            A++DC++L+D S D +  +LSA  N   ++++     SD  TWLS  L N  TC +G +         ++Q LIS     L  V+SL       V P       NG  PSW+  +DRKLL++   +V+A  +VAQDG+G+ T + ++V + PD S  RYVI +K G Y+ENVE+ KKK N+M++GDGMD+TI++GN + VDG TTFRSAT AV+G GF+ +DI  +NTAGPEKHQAVALR  +D SV  RC I  YQDTLYTH  RQFYRDC I GT+DFIFG+  VV QNC I+++K + NQKN +TAQGR DPN+ TGISIQ C+I A SDLE+   N  PTYLGRPWK YSRTV+MQS +   I P GW EW+ +FAL +L+YGEY N G GAG+  RV WPGY V  +  +AK +TVA+ I+G  WL STGV +T
Sbjct:  121 ALADCVELMDMSIDRVTDTLSALANWGSQSDA-----SDANTWLSGVLTNHVTCLDGIDTIDQPSMKKLLQDLISRMRTSLAAVSSLSASDTDLVQPL------NGGFPSWILGRDRKLLESSVSTVEANVVVAQDGSGDNTTIQESVNSVPDKSKSRYVICVKSGIYKENVEVGKKKKNVMIVGDGMDSTILTGNLNVVDGSTTFRSATLAVAGDGFVLQDIWIQNTAGPEKHQAVALRVSADQSVINRCRIDAYQDTLYTHNYRQFYRDCFIIGTIDFIFGNGAVVLQNCHIISRKPMANQKNMVTAQGRIDPNQNTGISIQNCDIVASSDLESEQ-NKFPTYLGRPWKEYSRTVVMQSNIGGHIDPTGWAEWDKEFALTTLYYGEYANRGLGAGVSKRVNWPGYHVITDPNEAKQFTVAELIQGGAWLGSTGVSFT 547          

Query:  238 RLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNG--------------------QIPSWVKTKDRKLLQAD--GVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYREN-VEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPS 1518
            R+ +A  DCL+LLD S D L+ SLS      G     G   +D+ TWLSAAL NQDTCS GF+G N  V+  ++  L  +T LV   L  +  ++N    +G                      P W+  +DRKLL      +  D IV+ DG G    +++A+  AP+YS RR VIY++ G Y EN +++ +KKWNLM IGDG   TIISG +S  +  TTF +A+FA +G GFIARD+TFEN AGP KHQAVALR  +D +V YRCNI GYQDTLY H+ RQF+R+C I GTVDFIFG+A VVFQNC I A+K +  QKN+ITAQ RKDPN+ TGISI  C I A SDL      S PT+LGRPWKLYSRTV M S++ + + P GWLEWN  FAL++L+YGEYMNYGPG  +G RVKWPGY+V   + +   + + +F  G  +L S
Sbjct:  148 RVRSAFDDCLELLDDSIDALSRSLSTVAPSHGGGTGGGS-PADVVTWLSAALTNQDTCSEGFDGVNGAVKNQMTGRLKDLTELVSNCLA-IFSSANGDDFSGVPVQNKRRLLTENEDISYEENFPRWLGRRDRKLLDVPVPAIHADIIVSGDGNGTCKTISEAIKKAPEYSTRRTVIYVRAGRYEENNLKVGRKKWNLMFIGDGKGKTIISGGKSVFNNLTTFHTASFAATGAGFIARDMTFENWAGPAKHQAVALRVGADHAVVYRCNIIGYQDTLYVHSNRQFFRECDIYGTVDFIFGNAAVVFQNCSIYARKPMAFQKNTITAQNRKDPNQNTGISIHACRILATSDLTPLK-GSFPTFLGRPWKLYSRTVYMLSYIGDHVHPRGWLEWNTTFALDTLYYGEYMNYGPGGAVGQRVKWPGYRVVTSTIEL--FKIMEFSTGLYFLSS 592          

Query:  250 AISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFE--GTNSIVQGLISAGLGQV---TSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYS-MRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            A +DCL L + +  ELN ++         +++T     D +TWLS AL N +TC  GF+  G +  V  L+S  + ++   T  +++  +   P + + G     PSWVK  DRKLLQ    S + +VAQDG+GN   +  A+ AA   S  RR+VI IK G YREN++I KK  N+M++GDG+  TII+G+RS   G+TTF SAT AV+G GFIAR ITF NTAGP+ HQAVALRS SDLSVFYRC   GYQDTLY H+ RQFY++C I GTVDFIFG+A V+ QNC I A++ +  QKN +TAQGR DPN+ TGISI    + A SDL    ++S  TYLGRPWK YSRTV +Q++L +++ P GWLEW+G+FALN+L+YGEY N GPGA    RVKW GY+V   ST+A  +TVA FI G  WLP+TGV +
Sbjct:   94 AWADCLKLYEDTIAELNHTI---------DSNTKCTQFDAQTWLSTALTNLETCKAGFKDLGVSDFVLPLMSNNVSKLIRNTLALKDNASSTLPQTYKDG----FPSWVKAGDRKLLQTSSPSPNLVVAQDGSGNHRTIKAALDAAAKRSGSRRFVIRIKSGVYRENLDIGKKLKNIMLVGDGLRNTIITGSRSVGGGFTTFNSATVAVTGEGFIARGITFRNTAGPQNHQAVALRSGSDLSVFYRCGFEGYQDTLYVHSQRQFYKECYIYGTVDFIFGNAAVILQNCMIYARRPMDKQKNVVTAQGRTDPNQNTGISIHNSRVMASSDLRPV-LSSFKTYLGRPWKEYSRTVFLQTYLDSLVDPAGWLEWDGNFALNTLYYGEYRNSGPGASTRGRVKWRGYRVITSSTEASRFTVANFIAGRSWLPATGVPF 513          

Query:  163 LKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGT--NSIVQGLISAGLGQVTSLVQELLTQVHP---NSNQQGPNGQIPSWVKTKDRKLLQA--DGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            +++TI+  + + S ++       D R   A+ DC++L++ S   +  ++ A +        T K  ++  TWLS+ L N DTC +G  G   +++   L    L   TSL   +L  + P   N++        PSW+ + DRKLL A    ++ D  VA+DG+G +  V +AV +APD    RYVIY+K+GTY+ENVE+ KKK N+M++GDGMD+TII+G+ + VDG TTF SAT A  G GFIA+DI F+NTAGPEKHQAVALR  +D SV  RC I  YQDTLYTH++RQFYRD  I+GTVDFIFG+A VV QNC+++ +K +  QKN +TAQGR DPN+ TG SIQ C+I A SDL     +S  ++LGRPWK YSRTV+MQS + ++I P GW  W+G+FAL +L+YGEY+N G GAG   RV W GY V   + +AK +TVA+ I+G +WL STGV YT
Sbjct:   98 IQNTIEKAEVIHSRIN-------DAREQAALGDCVELMEISKYRIKDTIVALERV------TSKSHANALTWLSSVLTNHDTCLDGLNGPARSTMEPDLNDLILRARTSLA--ILAAISPSKENNDIFSLKEDFPSWLPSMDRKLLVALPKDINADVTVAKDGSGKYKTVKEAVASAPDNGKTRYVIYVKKGTYKENVEVGKKKKNVMLVGDGMDSTIITGSLNVVDGSTTFNSATVAAVGDGFIAQDIWFQNTAGPEKHQAVALRVGADQSVINRCRIDAYQDTLYTHSLRQFYRDSYITGTVDFIFGNAAVVLQNCKLVPRKPMSGQKNMVTAQGRTDPNQNTGTSIQKCDIIASSDLTPVK-SSFKSFLGRPWKEYSRTVVMQSNIGDLIDPAGWSAWDGEFALKTLYYGEYLNQGAGAGTSKRVNWAGYHVITSANEAKKFTVAELIQGGVWLKSTGVSYT 546          

Query:  337 NNSTGKLSS--DLRTWLSAALVNQDTCSNGFE--GTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDA--IVAQDGTGNFTNVTDAVLAAPDYS-MRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            N +TG   +  D +TWLS AL N +TC  GF   G    +  ++S     V+ L+   L       ++   NG  PSWV+  DRKLLQ+   +  A  +VAQDG+GN   + +A++AA   S   RYVIY+K GTY ENVE+ +K  N+M++GDG+  TI++G++S   G TTF+SATFAV G  FIARD+TF NTAG + HQAVALRS SDLSVFY+C+  GYQDTLY H+ RQFYR+C I GTVDFIFG+A VVFQNC I A+   PN+ N+ITAQGR DPN+ TGISI  C +TA SDL++   +S  TYLGRPW+ YSRTV M++ L ++I   GW+ W+G+FAL++L+YGEYMN GPG+   +RV W GY V   ++ A  +TVA FI GN WLP+T V +TA
Sbjct:  110 NKTTGSKCTKYDAQTWLSTALTNLETCRTGFAEFGMTDYILPMMS---NNVSKLISNTLAINKAPYSEPSFNGGFPSWVRPGDRKLLQSSSPASQANIVVAQDGSGNVKTIKEAIVAASKRSGSGRYVIYVKAGTYNENVEVGQKVKNVMVVGDGIGKTIVTGSKSVGGGTTTFKSATFAVVGDNFIARDMTFRNTAGAKNHQAVALRSGSDLSVFYKCSFEGYQDTLYVHSQRQFYRECNIYGTVDFIFGNAAVVFQNCNIYARNP-PNKTNTITAQGRTDPNQNTGISIHNCKVTAASDLKSVQ-SSVKTYLGRPWQKYSRTVFMKTDLDSLINSAGWMPWSGNFALDTLYYGEYMNTGPGSSTANRVNWKGYHVITSASVASQFTVASFISGNNWLPATNVPFTA 512          

Query:  139 SATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLT---QVH-----------PNSNQQGPNGQIPSWVKTKDRKLLQAD---GVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEF 1545
            S +    +L  T++  +    I+++F +    +R + AI DC +LLD+S  EL WSL      +G + +      +L+ WLSAAL NQDTC  GFEGT+   +  +   + QVT L+  +LT   Q+H           P +N+  P    P+W+  +D++L++++   GV+  A+VA DG+G +  +T+AV  AP+YS  RYVIY+K+G YREN+E+KK K N+M +GDG+  TII+GNRSF+ GWTTFR+AT AVSGRGFIAR++T  NTA P+ HQAVALR DSD S F++C++ GYQDTLY H++RQF+R+C I GTVDFIFG+   V QNC+I  +  LP QK +ITAQGRK P++ TG +IQ   + A          + PTYLGRPWK YSRTV M +++S +++P GWLEWNGDFAL +L+YGEY NYGPGA +  RVKW GY +  ++  A  +TV +FI+G  WLPSTG+K+TA F
Sbjct:   61 SVSILTAALTHTLNETKNAIQIITKFNSLPRSYRESVAIEDCKELLDYSFSELAWSLGEMIKIRGGDTNV-HYEGNLKAWLSAALSNQDTCLEGFEGTDRRFESFVRGSVKQVTQLIGNVLTLYTQLHSLPSKPPRHHGPPTNKSSPGDYFPAWMSEEDQELVKSNPKSGVN-HAVVAADGSGQYRTITEAVNEAPNYSPSRYVIYVKKGIYRENIEMKKNKTNIMFVGDGIGQTIITGNRSFMQGWTTFRTATVAVSGRGFIARNLTIRNTAAPQNHQAVALRVDSDQSAFFQCSVEGYQDTLYAHSLRQFFRECTIYGTVDFIFGNGAAVLQNCKIYTRVPLPQQKITITAQGRKSPHQSTGFAIQDSFVLA----------TQPTYLGRPWKKYSRTVYMNTYMSRLVQPRGWLEWNGDFALGTLWYGEYKNYGPGAAMSGRVKWRGYHILRDAAAASFFTVGRFIDGMAWLPSTGIKFTAGF 534          

Query:  139 SATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELL---TQVH----------PNSNQQGPNGQIPSWVKTKDRKLLQADGVS--VDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            S +    +L+ T++  +    ++++F +    +R + AI DC +LLD+S  EL WSL      +G + +      DL++WLSAAL NQDTC  GFEGT+  ++  +   L QVT L+  +L   TQ++          P  N+       P+W+   D+ L++++  S    A+VA DG+G +  +T+AV  AP+YS  RYVIY+K+G Y+EN+++KKKK N+M +GDG+  TI++GNR+F+ GWTTFR+AT AVSG+GFIA+++T  NTAGP+ HQ VALR DSD S F+RC+I G QDTLY H++RQFYR+C I GT+DFIFG+   V QNC+I  +  LP QK +ITAQGRK+P++ TG +IQ   + A          + PTYLGRPWK YSRTV M +++S +++P GWLEW GDFAL++L+YGEY NYGPGAGL  RVKWPGY +  ++  A  +TV +FI+G  WLPSTGVK+TA
Sbjct:   61 SVSIITAALRHTLNETKNAIQMITKFNSLSISYRESVAIEDCKELLDYSVSELAWSLGEMIKIRGGDTNV-HYEGDLKSWLSAALSNQDTCLEGFEGTDRRLESFVRGSLKQVTQLIGNVLALYTQLYSLPSPPRDHGPPMNKSSSGDDFPAWMSEDDQALVKSNPKSGAKHAVVAADGSGQYRTITEAVNEAPNYSPSRYVIYVKKGIYKENIDLKKKKTNIMFVGDGIGQTIVTGNRNFMQGWTTFRTATVAVSGKGFIAKEMTIRNTAGPQNHQGVALRVDSDQSAFFRCSIEGNQDTLYAHSLRQFYRECSIYGTIDFIFGNGAAVLQNCKIYTRVPLPLQKVTITAQGRKNPHQNTGFTIQDSFVLA----------TQPTYLGRPWKEYSRTVYMNTYMSGLVQPRGWLEWYGDFALSTLWYGEYRNYGPGAGLAGRVKWPGYHILKDAAAASFFTVGRFIDGRAWLPSTGVKFTA 531          

Query:  250 AISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQ-----GLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVS----VDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYT 1536
            AI DC++L+D + D +  S+ A Q     N  +     D+  WLS+ L N  TC +G EG    +       L+S     + ++V  +  +   N  ++  +G  P+WV +KDR+LL    ++     +A+VA+DG+GN+  V +AV AAPD S  RY I++K+GTY+ENVE+ KKK NLM  GDGM  TII+G+ + VDG TTF SAT A  G GFIA+DI F+NTAG  KHQAVALR  +D SV  RC I  YQDTLY H+ RQFYRD  I+GTVDFIFG+A VVFQNC+I+A+K +  Q N +TAQGR DPN+ TG SIQ C++ A SDLE     +  +YLGRPWK YSRTV+MQS + + I P GW  W+GDFAL +L+YGEY N GPGAG   RVKW GY V     +A+ +TVA  I+G  WL STGV YT
Sbjct:  249 AIVDCVELMDVTKDRVMDSMVALQKFGAHNYYS---LEDVHGWLSSVLTNHVTCLDGLEGPARTMMEPWLNDLVSRSXASL-AIVVAISDRSKSNPIKERLDGIFPTWVTSKDRRLLLDSNLAKESNANAVVAKDGSGNYKTVKEAVAAAPDNSKTRYXIHVKKGTYKENVEVGKKKKNLMXTGDGMHNTIITGSLNVVDGATTFNSATLAAVGDGFIAQDIWFQNTAGAAKHQAVALRVGADRSVINRCRIDAYQDTLYAHSNRQFYRDSXITGTVDFIFGNAAVVFQNCKIVARKPMTGQNNMVTAQGRIDPNQNTGTSIQKCDVVASSDLEPVK-GTIRSYLGRPWKEYSRTVVMQSKIGDHIDPAGWSIWSGDFALKTLYYGEYANSGPGAGTSKRVKWAGYHVITSPKKAQPFTVANLIQGGSWLKSTGVTYT 681          

Query:  109 DDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAI-SDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELL----TQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            +++  Q + V    F  SL+ T++AVQ VAS +S            N I S C  LL  + + LNWSLS   + KG       + S +RTWL+ +   + TC   F+     +   +S  L   T L+ E++     Q H   N   P   +      +D K  +   V+V    +QDG+GNF  + DA+ AAP +S +R+VI+IK+G Y+E V+I   K NL++IG+GMD T ISGNR    GW T  SATFAV   GFIA  + FENTAGP K+QAV+L S  D SVFYRC + GYQDTL     R FYR+C ISGT+DFIFG  T VFQNC+ILA+K L   +N++TA GR    +P+G S QFCN+  DSDL   +V S+PTYLGRPW  YSRT+ MQS++SNVI PEGWL+WNG   L +L+Y EYMN G GA    RVKWPGY V  ++++AK +TV +FI+G+ WLPSTGV Y
Sbjct:   29 NNVDPQLIDVPLPVFKNSLEKTMEAVQNVASAMSHMHVGEDAKNSTNMIISYCEGLLGETVEVLNWSLSTIHDLKGD------VVSHMRTWLNTSHYREMTCMEAFKNG---IDSRVSESLKHATRLIDEVIGMIQVQQHDYQNVDQPL-LLSGGTNFEDAKFSKTPNVTV----SQDGSGNFNRIMDAIAAAPSHSQQRFVIFIKKGIYKEYVKIDPTKTNLVLIGEGMDVTTISGNRCNASGWQTVDSATFAVRAEGFIAMYVGFENTAGPNKYQAVSLSSYGDQSVFYRCKMSGYQDTLLVPAGRXFYRECTISGTIDFIFGYGTAVFQNCKILARKNLEGAQNTLTAHGR-FAADPSGFSFQFCNVERDSDL-GGNVASSPTYLGRPWGKYSRTIFMQSYMSNVIVPEGWLDWNGFGGLGTLYYAEYMNKG-GASTVGRVKWPGYHVIAKASEAKLFTVTKFIDGDSWLPSTGVPY 491          

Query:  109 DDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAI-SDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELL----TQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            +++  Q + V    F  SL+ T++AVQ VAS +S            N I S C  LL  + + LNWSLS   + KG       + S +RTWL+ +   + TC   F+     +   +S  L   T L+ E++     Q H   N   P   +      +D K  +   V+V    +QDG+GNF  + DA+ AAP +S +R+VI+IK+G Y+E V+I   K NL++IG+GMD T ISGNR    GW T  SATFAV   GFIA  + FENTAGP K+QAV+L S  D SVFYRC + GYQDTL     R FYR+C ISGT+DFIFG  T VFQNC+ILA+K L   +N++TA GR    +P+G S QFCN+  DSDL   +V S+PTYLGRPW  YSRT+ MQS++SNVI PEGWL+WNG   L +L+Y EYMN G GA    RVKWPGY V  ++++AK +TV +FI+G+ WLPSTGV Y
Sbjct:   29 NNVDPQLIDVPLPVFKNSLEKTMEAVQNVASAMSHMHVGEDAKNSTNMIISYCEGLLGETVEVLNWSLSTIHDLKGD------VVSHMRTWLNTSHYREMTCMEAFKNG---IDSRVSESLKHATRLIDEVIGMIQVQQHDYQNVDQPL-LLSGGTNFEDAKFSKTPNVTV----SQDGSGNFNRIMDAIAAAPSHSQQRFVIFIKKGIYKEYVKIDPTKTNLVLIGEGMDVTTISGNRCNASGWQTVDSATFAVRAEGFIAMYVGFENTAGPNKYQAVSLSSYGDQSVFYRCKMSGYQDTLLVPAGRXFYRECTISGTIDFIFGYGTAVFQNCKILARKNLEGAQNTLTAHGR-FAADPSGFSFQFCNVERDSDL-GGNVASSPTYLGRPWGKYSRTIFMQSYMSNVIVPEGWLDWNGFGGLGTLYYAEYMNKG-GASTVGRVKWPGYHVIAKASEAKLFTVTKFIDGDSWLPSTGVPY 491          

Query:  175 IDAVQQVASILSQFANAFGDFRLAN-AISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKD--RKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASV-NSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            +D V  VAS +S       D + A  AI  C DLL  +A  LNWSLS   + K        + S +  W + +L    TC   FEGTNSI+ G    GL QVT+ +  LL  +H +             ++T    R  LQ        +V+ DG+G+F  ++DA+ AAPD+S + + I++KRG Y E V I  KK NL+++G+GMD TIISGNRS   GW T  SATF V   GFIA +I F NTAGP K QAVALRS  D S F++C+I GYQDTL  H  RQFYR CKISGTVDFIFG  T VFQ C I++K+     +N ITA GR + N+PTG S QFCNI  D+     SV N TPTYLGRPW   SRTV MQS L  VIRPEGW EW+GDF L +L+YGEYMN G G+ L  RVKWPGY V  + + A  +TVA+FI GN WLPSTG+ Y
Sbjct:    1 MDVVLNVASTMSHMHVEKHDGQNAKIAIPYCADLLGSTAQVLNWSLSTIHDLKDD------VISHMGAWSNTSLSRHKTCMEAFEGTNSILAG----GLKQVTTSIHGLLGMLHAHQT-----ADFVGSIRTSKHIRPWLQRPNF----VVSHDGSGDFKLISDAITAAPDHSRQYFXIFVKRGVYYEYVNIGAKKSNLVLVGEGMDNTIISGNRSNGTGWGTSDSATFTVKADGFIAVNIGFVNTAGPYKMQAVALRSQGDRSAFFQCSISGYQDTLLVHDGRQFYRMCKISGTVDFIFGYGTAVFQKCTIISKQNGKGGRNEITAHGRFNQNDPTGFSFQFCNIVHDNSHGTVSVENQTPTYLGRPWGNCSRTVFMQSQLDAVIRPEGWHEWSGDFGLKTLYYGEYMNEGLGSNLSHRVKWPGYHVITDPSVADQFTVAKFIGGNSWLPSTGIPY 438          

Query:  250 AISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEG--TNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAV-LAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLW 1509
            A +DC+ L + +   LN ++  +         T     D +TWLS AL N DTC  GF     +  V  L+S  + ++ S    L    + +          PSWV   DRKLLQ+   + D +VAQDG+GN+  +  A+  AA     +R+VI++KRG Y+EN+EIK K   + ++GDG+  TII+G+RS V G TTF+SAT AV+G GFIAR ITF NTAGPE HQAVALRS +DLSVFYRC   GYQDTLYTH+ RQFYR+C + GTVDFIFG+A VVFQNC I A+K +  Q+N+ITAQGR DPN+ TGISI    + A  DLE +SV S  T+LGRPWK YSRTV MQSFL  ++ P GWL+W+GDFAL +L+YGEY N GPGA    RVKW GY++   S++A  +TV  FI G+ W
Sbjct:   51 AWADCMSLYEETIKLLNQTIDPA---------TKSTDYDTQTWLSTALTNLDTCRAGFVELEVSDFVFPLMSNNVSKLISNTLSLWNSSNVSPVTXMYTEGYPSWVSPGDRKLLQSTPTA-DVVVAQDGSGNYKTIKAALDAAAARGGSKRFVIHVKRGVYKENLEIKLKX--IYLLGDGLRYTIITGSRSVVGGSTTFKSATVAVTGEGFIARGITFRNTAGPENHQAVALRSGADLSVFYRCGFEGYQDTLYTHSQRQFYRECYVYGTVDFIFGNAAVVFQNCMIYARKPMSGQQNTITAQGRTDPNQNTGISIHDSRVMAALDLE-SSVGSVKTFLGRPWKEYSRTVFMQSFLDTLVDPAGWLQWSGDFALKTLYYGEYKNIGPGAPTTGRVKWGGYRIITSSSEASKFTVDNFIAGSSW 460          

Query:  160 SLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTN---SIVQGL-----ISAGLGQVTS------LVQELLTQVHPNSNQQGPNGQI------PSWVKTKDRKLLQA--DGVSVDAIVAQDGTGNFTNVTDAVLAAPDY---SMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTV 1482
            S+   I+A Q V S+     +A    R   A +DCL+L + + D+LN S+ ++             + D+ TWLSA+L NQ TC NGF+  N   S +Q       +S  L ++ S       V    + +H +   +G   ++      P WV   DRKLLQ+   G + D +VAQDG+GN+ ++++AV AA      + +R+VI++K G YREN+EIKK   N+M IGDG+DATI++GN +  DG TT+RSATF   G GFIA+D+TFENTAGP+K+QAVALRS SD SVFYRC+ +GYQDTLY ++ RQFYR+C I GT+DFI GDATVV QNC I A+K + NQ N++TAQ R DPNE TGI I    ITA  DL      S  TYLGRPWK YSRTVIM+S L  +I P GW  W G FA ++L+YGEYMN G GAG G RV WPGY V + + +A   T+
Sbjct:   65 SMDQAIEAHQLVLSLNLNSLDA-DHTRAKGAWNDCLELYEDTVDKLNRSIGSTN------------ALDVNTWLSASLTNQQTCQNGFKNLNIPSSHLQSFPNYVTLSTNLSKLLSNSLSIHKVSTSSSALHFSKQVRGRRRRLLSDDGFPEWVSAADRKLLQSISSGPNADMVVAQDGSGNYKSISEAVDAAYKLQGGATKRFVIHVKAGVYRENIEIKKTMKNIMFIGDGIDATIVTGNENVQDGSTTYRSATFGAXGDGFIAQDMTFENTAGPQKYQAVALRSGSDHSVFYRCSFKGYQDTLYVYSQRQFYRECDIYGTIDFICGDATVVLQNCNIYARKPMSNQVNTVTAQSRTDPNENTGIVIHNSRITAAQDLRPVQ-GSFKTYLGRPWKKYSRTVIMKSNLDGLINPAGWFPWIGSFAPSTLYYGEYMNSGAGAGTGGRVNWPGYHVISSAGEAGKLTI 516          

Query:  160 SLKDTIDAVQQVASILSQF-----------ANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKY 1533
            SL  T++ VQ VAS +S             A    D  L  AI  C  +L  + + +NWSLS       +    G + S  RT L+A L  Q TC   F+GT      +I+    QV S  Q+LL  +     +      +  W KT +              V+QDG+GNF  +T+A+  AP ++   +VI++KRG Y+ENV I   K NL++IG+GMD T ISG+RSF  GW TF SATF     GFIA DI FENTAGPE +QAVAL S  D +VFYRC I GYQDTL  H  RQF+R+C+ISG++DFIFG    VFQ C +  KK +P   N++TA GR  P +PTG S QFC I+ADSD+ AA       YLGRPW  YSRTV MQS++SNVI+P+GW+EW G  ALN+L+YGEY N GPGA L SRV WPGY V     +A  +T A+FIEG+ WL ST V +
Sbjct:   41 SLDSTMELVQNVASAMSNIHMYXDPDXDADAXEDDDRNLKIAIXHCGYVLGSTYEAMNWSLSTIHQDYKQYKGKGDVISHARTRLNANLERQKTCVEAFDGTK---YSMITQSFKQVRSSTQDLLKMLQAKPGRIEAKAGLEFW-KTPN------------VTVSQDGSGNFRTITEALAVAPSHNQNYFVIFVKRGVYKENVNIDSSKCNLVLIGEGMDVTTISGSRSFRSGWETFYSATFD----GFIAMDIGFENTAGPENYQAVALLSGGDRAVFYRCKISGYQDTLLVHAGRQFFRECQISGSLDFIFGYGAAVFQKCLLTVKKTIPGVINTVTAHGRYAPXDPTGFSFQFCTISADSDVAAA-------YLGRPWGKYSRTVFMQSYISNVIQPQGWIEWKGKSALNTLYYGEYTNNGPGARLSSRVNWPGYHVIENPAEADEFTTAKFIEGDSWLTSTNVPF 482          

Query:  130 LKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQ----IPSWVKTKDRKLLQADGVSVDA----IVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEF 1545
            L+V+ +E AG L D      Q  +I+          +   A+ DC +L   +   L  S+S  Q Q G      K  +D R +LSAAL N++TC  G +  +  ++  +   L      V   L+ +      +G   +    IP W+  +DR++L++ G   D      VA DG+GNFT ++DA++ AP+ S  R +IY+K G Y ENVEI   K N++++GDG D T I+GNRS VDGWTTFRSAT AVS  GF+ARDIT  NTAGP KHQAVALR ++DL+  Y+C I GYQDTLY H+ RQFYR+C I GT+D+IFG+A VVFQ C I++K  +P Q   +TAQ R+ P++ TGIS+Q C+I A  +L + S +   +YLGRPWK YS TV+++S++ + I P GW  W+GD  LN+L+YGEY NYGPGAG  +RV W G+ V  +   A N+TV +FI G+ WL +   +   EF
Sbjct:   76 LQVAISE-AGKLTDLFYKAGQYPNIVE---------KQKGAVQDCKELHQITLSSLQRSVS--QVQAGN----AKKLNDARAYLSAALTNKNTCMEGLDSASGPMKPTLVNSLTSTYKYVSNSLSAISKQGTNKGRTNRRLMSIPRWLSRRDRRILESSGDEYDPREVLTVAADGSGNFTTISDAIIFAPNNSYDRTIIYVKEGVYEENVEIPSYKTNIVLLGDGSDITFITGNRSVVDGWTTFRSATVAVSAEGFLARDITIRNTAGPIKHQAVALRINADLAAIYKCTIDGYQDTLYVHSFRQFYRECDIFGTIDYIFGNAAVVFQACNIVSKMPMPGQFTVVTAQSRETPDQNTGISVQNCSIIATDELYSNS-SIVKSYLGRPWKNYSTTVVLESYIDDFIDPTGWKNWSGDLGLNTLYYGEYGNYGPGAGTENRVNWKGHHVM-DYYDASNFTVQEFIAGDEWLQARINQLKIEF 537          

Query:    1 MASHNPLPAGKQXXXXXXXXXXXXXXXXXXXXXXXTDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            MASHNPLPAGKQ                       TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTY+ENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV
Sbjct:    6 MASHNPLPAGKQLLLLVLLCAFFSSSFIPFASCSITDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYKENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 522          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFG 1548
            T+D++++CLKV A+EFAGSL+DTI AVQQVASILSQFA AFGDF L+NAISDCLDLLDF+ADELNWSLSASQN +GK+NSTGKLSSDLRTWLSAALVNQDTCS+GFEGTNSIV+GL++ GL QVTSLVQ LLTQV PN++  GPNG+IPSWVK +DRKLLQA GV+VDA+VAQDGTGNFTNVTDAVLAAPD SM RYVIYIK GTY+ENVEIKKKKWNLMMIGDGMDATIISG+R+FVDGWTTFRSATFAVSGRGFIARD+TFENTAGPEKHQAVALRSDSDLSVFYRC IRGYQDTLY H MRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNS+TAQGRKDPNEPTGISIQFCNITAD+DL    VNST TYLGRPWKLYSRTVIMQSFLSN IRPEGWLEWN DFAL++L YGEY+NYGPGAGL SRVKWPGY+VFNESTQ +NYTVAQFIEG+LWLP+TGVKYTA  G
Sbjct:   29 TNDIRSECLKVPASEFAGSLRDTIGAVQQVASILSQFATAFGDFHLSNAISDCLDLLDFTADELNWSLSASQNPEGKDNSTGKLSSDLRTWLSAALVNQDTCSDGFEGTNSIVKGLVTTGLNQVTSLVQGLLTQVQPNTDHHGPNGEIPSWVKAEDRKLLQAGGVNVDAVVAQDGTGNFTNVTDAVLAAPDESMTRYVIYIKGGTYKENVEIKKKKWNLMMIGDGMDATIISGSRNFVDGWTTFRSATFAVSGRGFIARDLTFENTAGPEKHQAVALRSDSDLSVFYRCQIRGYQDTLYAHAMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSVTAQGRKDPNEPTGISIQFCNITADADL-LPFVNSTSTYLGRPWKLYSRTVIMQSFLSNAIRPEGWLEWNADFALSTLSYGEYINYGPGAGLESRVKWPGYRVFNESTQVQNYTVAQFIEGDLWLPTTGVKYTAGLG 508          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQ-QGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVN-STPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            ++ +Q++CLKV  +EF GS+ +TI+ +QQV SILS  A  FGDFRL+NA+ DCL+L+D S D+L+W+LSA+QN+ GK+NSTG LSSDLRTWLSA LVNQDTC+ G +GTNSIV+ L+S  L Q+TSLV ELL QVHP S+Q +  NGQ P+W K +DRKLLQA+GV VD +VAQDGTGNFTN+T A+L+APDYS++RYVIY+K+G Y+E VEIKKKKWN+MMIGDGMDAT+ISGN +FVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKH AVALRSDSDLS FYRC  RGYQDTLYTH+MRQFYRDCKISGTVDFIFGD TV+FQNCQILA+K LPNQKNSITA GRK  +EPTG S QFCNI+A  DL A  VN STPTYLGRPWK YSRT+IMQSF+SN+I+P GWLEWNGD  L +LFYGE+MNYGPGAGLGSRV WPGYQ FN+S QAKNYTVA+FIEGNLWLPSTGVKYT+ FGV
Sbjct:   31 SNTIQSECLKVPNSEFGGSIINTINVLQQVVSILSDVAKGFGDFRLSNAVDDCLELMDDSTDQLSWTLSATQNKNGKHNSTGNLSSDLRTWLSATLVNQDTCNEGLDGTNSIVKSLVSGSLNQITSLVLELLGQVHPTSDQHESSNGQTPAWFKAEDRKLLQANGVPVDVVVAQDGTGNFTNITAAILSAPDYSLKRYVIYVKKGLYKEYVEIKKKKWNIMMIGDGMDATVISGNHNFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHMAVALRSDSDLSAFYRCEFRGYQDTLYTHSMRQFYRDCKISGTVDFIFGDGTVMFQNCQILARKALPNQKNSITAHGRKYKDEPTGFSFQFCNISAHPDLLATPVNSSTPTYLGRPWKEYSRTIIMQSFMSNMIKPAGWLEWNGDMFLKTLFYGEHMNYGPGAGLGSRVTWPGYQKFNQSGQAKNYTVAEFIEGNLWLPSTGVKYTSGFGV 514          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQ---QGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDL--EAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            T+ + ++ LKV+ +EF G+++  +D +Q+V SILS+F + FGD RL+NA+SDCLDLLD S+DEL+WS+SA+Q+ KGK+NSTG  SSDLRTWLSAAL NQDTC +GF+GTN +V+GL+S G+GQV SL+Q+LLTQV P S+      P GQ PSWVKT +RKLLQA+ VS DA+VA DGTGN+T V DAVLAAP+YSM+RYVI+IKRG Y ENVEIKKKKWNLMM+GDGMDATIISGNRSF+DGWTTFRSATFAVSGRGFIARDITF+NTAGPEKHQAVALRSDSDLSVF+RC I GYQD+LYTHTMRQFYR+CKISGTVDFIFGDAT +FQNC I AKKGLPNQKN+ITA GRK+P+EPTG SIQFCNI+AD DL     S NST TYLGRPWK YSRT+ MQS++S+V+RPEGWLEWNGDFAL++L+Y EYMNYGPGAG+ +RVKW GY V N+S+QA N+TV+QFIEGNLWLPSTGV +TA  GV
Sbjct:   41 TNTVGSELLKVAPSEFEGTVRTVVDVLQEVTSILSEFGSGFGDSRLSNAVSDCLDLLDMSSDELDWSVSATQSPKGKHNSTGNTSSDLRTWLSAALANQDTCIDGFDGTNGMVKGLVSTGIGQVMSLLQQLLTQVKPVSDHFSFSSPQGQYPSWVKTGERKLLQANVVSFDAVVAADGTGNYTKVMDAVLAAPNYSMQRYVIHIKRGVYYENVEIKKKKWNLMMVGDGMDATIISGNRSFIDGWTTFRSATFAVSGRGFIARDITFQNTAGPEKHQAVALRSDSDLSVFFRCGIFGYQDSLYTHTMRQFYRECKISGTVDFIFGDATAIFQNCHISAKKGLPNQKNTITAHGRKNPDEPTGFSIQFCNISADYDLVNSVNSFNSTHTYLGRPWKPYSRTIFMQSYISDVLRPEGWLEWNGDFALDTLYYAEYMNYGPGAGVANRVKWQGYHVMNDSSQASNFTVSQFIEGNLWLPSTGVTFTAGLGV 527          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQ---QGPNGQIPSWVKTKDRKLLQA-DGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAA----SVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFG 1548
            T+ + ++ LKV+ +EFAG+++  +D +Q + SILS+F + FGD RL+NA+SDCL+LLD S+DEL+WS+SA+Q+ KGK+NSTG  SSDLRTWLSAAL NQDTC +GF+GTN IV+GL+S GLGQV SL+Q+LLTQV+P S+      P G  P WVK  +RKLLQA +GVS DA+VA DGTGNFT V DAVLAAP+YSM+RYVI+IKRG Y ENVEIKKKKWNLMM+GDGMD T+ISGNRSF+DGWTTFRSATFAVSGRGF+ARDITF+NTAGPEKHQAVALRSDSDLSVF+RC I GYQD+LYTHTMRQFYR+CKISGTVDFIFGDAT +FQNC I AKKGLPNQKN+ITA GRK+P+EPTG SIQFCNI+AD DL  +    S NS  TYLGRPWK YSRTV MQS++S+V+RPEGWLEWNGDFAL++L+Y EYMNYGPGAG+ +RVKWPGY V N+S+QA N+TV+QFIEGNLWLPSTGV +TA  G
Sbjct:   38 TNTVGSELLKVAPSEFAGTVRTVVDVLQDITSILSEFGSGFGDSRLSNAVSDCLELLDMSSDELDWSVSATQSPKGKHNSTGNTSSDLRTWLSAALANQDTCMDGFDGTNGIVKGLVSTGLGQVMSLLQQLLTQVNPVSDHYTFSSPQGHFPPWVKPGERKLLQAANGVSFDAVVAADGTGNFTKVMDAVLAAPNYSMQRYVIHIKRGVYNENVEIKKKKWNLMMVGDGMDNTVISGNRSFIDGWTTFRSATFAVSGRGFVARDITFQNTAGPEKHQAVALRSDSDLSVFFRCGIFGYQDSLYTHTMRQFYRECKISGTVDFIFGDATAIFQNCHISAKKGLPNQKNTITAHGRKNPDEPTGFSIQFCNISADYDLVNSINNNSNNSIGTYLGRPWKPYSRTVFMQSYISDVLRPEGWLEWNGDFALDTLYYAEYMNYGPGAGVANRVKWPGYHVMNDSSQASNFTVSQFIEGNLWLPSTGVTFTAGLG 526          

Query:  115 LQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHP----------NSNQQGPNG-------QIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            L+T+CLKV ATEF GSLK TIDA+++  S++SQF   F DFRL+NAISDCLDLLD SADEL+W++SASQN   K+NSTG LSSDLRTWLSAA+VNQ TC +GFEGTNS+V+ ++S  L Q+TSLV+ LL  VHP          N +Q+G  G       + P W K +DR+LLQ +GV+ + +VA DG+GNFT + DAV  APD SM RYVIYIK+G Y+ENVEIKKKKWNL+MIGDGMD T+ISGNRSF+DGWTT RSATFAVSGRGFIARDITFENTAGP+KHQAVALRSDSDLSVF+RC I+GYQD+LYTHTMRQFYR+CKI+GTVDFIFGD  V+FQNCQILAK+GLP+QKN+ITAQGRKDPN+PTG SIQFCNI+AD+DL   SVNSTPTYLGRPWKLYSRT+IMQS++S+ IRP+GWLEWN DFAL++L+Y EYMN GPGA L  RVKWPGY V N S QA N+TVAQFIEG+LWLPSTGVKYT+ FGV
Sbjct:   31 LETECLKVPATEFIGSLKTTIDAIRKATSVVSQFGGFFHDFRLSNAISDCLDLLDSSADELSWTMSASQNPNAKDNSTGDLSSDLRTWLSAAMVNQQTCIDGFEGTNSMVKTVVSGSLNQITSLVRNLLIMVHPGPNSKSNGTRNGSQKGGGGGGHPGQSRFPVWFKREDRRLLQINGVTANVVVAADGSGNFTRIMDAVETAPDKSMNRYVIYIKKGLYKENVEIKKKKWNLVMIGDGMDVTVISGNRSFIDGWTTLRSATFAVSGRGFIARDITFENTAGPQKHQAVALRSDSDLSVFFRCAIKGYQDSLYTHTMRQFYRECKITGTVDFIFGDGAVLFQNCQILAKQGLPSQKNTITAQGRKDPNQPTGFSIQFCNISADTDL-LPSVNSTPTYLGRPWKLYSRTIIMQSYISDAIRPQGWLEWNQDFALDTLYYAEYMNNGPGASLSERVKWPGYHVLNNSAQAVNFTVAQFIEGDLWLPSTGVKYTSGFGV 525          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQ-----------GPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            TDDLQ  CLKV   +F GSL  T+D ++ V SI+S F N FGD RL NAI+DCLDLLDFSADEL+WS+SASQN  GK+NSTG LSSDLRTWLSAALVNQDTC  GF+GTN+I++GL+S  L Q+TS VQELL  V P++N +           G N + PSWVK +DRKLL  +GV+ + IVA DGTGNFT + DAV AAPDYSM R++IYIK+G Y E V+IKKKKWNLMM+G+GM+ATII+GNR+F+DGWTTFRSATFAVSGRGFIARDITFENTAGP KHQAVALRSDSDLSVF+RC I+ YQD+LYTHTMRQFYR+C++SGTVDFIFGDAT VFQNCQILA+KGLP+QKN++TA GRKDPN+PTG S QFCNI+AD DL    VNS+ TYLGRPWK +SRT+IMQS++SN IRPEGWLEWNG+  L++L+YGEY+NYGPGAG+G RV+WPG+ + N+STQA NYTVAQFI+GNLWLPSTGV+YTA
Sbjct:   29 TDDLQNNCLKVPVNQFVGSLTSTLDIIRDVISIISNFGNVFGDIRLTNAITDCLDLLDFSADELSWSMSASQNPNGKHNSTGDLSSDLRTWLSAALVNQDTCIEGFDGTNNILKGLVSGSLNQITSSVQELLKNVDPHTNSKSSGGGFSGSKSGNNDRFPSWVKHEDRKLLVLNGVTPNVIVAADGTGNFTKIMDAVAAAPDYSMHRHIIYIKKGVYNEYVDIKKKKWNLMMVGEGMNATIITGNRNFIDGWTTFRSATFAVSGRGFIARDITFENTAGPSKHQAVALRSDSDLSVFFRCEIKSYQDSLYTHTMRQFYRECRVSGTVDFIFGDATAVFQNCQILARKGLPDQKNTVTAHGRKDPNQPTGYSFQFCNISADIDL-LPYVNSSYTYLGRPWKNFSRTIIMQSYMSNAIRPEGWLEWNGNVYLDTLYYGEYINYGPGAGVGRRVRWPGFHMLNDSTQANNYTVAQFIQGNLWLPSTGVRYTA 516          

Query:  106 TDDLQTQCLKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQ-----------GPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTA 1539
            TDDLQ  CLKV   +F GSL  T+D ++ V SI+S F N FGD RL NAI+DCLDLLDFSADEL+WS+SASQN  GK+NSTG LSSDLRTWLSAALVNQDTC  GF+GTN+I++GL+S  L Q+TS VQELL  V P++N +           G N + PSWVK +DRKLL  +GV+ + IVA DGTGNFT + DAV AAPDYSM R++IYIK+G Y E V+IKKKKWNLMM+G+GM+ATII+GNR+F+DGWTTFRSATFAVSGRGFIARDITFENTAGP KHQAVALRSDSDLSVF+RC I+ YQD+LYTHTMRQFYR+C++SGTVDFIFGDAT VFQNCQILA+KGLP+QKN++TA GRKDPN+PTG S QFCNI+AD DL    VNS+ TYLGRPWK +SRT+IMQS++SN IRPEGWLEWNG+  L++L+YGEY+NYGPGAG+G RV+WPG+ + N+STQA NYTVAQFI+GNLWLPSTGV+YTA
Sbjct:   37 TDDLQNNCLKVPVNQFVGSLTSTLDIIRDVISIISNFGNVFGDIRLTNAITDCLDLLDFSADELSWSMSASQNPNGKHNSTGDLSSDLRTWLSAALVNQDTCIEGFDGTNNILKGLVSGSLNQITSSVQELLKNVDPHTNSKSSGGGFSGSKSGNNDRFPSWVKHEDRKLLVLNGVTPNVIVAADGTGNFTKIMDAVAAAPDYSMHRHIIYIKKGVYNEYVDIKKKKWNLMMVGEGMNATIITGNRNFIDGWTTFRSATFAVSGRGFIARDITFENTAGPSKHQAVALRSDSDLSVFFRCEIKSYQDSLYTHTMRQFYRECRVSGTVDFIFGDATAVFQNCQILARKGLPDQKNTVTAHGRKDPNQPTGYSFQFCNISADIDL-LPYVNSSYTYLGRPWKNFSRTIIMQSYMSNAIRPEGWLEWNGNVYLDTLYYGEYINYGPGAGVGRRVRWPGFHMLNDSTQANNYTVAQFIQGNLWLPSTGVRYTA 524          

Query:  130 LKVSATEFAGSLKDTIDAVQQVASILSQFANAFGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSNQQGPNG--------QIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFG 1548
            + V   EFAGSL+ TIDA+++V  I+SQF + FGDFRL+NAISDCLDLLDFSAD+L+WSLSASQN  GK+NSTG ++SDLRTWLSAA+ NQ+TC  GFEGTN I + +++ GL QVTSLV +LLT V P  +    NG        + PSW + +D+KLLQA+GV+ DA+VA DGTG FTN+ DAV AAPDYSM R+VIYIK+G Y+ENVEIKKKKWNLMM+GDG++ TIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGP+KHQAVALRSDSDLSVF+RC I+GYQD+LYTHTMRQF+R+C+I+GTVDFIFGDA+VVFQNCQILAK+GLPNQKN+ITAQGRKDPN+PTG SIQFCNI+AD+DL    VNSTPTYLGRPWKLYSRT+IMQS++ N +RP+GWLEWN DFAL++L+Y E+MN+GPGAGLG RV+WPGY   N S QA N+TVA+ IEG+LWLPSTGVKYTA  G
Sbjct:   34 VNVPPAEFAGSLRTTIDAIRKVIPIVSQFGSFFGDFRLSNAISDCLDLLDFSADQLSWSLSASQNPNGKHNSTGDVASDLRTWLSAAMANQETCIEGFEGTNGIAKTVVAGGLNQVTSLVSDLLTMVQPPGSDSRSNGDRKVAEKNRFPSWFEREDQKLLQANGVTADAVVALDGTGTFTNIMDAVAAAPDYSMNRHVIYIKKGLYKENVEIKKKKWNLMMVGDGINGTIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPQKHQAVALRSDSDLSVFFRCAIKGYQDSLYTHTMRQFFRECRITGTVDFIFGDASVVFQNCQILAKQGLPNQKNTITAQGRKDPNQPTGFSIQFCNISADADL-LPFVNSTPTYLGRPWKLYSRTIIMQSYIGNAVRPQGWLEWNQDFALDTLYYAEFMNFGPGAGLGGRVQWPGYHALNNSAQAGNFTVARLIEGDLWLPSTGVKYTAGLG 513          

Query:  130 LKVSATEFAGSLKDTIDAVQQVASILSQFANA-FGDFRLANAISDCLDLLDFSADELNWSLSASQNQKGKNNSTGKLSSDLRTWLSAALVNQDTCSNGFEGTNSIVQGLISAGLGQVTSLVQELLTQVHPNSN---QQGPNGQIPSWVKTKDRKLLQADGVSVDAIVAQDGTGNFTNVTDAVLAAPDYSMRRYVIYIKRGTYRENVEIKKKKWNLMMIGDGMDATIISGNRSFVDGWTTFRSATFAVSGRGFIARDITFENTAGPEKHQAVALRSDSDLSVFYRCNIRGYQDTLYTHTMRQFYRDCKISGTVDFIFGDATVVFQNCQILAKKGLPNQKNSITAQGRKDPNEPTGISIQFCNITADSDLEAASVNSTPTYLGRPWKLYSRTVIMQSFLSNVIRPEGWLEWNGDFALNSLFYGEYMNYGPGAGLGSRVKWPGYQVFNESTQAKNYTVAQFIEGNLWLPSTGVKYTAEFGV 1551
            LKV+ +EF G+++D +  +Q+V SILSQF  + FGD RL+NA+SDC+D+LD S+D L WS SA+QN KGK+NSTG ++SD+RTWLS+AL N +TC +GFEGT+ I   L+S GL Q+ S++ ELLTQV PN +   Q+   G+ PSWVK  DRKLLQA+GV+VD +VA DG+GNFT V DAV AAPDYSM+RYVIY+KRG Y ENVEIKKKKWNLMM+GDGM+ATII+GNRSF+DGWTTFRSATFAVSGRGFIARDI+F+NTAGPEKHQAVALRSDSDLSVFYRC I GYQD+LYTHTMRQF+R+CKISGTVDFIFGDAT +FQNCQIL KKGLPNQKN+ITA GRKDPNEPTG SIQFCNITAD+DL   SVNST TYLGRPWK YSRT+ MQS +S+V+RPEGWLEWNGDFAL++L+Y EYMNYG GAGL  RVKWPGY + N+S+QA N+TV QFIEGNLWLP+TGV +TA  GV
Sbjct:   51 LKVAPSEFVGTVQDVVGILQEVMSILSQFGGSGFGDSRLSNAVSDCIDMLDLSSDALTWSASAAQNPKGKHNSTGNVNSDVRTWLSSALANPETCMDGFEGTSGIESQLVSTGLSQMMSMLAELLTQVDPNLDSFTQKEQKGRFPSWVKRDDRKLLQANGVNVDVVVATDGSGNFTKVMDAVHAAPDYSMKRYVIYVKRGVYIENVEIKKKKWNLMMVGDGMNATIITGNRSFIDGWTTFRSATFAVSGRGFIARDISFQNTAGPEKHQAVALRSDSDLSVFYRCGIFGYQDSLYTHTMRQFFRECKISGTVDFIFGDATTLFQNCQILVKKGLPNQKNTITAHGRKDPNEPTGFSIQFCNITADTDL-LPSVNSTYTYLGRPWKEYSRTIFMQSHISDVLRPEGWLEWNGDFALDTLYYAEYMNYGSGAGLNKRVKWPGYHIMNDSSQASNFTVTQFIEGNLWLPTTGVAFTAGLGV 527