ppa005749m, ppa005749m (mRNA) Prunus persica

Query:    1 MKKLCLPVLSLFLIICLSPQLLKAQ-DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPAS-PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEK--MASSSVNDEL 1335
            M+K  L V    L I  S QL ++    D+ RQPPRR+IFT H RSDSDPQQVHISLVG+D M+VSW+TD K  +S+VEYGK PGKY + ATGE TSY YFFYSSGKIHHV IGPLE  T+YYYRCGGS QEF FKTPP   P+EFAV GDLGQTEWT STL H+   +YDVLLLPGDLSYAD+HQPLWD FGR+VEPYAS RPWMVT+GNHEIE FPIIYP GFKA+N+RW MP+QESGSTSNLYYSFEVAG HVIMLGSY EFD +S QY+WL+ DL K+DR++TPW++VL+HAPWYNTN AH+GEGESMR+AME+LLY ARVDVVFAGHVHAYERFTR+Y N+AD CGP+++TIGDGGNREGLALTFE+P S  LS+YREPSFGHGRLRI+N+THAFW WHRNNDS+ ++ D  WL+SLS S+ C +         + S ++NDEL
Sbjct:   75 MEKSWLTVSFHLLTILSSIQLPRSHASSDYSRQPPRRLIFTPHHRSDSDPQQVHISLVGRDRMKVSWITDDKSARSIVEYGKMPGKYEASATGEHTSYNYFFYSSGKIHHVEIGPLEAGTVYYYRCGGSGQEFYFKTPPSSFPIEFAVVGDLGQTEWTASTLTHVNRTNYDVLLLPGDLSYADSHQPLWDCFGRLVEPYASHRPWMVTEGNHEIEIFPIIYPDGFKAFNSRWPMPFQESGSTSNLYYSFEVAGCHVIMLGSYAEFDEKSAQYKWLKGDLGKVDRRRTPWLIVLIHAPWYNTNLAHKGEGESMRKAMEKLLYEARVDVVFAGHVHAYERFTRVYKNKADECGPIHVTIGDGGNREGLALTFEKPTSASLSVYREPSFGHGRLRILNQTHAFWSWHRNNDSDCILADSLWLQSLSVSRQCTQFQQDQASLPLVSVNLNDEL 523          

Query:   19 PVLSLFLIICLSPQLLKAQDDDFIRQPPRRVI-FTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSS 1269
            P L L LI+ +S  +      D++R  PR+ + F    ++ S PQQVHISL  + HMR++W+TD ++  S+V+YG +PGKY S   G  TSY Y FYSSGKIHH  IGPLE  T+YYYRCGG   EF  KTPP + P+ FAVA DLGQT WT STL+HI   +YDV LLPGDLSYAD  Q  WD+FG +V+P AS RPWMVT+GNHE E+ P  +  GF++YN+RW MPYQESGS SNLYYSFEVAG HV+MLGSY  +D  S+QY WL+ DL+++DRK+TPW++VLLH PWYN+N AHQGEG+ M + +E LLY A VD+VFAGHVHAYER  R+YN  +DPCGP+++TIGDGGNREGLA  + +P    S++RE SFGHG L+IVN THAFW WHRN+D   V  D+ W+ SL  S
Sbjct:    3 PKLILILILVISVSVTA----DYVRPKPRKALHFPWKPKAPSLPQQVHISLSSEKHMRITWITDDEYAPSIVQYGTSPGKYTSITLGGSTSYSYLFYSSGKIHHTVIGPLEHDTIYYYRCGGQGPEFQLKTPPAQFPITFAVAADLGQTGWTKSTLDHIDGCNYDVHLLPGDLSYADYLQRRWDTFGELVQPLASARPWMVTEGNHEQENIPF-FKDGFESYNSRWTMPYQESGSPSNLYYSFEVAGVHVVMLGSYAAYDLNSNQYSWLKTDLSRVDRKRTPWLLVLLHVPWYNSNKAHQGEGDRMMETLEPLLYAANVDLVFAGHVHAYERSKRVYNGRSDPCGPIHITIGDGGNREGLATRYNDPQPEWSVFREASFGHGELKIVNLTHAFWSWHRNDDDEPVRSDEVWITSLVGS 415          

Query:   94 QPPRRVIFTKHTRSDSDP---QQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGES--MRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTC 1278
            +PP R ++      D DP   +QVHIS+VG D MR++WVT  +   + V YG A G+  S ATG   SYKY  Y+SG IH V IGPL   T+YYYRCG S  EFSFKTPP + P+  AVAGD GQTEWT STL+HI   +YD+LLL GDLSYAD +QPLWDSFGR+VEP AS+RPWM   GNH++E   +++P    +YNARW MP++ESGSTSNLYYSFEVAG HV++LGSY +F ++SDQY+WLQADL K+DRK+TPW+VV+LHAPWYN+N+AHQGE ES  MR +MEE+LY ARVDVVFAGHVHAYERF R+Y  + D CGPVY+TIGDGGNREGLA  + +P   +SL+RE SFGHG+L +V+     W WHRN+D  SV  D   L+SL++   C
Sbjct:  438 RPPARKMYIVLDDDDQDPTHPEQVHISMVGADKMRITWVTKDET-PAEVHYGTAQGQLGSSATGSTRSYKYVVYTSGTIHDVVIGPLNANTVYYYRCGSSGPEFSFKTPPSQFPIRIAVAGDFGQTEWTKSTLDHISKSNYDLLLLAGDLSYADFYQPLWDSFGRLVEPLASQRPWMTATGNHDVEKIIVVHPEKCTSYNARWHMPFEESGSTSNLYYSFEVAGVHVVVLGSYSDFGSDSDQYKWLQADLGKVDRKRTPWLVVMLHAPWYNSNSAHQGEEESDGMRDSMEEILYKARVDVVFAGHVHAYERFDRVYQGKTDKCGPVYITIGDGGNREGLATKYIDPKPDISLFREASFGHGQLNVVDGNTMEWTWHRNDDDQSVASDSVTLKSLATEPGC 836          

Query:   94 QPPRRVIFTKHTRSDSDP---QQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGES--MRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSS 1266
            +PP R ++      D DP    QV IS+ G D MR++W+T  +   + V YG   G+  S ATG   SYKY  Y+SG IH V IGPL   T+YYYRCG S  EFSFKTPP + P+  AVAGD GQTEWT STL+HI   +YD+LLL GDLSYAD +QPLWDSFGR+VEP AS+RPWM   GNH++E   +++P  F +YNARW MP++ESGSTSNLYYSFEVAG HV++LGSY +F ++SDQY+WLQADL K+DRK+TPW+VV+LHAPWYN+N+AHQGE ES  MR +MEE+LY ARVDVVFAGHVHAYERF R+Y  + D CGPVY+TIGDGGNREGLA  + +P   +SL+RE SFGHG+L +V+E    W WHRN+D  SV  D   L+SL++
Sbjct:   28 RPPARKMYIVLDDEDQDPTHPDQVRISMAGADKMRITWMTKDET-PAEVHYGTVQGELGSSATGSTRSYKYATYTSGTIHDVLIGPLNANTVYYYRCGSSGPEFSFKTPPSQFPIRLAVAGDFGQTEWTKSTLDHISKSNYDLLLLAGDLSYADFYQPLWDSFGRLVEPLASQRPWMTATGNHDVEKIIVVHPEKFTSYNARWHMPFEESGSTSNLYYSFEVAGVHVVVLGSYTDFGSDSDQYKWLQADLGKVDRKRTPWLVVMLHAPWYNSNSAHQGEEESDGMRDSMEEILYKARVDVVFAGHVHAYERFDRVYQGKTDKCGPVYITIGDGGNREGLATKYNDPKPDISLFREASFGHGQLNVVDENTMEWTWHRNDDDQSVAADSVKLKSLAT 422          

Query:  145 PQQVHISLVGKDHMRV--SWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCG--GSEQEFSFKTPPQKLP---LEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQ-----PLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPT-GFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKD------QFWLESL 1260
            PQQVHI+    D   V  +WVT  + G S V YG    KY+  A G  T+Y +  YSSG IHH  +  LEP T YYY+ G  GS +EF F+TPP+  P     F + GDLGQT  + STLEH        +L  GDLSYAD ++       WDS+GR VE  A+ +PW+ T GNHE+E  P +     FK+Y  R+  PY  S S++ L+Y+   A  H+I+L SY  F   + Q++WL+ +L ++DR+KTPW++VL+HAP Y++N AH  EGESMR   E    +A+VD++FAGHVHAYER  RI N              D   PVY+T+GDGGN+EGLA  F +P    S +RE S+GH  L I N THAF+ W+RN+D   V  D      Q+W  +L
Sbjct:   62 PQQVHITQGDYDGKAVIITWVTTDEPGSSKVLYGTLEKKYDFSAEGNVTNYTFSNYSSGYIHHCLVHGLEPDTKYYYKIGDGGSSREFWFQTPPKIDPDTSYTFGIIGDLGQTYNSLSTLEHYMQSGAQTVLFVGDLSYADRYEFNDVGVRWDSWGRFVERSAAYQPWIWTAGNHEVEYMPNMGEVLPFKSYLHRYATPYMASQSSNPLWYAVRRASAHIIVLSSYSPFVKYTPQWKWLREELKRVDREKTPWLIVLMHAPMYSSNVAHYMEGESMRAVFESWFVHAKVDLIFAGHVHAYERSYRISNIHYNITNGDRYPIPDKSAPVYITVGDGGNQEGLAGRFVDPQPEYSSFREASYGHSTLEIKNRTHAFYHWNRNDDGKKVPTDSVVFYNQYWARNL 463          

Query:  145 PQQVHISLVGKDHMRVSWVT-DSKHGKSV-----------VEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKT----PPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA------------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEE--------------------------PAS---------PLSLYREPSFGHGRLRIVNETHAFWGWHRNND 1218
            P+Q+ +++     M VSW+T DS+ G +V           V YGK   KY+S  +G  T Y   +       Y+SG IHHV +  LEP T YYY+CG S      +E+ F+T     P++ P   AV GDLG T  T +T++H+   D  ++L+ GDLSYA                        +T+QP WD +GR +EP  S+ P MV +GNHEIE  P +    FK+Y  R+ +P +ESGS SN YYSF+  G H IMLG+YV+++    QY WL+ DL ++DR  TPW+V   H PWYN+ ++H  E E MRQ ME LLY   VD+VF+GHVHAYER  R+YN   D CGPVY+T+GDGGN E + +   +                          PA            S +RE SFGHG L +VN T+A W WHRN D
Sbjct:   55 PEQISLAISSPTSMWVSWITGDSQIGSNVTPLDPSTVASEVWYGKRSRKYSSVKSGFSTVYSQLYPFEGLLNYTSGIIHHVRLDDLEPGTKYYYKCGDSSFPAMSREYVFETLPLPGPKRYPRRIAVVGDLGLTSNTTTTIDHLIRNDPSMILMVGDLSYANQYRTTGGKGVPCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVAGITFKSYLTRFAVPSEESGSKSNFYYSFDAGGVHFIMLGAYVDYNRTGAQYAWLKKDLHQVDRSVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDSCGPVYITVGDGGNIEQVEVDHADDPGKCPSAQDNIPEFGGLCHLNFSSGPAKGKFCWDQQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 497          

Query:  145 PQQVHISLVGKDHMRV--SWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGG--SEQEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQ-----PLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPT-GFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYN-----NEADP------CGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKD------QFWLESLSSSK 1272
            PQQVHI+    D   V  SWVT  + G S V+YG +   Y+  A G  T+Y ++ Y SG IHH  +  LE  T YYY+ G   S QEF F+TPP+     P  F + GDLGQT  + STLEH    +   +L  GDLSYAD +Q       WD++GR VE  A+ +PW+ + GNHEIE  P +     FK+Y  R+  PY  S S+S L+Y+   A  H+I+L SY  F   + Q+ WL  +  +++R+KTPW++VL+H P YN+N AH  EGESMR A E      +VD+VFAGHVHAYER  RI N     +  DP        PVY+T+GDGGN+EGLA  F +P    S +RE S+GH  L I N THAF+ W+RN+D   V  D      Q+W   L S K
Sbjct:   41 PQQVHITQGDYDGKAVIVSWVTTDEPGPSKVQYGTSEKTYDYTAEGTTTNYTFYKYQSGYIHHCLVDGLEFDTKYYYKIGSGNSSQEFWFQTPPEIDPDAPYIFGIIGDLGQTYNSLSTLEHYMHSEGQTVLFLGDLSYADRYQYNDVGVRWDTWGRFVEQSAAYQPWIWSAGNHEIEYMPYMGEVLPFKSYLYRFPTPYAASKSSSPLWYAIRRASAHIIVLSSYSPFVTYTPQWLWLAEEFKRVNREKTPWLIVLMHVPIYNSNEAHFMEGESMRAAFESWFILNKVDIVFAGHVHAYERSYRISNIHYSVSSGDPYPVPDESAPVYITVGDGGNQEGLAGRFRDPQPDYSAFREASYGHSTLEIKNRTHAFYRWNRNSDGKQVSTDSFVLHNQYWASKLGSRK 446          

Query:   76 DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRV--SWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCG--GSEQEFSFKTPPQK---LPLEFAVAGDLGQTEWTNSTLEH--IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTG-FKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            D D  R PP            + PQQVHI+    +   V  SW+T  + G + V Y    GK+ S A G   +YKYF Y+SG IHH TI  L   T YYY  G   + ++F F TPP+    +P  F + GDLGQT  +N TL H  + +I    LL  GDLSYAD +       WD++GR +E   + +PW+ T GNHEI+  P I  T  FK Y  R+++P++ S STS L+YS + A  ++I++ SY  F   + QY+WL  +L K++R +TPW++VL+H P YN+   H  EGESMR   E      +VDVVFAGHVHAYER  R+ N              D   PVY+TIGDGGN++GLA    EP    S YRE SFGHG L I N THA++GW+RN D+ +V  D  WL +
Sbjct:   45 DSDVFRVPP----------GYNAPQQVHITQGDYEGNAVIISWITPDEPGSNTVLYWAENGKHKSHANGIVLTYKYFKYTSGYIHHCTIRNLVFDTKYYYEVGIGNTTRQFWFVTPPRAGPDVPYTFGLIGDLGQTYDSNRTLTHYELSTIKGQALLYVGDLSYADDYPFHDNIRWDTWGRFIERSCAYQPWIWTVGNHEIDFAPDIGETKPFKPYEYRYQVPFEASKSTSPLWYSIKRASAYIIVMSSYSAFGKSTPQYKWLSYELPKVNRTETPWLIVLMHCPMYNSYIHHYMEGESMRVIYEPWFVEYKVDVVFAGHVHAYERSERVSNIAYNIVNGKCTPIHDESAPVYITIGDGGNQKGLATGMTEPQPSYSAYREASFGHGILDIRNRTHAYFGWNRNQDAYAVEADSVWLHN 453          

Query:  142 DPQQVHISLVGK-DHMRVSWVT------------DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKTP----PQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-------EEPAS-----------------------------PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWL 1251
            +P+Q+ ++L    D + +SWVT            D K   S V YGK   +    + G    Y   +       Y+SG IHHV +  L+P T+YYY+CG +          FKT     P+  P   AV GDLG T  T ST+ H+ S + D+++  GD+ YA                       +T+QP WD +GR ++P  SK P MV +GNHEIE         F AY++R+  P +ESGS+S  YYSF   G H IMLG+Y+ +D   +QY+WL+ DL K+DRK TPW+V   H PWY+T  AH  E E MR A+E+LLYN  VD+VF+GHVHAYER  R+YN   DPCGPV++T+GDGGNRE +A+          EP++                               S YRE SFGHG L + NET A W WHRN D  ++  DQ ++
Sbjct:   68 EPEQISVTLSATYDSVWISWVTGEFQIGDNIKPLDPKSVASQVFYGKKKHRLVHMSNGHSLVYNQLYPFEGLQNYTSGIIHHVRLTGLKPETVYYYQCGDASIPALSDIHHFKTMVASGPRGYPNRIAVVGDLGLTYNTTSTISHLMSNNPDLIVFVGDVCYANMYLTNGTGSDCYSCSFSQTPIHETYQPRWDYWGRFMQPLISKIPIMVVEGNHEIEEQA--ENQTFVAYSSRFAFPSKESGSSSTFYYSFNAGGIHFIMLGAYISYDKSGEQYKWLERDLKKVDRKVTPWMVATWHPPWYSTYKAHYREAECMRVALEDLLYNYGVDIVFSGHVHAYERSNRVYNYTLDPCGPVHITVGDGGNREKMAIPHADEHGQCPEPSTTPDKYMGGFCAFNFTSGPAAGRFCWDRQPDYSAYRETSFGHGILEMKNETVALWTWHRNQDFYNLAGDQIYI 523          

Query:  145 PQQVHISLVGKDH--MRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCG--GSEQEFSFKTPPQK---LPLEFAVAGDLGQTEWTNSTLEH--IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTG-FKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEAD-----------PCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES---LSSSKTCLKS 1287
            PQQVHI+    +   + VSW T  + G S V Y     K  S A G   +YKYF Y+SG IHH TI  L   T YYY  G   S ++F F TPP+    +P  F + GDLGQT  +N TL H  +  I    +L  GDLSYAD +       WD++GR  E  A+ +PW+ T GNHEI+  P +  +  FK Y  R+ +P+  S STS L+YS + A  ++I++ SY  +D  + QY+WL  +L K++R +TPW++VL+H P YN+   H  EGE+MR   E      ++DVVFAGHVHAYER  RI N   D              PVY+TIGDGGN+EGLA    EP    S YRE SFGHG L I N THA++GW+RN D+ +V  D  WL++    SS K+ + S
Sbjct:   58 PQQVHITQGDYEGNAVLVSWTTPDEPGSSTVLYWAENSKTKSHAKGIVLTYKYFNYTSGYIHHCTIKNLTFDTKYYYEVGIGNSTRQFWFVTPPRAGPDVPYTFGLIGDLGQTYHSNRTLTHYELSPIKGQTVLYVGDLSYADDYPFHDNVRWDTWGRFTERSAAYQPWIWTAGNHEIDFAPDLGESKPFKPYTNRYHVPFLASASTSPLWYSIKRASAYIIVMSSYSAYDKYTPQYKWLANELLKVNRTETPWLIVLIHCPIYNSYIHHYMEGETMRVMYEAWFVEYKIDVVFAGHVHAYERSERISNIAYDIVNGNCTPIPNESAPVYITIGDGGNQEGLATGMTEPQPSYSAYREASFGHGILDIKNRTHAYFGWNRNQDAYAVEADSVWLQNRYWTSSEKSSIAS 466          

Query:   76 DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDH----MRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSE--QEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEH--IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYP-TGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYN-----------NEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFW 1248
            D D   +PP            + PQQVHI+    DH    + VSWVT ++ G + V Y     K   +A     +YKY+ Y+SG IHH TI  LE  T YYY  G     ++F F TPP+    +P  F + GDLGQT  +N TL H  +       +L  GDLSYAD +       WD++GR VE  A+ +PW+ T GNHEI+  P I     FK +  R+ +P++ S STS  +YS + A  ++I+L SY  +   + QY+WLQ +L K++R +TPW++VL+H+PWYN+   H  EGE+MR   E      +VDVVFAGHVHAYER  R+ N              D   PVY+TIGDGGN EGLA    EP    S YRE SFGH    I N THA++ WHRN D  +V  D  W
Sbjct:   51 DSDVFAEPP----------GYNAPQQVHITQ--GDHSGKAVIVSWVTMAEPGSNTVLYWSEKSKVKMQAEASVVTYKYYNYASGYIHHCTIRNLEFDTKYYYEVGSGHVRRKFWFVTPPEVGPDVPYTFGLIGDLGQTYDSNMTLTHYELNPAKGKTVLYVGDLSYADNYPNHDNVRWDTWGRFVERSAAYQPWIWTTGNHEIDFAPEIGEFEPFKPFTHRYPVPFRASDSTSPSWYSVKRASAYIIVLASYSAYGKYTPQYEWLQQELPKVNRTETPWLIVLVHSPWYNSYNYHYMEGETMRVMFESWFVEYKVDVVFAGHVHAYERSERVSNIAYNIINGMCTPVKDQSAPVYITIGDGGNIEGLANNMTEPQPNYSAYREASFGHASFDIKNRTHAYYSWHRNEDGYAVEADSMW 456          

Query:    1 MKKLCLPVLSLFLIICLSPQLLKAQ-DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPAS-PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEK--MASSSVNDEL 1335
            M+K  L V    L I  S QL ++    D+ RQPPRR+IFT H RSDSDPQQVHISLVG+D M+VSW+TD K  +S+VEYGK PGKY + ATGE TSY YFFYSSGKIHHV IGPLE  T+YYYRCGGS QEF FKTPP   P+EFAV GDLGQTEWT STL H+   +YDVLLLPGDLSYAD+HQPLWD FGR+VEPYAS RPWMVT+GNHEIE FPIIYP GFKA+N+RW MP+QESGSTSNLYYSFEVAG HVIMLGSY EFD +S QY+WL+ DL K+DR++TPW++VL+HAPWYNTN AH+GEGESMR+AME+LLY ARVDVVFAGHVHAYERFTR+Y N+AD CGP+++TIGDGGNREGLALTFE+P S  LS+YREPSFGHGRLRI+N+THAFW WHRNNDS+ ++ D  WL+SLS S+ C +         + S ++NDEL
Sbjct:    1 MEKSWLTVSFHLLTILSSIQLPRSHASSDYSRQPPRRLIFTPHHRSDSDPQQVHISLVGRDRMKVSWITDDKSARSIVEYGKMPGKYEASATGEHTSYNYFFYSSGKIHHVEIGPLEAGTVYYYRCGGSGQEFYFKTPPSSFPIEFAVVGDLGQTEWTASTLTHVNRTNYDVLLLPGDLSYADSHQPLWDCFGRLVEPYASHRPWMVTEGNHEIEIFPIIYPDGFKAFNSRWPMPFQESGSTSNLYYSFEVAGCHVIMLGSYAEFDEKSAQYKWLKGDLGKVDRRRTPWLIVLIHAPWYNTNLAHKGEGESMRKAMEKLLYEARVDVVFAGHVHAYERFTRVYKNKADECGPIHVTIGDGGNREGLALTFEKPTSASLSVYREPSFGHGRLRILNQTHAFWSWHRNNDSDCILADSLWLQSLSVSRQCTQFQQDQASLPLVSVNLNDEL 449          

Query:   10 LCLPVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            +  P+L   L   L PQ L +Q++ F+RQP  ++I T H  S SDPQQVHISLVGK+ MRVSW+T+ KH +SVVEYG   G+Y  KATG  TSY+YF Y+SGKIH+V IGPL+P T Y+YRCGGS  +FSFKTPP K P+EF + GDLGQTEWT STL+H+ S DYDV LLPGDLSYAD+ QPLWDSFGR+VEPYASKRPWMVT+GNHEIESFPIIYP GF+AYNARW MP+Q+SGSTSNLYYSFEV  TH IMLGSY +FDA+S QY WLQ+DLA IDR KTPWV+VLLHAPWYNTN AHQGEGESMRQAMEELLY ARVD+VFAGHVHAYERFTRIY+N+AD CGP+Y+TIGDGGNREGLAL F+ P SPLSLYREPSFGHGRLRI+NETHA W WHRNND+++VV D  W+ESLSSSK C K+ +Q +     + N+EL
Sbjct:    1 MAFPILLHTLCFLLFPQPLLSQEN-FVRQPAGQLIITPHHGSHSDPQQVHISLVGKEKMRVSWITEDKHTESVVEYGTKAGEYREKATGLHTSYQYFLYNSGKIHNVVIGPLQPGTTYFYRCGGSGPDFSFKTPPPKFPIEFVIVGDLGQTEWTASTLKHVDSNDYDVFLLPGDLSYADSQQPLWDSFGRLVEPYASKRPWMVTEGNHEIESFPIIYPQGFQAYNARWPMPFQQSGSTSNLYYSFEVTATHFIMLGSYTDFDAQSQQYTWLQSDLANIDRAKTPWVIVLLHAPWYNTNEAHQGEGESMRQAMEELLYEARVDLVFAGHVHAYERFTRIYDNKADSCGPMYVTIGDGGNREGLALMFKNPPSPLSLYREPSFGHGRLRILNETHAHWSWHRNNDADAVVADGVWIESLSSSKACSKTPDQQD-----AANEEL 436          

Query:   34 FLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            F ++  + Q   ++D+ + R P R +IFT H   +S+ QQVH+SLVG+DHMRV+W+TD KH  S VEYGK PG YN+ ATG+ TSY+YFFYSSGKIHHV IGPLEP T YYYRCGGS  E SFKTPP  LPLEF V GDLGQT WTNSTL H+ S DYDVLLLPGDLSYADT+QPLWDSFGR+VE YAS+RPWMVT+GNHE E FPII P GFKAYNARW MPY+ES S+SNLYYSF V GTHVIMLGSY +FD  S QY+WL+ADL  IDRKKTPWV+VLLHAPWYNTN AHQGEGESMR+AMEELLY ARVDVVFAGHVHAYERF RIY+N+ DPCGPVY+TIGDGGNREGLALTF+ PASPLSLYRE SFGHGRLRI++ET A W WHRNNDSNS   D+ WL+S+S+S  C  +++  ++      NDEL
Sbjct:   14 FFLLQFTSQCYASKDESYSRPPARNIIFTAHHGLESEAQQVHVSLVGRDHMRVTWITDDKHAPSTVEYGKQPGTYNAMATGDHTSYRYFFYSSGKIHHVKIGPLEPGTTYYYRCGGSGPELSFKTPPATLPLEFVVIGDLGQTGWTNSTLAHVNSRDYDVLLLPGDLSYADTNQPLWDSFGRLVEKYASQRPWMVTEGNHETEIFPIIQPHGFKAYNARWLMPYEESNSSSNLYYSFNVVGTHVIMLGSYTDFDEHSQQYKWLEADLGSIDRKKTPWVIVLLHAPWYNTNNAHQGEGESMRKAMEELLYKARVDVVFAGHVHAYERFARIYDNKVDPCGPVYITIGDGGNREGLALTFQNPASPLSLYREASFGHGRLRIMDETRAHWSWHRNNDSNSFSADEVWLDSISTSTACW-AIDDEKEPPKFIANDEL 446          

Query:   19 PVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQ 1296
            P+L   +   L PQ L +Q+++F+RQP  ++I T H RS+S+PQQVHISLVGKD MRVSW+T+ K  +++VEYG   G+Y+ K  GE TSY+YFFY+SGKIH+  IGPLEP T Y+YRCGG   EFSFKTPP K P+EF + GDLGQTEWT STL+H+   DYDV L+PGDLSYAD+ QPLWDSFGR+VEPYASKRPWMVT+GNHEIE FPIIYP GF+AYN RW MP+QESGS SNLYYSFEVAG H+IMLGSY +F  ES QY+WLQ DL KIDR KTPWV+ ++HAPWY TN AHQGEGESMRQAMEELL+ ARVD+VFAGHVHAYERFTRIYNN+AD CGP+Y+TIGDGGNREGLAL F+ P SPLSL+REPSFGHGRLRI+NETHA W WHRNND +++V D  W+ESLS+ K C ++ NQ
Sbjct:   12 PILLQTICFLLFPQPLMSQENNFVRQPASQLIITPHQRSNSEPQQVHISLVGKDKMRVSWITEDKETETMVEYGTKAGEYSEKTMGEHTSYQYFFYNSGKIHNAVIGPLEPNTTYFYRCGGLGPEFSFKTPPSKFPIEFVIVGDLGQTEWTASTLKHVDKSDYDVFLIPGDLSYADSQQPLWDSFGRLVEPYASKRPWMVTEGNHEIEIFPIIYPKGFEAYNTRWPMPFQESGSNSNLYYSFEVAGVHIIMLGSYADFSVESQQYEWLQLDLTKIDRVKTPWVITMVHAPWYTTNEAHQGEGESMRQAMEELLFKARVDLVFAGHVHAYERFTRIYNNKADSCGPMYVTIGDGGNREGLALRFKNPPSPLSLFREPSFGHGRLRILNETHAHWSWHRNNDKDAIVADGIWIESLSNLKACSETPNQ 437          

Query:    1 MKKLCLPVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            MK L L  LS F ++ L P + +A   +  R+PPR ++F  + RS  DPQQVH+SL GKDHMRV+++T+    +SVVEYGK PGKY+ KATGE TSYKY FY SGKIHHV IGPL+P T YYYRCGG+  EFSFKTPP   P+EFA+ GDLGQTEWT +TL  I S DYDV LLPGDLSYADT QPLWDSFGR+VEP AS+RPWMVT+GNHEIE FPI   T FK+YNARW MP+ ES S SNLYYSF+VAG H +MLGSY +FD++SDQYQWLQADLAK+DRK TPWVVVLLHAPWYNTN AH+GEGESMR AME LL++ARVDVVF+GHVHAYERF R+YNN+ADPCGP+Y+TIGDGGNREGLAL+F++P SPLS YRE SFGHGRL++++   A W WHRNNDSNS++ D+ WLESLS+S +C  S   ++++
Sbjct:    1 MKLLGLFFLS-FTLLFLCPFISQADVPERSREPPRPIVFVHNDRSKFDPQQVHVSLAGKDHMRVTFITEDNKVESVVEYGKQPGKYDGKATGECTSYKYIFYKSGKIHHVKIGPLQPNTTYYYRCGGNGPEFSFKTPPSTFPVEFAIVGDLGQTEWTAATLSQIKSQDYDVFLLPGDLSYADTSQPLWDSFGRLVEPLASQRPWMVTEGNHEIEFFPIFEHTTFKSYNARWLMPHTESLSDSNLYYSFDVAGVHTVMLGSYTDFDSDSDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMRVAMECLLFSARVDVVFSGHVHAYERFKRVYNNKADPCGPIYITIGDGGNREGLALSFKKPPSPLSEYRESSFGHGRLKVMDGKRAHWSWHRNNDSNSLLADEVWLESLSTSSSCWPSSRSSDEL 435          

Query:  184 MRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQ 1296
            MRVSW+T+ KH +SVVEYG   G+Y++KATG  TSY+YFFY+SGKIH+V IGPL+P + Y+YRCGGS  EFSFKTPP + P+EF + GDLGQTEWT STL+HI S DYDV LLPGDLSYAD+ QPLWDSFGR+VEPYASKRPWMVT+GNHEIE FPIIYP GF+AYNARW MP+Q+SGSTSNLYYSFEVAGTHVIMLGSY +FD++S QY WLQ+DLA IDR KTPWV+VLLHAPWYNTN AHQGEGESMRQAMEELLY ARVD+VFAGHVHAYERFTRIY+N+AD CGP+Y+TIGDGGNREGLAL F+ P+SPLSLYREPSFGHGRLRI+NETHA W WHRNND+++VV D  W+ESLSSSK C K+  Q
Sbjct:    1 MRVSWITEDKHAESVVEYGTKAGEYSAKATGVYTSYQYFFYNSGKIHNVVIGPLQPGSTYFYRCGGSGPEFSFKTPPPRCPIEFVIVGDLGQTEWTASTLKHIDSSDYDVFLLPGDLSYADSQQPLWDSFGRLVEPYASKRPWMVTEGNHEIEIFPIIYPQGFQAYNARWPMPFQQSGSTSNLYYSFEVAGTHVIMLGSYTDFDSQSLQYTWLQSDLANIDRVKTPWVIVLLHAPWYNTNEAHQGEGESMRQAMEELLYEARVDLVFAGHVHAYERFTRIYDNKADSCGPMYVTIGDGGNREGLALMFKNPSSPLSLYREPSFGHGRLRILNETHAHWSWHRNNDADAVVADGVWIESLSSSKACSKTPYQ 371          

Query:  184 MRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            MRVSW+T+ KH +SVVEYG   G+Y  KATG  TSY+YF Y+SGKIH+V IGPL+P T Y+YRCGGS  +FSFKTPP K P+EF + GDLGQTEWT STL+H+ S DYDV LLPGDLSYAD+ QPLWDSFGR+VEPYASKRPWMVT+GNH+IESFPIIYP GF+AYNARW MP+Q+SGSTSNLYYSFEV  TH IMLGSY EFDA+S QY WLQ+DLA IDR KTPWV+VLLHAPWYNTN AHQGEGESMRQAMEELLY ARVD+VFAGHVHAYERFTRIY+N+AD CGP+Y+TIGDGGNREGLAL F+ P SPLSLYREPSFGHGRLRI+NETHA W WHRNND+++VV D  W+ESLSSSK C K+ +Q +     + N+EL
Sbjct:    1 MRVSWITEDKHTESVVEYGTKAGEYREKATGLHTSYQYFLYNSGKIHNVVIGPLQPGTTYFYRCGGSGPDFSFKTPPPKFPIEFVIVGDLGQTEWTASTLKHVDSNDYDVFLLPGDLSYADSQQPLWDSFGRLVEPYASKRPWMVTEGNHKIESFPIIYPQGFQAYNARWPMPFQQSGSTSNLYYSFEVTATHFIMLGSYTEFDAQSQQYTWLQSDLANIDRAKTPWVIVLLHAPWYNTNEAHQGEGESMRQAMEELLYEARVDLVFAGHVHAYERFTRIYDNKADSCGPMYVTIGDGGNREGLALMFKNPPSPLSLYREPSFGHGRLRILNETHAHWSWHRNNDADAVVADGVWIESLSSSKACSKTPDQQD-----AANEEL 379          

Query:   82 DFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPII--YPTGFKAYNARWRMPYQESGSTSNLYYSFEVAG--THVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEE--PASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            +++R PP RVIFT+HT+  S PQQVH+SLVG +HMRVSW+T+ KH KSVVEYGK  G Y + ATGE TSY+YF YSSGKIHHV IGPL+P T+YYYRCG +  EF  +TPP  LP+E AVAGDLGQTEWT STL H+G  DYDVLL+PGDLSYAD  QPLWDSFGR V+ YAS+RPWMVT+GNHE+E+   +  +P  F AY ARWRMPY+ESGS ++LYYSF+ AG   HV+MLGSY +F++ S+QY+WL  DLA +DR  TPWVVVLLHAPWYNTN AH+GEGE+MR+AME LLY ARVD+VFAGHVHAYERFTR+YNNEA+PCGPV++TIGDGGNREGLA  F +    +PLSL RE SFGHGRL +VN T A W WHRN+D++S V+D+ WLESL+++  C +S   +   A+ S NDEL
Sbjct:   31 EYVRPPPGRVIFTEHTKPTSHPQQVHVSLVGANHMRVSWITEDKHVKSVVEYGKVSGNYTASATGEHTSYRYFLYSSGKIHHVKIGPLDPGTVYYYRCGMAGDEFGLRTPPAALPVELAVAGDLGQTEWTASTLSHVGRSDYDVLLVPGDLSYADAQQPLWDSFGRFVQKYASRRPWMVTEGNHEVEAAMALPGWPRPFTAYAARWRMPYEESGSGTSLYYSFDAAGGAVHVVMLGSYADFNSSSEQYRWLARDLAAVDRGATPWVVVLLHAPWYNTNAAHEGEGEAMRKAMERLLYEARVDIVFAGHVHAYERFTRVYNNEANPCGPVHITIGDGGNREGLAFDFRKNHKLAPLSLMREASFGHGRLSVVNATAARWTWHRNDDADSTVRDEIWLESLAANGACQQS--SSAAAAADSQNDEL 452          

Query:   82 DFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPII--YPTGFKAYNARWRMPYQESGSTSNLYYSFEVAG--THVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEE--PASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            +++R PP RVIFT+HT+  S PQQVH+SLVG +HMRVSW+T+ KH KSVVEYGK  G Y + ATGE TSY+YF YSSGKIHHV IGPL+P T+YYYRCG +  EF  +TPP  LP+E AVAGDLGQTEWT STL H+G  DYDVLL+PGDLSYAD  QPLWDSFGR V+ YAS+RPWMVT+GNHE+E+   +  +P  F AY ARWRMPY+ESGS ++LYYSF+ AG   HV+MLGSY +F++ S+QY+WL  DLA +DR  TPWVVVLLHAPWYNTN AH+GEGE+MR+AME LLY ARVD+VFAGHVHAYERFTR+YNNEA+PCGPV++TIGDGGNREGLA  F +    +PLSL RE SFGHGRL +VN T A W WHRN+D++S V+D+ WLESL+++  C +S   +   A+ S NDEL
Sbjct:   31 EYVRPPPGRVIFTEHTKPASHPQQVHVSLVGANHMRVSWITEDKHVKSVVEYGKVSGNYTASATGEHTSYRYFLYSSGKIHHVKIGPLDPGTVYYYRCGMAGDEFGLRTPPAALPVELAVAGDLGQTEWTASTLSHVGRSDYDVLLVPGDLSYADAQQPLWDSFGRFVQKYASRRPWMVTEGNHEVEAAMALPGWPRPFTAYAARWRMPYEESGSGTSLYYSFDAAGGAVHVVMLGSYADFNSSSEQYRWLARDLAAVDRGATPWVVVLLHAPWYNTNAAHEGEGEAMRKAMERLLYEARVDIVFAGHVHAYERFTRVYNNEANPCGPVHITIGDGGNREGLAFDFRKNHKLAPLSLMREASFGHGRLSVVNATAARWTWHRNDDADSTVRDEIWLESLAANGACQQS--SSAAAAADSQNDEL 452          

Query:   82 DFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPII--YPTGFKAYNARWRMPYQESGSTSNLYYSFEVAG--THVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEE--PASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            +++R PP RVIFT+HT+  S PQQVH+SLVG +HMRVSW+T+ KH KSVVEYGK  G Y + ATGE TSY+YF YSSGKIHHV IGPL+P T+YYYRCG +  EF  +TPP  LP+E AVAGDLGQTEWT STL H+G  DYDVLL+PGDLSYAD  QPLWDSFGR V+ YAS+RPWMVT+GNHE+E+   +  +P  F AY ARWRMPY+ESGS ++LYYSF+ AG   HV+MLGSY +F++ S+QY+WL  DLA +DR  TPWVVVLLHAPWYNTN AH+GEGE+MR+AME LLY ARVD+VFAGHVHAYERFTR+YNNEA+PCGPV++TIGDGGNREGLA  F +    +PLSL RE SFGHGRL +VN T A W WHRN+D++S V+D+ WLESL+++  C +S   +   A+ S NDEL
Sbjct:   31 EYVRPPPGRVIFTEHTKPASHPQQVHVSLVGANHMRVSWITEDKHVKSVVEYGKVSGNYTASATGEHTSYRYFLYSSGKIHHVKIGPLDPGTVYYYRCGMAGDEFGLRTPPAALPVELAVAGDLGQTEWTASTLSHVGRSDYDVLLVPGDLSYADAQQPLWDSFGRFVQKYASRRPWMVTEGNHEVEAAMALPGWPRPFTAYAARWRMPYEESGSGTSLYYSFDAAGGAVHVVMLGSYADFNSSSEQYRWLARDLAAVDRGATPWVVVLLHAPWYNTNAAHEGEGEAMRKAMERLLYEARVDIVFAGHVHAYERFTRVYNNEANPCGPVHITIGDGGNREGLAFDFRKNHKLAPLSLMREASFGHGRLSVVNATAARWTWHRNDDADSTVRDEIWLESLAANGACQQS--SSAAAAADSQNDEL 452          

Query:   34 FLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            F ++ L P + +A   +  RQPPR ++F  + RS SDPQQVHISL GKDHMRV+++T+    +SVVEYGK PGKY+ KATGE TSYKYFFY SGKIHHV IGPL+  T YYYRCGG+  EFSFKTPP   P+EFA+ GDLGQTEWT +TL HI S DYDV LLPGDLSYADTHQPLWDSFGR+VEP ASKRPWMVT+GNHEIE FPII  T FK+YNARW MP+ ES STSNLYYSF+VAG H +MLGSY +FD ESDQYQWLQADLAK+DRK TPWVVVLLHAPWYNTN AH+GEGESMR+AME LL+NARVDVVF+GHVHAYERF R+YNN+ADPCGP+++TIGDGGNREGLAL+F++P SPLS +RE SFGHGRL++++   A W WHRNNDSNS++ D+ WL+SLS+S +C  S   N+++
Sbjct:   10 FTLLFLCPFISQADVPELSRQPPRPIVFVHNDRSKSDPQQVHISLAGKDHMRVTFITEDNKVESVVEYGKQPGKYDGKATGECTSYKYFFYKSGKIHHVKIGPLQANTTYYYRCGGNGPEFSFKTPPSTFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYADTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPLSEFRESSFGHGRLKVMDGKRAHWSWHRNNDSNSLLADEVWLDSLSTSSSCWPSSRSNDEL 434          

Query:    1 MKKLCL-PVLSLFLIICLSPQLLKAQ-DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTC 1278
            MKK+ +   L  F +  LSP + +A  D +F R PPR +    H R    PQQVHISL GKDHMRV++ TD  +  S+VEYGK P KY+ K  GE TSY YFFY+SGKIHHV IGPL+P T YYYRCGG   EFSFKTPP K P+EFAVAGDLGQT+WT  TL+ I   D+DV LLPGDLSYADTHQPLWDSFGR++E  AS RPWMVT+GNHEIESFP      FK+YNARW MP+ ES S SNLYYSF+VAG H +MLGSY  +++ SDQY WLQADL K+DRKKTPW+VV++H PWY+TN AH GEGE MR A+E LLY A+VDVVFAGHVH YERF  IYN +ADPCGP+Y+TIGDGGNREGLAL F++P SPLS +RE SFGHGRLRI++   A W WHRNND  S + D+   ES  +S  C
Sbjct:    1 MKKMKIFGFLISFSLFFLSPFVCQANYDSNFTRPPPRPLFIVSHGRPKFYPQQVHISLAGKDHMRVTYTTDDLNVASMVEYGKHPKKYDKKTAGESTSYTYFFYNSGKIHHVKIGPLKPNTKYYYRCGGHGDEFSFKTPPSKFPIEFAVAGDLGQTDWTVRTLDQIRKRDFDVFLLPGDLSYADTHQPLWDSFGRLLETLASTRPWMVTEGNHEIESFPTNDHISFKSYNARWLMPHAESLSHSNLYYSFDVAGVHTVMLGSYTPYESHSDQYHWLQADLRKVDRKKTPWLVVVMHTPWYSTNKAHYGEGEKMRSALESLLYRAQVDVVFAGHVHTYERFKPIYNKKADPCGPMYITIGDGGNREGLALRFKKPQSPLSEFRESSFGHGRLRIIDHKRAHWSWHRNNDEMSSIADEVSFESPRTSSHC 428          

Query:   31 LFLIICLSPQLL--KAQDDDFIRQPPRRVI-FTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            + L++ LS  ++   A  DD++R  PR  + F    +S S P+QVHISL G  HMRV+WVT+ K   S VEYG +PGKY+    GE TSY Y  Y SGKIHH  IGPLE  T+YYYRCGG   EF  KTPP + P+ FAVAGDLGQT WT STL+HI    Y V LLPGDLSYAD  Q  WD+FG +V+P AS RPWMVTQGNHE ES P I    F ++N+RW+MPY+ESGS SNLYYSFEVAG H IMLGSY ++D  SDQY WL+ADL+K+DR++TPW++VL H PWYN+N AHQ EG+ M   ME LLY + VD+VF GHVHAYER  R+ N ++DPCGPV++TIGDGGNREGLA  +++P+   S++RE SFGHG L++VN THA W WHRN+D      D+ WL SL +S    K   +  KM
Sbjct:    6 ILLLVTLSVSIIFTSAAADDYVRPKPRETLQFPWKQKSSSVPEQVHISLAGDKHMRVTWVTNDKSSPSFVEYGTSPGKYSYLGQGESTSYSYIMYRSGKIHHTVIGPLEADTVYYYRCGGEGPEFHLKTPPAQFPITFAVAGDLGQTGWTKSTLDHIDQCKYAVHLLPGDLSYADYMQHKWDTFGELVQPLASVRPWMVTQGNHEKESIPFIVDE-FVSFNSRWKMPYEESGSNSNLYYSFEVAGVHAIMLGSYTDYDRYSDQYSWLKADLSKVDRERTPWLIVLFHVPWYNSNNAHQHEGDEMMAEMEPLLYASGVDIVFTGHVHAYERTKRVNNGKSDPCGPVHITIGDGGNREGLARKYKDPSPEWSVFREASFGHGELQMVNSTHALWTWHRNDDDEPTRSDEVWLNSLVNSGCLKKRPQELRKM 433          

Query:   25 LSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSD--PQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-YSSGKIHHVTIGPLEPATMYYYRCGG--SEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGES--MRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTC 1278
            L   L+I L+  +L      + RQ  R+ +    T  D    P QVHISLVG D MR+SW+T S    SVV YG   GKY   A G  +SY Y   Y SG+I+ V IGPL+P T+YYY+CGG  S QEFSF+TPP K P++FAV+GDLG +EW+ STLEH+   DYDV +LPGDLSYA+ +QPLWD+FGR+V+P AS+RPWMVT GNHE+E  PI++   F AYN RWRMP++ESGS+SNLYYSF V G H+IMLGSY +F+  S+QYQWL+ +L KIDRK TPWVV ++HAPWYN+N AHQGE ES  M+++ME LLY ARVD+VFAGHVHAYERF+R+Y ++ D CGPVY+ IGDGGN EGLA  + +P   +SL+RE SFGHG+L + N THA W WHRN+D  SV KD  WL SL +  +C
Sbjct:    7 LVAILLIVLAGNVLS-----YDRQGTRKNLVIHPTNEDDPTFPDQVHISLVGPDKMRISWITQSSISPSVV-YGTVSGKYEGSANGTSSSYHYLLIYRSGQINDVVIGPLKPNTVYYYKCGGPSSTQEFSFRTPPSKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMYQPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYERFSRVYQDKFDKCGPVYINIGDGGNLEGLATKYRDPNPEISLFREASFGHGQLVVENATHARWEWHRNDDDVSVEKDSVWLTSLLADSSC 425          

Query:  142 DPQQVHISLVGK-DHMRVSWVT------------DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFK---------TPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLA-------------LTFEEPA--------------------SPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWL 1251
            +P+Q+ +SL    D + VSW+T            D     SVV++G      + +A G    Y   +       Y+SG IHHV I  L+P+T+YYYRCG   +    K         + P   P   AV GDLG T  T  T+ H+     D++LL GD+SYA                       +T+QP WD +GR +E   SK P MV +GNHEIE         F+AY++R+  P+ ESGS+S LYYSF   G H +MLG+Y+ +D  ++QY+WL+ DLAK+DR  TPW+V   H PWY++ TAH  E E M++AMEELLY+   D+VF GHVHAYER  R+YN E DPCGPVY+ IGDGGNRE +A             LT  +P                        S  RE SFGHG L + NET A W W+RN DS+S V DQ ++
Sbjct:   63 EPEQISLSLSSDHDSIWVSWITGEFQIGKKVKPLDPTSINSVVQFGTLRHSLSHEAKGHSLVYSQLYPFDGLLNYTSGIIHHVRITGLKPSTIYYYRCGDPSRRAMSKIHHFRTMPVSSPSSYPGRIAVVGDLGLTYNTTDTISHLIHNSPDLILLIGDVSYANLYLTNGTSSDCYSCSFPETPIHETYQPRWDYWGRFMENLTSKVPLMVIEGNHEIELQA--ENKTFEAYSSRFAFPFNESGSSSTLYYSFNAGGIHFVMLGAYIAYDKSAEQYEWLKKDLAKVDRSVTPWLVASWHPPWYSSYTAHYREAECMKEAMEELLYSYGTDIVFNGHVHAYERSNRVYNYELDPCGPVYIVIGDGGNREKMAIEHADDPGKCPEPLTTPDPVMGGFCAWNFTPSDKFCWDRQPDYSALRESSFGHGILEMKNETWALWTWYRNQDSSSEVGDQIYI 515          

Query:  145 PQQVHISLVGKDHMRV--SWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRC--GGSEQEFSFKTPPQKLP---LEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQ-----PLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYP-TGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            PQQVHI+    D   V  SWVT  + G S V YG   GKY   A G   +Y ++ Y SG IHH  +  LE  T YYY+   G S +EF F TPP   P    +F + GD+GQT  + STLEH        +L  GDLSYAD +Q       WDS+GR VE   + +PW+ + GNHE++  P +   T F+ Y  R+  PY  S S+S L+Y+   A  H+I+L SY  F   + Q+ WL  +L ++DR+KTPW++VL+H P YN+N AH  EGESMR A EE     +VDV+FAGHVHAYER  RI N              D   PVY+T+GDGGN+EGLA  F EP    S +RE S+GH  L I N THA + W+RN+D   V  D+F L +
Sbjct:   54 PQQVHITQGDYDGKAVIISWVTPDEPGSSQVHYGAVQGKYEFVAQGTYHNYTFYKYKSGFIHHCLVSDLEHDTKYYYKIESGESSREFWFVTPPHVHPDASYKFGIIGDMGQTFNSLSTLEHYMESGAQAVLFLGDLSYADRYQYNDVGVRWDSWGRFVERSTAYQPWLWSAGNHEVDYMPYMGEVTPFRNYLQRYTTPYLASKSSSPLWYAVRRASAHIIVLSSYSPFVKYTPQWHWLSEELTRVDREKTPWLIVLMHVPIYNSNEAHFMEGESMRAAFEEWFVQHKVDVIFAGHVHAYERSYRISNVRYNVSSGDRYPVPDKSAPVYITVGDGGNQEGLAGRFTEPQPDYSAFREASYGHSTLDIKNRTHAIYHWNRNDDGKKVATDEFVLHN 448          

Query:   55 PQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVT-DSKHGKSV-----------VEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKTPP----QKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA------------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPASPLSLY 1137
            P L +  DD  +  P  R    K   S   P+Q+ ++L     M VSWVT D+  GK V           V YGK  G Y  K  G  T Y   +       Y+SG IHHV I  LEP T YYYRCG S      +E SF+T P       P   A  GDLG T  T +T++H+   D  ++++ GDL+YA                        +T+QP WD++GR +EP  SK P MV +GNHEIE  P      FK+Y+ R+ +P  ESGS SNLYYSF+  G H +MLG+YV+++    QY WL+ DL+K+DR  TPW+V  +H PWYN+ ++H  E E MRQ MEELLY  RVD+VFAGHVHAYER  RIYN   DPCGPVY+TIGDGGN E + + F ++P    S Y
Sbjct:   39 PSLRRGSDDLPMDHPRLR----KRNVSSDFPEQIALALSTPTSMWVSWVTGDAIVGKDVKPLDPSSIASEVWYGKEKGNYMLKKKGNATVYSQLYPSDGLLNYTSGIIHHVLIDGLEPETRYYYRCGDSSVPAMSEEISFETLPLPSKDAYPHRIAFVGDLGLTSNTTTTIDHLMENDPSLVIIVGDLTYANQYRTIGGKGVPCFSCSFPDAPIRETYQPRWDAWGRFMEPLTSKVPTMVIEGNHEIE--PQASGITFKSYSERFAVPASESGSNSNLYYSFDAGGVHFVMLGAYVDYNNTGLQYAWLKEDLSKVDRAVTPWLVATMHPPWYNSYSSHYQEFECMRQEMEELLYQYRVDIVFAGHVHAYERMNRIYNYTLDPCGPVYITIGDGGNIEKVDVDFADDPGKCHSSY 446          

Query:   76 DDDFIRQPPRRVIFTKHTRSDSDPQQVHISL---VGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCG--GSEQEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEHI--GSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTG-FKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYN-----------NEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            D D  R PP            + PQQVHI+    VGK  M VSWVT  + G S V Y     ++   A G   +Y YF Y+SG IHH TI  LE  T YYY  G   + + F F TPP+    +P  F + GDLGQ+  +N TL H     I    +L  GDLSYAD +       WD++GR VE   + +PW+ T GNHEI+  P I  T  FK +  R+ +PY+ SGST   +Y  + A  ++I+L SY  +   + QY+WL+ +L K++R +TPW++VL+H+PWYN+   H  EGE+MR   E      +VD+VFAGHVHAYER  R+ N              D   PVY+TIGDGGN EGLA    +P    S +RE SFGH  L I N THA++ WHRN D  +V  D  W+ +
Sbjct:   43 DSDVFRVPP----------GYNAPQQVHITQGDHVGKA-MIVSWVTVDEPGSSKVVYWSENSQHKKVARGNIRTYTYFNYTSGYIHHCTIRNLEYNTKYYYEVGIGNTTRSFWFTTPPEVGPDVPYTFGLIGDLGQSFDSNRTLTHYERNPIKGQAVLFVGDLSYADNYPNHDNVRWDTWGRFVERSTAYQPWIWTAGNHEIDFAPEIGETKPFKPFTKRYHVPYKASGSTETFWYPIKRASAYIIVLSSYSAYGKYTPQYKWLEEELPKVNRTETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQHKVDLVFAGHVHAYERSERVSNVAYDIVNGKCTPVRDQSAPVYITIGDGGNLEGLATNMTDPQPEYSAFREASFGHATLDIKNRTHAYYSWHRNQDGYAVEADSMWVSN 451          

Query:   22 VLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHT----RSDSDPQQVHISLVGKDH----MRVSWVTD-SKHGKSVVEYGKA------PGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCG--GSEQEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEH-IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPII-YPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            +L +F+ + ++  +      +F+R        +  T       + P+QVHI  V  D+    + +SWVT  +  G +VV Y KA      P K    A+   +SY+++ Y+SG +HH TI  LE  T Y Y  G  GS ++FSF +PP+    +P  F + GDLGQT  +N TL H + +     +L PGDLSYAD H    Q  WDS+GR VEP A+ + ++   GNHEI+  P I  P  FK Y  R+   Y+ S S S L+YS   A  H+I+L SY  +   + QY WL+ +L K++R++TPW++V++H+PWYN+N  H  EGESMR   E    N++VD+V +GHVH+YER  R+ N +            DP  P+Y+TIGDGGN EG+A +F +P    S YRE SFGH  L I N THA++ WHRN D+  V  D   L +
Sbjct:    6 ILLVFVFLSIATVINSGTTSNFVRTAQPSTEMSLETFPSPAGHNAPEQVHI--VQGDYNGRGIIISWVTPLNLAGSNVVTYWKAVDGDVKPKKKRGHAS--TSSYRFYDYTSGFLHHATIKGLEYDTKYIYEVGTDGSVRQFSFTSPPKVGPDVPYTFGIIGDLGQTLASNETLYHYMSNPKGQAVLFPGDLSYADDHPNHDQRKWDSWGRFVEPCAAYQTFIYAAGNHEIDFVPNIGEPHAFKPYIHRYHNAYKASKSISPLWYSIRRASAHIIVLSSYSAYGKYTPQYVWLEQELKKVNREETPWLIVMVHSPWYNSNNYHYMEGESMRAMFESWFVNSKVDLVLSGHVHSYERSERVSNIKYNITNGLSYPVKDPSAPIYITIGDGGNIEGIANSFTDPQPSYSAYREASFGHAVLEIYNRTHAYYTWHRNQDNEPVAADSIMLHN 450          

Query:   22 VLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSD----SDPQQVHISLVGKDH--MRVSWVTD-SKHGKSVVEY-----GKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGG--SEQEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEH-IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPII-YPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            V+  FL + ++  +       F+RQ    +  +  T       + P+QVH++    D   M VSWVT  +  G +VV Y     G        +A     SY+++ YSSG +HH TI  LE  T Y Y  G   S ++FSF TPP+    +P  F + GDLGQT  +N TL H + +     +L  GDLSYAD H    Q  WD++GR +EP A+ +P++   GNHEI+  P I  P  FK Y  R+   Y+ S STS L+YS   A  H+I+L SY  +   + QY WL+ +L  ++R++TPW++V++H+PWYN+N  H  EGESMR   E  L N++VD+V +GHVHAYER  RI N +            DP  P+Y+TIGDGGN EG+A +F +P    S YRE SFGH  L I+N THA + WHRN D+  V  D   L +
Sbjct:    5 VIFAFLFLSITTVINGGITSKFVRQALPSIEMSLDTFPSPGGYNTPEQVHLTQGDHDGRGMIVSWVTPLNLAGSNVVTYWIATNGSDVKPAKKRAHASTKSYRFYDYSSGFLHHATIKGLEYDTKYIYEVGTDKSVRQFSFTTPPKIGPDVPYTFGIIGDLGQTYASNETLYHYMSNPKGQAVLFAGDLSYADDHPNHDQRKWDTWGRFMEPCAAYQPFIFAAGNHEIDFVPNIGEPHAFKPYTHRYPNAYKASQSTSPLWYSVRRASAHIIVLSSYSAYGKYTPQYIWLEQELKNVNREETPWLIVIVHSPWYNSNNYHYMEGESMRVMFESWLVNSKVDLVLSGHVHAYERSERISNIKYNITNGLSSPVKDPNAPIYITIGDGGNIEGIANSFVDPQPSYSAYREASFGHAVLEIMNRTHAQYTWHRNQDNEPVAADSIMLHN 450          

Query:   34 FLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            F ++ L P + +A   +  RQPPR ++F  + RS SDPQQVHISL GKDHMRV+++T+    +SVVEYGK PGKY+ KATGE TSYKYFFY SGKIHHV IGPL+  T YYYRCGG+  EFSFKTPP   P+EFA+ GDLGQTEWT +TL HI S DYDV LLPGDLSYADTHQPLWDSFGR+VEP ASKRPWMVT+GNHEIE FPII  T FK+YNARW MP+ ES STSNLYYSF+VAG H +MLGSY +FD ESDQYQWLQADLAK+DRK TPWVVVLLHAPWYNTN AH+GEGESMR+AME LL+NARVDVVF+GHVHAYERF R+YNN+ADPCGP+++TIGDGGNREGLAL+F++P SPLS +RE SFGHGRL++++   A W WHRNNDSNS++ D+ WL+SLS+S +C  S   N+++
Sbjct:   10 FTLLFLCPFISQADVPELSRQPPRPIVFVHNDRSKSDPQQVHISLAGKDHMRVTFITEDNKVESVVEYGKQPGKYDGKATGECTSYKYFFYKSGKIHHVKIGPLQANTTYYYRCGGNGPEFSFKTPPSTFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYADTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPLSEFRESSFGHGRLKVMDGKRAHWSWHRNNDSNSLLADEVWLDSLSTSSSCWPSSRSNDEL 434          

Query:    1 MKKLCL-PVLSLFLIICLSPQLLKAQ-DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTC 1278
            MKK+ +   L  F +  LSP + +A  D +F R PPR +    H R    PQQVHISL GKDHMRV++ TD  +  S+VEYGK P KY+ K  GE TSY YFFY+SGKIHHV IGPL+P T YYYRCGG   EFSFKTPP K P+EFAVAGDLGQT+WT  TL+ I   D+DV LLPGDLSYADTHQPLWDSFGR++E  AS RPWMVT+GNHEIESFP      FK+YNARW MP+ ES S SNLYYSF+VAG H +MLGSY  +++ SDQY WLQADL K+DRKKTPW+VV++H PWY+TN AH GEGE MR A+E LLY A+VDVVFAGHVH YERF  IYN +ADPCGP+Y+TIGDGGNREGLAL F++P SPLS +RE SFGHGRLRI++   A W WHRNND  S + D+   ES  +S  C
Sbjct:    1 MKKMKIFGFLISFSLFFLSPFVCQANYDSNFTRPPPRPLFIVSHGRPKFYPQQVHISLAGKDHMRVTYTTDDLNVASMVEYGKHPKKYDKKTAGESTSYTYFFYNSGKIHHVKIGPLKPNTKYYYRCGGHGDEFSFKTPPSKFPIEFAVAGDLGQTDWTVRTLDQIRKRDFDVFLLPGDLSYADTHQPLWDSFGRLLETLASTRPWMVTEGNHEIESFPTNDHISFKSYNARWLMPHAESLSHSNLYYSFDVAGVHTVMLGSYTPYESHSDQYHWLQADLRKVDRKKTPWLVVVMHTPWYSTNKAHYGEGEKMRSALESLLYRAQVDVVFAGHVHTYERFKPIYNKKADPCGPMYITIGDGGNREGLALRFKKPQSPLSEFRESSFGHGRLRIIDHKRAHWSWHRNNDEMSSIADEVSFESPRTSSHC 428          

Query:   31 LFLIICLSPQLL--KAQDDDFIRQPPRRVI-FTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            + L++ LS  ++   A  DD++R  PR  + F    +S S P+QVHISL G  HMRV+WVT+ K   S VEYG +PGKY+    GE TSY Y  Y SGKIHH  IGPLE  T+YYYRCGG   EF  KTPP + P+ FAVAGDLGQT WT STL+HI    Y V LLPGDLSYAD  Q  WD+FG +V+P AS RPWMVTQGNHE ES P I    F ++N+RW+MPY+ESGS SNLYYSFEVAG H IMLGSY ++D  SDQY WL+ADL+K+DR++TPW++VL H PWYN+N AHQ EG+ M   ME LLY + VD+VF GHVHAYER  R+ N ++DPCGPV++TIGDGGNREGLA  +++P+   S++RE SFGHG L++VN THA W WHRN+D      D+ WL SL +S    K   +  KM
Sbjct:    6 ILLLVTLSVSIIFTSAAADDYVRPKPRETLQFPWKQKSSSVPEQVHISLAGDKHMRVTWVTNDKSSPSFVEYGTSPGKYSYLGQGESTSYSYIMYRSGKIHHTVIGPLEADTVYYYRCGGEGPEFHLKTPPAQFPITFAVAGDLGQTGWTKSTLDHIDQCKYAVHLLPGDLSYADYMQHKWDTFGELVQPLASVRPWMVTQGNHEKESIPFIVDE-FVSFNSRWKMPYEESGSNSNLYYSFEVAGVHAIMLGSYTDYDRYSDQYSWLKADLSKVDRERTPWLIVLFHVPWYNSNNAHQHEGDEMMAEMEPLLYASGVDIVFTGHVHAYERTKRVNNGKSDPCGPVHITIGDGGNREGLARKYKDPSPEWSVFREASFGHGELQMVNSTHALWTWHRNDDDEPTRSDEVWLNSLVNSGCLKKRPQELRKM 433          

Query:   25 LSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSD--PQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-YSSGKIHHVTIGPLEPATMYYYRCGG--SEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGES--MRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTC 1278
            L   L+I L+  +L      + RQ  R+ +    T  D    P QVHISLVG D MR+SW+T S    SVV YG   GKY   A G  +SY Y   Y SG+I+ V IGPL+P T+YYY+CGG  S QEFSF+TPP K P++FAV+GDLG +EW+ STLEH+   DYDV +LPGDLSYA+ +QPLWD+FGR+V+P AS+RPWMVT GNHE+E  PI++   F AYN RWRMP++ESGS+SNLYYSF V G H+IMLGSY +F+  S+QYQWL+ +L KIDRK TPWVV ++HAPWYN+N AHQGE ES  M+++ME LLY ARVD+VFAGHVHAYERF+R+Y ++ D CGPVY+ IGDGGN EGLA  + +P   +SL+RE SFGHG+L + N THA W WHRN+D  SV KD  WL SL +  +C
Sbjct:    7 LVAILLIVLAGNVLS-----YDRQGTRKNLVIHPTNEDDPTFPDQVHISLVGPDKMRISWITQSSISPSVV-YGTVSGKYEGSANGTSSSYHYLLIYRSGQINDVVIGPLKPNTVYYYKCGGPSSTQEFSFRTPPSKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMYQPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYERFSRVYQDKFDKCGPVYINIGDGGNLEGLATKYRDPNPEISLFREASFGHGQLVVENATHARWEWHRNDDDVSVEKDSVWLTSLLADSSC 425          

Query:   25 LSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSD--PQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-YSSGKIHHVTIGPLEPATMYYYRCGG--SEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGES--MRQAMEELLYNARVDVVFAGHVHAYERF 1014
            L   L+I L+  +L      + RQ  R+ +    T  D    P QVHISLVG D MR+SW+T S    SVV YG   GKY   A G  +SY Y   Y SG+I+ V IGPL+P T+YYY+CGG  S QEFSF+TPP K P++FAV+GDLG +EW+ STLEH+   DYDV +LPGDLSYA+ +QPLWD+FGR+V+P AS+RPWMVT GNHE+E  PI++   F AYN RWRMP++ESGS+SNLYYSF V G H+IMLGSY +F+  S+QYQWL+ +L KIDRK TPWVV ++HAPWYN+N AHQGE ES  M+++ME LLY ARVD+VFAGHVHAYERF
Sbjct:    7 LVAILLIVLAGNVLS-----YDRQGTRKNLVIHPTNEDDPTFPDQVHISLVGPDKMRISWITQSSISPSVV-YGTVSGKYEGSANGTSSSYHYLLIYRSGQINDVVIGPLKPNTVYYYKCGGPSSTQEFSFRTPPSKFPIKFAVSGDLGTSEWSKSTLEHVSKWDYDVFILPGDLSYANMYQPLWDTFGRLVQPLASQRPWMVTHGNHELEKIPILHSNPFTAYNKRWRMPFEESGSSSNLYYSFNVYGVHIIMLGSYTDFEPGSEQYQWLENNLKKIDRKTTPWVVAVVHAPWYNSNEAHQGEKESVEMKESMETLLYKARVDLVFAGHVHAYERF 337          

Query:  142 DPQQVHISLVGK-DHMRVSWVT------------DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFK---------TPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLA-------------LTFEEPA--------------------SPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWL 1251
            +P+Q+ +SL    D + VSW+T            D     SVV++G      + +A G    Y   +       Y+SG IHHV I  L+P+T+YYYRCG   +    K         + P   P   AV GDLG T  T  T+ H+     D++LL GD+SYA                       +T+QP WD +GR +E   SK P MV +GNHEIE         F+AY++R+  P+ ESGS+S LYYSF   G H +MLG+Y+ +D  ++QY+WL+ DLAK+DR  TPW+V   H PWY++ TAH  E E M++AMEELLY+   D+VF GHVHAYER  R+YN E DPCGPVY+ IGDGGNRE +A             LT  +P                        S  RE SFGHG L + NET A W W+RN DS+S V DQ ++
Sbjct:   63 EPEQISLSLSSDHDSIWVSWITGEFQIGKKVKPLDPTSINSVVQFGTLRHSLSHEAKGHSLVYSQLYPFDGLLNYTSGIIHHVRITGLKPSTIYYYRCGDPSRRAMSKIHHFRTMPVSSPSSYPGRIAVVGDLGLTYNTTDTISHLIHNSPDLILLIGDVSYANLYLTNGTSSDCYSCSFPETPIHETYQPRWDYWGRFMENLTSKVPLMVIEGNHEIELQA--ENKTFEAYSSRFAFPFNESGSSSTLYYSFNAGGIHFVMLGAYIAYDKSAEQYEWLKKDLAKVDRSVTPWLVASWHPPWYSSYTAHYREAECMKEAMEELLYSYGTDIVFNGHVHAYERSNRVYNYELDPCGPVYIVIGDGGNREKMAIEHADDPGKCPEPLTTPDPVMGGFCAWNFTPSDKFCWDRQPDYSALRESSFGHGILEMKNETWALWTWYRNQDSSSEVGDQIYI 515          

Query:  145 PQQVHISLVGKDHMRV--SWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRC--GGSEQEFSFKTPPQKLP---LEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQ-----PLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYP-TGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            PQQVHI+    D   V  SWVT  + G S V YG   GKY   A G   +Y ++ Y SG IHH  +  LE  T YYY+   G S +EF F TPP   P    +F + GD+GQT  + STLEH        +L  GDLSYAD +Q       WDS+GR VE   + +PW+ + GNHE++  P +   T F+ Y  R+  PY  S S+S L+Y+   A  H+I+L SY  F   + Q+ WL  +L ++DR+KTPW++VL+H P YN+N AH  EGESMR A EE     +VDV+FAGHVHAYER  RI N              D   PVY+T+GDGGN+EGLA  F EP    S +RE S+GH  L I N THA + W+RN+D   V  D+F L +
Sbjct:   54 PQQVHITQGDYDGKAVIISWVTPDEPGSSQVHYGAVQGKYEFVAQGTYHNYTFYKYKSGFIHHCLVSDLEHDTKYYYKIESGESSREFWFVTPPHVHPDASYKFGIIGDMGQTFNSLSTLEHYMESGAQAVLFLGDLSYADRYQYNDVGVRWDSWGRFVERSTAYQPWLWSAGNHEVDYMPYMGEVTPFRNYLQRYTTPYLASKSSSPLWYAVRRASAHIIVLSSYSPFVKYTPQWHWLSEELTRVDREKTPWLIVLMHVPIYNSNEAHFMEGESMRAAFEEWFVQHKVDVIFAGHVHAYERSYRISNVRYNVSSGDRYPVPDKSAPVYITVGDGGNQEGLAGRFTEPQPDYSAFREASYGHSTLDIKNRTHAIYHWNRNDDGKKVATDEFVLHN 448          

Query:   55 PQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVT-DSKHGKSV-----------VEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKTPP----QKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA------------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPASPLSLY 1137
            P L +  DD  +  P  R    K   S   P+Q+ ++L     M VSWVT D+  GK V           V YGK  G Y  K  G  T Y   +       Y+SG IHHV I  LEP T YYYRCG S      +E SF+T P       P   A  GDLG T  T +T++H+   D  ++++ GDL+YA                        +T+QP WD++GR +EP  SK P MV +GNHEIE  P      FK+Y+ R+ +P  ESGS SN YYSF+  G H +MLG+YV+++    QY WL+ DL+K+DR  TPW+V  +H PWYN+ ++H  E E MRQ MEELLY  RVD+VFAGHVHAYER  RIYN   DPCGPVY+TIGDGGN E + + F ++P    S Y
Sbjct:   39 PSLRRGSDDLPMDHPRLR----KRNVSSDFPEQIALALSTPTSMWVSWVTGDAIVGKDVKPLDPSSIASEVWYGKEKGNYMLKKKGNATVYSQLYPSDGLLNYTSGIIHHVLIDGLEPETRYYYRCGDSSVPAMSEEISFETLPLPSKDAYPHRIAFVGDLGLTSNTTTTIDHLMENDPSLVIIVGDLTYANQYRTIGGKGVPCFSCSFPDAPIRETYQPRWDAWGRFMEPLTSKVPTMVIEGNHEIE--PQASGITFKSYSERFAVPASESGSNSNFYYSFDAGGVHFVMLGAYVDYNNTGLQYAWLKEDLSKVDRAVTPWLVATMHPPWYNSYSSHYQEFECMRQEMEELLYQYRVDIVFAGHVHAYERMNRIYNYTLDPCGPVYITIGDGGNIEKVDVDFADDPGKCHSSY 446          

Query:   22 VLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHT----RSDSDPQQVHISLVGKDH----MRVSWVTD-SKHGKSVVEYGKA------PGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCG--GSEQEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEH-IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPII-YPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            +L +F+ + ++  +      +F+R        +  T       + P+QVHI  V  D+    + +SWVT  +  G +VV Y KA      P K    A+   +SY+++ Y+SG +HH TI  LE  T Y Y  G  GS ++FSF +PP+    +P  F + GDLGQT  +N TL H + +     +L PGDLSYAD H    Q  WDS+GR VEP A+ + ++   GNHEI+  P I  P  FK Y  R+   Y+ S S S L+YS   A  H+I+L SY  +   + QY WL+ +L K++R++TPW++V++H+PWYN+N  H  EGESMR   E    N++VD+V +GHVH+YER  R+ N +            DP  P+Y+TIGDGGN EG+A +F +P    S YRE SFGH  L I N THA++ WHRN D+  V  D   L +
Sbjct:    6 ILLVFVFLSIATVINSGTTSNFVRTAQPSTEMSLETFPSPAGHNAPEQVHI--VQGDYNGRGIIISWVTPLNLAGSNVVTYWKAVDGDVKPKKKRGHAS--TSSYRFYDYTSGFLHHATIKGLEYDTKYIYEVGTDGSVRQFSFTSPPKVGPDVPYTFGIIGDLGQTLASNETLYHYMSNPKGQAVLFPGDLSYADDHPNHDQRKWDSWGRFVEPCAAYQTFIYAAGNHEIDFVPNIGEPHAFKPYIHRYHNAYKASKSISPLWYSIRRASAHIIVLSSYSAYGKYTPQYVWLEQELKKVNREETPWLIVMVHSPWYNSNNYHYMEGESMRAMFESWFVNSKVDLVLSGHVHSYERSERVSNIKYNITNGLSYPVKDPSAPIYITIGDGGNIEGIANSFTDPQPSYSAYREASFGHAVLEIYNRTHAYYTWHRNQDNEPVAADSIMLHN 450          

Query:   22 VLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSD----SDPQQVHISLVGKDH--MRVSWVTD-SKHGKSVVEY-----GKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGG--SEQEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEH-IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPII-YPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            V+  FL + ++  +       F+RQ    +  +  T       + P+QVH++    D   M VSWVT  +  G +VV Y     G        +A     SY+++ YSSG +HH TI  LE  T Y Y  G   S ++FSF TPP+    +P  F + GDLGQT  +N TL H + +     +L  GDLSYAD H    Q  WD++GR +EP A+ +P++   GNHEI+  P I  P  FK Y  R+   Y+ S STS L+YS   A  H+I+L SY  +   + QY WL+ +L  ++R++TPW++V++H+PWYN+N  H  EGESMR   E  L N++VD+V +GHVHAYER  RI N +            DP  P+Y+TIGDGGN EG+A +F +P    S YRE SFGH  L I+N THA + WHRN D+  V  D   L +
Sbjct:    5 VIFAFLFLSITTVINGGITSKFVRQALPSIEMSLDTFPSPGGYNTPEQVHLTQGDHDGRGMIVSWVTPLNLAGSNVVTYWIATNGSDVKPAKKRAHASTKSYRFYDYSSGFLHHATIKGLEYDTKYIYEVGTDKSVRQFSFTTPPKIGPDVPYTFGIIGDLGQTYASNETLYHYMSNPKGQAVLFAGDLSYADDHPNHDQRKWDTWGRFMEPCAAYQPFIFAAGNHEIDFVPNIGEPHAFKPYTHRYPNAYKASQSTSPLWYSVRRASAHIIVLSSYSAYGKYTPQYIWLEQELKNVNREETPWLIVIVHSPWYNSNNYHYMEGESMRVMFESWLVNSKVDLVLSGHVHAYERSERISNIKYNITNGLSSPVKDPNAPIYITIGDGGNIEGIANSFVDPQPSYSAYREASFGHAVLEIMNRTHAQYTWHRNQDNEPVAADSIMLHN 450          

Query:  184 MRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            MRV+W+TD KH  S VEYGK PG YN+ ATG+ TSY+YFFYSSGKIHHV IGPLEP T YYYRCGGS  E SFKTPP  LPLEF V GDLGQT WTNSTL H+ S DYDVLLLPGDLSYADT+QPLWDSFGR+VE YAS+RPWMVT+GNHE E FPII P GFKAYNARW MPY+ES S+SNLYYSF V GTHVIMLGSY +FD  S QY+WL+ADL  IDRKKTPWV+VLLHAPWYNTN AHQGEGESMR+AMEELLY ARVDVVFAGHVHAYERF RIY+N+ DPCGPVY+TIGDGGNREGLALTF+ PASPLSLYRE SFGHGRLRI++ET A W WHRNNDSNS   D+ WL+S+S+S  C  +++  ++       DEL
Sbjct:    1 MRVTWITDDKHAPSTVEYGKQPGTYNAMATGDHTSYRYFFYSSGKIHHVKIGPLEPGTTYYYRCGGSGPELSFKTPPATLPLEFVVIGDLGQTGWTNSTLAHVNSRDYDVLLLPGDLSYADTNQPLWDSFGRLVEKYASQRPWMVTEGNHETEIFPIIQPHGFKAYNARWLMPYEESNSSSNLYYSFNVVGTHVIMLGSYTDFDEHSQQYKWLEADLGSIDRKKTPWVIVLLHAPWYNTNNAHQGEGESMRKAMEELLYKARVDVVFAGHVHAYERFARIYDNKVDPCGPVYITIGDGGNREGLALTFQNPASPLSLYREASFGHGRLRIMDETRAHWSWHRNNDSNSFSADEVWLDSISTSTACW-AIDDEKEPPKFIAKDEL 383          

Query:   19 PVLSLFLIICLSPQLLKAQDDDFIRQPPRRVI-FTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMAS 1314
            P L LF+ + +S     A   ++IR PPR+ + F  +++  S PQQVHISL G  HMRVSWV++ K    +VEYG +PG+Y++K+ GE TSY Y FYSSGKIHH  IGPLE  T+YYYRCGG   E+  KTPP + P+ FAVAGDLGQT WT STL+HI    YDV LLPGDLSYAD  Q  WD+FG +VEP AS RPWMVTQGNHE ES  + +  GF++YN+RW+MPY+ESGS+SNLYYSFEVAG H+IMLGSY ++D  SDQY WL+AD+AK+DRKKTPW++VL H PWYN+N AHQ EG+ M  AME LL+ A VD+V AGHVHAYER  R+   + DPCG V++TIGDGGNREGLA  ++ P    S++RE SFGHG L++ N THA+W WHRN+D  SV  DQ W+ SL +S    +  ++  K+ S
Sbjct:    3 PKLVLFVFLLISA----AATCEYIRPPPRKTLHFPWNSKLSSHPQQVHISLAGDKHMRVSWVSNDKSTLPMVEYGTSPGRYSNKSQGESTSYSYLFYSSGKIHHTIIGPLEDNTVYYYRCGGGGPEYKLKTPPAQFPVMFAVAGDLGQTGWTKSTLDHIDLCKYDVHLLPGDLSYADYIQHRWDTFGELVEPLASARPWMVTQGNHEKESI-MFFKDGFQSYNSRWKMPYEESGSSSNLYYSFEVAGAHIIMLGSYTDYDEHSDQYNWLKADVAKVDRKKTPWLIVLFHVPWYNSNEAHQDEGDRMLAAMEPLLHAASVDIVLAGHVHAYERTERVNKGKLDPCGAVHITIGDGGNREGLASKYKNPQPAWSVFREASFGHGELKLANSTHAYWSWHRNDDDESVRSDQVWITSLENSGCIAEKKHELMKILS 430          

Query:   22 VLSLFLIICLSPQLLKAQDDDFIRQPPRRVI-FTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSK 1272
            VL+LFL+I  +         ++IR   R+ + F++ ++S S PQQVHISL G  HMRVSWVTD K   S+VEYG +PG+Y++ A GE T Y Y FYSSGKIHH  IGPLE   +YYYRCGG   E+  KTPP + P+ FAVAGDLGQT WT STL+HI    YDV LLPGDLSYAD  Q LWD+FG +VEP AS RPWMVTQGNHE ES P +   GF+ YN+RW+MP++ESGS+SNLYYSFEV+G H+IMLGSY  +D  S+QY WL+ADLAK+DR KTPW++VL H PWYN+N AHQ EG+ M +AME LLY A VD+V AGHVHAYER  R+ N + DPCG V++TIGDGGNREGLA  ++ P    S++RE SFGHG L++ N THAFW WHRN+D   V  DQ W+ SL +S+
Sbjct:    6 VLALFLLISATAA------SEYIRPSTRKNLDFSRPSKSSSHPQQVHISLAGDKHMRVSWVTDDKSAASMVEYGTSPGRYSNIALGESTWYSYLFYSSGKIHHTVIGPLEDNAVYYYRCGGGGPEYKLKTPPAQFPVTFAVAGDLGQTGWTQSTLDHIDQCKYDVHLLPGDLSYADYMQHLWDTFGELVEPLASARPWMVTQGNHERESIPFL-KDGFEPYNSRWKMPFEESGSSSNLYYSFEVSGAHIIMLGSYTGYDEYSNQYNWLEADLAKVDRNKTPWLLVLFHVPWYNSNEAHQNEGDRMMEAMEPLLYAASVDIVLAGHVHAYERTERVNNGKLDPCGAVHITIGDGGNREGLAHKYKNPQPAWSVFREASFGHGELKLANSTHAFWSWHRNDDDEPVRSDQVWITSLVNSE 416          

Query:   64 LKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVT------------DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKT----PPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA------------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPAS----------------------------------PLSLYREPSFGHGRLRIVNETHAFWGWHRNND 1218
            L+   DD     PR     K   + + P+Q+ +++     M VSWVT            D     S V YGK  GKY S+  G  T Y   +       Y+SG IHHV I  LEP T Y+Y+CG S      +E  F+T     P   P   A+ GDLG T  +++T++H+   D  ++L+ GDL+YA                        +T+QP WD +GR +EP  S  P MV +GNHEIE  P +    FK+Y  R+ +P +ESGS SN YYSF+  G H +MLG+YV++++   QY WL+ DL ++DR KTPW+V   H PWYN+ ++H  E E MRQ ME LLY  RVD+VF+GHVHAYER  R+YN   DPCGPVY+T+GDGGN E + +   +EP +                                    S +RE SFGHG L +VN T+A W WHRN D
Sbjct:   48 LRRGSDDLPMNHPR----LKKNATSNFPEQISLAISSPTSMWVSWVTGEAQIGSDVIPLDPASVASEVWYGKESGKYASRGKGNSTVYTQLYPFEGLSNYTSGIIHHVRIDGLEPETKYFYKCGDSSIPAMSEEHVFETLPLPSPNAYPHRIAIIGDLGLTSNSSTTIDHVIVNDPSMILMVGDLTYANQYLTTGGKGAPCYSCAFPDAPIRETYQPRWDGWGRFMEPLISSSPMMVIEGNHEIE--PQVSGITFKSYLTRYAVPSEESGSNSNFYYSFDAGGIHFVMLGAYVDYNSTGAQYSWLKQDLNQVDRAKTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYRVDIVFSGHVHAYERMNRVYNYTLDPCGPVYITVGDGGNIEKVDVDHADEPGNCPSAGDNIPEFGGVCHINFSSGPAEGKFCWDKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQD 513          

Query:  142 DPQQVHISL-VGKDHMRVSWVT------------DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCG-----GSEQEFSFKTPP----QKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPAS-----------------------------------PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWL 1251
            +P+Q+ +SL    D + +SW+T            + K   SVV YG+       KATG    Y   +       Y+SG IHHV +  L+P T+Y+Y+CG         ++ FKT P    +  P   A+ GDLG T  T ST++H+   + D++LL GD+ YA                       +T+QP WD +GR ++P  SK P MV +GNHEIE    +    F AY++R+  P +ESGS+S  YYSF   G H IMLG Y+ ++  + QY+WL+ DLAK+DRK TPW+V   H PWY+T  AH  E E MR AME+LLY   VD++F GH+HAYER  R+YN   DPCGPV++T+GDGGNRE +A+   +EP +                                     S YRE SFGHG   + NETHA W WHRN D  +   DQ ++
Sbjct:   69 EPEQISVSLSTTHDSVWISWITGDFQIGDRIKPLNPKTVASVVRYGRLRIPLIHKATGYSLVYNQLYPFVGLQNYTSGIIHHVRLTGLKPNTLYHYQCGDPSIPAMSSKYYFKTMPASGPKSYPSRIAIVGDLGLTYNTTSTVDHVIGNNPDLILLVGDVCYANLYLTNGTGADCYSCSFSQTPIHETYQPRWDYWGRYMQPVTSKIPIMVVEGNHEIEKQ--VENQTFVAYSSRFAFPSKESGSSSTFYYSFNAGGIHFIMLGGYIAYNKSAHQYKWLKKDLAKVDRKVTPWLVATWHPPWYSTYKAHYREAECMRTAMEDLLYQYGVDIIFNGHIHAYERSNRVYNYTLDPCGPVHITVGDGGNREKMAIAHADEPRNCPDPSTTPDEYMGGFCAFNFTSGPAAGKFCWDRQPDYSAYRESSFGHGIFEVKNETHALWTWHRNQDMYNSPGDQIYI 524          

Query:   76 DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDH----MRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCG--GSEQEFSFKTPPQK---LPLEFAVAGDLGQTEWTNSTLEH--IGSIDYDVLLLPGDLSYADTH----QPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTG-FKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNE-----------ADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            D D  R PP            + PQQVHI+    DH    + VSWVT  + G   V Y     +  + A G    Y+YF Y+SG IHH TI  LE  T YYY  G   + ++F F TPP+    +P  F + GDLGQT  +N T+ H  +       LL  GDLSYAD +       WD++GR VE  A+ +PW+ T GNHEI+  P I     FK Y  R+ +PY+ SGSTS ++YS + A  ++I+L SY  +   + QY+WL+ +L K++R +TPW++VL+H P YN+   H  EGE+MR   E      +VDVVFAGHVHAYER  RI N              D   P+Y+TIGDGGN EGL  +  EP    S +REPSFGHG L I N THA++GWHRN D  +V  D  WL +
Sbjct:   45 DSDVFRVPP----------GYNAPQQVHITQ--GDHEGKGVIVSWVTPDEPGSKTVLYWAENSELKNSADGFILKYRYFNYTSGYIHHCTIKDLEFDTKYYYEVGIGNTTRQFWFITPPRPGPDVPYTFGLIGDLGQTHDSNRTVTHYELNPTKGQTLLFVGDLSYADDYPFHDNSRWDTWGRFVERSAAYQPWIWTAGNHEIDFVPEIGERKPFKPYTHRYHVPYRASGSTSPMWYSIKRASAYIIVLSSYSAYGKYTPQYKWLEKELPKVNRTETPWLIVLMHCPMYNSYAHHYMEGETMRVMYEPWFVEFKVDVVFAGHVHAYERSERISNVAYNIVNGLCAPIRDQSAPIYITIGDGGNLEGLVTSMTEPQPSYSAFREPSFGHGILDIKNRTHAYFGWHRNQDGYAVEADSVWLHN 453          

Query:  145 PQQVHISLVGK-DHMRVSWVTD----SKHGK-----------SVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKT----PPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPAS-----------------------------------PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASS 1317
            P+Q+ +SL    D + +SW+T     S H K           SVV YG      N +A G    Y   +       Y+SG IHHV +  L+P  +YYYRCG          +SFKT     P+  P   AV GDLG T  T++T+ H+ S    + LL GD++YA                       +T+QP WD +GR ++P  SK P MV +GNHEIE    +    F AY++R+  P +ESGS+S  YYSF   G H +MLG+Y+ +   SDQY+WL+ DLA +DR  TPW+V + H PWY++  AH  E E M  AMEELLY+  VD+VF GHVHAYER  R+YN   DPCGPV++ +GDGGNRE +A+   +EP +                                     S +RE SFGHG L + N+T A W WHRN DS S V DQ ++  +     C     Q+E+  +S
Sbjct:   77 PEQISLSLSATYDSVWISWITGEFQMSNHNKNITPLDPKSVASVVRYGTLRNPLNHEAKGYSLVYSQLYPFEGLQNYTSGIIHHVRLTGLKPDKLYYYRCGDPSIGALSDVYSFKTMPVSSPKTYPKRIAVMGDLGLTYNTSTTISHVISNKPQLALLVGDVTYANLYLTNGTGCDCYSCSFPNSPIHETYQPRWDYWGRFMQPLVSKVPLMVVEGNHEIEKQ--VGNQTFAAYSSRFAFPAKESGSSSTFYYSFNAGGIHFVMLGAYIAYHRSSDQYRWLERDLANVDRFVTPWLVAVWHPPWYSSYNAHYREAECMMAAMEELLYSYAVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIVVGDGGNREKMAVGHADEPGNCPDPATTPDQHIGGFCALNFTTGPAAGQFCWDRQPDYSAFRESSFGHGILEVKNQTWALWTWHRNQDSRSTVGDQIYI--VRQPDKCPVRYKQSERWFAS 554          

Query:  145 PQQVHISLVGKDHMRV--SWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSE--QEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQP-----LWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPT-GFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYN-----------NEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            PQQVHI+    +   V  SWVT  + G S V+YG +   Y+  A G   +Y ++ Y+SG IH   +  LE  T YYY+ G  +  +EF F+TPP+     P +F + GDLGQT  + +TLEH        +L  GDL+YAD +        WD++GR VE  A+ +PWM + GNHEIE  P +     FK+Y  R+  P+  S S+S L+Y+   A  H+I+L SY  F   + Q++WLQ +L ++DR+KTPW++VL+H P YN+N AH  EGESMR   EE   + +VDV+FAGHVHAYER  RI N             AD   PVY+T+GDGGN+EGLA  F +P    S +RE S+GH  L I N THA + W+RN+D   V  D F L +
Sbjct:   63 PQQVHITQGDYNGKAVIISWVTPDEPGTSKVQYGVSKKNYDFTAEGAVRNYTFYNYTSGYIHQCLVDGLEYDTKYYYKIGNGDSYREFWFQTPPKINPDTPYKFGIIGDLGQTYNSLATLEHYMQSGAQAVLFVGDLAYADRYMYNDVGIRWDTWGRFVERSAAYQPWMWSVGNHEIEYMPYLGEVIPFKSYLNRYPTPHLASKSSSPLWYAIRRASAHIIVLSSYSPFVKYTPQWEWLQEELERVDREKTPWLIVLMHVPIYNSNEAHFMEGESMRAVFEEWFVHYKVDVIFAGHVHAYERSYRISNIHYNVSGGDCYPAADESAPVYITVGDGGNQEGLAERFRDPQPDYSAFREASYGHSTLEIKNRTHALYHWNRNDDGKKVPTDAFVLHN 457          

Query:  145 PQQVHISLVGKDHMRV--SWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGG--SEQEFSFKTPPQ---KLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQP-----LWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPT-GFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYN-----------NEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLES 1257
            PQQVHI+    +   V  SWVT  + G + V+YG +  KY+  A G   +Y ++ Y SG IH   +  LE  T YYY+ G   S +EF F+TPP+     P +F + GDLGQT  + STLEH        +L  GDL+YAD ++       WDS+GR VE  A+ +PWM + GNHEIE  P +     FK+Y  R+  P+  S S+S  +Y+   A  H+I+L SY  F   + Q++WL+ +L ++DR+KTPW++VL+H P YN+N AH  EGESMR   E+     +VDVVFAGHVHAYER  R+ N             AD   PVY+T+GDGGN+EGLA  F +P    S +RE S+GH  L I N THA + W+RN+D   V  D F L +
Sbjct:   62 PQQVHITQGDYNGKAVIISWVTPDEPGTNKVQYGVSKKKYDFTAEGTVKNYTFYNYKSGYIHQCLVDGLEYETKYYYKIGSGDSSREFWFQTPPKINPDTPYKFGIIGDLGQTYNSLSTLEHYMQSGAQAVLFVGDLAYADRYKYNDVGIRWDSWGRFVERSAAYQPWMWSAGNHEIEYMPYMGEVIPFKSYLNRYPTPHLASKSSSPFWYAIRRASAHIIVLSSYSSFVKYTPQWEWLREELKRVDREKTPWLIVLMHIPIYNSNEAHFMEGESMRAVFEKWFVRYKVDVVFAGHVHAYERSYRVSNIHYNVSSGDRFPAADESAPVYITVGDGGNQEGLAGRFRDPQPDYSAFREASYGHSTLEIKNRTHAIYHWNRNDDGKKVPTDAFVLHN 456          

Query:  205 DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKT----PPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPAS-----------------------------------PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASS 1317
            D K   SVV YG      N +A G    Y   +       Y+SG IHHV +  L+P  +YYYRCG          +SFKT     P+  P   AV GDLG T  T++T+ H+ S    + LL GD++YA                       +T+QP WD +GR ++P  SK P MV +GNHEIE    +    F AY++R+  P +ESGS+S  YYSF   G H +MLG+Y+ +   SDQY+WL+ DLA +DR  TPW+V + H PWY++  AH  E E M  AMEELLY+  VD+VF GHVHAYER  R+YN   DPCGPV++ +GDGGNRE +A+   +EP +                                     S +RE SFGHG L + N+T A W WHRN DS S V DQ ++  +     C     Q+E+  +S
Sbjct:  129 DPKSVASVVRYGTLRNPLNHEAKGYSLVYSQLYPFEGLQNYTSGIIHHVRLTGLKPDKLYYYRCGDPSIGALSDVYSFKTMPVSSPKTYPKRIAVMGDLGLTYNTSTTISHVISNKPQLALLVGDVTYANLYLTNGTGCDCYSCSFPNSPIHETYQPRWDYWGRFMQPLVSKVPLMVVEGNHEIEKQ--VGNQTFAAYSSRFAFPAKESGSSSTFYYSFNAGGIHFVMLGAYIAYHRSSDQYRWLERDLANVDRFVTPWLVAVWHPPWYSSYNAHYREAECMMAAMEELLYSYAVDIVFNGHVHAYERSNRVYNYTLDPCGPVHIVVGDGGNREKMAVGHADEPGNCPDPATTPDQHIGGFCALNFTTGPAAGQFCWDRQPDYSAFRESSFGHGILEVKNQTWALWTWHRNQDSRSTVGDQIYI--VRQPDKCPVRYKQSERWFAS 570          

Query:    1 MKKLCLPVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            M+KL L V SL L+ICL PQL+K+QDDD++RQPPR VIFT HT SD DPQQVHISLVGKDHMRVSWVT+SKH KS+VEYGK  G YN KATGE TSYKYF YSSGKIHHVTIGPLEPAT Y+YRCGGS  EFSFKTPPQKLPLEFAVAGDLGQTEWTNSTL+HIGS+DYDVLL PGDLSYADT QPLWDSFGRIVEPYASKRPWMVT+GNHE+ES PII PTGFKAYNARW MPYQESGSTSNLYYSFEVAGTHVIMLGSY +FDA+SDQY+WLQADLAKID K TPW+VVLLHAPWYNTN+AH+GEGESMR+AMEELLYNARVDVVFAGHVHAYERFTR+YNNEADPCGPVYMTIGDGGNREGLAL FE PASPLSLYREPSFGHGRLR++NETHAFWGWHRNN+SNSVVKDQ WLESLSSSKTC+KS +Q  K+ SSSVNDEL
Sbjct:    1 MEKLYLHVFSLLLVICLFPQLIKSQDDDYVRQPPRGVIFTHHTSSDEDPQQVHISLVGKDHMRVSWVTESKHVKSIVEYGKESGMYNGKATGEHTSYKYFLYSSGKIHHVTIGPLEPATTYFYRCGGSGPEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLQHIGSMDYDVLLXPGDLSYADTQQPLWDSFGRIVEPYASKRPWMVTEGNHEVESIPIINPTGFKAYNARWPMPYQESGSTSNLYYSFEVAGTHVIMLGSYADFDAKSDQYKWLQADLAKIDXKVTPWIVVLLHAPWYNTNSAHKGEGESMRKAMEELLYNARVDVVFAGHVHAYERFTRVYNNEADPCGPVYMTIGDGGNREGLALKFENPASPLSLYREPSFGHGRLRVLNETHAFWGWHRNNESNSVVKDQVWLESLSSSKTCMKSGSQ--KVGSSSVNDEL 443          

Query:  427 LEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            +   V+GDLGQTEWT STL+HIG +DYDVLLLPGDLSYA++ QPLWDSFGRIVEPYASKRPWMVT+GNHEIE+FP     G  AYNARW+MPYQESGSTSNLYYSFEV GTHVIMLGSY EFDAESDQY+WLQADLAKIDRK TPWVVVLLHAPWYNTNTAH+GEGESMRQAMEELLY ARVDVVFAGHVHAYERFTR+YNNEADPCGPVYMT+GDGGNREGLAL FE+PASPLSLYREPSFGHGRLRIVNETHAFWGWHRNN SNSVVKDQ WLESLSSSK CL   NQ  K+ SSSVNDEL
Sbjct:   15 IHVVVSGDLGQTEWTKSTLQHIGGMDYDVLLLPGDLSYANSLQPLWDSFGRIVEPYASKRPWMVTEGNHEIENFP----PGXMAYNARWQMPYQESGSTSNLYYSFEVVGTHVIMLGSYAEFDAESDQYKWLQADLAKIDRKVTPWVVVLLHAPWYNTNTAHKGEGESMRQAMEELLYKARVDVVFAGHVHAYERFTRVYNNEADPCGPVYMTVGDGGNREGLALMFEDPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNXSNSVVKDQLWLESLSSSKACLHPGNQ--KVGSSSVNDEL 311          

Query:   82 DFIRQPPRRVI-FTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            +++R PPR+ + F    +S S PQQVH+SL G +HMRV+WVTD K   SVVEYG + G  +S A GE TSY Y  YSSGKIHH  IGPLE  T+Y+Y+CGG   EF FKTPP + P+ FAV GDLGQT WT STL+HI    YDV LLPGDLSYAD  Q  WD+FG +V+P AS RPWMVTQGNHE E+ P++   GF++YN+RW+MPY+ES S+SNLYYSFE AG H IMLGSY ++D  SDQY+WL+ADL+K+DR+KTPW++VL H PWYN+N AHQGEG+SM  AME LLY A VD VFAGHVHAYER  R+    +D CG V++TIGDGGNREGLA  ++ P+   S++RE SFGHG L I N THA W WHRN+D   V  DQ W+ SL S     +  ++  K+
Sbjct:   22 EYLRPPPRKALHFPWSRKSSSLPQQVHVSLAGDEHMRVTWVTDDKSAPSVVEYGTSSGTXSSVAXGESTSYTYMLYSSGKIHHTVIGPLEHDTVYFYQCGGQGPEFXFKTPPAQFPITFAVXGDLGQTGWTKSTLDHIDQCKYDVHLLPGDLSYADYIQSRWDTFGELVQPLASARPWMVTQGNHEKENIPLL-KDGFQSYNSRWKMPYEESXSSSNLYYSFEXAGVHAIMLGSYTDYDEYSDQYRWLKADLSKVDRQKTPWLLVLFHVPWYNSNKAHQGEGDSMMAAMEPLLYAASVDXVFAGHVHAYERTKRVNKGRSDTCGAVHITIGDGGNREGLAHKYKSPSPEWSVFREASFGHGELNIKNSTHALWTWHRNDDDEPVRSDQVWITSLVSXGCVAEKRHEQRKI 430          

Query:   19 PVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSD-PQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSS 1269
            P++++  +I  S  ++ AQ+  ++R PPR+ +    +R  S  PQQVHIS  G  H RV+WVTD K   SVVEYG + GKY+S             Y SGKIHH   GPLE  T+Y+Y+CGG   EF FKTPP + P+ FAVAGDLGQT WT STL+HI    YDV LLPGDLSYAD  Q  WD+FG +V+P AS RPWMVTQGNHE E+ P++   GF++YN+RW+MPY+ESGS+SNLYYSFEVAG H IMLGSY + D  SDQY+WL+ADL+K+DR+KTPW +VL H PWYN+N AHQGEG SM   ME LLY A  D+VFAGHVH YER  R+ N ++D CG V++TIGDGGN+EGLA  ++      S++RE SFGHG L IVN THAFW WHRN+D   V  DQ W+ SL SS
Sbjct:  376 PIITVLFLI--SATVIAAQE--YVRPPPRKALHFPWSRKPSSLPQQVHISFAGDKHXRVTWVTDDKSAPSVVEYGTSSGKYSS-----------MLYXSGKIHHTVXGPLEHDTVYFYQCGGQAPEFQFKTPPAQFPITFAVAGDLGQTGWTKSTLDHIDQCKYDVHLLPGDLSYADYIQSRWDTFGELVQPLASARPWMVTQGNHEKENIPLL-KDGFQSYNSRWKMPYEESGSSSNLYYSFEVAGVHAIMLGSYTDXDEYSDQYRWLKADLSKVDRQKTPWXLVLFHVPWYNSNKAHQGEGXSMMAXMEPLLYAASADIVFAGHVHXYERTKRVNNGKSDRCGAVHITIGDGGNKEGLAHKYKNXPPEWSVFREASFGHGELNIVNSTHAFWTWHRNDDXEPVRSDQVWITSLVSS 777          

Query:   64 LKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVT-DSKHGKSV-----------VEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKTPPQK----LPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA------------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEE--------------------------PAS---------PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDS 1221
            L+   DD     PR     K   + + P+Q+ +++     M VSWVT D++ GK+V           V YG+  GKY S   G    Y   +       Y+S  IHHV I  L+P T YYY+CG S      QE + +T P+      P   AV GDLG T  T++T++H+   D  ++L+ GDL YA                        +T+QP WD +GR +EP  S+ P MV +GNHEIE  P +    F++Y  R+ +P +E GS SN YYSF+  G H IMLG+Y++++A   QY WL+ DL ++DR  TPW+V   H PWYN+ ++H  E E MRQ ME LLY   VD+VF+GHVHAYER  R+YN   DPCGP+Y+T+GDGGN E + + F +                          PA            S +RE SFGHG L +VN T+A W WHRN D+
Sbjct:   86 LRRGSDDLPMDHPR----LKKKVTSNFPEQIALAISSPTAMWVSWVTGDAQIGKTVRPLDPSTVGSEVRYGEESGKYTSVKKGVSVVYSQLYPFAGLLNYTSAIIHHVRIDGLKPGTKYYYKCGDSSIPAMSQEHALETLPEPGENTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 552          

Query:  445 GDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGES--MRQAMEELLYNARVDVVFAGHVHAYERF 1014
            GDLGQTEWT+STLEHI   ++D+ LLPGDLSYAD  Q  WDSFGR+V+P ASKRPWMVTQGNHEIE  PI++   F AYNARW MPY++SGS SNLYYSF VAG HVIMLGSY +FD  S QYQWLQADL K+DR +TPW+VVL+HAPWYN+N AHQGE ES  M++AME+LLY ARVDVV+AGHVHAYERF
Sbjct:    4 GDLGQTEWTSSTLEHIDKANHDMFLLPGDLSYADLIQNKWDSFGRLVQPLASKRPWMVTQGNHEIEKIPIVHSHAFTAYNARWHMPYEQSGSDSNLYYSFNVAGVHVIMLGSYTDFDPSSAQYQWLQADLGKVDRGRTPWIVVLIHAPWYNSNKAHQGESESVDMKEAMEDLLYQARVDVVYAGHVHAYERF 195          

Query:  142 DPQQVHISLVGK-DHMRVSWVT------------DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFK---------TPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPA-------------------------------------SPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWL 1251
            +P+Q+ +SL    D + +SW+T            D K   SVV YGK       +ATG    Y   +       Y+SG IHHV +  L+P T+Y+YRCG        K         + P+  P   AV GDLG T  T +T+ H+ S + D++LL GD++YA                       +T+QP WD +GR ++   SK P MV +GNHEIE         F+AY++R+  P +ESGS+S  YYSF   G H IMLG+Y +F     QY+WL+ DLA +DR  TPW+    H PWY+T  AH  E E MR  MEELLY+  VD+VF GHVHAYER  R+Y+   DPCGPVY+T+GDGGNRE +A+   +EP                                         S +RE SFGHG L + NET A W W+RN DS++ + DQ ++
Sbjct:   74 EPEQISVSLSADYDSVWISWITGEYQIGDKIKPLDPKSVASVVRYGKLRYPPTHEATGYSLVYNQLYPFEGLQNYTSGIIHHVRLTGLKPNTLYFYRCGDPSIPAMSKIHHYRTMPVSGPRSYPERIAVVGDLGLTYNTTTTISHLTSNNPDLVLLIGDVTYANLYLTNGTGSDCYSCSFPNSPIHETYQPRWDYWGRYMQSLVSKVPIMVVEGNHEIEEQA--ENKTFEAYSSRFAFPSEESGSSSTFYYSFNAGGIHFIMLGAYTDFSKSGKQYKWLEQDLANVDRSTTPWLAATWHPPWYSTYEAHYREAECMRLEMEELLYSYGVDIVFNGHVHAYERSNRVYDYNLDPCGPVYLTVGDGGNREKMAVQHADEPGRCPEPSTTPDQHLGDGAFCAENFTSGPAAGKFCWDXQPDYSAFRESSFGHGILEVKNETWALWTWYRNQDSDNKIGDQIYI 531          

Query:  142 DPQQVHISLVGK-DHMRVSWVT------------DSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFF-------YSSGKIHHVTIGPLEPATMYYYRCGGSE-----QEFSFKTPP----QKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA-----------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTF-EEPA---SPL----------------------------------SLYREPSFGHG--------------------------------------RLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDE 1332
            +P+Q+ +SL    D + +SW+T            D K  +SVV+YG       ++A+G    Y   +       Y+SG IHHV +  L+P T+Y+Y+CG        +   F+T P    +  P   AV GDLG T  T +T+ H+ S + D++LL GD++YA                       +T+QP WD +GR ++   SK P MV +GNHEIE         F+AY++R+  P +ESGS+S  YYSF   G H IM+G+Y +F     QY+WL+ DLA +DR  TPW+V   H PWY+T  AH  E E MR  MEELLY+  VD+VF+GHVHAYER  R+Y+   DPCGPVY+T+GDGGNRE +A+   +EP     PL                                  S +RE SFGHG                                       L++ NET A W W+RN DS+  + DQ ++  +      +++ ++ E+  S+S N E
Sbjct:   74 EPEQISVSLSADYDSVWISWITGEYQIGDNIMPLDPKSVQSVVQYGXLGYPPTNEASGYSLVYNQLYPFEGLQNYTSGIIHHVRLTGLKPNTVYFYQCGDPSIPXMSEIHHFRTMPVTGPRSYPERIAVVGDLGLTYNTTATIXHLTSNNPDLVLLIGDVTYANLYLTNGTGSDCYSCSFPNSPIHETYQPRWDYWGRYMQSLVSKVPIMVVEGNHEIEEQA--ENKTFEAYSSRFAFPSEESGSSSTFYYSFNAGGIHFIMIGAYTDFSKSGKQYKWLEQDLANVDRSITPWLVATWHPPWYSTYEAHYREAECMRMEMEELLYSYGVDIVFSGHVHAYERSNRVYDYNLDPCGPVYLTVGDGGNREKMAVHHADEPGHCPEPLTTPDEHLGAGAFCAMNFTSGPAAGKFCWDRQPDYSAFRESSFGHGILELTYRPRLQSAENVYTRMTAQFNHLDYIXTVGFNVHNLQVKNETWALWTWYRNQDSDDKIGDQIYIIGIGRK---VQNESKQEQKKSNSANVE 593          

Query:  343 LEPATMYYYRCGGSE-----QEFSFKTPPQK----LPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYA------------------------DTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEE--------------------------PAS---------PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDS 1221
            L+P T YYY+CG S      QE + +T P+      P   AV GDLG T  T++T++H+   D  ++L+ GDL YA                        +T+QP WD +GR +EP  S+ P MV +GNHEIE  P +    F++Y  R+ +P +E GS SN YYSF+  G H IMLG+Y++++A   QY WL+ DL ++DR  TPW+V   H PWYN+ ++H  E E MRQ ME LLY   VD+VF+GHVHAYER  R+YN   DPCGP+Y+T+GDGGN E + + F +                          PA            S +RE SFGHG L +VN T+A W WHRN D+
Sbjct:  165 LKPGTKYYYKCGDSSIPAMSQEHALETLPEPGXNTYPRRIAVVGDLGLTSNTSTTIDHLIQNDPSMILMVGDLCYANQYRTTGGKGASCFSCAFPDAPIRETYQPRWDGWGRFMEPLTSRVPMMVIEGNHEIE--PQVSGITFESYLTRFAVPSEEXGSKSNFYYSFDAGGVHFIMLGAYIDYNATGAQYAWLKDDLHRVDRTVTPWLVAAWHPPWYNSYSSHYQEFECMRQEMEALLYQYGVDIVFSGHVHAYERMNRVYNYTLDPCGPLYITVGDGGNIEEVDVDFADDPGKCPSAGDNTPEFGGVCHLNFSSGPAKGNFCWSKQPEWSAFRESSFGHGILEVVNSTYALWTWHRNQDT 523          

Query:   88 IRQPPRRVIFTKHTRSDSDP-----QQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQ 825
            +R   RR      T S   P     + +  S  G  H RV+WVTD K   SVVEYG + GKY                   KIHH   GPLE  T+Y+Y+CGG   EF FKTPP + P+ FAVAGDLGQT WT STL+HI    YDV LLPGDLSYAD  Q  WD+FG +V+P AS RPWMVTQGNHE E+ P++   GF++YN+RW+MPY+ESGS+SNLYYSFEVAG H IMLGSY + D  SDQY+WL+
Sbjct:   22 LRHRHRRPRIRPTTASQGPPFPMESKTLFASPAGDKHXRVTWVTDDKSAPSVVEYGTSSGKYR------------------KIHHTVXGPLEHDTVYFYQCGGQAPEFQFKTPPAQFPITFAVAGDLGQTGWTKSTLDHIDQCKYDVHLLPGDLSYADYIQSRWDTFGELVQPLASARPWMVTQGNHEKENIPLL-KDGFQSYNSRWKMPYEESGSSSNLYYSFEVAGVHAIMLGSYTDXDEYSDQYRWLK 253          

Query:  736 YSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNN 1215
            YS+E   + +I + +             L ADL+K+DR+KTPW++VL H PWYN+N AHQGEG SM  AME LLY A  D+VFAGHVHAYER  R+ N ++D CG V++TIGDGGN+EGLA  ++      S++RE SFGH + +     HA   WH+ N
Sbjct:  316 YSYEALASRIITITAN------------LDADLSKVDRQKTPWLLVLFHVPWYNSNKAHQGEGNSMMAAMEPLLYAASADIVFAGHVHAYERTKRVNNGKSDRCGAVHITIGDGGNKEGLAHKYKNSPPEWSVFREASFGHAKSK-----HA--KWHKAN 456          

Query:    7 KLCLPVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQN 1299
            K  + +L L  I+CL  Q+     + F RQP R++IFT H RSDSDPQQVHISLVG DHMRVSW+TD KH +SVVEYG   G+Y++KATGE TSY YF Y SGKIHHV IGPL+P T+YYYRCGGS  EFSFKTPP KLP+EF V GDLGQTEWT STL+H+ S DYDV LLPGDLSYADTHQPLWDSFGR+VEPYAS+ PWMVT+GNHEIE+FPII P GFKAYNARW MPY+ESGSTSNLYYSF+VA THVIMLGSY +FDA S QY WLQ+DLAKIDRK+TPWV+ LLHAPWYNTN AHQGEGE MRQAMEELLY ARVD+VFAGHVHAYERFTRIY+N+AD CGP+Y+TIGDGGNREGLAL+F++P SPLSLYREPSFGHGRLRIVNETHA+W WHRNND+++ V D  W+ESLS+SK C  +  Q+
Sbjct:    6 KSLVVILLLLHILCLQSQV-----NGFSRQPSRQLIFTPHKRSDSDPQQVHISLVGNDHMRVSWITDDKHSESVVEYGTKKGEYSTKATGEHTSYHYFLYESGKIHHVVIGPLQPNTIYYYRCGGSGSEFSFKTPPLKLPIEFVVVGDLGQTEWTTSTLKHVDSKDYDVFLLPGDLSYADTHQPLWDSFGRLVEPYASRIPWMVTEGNHEIETFPIIQPNGFKAYNARWPMPYKESGSTSNLYYSFDVASTHVIMLGSYTDFDAHSQQYTWLQSDLAKIDRKRTPWVIALLHAPWYNTNEAHQGEGEDMRQAMEELLYEARVDLVFAGHVHAYERFTRIYDNKADSCGPLYVTIGDGGNREGLALSFKKPPSPLSLYREPSFGHGRLRIVNETHAYWSWHRNNDTDTFVADGVWIESLSNSKACWNAQGQH 431          

Query:    1 MKKLCLPVLSLFLIICLSPQLLKAQ-DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPAS-PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEK--MASSSVNDEL 1335
            M+K  L V    L I  S QL ++    D+ RQPPRR+IFT H RSDSDPQQVHISLVG+D M+VSW+TD K  +S+VEYGK PGKY + ATGE TSY YFFYSSGKIHHV IGPLE  T+YYYRCGGS QEF FKTPP   P+EFAV GDLGQTEWT STL H+   +YDVLLLPGDLSYAD+HQPLWD FGR+VEPYAS RPWMVT+GNHEIE FPIIYP GFKA+N+RW MP+QESGSTSNLYYSFEVAG HVIMLGSY EFD +S QY+WL+ DL K+DR++TPW++VL+HAPWYNTN AH+GEGESMR+AME+LLY ARVDVVFAGHVHAYERFTR+Y N+AD CGP+++TIGDGGNREGLALTFE+P S  LS+YREPSFGHGRLRI+N+THAFW WHRNNDS+ ++ D  WL+SLS S+ C +         + S ++NDEL
Sbjct:   75 MEKSWLTVSFHLLTILSSIQLPRSHASSDYSRQPPRRLIFTPHHRSDSDPQQVHISLVGRDRMKVSWITDDKSARSIVEYGKMPGKYEASATGEHTSYNYFFYSSGKIHHVEIGPLEAGTVYYYRCGGSGQEFYFKTPPSSFPIEFAVVGDLGQTEWTASTLTHVNRTNYDVLLLPGDLSYADSHQPLWDCFGRLVEPYASHRPWMVTEGNHEIEIFPIIYPDGFKAFNSRWPMPFQESGSTSNLYYSFEVAGCHVIMLGSYAEFDEKSAQYKWLKGDLGKVDRRRTPWLIVLIHAPWYNTNLAHKGEGESMRKAMEKLLYEARVDVVFAGHVHAYERFTRVYKNKADECGPIHVTIGDGGNREGLALTFEKPTSASLSVYREPSFGHGRLRILNQTHAFWSWHRNNDSDCILADSLWLQSLSVSRQCTQFQQDQASLPLVSVNLNDEL 523          

Query:    1 MKKLCLPVLSLFLIICLSPQLLKAQ-DDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPAS-PLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEK--MASSSVNDEL 1335
            M+K  L V    L I  S QL ++    D+ RQPPRR+IFT H RSDSDPQQVHISLVG+D M+VSW+TD K  +S+VEYGK PGKY + ATGE TSY YFFYSSGKIHHV IGPLE  T+YYYRCGGS QEF FKTPP   P+EFAV GDLGQTEWT STL H+   +YDVLLLPGDLSYAD+HQPLWD FGR+VEPYAS RPWMVT+GNHEIE FPIIYP GFKA+N+RW MP+QESGSTSNLYYSFEVAG HVIMLGSY EFD +S QY+WL+ DL K+DR++TPW++VL+HAPWYNTN AH+GEGESMR+AME+LLY ARVDVVFAGHVHAYERFTR+Y N+AD CGP+++TIGDGGNREGLALTFE+P S  LS+YREPSFGHGRLRI+N+THAFW WHRNNDS+ ++ D  WL+SLS S+ C +         + S ++NDEL
Sbjct:    1 MEKSWLTVSFHLLTILSSIQLPRSHASSDYSRQPPRRLIFTPHHRSDSDPQQVHISLVGRDRMKVSWITDDKSARSIVEYGKMPGKYEASATGEHTSYNYFFYSSGKIHHVEIGPLEAGTVYYYRCGGSGQEFYFKTPPSSFPIEFAVVGDLGQTEWTASTLTHVNRTNYDVLLLPGDLSYADSHQPLWDCFGRLVEPYASHRPWMVTEGNHEIEIFPIIYPDGFKAFNSRWPMPFQESGSTSNLYYSFEVAGCHVIMLGSYAEFDEKSAQYKWLKGDLGKVDRRRTPWLIVLIHAPWYNTNLAHKGEGESMRKAMEKLLYEARVDVVFAGHVHAYERFTRVYKNKADECGPIHVTIGDGGNREGLALTFEKPTSASLSVYREPSFGHGRLRILNQTHAFWSWHRNNDSDCILADSLWLQSLSVSRQCTQFQQDQASLPLVSVNLNDEL 449          

Query:   10 LCLPVLSL-FLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQ 1296
            +  P+L L  L   L  Q L +Q+++F+RQP  ++I T H RS SDPQQVHISLVG++ MRVSW+T+ KH +SVVEYG   G+Y++KATG  TSY+YFFY+SGKIH+V IGPL+P + Y+YRCGGS  EFSFKTPP + P+EF + GDLGQTEWT STL+HI S DYDV LLPGDLSYAD+ QPLWDSFGR+VEPYASKRPWMVT+GNHEIE FPIIYP GF+AYNARW MP+Q+SGSTSNLYYSFEVAGTHVIMLGSY +FD++S QY WLQ+DLA IDR KTPWV+VLLHAPWYNTN AHQGEGESMRQAMEELLY ARVD+VFAGHVHAYERFTRIY+N+AD CGP+Y+TIGDGGNREGLAL F+ P+SPLSLYREPSFGHGRLRI+NETHA W WHRNND+++VV D  W+ESLSSSK C K+  Q
Sbjct:   31 MAFPILLLRTLCFLLFSQPLLSQENNFVRQPAAQLIITPHHRSHSDPQQVHISLVGQEKMRVSWITEDKHAESVVEYGTKAGEYSAKATGVYTSYQYFFYNSGKIHNVVIGPLQPGSTYFYRCGGSGPEFSFKTPPPRCPIEFVIVGDLGQTEWTASTLKHIDSSDYDVFLLPGDLSYADSQQPLWDSFGRLVEPYASKRPWMVTEGNHEIEIFPIIYPQGFQAYNARWPMPFQQSGSTSNLYYSFEVAGTHVIMLGSYTDFDSQSLQYTWLQSDLANIDRVKTPWVIVLLHAPWYNTNEAHQGEGESMRQAMEELLYEARVDLVFAGHVHAYERFTRIYDNKADSCGPMYVTIGDGGNREGLALMFKNPSSPLSLYREPSFGHGRLRILNETHAHWSWHRNNDADAVVADGVWIESLSSSKACSKTPYQ 460          

Query:   34 FLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            F ++  + Q   ++D+ + R P R +IFT H   +S+ QQVH+SLVG+DHMRV+W+TD KH  S VEYGK PG YN+ ATG+ TSY+YFFYSSGKIHHV IGPLEP T YYYRCGGS  E SFKTPP  LPLEF V GDLGQT WTNSTL H+ S DYDVLLLPGDLSYADT+QPLWDSFGR+VE YAS+RPWMVT+GNHE E FPII P GFKAYNARW MPY+ES S+SNLYYSF V GTHVIMLGSY +FD  S QY+WL+ADL  IDRKKTPWV+VLLHAPWYNTN AHQGEGESMR+AMEELLY ARVDVVFAGHVHAYERF RIY+N+ DPCGPVY+TIGDGGNREGLALTF+ PASPLSLYRE SFGHGRLRI++ET A W WHRNNDSNS   D+ WL+S+S+S  C  +++  ++      NDEL
Sbjct:   14 FFLLQFTSQCYASKDESYSRPPARNIIFTAHHGLESEAQQVHVSLVGRDHMRVTWITDDKHAPSTVEYGKQPGTYNAMATGDHTSYRYFFYSSGKIHHVKIGPLEPGTTYYYRCGGSGPELSFKTPPATLPLEFVVIGDLGQTGWTNSTLAHVNSRDYDVLLLPGDLSYADTNQPLWDSFGRLVEKYASQRPWMVTEGNHETEIFPIIQPHGFKAYNARWLMPYEESNSSSNLYYSFNVVGTHVIMLGSYTDFDEHSQQYKWLEADLGSIDRKKTPWVIVLLHAPWYNTNNAHQGEGESMRKAMEELLYKARVDVVFAGHVHAYERFARIYDNKVDPCGPVYITIGDGGNREGLALTFQNPASPLSLYREASFGHGRLRIMDETRAHWSWHRNNDSNSFSADEVWLDSISTSTACW-AIDDEKEPPKFIANDEL 446          

Query:   19 PVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQ 1296
            P+L   +   L PQ L +Q+++F+RQP  ++I T H RS+S+PQQVHISLVGKD MRVSW+T+ K  +++VEYG   G+Y+ K  GE TSY+YFFY+SGKIH+  IGPLEP T Y+YRCGG   EFSFKTPP K P+EF + GDLGQTEWT STL+H+   DYDV L+PGDLSYAD+ QPLWDSFGR+VEPYASKRPWMVT+GNHEIE FPIIYP GF+AYN RW MP+QESGS SNLYYSFEVAG H+IMLGSY +F  ES QY+WLQ DL KIDR KTPWV+ ++HAPWY TN AHQGEGESMRQAMEELL+ ARVD+VFAGHVHAYERFTRIYNN+AD CGP+Y+TIGDGGNREGLAL F+ P SPLSL+REPSFGHGRLRI+NETHA W WHRNND +++V D  W+ESLS+ K C ++ NQ
Sbjct:   12 PILLQTICFLLFPQPLMSQENNFVRQPASQLIITPHQRSNSEPQQVHISLVGKDKMRVSWITEDKETETMVEYGTKAGEYSEKTMGEHTSYQYFFYNSGKIHNAVIGPLEPNTTYFYRCGGLGPEFSFKTPPSKFPIEFVIVGDLGQTEWTASTLKHVDKSDYDVFLIPGDLSYADSQQPLWDSFGRLVEPYASKRPWMVTEGNHEIEIFPIIYPKGFEAYNTRWPMPFQESGSNSNLYYSFEVAGVHIIMLGSYADFSVESQQYEWLQLDLTKIDRVKTPWVITMVHAPWYTTNEAHQGEGESMRQAMEELLFKARVDLVFAGHVHAYERFTRIYNNKADSCGPMYVTIGDGGNREGLALRFKNPPSPLSLFREPSFGHGRLRILNETHAHWSWHRNNDKDAIVADGIWIESLSNLKACSETPNQ 437          

Query:   34 FLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            F ++ L P + +A   +  RQPPR ++F  + RS SDPQQVHISL GKDHMRV+++T+    +SVVEYGK PGKY+ KATGE TSYKYFFY SGKIHHV IGPL+  T YYYRCGG+  EFSFKTPP   P+EFA+ GDLGQTEWT +TL HI S DYDV LLPGDLSYADTHQPLWDSFGR+VEP ASKRPWMVT+GNHEIE FPII  T FK+YNARW MP+ ES STSNLYYSF+VAG H +MLGSY +FD ESDQYQWLQADLAK+DRK TPWVVVLLHAPWYNTN AH+GEGESMR+AME LL+NARVDVVF+GHVHAYERF R+YNN+ADPCGP+++TIGDGGNREGLAL+F++P SPLS +RE SFGHGRL++++   A W WHRNNDSNS++ D+ WL+SLS+S +C  S   N+++
Sbjct:   10 FTLLFLCPFISQADVPELSRQPPRPIVFVHNDRSKSDPQQVHISLAGKDHMRVTFITEDNKVESVVEYGKQPGKYDGKATGECTSYKYFFYKSGKIHHVKIGPLQANTTYYYRCGGNGPEFSFKTPPSTFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYADTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPLSEFRESSFGHGRLKVMDGKRAHWSWHRNNDSNSLLADEVWLDSLSTSSSCWPSSRSNDEL 434          

Query:    1 MKKLCLPVLSLFLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            MK L L  LS F ++ L P + +A   +  R+PPR ++F  + RS  DPQQVH+SL GKDHMRV+++T+    +SVVEYGK PGKY+ KATGE TSYKY FY SGKIHHV IGPL+P T YYYRCGG+  EFSFKTPP   P+EFA+ GDLGQTEWT +TL  I S DYDV LLPGDLSYADT QPLWDSFGR+VEP AS+RPWMVT+GNHEIE FPI   T FK+YNARW MP+ ES S SNLYYSF+VAG H +MLGSY +FD++SDQYQWLQADLAK+DRK TPWVVVLLHAPWYNTN AH+GEGESMR AME LL++ARVDVVF+GHVHAYERF R+YNN+ADPCGP+Y+TIGDGGNREGLAL+F++P SPLS YRE SFGHGRL++++   A W WHRNNDSNS++ D+ WLESLS+S +C  S   ++++
Sbjct:    1 MKLLGLFFLS-FTLLFLCPFISQADVPERSREPPRPIVFVHNDRSKFDPQQVHVSLAGKDHMRVTFITEDNKVESVVEYGKQPGKYDGKATGECTSYKYIFYKSGKIHHVKIGPLQPNTTYYYRCGGNGPEFSFKTPPSTFPVEFAIVGDLGQTEWTAATLSQIKSQDYDVFLLPGDLSYADTSQPLWDSFGRLVEPLASQRPWMVTEGNHEIEFFPIFEHTTFKSYNARWLMPHTESLSDSNLYYSFDVAGVHTVMLGSYTDFDSDSDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMRVAMECLLFSARVDVVFSGHVHAYERFKRVYNNKADPCGPIYITIGDGGNREGLALSFKKPPSPLSEYRESSFGHGRLKVMDGKRAHWSWHRNNDSNSLLADEVWLESLSTSSSCWPSSRSSDEL 435          

Query:   34 FLIICLSPQLLKAQDDDFIRQPPRRVIFTKHTRSDSDPQQVHISLVGKDHMRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKM 1308
            F ++ L P + +A   +  RQPPR ++F  + RS SDPQQ        DHMRV+++T+    +SVVEYGK PGKY+ KATGE TSYKYFFY SGKIHHV IGPL+  T YYYRCGG+  EFSFKTPP   P+EFA+ GDLGQTEWT +TL HI S DYDV LLPGDLSYADTHQPLWDSFGR+VEP ASKRPWMVT+GNHEIE FPII  T FK+YNARW MP+ ES STSNLYYSF+VAG H +MLGSY +FD ESDQYQWLQADLAK+DRK TPWVVVLLHAPWYNTN AH+GEGESMR+AME LL+NARVDVVF+GHVHAYERF R+YNN+ADPCGP+++TIGDGGNREGLAL+F++P SPLS +RE SFGHGRL++++   A W WHRNNDSNS++ D+ WL+SLS+S +C  S   N+++
Sbjct:   10 FTLLFLCPFISQADVPELSRQPPRPIVFVHNDRSKSDPQQ--------DHMRVTFITEDNKVESVVEYGKQPGKYDGKATGECTSYKYFFYKSGKIHHVKIGPLQANTTYYYRCGGNGPEFSFKTPPSTFPVEFAIVGDLGQTEWTAATLSHINSQDYDVFLLPGDLSYADTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPHTESFSTSNLYYSFDVAGVHTVMLGSYTDFDCESDQYQWLQADLAKVDRKTTPWVVVLLHAPWYNTNEAHEGEGESMREAMESLLFNARVDVVFSGHVHAYERFKRVYNNKADPCGPIHITIGDGGNREGLALSFKKPPSPLSEFRESSFGHGRLKVMDGKRAHWSWHRNNDSNSLLADEVWLDSLSTSSSCWPSSRSNDEL 426          

Query:  184 MRVSWVTDSKHGKSVVEYGKAPGKYNSKATGEDTSYKYFFYSSGKIHHVTIGPLEPATMYYYRCGGSEQEFSFKTPPQKLPLEFAVAGDLGQTEWTNSTLEHIGSIDYDVLLLPGDLSYADTHQPLWDSFGRIVEPYASKRPWMVTQGNHEIESFPIIYPTGFKAYNARWRMPYQESGSTSNLYYSFEVAGTHVIMLGSYVEFDAESDQYQWLQADLAKIDRKKTPWVVVLLHAPWYNTNTAHQGEGESMRQAMEELLYNARVDVVFAGHVHAYERFTRIYNNEADPCGPVYMTIGDGGNREGLALTFEEPASPLSLYREPSFGHGRLRIVNETHAFWGWHRNNDSNSVVKDQFWLESLSSSKTCLKSVNQNEKMASSSVNDEL 1335
            MRVSW+T+ KH +SVVEYG   G+Y  KATG  TSY+YF Y+SGKIH+V IGPL+P T Y+YRCGGS  +FSFKTPP K P+EF + GDLGQTEWT STL+H+ S DYDV LLPGDLSYAD+ QPLWDSFGR+VEPYASKRPWMVT+GNHEIESFPIIYP GF+AYNARW MP+Q+SGSTSNLYYSFEV  TH IMLGSY +FDA+S QY WLQ+DLA IDR KTPWV+VLLHAPWYNTN AHQGEGESMRQAMEELLY ARVD+VFAGHVHAYERFTRIY+N+AD CGP+Y+TIGDGGNREGLAL F+ P SPLSLYREPSFGHGRLRI+NETHA W WHRNND+++VV D  W+ESLSSSK C K+ +Q +     + N+EL
Sbjct:    1 MRVSWITEDKHTESVVEYGTKAGEYREKATGLHTSYQYFLYNSGKIHNVVIGPLQPGTTYFYRCGGSGPDFSFKTPPPKFPIEFVIVGDLGQTEWTASTLKHVDSNDYDVFLLPGDLSYADSQQPLWDSFGRLVEPYASKRPWMVTEGNHEIESFPIIYPQGFQAYNARWPMPFQQSGSTSNLYYSFEVTATHFIMLGSYTDFDAQSQQYTWLQSDLANIDRAKTPWVIVLLHAPWYNTNEAHQGEGESMRQAMEELLYEARVDLVFAGHVHAYERFTRIYDNKADSCGPMYVTIGDGGNREGLALMFKNPPSPLSLYREPSFGHGRLRILNETHAHWSWHRNNDADAVVADGVWIESLSSSKACSKTPDQQD-----AANEEL 379