ppa015027m, ppa015027m (mRNA) Prunus persica

Query:  289 SVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISC------YYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            S+LK C     +  GK+IH  ++  G  ++I +  SL+ +Y  C++F  A  +F  +    D+  WN +++       + +  + +KA+ELFE+M+ SGF P+SVTLTTVISSCARL DLERG +IH EL++    LD FV+SALVDMYGKCGCL+MAKEVFEQI  KNVV+WNSMIA YS+ GDS SCI+ FRRM+ EG  PTLTT SSIL+ACSRS  L  GKFIH ++IRN +EADI++ SSLIDLYF  G++ SA+NVF+ MPKTN VSWNVMISGYVKVG Y  AL I+ DM++AGV+P+AIT TS+L ACSQLA LEKGKEIH  +I+S+ E NE++   +    AK                 D V++ ++++A                                   CSH GLVDEGC++FNQMI  YG KP +EHYSCLIDLLGR GRL EAYEILQRT +IREDV LLSTLFSAC LH+ LDLG +I RLLIEK+PDD STYI+LSN YASVKKWDEV+KVRLK+KELGL+KNPGCSWIE+ K+IHPF V DKSHPQ++M
Sbjct:    8 SLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVLFEKMQQSDAK----------------PDKVTFLAILSA-----------------------------------CSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPDIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYIILSNMYASVKKWDEVRKVRLKIKELGLKKNPGCSWIEVGKRIHPFVVEDKSHPQADM 527          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVE------ALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKG-KEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPN 1374
            LKQGKLIHQK+++LGLQN+  LCK+LIN YFSCH   SAKLVFQ+IENP  I+LWNG+M   TKN +F+E      ALELFE + +     PDS T  +V+ +C  L  +  GK IH  L+++GF  D  V+S+LV MY KC   + A  +F+++  ++V  WN++I+ Y   G ++  +ELF +M   G  P   TL++++ +C+R  +L+ G  IH  +I++++  D FV S+L+D+Y KCG +  A+ VF+ +P  NVV+WN MI+ Y   G  +  +  F  M + G  P   TF+S+L ACS+ A L  GK IH F+I + +E +                    + +FEK                               M+++  +P+ +T  +ILSACS    +++G    ++ + +  F+        L+D+  + G + EA  +  R P+
Sbjct:   19 LKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEPEKALELFEEM-KVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEIN--------------------EVLFEK-------------------------------MQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPD 427          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD---QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIP 765
            +L+ GK IH  ++   ++ D  +  +LI+ YF C    SA+ VFQ++   + +S WN +++G+ K   ++EAL +F   +R   + PD+ T+ SVL AC  L  +  GK IHN +I++    + V                    LF++M + D                                 P+ VT   ++S+C+    ++ G     ++I +   +  ++ +  S L+D+ G+ G L  A E+ ++ P
Sbjct:  227 NLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVS-WNVMISGYVKVGSYLEALVIFTD-MRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEV--------------------LFEKMQQSDA-------------------------------KPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHY--SCLIDLLGRVGRLREAYEILQRTP 426          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFV-SDIVVASSLVCMYAK-CNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKC---GCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGD-SISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            GKL+H+K++  GL+ D  +   LI+ Y  C   ++A+L+F+ + N   +  W+ +++ F  N M  +A+  F  +L   +  P+ Y + +V++AC        G++I+  ++KTG++ +D+ V   L+ M+ K       A ++FD+MPER++  W  +I+ + Q G A+ A++LF  M  SG+ P+  T ++V+S+C  L  L  G ++H  +I+  L LD  V  +LVDMY KC   G +D +++VFEQ+P  NV++W ++I AY  +G+     I+ F +M      P   +FSS+L AC   +    G+ ++++ ++  I +   + +SLI +Y  SG +  A+  F+ + + N VS+N ++ GY K      A  +++++ + G+  +A T  S+LS  + + A+ KG++IH  ++   +++N+ +  AL+ MY++CG ++ A  VFN + +R+ +SWTSMIT +  HG A  AL++F +M ++  KP+ +T +AVLSACSHVG++ EG   FN M   +GI PR+EHY+C++DLLGR+G L EA E +  +  +  D  +  TL  ACR+H N +LG   A +++E+ PDD + YI+LSN +AS  +W +V K+R  MKE  L K  GCSWIE+  ++H F VG+ SHPQ+
Sbjct:   63 GKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFY-PNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKGGYKSNQCICNALISMYSRCGNIEAAFQVFNEMEDRNVISWTSMITGFAKHGFATRALEMFHKMLETGTKPNEITYVAVLSACSHVGMISEGQKHFNSMYKEHGIVPRMEHYACMVDLLGRSGLLVEAMEFI-NSMPLMADALVWRTLLGACRVHGNTELGRHAAEMILEQEPDDPAAYILLSNLHASAGQWKDVVKIRKSMKERNLIKEAGCSWIEVENRVHRFHVGETSHPQA 717          

Query:  268 PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEM-PERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIK-DQLVLDSFVTSALVDMYGK-CGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLY---FVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDY-FGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSE 1680
            PD  TY  +LK+C        GK++H  L+++G   D VV ++L+ +Y+KC   + A  +F+ M  +RD+  W+ ++SC+  +    +A+  F  M   GF PN      VI +C+       G  I+  ++K   L  D  V   L+DM+ K  G L  A +VF+++P +N+V W  MI  ++  G +   I  F  M   G  P   T+SS+L AC+    L  GK +H+ +IR  +  D+ +  SL+D+Y      GSV  ++ VFE+MP+ N +SW  +I+ YV+ G+    A+ ++  M    +RPN  + +S+L AC  L+    G++++   +     +   +  +L+ MYA+ G +++A   F+ L  ++ VS+ +++  Y  + ++ EA  LF E+  +       T  ++LS  + +G + +G     +++   G K      + LI +  R G +  A+++     +
Sbjct:   42 PDLTTYSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNLSDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDARKAFDILFEKNLVSYNAIVDGYAKNLKSEEAFLLFNEIADTGIGISAFTFASLLSGAASIGAMGKGEQIHGRLLKG-GYKSNQCICNALISMYSRCGNIEAAFQVFNEMED 518          

Query:  514 GQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIR-NIIEADIYIYSSLIDLYFV-SGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKC---GAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQA-LEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSC----LIDLLGRAGRLNEA 1653
            G+   A    + M      P+  T + ++ SC R  + + G  +H++L++  L LDS V + L+ +Y KCG  + A+ +FE +  K ++V+W++M++ ++        I  F  M   G  P    F++++ ACS +     G+ I+ F+++   +EAD+ +   LID++   SG + SA  VF+KMP+ N V+W +MI+ + ++G    A+ ++ DM+ +G  P+  T +S+LSAC++L  L  GK++H  VI      +  +  +L+DMYAKC   G+VD++  VF ++P  + +SWT++ITAY   G+   EA++LF +M   + +P+  +  +VL AC ++        +  + + +Y +K  I   +C    LI +  R+GR+ +A
Sbjct:   23 GRLHHAFSTLDLMTQQNAPPDLTTYSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPERNLVTWTLMITRFAQLGCARDAIDLFLDMELSGYVPDRFTYSSVLSACTELGLLALGKQLHSRVIRLGLALDVCVGCSLVDMYAKCAADGSVDDSRKVFEQMPEHNVMSWTAIITAYVQSGECDKEAIELFCKMISGHIRPNHFSFSSVLKACGNL-----SDPYTGEQVYSYAVKLGIASVNCVGNSLISMYARSGRMEDA 408          

Query: 1117 VGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPN-RDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGR-AGRLNEAYEILQRTSE 1680
            VG    A +  D M +    P+  T + +L +C +    + GK +HR ++ S  E + +++  L+ +Y+KCG  + A  +F  + N RD VSW++M++ + ++    +A+  F +M +    P+     AV+ ACS+      G   +  ++    ++  +     LID+  + +G L  AY++  +  E
Sbjct:   22 VGRLHHAFSTLDLMTQQNAPPDLTTYSILLKSCIRFRNFQLGKLVHRKLMQSGLELDSVVLNTLISLYSKCGDTETARLIFEGMGNKRDLVSWSAMVSCFANNSMEWQAIWTFLDMLELGFYPNEYCFAAVIRACSNANYAWVGEIIYGFVVKTGYLEADVCVGCELIDMFVKGSGDLGSAYKVFDKMPE 211          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEA--LELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQ 1971
            N SL++GK +H +++     +   +  +L+N Y  C     AK VF+ I+N   +S WN ++ G++++     +  +ELF+ + R     P+++T+  V  A   L     G++ H   IK     D+ V SSL+ MY K  +   A ++FD MPER+   W T+IS Y     A +A+ LF  MR      N    T+V+S+      +  G +IH   +K+ L+    V +ALV MY KCG LD A + FE    KN + W++MI  Y+ +GDS   ++ F  M+  G  P+  TF  ++ ACS       GK +H ++++   E+ IY+ ++L+D+Y    S+  A+  F+ + + + V W  MI GYV+ G+   AL++Y  M+  G+ PN +T+ S+L ACS LAALE+GK+IH   +   F     +  AL  MYAKCG + +   VF R+P RD +SW +MI+    +G   EAL+LF EMQ    KPD VT + +LSACSH+GLV+ G  +F  M   +G+ PR+EHY+C++D+L RAG+L EA E  + ++ I   + L   +  ACR +RN +LG      L+E    + S Y++LS+ Y+++ +W++V++VR  MK  G+ K PGCSWIE+   +H F V D+ HPQ
Sbjct:   19 NRSLQKGKALHAQIIKSS-SSCVYIANSLVNLYAKCQRLREAKFVFERIQNKDVVS-WNCIINGYSQHGPSGSSHVMELFQRM-RAENTAPNAHTFAGVFTAASTLVDAAGGRLAHAVAIKMDSCRDVFVGSSLMNMYCKAGLTPEARKVFDTMPERNSVSWATMISGYASQKLAAEALGLFRLMRREEEGENEFVFTSVLSALTLPELVNNGKQIHCIAVKNGLLSIVSVGNALVTMYAKCGSLDDALQTFETSSDKNSITWSAMITGYAQSGDSDKALKLFSSMHLSGIRPSEFTFVGVINACSDLGAAWEGKQVHDYLLKLGFESQIYVMTALVDMYAKCSSIVDARKGFDYLQEPDIVLWTSMIGGYVQNGENEDALSLYGRMEMEGILPNELTMASVLKACSSLAALEQGKQIHARTVKYGFGLEVPIGSALSTMYAKCGCLKDGTLVFRRMPARDVISWNAMISGLSQNGCGKEALELFEEMQLEGTKPDYVTFVNILSACSHMGLVERGWGYFRMMFDEFGMDPRVEHYACMVDILSRAGKLKEAIEFTE-SATIDHGMCLWRIILGACRNYRNYELGAYAGEKLMELGSQESSAYVLLSSIYSALGRWEDVERVRRMMKLRGVSKEPGCSWIELKSGVHVFVVKDQMHPQ 672          

Query:    7 NSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFV--TSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            + L QG+  H +ML  G+  +  L   L+  Y  C     AK +F  +    S   WN ++ GFT    F  AL  +  +L    + PD YT+P V+KACG L  V  G+++H+ +   GF  D+ V SSL+  Y++      A  LFD MP +D   WN +++ Y ++G    A  +F +MR +   PNSVT   V+S CA    +  G ++H  ++   L +DS V  T AL+D+Y KC  ++MA+++F+Q    ++V   +MI+ Y + G + + ++ FR + +E       T +S+L AC+  A L  GK +H  +++N      Y+ S+++D+Y   G +  A   F  +   + V WN MI+   + G    A+ ++  M  AG + + +++++ LSAC+ L AL  GKEIH  ++   F ++     AL+DMY+KCG +D A  VF+ +  ++ VSW S+I AYG+HG+  ++L LF  M     +PD VT LA++SAC H G VDEG H+F  M    GI  R+EHY+C++DL GRAGRLNEA+ ++  +     D  +  TL  ACRLH N++L    +R L + +P +   Y++LSN +A+  +W+ V K+R  MKE G++K PGCSWI++N   H F   D+SHPQS
Sbjct:   60 SGLSQGRQAHAQMLVNGIGYNGILGTKLLGMYVLCGAFLDAKNIFYQLRLWCS-EPWNWMIRGFTMMGQFDFALLFYFKMLGCGTL-PDKYTFPYVIKACGGLNSVALGRVVHDKIQFMGFELDVFVGSSLIKFYSENGCIHDARYLFDRMPSKDGVLWNVMLNGYVKNGDWDNATGVFMEMRRTETNPNSVTFACVLSVCASEIMINFGSQLHGLVVSSGLEMDSPVANTFALIDIYFKCRDVEMARKIFDQRTPVDIVVCTAMISGYVLNGMNNNALEIFRWLLQERMRANSVTLASVLPACAGLAALTLGKELHGHILKNGHGGSCYVGSAIMDMYAKCGRLDLAHQTFIGISDKDAVCWNSMITSCSQNGKPEEAIDLFRQMGMAGTKYDCVSISAALSACANLPALHYGKEIHAFMMRGAFRSDLFAESALIDMYSKCGNLDLACRVFDTMEEKNEVSWNSIIAAYGNHGRLKDSLNLFHGMLGDGIQPDHVTFLAIISACGHAGQVDEGIHYFRCMTEELGIMARMEHYACMVDLFGRAGRLNEAFGMI-NSMPFSPDAGVWGTLLGACRLHGNVELAEVASRNLFDLDPQNSGYYVLLSNVHANAGQWESVLKIRSLMKERGVQKVPGCSWIDVNNTTHMFVAADRSHPQS 714          

Query:  586 LTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMG--ALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSAC 1725
            L +++ +C     L +G + H +++ + +  +  + + L+ MY  CG    AK +F Q+ +     WN MI  +++ G     + F+ +M   GT P   TF  ++ AC     +  G+ +H  +     E D+++ SSLI  Y  +G +  A+ +F++MP  + V WNVM++GYVK GD+  A  ++ +M+     PN++T   +LS C+    +  G ++H  V+ S  E +  +    AL+D+Y KC  V+ A  +F++    D V  T+MI+ Y  +G    AL++F  + Q   + + VTL +VL AC+ +  +  G      ++ N G        S ++D+  + GRL+ A++     S+  +D    +++ ++C
Sbjct:   49 LVSILQTCTDPSGLSQGRQAHAQMLVNGIGYNGILGTKLLGMYVLCGAFLDAKNIFYQLRLWCSEPWNWMIRGFTMMGQFDFALLFYFKMLGCGTLPDKYTFPYVIKACGGLNSVALGRVVHDKIQFMGFELDVFVGSSLIKFYSENGCIHDARYLFDRMPSKDGVLWNVMLNGYVKNGDWDNATGVFMEMRRTETNPNSVTFACVLSVCASEIMINFGSQLHGLVVSSGLEMDSPVANTFALIDIYFKCRDVEMARKIFDQRTPVDIVVCTAMISGYVLNGMNNNALEIFRWLLQERMRANSVTLASVLPACAGLAALTLGKELHGHILKN-GHGGSCYVGSAIMDMYAKCGRLDLAHQTFIGISD--KDAVCWNSMITSC 427          

Query:  856 NREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITN-YGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEK 1782
            N +  +P L    SIL  C+  + L  G+  HA M+ N I  +  + + L+ +Y + G+   AKN+F ++    +  WN MI G+  +G +  AL  Y  M   G  P+  T   ++ AC  L ++  G+ +H  +    FE +  +  +L+  Y++ G + +A  +F+R+P++D V W  M+  Y  +G    A  +F EM+++   P+ VT   VLS C+   +++ G      ++++   +   + +   LID+  +   +  A +I  + + +  D+ + + + S   L+   +  ++I R L+++
Sbjct:   41 NDDSLAPQLV---SILQTCTDPSGLSQGRQAHAQMLVNGIGYNGILGTKLLGMYVLCGAFLDAKNIFYQLRLWCSEPWNWMIRGFTMMGQFDFALLFYFKMLGCGTLPDKYTFPYVIKACGGLNSVALGRVVHDKIQFMGFELDVFVGSSLIKFYSENGCIHDARYLFDRMPSKDGVLWNVMLNGYVKNGDWDNATGVFMEMRRTETNPNSVTFACVLSVCASEIMINFGSQLHGLVVSSGLEMDSPVANTFALIDIYFKCRDVEMARKIFDQRTPV--DIVVCTAMISGYVLNGMNNNALEIFRWLLQE 345          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMI-RNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKM--PKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNR-DPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            +L  G L+H + +  GL ++  +  +LIN Y  C   ++AK VF +++  + + LWN ++ G+ +N    + ++LF S +R     PD +TY S+L AC  L  +  G+ +H+ +IK  F  ++ V ++LV MYAKC   + A + F+ +  RD   WN +I  Y Q+    +A  +F +M   G  P+ V+L +++S CA L  LE+G ++H  L+K  L    +  S+L+DMY KCG ++ A+ VF  +P ++VV+ N++IA Y+   D +  I  F+ M  EG +P+  TF+S+L AC+   +L  G+ IH  +  R ++    ++  SL+ +Y  S   + A  +F +   PK+ T+ W  +ISG+ + G    AL +Y +M     RP+  T  S+L ACS LA+L  G+ IH  +     +++E+   A++DMYAKCG +  ++ VF  + ++ D +SW SMI  +  +G A  ALK+F EM+ +  +PD VT L VL+ACSH G V EG   F+ M+ +Y I PR++H +C+IDLLGR G L EA E + + +    +  + +TL  ACR+H +   G + A  LIE  P++ S Y++LSN YA+   WDEV  VR  M+E GLRK PGCSWI + +K + F  GDK HP +
Sbjct:  364 ALNYGLLVHAQAIKQGLNSNVYVGSSLINMYAKCEKMEAAKKVFDALDERNLV-LWNAMLGGYAQNGYASKVMKLF-SEMRGCGFWPDEFTYTSILSACACLECLEMGRQLHSFIIKHNFEYNLFVENTLVDMYAKCGALEEARQQFEFIRNRDNVSWNAIIVGYVQEEDEDEAFNMFRRMILDGIAPDEVSLASILSGCANLQALEQGEQVHCFLVKSGLQTCLYAGSSLIDMYVKCGAIEAARYVFSCMPSRSVVSMNAIIAGYA-QNDLVEAIDLFQEMQNEGLNPSEITFASLLDACTGPYKLNLGRQIHCLIQKRGLLYDGDFLGVSLLVMYMNSQRKTDADILFSEFQYPKS-TILWTAIISGHTQNGCSEEALQLYQEMHRNNARPDQATFASVLRACSILASLGDGRMIHSLIFHVGLDSDELTGSAVVDMYAKCGDMKSSVQVFEEMGSKNDVISWNSMIVGFAKNGYAENALKIFDEMKHTRIRPDDVTFLGVLTACSHAGRVSEGREIFDIMVHSYKIVPRLDHCACMIDLLGRWGFLKEAEEFIDKLN-FEPNAMIWATLLGACRIHGDDIRGRRAAEKLIELEPENSSPYVLLSNIYAASGNWDEVNSVRRAMREKGLRKLPGCSWIVVGQKTNLFVAGDKFHPSA 1017          

Query:   16 KQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEG--CHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEA 1653
            +  K IH + L  G  +   L   +++ Y  C   + A   F  +E    I  WN V++ +++     + +  F SL     + P+ +TY  VL +C  L  +  GK +H  +IK GF  +     SL+ MY+KC     A ++FD + + D   W  +I+ Y Q G  ++A+++FE M+  G  P+ V   TVI++C  L                                   G LD A ++F Q+P  NVVAWN MI+ +   G  I  I FF+ M + G   T +T  S+L A +    L +G  +HA  I+  + +++Y+ SSLI++Y     + +AK VF+ + + N V WN M+ GY + G     + ++ +M+  G  P+  T TSILSAC+ L  LE G+++H  +I   FE N  +   L+DMYAKCGA++EA   F  + NRD VSW ++I  Y       EA  +F  M      PD V+L ++LS C+++  +++G   H F   +   G++  +   S LID+  + G +  A
Sbjct:   98 RTSKTIHAQTLKFGFGSKGRLGSAIVDLYAKCGNVEFAAKAFNQLEK-RDILAWNSVLSMYSRQGSLEQVIWCFGSLQNCG-VSPNQFTYAIVLSSCARLVDIDLGKQVHCGVIKMGFEFNSFCEGSLIDMYSKCGSLVDARKIFDAVVDPDTVSWTAMIAGYVQVGLPEEALKVFEDMQKLGLVPDQVAFVTVITACVGL-----------------------------------GRLDDACDLFVQMPNTNVVAWNVMISGHVKRGCDIEAIDFFKNMWKTGVKSTRSTLGSVLSAIASLEALNYGLLVHAQAIKQGLNSNVYVGSSLINMYAKCEKMEAAKKVFDALDERNLVLWNAMLGGYAQNGYASKVMKLFSEMRGCGFWPDEFTYTSILSACACLECLEMGRQLHSFIIKHNFEYNLFVENTLVDMYAKCGALEEARQQFEFIRNRDNVSWNAIIVGYVQEEDEDEAFNMFRRMILDGIAPDEVSLASILSGCANLQALEQGEQVHCF---LVKSGLQTCLYAGSSLIDMYVKCGAIEAA 605          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACS 1521
            GK +H  ++ +G + +     +LI+ Y  C     A+ +F ++ +P ++S W  ++ G+ +  +  EAL++FE + +   + PD   + +V+ AC  LG++                                   D A  LF +MP  +V  WN +IS + + G   +A++ F+ M  +G      TL +V+S+ A L  L  G+ +H + IK  L  + +V S+L++MY KC  ++ AK+VF+ +  +N+V WN+M+  Y+  G +   ++ F  M   G  P   T++SIL AC+    L  G+ +H+F+I++  E ++++ ++L+D+Y   G++  A+  FE +   + VSWN +I GYV+  D   A  ++  M   G+ P+ +++ SILS C+ L ALE+G+++H  ++ S  +T      +L+DMY KCGA++ A  VF+ +P+R  VS  ++I  Y +    +EA+ LF EMQ     P  +T  ++L AC+
Sbjct:  201 GKQVHCGVIKMGFEFNSFCEGSLIDMYSKCGSLVDARKIFDAVVDPDTVS-WTAMIAGYVQVGLPEEALKVFEDMQKLGLV-PDQVAFVTVITACVGLGRL-----------------------------------DDACDLFVQMPNTNVVAWNVMISGHVKRGCDIEAIDFFKNMWKTGVKSTRSTLGSVLSAIASLEALNYGLLVHAQAIKQGLNSNVYVGSSLINMYAKCEKMEAAKKVFDALDERNLVLWNAMLGGYAQNGYASKVMKLFSEMRGCGFWPDEFTYTSILSACACLECLEMGRQLHSFIIKHNFEYNLFVENTLVDMYAKCGALEEARQQFEFIRNRDNVSWNAIIVGYVQEEDEDEAFNMFRRMILDGIAPDEVSLASILSGCANLQALEQGEQVHCFLVKSGLQTCLYAGSSLIDMYVKCGAIEAARYVFSCMPSRSVVSMNAIIAGY-AQNDLVEAIDLFQEMQNEGLNPSEITFASLLDACT 662          

Query:  940 KFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR--TSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYI--MLSNTYASVKKWDEVKKV 1863
            K IHA  ++    +   + S+++DLY   G+V  A   F ++ K + ++WN ++S Y + G     +  +  ++  GV PN  T   +LS+C++L  ++ GK++H  VI   FE N    G+L+DMY+KCG++ +A  +F+ + + D VSWT+MI  Y   G   EALK+F +MQ+    PD V  + V++AC  +G +D+ C  F QM         +  ++ +I    + G   EA +  +    + ++     L ++ SA      L+ G+ +    I++  +  + Y+   L N YA  +K +  KKV
Sbjct:  101 KTIHAQTLKFGFGSKGRLGSAIVDLYAKCGNVEFAAKAFNQLEKRDILAWNSVLSMYSRQGSLEQVIWCFGSLQNCGVSPNQFTYAIVLSSCARLVDIDLGKQVHCGVIKMGFEFNSFCEGSLIDMYSKCGSLVDARKIFDAVVDPDTVSWTAMIAGYVQVGLPEEALKVFEDMQKLGLVPDQVAFVTVITACVGLGRLDDACDLFVQMPNT-----NVVAWNVMISGHVKRGCDIEAIDFFKNMWKTGVKSTRSTLGSVLSAIASLEALNYGLLVHAQAIKQGLNS-NVYVGSSLINMYAKCEKMEAAKKV 406          

Query: 1228 ALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEI 1662
            A    K IH   +   F +   +  A++D+YAKCG V+ A   FN+L  RD ++W S+++ Y   G   + +  FG +Q     P+  T   VLS+C+ +  +D G      +I   G +        LID+  + G L +A +I
Sbjct:   96 ASRTSKTIHAQTLKFGFGSKGRLGSAIVDLYAKCGNVEFAAKAFNQLEKRDILAWNSVLSMYSRQGSLEQVIWCFGSLQNCGVSPNQFTYAIVLSSCARLVDIDLGKQVHCGVI-KMGFEFNSFCEGSLIDMYSKCGSLVDARKI 239          

Query:    7 NSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            N +   K+IH +++  GLQ+D  L   LIN        D+A++VF  + + + I+ W+ +++ +++     EAL +F  L R     P+ +   SV++AC  LG V  G  +H  ++++GF  D+ V +SL+  Y+K    + A  +FD++ E+    W T+I+ Y + G++  ++ELF +MR +   P+   +++V+S+C+ L  LE G +IH  +++    +D  V + L+D Y KC  +   +++F+Q+ +KN+++W +MI+ Y         ++ F  MNR G  P     +S+L +C     L  G+ +HA+ I+  +E+D ++ + LID+Y  S  +  AK VF+ M + N +S+N MI GY        AL ++ +M+    +PN  T  ++++A S LA+L  G++ H  ++    +    +  AL+DMYAKCG+++EA  +FN    RD V W SMI+ +  HG+A EAL +F EM +   +P+ VT +AVLSACSH G V++G + FN M   +GIKP  EHY+C++ LLGR+G+L EA E +++   I     +  +L SACR+  N++LG   A + I  +P D  +YI+LSN +AS   W +VKKVR +M    + K PG SWIE+N K++ F   D +H ++++
Sbjct:   63 NPIIHYKIIHGQIIVSGLQSDTFLANILINVCSKSDRVDNARVVFDKMPHKNLIT-WSSMVSMYSQQGYSEEALMVFVDLQRKSGEHPNEFVLASVIRACTQLGVVEKGAQLHGFVVRSGFDQDVYVGTSLIDFYSKNGNIEEARLVFDQLSEKTAVTWTTIIAGYTKCGRSAVSLELFAQMRETNVVPDRYVVSSVLSACSMLEFLEGGKQIHAYVLRRGTEMDVSVVNVLIDFYTKCNRVKAGRKLFDQMVVKNIISWTTMISGYMQNSFDWEAMKLFGEMNRLGWKPDGFACTSVLTSCGSREALEQGRQVHAYTIKANLESDEFVKNGLIDMYAKSNLLIDAKKVFDVMAEQNVISYNAMIEGYSSQEKLSEALELFHEMRVRLQKPNEFTFAALITAASNLASLRHGQQFHNQLVKMGLDFCPFVTNALVDMYAKCGSIEEARKMFNSSIWRDVVCWNSMISTHAQHGEAEEALGMFREMMKEGIQPNYVTFVAVLSACSHAGRVEDGLNHFNSM-PGFGIKPGTEHYACVVSLLGRSGKLFEAKEFIEK-MPIEPAAIVWRSLLSACRIAGNVELGKYAAEMAISTDPKDSGSYILLSNIFASKGMWADVKKVRDRMDSSEVVKEPGRSWIEVNNKVNVFIARDTTHREADI 717          

Query:  247 LRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELF-EKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEK 1782
            L+ P + P    + ++L+   +   +   K+IH  +I +G  SD  +A+ L+ + +K +  D A  +FD+MP +++  W++++S Y Q G +++A+ +F +  R SG  PN   L +VI +C +L  +E+G ++H  +++     D +V ++L+D Y K G ++ A+ VF+Q+  K  V W ++IA Y+  G S   ++ F +M      P     SS+L ACS    L  GK IHA+++R   E D+ + + LID Y     V + + +F++M   N +SW  MISGY++    + A+ ++ +M   G +P+    TS+L++C    ALE+G+++H   I +  E++E +   L+DMYAK   + +A  VF+ +  ++ +S+ +MI  Y S  +  EAL+LF EM+    KP+  T  A+++A S++  +  G  F NQ++   G+       + L+D+  + G + EA ++    S I  DV   +++ S    H   +  + + R ++++
Sbjct:   40 LQIPNLRPKRREFANLLQLSISRNPIIHYKIIHGQIIVSGLQSDTFLANILINVCSKSDRVDNARVVFDKMPHKNLITWSSMVSMYSQQGYSEEALMVFVDLQRKSGEHPNEFVLASVIRACTQLGVVEKGAQLHGFVVRSGFDQDVYVGTSLIDFYSKNGNIEEARLVFDQLSEKTAVTWTTIIAGYTKCGRSAVSLELFAQMRETNVVPDRYVVSSVLSACSMLEFLEGGKQIHAYVLRRGTEMDVSVVNVLIDFYTKCNRVKAGRKLFDQMVVKNIISWTTMISGYMQNSFDWEAMKLFGEMNRLGWKPDGFACTSVLTSCGSREALEQGRQVHAYTIKANLESDEFVKNGLIDMYAKSNLLIDAKKVFDVMAEQNVISYNAMIEGYSSQEKLSEALELFHEMRVRLQKPNEFTFAALITAASNLASLRHGQQFHNQLV-KMGLDFCPFVTNALVDMYAKCGSIEEARKMF--NSSIWRDVVCWNSMISTHAQHGEAEEALGMFREMMKE 549          

Query:   10 SLKQGKLIHQKMLTLGLQNDPA---LCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDP--VSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEI 1923
            S+   K IH   +TLGL + P    L  +L   Y        A+ +F  + NPS  S WN ++  +T + +  +AL LF  +L      PD+YTYP V+KACG       G +IH   + +GF SD  V +SL+ MY  C   + A R+FD M ER +  WNT+I+ Y+++G  ++A+ +F+ M   G  P+  T+ +V+  C+ L +LE G ++H  +    L  D  V ++L+DMY KCG +D A+ +F ++  ++VV+W +M+  Y + GD+ S +   + M  E   P   T +S+L AC+    L HG+ +H + IR  +E+++ + ++LID+Y    +V+ +  VF K  K  T  WN +ISG +  G    A+ ++  M    V PN  T+ S+L A + L  L++ + +H  +I S F +   +   L+D+Y+KCG+++ A N+FN +P +D   ++W+++I  YG HG    A+ LF +M QS  KP+ +T  ++L ACSH GLVDEG   F  M+ +  +  R +HY+C+IDLLGRAGRL EAYE++ RT   R +  +   L  +C +H N++LG   A+ L E  P +   Y++L+N Y++V +W + + VRL M  +GLRK P  S IE+
Sbjct:   33 SIPNTKQIHAHTITLGLLSSPYSHHLLSSLAAAYAMFGCAPHARKLFDELRNPSLFS-WNAMIRMYTNSGLSYDALGLFVQMLASGRRWPDNYTYPFVIKACGDYLLPEMGALIHARTVMSGFDSDAFVQNSLMAMYMNCGEMEVARRVFDLMRERTLVSWNTMINGYFKNGCVKEALMVFDWMIGKGIEPDCATVVSVLPVCSYLKELEVGRRVHALVEVKNLGEDISVWNSLLDMYAKCGNMDEAQMIFYEMDKRDVVSWTTMMNGYILNGDARSALLLCQMMQFESVKPNFVTLASVLSACASLYSLKHGRCLHGWAIRQKLESEVIVETALIDMYAKCNNVNLSFRVFSKTSKQRTAPWNAIISGCIHNGLSRKAIELFKQMLMEAVDPNDATLNSLLPAYAFLTDLQQARNMHGYLIRSGFLSRIEVATILIDIYSKCGSLESAHNIFNGIPKKDKDIITWSAIIAGYGMHGHGETAISLFDQMVQSGVKPNEITFTSILHACSHAGLVDEGLGLFKFMLEDNQMSLRTDHYTCVIDLLGRAGRLEEAYELI-RTMAFRPNHAVWGALLGSCVIHENVELGEVAAKWLFELEPGNTGNYVLLANIYSAVGRWRDAEHVRLMMNNIGLRKTPAHSLIEV 673          

Query:  283 YPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIV---VASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFT-PNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIE 1779
            Y S+L+ C +   +   K IH H I  G +S      + SSL   YA       A +LFDE+    +  WN +I  Y   G +  A+ LF +M  SG   P++ T   VI +C      E G  IH   +      D+FV ++L+ MY  CG +++A+ VF+ +  + +V+WN+MI  Y   G     +  F  M  +G  P   T  S+L  CS   +L  G+ +HA +    +  DI +++SL+D+Y   G++  A+ +F +M K + VSW  M++GY+  GD   AL +   M+   V+PN +T+ S+LSAC+ L +L+ G+ +H   I  + E+  I+  AL+DMYAKC  V+ +  VF++   +    W ++I+    +G + +A++LF +M      P+  TL ++L A + +  + +  +    +I + G   RIE  + LID+  + G L  A+ I     +  +D+   S + +   +H + +  + +   +++
Sbjct:   21 YQSLLQRCTSRKSIPNTKQIHAHTITLGLLSSPYSHHLLSSLAAAYAMFGCAPHARKLFDELRNPSLFSWNAMIRMYTNSGLSYDALGLFVQMLASGRRWPDNYTYPFVIKACGDYLLPEMGALIHARTVMSGFDSDAFVQNSLMAMYMNCGEMEVARRVFDLMRERTLVSWNTMINGYFKNGCVKEALMVFDWMIGKGIEPDCATVVSVLPVCSYLKELEVGRRVHALVEVKNLGEDISVWNSLLDMYAKCGNMDEAQMIFYEMDKRDVVSWTTMMNGYILNGDARSALLLCQMMQFESVKPNFVTLASVLSACASLYSLKHGRCLHGWAIRQKLESEVIVETALIDMYAKCNNVNLSFRVFSKTSKQRTAPWNAIISGCIHNGLSRKAIELFKQMLMEAVDPNDATLNSLLPAYAFLTDLQQARNMHGYLIRS-GFLSRIEVATILIDIYSKCGSLESAHNIFNGIPKKDKDIITWSAIIAGYGMHGHGETAISLFDQMVQ 522          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTP-NSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKS 1962
            G+ IH  ++    + DP L   LI  Y SC     A  +F  +EN S+I  WN ++ GF +N M+ ++LEL+ SL +       S ++     AC     + FG+ +H  +IK  F  D  V +SL+ MYAK    + A ++FD++ +++V   N +IS +  +G+A  A+ L+ KM+ +G TP +S T+++++S C+ +   + G  +H E+IK  +  +  + SAL+ MY KCG  + A  VF  +  ++VVAW SMIA +         +  FR M +EG        +S++ A      +  G  IH F I+  +E+D+++  SL+D+Y   G   SA+ VF  MP  N V+WN MIS Y   G    ++ +   + + G   +++++T++L A S +AAL KGK +H   I  +  ++  +  AL+DMY KCG +  A  +F  +P R+ V+W SMI  YGSHG   EA++LF EM++S   PD VT LA++++CSH G+V+EG + F  M   YG++PR+EHY+ ++DLLGRAGRL++AY  + R   I  D  +   L  ACR HRN++LG  +A  L++  P   S Y+ L N Y  V+ WD    +R  MK  GL+K+PGCSWIE+  ++  FF GD S
Sbjct:  566 GRQIHGYIIRNMFEGDPYLETALIGMYSSCSRPMEAWSLFGKLENRSNIVAWNVMIGGFVENGMWEKSLELY-SLAKNENCKLVSASFTGAFTACSHGEVLDFGRQVHCDVIKMNFQDDPYVCTSLLTMYAKSGSVEDAKKVFDQVLDKEVELRNAMISAFIGNGRAYDALGLYNKMK-AGETPVDSFTISSLLSGCSVVGSYDFGRTVHAEVIKRSMQSNVAIQSALLTMYYKCGSTEDADSVFYTMKERDVVAWGSMIAGFCQNRRFKDALDLFRAMEKEGVKADSDVMTSVISAGLGLENVELGHLIHGFAIKRGLESDVFVACSLVDMYSKFGFAESAEMVFSSMPNKNLVAWNSMISCYSWNGLPEMSINLLPQILQHGFYLDSVSITTVLVAVSSVAALLKGKTLHAYQIRLQIPSDLQVENALIDMYVKCGCLKYAQLIFENMPRRNLVTWNSMIAGYGSHGNCEEAVRLFKEMKRSETAPDEVTFLALITSCSHSGMVEEGLNLFQLMRIEYGVEPRMEHYASVVDLLGRAGRLDDAYSFI-RGMPIDADRSVWLCLLFACRAHRNMELGELVADNLLKMEPARGSNYVPLLNLYGEVEMWDRAANLRASMKGRGLKKSPGCSWIEVKNRVDVFFSGDSS 1210          

Query:    7 NSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVF----QSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLL--IEKNPDD 1794
            ++L  G+ IH  ++T+GLQ+DP +  +LIN Y  C    SA  VF    +S ++   I++WN V+ G+ K   F E L  F   ++   I PD Y+   VL  C  L     G+ IH ++I+  F  D  + ++L+ MY+ C+    A  LF ++  R ++  WN +I  + ++G  +K++EL+   +N      S + T   ++C+    L+ G ++H ++IK     D +V ++L+ MY K G ++ AK+VF+Q+  K V   N+MI+A+   G +   +  + +M    T     T SS+L  CS       G+ +HA +I+  +++++ I S+L+ +Y+  GS   A +VF  M + + V+W  MI+G+ +   +  AL ++  M++ GV+ ++  +TS++SA   L  +E G  IH   I    E++  +  +L+DMY+K G  + A  VF+ +PN++ V+W SMI+ Y  +G    ++ L  ++ Q     D V++  VL A S V  + +G       I    I   ++  + LID+  + G L  A  I +     R ++   +++ +    H N +  V++ + +   E  PD+
Sbjct:  455 SNLYHGRTIHASIVTMGLQSDPYIATSLINMYVKCGLLGSALQVFDKMSESRDSAPDITVWNPVIDGYFKYGHFEEGLAQF-CRMQELGIRPDGYSLSIVLGICNRLSWYMAGRQIHGYIIRNMFEGDPYLETALIGMYSSCSRPMEAWSLFGKLENRSNIVAWNVMIGGFVENGMWEKSLELYSLAKNENCKLVSASFTGAFTACSHGEVLDFGRQVHCDVIKMNFQDDPYVCTSLLTMYAKSGSVEDAKKVFDQVLDKEVELRNAMISAFIGNGRAYDALGLYNKMKAGETPVDSFTISSLLSGCSVVGSYDFGRTVHAEVIKRSMQSNVAIQSALLTMYYKCGSTEDADSVFYTMKERDVVAWGSMIAGFCQNRRFKDALDLFRAMEKEGVKADSDVMTSVISAGLGLENVELGHLIHGFAIKRGLESDVFVACSLVDMYSKFGFAESAEMVFSSMPNKNLVAWNSMISCYSWNGLPEMSINLLPQILQHGFYLDSVSITTVLVAVSSVAALLKGKTLHAYQI-RLQIPSDLQVENALIDMYVKCGCLKYAQLIFENMP--RRNLVTWNSMIAGYGSHGNCEEAVRLFKEMKRSETAPDE 1053          

Query:  214 FVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-----DVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAG 1638
            + +ALEL  S   +  +    +T+PS+LK C +L  +  G+ IH  ++  G  SD  +A+SL+ MY KC +   A+++FD+M E      D+  WN VI  Y++ G  ++ +  F +M+  G  P+  +L+ V+  C RL     G +IH  +I++    D ++ +AL+ MY  C     A  +F ++  + N+VAWN MI  +   G     ++ +     E       +F+    ACS    L  G+ +H  +I+   + D Y+ +SL+ +Y  SGSV  AK VF+++        N MIS ++  G  + AL +Y+ MK      ++ T++S+LS CS + + + G+ +H  VI    ++N  +  ALL MY KCG+ ++A +VF  +  RD V+W SMI  +  + +  +AL LF  M++   K D   + +V+SA   +  V+ G H  +      G++  +     L+D+  + G
Sbjct:  422 YSQALEL-HSKTPHSALTTAKFTFPSLLKTCASLSNLYHGRTIHASIVTMGLQSDPYIATSLINMYVKCGLLGSALQVFDKMSESRDSAPDITVWNPVIDGYFKYGHFEEGLAQFCRMQELGIRPDGYSLSIVLGICNRLSWYMAGRQIHGYIIRNMFEGDPYLETALIGMYSSCSRPMEAWSLFGKLENRSNIVAWNVMIGGFVENGMWEKSLELYSLAKNENCKLVSASFTGAFTACSHGEVLDFGRQVHCDVIKMNFQDDPYVCTSLLTMYAKSGSVEDAKKVFDQVLDKEVELRNAMISAFIGNGRAYDALGLYNKMKAGETPVDSFTISSLLSGCSVVGSYDFGRTVHAEVIKRSMQSNVAIQSALLTMYYKCGSTEDADSVFYTMKERDVVAWGSMIAGFCQNRRFKDALDLFRAMEKEGVKADSDVMTSVISAGLGLENVELG-HLIHGFAIKRGLESDVFVACSLVDMYSKFG 900          

Query:  493 ISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQI-----PIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMP-KTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLD 1746
            I    Q G+  +A+EL  K  +S  T    T  +++ +CA L +L  G  IH  ++   L  D ++ ++L++MY KCG L  A +VF+++        ++  WN +I  Y   G     +  F RM   G  P   + S +L  C+R +  + G+ IH ++IRN+ E D Y+ ++LI +Y        A ++F K+  ++N V+WNVMI G+V+ G +  +L +Y   K    +  + + T   +ACS    L+ G+++H  VI   F+ +  +  +LL MYAK G+V++A  VF+++ +++     +MI+A+  +G+A +AL L+ +M+      D  T+ ++LS CS VG  D G     ++I    ++  +   S L+ +  + G   +A  +     E R+ V   S +   C+  R  D
Sbjct:  413 IKALVQQGKYSQALELHSKTPHSALTTAKFTFPSLLKTCASLSNLYHGRTIHASIVTMGLQSDPYIATSLINMYVKCGLLGSALQVFDKMSESRDSAPDITVWNPVIDGYFKYGHFEEGLAQFCRMQELGIRPDGYSLSIVLGICNRLSWYMAGRQIHGYIIRNMFEGDPYLETALIGMYSSCSRPMEAWSLFGKLENRSNIVAWNVMIGGFVENGMWEKSLELYSLAKNENCKLVSASFTGAFTACSHGEVLDFGRQVHCDVIKMNFQDDPYVCTSLLTMYAKSGSVEDAKKVFDQVLDKEVELRNAMISAFIGNGRAYDALGLYNKMKAGETPVDSFTISSLLSGCSVVGSYDFGRTVHAEVIKR-SMQSNVAIQSALLTMYYKCGSTEDADSVFYTMKE-RDVVAWGSMIAGFCQNRRFKD 834          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDS---AKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNS--GFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKT--NTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            +NS ++GK IH +M++ G   D  L   ++  Y      D    A+ +F+ +    +++ WN ++  + +   ++EA  +F+ +L+   + PD++T+ S L+ CGAL     GK +H+ LI  GF  D  V ++L+ MYAKC+  +  +++FDEM ER+   WN++IS   Q G    A+ LF +M+ S  G  P+  T TT+++ CA   +  +G +IH  LI+  +  +  V + LV MY +CG L+ AKE+F ++  +N  +WNSMI  Y   G++   ++ F++M   G  P   + SS+L +C   +    G+ +H F++RN +E +  +   L+D+Y   GS+  A  V+++  K   NT  WN +++GY   G    +   + +M E+ +  + +T+ +I++    L  LE                      AL+DMY+KCGA+ +A  VF+ +  ++ VSW +MI+ Y  HG + EAL L+ EM +    P+ VT LA+LSACSH GLV+EG   F  M  +Y I+ + EHY+C++DLLGRAGRL +A E +++   I  +V     L  ACR+H+++D+G   A+ L E +P +   Y+++SN YA+  +W EV+ +R  MK  G++K+PG SWIEIN +I  F  G K+HP++E
Sbjct:   84 SNSFQRGKSIHTQMISNGYNPDAYLMTKILMLYARSGCLDDLCYARKLFEEMPE-RNLTAWNTMILAYARVDDYMEAWGIFDRMLKIG-VCPDNFTFASALRVCGALRSRDGGKQVHSKLIACGFKGDTFVGNALIDMYAKCDDEESCLKVFDEMGERNQVTWNSIISAEAQFGHFNDALVLFLRMQESEDGIQPDQFTFTTLLTLCANQRNDNQGRQIHAHLIRANITKNIIVETELVHMYSECGRLNYAKEIFNRMAERNAYSWNSMIEGYQQNGETQEALRLFKQMQLNGIKPDCFSLSSMLSSCVSLSDSQKGRELHNFIVRNTMEEEGILQVVLVDMYAKCGSMDYAWKVYDQTIKKDRNTALWNSILAGYANKGLKKESFNHFLEMLESDIEYDVLTMVTIVN----LLVLET---------------------ALVDMYSKCGAITKARTVFDNMNGKNIVSWNAMISGYSKHGCSKEALILYEEMPKKGMYPNEVTFLAILSACSHTGLVEEGLRIFTSMQEDYNIEAKAEHYTCMVDLLGRAGRLEDAKEFVEK-MPIEPEVSTWGALLGACRVHKDMDMGRLAAQRLFELDPQNPGPYVIMSNIYAAAGRWKEVEDIRQMMKMKGVKKDPGVSWIEINSEIQIFHAGSKTHPKTE 720          

Query:  574 NSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLD---MAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEA--GVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRT 1674
            N +  +++I  C      +RG  IH ++I +    D+++ + ++ +Y + GCLD    A+++FE++P +N+ AWN+MI AY+   D +     F RM + G  P   TF+S L  C        GK +H+ +I    + D ++ ++LID+Y       S   VF++M + N V+WN +IS   + G +  AL ++  M+E+  G++P+  T T++L+ C+      +G++IH  +I +    N I+   L+ MY++CG ++ A  +FNR+  R+  SW SMI  Y  +G+  EAL+LF +MQ +  KPD  +L ++LS+C  +    +G    N ++ N   +  I     L+D+  + G ++ A+++  +T
Sbjct:   70 NPLPYSSLIQDCIDSNSFQRGKSIHTQMISNGYNPDAYLMTKILMLYARSGCLDDLCYARKLFEEMPERNLTAWNTMILAYARVDDYMEAWGIFDRMLKIGVCPDNFTFASALRVCGALRSRDGGKQVHSKLIACGFKGDTFVGNALIDMYAKCDDEESCLKVFDEMGERNQVTWNSIISAEAQFGHFNDALVLFLRMQESEDGIQPDQFTFTTLLTLCANQRNDNQGRQIHAHLIRANITKNIIVETELVHMYSECGRLNYAKEIFNRMAERNAYSWNSMIEGYQQNGETQEALRLFKQMQLNGIKPDCFSLSSMLSSCVSLSDSQKGRELHNFIVRNTMEEEGILQV-VLVDMYAKCGSMDYAWKVYDQT 440          

Query: 1180 NAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDE---ALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRA-------------------------------GRLNEAYEILQRTSE----IREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKN 1785
            N +  +S++  C    + ++GK IH  +I + +  +  +M  +L +YA+ G +D+   A  +F  +P R+  +W +MI AY      +EA  +F  M +    PD  T  + L  C  +   D G    +++I   G K      + LID+  +                                G  N+A  +  R  E    I+ D    +TL + C   RN + G +I   LI  N
Sbjct:   70 NPLPYSSLIQDCIDSNSFQRGKSIHTQMISNGYNPDAYLMTKILMLYARSGCLDDLCYARKLFEEMPERNLTAWNTMILAYARVDDYMEAWGIFDRMLKIGVCPDNFTFASALRVCGALRSRDGGKQVHSKLIA-CGFKGDTFVGNALIDMYAKCDDEESCLKVFDEMGERNQVTWNSIISAEAQFGHFNDALVLFLRMQESEDGIQPDQFTFTTLLTLCANQRNDNQGRQIHAHLIRAN 308          

Query:   25 KLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQ 1971
            K I  +++  G+  D  L  +L+N Y  C     A+ V + +     +  WN  ++     +   EA++LF  L+R+  I  + + + S++ A  +LG   +G+ IH  + K GF SDI+++++ V MY K    +   + F  M   ++A  N ++S +       +   +  ++   GF PN  T  +++ +CA   DL  G  IH ++IK  +  DS + ++LV++Y KCG  + A +VF +IP ++VV+W ++I  +   G   S ++ F +M  EG +P + TF SIL +CS  + +  GK +HA +++N ++ + ++ ++L+D+Y  +  +  A+ +F ++ K +  +W V+++GY + G    A+  +  M+  GV+PN  T+ S LS CS++A L+ G+++H   I +    +  +  AL+DMYAKCG V++A  VF+ L +RD VSW ++I  Y  HGQ  +ALK F  M      PD VT + VLSACSH+GL++EG   FN +   YGI P IEHY+C++D+LGRAG+ +E    ++   ++  +V +  T+  AC++H N++ G + A  L E  P+  S YI+LSN +A+   WD+V  VR  M   G++K PGCSW+E+N ++H F   D SHP+
Sbjct:    9 KKIIFRVIKNGICPDSHLWSSLVNVYVKCESLQCARQVLEEMPI-QDVQQWNQKLSSANSPYPLQEAVQLFY-LMRHTRIRLNQFIFASLISAAASLGDNHYGESIHACVCKYGFESDILISNAFVTMYMKTQSVENGWQFFKAMMIENLASRNNLLSGFCDTETCDQGPRILIQLLVEGFEPNMYTFISILKTCASKGDLNEGKAIHGQVIKSGINPDSHLWNSLVNVYAKCGSANYACKVFGEIPERDVVSWTALITGFVAEGYG-SGLRIFNQMLAEGFNPNMYTFISILRSCSSLSDVDLGKQVHAQIVKNSLDGNDFVGTALVDMYAKNRFLEDAETIFNRLIKRDLFAWTVIVAGYAQDGQGEKAVKCFIQMQREGVKPNEFTLASSLSGCSRIATLDSGRQLHSMAIKAGQSGDMFVASALVDMYAKCGCVEDAEVVFDGLVSRDTVSWNTIICGYSQHGQGGKALKAFEAMLDEGTVPDEVTFIGVLSACSHMGLIEEGKKHFNSLSKIYGITPTIEHYACMVDILGRAGKFHEVESFIEE-MKLTSNVLIWETVLGACKMHGNIEFGERAAMKLFELEPEIDSNYILLSNMFAAKGMWDDVTNVRALMSTRGVKKEPGCSWVEVNGQVHVFLSHDGSHPK 653          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNI--IEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKT-NTVSWNVMI 1101
            L +GK IH +++  G+  D  L  +L+N Y  C   + A  VF  I     +S W  ++TGF     +   L +F  +L   +  P+ YT+ S+L++C +L  V  GK +H  ++K     +  V ++LV MYAK    + A  +F+ + +RD+  W  +++ Y QDGQ +KA++ F +M+  G  PN  TL + +S C+R+  L+ G ++H   IK     D FV SALVDMY KCGC++ A+ VF+ +  ++ V+WN++I  YS  G     ++ F  M  EGT P   TF  +L ACS    +  GK  H   +  I  I   I  Y+ ++D+   +G     ++  E+M  T N + W  ++
Sbjct:  207 LNEGKAIHGQVIKSGINPDSHLWNSLVNVYAKCGSANYACKVFGEIPERDVVS-WTALITGFVAEG-YGSGLRIFNQMLAEGF-NPNMYTFISILRSCSSLSDVDLGKQVHAQIVKNSLDGNDFVGTALVDMYAKNRFLEDAETIFNRLIKRDLFAWTVIVAGYAQDGQGEKAVKCFIQMQREGVKPNEFTLASSLSGCSRIATLDSGRQLHSMAIKAGQSGDMFVASALVDMYAKCGCVEDAEVVFDGLVSRDTVSWNTIICGYSQHGQGGKALKAFEAMLDEGTVPDEVTFIGVLSACSHMGLIEEGK-KHFNSLSKIYGITPTIEHYACMVDILGRAGKFHEVESFIEEMKLTSNVLIWETVL 568          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            LKQGKLIHQK+++LGLQN+  LCK+LIN YFSCH   SAKLVFQ+IENP  I+LWNG+M   TKN +F+E LE+F  LL +PY+ PD++TYPSVLKAC  LG+VG+GKM+H H+IK+GF  D+VV SS V MYAKCNVF+ AI+LFDEMPERDVA WN VISCYYQDGQ +KA+ELFE+M+ SGF P+SVTLTTVISSCARL DLERG +IH EL++    LD FV+SALVDMYGKCGCL+MAKEVFEQI  KNVV+WNSMIA YS+ GDS SCI+ FRRM+ EG  PTLTT SSIL+ACSRS  L  GKFIH ++IRN +EADI++ SSLIDLYF  G++ SA+NVF+ MPKTN VSWNVMISGYVKVG Y  AL I+ DM++AGV+P+AIT TS+L ACSQLA LEKGKEIH  +I+S+ E NE++MGALLDMYAKCGAVDEAL++FN+LP RD VSWTSMI AYGSHGQA EALKLF +MQQS+AKPD VT LA+LSACSH GLVDEGC++FNQMI  YG KP +EHYSCLIDLLGR GRL EAYEILQRT +IREDV LLSTLFSAC LH+ LDLG +I RLLIEK+PDD STYI+LSN YASVKKWDEV+KVRLK+KELGL+KNPGCSWIE+ K+IHPF V DKSHPQ++M
Sbjct:   19 LKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPDIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYIILSNMYASVKKWDEVRKVRLKIKELGLKKNPGCSWIEVGKRIHPFVVEDKSHPQADM 674          

Query:  289 SVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPE-RDVACWNTVISCYYQDGQAQKAMELFEKMRNSGF-TPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIE----HYSCLIDLLGRAGRLNEAYEILQRTSE 1680
            S+LK C     +  GK+IH  ++  G  ++I +  SL+ +Y  C++F  A  +F  +    D+  WN +++   ++    + +E+F ++ +  +  P++ T  +V+ +C+ L  +  G  +H  +IK    +D  V S+ V MY KC   + A ++F+++P ++V +WN++I+ Y   G     ++ F  M   G  P   T ++++ +C+R   L  GK IH  ++R+    D ++ S+L+D+Y   G +  AK VFE++ + N VSWN MI+GY   GD    + ++  M E G+RP   T++SIL ACS+   L+ GK IH  +I +  E +  +  +L+D+Y KCG +  A NVF  +P  + VSW  MI+ Y   G  LEAL +F +M+++  KPD +T  +VL ACS + ++++G     + I N+ I+ ++E        L+D+  + G ++EA  I  +  E
Sbjct:    8 SLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKG-----KEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPE 472          

Query:  574 NSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQI--PIKNVVAWNSMIAAYSVTGDSISCIQFFRR-MNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEH----YSCLIDLLGRAGRLNEAYEILQ 1668
            ++  L +++ +C     L++G  IH++++   L  +  +  +L+++Y  C     AK VF+ I  P+ ++  WN ++AA +     I  ++ F R ++     P   T+ S+L ACS   ++ +GK +H  +I++    D+ + SS + +Y        A  +F++MP+ +  SWN +IS Y + G    AL ++++MK +G +P+++T+T+++S+C++L  LE+GKEIH  ++ S F  +  +  AL+DMY KCG ++ A  VF ++  ++ VSW SMI  Y   G +   ++LF  M +   +P   TL ++L ACS    +  G     + I  Y I+ R+E      S LIDL  + G +  A  + Q
Sbjct:    2 DTTKLLSLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPL-DITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLG-----KFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQ 367          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD---QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIP 765
            +L+ GK IH  ++   ++ D  +  +LI+ YF C    SA+ VFQ++   + +S WN +++G+ K   ++EAL +F   +R   + PD+ T+ SVL AC  L  +  GK IHN +I++    + VV  +L+ MYAKC   D A+ +F+++PERD   W ++I+ Y   GQA +A++LFEKM+ S   P+ VT   ++S+C+    ++ G     ++I +   +  ++ +  S L+D+ G+ G L  A E+ ++ P
Sbjct:  323 NLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVS-WNVMISGYVKVGSYLEALVIFTD-MRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHY--SCLIDLLGRVGRLREAYEILQRTP 573          

Query:  883 TTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVS-WNVMISGYVKVGDYFGALAIYDDMKE-AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMI-TNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            T   S+L  C  S  L  GK IH  ++   ++ +I +  SLI+LYF      SAK VF+ +     ++ WN +++   K   +   L ++  +     ++P+A T  S+L ACS L  +  GK +H  VI S F  + ++M + + MYAKC   ++A+ +F+ +P RD  SW ++I+ Y   GQ  +AL+LF EM+ S  KPD VTL  V+S+C+ +  ++ G     +++ + + +   +   S L+D+ G+ G L  A E+ ++
Sbjct:    4 TKLLSLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVS--SALVDMYGKCGCLEMAKEVFEQ 267          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            GKLIHQK+++LGLQN+  LCK+LIN YFSCH   SAKLVFQ+IENP  I+LWNG+M   TKN +F+E LE+F  LL +PY+ PD++TYPSVLKAC  LG+VG+GKM+H H+IK+GF  D+VV SS V MYAKCNVF+ AI+LFDEMPERDVA WN VISCYYQDGQ +KA+ELFE+M+ SGF P+SVTLTTVISSCARL DLERG +IH EL++    LD FV+SALVDMYGKCGCL+MAKEVFEQI  KNVV+WNSMIA YS+ GDS SCI+ FRRM+ EG  PTLTT SSIL+ACSRS  L  GKFIH ++IRN +EADI++ SSLIDLYF  G++ SA+NVF+ MPKTN VSWNVMISGYVKVG Y  AL I+ DM++AGV+P+AIT TS+L ACSQLA LEKGKEIH  +I+S+ E NE++MGALLDMYAKCGAVDEAL++FN+LP RD VSWTSMI AYGSHGQA EALKLF +MQQS+AKPD VT LA+LSACSH GLVDEGC++FNQMI  YG KP +EHYSCLIDLLGR GRL EAYEILQRT +IREDV LLSTLFSAC LH+ LDLG +I RLLIEK+PDD STYI+LSN YASVKKWDEV+KVRLK+KELGL+KNPGCSWIE+ K+IHPF V DKSHPQ++M
Sbjct:  214 GKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPDIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYIILSNMYASVKKWDEVRKVRLKIKELGLKKNPGCSWIEVGKRIHPFVVEDKSHPQADM 866          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNI-IEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNV 1356
            L++GK IH +++  G   D  +   L++ Y  C   + AK VF+ I+  + +S WN ++ G++        +ELF   +    I P   T  S+L AC     +  GK IH ++I+    +DI V SSL+ +Y KC     A  +F  MP+ +V  WN +IS Y + G   +A+ +F  MR +G  P+++T T+V+ +C++L  LE+G +IH  +I+ +L ++  V  AL+DMY KCG +D A  +F Q+P ++ V+W SMIAAY   G +   ++ F +M +    P   TF +IL ACS +  +  G +    MI     +  +  YS LIDL    G +  A  + ++ P                                  +R +   ++++ SAC     L+ G++I R +I+ + +     +  L +MYA     DE   V
Sbjct:  415 LERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVS-WNSMIAGYSLKGDSKSCIELFRR-MDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTP---------------------------------DIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYI-ILSNMYASVKKWDEVRKV 827          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD---QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIP 765
            +L+ GK IH  ++   ++ D  +  +LI+ YF C    SA+ VFQ++   + +S WN +++G+ K   ++EAL +F   +R   + PD+ T+ SVL AC  L  +  GK IHN +I++    + VV  +L+ MYAKC   D A+ +F+++PERD   W ++I+ Y   GQA +A++LFEKM+ S   P+ VT   ++S+C+    ++ G     ++I +   +  ++ +  S L+D+ G+ G L  A E+ ++ P
Sbjct:  515 NLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVS-WNVMISGYVKVGSYLEALVIFTD-MRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHY--SCLIDLLGRVGRLREAYEILQRTP 765          

Query:  931 LHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVS-WNVMISGYVKVGDYFGALAIYDDMKE-AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMI-TNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            L GK IH  ++   ++ +I +  SLI+LYF      SAK VF+ +     ++ WN +++   K   +   L ++  +     ++P+A T  S+L ACS L  +  GK +H  VI S F  + ++M + + MYAKC   ++A+ +F+ +P RD  SW ++I+ Y   GQ  +AL+LF EM+ S  KPD VTL  V+S+C+ +  ++ G     +++ + + +   +   S L+D+ G+ G L  A E+ ++
Sbjct:  212 LLGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVS--SALVDMYGKCGCLEMAKEVFEQ 459          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            + SLKQGKLIHQK++TLGLQND  LCKNLIN Y SCH  D AK VF ++ENP  ISLWNG+M G+TKN+M+VEALELFE LL YPY+ PDSYTYPSVLKACG L +   GKMIH  L+KTG + DIVV SSLV MYAKCN F+ AI LF+EMPE+DVACWNTVISCYYQ G  ++A+E F  MR  GF PNSVT+TT ISSCARL DL RGM+IH+ELI    +LDSF++SALVDMYGKCG L+MA EVFEQ+P K VVAWNSMI+ Y + GDSISCIQ F+RM  EG  PTLTT SS+++ CSRSA+LL GKF+H + IRN I++D++I SSL+DLYF  G V  A+N+F+ +PK+  VSWNVMISGYV  G  F AL ++ +M+++ V P+AIT TS+L+ACSQLAALEKG+EIH  +I+ + + NE++MGALLDMYAKCGAVDEA +VF  LP RD VSWTSMITAYGSHGQA  AL+LF EM QSN KPD VT LA+LSAC H GLVDEGC++FNQM+  YGI PR+EHYSCLIDLLGRAGRL+EAYEILQ+  EIR+DV+LLSTLFSACRLHRN+DLG +IAR LI+K+PDD STYI+LSN YAS  KWDEV+ VR KMKELGL+KNPGCSWIEIN+KI PFFV D SH   E+
Sbjct:    3 SKSLKQGKLIHQKVVTLGLQNDIFLCKNLINLYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVLKACGGLYKYVLGKMIHTCLVKTGLMMDIVVGSSLVGMYAKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKEALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEVFEQMPKKTVVAWNSMISGYGLKGDSISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEGKFVHGYTIRNRIQSDVFINSSLMDLYFKCGKVELAENIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVEPDAITFTSVLTACSQLAALEKGEEIHNLIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSVFKCLPKRDLVSWTSMITAYGSHGQAYVALELFAEMLQSNMKPDRVTFLAILSACGHAGLVDEGCYYFNQMVNVYGIIPRVEHYSCLIDLLGRAGRLHEAYEILQQNPEIRDDVELLSTLFSACRLHRNIDLGAEIARTLIDKDPDDSSTYILLSNMYASAHKWDEVRVVRSKMKELGLKKNPGCSWIEINQKILPFFVEDNSHLHLEL 661          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            + SLKQGKLIHQK++TLGLQND  LCK LIN Y SCH  D AK VF ++ENP  ISLWNG+M G+TKN+M+VEALELFE LL YPY+ PDSYTYPSV KACG L +   GKMIH  LIKTG + DIVV SSLV MY KCN F+ AI LF+EMPE+DVACWNTVISCYYQ G  + A+E F  MR  GF PNSVT+TT ISSCARL DL RGM+IH+ELI    +LDSF++SALVDMYGKCG L+MA E+FEQ+P K VVAWNSMI+ Y + GD ISCIQ F+RM  EG  PTLTT SS+++ CSRSA+LL GKF+H + IRN I+ D+++ SSL+DLYF  G V  A+ +F+ +PK+  VSWNVMISGYV  G  F AL ++ +M+++ V  +AIT TS+L+ACSQLAALEKGKEIH  +I+ + + NE++MGALLDMYAKCGAVDEA +VF  LP RD VSWTSMITAYGSHG A  AL+LF EM QSN KPD V  LA+LSAC H GLVDEGC++FNQMI  YGI PR+EHYSCLIDLLGRAGRL+EAYEILQ+  EIR+DV+LLSTLFSACRLHRN+DLG +IAR LI+K+PDD STYI+LSN YAS  KWDEV+ VR KMKELGL+KNPGCSWIEIN+KI PFFV D SH   E+
Sbjct:    3 SKSLKQGKLIHQKVVTLGLQNDIFLCKTLINQYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVFKACGGLHRYVLGKMIHTCLIKTGLMMDIVVGSSLVGMYGKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKDALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEIFEQMPKKTVVAWNSMISGYGLKGDIISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEGKFVHGYTIRNRIQPDVFVNSSLMDLYFKCGKVELAEKIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVESDAITFTSVLTACSQLAALEKGKEIHNLIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSVFKCLPKRDLVSWTSMITAYGSHGHAYGALELFAEMLQSNVKPDRVAFLAILSACGHAGLVDEGCYYFNQMINVYGIIPRVEHYSCLIDLLGRAGRLHEAYEILQQNPEIRDDVELLSTLFSACRLHRNIDLGAEIARTLIDKDPDDSSTYILLSNMYASAHKWDEVRVVRSKMKELGLKKNPGCSWIEINQKILPFFVEDNSHLHLEL 661          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSH 1965
            + SLKQGK++HQK++TLGLQND  +CKNLI+ Y SC+  D AK VF  IENP  ISL NG+M G+T+N M+ EAL LF+ L+ YP + PDSYTYPSVLKACG L +V  G+MIH  L+K G + DIVV SSLV MYAKCN F+CA++LFDEMP++DVACWNTVISCYYQ G+ ++A+  F  MR  GF P+SVT+TT ISSCARL DL+RG +IHKEL+     +DSFV++ALVDMYGKCG L+MA EVFEQ+P K VVAWNSMI  Y   GD ISCIQ F+RM  EG  PTLTT +S L+ACS+SAQLL GKF+H ++IRN I+ DI++ SSL+DLYF  G V SA+ +F+ MPKT TVSWNVMISGYV  G  F AL ++ +M ++ V P+AIT TS+L+ACSQLAALEKG+EIH  +++     NE++MGALLDMYAKCGAV+EA  VF  LP RD VSWTSMITAYGSHG+  EAL+LF EM QSN KPD VT LA+LSACSH GLVD+G + FNQMI  YGI PRIEHYSCLI LLGRAGRL+EAYEILQ   EI +D  LLSTLFSACRLH+NLDLGV+IA  LI+K+PDD STYI+LSN YAS  KWDEV+ VR KMK+LGL+KNPGCSWIEIN+KI PFFV D SH
Sbjct:   16 SKSLKQGKVLHQKVVTLGLQNDVYVCKNLISLYVSCNLFDYAKNVFDVIENPFEISLCNGLMAGYTRNCMYDEALGLFDKLMCYPCLKPDSYTYPSVLKACGGLRRVVLGQMIHTCLVKEGLMVDIVVGSSLVGMYAKCNEFECAVKLFDEMPDKDVACWNTVISCYYQSGKFEEALRYFGMMRRFGFEPDSVTITTAISSCARLLDLDRGREIHKELVNSGFRMDSFVSAALVDMYGKCGQLEMAIEVFEQMPNKTVVAWNSMINGYGFKGDGISCIQLFKRMYSEGVKPTLTTLTSTLMACSQSAQLLEGKFVHGYIIRNRIQPDIFLNSSLMDLYFKCGKVESAETIFKLMPKTTTVSWNVMISGYVTEGKLFDALRLFGEMSKSFVEPDAITFTSVLAACSQLAALEKGREIHNLIVERNLGNNEVVMGALLDMYAKCGAVEEAFGVFKCLPERDLVSWTSMITAYGSHGRVYEALELFAEMLQSNVKPDRVTFLAILSACSHAGLVDDGLYHFNQMINVYGIIPRIEHYSCLITLLGRAGRLHEAYEILQSNPEISDDFQLLSTLFSACRLHKNLDLGVEIAENLIDKDPDDSSTYIILSNMYASFGKWDEVRMVRSKMKDLGLKKNPGCSWIEINEKIVPFFVEDNSH 669          

Query:  898 ILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVS-WNVMISGYVKVGDYFGALAIYDD-MKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            +L A   S  L  GK +H  ++   ++ D+Y+  +LI LY        AKNVF+ +     +S  N +++GY +   Y  AL ++D  M    ++P++ T  S+L AC  L  +  G+ IH  ++      + ++  +L+ MYAKC   + A+ +F+ +P++D   W ++I+ Y   G+  EAL+ FG M++   +PD VT+   +S+C+ +  +D G     +++ N G +      + L+D+ G+ G+L  A E+ ++
Sbjct:    9 LLRASVNSKSLKQGKVLHQKVVTLGLQNDVYVCKNLISLYVSCNLFDYAKNVFDVIENPFEISLCNGLMAGYTRNCMYDEALGLFDKLMCYPCLKPDSYTYPSVLKACGGLRRVVLGQMIHTCLVKEGLMVDIVVGSSLVGMYAKCNEFECAVKLFDEMPDKDVACWNTVISCYYQSGKFEEALRYFGMMRRFGFEPDSVTITTAISSCARLLDLDRGREIHKELV-NSGFRMDSFVSAALVDMYGKCGQLEMAIEVFEQ 267          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL+Q KL+HQ++LT+GL++D  LCK+LIN YF+C    SA+LVF++I+  S + +WN +++G++KN MF + L++F+ LL  P   PDS+TYP+V+KA GALG+   G+MIH  ++K+G V D+VVASSLV MYAK N+F+ ++++FDEMPERDVA WNTVIS +YQ G A+KA+ELF +M  S F PNSV++T  IS+C+RL  LERG +IH++ +K +  LD +V SALVDMYG+C  L+MA+EVF+Q+  K++VAWNSMI  Y   GDS SC++   RM  EGT P+ TT +SIL+ACSRS  LLHGKF+H ++IR++++ADIYI  SLIDLYF  G V  A+ VF K  K    SWNVMISGYV VG++F A+ +YD M   GV+P+ +T TS+LS CSQLAALEKGK+IH ++ +S  ET+E+++ ALLDMY+KCG V EA  +FN +P +D VSWT MI+AYGSHGQ  EAL  F EMQ+   KPDGVT LAVLSAC H GL+DEG  +F+QM + YGI+  IE YSCLID+LGRAGRL EAY ILQ+  E R++ +LLSTLF AC LHR+  LG  IA+LL+EK PDD STY +L N YAS + WD  K+VRLKMKE+G+RK PGCSWIE+N+K+  FF  D+SHPQ+E
Sbjct:   18 SLRQAKLVHQRILTVGLRSDVVLCKSLINVYFACKDHCSARLVFENIDIRSDVYIWNSLVSGYSKNSMFHDTLKVFKRLLNCPICVPDSFTYPNVIKAYGALGREFLGRMIHTVVVKSGHVCDVVVASSLVGMYAKFNLFEDSVQVFDEMPERDVASWNTVISSFYQRGDAEKALELFGRMERSDFEPNSVSITVAISACSRLLCLERGKEIHRKYLKKEFELDEYVNSALVDMYGRCDFLEMAREVFQQMRRKSLVAWNSMIRGYVARGDSKSCVELLNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFVHGYVIRSVVDADIYINCSLIDLYFKCGEVKLAETVFLKTQKDVVESWNVMISGYVSVGNWFKAVDVYDQMVSVGVQPDIVTFTSVLSTCSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNVKEASRIFNSIPKKDVVSWTVMISAYGSHGQPREALYHFDEMQKFGVKPDGVTFLAVLSACGHAGLIDEGVKYFSQMRSKYGIEASIEQYSCLIDILGRAGRLLEAYGILQQKPETRDNAELLSTLFCACCLHRDHLLGYTIAKLLVEKYPDDASTYTVLFNLYASGESWDAAKRVRLKMKEVGMRKKPGCSWIEMNEKVCHFFAEDRSHPQAE 673          

Query:  289 SVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISCYYQDGQAQKAMELFEKMRNSGF-TPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLH 1734
            S+L+ C     +   K++H  ++  G  SD+V+  SL+ +Y  C     A  +F+ +  R DV  WN+++S Y ++      +++F+++ N     P+S T   VI +   L     G  IH  ++K   V D  V S+LV MY K    + + +VF+++P ++V +WN++I+++   GD+   ++ F RM R    P   + +  + ACSR   L  GK IH   ++   E D Y+ S+L+D+Y     +  A+ VF++M + + V+WN MI GYV  GD    + + + M   G RP+  T+TSIL ACS+   L  GK +H  VI S  + +  +  +L+D+Y KCG V  A  VF +       SW  MI+ Y S G   +A+ ++ +M     +PD VT  +VLS CS +  +++G    +  I+   ++      S L+D+  + G + EA  I    S  ++DV   + + SA   H
Sbjct:    8 SLLRECTNTKSLRQAKLVHQRILTVGLRSDVVLCKSLINVYFACKDHCSARLVFENIDIRSDVYIWNSLVSGYSKNSMFHDTLKVFKRLLNCPICVPDSFTYPNVIKAYGALGREFLGRMIHTVVVKSGHVCDVVVASSLVGMYAKFNLFEDSVQVFDEMPERDVASWNTVISSFYQRGDAEKALELFGRMERSDFEPNSVSITVAISACSRLLCLERGKEIHRKYLKKEFELDEYVNSALVDMYGRCDFLEMAREVFQQMRRKSLVAWNSMIRGYVARGDSKSCVELLNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFVHGYVIRSVVDADIYINCSLIDLYFKCGEVKLAETVFLKTQKDVVESWNVMISGYVSVGNWFKAVDVYDQMVSVGVQPDIVTFTSVLSTCSQLAALEKGKQ-IHLSISESRLETDELLLSALLDMYSKCGNVKEASRIF--NSIPKKDVVSWTVMISAYGSH 488          

Query:  577 SVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGDSISCIQFFRR-MNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIE---HYSC-LIDLLGRAGRLNEAYEILQRTSE 1680
            S  L +++  C     L +   +H+ ++   L  D  +  +L+++Y  C     A+ VFE I I+ +V  WNS+++ YS        ++ F+R +N     P   T+ +++ A     +   G+ IH  ++++    D+ + SSL+ +Y        +  VF++MP+ +  SWN +IS + + GD   AL ++  M+ +   PN++++T  +SACS+L  LE+GKEIHR  +  EFE +E +  AL+DMY +C  ++ A  VF ++  +  V+W SMI  Y + G +   ++L   M     +P   TL ++L ACS    +  G     + +  Y I+  ++   + +C LIDL  + G +  A  +  +T +
Sbjct:    3 SSKLLSLLRECTNTKSLRQAKLVHQRILTVGLRSDVVLCKSLINVYFACKDHCSARLVFENIDIRSDVYIWNSLVSGYSKNSMFHDTLKVFKRLLNCPICVPDSFTYPNVIKAYGALGREFLGRMIHTVVVKSGHVCDVVVASSLVGMYAKFNLFEDSVQVFDEMPERDVASWNTVISSFYQRGDAEKALELFGRMERSDFEPNSVSITVAISACSRLLCLERGKEIHRKYLKKEFELDEYVNSALVDMYGRCDFLEMAREVFQQMRRKSLVAWNSMIRGYVARGDSKSCVELLNRMIIEGTRPSQTTLTSILMACSRSRNLLHG-----KFVHGYVIRSVVDADIYINCSLIDLYFKCGEVKLAETVFLKTQK 371          

Query:  187 MTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGR 1632
            M  +TKN M+ EALELF+ LL+YPY+ PDS+TYPSVLKACG LG+  +G+MIH HLIK+GFV DIVVASSLV ++AKCN+F  AI+LFDEMPERDVACWNTVISCYYQDG+A+KA+E+F KMR+SGF PNSVTLTTVISSCARL DLERG +IH+E++++ +VLD FV SALVDMYGK GCLD+AK++FEQ+P K +VAWNS+IA YS   DS  CI+ F RMN EGT PT+TT SSILLACSR+A L HG+FIH + +RN ++ DI++ S LI+LYF  G V SA+N+F  +PK N V WNVMISGYV +GDY  AL +YD+MK A V+P+A+T +SILSACSQLAALEKGKEIH  +  ++ ETNEI+MGALLDMYAKCGAVDEAL+VFN+LP RD +SWTS+I+AYGSHGQALEAL+LF E+QQS A PD VT LAVLSACSH GLVD+G ++FNQMITNYGIKP +EHYSCLIDLLGR
Sbjct:    1 MAAYTKNCMYTEALELFDRLLQYPYLQPDSFTYPSVLKACGGLGRYDYGRMIHTHLIKSGFVFDIVVASSLVSLHAKCNLFGYAIQLFDEMPERDVACWNTVISCYYQDGKAEKALEMFGKMRDSGFEPNSVTLTTVISSCARLLDLERGKEIHREVMQNGMVLDGFVGSALVDMYGKFGCLDLAKDIFEQMPKKTLVAWNSLIAGYSSAADSKECIELFWRMNMEGTKPTVTTLSSILLACSRAAHLQHGRFIHGYAVRNRVQLDIFVSSGLIELYFKCGKVQSAENIFYMLPKANVVLWNVMISGYVTIGDYVKALDMYDEMKIASVKPDAVTFSSILSACSQLAALEKGKEIHNCITKNDLETNEIVMGALLDMYAKCGAVDEALSVFNKLPERDLLSWTSIISAYGSHGQALEALRLFEELQQSKASPDAVTFLAVLSACSHAGLVDKGYYYFNQMITNYGIKPGLEHYSCLIDLLGR 482          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNI-IEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTN 1077
            L++GK IH++++  G+  D  +   L++ Y      D AK +F+ +   + ++ WN ++ G++      E +ELF   +      P   T  S+L AC     +  G+ IH + ++     DI V+S L+ +Y KC     A  +F  +P+ +V  WN +IS Y   G   KA++++++M+ +   P++VT ++++S+C++L  LE+G +IH  + K+ L  +  V  AL+DMY KCG +D A  VF ++P +++++W S+I+AY   G ++  ++ F  + +   SP   TF ++L ACS +  +  G +    MI N  I+  +  YS LIDL    G +        ++P  N
Sbjct:  147 LERGKEIHREVMQNGMVLDGFVGSALVDMYGKFGCLDLAKDIFEQMPKKTLVA-WNSLIAGYSSAADSKECIELFWR-MNMEGTKPTVTTLSSILLACSRAAHLQHGRFIHGYAVRNRVQLDIFVSSGLIELYFKCGKVQSAENIFYMLPKANVVLWNVMISGYVTIGDYVKALDMYDEMKIASVKPDAVTFSSILSACSQLAALEKGKEIHNCITKNDLETNEIVMGALLDMYAKCGAVDEALSVFNKLPERDLLSWTSIISAYGSHGQALEALRLFEELQQSKASPDAVTFLAVLSACSHAGLVDKGYYYFNQMITNYGIKPGLEHYSCLIDLL---GRIQEQSQELNEIPCPN 497          

Query:  172 LWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            +W   + G+ KN  + +AL L+  + R   I PD   + SV+KACG+   +  G+ +H  +I  GF SD++V ++L  MY KC   + A ++FD MP+RDV  WN +I+ Y Q+GQ  +A+ LF +M+ +G  PNS TL +V+  CA L  LE+G +IH   I+  +  D  V + LV+MY KCG ++ A ++FE++PI++V +WN++I  YS+       + FF RM   G  P   T  S+L AC+    L  G+ IH + IR+  E++  + ++L+++Y   G+V+SA  +FE+MPK N V+WN +ISGY + G    ALA++ +M+  G++P++  + S+L AC+   ALE+GK+IH   I S FE+N ++   L+D+YAKCG V+ A  +F R+P +D VSWT+MI AYG HG   +AL LF +MQ++  K D +   A+L+ACSH GLVD+G  +F  M ++YG+ P++EHY+CL+DLLGRAG L+EA  I++  S +  D ++   L  ACR+H N++LG + A+ L E +PD+   Y++LSN YA  ++W++V K+R  MKE G++K PGCS + +++ +  F VGD++HPQSE
Sbjct:   87 VWKETIIGYVKNGFWNKALRLYYQMQRTG-INPDKLVFLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQVFDRMPKRDVVSWNAIIAGYSQNGQPYEALALFSEMQVNGIKPNSSTLVSVMPVCAHLLALEQGKQIHCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPIRDVASWNAIIGGYSLNSQHHEALAFFNRMQVRGIKPNSITMVSVLPACAHLFALEQGQQIHGYAIRSGFESNDVVGNALVNMYAKCGNVNSAYKLFERMPKKNVVAWNAIISGYSQHGHPHEALALFIEMQAQGIKPDSFAIVSVLPACAHFLALEQGKQIHGYTIRSGFESNVVVGTGLVDIYAKCGNVNTAQKLFERMPEQDVVSWTTMILAYGIHGHGEDALALFSKMQETGTKLDHIAFTAILTACSHAGLVDQGLQYFQCMKSDYGLAPKLEHYACLVDLLGRAGHLDEANGIIKNMS-LEPDANVWGALLGACRIHCNIELGEQAAKHLFELDPDNAGYYVLLSNIYAEAQRWEDVAKLRKMMKEKGVKKQPGCSVVAVHRDVQTFLVGDRTHPQSE 686          

Query:  751 FEQIPIKN-VVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHY----SCLIDLLGRAGRLNEAYEILQR 1671
            F Q  I+N  V W   I  Y   G     ++ + +M R G +P    F S++ AC   + L  G+ +H  +I    E+D+ + ++L  +Y   GS+ +A+ VF++MPK + VSWN +I+GY + G  + ALA++ +M+  G++PN+ T+ S++  C+ L ALE+GK+IH   I S  E++ +++  L++MYAKCG V+ A  +F R+P RD  SW ++I  Y  + Q  EAL  F  MQ    KP+ +T+++VL AC+H+  +++G     Q I  Y I+   E      + L+++  + G +N AY++ +R
Sbjct:   76 FTQTDIRNNAVVWKETIIGYVKNGFWNKALRLYYQMQRTGINPDKLVFLSVIKACGSQSDLQAGRKVHEDIIARGFESDVIVGTALASMYTKCGSLENARQVFDRMPKRDVVSWNAIIAGYSQNGQPYEALALFSEMQVNGIKPNSSTLVSVMPVCAHLLALEQGKQIHCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMPIRDVASWNAIIGGYSLNSQHHEALAFFNRMQVRGIKPNSITMVSVLPACAHLFALEQG-----QQIHGYAIRSGFESNDVVGNALVNMYAKCGNVNSAYKLFER 382          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHG-KFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKM 1065
            +L+QGK IH   +  G+++D  +   L+N Y  C   ++A  +F+ +     ++ WN ++ G++ N    EAL  F + ++   I P+S T  SVL AC  L  +  G+ IH + I++GF S+ VV ++LV MYAKC   + A +LF+ MP+++V  WN +IS Y Q G   +A+ LF +M+  G  P+S  + +V+ +CA    LE+G +IH   I+     +  V + LVD+Y KCG ++ A+++FE++P ++VV+W +MI AY + G     +  F +M   GT      F++IL ACS +  +  G ++         +   +  Y+ L+DL   +G +  A  + + M
Sbjct:  236 ALEQGKQIHCYAIRSGIESDVLVVNGLVNMYAKCGNVNTAHKLFERMP-IRDVASWNAIIGGYSLNSQHHEALAFF-NRMQVRGIKPNSITMVSVLPACAHLFALEQGQQIHGYAIRSGFESNDVVGNALVNMYAKCGNVNSAYKLFERMPKKNVVAWNAIISGYSQHGHPHEALALFIEMQAQGIKPDSFAIVSVLPACAHFLALEQGKQIHGYTIRSGFESNVVVGTGLVDIYAKCGNVNTAQKLFERMPEQDVVSWTTMILAYGIHGHGEDALALFSKMQETGTKLDHIAFTAILTACSHAGLVDQGLQYFQCMKSDYGLAPKLEHYACLVDLLGRAGHLDEANGIIKNM 586          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHP 1968
            S++ G+ IH  + +  ++ D  L   L+  Y +C      + +F  + N   + LWN +M G+ K   F E+L LF+ + R   +  +SYT+  V+K   A G V  G+ +H +L + GF S   V +SL+  Y K    + A +LFDE+ +RDV  WN++IS Y  +G ++K ++LFE+M   G   +  T+ +V++ C+    L  G  +H   IK     +  + + L+DMY K G L+ A +VFE +  ++VV+W SMIA Y+  G S   ++ F  M +EG SP + T ++IL AC+ +  L +GK +H ++  N +++D+++ ++L+D+Y   GS+  A +VF +M   + VSWN MI GY K      AL ++ +M +   +PN+IT+  IL AC+ LAALE+G+EIH  ++ + F  +  +  AL+DMY KCGA+  A  +F+ +P +D VSWT MI  YG HG   EA+  F EM+ S  +PD V+ +++L ACSH GL+DEG  FFN M  N  I+P+ EHY+C++DLL RAG L++AY+ + +   I  D  +   L   CR++ ++ L  K+A  + E  P++   Y++L+N YA  +KW+EVKK+R ++   GLRKNPGCSWIEI  K+H F  GD SHP
Sbjct:  116 SIQDGRRIHSIIQSNDVEVDGVLGSKLVFMYVTCGDLREGRRIFDKVAN-EKVFLWNLLMNGYAKIGNFRESLSLFKRM-RELGVKMNSYTFSCVMKCYAASGSVEEGEGVHAYLSRLGFGSYNTVVNSLIAFYFKIRRVESARKLFDELGDRDVISWNSMISGYVSNGLSEKGLDLFEQMLLLGINTDLATMVSVVAGCSNTGMLLLGRALHGYAIKASFGKELTLNNCLLDMYSKSGNLNSAIQVFETMGERSVVSWTSMIAGYAREGLSDMSVRLFHEMEKEGISPDIFTITTILHACACTGLLENGKDVHNYIKENKMQSDLFVSNALMDMYAKCGSMGDAHSVFSEMQVKDIVSWNTMIGGYSKNSLPNEALNLFVEM-QYNSKPNSITMACILPACASLAALERGQEIHGHILRNGFSLDRHVANALVDMYLKCGALGLARLLFDMIPEKDLVSWTVMIAGYGMHGYGSEAIAAFNEMRNSGIEPDEVSFISILYACSHSGLLDEGWGFFNMMRNNCCIEPKSEHYACIVDLLARAGNLSKAYKFI-KMMPIEPDATIWGALLCGCRIYHDVKLAEKVAEHVFELEPENTGYYVLLANIYAEAEKWEEVKKLRERIGRRGLRKNPGCSWIEIKGKVHIFVTGDSSHP 764          

Query:   94 NFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEA 1653
            N Y SC    ++ L  ++I+    I+ +N  +  F +      A+EL     + P    +  TY SVL+ C  L  +  G+ IH+ +       D V+ S LV MY  C       R+FD++    V  WN +++ Y + G  ++++ LF++MR  G   NS T + V+   A    +E G  +H  L +      + V ++L+  Y K   ++ A+++F+++  ++V++WNSMI+ Y   G S   +  F +M   G +  L T  S++  CS +  LL G+ +H + I+     ++ + + L+D+Y  SG+++SA  VFE M + + VSW  MI+GY + G    ++ ++ +M++ G+ P+  T+T+IL AC+    LE GK++H  + +++ +++  +  AL+DMYAKCG++ +A +VF+ +  +D VSW +MI  Y  +    EAL LF EMQ  N+KP+ +T+  +L AC+ +  ++ G      ++ N G        + L+D+  + G L  A
Sbjct:   46 NLYHSCATIGTSVLPSETID--CKITDYNIEICRFCELGNLRRAMELIN---QSPKPDLELRTYCSVLQLCADLKSIQDGRRIHSIIQSNDVEVDGVLGSKLVFMYVTCGDLREGRRIFDKVANEKVFLWNLLMNGYAKIGNFRESLSLFKRMRELGVKMNSYTFSCVMKCYAASGSVEEGEGVHAYLSRLGFGSYNTVVNSLIAFYFKIRRVESARKLFDELGDRDVISWNSMISGYVSNGLSEKGLDLFEQMLLLGINTDLATMVSVVAGCSNTGMLLLGRALHGYAIKASFGKELTLNNCLLDMYSKSGNLNSAIQVFETMGERSVVSWTSMIAGYAREGLSDMSVRLFHEMEKEGISPDIFTITTILHACACTGLLENGKDVHNYIKENKMQSDLFVSNALMDMYAKCGSMGDAHSVFSEMQVKDIVSWNTMIGGYSKNSLPNEALNLFVEMQY-NSKPNSITMACILPACASLAALERGQEIHGHILRN-GFSLDRHVANALVDMYLKCGALGLA 558          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            ++ +G+ ++  +L  G   D  +   LIN +  C     A  VF ++     ++ W  ++TG  ++  F +A  LF+ +     + PD   + S+L+AC     +  GK +H  + + G+ ++I V ++++ MY KC   + A+ +FD +  R+V  W  +I+ + Q G+  +A   F KM  SG  PN VT  +++ +C+    L+RG +I   +I+     D  V +AL+ MY KCG L  A  VFE+I  +NVVAWN+MI AY       + +  F+ + +EG  P  +TF+SIL  C  S  L  GK++H  +++  +E+D+++ ++L+ ++   G + SAKN+F  MPK + VSWN +I+G+V+ G    A   +  M+E+G++P+ IT T +L+AC+   AL +G+ +H  + ++ F+ + ++   L+ MY KCG++++A  VF++LP ++  SWTSMIT Y  HG+  EAL+LF +MQQ   KPD +T +  LSAC+H GL++EG H F Q +  + I+PR+EHY C++DL GRAG LNEA E + +  ++  D  +   L  AC++H N++L  K A+  +E +P+D+  +++LSN YA+   W EV K+R  M + G+ K PG SWIE++ K+H F+  DK+HPQ+E
Sbjct:  226 NVDKGRELYNLILKAGWDTDLFVGTALINMHIKCGDIGDATKVFDNLPTRDLVT-WTSMITGLARHGRFKQACNLFQRM-EEEGVQPDKVAFVSLLRACNHPEALEQGKKVHARMKEVGWDTEIYVGTAILSMYTKCGSMEDALEVFDLVKGRNVVSWTAMIAGFAQHGRIDEAFLFFNKMIESGIEPNRVTFMSILGACSSPSALKRGQQIQDHIIEAGYGSDDRVRTALLSMYAKCGSLKDAHRVFEKISKQNVVAWNAMITAYVQHEQYDNALATFQALLKEGIKPNSSTFTSILNVCKSSDSLELGKWVHFLIMKAGLESDLHVSNALVSMFVNCGDLMSAKNLFNDMPKRDLVSWNTIIAGFVQHGKNQVAFDYFKMMQESGIKPDKITFTGLLNACASPEALTEGRRLHALITEAAFDCDVLVGTGLISMYTKCGSIEDAHQVFHKLPKKNVYSWTSMITGYAQHGRGKEALELFYQMQQEGVKPDWITFVGALSACAHAGLIEEGLHHF-QSMKEFNIEPRMEHYGCMVDLFGRAGLLNEAVEFIIK-MQVEPDSRVWGALLGACQVHLNVELAEKAAQKKLELDPNDNGVFVILSNIYAAAGMWKEVAKMRKVMLDRGVVKKPGQSWIEVDGKVHTFYSDDKTHPQTE 877          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            +L  G+ I+  +   G+Q D  +   LIN Y  C    SAK +F  +      S WN ++ G+ ++ ++ EA +L E +++   + PD  T+ S+L AC     V  G+ ++N ++K G+ +D+ V ++L+ M+ KC     A ++FD +P RD+  W ++I+   + G+ ++A  LF++M   G  P+ V   +++ +C     LE+G K+H  + +     + +V +A++ MY KCG ++ A EVF+ +  +NVV+W +MIA ++  G       FF +M   G  P   TF SIL ACS  + L  G+ I   +I     +D  + ++L+ +Y   GS+  A  VFEK+ K N V+WN MI+ YV+   Y  ALA +  + + G++PN+ T TSIL+ C    +LE GK +H  ++ +  E++  +  AL+ M+  CG +  A N+FN +P RD VSW ++I  +  HG+   A   F  MQ+S  KPD +T   +L+AC+    + EG    + +IT       +   + LI +  + G + +A+++  +
Sbjct:  125 NLGDGERIYNHIKKSGVQPDIFMWNTLINMYAKCGNTISAKQIFDDMREKDVYS-WNLLLGGYVQHGLYEEAFKLHEQMVQ-DSVKPDKRTFVSMLNACADARNVDKGRELYNLILKAGWDTDLFVGTALINMHIKCGDIGDATKVFDNLPTRDLVTWTSMITGLARHGRFKQACNLFQRMEEEGVQPDKVAFVSLLRACNHPEALEQGKKVHARMKEVGWDTEIYVGTAILSMYTKCGSMEDALEVFDLVKGRNVVSWTAMIAGFAQHGRIDEAFLFFNKMIESGIEPNRVTFMSILGACSSPSALKRGQQIQDHIIEAGYGSDDRVRTALLSMYAKCGSLKDAHRVFEKISKQNVVAWNAMITAYVQHEQYDNALATFQALLKEGIKPNSSTFTSILNVCKSSDSLELGKWVHFLIMKAGLESDLHVSNALVSMFVNCGDLMSAKNLFNDMPKRDLVSWNTIIAGFVQHGKNQVAFDYFKMMQESGIKPDKITFTGLLNACASPEALTEG-RRLHALITEAAFDCDVLVGTGLISMYTKCGSIEDAHQVFHK 675          

Query:  178 NGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEG--CHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKN-PDDHSTYIMLSNTYASVKKWDEVKKVRLKMKE 1881
            N V+   +K   F EA+++ E +    +I     TY ++L+ C     +G G+ I+NH+ K+G   DI + ++L+ MYAKC     A ++FD+M E+DV  WN ++  Y Q G  ++A +L E+M      P+  T  +++++CA   ++++G +++  ++K     D FV +AL++M+ KCG +  A +VF+ +P +++V W SMI   +  G        F+RM  EG  P    F S+L AC+    L  GK +HA M     + +IY+ ++++ +Y   GS+  A  VF+ +   N VSW  MI+G+ + G    A   ++ M E+G+ PN +T  SIL ACS  +AL++G++I   +I++ + +++ +  ALL MYAKCG++ +A  VF ++  ++ V+W +MITAY  H Q   AL  F  + +   KP+  T  ++L+ C     ++ G   HF   +I   G++  +   + L+ +    G L  A  +       + D+   +T+ +    H    +     +++ E     D  T+  L N  AS +   E +++   + E
Sbjct:   79 NAVLNRLSKAGQFNEAMQVLERV-DSSHIQIYRQTYSALLQLCIKFKNLGDGERIYNHIKKSGVQPDIFMWNTLINMYAKCGNTISAKQIFDDMREKDVYSWNLLLGGYVQHGLYEEAFKLHEQMVQDSVKPDKRTFVSMLNACADARNVDKGRELYNLILKAGWDTDLFVGTALINMHIKCGDIGDATKVFDNLPTRDLVTWTSMITGLARHGRFKQACNLFQRMEEEGVQPDKVAFVSLLRACNHPEALEQGKKVHARMKEVGWDTEIYVGTAILSMYTKCGSMEDALEVFDLVKGRNVVSWTAMIAGFAQHGRIDEAFLFFNKMIESGIEPNRVTFMSILGACSSPSALKRGQQIQDHIIEAGYGSDDRVRTALLSMYAKCGSLKDAHRVFEKISKQNVVAWNAMITAYVQHEQYDNALATFQALLKEGIKPNSSTFTSILNVCKSSDSLELGKWVHF---LIMKAGLESDLHVSNALVSMFVNCGDLMSAKNLFNDMP--KRDLVSWNTIIAGFVQHGKNQVAFDYFKMMQESGIKPDKITFTGLLNACASPEALTEGRRLHALITE 643          

Query:  466 RDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMI-TNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKN-PDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKN 1899
            +D    N V++   + GQ  +AM++ E++ +S       T + ++  C +  +L  G +I+  + K  +  D F+ + L++MY KCG    AK++F+ +  K+V +WN ++  Y   G      +   +M ++   P   TF S+L AC+ +  +  G+ ++  +++   + D+++ ++LI+++   G +  A  VF+ +P  + V+W  MI+G  + G +  A  ++  M+E GV+P+ +   S+L AC+   ALE+GK++H  + +  ++T   +  A+L MY KCG++++AL VF+ +  R+ VSWT+MI  +  HG+  EA   F +M +S  +P+ VT +++L ACS    +  G    + +I   YG   R+   + L+ +  + G L +A+ + ++ S  +++V   + + +A   H   D  +   + L+++    + ST+  + N   S    +  K V   + + GL  +
Sbjct:   73 KDTQKANAVLNRLSKAGQFNEAMQVLERVDSSHIQIYRQTYSALLQLCIKFKNLGDGERIYNHIKKSGVQPDIFMWNTLINMYAKCGNTISAKQIFDDMREKDVYSWNLLLGGYVQHGLYEEAFKLHEQMVQDSVKPDKRTFVSMLNACADARNVDKGRELYNLILKAGWDTDLFVGTALINMHIKCGDIGDATKVFDNLPTRDLVTWTSMITGLARHGRFKQACNLFQRMEEEGVQPDKVAFVSLLRACNHPEALEQGKKVHARMKEVGWDTEIYVGTAILSMYTKCGSMEDALEVFDLVKGRNVVSWTAMIAGFAQHGRIDEAFLFFNKMIESGIEPNRVTFMSILGACSSPSALKRGQQIQDHIIEAGYGSDDRVR--TALLSMYAKCGSLKDAHRVFEKIS--KQNVVAWNAMITAYVQHEQYDNALATFQALLKEGIKPNSSTFTSILNVCKSSDSLELGKWVHFLIMKAGLESD 548          

Query:  766 IKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEI 1662
            IK+    N+++   S  G     +Q   R++         T+S++L  C +   L  G+ I+  + ++ ++ DI+++++LI++Y   G+  SAK +F+ M + +  SWN+++ GYV+ G Y  A  +++ M +  V+P+  T  S+L+AC+    ++KG+E++  ++ + ++T+  +  AL++M+ KCG + +A  VF+ LP RD V+WTSMIT    HG+  +A  LF  M++   +PD V  +++L AC+H   +++G     +M    G    I   + ++ +  + G + +A E+
Sbjct:   72 IKDTQKANAVLNRLSKAGQFNEAMQVLERVDSSHIQIYRQTYSALLQLCIKFKNLGDGERIYNHIKKSGVQPDIFMWNTLINMYAKCGNTISAKQIFDDMREKDVYSWNLLLGGYVQHGLYEEAFKLHEQMVQDSVKPDKRTFVSMLNACADARNVDKGRELYNLILKAGWDTDLFVGTALINMHIKCGDIGDATKVFDNLPTRDLVTWTSMITGLARHGRFKQACNLFQRMEEEGVQPDKVAFVSLLRACNHPEALEQGKKVHARM-KEVGWDTEIYVGTAILSMYTKCGSMEDALEV 369          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSV 813
            ++SL+ GK +H  ++  GL++D  +   L++ + +C    SAK +F  +     +S WN ++ GF ++     A + F+ +++   I PD  T+  +L AC +   +  G+ +H  + +  F  D++V + L+ MY KC   + A ++F ++P+++V  W ++I+ Y Q G+ ++A+ELF +M+  G  P+ +T    +S+CA    +E G+   + + +  +         +VD++G+ G L+ A E   ++ ++ +   W +++ A  V
Sbjct:  527 SDSLELGKWVHFLIMKAGLESDLHVSNALVSMFVNCGDLMSAKNLFNDMPKRDLVS-WNTIIAGFVQHGKNQVAFDYFK-MMQESGIKPDKITFTGLLNACASPEALTEGRRLHALITEAAFDCDVLVGTGLISMYTKCGSIEDAHQVFHKLPKKNVYSWTSMITGYAQHGRGKEALELFYQMQQEGVKPDWITFVGALSACAHAGLIEEGLHHFQSMKEFNIEPRMEHYGCMVDLFGRAGLLNEAVEFIIKMQVEPDSRVWGALLGACQV 795          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL++ KL+HQ++LTLGL+ D  LCK+LIN YF+C    SA+ VF++ +  S + +WN +M+G++KN MF + LE+F+ LL      PDS+T+P+V+KA GALG+   G+MIH  ++K+G+V D+VVASSLV MYAK N+F+ ++++FDEMPERDVA WNTVISC+YQ G+A+KA+ELF +M +SGF PNSV+LT  IS+C+RL  LERG +IH++ +K    LD +V SALVDMYGKC CL++A+EVF+++P K++VAWNSMI  Y   GDS SC++   RM  EGT P+ TT +SIL+ACSRS  LLHGKFIH ++IR+++ ADIY+  SLIDLYF  G  + A+ VF K  K    SWNVMIS Y+ VG++F A+ +YD M   GV+P+ +T TS+L ACSQLAALEKGK+IH ++ +S  ET+E+++ ALLDMY+KCG   EA  +FN +P +D VSWT MI+AYGSHGQ  EAL  F EMQ+   KPDGVTLLAVLSAC H GL+DEG  FF+QM + YGI+P IEHYSC+ID+LGRAGRL EAYEI+Q+T E  ++ +LLSTLFSAC LH    LG +IARLL+E  PDD STY++L N YAS + WD  ++VRLKMKE+GLRK PGCSWIE++ K+  FF  D+SH ++E
Sbjct:   19 SLRRIKLVHQRILTLGLRRDVVLCKSLINVYFTCKDHCSARHVFENFDIRSDVYIWNSLMSGYSKNSMFHDTLEVFKRLLNCSICVPDSFTFPNVIKAYGALGREFLGRMIHTLVVKSGYVCDVVVASSLVGMYAKFNLFENSLQVFDEMPERDVASWNTVISCFYQSGEAEKALELFGRMESSGFEPNSVSLTVAISACSRLLWLERGKEIHRKCVKKGFELDEYVNSALVDMYGKCDCLEVAREVFQKMPRKSLVAWNSMIKGYVAKGDSKSCVEILNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFIHGYVIRSVVNADIYVNCSLIDLYFKCGEANLAETVFSKTQKDVAESWNVMISSYISVGNWFKAVEVYDQMVSVGVKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQMRSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTPETSDNAELLSTLFSACCLHLEHSLGDRIARLLVENYPDDASTYMVLFNLYASGESWDAARRVRLKMKEMGLRKKPGCSWIEMSDKVCHFFAEDRSHLRAE 674          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVT--SALVDMYGKCGCLDMAKEVFEQIP 765
            + +L  GK IH  ++   +  D  +  +LI+ YF C   + A+ VF   +   + S WN +++ +     + +A+E+++ ++    + PD  T+ SVL AC  L  +  GK IH  + ++   +D ++ S+L+ MY+KC     A R+F+ +P++DV  W  +IS Y   GQ ++A+  F++M+  G  P+ VTL  V+S+C     ++ G+K   ++ + +  ++  +   S ++D+ G+ G L  A E+ +Q P
Sbjct:  322 SRNLLHGKFIHGYVIRSVVNADIYVNCSLIDLYFKCGEANLAETVFSKTQKDVAES-WNVMISSYISVGNWFKAVEVYDQMVSVG-VKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQM-RSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTP 574          

Query:    7 NSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            +SLK+ + I   +   GL  +      L++ +      D A  VF+ I++  ++ L++ ++ GF K     +AL+ F  + RY  + P  Y +  +LK CG   ++  GK IH  L+K+GF  D+   + L  MYAKC   + A ++FD MPERD+  WNT+++ Y Q+G A+ A+E+ + M      P+ +T+ +V+ + + L  +  G +IH   ++        +++ALVDMY KCG L+ A+++F+ +  +NVV+WNSMI AY    +    +  F++M  EG  PT  +    L AC+    L  G+FIH   +   ++ ++ + +SLI +Y     V +A ++F K+     VSWN MI G+ + G    AL  +  M+   V+P+  T  S+++A ++L+     K IH  V+ S  + N  +  AL+DMYAKCGA+  A  +F+ +  R   +W +MI  YG+HG    AL+LF EMQ+   KP+GVT L+V+SACSH GLV+ G   F  M  NY I+  ++HY  ++DLLGRAGRLNEA++ + +   ++  V++   +  AC++H+N++   K A  L E NPDD   +++L+N Y +   W++V +VR+ M   GLRK PGCS +EI  ++H FF G  +HP S+
Sbjct:   48 SSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNV-LYHTMLKGFAKVSDLDKALQFFVRM-RYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQ-MPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSK 701          

Query:  904 LACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEI 1662
            L   R + L   + I   + +N +  + +  + L+ L+   GSV  A  VFE +     V ++ M+ G+ KV D   AL  +  M+   V P     T +L  C   A L  GKEIH  ++ S F  +   M  L +MYAKC  V+EA  VF+R+P RD VSW +++  Y  +G A  AL++   M + N KP  +T+++VL A S + L+  G       + + G    +   + L+D+  + G L  A ++
Sbjct:   42 LLLERCSSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRS-GFDSLVNISTALVDMYAKCGSLETARQL 293          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSA-KLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNS-GFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNRE-----------------------------------GTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEA-------DIYIYSSLIDLYFVSGSVSSAKNVFEKM-PKT-NTVSWNVMISGYVKVGDYFGALAIYDDM--KEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMG-ALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            ++ Q KLIHQK+L+ G+     L  +LI+ Y S      A  L+ +   + + +  WN ++  +  N    + L LF  L+      PD+YT+P V KACG +  V  G+  H   + TGF+S++ V ++LV MY++C     A ++FDEM   DV  WN++I  Y + G+ + A+E+F +M N  G  P+++TL  V+  CA L     G ++H   +  +++ + FV + LVDMY KCG +D A  VF  + +K+VV+WN+M+A YS  G     ++ F +M  E                                   G  P   T  S+L  C+    L+HGK IH + I+  I+        +  + + LID+Y     V +A+ +F+ + PK  + V+W VMI GY + GD   AL +  +M  ++   RPNA T++  L AC+ LAAL  GK+IH   + ++     + +   L+DMYAKCG++ +A  VF+ +  ++ V+WTS++T YG HG   EAL +F EM++   K DGVTLL VL ACSH G++D+G  +FN+M T +G+ P  EHY+CL+DLLGRAGRLN A  +++        V  ++ L S CR+H  ++LG   A  + E   +   +Y +LSN YA+  +W +V ++R  M+  G++K PGCSW+E  K    FFVGDK+HP ++
Sbjct:   40 TISQVKLIHQKLLSFGILT-LNLTSHLISTYISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLF-GLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAYALRNQQNAVPLFVSNCLIDMYAKCGSISDARLVFDNMMAKNEVTWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVLYACSHSGMIDQGMEYFNRMKTVFGVSPGPEHYACLVDLLGRAGRLNAALRLIEEMPMEPPPVVWVAFL-SCCRIHGKVELGEYAAEKITELASNHDGSYTLLSNLYANAGRWKDVTRIRSLMRHKGVKKRPGCSWVEGIKGTTTFFVGDKTHPHAK 741          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDM-KEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            + SLK GK +   +   G   D  L   L   Y +C     A  VF  ++   ++  WN +M    K+  F  ++ LF+ ++    +  DSYT+  V K+  +L  V  G+ +H  ++K+GF     V +SLV  Y K    D A ++FDEM ERDV  WN++I+ Y  +G A+K + +F +M  SG   +  T+ +V + CA    +  G  +H   +K     +    + L+DMY KCG LD AK VF ++  ++VV++ SMIA Y+  G +   ++ F  M  EG SP + T +++L  C+R   L  GK +H ++  N +  DI++ ++L+D+Y   GS+  A+ VF +M   + +SWN +I GY K      AL++++ + +E    P+  TV  +L AC+ L+A +KG+EIH  ++ + + ++  +  +L+DMYAKCGA+  A  +F+ + ++D VSWT MI  YG HG   EA+ LF +M+Q+  + D ++ +++L ACSH GLVDEG  FFN M     I+P +EHY+C++D+L R G L +AY  ++    I  D  +   L   CR+H ++ L  K+A  + E  P++   Y++++N YA  +KW++VK++R ++ + GLRKNPGCSWIEI  +++ F  GD S+P++E
Sbjct:  107 SKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKAL-FWNILMNELAKSGDFSGSIGLFKKMMSSG-VEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDRHVANSLVDMYAKCGALLLAHMLFDDIASKDLVSWTVMIAGYGMHGFGKEAIALFNQMRQAGIEADEISFVSLLYACSHSGLVDEGWRFFNIMRHECKIEPTVEHYACIVDMLARTGDLIKAYRFIE-NMPIPPDATIWGALLCGCRIHHDVKLAEKVAEKVFELEPENTGYYVLMANIYAEAEKWEQVKRLRKRIGQRGLRKNPGCSWIEIKGRVNIFVAGDSSNPETE 762          

Query:  271 DSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFG-EMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRL 1644
            D  T  SVL+ C     +  GK + N +   GFV D  + S L  MY  C     A R+FDE+       WN +++   + G    ++ LF+KM +SG   +S T + V  S + L  +  G ++H  ++K      + V ++LV  Y K   +D A++VF+++  ++V++WNS+I  Y   G +   +  F +M   G    L T  S+   C+ S  +  G+ +H+  ++     +    ++L+D+Y   G + SAK VF +M   + VS+  MI+GY + G    A+ ++++M+E G+ P+  TVT++L+ C++   L++GK +H  + +++   +  +  AL+DMYAKCG++ EA  VF+ +  +D +SW ++I  Y  +  A EAL LF   +++    PD  T+  VL AC+ +   D+G      ++ N     R    + L+D+  + G L
Sbjct:   93 DPRTLCSVLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDR-HVANSLVDMYAKCGAL 550          

Query:   16 KQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            + G L+++++L +G ++D  +   L++ Y        A+ VF  +     +S WN +++G++ +  + EALE++  L +  +I PDS+T  SVL A G L  V  G+ +H   +K+G  S +VV + LV MY K      A R+FDEM  RD   +NT+I  Y +    ++++ +F +  +  F P+ +T+++V+ +C  L DL     I+  ++K   VL+S V + L+D+Y KCG +  A++VF  +  K+ V+WNS+I+ Y  +GD +  ++ F+ M          T+  ++   +R A L  GK +H+  I++ I  D+ + ++LID+Y   G V  +  +F  M   +TV+WN +IS  V+ GD+   L +   M+++ V P+  T    L  C+ LAA   GKEIH  ++   +E+   +  AL++MY+KCG ++ +  VF R+  RD V+WT MI AYG +G+  +AL+ F +M++S   PD V  +A++ ACSH GLVDEG   F +M T+Y I P IEHY+C++DLL R+ ++++A E +Q    I+ D  + +++  ACR   +++   +++R +IE NPDD    I+ SN YA+++KWD+V  +R  +K+  + KNPG SWIE+ K +H F  GD S PQSE
Sbjct:  123 EMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVS-WNSLISGYSSHGYYEEALEIYHEL-KNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIVPDSVVFIAIIYACSHSGLVDEGLACFEKMKTHYKIDPMIEHYACVVDLLSRSQKISKAEEFIQ-AMPIKPDASIWASVLRACRTSGDMETAERVSRRIIELNPDDPGYSILASNAYAALRKWDKVSLIRKSLKDKHITKNPGYSWIEVGKNVHVFSSGDDSAPQSE 772          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDV 1695
            +++L + + IH  +++LGL +       LI+ Y       S+  VF+ +    ++ LWN ++  F+KN +F EALE F   LR   + PD YT+PSV+KAC  L     G +++  ++  GF SD+ V ++LV MY++  +   A ++FDEMP RD+  WN++IS Y   G  ++A+E++ +++NS   P+S T+++V+ +   L  +++G  +H   +K  +     V + LV MY K      A+ VF+++ +++ V++N+MI  Y         ++ F   N +   P L T SS+L AC     L   K+I+ +M++     +  + + LID+Y   G + +A++VF  M   +TVSWN +ISGY++ GD   A+ ++  M     + + IT   ++S  ++LA L+ GK +H   I S    +  +  AL+DMYAKCG V ++L +F+ +   D V+W ++I+A    G     L++  +M++S   PD  T L  L  C+ +     G    +  +  +G +  ++  + LI++  + G L  +  + +R S  R DV
Sbjct:   17 SSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALE-FYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLE-NLDQFKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKE-IHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMS--RRDV 575          

Query:  286 PSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEM-PERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKI 1761
            P + +A  +   +   + IH  +I  G  S    +  L+  Y+       ++ +F  + P ++V  WN++I  + ++G   +A+E + K+R S  +P+  T  +VI +CA LFD E G  ++++++      D FV +ALVDMY + G L  A++VF+++P++++V+WNS+I+ YS  G     ++ +  +      P   T SS+L A      +  G+ +H F +++ + + + + + L+ +Y      + A+ VF++M   ++VS+N MI GY+K+     ++ ++ +  +   +P+ +TV+S+L AC  L  L   K I+  ++ + F     +   L+D+YAKCG +  A +VFN +  +D VSW S+I+ Y   G  +EA+KLF  M     + D +T L ++S  + +  +  G    +  I + GI   +   + LID+  + G + ++ +I   +S    D    +T+ SAC    +   G+++
Sbjct:    8 PFISRALSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKS-GICIDLSVSNALIDMYAKCGEVGDSLKIF--SSMGTGDTVTWNTVISACVRFGDFATGLQV 496          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL+ G+ +H  +L LG  +D  +C  L++ YF      SA+ +F ++    +++ +N ++ G ++     +A+ELF+ +     + PDS T  S++ AC A G +  G+ +H +  K GF S+  +  +L+ +YAKC   + A+  F E    +V  WN ++  Y      + +  +F +M+     PN  T  +++ +C RL DLE G +IH ++IK    L+++V S L+DMY K G LD A ++  +   K+VV+W +MIA Y+        +  FR+M   G        ++ + AC+    L  G+ IHA    +   +D+   ++L+ LY   G +  +   FE+    + ++WN ++SG+ + G+   AL ++  M   G+  N  T  S + A S+ A +++GK++H  +  + +++   +  AL+ MYAKCG++ +A   F  +  ++ VSW ++I AY  HG   EAL  F +M  SN +P+ VTL+ VLSACSH+GLVD+G  +F  M + YG+ P+ EHY C++D+L RAG L+ A E +Q    I+ D  +  TL SAC +H+N+++G   A  L+E  P+D +TY++LSN YA  KKWD     R KMKE G++K PG SWIE+   IH F+VGD++HP ++
Sbjct:  303 SLEIGEQLHGLVLKLGFSSDTYVCNALVSLYFHLGNLISAEHIFSNMSQRDAVT-YNTLINGLSQCGYGEKAMELFKRM-HLDGLEPDSNTLASLVVACSADGTLFRGQQLHAYTTKLGFASNNKIEGALLNLYAKCADIETALDYFLETEVENVVLWNVMLVAYGLLDDLRNSFRIFRQMQIEEIVPNQYTYPSILKTCIRLGDLELGEQIHSQIIKTNFQLNAYVCSVLIDMYAKLGKLDTAWDILIRFAGKDVVSWTTMIAGYTQYNFDDKALTTFRQMLDRGIRSDEVGLTNAVSACAGLQALKEGQQIHAQACVSGFSSDLPFQNALVTLYSRCGKIEESYLAFEQTEAGDNIAWNALVSGFQQSGNNEEALRVFVRMNREGIDNNNFTFGSAVKAASETANMKQGKQVHAVITKTGYDSETEVCNALISMYAKCGSISDAEKQFLEVSTKNEVSWNAIINAYSKHGFGSEALDSFDQMIHSNVRPNHVTLVGVLSACSHIGLVDKGIAYFESMNSEYGLSPKPEHYVCVVDMLTRAGLLSRAKEFIQE-MPIKPDALVWRTLLSACVVHKNMEIGEFAAHHLLELEPEDSATYVLLSNLYAVSKKWDARDLTRQKMKEKGVKKEPGQSWIEVKNSIHSFYVGDQNHPLAD 955          

Query:   31 IHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEA 1653
            IH ++L  GL++   +C  LI+ Y    F D A+ VF  +      S W  +++G +KN    EA+ LF  +     I P  Y + SVL AC  +  +  G+ +H  ++K GF SD  V ++LV +Y        A  +F  M +RD   +NT+I+   Q G  +KAMELF++M   G  P+S TL +++ +C+    L RG ++H    K     ++ +  AL+++Y KC  ++ A + F +  ++NVV WN M+ AY +  D  +  + FR+M  E   P   T+ SIL  C R   L  G+ IH+ +I+   + + Y+ S LID+Y   G + +A ++  +    + VSW  MI+GY +      AL  +  M + G+R + + +T+ +SAC+ L AL++G++IH     S F ++     AL+ +Y++CG ++E+   F +    D ++W ++++ +   G   EAL++F  M +     +  T  + + A S    + +G    + +IT  G     E  + LI +  + G +++A
Sbjct:  209 IHARILYQGLRDSTVVCNPLIDLYSRNGFVDLARRVFDGLRLKDHSS-WVAMISGLSKNECEAEAIRLFCDMYVLG-IMPTPYAFSSVLSACKKIESLEIGEQLHGLVLKLGFSSDTYVCNALVSLYFHLGNLISAEHIFSNMSQRDAVTYNTLINGLSQCGYGEKAMELFKRMHLDGLEPDSNTLASLVVACSADGTLFRGQQLHAYTTKLGFASNNKIEGALLNLYAKCADIETALDYFLETEVENVVLWNVMLVAYGLLDDLRNSFRIFRQMQIEEIVPNQYTYPSILKTCIRLGDLELGEQIHSQIIKTNFQLNAYVCSVLIDMYAKLGKLDTAWDILIRFAGKDVVSWTTMIAGYTQYNFDDKALTTFRQMLDRGIRSDEVGLTNAVSACAGLQALKEGQQIHAQACVSGFSSDLPFQNALVTLYSRCGKIEESYLAFEQTEAGDNIAWNALVSGFQQSGNNEEALRVFVRMNREGIDNNNFTFGSAVKAASETANMKQGKQ-VHAVITKTGYDSETEVCNALISMYAKCGSISDA 746          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFG--KMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDV---DLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLK 1872
            N SL +G+ +H ++L LGL ++  L + L +FY        A  VF  +    +I  WN ++      ++  E   LF  ++    + P+  T+  VL+AC   G V F   + IH  ++  G     VV + L+ +Y++    D A R+FD +  +D + W  +IS   ++    +A+ LF  M   G  P     ++V+S+C ++  LE G ++H  ++K     D++V +ALV +Y   G L  A+ +F  +  ++ V +N++I   S  G     ++ F+RM+ +G  P   T +S+++ACS    L  G+ +HA+  +    ++  I  +L++LY     + +A + F +    N V WNVM+  Y  + D   +  I+  M+   + PN  T  SIL  C +L  LE G++IH  +I + F+ N  +   L+DMYAK G +D A ++  R   +D VSWT+MI  Y  +    +AL  F +M     + D V L   +SAC+ +  + EG     Q   + G    +   + L+ L  R G++ E+Y   ++T E  +++    L+S    +      L + V++ R  I+ N     + +  ++  A++K+  +V  V  K
Sbjct:   98 NGSLDEGRKLHSQILKLGLDSNGCLSEKLFDFYLFKGDLYGAFKVFDEMPE-RTIFTWNKMIKELASRNLIGEVFGLFVRMVS-ENVTPNEGTFSGVLEACRG-GSVAFDVVEQIHARILYQGLRDSTVVCNPLIDLYSRNGFVDLARRVFDGLRLKDHSSWVAMISGLSKNECEAEAIRLFCDMYVLGIMPTPYAFSSVLSACKKIESLEIGEQLHGLVLKLGFSSDTYVCNALVSLYFHLGNLISAEHIFSNMSQRDAVTYNTLINGLSQCGYGEKAMELFKRMHLDGLEPDSNTLASLVVACSADGTLFRGQQLHAYTTKLGFASNNKIEGALLNLYAKCADIETALDYFLETEVENVVLWNVMLVAYGLLDDLRNSFRIFRQMQIEEIVPNQYTYPSILKTCIRLGDLELGEQIHSQIIKTNFQLNAYVCSVLIDMYAKLGKLDTAWDILIRFAGKDVVSWTTMIAGYTQYNFDDKALTTFRQMLDRGIRSDEVGLTNAVSACAGLQALKEGQQIHAQACVS-GFSSDLPFQNALVTLYSRCGKIEESYLAFEQT-EAGDNIAWNALVSGFQQSGNNEEALRVFVRMNREGIDNNNFTFGSAVKAASETANMKQGKQVHAVITK 720          

Query:  148 IENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPI--KNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIH-RTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            I   SS++ WN  +      +  VE+L LF  + R  +  P+++T+P V KAC  L  VG  +M+H HLIK+ F SD+ V ++ V M+ KCN  D A ++F+ MPERD   WN ++S + Q G   KA  LF +MR +  TP+SVT+ T+I S +    L+    +H   I+  + +   V +  +  YGKCG LD AK VFE I    + VV+WNSM  AYSV G++      +  M RE   P L+TF ++  +C     L  G+ IH+  I    + DI   ++ I +Y  S    SA+ +F+ M     VSW VMISGY + GD   ALA++  M ++G +P+ +T+ S++S C +  +LE GK I  R  I      N ++  AL+DMY+KCG++ EA ++F+  P +  V+WT+MI  Y  +G  LEALKLF +M   + KP+ +T LAVL AC+H G +++G  +F+ M   Y I P ++HYSC++DLLGR G+L EA E++ R    + D  +   L +AC++HRN+ +  + A  L    P   + Y+ ++N YA+   WD   ++R  MK+  ++K PG S I++N K H F VG+  H ++E+
Sbjct:   11 ISGLSSVNAWNLQIREAVNRNDPVESLLLFREMKRGGF-EPNNFTFPFVAKACARLADVGCCEMVHAHLIKSPFWSDVFVGTATVDMFVKCNSVDYAAKVFERMPERDATTWNAMLSGFCQSGHTDKAFSLFREMRLNEITPDSVTVMTLIQSASFEKSLKLLEAMHAVGIRLGVDVQVTVANTWISTYGKCGDLDSAKLVFEAIDRGDRTVVSWNSMFKAYSVFGEAFDAFGLYCLMLREEFKPDLSTFINLAASCQNPETLTQGRLIHSHAIHLGTDQDIEAINTFISMYSKSEDTCSARLLFDIMTSRTCVSWTVMISGYAEKGDMDEALALFHAMIKSGEKPDLVTLLSLISGCGKFGSLETGKWIDARADIYGCKRDNVMICNALIDMYSKCGSIHEARDIFDNTPEKTVVTWTTMIAGYALNGIFLEALKLFSKMIDLDYKPNHITFLAVLQACAHSGSLEKGWEYFHIMKQVYNISPGLDHYSCMVDLLGRKGKLEEALELI-RNMSAKPDAGIWGALLNACKIHRNVKIAEQAAESLFNLEPQMAAPYVEMANIYAAAGMWDGFARIRSIMKQRNIKKYPGESVIQVNGKNHSFTVGEHGHVENEV 622          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIE-NPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDS-FVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHG-KFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKM-PKTNTVSWNVMIS 1104
            SLK  + +H   + LG+     +    I+ Y  C   DSAKLVF++I+    ++  WN +   ++      +A  L+  +LR  +  PD  T+ ++  +C     +  G++IH+H I  G   DI   ++ + MY+K      A  LFD M  R    W  +IS Y + G   +A+ LF  M  SG  P+ VTL ++IS C +   LE G  I           D+  + +AL+DMY KCG +  A+++F+  P K VV W +MIA Y++ G  +  ++ F +M      P   TF ++L AC+ S  L  G ++ H       I   +  YS ++DL    G +  A  +   M  K +   W  +++
Sbjct:  168 SLKLLEAMHAVGIRLGVDVQVTVANTWISTYGKCGDLDSAKLVFEAIDRGDRTVVSWNSMFKAYSVFGEAFDAFGLYCLMLREEF-KPDLSTFINLAASCQNPETLTQGRLIHSHAIHLGTDQDIEAINTFISMYSKSEDTCSARLLFDIMTSRTCVSWTVMISGYAEKGDMDEALALFHAMIKSGEKPDLVTLLSLISGCGKFGSLETGKWIDARADIYGCKRDNVMICNALIDMYSKCGSIHEARDIFDNTPEKTVVTWTTMIAGYALNGIFLEALKLFSKMIDLDYKPNHITFLAVLQACAHSGSLEKGWEYFHIMKQVYNISPGLDHYSCMVDLLGRKGKLEEALELIRNMSAKPDAGIWGALLN 535          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIEN--PSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTG-FVSDIVVASSLVCMYAKC-NVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKC---GCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGD-SISCIQFFRRMNREG-TSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            GKL+H +++   ++ D  L  +LI+ Y        A+ VF+++       +  W+ +M  +  N   ++A+++F   L    + P+ Y Y +V++AC     VG G++    L+KTG F SD+ V  SL+ M+ K  N F+ A ++FD+M E +V  W  +I+   Q G  ++A+  F  M  SGF  +  TL++V S+CA L +L  G ++H   I+  LV D  V  +LVDMY KC   G +D  ++VF+++   +V++W ++I  Y    + +   I  F  M  +G   P   TFSS   AC   +    GK +     +  + ++  + +S+I ++  S  +  A+  FE + + N VS+N  + G  +  ++  A  +  ++ E  +  +A T  S+LS  + + ++ KG++IH  V+      N+ +  AL+ MY+KCG++D A  VFN + NR+ +SWTSMIT +  HG A+  L+ F +M +   KP+ VT +A+LSACSHVGLV EG   FN M  ++ IKP++EHY+C++DLL RAG L +A+E +  T   + DV +  T   ACR+H N +LG   AR ++E +P++ + YI LSN YA   KW+E  ++R KMKE  L K  GCSWIE+  KIH F+VGD +HP +
Sbjct:   81 GKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLV-PNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDD--VECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVVKLGLSCNQPVCNALISMYSKCGSIDTASRVFNFMENRNVISWTSMITGFAKHGFAIRVLETFNQMIEEGVKPNEVTYVAILSACSHVGLVSEGWRHFNSMYEDHKIKPKMEHYACMVDLLCRAGLLTDAFEFI-NTMPFQADVLVWRTFLGACRVHSNTELGKLAARKILELDPNEPAAYIQLSNIYACAGKWEESTEMRRKMKERNLVKEGGCSWIEVGDKIHKFYVGDTAHPNA 736          

Query:  514 GQAQKAMELFEKMRNSGFTP-NSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFE---QIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIR-NIIEADIYIYSSLIDLYFVSG--SVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKC---GAVDEALNVFNRLPNRDPVSWTSMITAYGSH-GQALEALKLFGEM-QQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHS-TYIMLSNTYASVKKWDEVKKVRLKMKELGLRKN-PGCS 1911
            G  + A+   + M   G  P +SVT ++++ SC R  D   G  +H  LI+  +  DS + ++L+ +Y K G    A++VFE   +   ++VV+W++M+A Y   G  +  I+ F      G  P    +++++ ACS S  +  G+    F+++    E+D+ +  SLID+ FV G  S  +A  VF+KM + N V+W +MI+  +++G    A+  + DM  +G   +  T++S+ SAC++L  L  GK++H   I S    +  +  +L+DMYAKC   G+VD+   VF+R+ +   +SWT++IT Y  +   A EA+ LF EM  Q + +P+  T  +   AC ++     G     Q     G+       + +I +  ++ R+ +A    +  SE +  V   + L   CR + N +   K+   + E+     + T+  L +  A+V    + +++  ++ +LGL  N P C+
Sbjct:   40 GDLRGAVSALDLMARDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDM-FVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDD--VECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKR-GLASNSSVANSVISMFVKSDRMEDAQRAFESLSE-KNLVSYNTFLDGTCR-NLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVVKLGLSCNQPVCN 513          

Query:  271 DSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEM---PERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIK-DQLVLDSFVTSALVDMYGKC-GCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLY---FVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDY-FGALAIYDDMKEAG-VRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEI 1662
            DS T+ S+LK+C        GK++H  LI+     D V+ +SL+ +Y+K      A  +F+ M    +RDV  W+ +++CY  +G+   A+++F +    G  PN    T VI +C+    +  G      L+K      D  V  +L+DM+ K     + A +VF+++   NVV W  MI      G     I+FF  M   G      T SS+  AC+    L  GK +H++ IR+ +  D  +  SL+D+Y      GSV   + VF++M   + +SW  +I+GY+K  +    A+ ++ +M   G V PN  T +S   AC  L+    GK++          +N  +  +++ M+ K   +++A   F  L  ++ VS+ + +     +    +A KL  E+ +        T  ++LS  ++VG + +G    +Q++   G+       + LI +  + G ++ A  +
Sbjct:   61 DSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDD--VECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVV-KLGLSCNQPVCNALISMYSKCGSIDTASRV 531          

Query:  793 MIAAYSVTGDSISCIQFFRRMNREGTSPT-LTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKM---PKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGK-EIHRTVIDSEFETNEIMMGALLDMYAKC-GAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRA---GRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDH 1797
            +I  +   GD    +     M R+G  P    TFSS+L +C R+     GK +HA +I   IE D  +Y+SLI LY  SG  + A++VFE M    K + VSW+ M++ Y   G    A+ ++ +  E G+ PN    T+++ ACS    +  G+  +   +    FE++  +  +L+DM+ K   + + A  VF+++   + V+WT MIT     G   EA++ F +M  S  + D  TL +V SAC+ +  +  G    +  I + G+   +E    L+D+  +    G +++  ++  R     ED  ++S         +N +L  +   L  E     H
Sbjct:   32 LILRHLNAGDLRGAVSALDLMARDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRS-GLVDDVE--CSLVDMYAKCSADGSVDDCRKVFDR----MEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGH 368          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVG-----FGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMP-ERDVACWNTVI 495
            S+++G+ IH +++ LGL  +  +C  LI+ Y  C   D+A  VF  +EN + IS W  ++TGF K+   +  LE F  ++    + P+  TY ++L AC  +G V      F  M  +H IK      +   + +V +  +  +   A    + MP + DV  W T +
Sbjct:  489 SIRKGEQIHSQVVKLGLSCNQPVCNALISMYSKCGSIDTASRVFNFMENRNVIS-WTSMITGFAKHGFAIRVLETFNQMIE-EGVKPNEVTYVAILSACSHVGLVSEGWRHFNSMYEDHKIK----PKMEHYACMVDLLCRAGLLTDAFEFINTMPFQADVLVWRTFL 650          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIG---PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSG--FTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDK 1959
            G  +H  ++  GL  D  +   L++FY +  F   A  +F  +   + +S WN ++  F+ N    E+  L   ++     G   PD  T  +VL  C    ++G GK +H   +K     ++V+ ++L+ MY+KC     A  +F     ++V  WNT++  +  +G      ++  +M   G     + VT+   +  C     L    ++H   +K + V +  V +A V  Y KCG L  A+ VF  I  K V +WN++I  ++ + D    +    +M   G  P   T  S+L ACS+   L  GK +H F+IRN +E D+++Y S++ LY   G + + + +F+ M   + VSWN +I+GY++ G    AL ++  M   G++   I++  +  ACS L +L  G+E H   +    E +  +  +L+DMYAK G++ ++  VFN L  +   SW +MI  YG HG A EA+KLF EMQ++   PD +T L VL+AC+H GL+ EG  + +QM +++G+KP ++HY+C+ID+LGRAG+L++A  ++        DV +  +L S+CR+H+NL++G K+A  L E  P+    Y++LSN YA + KW++V+KVR +M E+ LRK+ GCSWIE+N+K+  F VG++
Sbjct:  206 GLAVHGLVVKTGLVEDVFVGNALVSFYGTHGFVTDALQLFDIMPERNLVS-WNSMIRVFSDNGFSEESFLLLGEMMEENGDGAFMPDVATLVTVLPVCAREREIGLGKGVHGWAVKLRLDKELVLNNALMDMYSKCGCITNAQMIFKMNNNKNVVSWNTMVGGFSAEGDTHGTFDVLRQMLAGGEDVKADEVTILNAVPVCFHESFLPSLKELHCYSLKQEFVYNELVANAFVASYAKCGSLSYAQRVFHGIRSKTVNSWNALIGGHAQSNDPRLSLDAHLQMKISGLLPDSFTVCSLLSACSKLKSLRLGKEVHGFIIRNWLERDLFVYLSVLSLYIHCGELCTVQALFDAMEDKSLVSWNTVITGYLQNGFPDRALGVFRQMVLYGIQLCGISMMPVFGACSLLPSLRLGREAHAYALKHLLEDDAFIACSLIDMYAKNGSITQSSKVFNGLKEKSTASWNAMIMGYGIHGLAKEAIKLFEEMQRTGHNPDDLTFLGVLTACNHSGLIHEGLRYLDQMKSSFGLKPNLKHYACVIDMLGRAGQLDKALRVVAEEMSEEADVGIWKSLLSSCRIHQNLEMGEKVAAKLFELEPEKPENYVLLSNLYAGLGKWEDVRKVRQRMNEMSLRKDAGCSWIELNRKVFSFVVGER 855          

Query:   13 LKQGKLIHQKML-TLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAM----ELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRM--NREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIE---HYSC-LIDLLGRAGRLNEAYEILQRTSE 1680
            ++ G+ IHQ +  +  L+ND  LC  +I  Y  C   D ++ VF ++ +  ++  WN V++ +++N ++ E LE F  ++    + PD +TYP V+KAC  +  VG G  +H  ++KTG V D+ V ++LV  Y        A++LFD MPER++  WN++I  +  +G ++++     E+ E+  +  F P+  TL TV+  CAR  ++  G  +H   +K +L  +  + +AL+DMY KCGC+  A+ +F+    KNVV+WN+M+  +S  GD+       R+M    E       T  + +  C   + L   K +H + ++     +  + ++ +  Y   GS+S A+ VF  +      SWN +I G+ +  D   +L  +  MK +G+ P++ TV S+LSACS+L +L  GKE+H  +I +  E +  +  ++L +Y  CG +     +F+ + ++  VSW ++IT Y  +G    AL +F +M     +  G++++ V  ACS +  +  G     +    Y +K  +E     +C LID+  + G + ++ ++     E
Sbjct:  100 IEMGRKIHQLVSGSTRLRNDDVLCTRIITMYAMCGSPDDSRFVFDALRS-KNLFQWNAVISSYSRNELYDEVLETFIEMISTTDLLPDHFTYPCVIKACAGMSDVGIGLAVHGLVVKTGLVEDVFVGNALVSFYGTHGFVTDALQLFDIMPERNLVSWNSMIRVFSDNGFSEESFLLLGEMMEENGDGAFMPDVATLVTVLPVCAREREIGLGKGVHGWAVKLRLDKELVLNNALMDMYSKCGCITNAQMIFKMNNNKNVVSWNTMVGGFSAEGDTHGTFDVLRQMLAGGEDVKADEVTILNAVPVCFHESFLPSLKELHCYSLKQEFVYNELVANAFVASYAKCGSLSYAQRVFHGIRSKTVNSWNALIGGHAQSNDPRLSLDAHLQMKISGLLPDSFTVCSLLSACSKLKSLRLGKEVHGFIIRNWLERDLFVYLSVLSLYIHCGELCTVQALFDAMEDKSLVSWNTVITGYLQNGFPDRALGVFRQMVLYGIQLCGISMMPVFGACSLLPSLRLG-----REAHAYALKHLLEDDAFIACSLIDMYAKNGSITQSSKVFNGLKE 660          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKN-LINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQ---VGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD-QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNRE-GTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKE-----------AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            ++ GK IH  +   G   D     N L+N Y  C    +   VF  I   + +S WN +++       +  ALE F  +L    + P S+T  SV+ AC  L     +  GK +H + ++ G ++  ++ ++LV MY K      +  L      RD+  WNTV+S   Q+ Q  +A+E   +M   G  P+  T+++V+ +C+ L  L  G ++H   +K+  L  +SFV SALVDMY  C  +   + VF+ +  + +  WN+MIA YS        +  F  M    G     TT + ++ AC RS      + IH F+++  ++ D ++ ++L+D+Y   G +  A  +F KM   + V+WN MI+GYV    +  AL +   M+              ++PN+IT+ +IL +C+ L+AL KGKEIH   I +   T+  +  AL+DMYAKCG +  +  VF+++P ++ ++W  +I AYG HG   EA+ L   M     KP+ VT ++V +ACSH G+VDEG   F  M  +YG++P  +HY+C++DLLGRAGR+ EAY+++             S+L  A R+H NL++G   A+ LI+  P+  S Y++L+N Y+S   WD+  +VR  MKE G+RK PGCSWIE   ++H F  GD SHPQSE
Sbjct:  113 MELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVS-WNSLISSLCSFEKWEMALEAFRCMLD-ENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNSFII-NTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSE 781          

Query:  148 IENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGF-VSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQL---VLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRN-IIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKE-AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQ-----------QSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLI 1776
            I    S   W  ++    ++++  EA+  +  ++    I PD+Y +P++LKA   L  +  GK IH H+ K G+ V  + VA++LV +Y KC  F    ++FD + ER+   WN++IS      + + A+E F  M +    P+S TL +V+++C+ L  +  G+ + K++    L    L+SF+ + LV MYGK G L  +K +      +++V WN+++++       +  +++ R M  EG  P   T SS+L ACS    L  GK +HA+ ++N  ++ + ++ S+L+D+Y     V S + VF+ M       WN MI+GY +      AL ++  M+E AG+  N+ T+  ++ AC +  A  + + IH  V+    + +  +   L+DMY++ G +D A+ +F ++ +RD V+W +MIT Y       +AL L  +MQ           + + KP+ +TL+ +L +C+ +  + +G       I N  +   +   S L+D+  + G L  + ++  +  +  ++V   + +  A  +H N    + + R+++
Sbjct:   56 ISQSRSPEWWIDLLRSKVRSNLLREAVLTYVDMIVLG-IKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNL-PMPEGLMMGKQVHAYGLRKGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKN-NLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQ--KNVITWNVIIMAYGMHGNGQEAIDLLRMMM 610          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL++ KL+HQ++LTLGL+ D  LCK+LIN YF+C    SA+ VF++ +  S + +WN +M+G++KN MF + LE+F+ LL      PDS+T+P+V+KA GALG+   G+MIH  ++K+G+V D+VVASSLV MYAK N+F+ ++++FDEMPERDVA WNTVISC+YQ G+A+KA+ELF +M +SGF PNSV+LT  IS+C+RL  LERG +IH++ +K    LD +V SALVDMYGKC CL++A+EVF+++P K++VAWNSMI  Y   GDS SC++   RM  EGT P+ TT +SIL+ACSRS  LLHGKFIH ++IR+++ ADIY+  SLIDLYF  G  + A+ VF K  K    SWNVMIS Y+ VG++F A+ +YD M   GV+P+ +T TS+L ACSQLAALEKGK+IH ++ +S  ET+E+++ ALLDMY+KCG   EA  +FN +P +D VSWT MI+AYGSHGQ  EAL  F EMQ+   KPDGVTLLAVLSAC H GL+DEG  FF+QM + YGI+P IEHYSC+ID+LGRAGRL EAYEI+Q+T E  ++ +LLSTLFSAC LH    LG +IARLL+E  PDD STY++L N YAS + WD  ++VRLKMKE+GLRK PGCSWIE++ K+  FF  D+SH ++E
Sbjct:   19 SLRRIKLVHQRILTLGLRRDVVLCKSLINVYFTCKDHCSARHVFENFDIRSDVYIWNSLMSGYSKNSMFHDTLEVFKRLLNCSICVPDSFTFPNVIKAYGALGREFLGRMIHTLVVKSGYVCDVVVASSLVGMYAKFNLFENSLQVFDEMPERDVASWNTVISCFYQSGEAEKALELFGRMESSGFEPNSVSLTVAISACSRLLWLERGKEIHRKCVKKGFELDEYVNSALVDMYGKCDCLEVAREVFQKMPRKSLVAWNSMIKGYVAKGDSKSCVEILNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFIHGYVIRSVVNADIYVNCSLIDLYFKCGEANLAETVFSKTQKDVAESWNVMISSYISVGNWFKAVEVYDQMVSVGVKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQMRSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTPETSDNAELLSTLFSACCLHLEHSLGDRIARLLVENYPDDASTYMVLFNLYASGESWDAARRVRLKMKEMGLRKKPGCSWIEMSDKVCHFFAEDRSHLRAE 674          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVT--SALVDMYGKCGCLDMAKEVFEQIP 765
            + +L  GK IH  ++   +  D  +  +LI+ YF C   + A+ VF   +   + S WN +++ +     + +A+E+++ ++    + PD  T+ SVL AC  L  +  GK IH  + ++   +D ++ S+L+ MY+KC     A R+F+ +P++DV  W  +IS Y   GQ ++A+  F++M+  G  P+ VTL  V+S+C     ++ G+K   ++ + +  ++  +   S ++D+ G+ G L  A E+ +Q P
Sbjct:  322 SRNLLHGKFIHGYVIRSVVNADIYVNCSLIDLYFKCGEANLAETVFSKTQKDVAES-WNVMISSYISVGNWFKAVEVYDQMVSVG-VKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQM-RSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTP 574          

Query:    7 NSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            +SLK+ + I   +   GL  +      L++ +      D A  VF+ I++  ++ L++ ++ GF K     +AL+ F  + RY  + P  Y +  +LK CG   ++  GK IH  L+K+GF  D+   + L  MYAKC   + A ++FD MPERD+  WNT+++ Y Q+G A+ A+E+ + M      P+ +T+ +V+ + + L  +  G +IH   ++        +++ALVDMY KCG L+ A+++F+ +  +NVV+WNSMI AY    +    +  F++M  EG  PT  +    L AC+    L  G+FIH   +   ++ ++ + +SLI +Y     V +A ++F K+     VSWN MI G+ + G    AL  +  M+   V+P+  T  S+++A ++L+     K IH  V+ S  + N  +  AL+DMYAKCGA+  A  +F+ +  R   +W +MI  YG+HG    AL+LF EMQ+   KP+GVT L+V+SACSH GLV+ G   F  M  NY I+  ++HY  ++DLLGRAGRLNEA++ + +   ++  V++   +  AC++H+N++   K A  L E NPDD   +++L+N Y +   W++V +VR+ M   GLRK PGCS +EI  ++H FF G  +HP S+
Sbjct:   48 SSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNV-LYHTMLKGFAKVSDLDKALQFFVRM-RYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRSGFDSLVNISTALVDMYAKCGSLETARQLFDGMLERNVVSWNSMIDAYVQNENPKEAMLIFQKMLDEGVKPTDVSVMGALHACADLGDLERGRFIHKLSVELGLDRNVSVVNSLISMYCKCKEVDTAASMFGKLQSRTLVSWNAMILGFAQNGRPIDALNYFSQMRSRTVKPDTFTYVSVITAIAELSITHHAKWIHGVVMRSCLDKNVFVTTALVDMYAKCGAIMIARLIFDMMSERHVTTWNAMIDGYGTHGFGKAALELFEEMQKGTIKPNGVTFLSVISACSHSGLVEAGLKCFYMMKENYSIELSMDHYGAMVDLLGRAGRLNEAWDFIMQ-MPVKPAVNVYGAMLGACQIHKNVNFAEKAAERLFELNPDDGGYHVLLANIYRAASMWEKVGQVRVSMLRQGLRKTPGCSMVEIKNEVHSFFSGSTAHPDSK 701          

Query:  904 LACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEI 1662
            L   R + L   + I   + +N +  + +  + L+ L+   GSV  A  VFE +     V ++ M+ G+ KV D   AL  +  M+   V P     T +L  C   A L  GKEIH  ++ S F  +   M  L +MYAKC  V+EA  VF+R+P RD VSW +++  Y  +G A  AL++   M + N KP  +T+++VL A S + L+  G       + + G    +   + L+D+  + G L  A ++
Sbjct:   42 LLLERCSSLKELRQILPLVFKNGLYQEHFFQTKLVSLFCRYGSVDEAARVFEPIDSKLNVLYHTMLKGFAKVSDLDKALQFFVRMRYDDVEPVVYNFTYLLKVCGDEAELRVGKEIHGLLVKSGFSLDLFAMTGLENMYAKCRQVNEARKVFDRMPERDLVSWNTIVAGYSQNGMARMALEMVKSMCEENLKPSFITIVSVLPAVSALRLISVGKEIHGYAMRS-GFDSLVNISTALVDMYAKCGSLETARQL 293          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSA-KLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNS-GFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNRE-----------------------------------GTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEA-------DIYIYSSLIDLYFVSGSVSSAKNVFEKM-PKT-NTVSWNVMISGYVKVGDYFGALAIYDDM--KEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMG-ALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            ++ Q KLIHQK+L+ G+     L  +LI+ Y S      A  L+ +   + + +  WN ++  +  N    + L LF  L+      PD+YT+P V KACG +  V  G+  H   + TGF+S++ V ++LV MY++C     A ++FDEM   DV  WN++I  Y + G+ + A+E+F +M N  G  P+++TL  V+  CA L     G ++H   +  +++ + FV + LVDMY KCG +D A  VF  + +K+VV+WN+M+A YS  G     ++ F +M  E                                   G  P   T  S+L  C+    L+HGK IH + I+  I+        +  + + LID+Y     V +A+ +F+ + PK  + V+W VMI GY + GD   AL +  +M  ++   RPNA T++  L AC+ LAAL  GK+IH   + ++     + +   L+DMYAKCG++ +A  VF+ +  ++ V+WTS++T YG HG   EAL +F EM++   K DGVTLL VL ACSH G++D+G  +FN+M T +G+ P  EHY+CL+DLLGRAGRLN A  +++        V  ++ L S CR+H  ++LG   A  + E   +   +Y +LSN YA+  +W +V ++R  M+  G++K PGCSW+E  K    FFVGDK+HP ++
Sbjct:   40 TISQVKLIHQKLLSFGILT-LNLTSHLISTYISVGCLSHAVSLLRRFPPSDAGVYHWNSLIRSYGDNGCANKCLYLF-GLMHSLSWTPDNYTFPFVFKACGEISSVRCGESAHALSLVTGFISNVFVGNALVAMYSRCRSLSDARKVFDEMSVWDVVSWNSIIESYAKLGKPKVALEMFSRMTNEFGCRPDNITLVNVLPPCASLGTHSLGKQLHCFAVTSEMIQNMFVGNCLVDMYAKCGMMDEANTVFSNMSVKDVVSWNAMVAGYSQIGRFEDAVRLFEKMQEEKIKMDVVTWSAAISGYAQRGLGYEALGVCRQMLSSGIKPNEVTLISVLSGCASVGALMHGKEIHCYAIKYPIDLRKNGHGDENMVINQLIDMYAKCKKVDTARAMFDSLSPKERDVVTWTVMIGGYSQHGDANKALELLSEMFEEDCQTRPNAFTISCALVACASLAALRIGKQIHAYALRNQQNAVPLFVSNCLIDMYAKCGSISDARLVFDNMMAKNEVTWTSLMTGYGMHGYGEEALGIFDEMRRIGFKLDGVTLLVVLYACSHSGMIDQGMEYFNRMKTVFGVSPGPEHYACLVDLLGRAGRLNAALRLIEEMPMEPPPVVWVAFL-SCCRIHGKVELGEYAAEKITELASNHDGSYTLLSNLYANAGRWKDVTRIRSLMRHKGVKKRPGCSWVEGIKGTTTFFVGDKTHPHAK 741          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDM-KEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            + SLK GK +   +   G   D  L   L   Y +C     A  VF  ++   ++  WN +M    K+  F  ++ LF+ ++    +  DSYT+  V K+  +L  V  G+ +H  ++K+GF     V +SLV  Y K    D A ++FDEM ERDV  WN++I+ Y  +G A+K + +F +M  SG   +  T+ +V + CA    +  G  +H   +K     +    + L+DMY KCG LD AK VF ++  ++VV++ SMIA Y+  G +   ++ F  M  EG SP + T +++L  C+R   L  GK +H ++  N +  DI++ ++L+D+Y   GS+  A+ VF +M   + +SWN +I GY K      AL++++ + +E    P+  TV  +L AC+ L+A +KG+EIH  ++ + + ++  +  +L+DMYAKCGA+  A  +F+ + ++D VSWT MI  YG HG   EA+ LF +M+Q+  + D ++ +++L ACSH GLVDEG  FFN M     I+P +EHY+C++D+L R G L +AY  ++    I  D  +   L   CR+H ++ L  K+A  + E  P++   Y++++N YA  +KW++VK++R ++ + GLRKNPGCSWIEI  +++ F  GD S+P++E
Sbjct:  107 SKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKAL-FWNILMNELAKSGDFSGSIGLFKKMMSSG-VEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDRHVANSLVDMYAKCGALLLAHMLFDDIASKDLVSWTVMIAGYGMHGFGKEAIALFNQMRQAGIEADEISFVSLLYACSHSGLVDEGWRFFNIMRHECKIEPTVEHYACIVDMLARTGDLIKAYRFIE-NMPIPPDATIWGALLCGCRIHHDVKLAEKVAEKVFELEPENTGYYVLMANIYAEAEKWEQVKRLRKRIGQRGLRKNPGCSWIEIKGRVNIFVAGDSSNPETE 762          

Query:  271 DSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFG-EMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRL 1644
            D  T  SVL+ C     +  GK + N +   GFV D  + S L  MY  C     A R+FDE+       WN +++   + G    ++ LF+KM +SG   +S T + V  S + L  +  G ++H  ++K      + V ++LV  Y K   +D A++VF+++  ++V++WNS+I  Y   G +   +  F +M   G    L T  S+   C+ S  +  G+ +H+  ++     +    ++L+D+Y   G + SAK VF +M   + VS+  MI+GY + G    A+ ++++M+E G+ P+  TVT++L+ C++   L++GK +H  + +++   +  +  AL+DMYAKCG++ EA  VF+ +  +D +SW ++I  Y  +  A EAL LF   +++    PD  T+  VL AC+ +   D+G      ++ N     R    + L+D+  + G L
Sbjct:   93 DPRTLCSVLQLCADSKSLKDGKEVDNFIRGNGFVIDSNLGSKLSLMYTNCGDLKEASRVFDEVKIEKALFWNILMNELAKSGDFSGSIGLFKKMMSSGVEMDSYTFSCVSKSFSSLRSVHGGEQLHGFILKSGFGERNSVGNSLVAFYLKNQRVDSARKVFDEMTERDVISWNSIINGYVSNGLAEKGLSVFVQMLVSGIEIDLATIVSVFAGCADSRLISLGRAVHSIGVKACFSREDRFCNTLLDMYSKCGDLDSAKAVFREMSDRSVVSYTSMIAGYAREGLAGEAVKLFEEMEEEGISPDVYTVTAVLNCCARYRLLDEGKRVHEWIKENDLGFDIFVSNALMDMYAKCGSMQEAELVFSEMRVKDIISWNTIIGGYSKNCYANEALSLFNLLLEEKRFSPDERTVACVLPACASLSAFDKGREIHGYIMRNGYFSDR-HVANSLVDMYAKCGAL 550          

Query:   16 KQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            + G L+++++L +G ++D  +   L++ Y        A+ VF  +     +S WN +++G++ +  + EALE++  L +  +I PDS+T  SVL A G L  V  G+ +H   +K+G  S +VV + LV MY K      A R+FDEM  RD   +NT+I  Y +    ++++ +F +  +  F P+ +T+++V+ +C  L DL     I+  ++K   VL+S V + L+D+Y KCG +  A++VF  +  K+ V+WNS+I+ Y  +GD +  ++ F+ M          T+  ++   +R A L  GK +H+  I++ I  D+ + ++LID+Y   G V  +  +F  M   +TV+WN +IS  V+ GD+   L +   M+++ V P+  T    L  C+ LAA   GKEIH  ++   +E+   +  AL++MY+KCG ++ +  VF R+  RD V+WT MI AYG +G+  +AL+ F +M++S   PD V  +A++ ACSH GLVDEG   F +M T+Y I P IEHY+C++DLL R+ ++++A E +Q    I+ D  + +++  ACR   +++   +++R +IE NPDD    I+ SN YA+++KWD+V  +R  +K+  + KNPG SWIE+ K +H F  GD S PQSE
Sbjct:  123 EMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVS-WNSLISGYSSHGYYEEALEIYHEL-KNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKEIHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMSRRDVVTWTGMIYAYGMYGEGEKALETFADMEKSGIVPDSVVFIAIIYACSHSGLVDEGLACFEKMKTHYKIDPMIEHYACVVDLLSRSQKISKAEEFIQ-AMPIKPDASIWASVLRACRTSGDMETAERVSRRIIELNPDDPGYSILASNAYAALRKWDKVSLIRKSLKDKHITKNPGYSWIEVGKNVHVFSSGDDSAPQSE 772          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDV 1695
            +++L + + IH  +++LGL +       LI+ Y       S+  VF+ +    ++ LWN ++  F+KN +F EALE F   LR   + PD YT+PSV+KAC  L     G +++  ++  GF SD+ V ++LV MY++  +   A ++FDEMP RD+  WN++IS Y   G  ++A+E++ +++NS   P+S T+++V+ +   L  +++G  +H   +K  +     V + LV MY K      A+ VF+++ +++ V++N+MI  Y         ++ F   N +   P L T SS+L AC     L   K+I+ +M++     +  + + LID+Y   G + +A++VF  M   +TVSWN +ISGY++ GD   A+ ++  M     + + IT   ++S  ++LA L+ GK +H   I S    +  +  AL+DMYAKCG V ++L +F+ +   D V+W ++I+A    G     L++  +M++S   PD  T L  L  C+ +     G    +  +  +G +  ++  + LI++  + G L  +  + +R S  R DV
Sbjct:   17 SSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALE-FYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLE-NLDQFKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKSGICIDLSVSNALIDMYAKCGEVGDSLKIFSSMGTGDTVTWNTVISACVRFGDFATGLQVTTQMRKSEVVPDMATFLVTLPMCASLAAKRLGKE-IHCCLLRFGYESELQIGNALIEMYSKCGCLENSSRVFERMS--RRDV 575          

Query:  286 PSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEM-PERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKI 1761
            P + +A  +   +   + IH  +I  G  S    +  L+  Y+       ++ +F  + P ++V  WN++I  + ++G   +A+E + K+R S  +P+  T  +VI +CA LFD E G  ++++++      D FV +ALVDMY + G L  A++VF+++P++++V+WNS+I+ YS  G     ++ +  +      P   T SS+L A      +  G+ +H F +++ + + + + + L+ +Y      + A+ VF++M   ++VS+N MI GY+K+     ++ ++ +  +   +P+ +TV+S+L AC  L  L   K I+  ++ + F     +   L+D+YAKCG +  A +VFN +  +D VSW S+I+ Y   G  +EA+KLF  M     + D +T L ++S  + +  +  G    +  I + GI   +   + LID+  + G + ++ +I   +S    D    +T+ SAC    +   G+++
Sbjct:    8 PFISRALSSSSNLNELRRIHALVISLGLDSSDFFSGKLIDKYSHFREPASSLSVFRRVSPAKNVYLWNSIIRAFSKNGLFPEALEFYGKLRESKVSPDKYTFPSVIKACAGLFDAEMGDLVYEQILDMGFESDLFVGNALVDMYSRMGLLTRARQVFDEMPVRDLVSWNSLISGYSSHGYYEEALEIYHELKNSWIVPDSFTVSSVLPAFGNLLVVKQGQGLHGFALKSGVNSVVVVNNGLVAMYLKFRRPTDARRVFDEMDVRDSVSYNTMICGYLKLEMVEESVRMFLENLDQ-FKPDLLTVSSVLRACGHLRDLSLAKYIYNYMLKAGFVLESTVRNILIDVYAKCGDMITARDVFNSMECKDTVSWNSIISGYIQSGDLMEAMKLFKMMMIMEEQADHITYLMLISVSTRLADLKFGKGLHSNGIKS-GICIDLSVSNALIDMYAKCGEVGDSLKIF--SSMGTGDTVTWNTVISACVRFGDFATGLQV 496          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL+ G+ +H  +L LG  +D  +C  L++ YF      SA+ +F ++    +++ +N ++ G ++     +A+ELF+ +     + PDS T  S++ AC A G +  G+ +H +  K GF S+  +  +L+ +YAKC   + A+  F E    +V  WN ++  Y      + +  +F +M+     PN  T  +++ +C RL DLE G +IH ++IK    L+++V S L+DMY K G LD A ++  +   K+VV+W +MIA Y+        +  FR+M   G        ++ + AC+    L  G+ IHA    +   +D+   ++L+ LY   G +  +   FE+    + ++WN ++SG+ + G+   AL ++  M   G+  N  T  S + A S+ A +++GK++H  +  + +++   +  AL+ MYAKCG++ +A   F  +  ++ VSW ++I AY  HG   EAL  F +M  SN +P+ VTL+ VLSACSH+GLVD+G  +F  M + YG+ P+ EHY C++D+L RAG L+ A E +Q    I+ D  +  TL SAC +H+N+++G   A  L+E  P+D +TY++LSN YA  KKWD     R KMKE G++K PG SWIE+   IH F+VGD++HP ++
Sbjct:  303 SLEIGEQLHGLVLKLGFSSDTYVCNALVSLYFHLGNLISAEHIFSNMSQRDAVT-YNTLINGLSQCGYGEKAMELFKRM-HLDGLEPDSNTLASLVVACSADGTLFRGQQLHAYTTKLGFASNNKIEGALLNLYAKCADIETALDYFLETEVENVVLWNVMLVAYGLLDDLRNSFRIFRQMQIEEIVPNQYTYPSILKTCIRLGDLELGEQIHSQIIKTNFQLNAYVCSVLIDMYAKLGKLDTAWDILIRFAGKDVVSWTTMIAGYTQYNFDDKALTTFRQMLDRGIRSDEVGLTNAVSACAGLQALKEGQQIHAQACVSGFSSDLPFQNALVTLYSRCGKIEESYLAFEQTEAGDNIAWNALVSGFQQSGNNEEALRVFVRMNREGIDNNNFTFGSAVKAASETANMKQGKQVHAVITKTGYDSETEVCNALISMYAKCGSISDAEKQFLEVSTKNEVSWNAIINAYSKHGFGSEALDSFDQMIHSNVRPNHVTLVGVLSACSHIGLVDKGIAYFESMNSEYGLSPKPEHYVCVVDMLTRAGLLSRAKEFIQE-MPIKPDALVWRTLLSACVVHKNMEIGEFAAHHLLELEPEDSATYVLLSNLYAVSKKWDARDLTRQKMKEKGVKKEPGQSWIEVKNSIHSFYVGDQNHPLAD 955          

Query:   31 IHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEA 1653
            IH ++L  GL++   +C  LI+ Y    F D A+ VF  +      S W  +++G +KN    EA+ LF  +     I P  Y + SVL AC  +  +  G+ +H  ++K GF SD  V ++LV +Y        A  +F  M +RD   +NT+I+   Q G  +KAMELF++M   G  P+S TL +++ +C+    L RG ++H    K     ++ +  AL+++Y KC  ++ A + F +  ++NVV WN M+ AY +  D  +  + FR+M  E   P   T+ SIL  C R   L  G+ IH+ +I+   + + Y+ S LID+Y   G + +A ++  +    + VSW  MI+GY +      AL  +  M + G+R + + +T+ +SAC+ L AL++G++IH     S F ++     AL+ +Y++CG ++E+   F +    D ++W ++++ +   G   EAL++F  M +     +  T  + + A S    + +G    + +IT  G     E  + LI +  + G +++A
Sbjct:  209 IHARILYQGLRDSTVVCNPLIDLYSRNGFVDLARRVFDGLRLKDHSS-WVAMISGLSKNECEAEAIRLFCDMYVLG-IMPTPYAFSSVLSACKKIESLEIGEQLHGLVLKLGFSSDTYVCNALVSLYFHLGNLISAEHIFSNMSQRDAVTYNTLINGLSQCGYGEKAMELFKRMHLDGLEPDSNTLASLVVACSADGTLFRGQQLHAYTTKLGFASNNKIEGALLNLYAKCADIETALDYFLETEVENVVLWNVMLVAYGLLDDLRNSFRIFRQMQIEEIVPNQYTYPSILKTCIRLGDLELGEQIHSQIIKTNFQLNAYVCSVLIDMYAKLGKLDTAWDILIRFAGKDVVSWTTMIAGYTQYNFDDKALTTFRQMLDRGIRSDEVGLTNAVSACAGLQALKEGQQIHAQACVSGFSSDLPFQNALVTLYSRCGKIEESYLAFEQTEAGDNIAWNALVSGFQQSGNNEEALRVFVRMNREGIDNNNFTFGSAVKAASETANMKQGKQ-VHAVITKTGYDSETEVCNALISMYAKCGSISDA 746          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFG--KMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDV---DLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLK 1872
            N SL +G+ +H ++L LGL ++  L + L +FY        A  VF  +    +I  WN ++      ++  E   LF  ++    + P+  T+  VL+AC   G V F   + IH  ++  G     VV + L+ +Y++    D A R+FD +  +D + W  +IS   ++    +A+ LF  M   G  P     ++V+S+C ++  LE G ++H  ++K     D++V +ALV +Y   G L  A+ +F  +  ++ V +N++I   S  G     ++ F+RM+ +G  P   T +S+++ACS    L  G+ +HA+  +    ++  I  +L++LY     + +A + F +    N V WNVM+  Y  + D   +  I+  M+   + PN  T  SIL  C +L  LE G++IH  +I + F+ N  +   L+DMYAK G +D A ++  R   +D VSWT+MI  Y  +    +AL  F +M     + D V L   +SAC+ +  + EG     Q   + G    +   + L+ L  R G++ E+Y   ++T E  +++    L+S    +      L + V++ R  I+ N     + +  ++  A++K+  +V  V  K
Sbjct:   98 NGSLDEGRKLHSQILKLGLDSNGCLSEKLFDFYLFKGDLYGAFKVFDEMPE-RTIFTWNKMIKELASRNLIGEVFGLFVRMVS-ENVTPNEGTFSGVLEACRG-GSVAFDVVEQIHARILYQGLRDSTVVCNPLIDLYSRNGFVDLARRVFDGLRLKDHSSWVAMISGLSKNECEAEAIRLFCDMYVLGIMPTPYAFSSVLSACKKIESLEIGEQLHGLVLKLGFSSDTYVCNALVSLYFHLGNLISAEHIFSNMSQRDAVTYNTLINGLSQCGYGEKAMELFKRMHLDGLEPDSNTLASLVVACSADGTLFRGQQLHAYTTKLGFASNNKIEGALLNLYAKCADIETALDYFLETEVENVVLWNVMLVAYGLLDDLRNSFRIFRQMQIEEIVPNQYTYPSILKTCIRLGDLELGEQIHSQIIKTNFQLNAYVCSVLIDMYAKLGKLDTAWDILIRFAGKDVVSWTTMIAGYTQYNFDDKALTTFRQMLDRGIRSDEVGLTNAVSACAGLQALKEGQQIHAQACVS-GFSSDLPFQNALVTLYSRCGKIEESYLAFEQT-EAGDNIAWNALVSGFQQSGNNEEALRVFVRMNREGIDNNNFTFGSAVKAASETANMKQGKQVHAVITK 720          

Query:  148 IENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPI--KNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIH-RTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            I   SS++ WN  +      +  VE+L LF  + R  +  P+++T+P V KAC  L  VG  +M+H HLIK+ F SD+ V ++ V M+ KCN  D A ++F+ MPERD   WN ++S + Q G   KA  LF +MR +  TP+SVT+ T+I S +    L+    +H   I+  + +   V +  +  YGKCG LD AK VFE I    + VV+WNSM  AYSV G++      +  M RE   P L+TF ++  +C     L  G+ IH+  I    + DI   ++ I +Y  S    SA+ +F+ M     VSW VMISGY + GD   ALA++  M ++G +P+ +T+ S++S C +  +LE GK I  R  I      N ++  AL+DMY+KCG++ EA ++F+  P +  V+WT+MI  Y  +G  LEALKLF +M   + KP+ +T LAVL AC+H G +++G  +F+ M   Y I P ++HYSC++DLLGR G+L EA E++ R    + D  +   L +AC++HRN+ +  + A  L    P   + Y+ ++N YA+   WD   ++R  MK+  ++K PG S I++N K H F VG+  H ++E+
Sbjct:   11 ISGLSSVNAWNLQIREAVNRNDPVESLLLFREMKRGGF-EPNNFTFPFVAKACARLADVGCCEMVHAHLIKSPFWSDVFVGTATVDMFVKCNSVDYAAKVFERMPERDATTWNAMLSGFCQSGHTDKAFSLFREMRLNEITPDSVTVMTLIQSASFEKSLKLLEAMHAVGIRLGVDVQVTVANTWISTYGKCGDLDSAKLVFEAIDRGDRTVVSWNSMFKAYSVFGEAFDAFGLYCLMLREEFKPDLSTFINLAASCQNPETLTQGRLIHSHAIHLGTDQDIEAINTFISMYSKSEDTCSARLLFDIMTSRTCVSWTVMISGYAEKGDMDEALALFHAMIKSGEKPDLVTLLSLISGCGKFGSLETGKWIDARADIYGCKRDNVMICNALIDMYSKCGSIHEARDIFDNTPEKTVVTWTTMIAGYALNGIFLEALKLFSKMIDLDYKPNHITFLAVLQACAHSGSLEKGWEYFHIMKQVYNISPGLDHYSCMVDLLGRKGKLEEALELI-RNMSAKPDAGIWGALLNACKIHRNVKIAEQAAESLFNLEPQMAAPYVEMANIYAAAGMWDGFARIRSIMKQRNIKKYPGESVIQVNGKNHSFTVGEHGHVENEV 622          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIE-NPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDS-FVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHG-KFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKM-PKTNTVSWNVMIS 1104
            SLK  + +H   + LG+     +    I+ Y  C   DSAKLVF++I+    ++  WN +   ++      +A  L+  +LR  +  PD  T+ ++  +C     +  G++IH+H I  G   DI   ++ + MY+K      A  LFD M  R    W  +IS Y + G   +A+ LF  M  SG  P+ VTL ++IS C +   LE G  I           D+  + +AL+DMY KCG +  A+++F+  P K VV W +MIA Y++ G  +  ++ F +M      P   TF ++L AC+ S  L  G ++ H       I   +  YS ++DL    G +  A  +   M  K +   W  +++
Sbjct:  168 SLKLLEAMHAVGIRLGVDVQVTVANTWISTYGKCGDLDSAKLVFEAIDRGDRTVVSWNSMFKAYSVFGEAFDAFGLYCLMLREEF-KPDLSTFINLAASCQNPETLTQGRLIHSHAIHLGTDQDIEAINTFISMYSKSEDTCSARLLFDIMTSRTCVSWTVMISGYAEKGDMDEALALFHAMIKSGEKPDLVTLLSLISGCGKFGSLETGKWIDARADIYGCKRDNVMICNALIDMYSKCGSIHEARDIFDNTPEKTVVTWTTMIAGYALNGIFLEALKLFSKMIDLDYKPNHITFLAVLQACAHSGSLEKGWEYFHIMKQVYNISPGLDHYSCMVDLLGRKGKLEEALELIRNMSAKPDAGIWGALLN 535          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIEN--PSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTG-FVSDIVVASSLVCMYAKC-NVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKC---GCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGD-SISCIQFFRRMNREG-TSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            GKL+H +++   ++ D  L  +LI+ Y        A+ VF+++       +  W+ +M  +  N   ++A+++F   L    + P+ Y Y +V++AC     VG G++    L+KTG F SD+ V  SL+ M+ K  N F+ A ++FD+M E +V  W  +I+   Q G  ++A+  F  M  SGF  +  TL++V S+CA L +L  G ++H   I+  LV D  V  +LVDMY KC   G +D  ++VF+++   +V++W ++I  Y    + +   I  F  M  +G   P   TFSS   AC   +    GK +     +  + ++  + +S+I ++  S  +  A+  FE + + N VS+N  + G  +  ++  A  +  ++ E  +  +A T  S+LS  + + ++ KG++IH  V+      N+ +  AL+ MY+KCG++D A  VFN + NR+ +SWTSMIT +  HG A+  L+ F +M +   KP+ VT +A+LSACSHVGLV EG   FN M  ++ IKP++EHY+C++DLL RAG L +A+E +  T   + DV +  T   ACR+H N +LG   AR ++E +P++ + YI LSN YA   KW+E  ++R KMKE  L K  GCSWIE+  KIH F+VGD +HP +
Sbjct:   81 GKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLV-PNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDD--VECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVVKLGLSCNQPVCNALISMYSKCGSIDTASRVFNFMENRNVISWTSMITGFAKHGFAIRVLETFNQMIEEGVKPNEVTYVAILSACSHVGLVSEGWRHFNSMYEDHKIKPKMEHYACMVDLLCRAGLLTDAFEFI-NTMPFQADVLVWRTFLGACRVHSNTELGKLAARKILELDPNEPAAYIQLSNIYACAGKWEESTEMRRKMKERNLVKEGGCSWIEVGDKIHKFYVGDTAHPNA 736          

Query:  514 GQAQKAMELFEKMRNSGFTP-NSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFE---QIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIR-NIIEADIYIYSSLIDLYFVSG--SVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKC---GAVDEALNVFNRLPNRDPVSWTSMITAYGSH-GQALEALKLFGEM-QQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHS-TYIMLSNTYASVKKWDEVKKVRLKMKELGLRKN-PGCS 1911
            G  + A+   + M   G  P +SVT ++++ SC R  D   G  +H  LI+  +  DS + ++L+ +Y K G    A++VFE   +   ++VV+W++M+A Y   G  +  I+ F      G  P    +++++ ACS S  +  G+    F+++    E+D+ +  SLID+ FV G  S  +A  VF+KM + N V+W +MI+  +++G    A+  + DM  +G   +  T++S+ SAC++L  L  GK++H   I S    +  +  +L+DMYAKC   G+VD+   VF+R+ +   +SWT++IT Y  +   A EA+ LF EM  Q + +P+  T  +   AC ++     G     Q     G+       + +I +  ++ R+ +A    +  SE +  V   + L   CR + N +   K+   + E+     + T+  L +  A+V    + +++  ++ +LGL  N P C+
Sbjct:   40 GDLRGAVSALDLMARDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDM-FVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDD--VECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKR-GLASNSSVANSVISMFVKSDRMEDAQRAFESLSE-KNLVSYNTFLDGTCR-NLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVVKLGLSCNQPVCN 513          

Query:  271 DSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEM---PERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIK-DQLVLDSFVTSALVDMYGKC-GCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLY---FVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDY-FGALAIYDDMKEAG-VRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEI 1662
            DS T+ S+LK+C        GK++H  LI+     D V+ +SL+ +Y+K      A  +F+ M    +RDV  W+ +++CY  +G+   A+++F +    G  PN    T VI +C+    +  G      L+K      D  V  +L+DM+ K     + A +VF+++   NVV W  MI      G     I+FF  M   G      T SS+  AC+    L  GK +H++ IR+ +  D  +  SL+D+Y      GSV   + VF++M   + +SW  +I+GY+K  +    A+ ++ +M   G V PN  T +S   AC  L+    GK++          +N  +  +++ M+ K   +++A   F  L  ++ VS+ + +     +    +A KL  E+ +        T  ++LS  ++VG + +G    +Q++   G+       + LI +  + G ++ A  +
Sbjct:   61 DSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRSGLVDD--VECSLVDMYAKCSADGSVDDCRKVFDRMEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGHVEPNHFTFSSAFKACGNLSDPRVGKQVLGQAFKRGLASNSSVANSVISMFVKSDRMEDAQRAFESLSEKNLVSYNTFLDGTCRNLNFEQAFKLLSEITERELGVSAFTFASLLSGVANVGSIRKGEQIHSQVV-KLGLSCNQPVCNALISMYSKCGSIDTASRV 531          

Query:  793 MIAAYSVTGDSISCIQFFRRMNREGTSPT-LTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKM---PKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGK-EIHRTVIDSEFETNEIMMGALLDMYAKC-GAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRA---GRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDH 1797
            +I  +   GD    +     M R+G  P    TFSS+L +C R+     GK +HA +I   IE D  +Y+SLI LY  SG  + A++VFE M    K + VSW+ M++ Y   G    A+ ++ +  E G+ PN    T+++ ACS    +  G+  +   +    FE++  +  +L+DM+ K   + + A  VF+++   + V+WT MIT     G   EA++ F +M  S  + D  TL +V SAC+ +  +  G    +  I + G+   +E    L+D+  +    G +++  ++  R     ED  ++S         +N +L  +   L  E     H
Sbjct:   32 LILRHLNAGDLRGAVSALDLMARDGIRPMDSVTFSSLLKSCIRARDFRLGKLVHARLIEFDIEPDSVLYNSLISLYSKSGDSAKAEDVFETMRRFGKRDVVSWSAMMACYGNNGRELDAIKVFVEFLELGLVPNDYCYTAVIRACSNSDFVGVGRVTLGFLMKTGHFESDVCVGCSLIDMFVKGENSFENAYKVFDKMSELNVVTWTLMITRCMQMGFPREAIRFFLDMVLSGFESDKFTLSSVFSACAELENLSLGKQLHSWAIRS-GLVDDVE--CSLVDMYAKCSADGSVDDCRKVFDR----MEDHSVMSWTALITGYMKNCNLATEAINLFSEMITQGH 368          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVG-----FGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMP-ERDVACWNTVI 495
            S+++G+ IH +++ LGL  +  +C  LI+ Y  C   D+A  VF  +EN + IS W  ++TGF K+   +  LE F  ++    + P+  TY ++L AC  +G V      F  M  +H IK      +   + +V +  +  +   A    + MP + DV  W T +
Sbjct:  489 SIRKGEQIHSQVVKLGLSCNQPVCNALISMYSKCGSIDTASRVFNFMENRNVIS-WTSMITGFAKHGFAIRVLETFNQMIE-EGVKPNEVTYVAILSACSHVGLVSEGWRHFNSMYEDHKIK----PKMEHYACMVDLLCRAGLLTDAFEFINTMPFQADVLVWRTFL 650          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIG---PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSG--FTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDK 1959
            G  +H  ++  GL  D  +   L++FY +  F   A  +F  +   + +S WN ++  F+ N    E+  L   ++     G   PD  T  +VL  C    ++G GK +H   +K     ++V+ ++L+ MY+KC     A  +F     ++V  WNT++  +  +G      ++  +M   G     + VT+   +  C     L    ++H   +K + V +  V +A V  Y KCG L  A+ VF  I  K V +WN++I  ++ + D    +    +M   G  P   T  S+L ACS+   L  GK +H F+IRN +E D+++Y S++ LY   G + + + +F+ M   + VSWN +I+GY++ G    AL ++  M   G++   I++  +  ACS L +L  G+E H   +    E +  +  +L+DMYAK G++ ++  VFN L  +   SW +MI  YG HG A EA+KLF EMQ++   PD +T L VL+AC+H GL+ EG  + +QM +++G+KP ++HY+C+ID+LGRAG+L++A  ++        DV +  +L S+CR+H+NL++G K+A  L E  P+    Y++LSN YA + KW++V+KVR +M E+ LRK+ GCSWIE+N+K+  F VG++
Sbjct:  206 GLAVHGLVVKTGLVEDVFVGNALVSFYGTHGFVTDALQLFDIMPERNLVS-WNSMIRVFSDNGFSEESFLLLGEMMEENGDGAFMPDVATLVTVLPVCAREREIGLGKGVHGWAVKLRLDKELVLNNALMDMYSKCGCITNAQMIFKMNNNKNVVSWNTMVGGFSAEGDTHGTFDVLRQMLAGGEDVKADEVTILNAVPVCFHESFLPSLKELHCYSLKQEFVYNELVANAFVASYAKCGSLSYAQRVFHGIRSKTVNSWNALIGGHAQSNDPRLSLDAHLQMKISGLLPDSFTVCSLLSACSKLKSLRLGKEVHGFIIRNWLERDLFVYLSVLSLYIHCGELCTVQALFDAMEDKSLVSWNTVITGYLQNGFPDRALGVFRQMVLYGIQLCGISMMPVFGACSLLPSLRLGREAHAYALKHLLEDDAFIACSLIDMYAKNGSITQSSKVFNGLKEKSTASWNAMIMGYGIHGLAKEAIKLFEEMQRTGHNPDDLTFLGVLTACNHSGLIHEGLRYLDQMKSSFGLKPNLKHYACVIDMLGRAGQLDKALRVVAEEMSEEADVGIWKSLLSSCRIHQNLEMGEKVAAKLFELEPEKPENYVLLSNLYAGLGKWEDVRKVRQRMNEMSLRKDAGCSWIELNRKVFSFVVGER 855          

Query:   13 LKQGKLIHQKML-TLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAM----ELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRM--NREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIE---HYSC-LIDLLGRAGRLNEAYEILQRTSE 1680
            ++ G+ IHQ +  +  L+ND  LC  +I  Y  C   D ++ VF ++ +  ++  WN V++ +++N ++ E LE F  ++    + PD +TYP V+KAC  +  VG G  +H  ++KTG V D+ V ++LV  Y        A++LFD MPER++  WN++I  +  +G ++++     E+ E+  +  F P+  TL TV+  CAR  ++  G  +H   +K +L  +  + +AL+DMY KCGC+  A+ +F+    KNVV+WN+M+  +S  GD+       R+M    E       T  + +  C   + L   K +H + ++     +  + ++ +  Y   GS+S A+ VF  +      SWN +I G+ +  D   +L  +  MK +G+ P++ TV S+LSACS+L +L  GKE+H  +I +  E +  +  ++L +Y  CG +     +F+ + ++  VSW ++IT Y  +G    AL +F +M     +  G++++ V  ACS +  +  G     +    Y +K  +E     +C LID+  + G + ++ ++     E
Sbjct:  100 IEMGRKIHQLVSGSTRLRNDDVLCTRIITMYAMCGSPDDSRFVFDALRS-KNLFQWNAVISSYSRNELYDEVLETFIEMISTTDLLPDHFTYPCVIKACAGMSDVGIGLAVHGLVVKTGLVEDVFVGNALVSFYGTHGFVTDALQLFDIMPERNLVSWNSMIRVFSDNGFSEESFLLLGEMMEENGDGAFMPDVATLVTVLPVCAREREIGLGKGVHGWAVKLRLDKELVLNNALMDMYSKCGCITNAQMIFKMNNNKNVVSWNTMVGGFSAEGDTHGTFDVLRQMLAGGEDVKADEVTILNAVPVCFHESFLPSLKELHCYSLKQEFVYNELVANAFVASYAKCGSLSYAQRVFHGIRSKTVNSWNALIGGHAQSNDPRLSLDAHLQMKISGLLPDSFTVCSLLSACSKLKSLRLGKEVHGFIIRNWLERDLFVYLSVLSLYIHCGELCTVQALFDAMEDKSLVSWNTVITGYLQNGFPDRALGVFRQMVLYGIQLCGISMMPVFGACSLLPSLRLG-----REAHAYALKHLLEDDAFIACSLIDMYAKNGSITQSSKVFNGLKE 660          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKN-LINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQ---VGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD-QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNRE-GTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKE-----------AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            ++ GK IH  +   G   D     N L+N Y  C    +   VF  I   + +S WN +++       +  ALE F  +L    + P S+T  SV+ AC  L     +  GK +H + ++ G ++  ++ ++LV MY K      +  L      RD+  WNTV+S   Q+ Q  +A+E   +M   G  P+  T+++V+ +C+ L  L  G ++H   +K+  L  +SFV SALVDMY  C  +   + VF+ +  + +  WN+MIA YS        +  F  M    G     TT + ++ AC RS      + IH F+++  ++ D ++ ++L+D+Y   G +  A  +F KM   + V+WN MI+GYV    +  AL +   M+              ++PN+IT+ +IL +C+ L+AL KGKEIH   I +   T+  +  AL+DMYAKCG +  +  VF+++P ++ ++W  +I AYG HG   EA+ L   M     KP+ VT ++V +ACSH G+VDEG   F  M  +YG++P  +HY+C++DLLGRAGR+ EAY+++             S+L  A R+H NL++G   A+ LI+  P+  S Y++L+N Y+S   WD+  +VR  MKE G+RK PGCSWIE   ++H F  GD SHPQSE
Sbjct:  113 MELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVS-WNSLISSLCSFEKWEMALEAFRCMLD-ENVEPSSFTLVSVVTACSNLPMPEGLMMGKQVHAYGLRKGELNSFII-NTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKNNLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQKNVITWNVIIMAYGMHGNGQEAIDLLRMMMVQGVKPNEVTFISVFAACSHSGMVDEGLRIFYVMKPDYGVEPSSDHYACVVDLLGRAGRIKEAYQLMNMMPRDFNKAGAWSSLLGASRIHNNLEIGEIAAQNLIQLEPNVASHYVLLANIYSSAGLWDKATEVRRNMKEQGVRKEPGCSWIEHGDEVHKFVAGDSSHPQSE 781          

Query:  148 IENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGF-VSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQL---VLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRN-IIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKE-AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQ-----------QSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLI 1776
            I    S   W  ++    ++++  EA+  +  ++    I PD+Y +P++LKA   L  +  GK IH H+ K G+ V  + VA++LV +Y KC  F    ++FD + ER+   WN++IS      + + A+E F  M +    P+S TL +V+++C+ L  +  G+ + K++    L    L+SF+ + LV MYGK G L  +K +      +++V WN+++++       +  +++ R M  EG  P   T SS+L ACS    L  GK +HA+ ++N  ++ + ++ S+L+D+Y     V S + VF+ M       WN MI+GY +      AL ++  M+E AG+  N+ T+  ++ AC +  A  + + IH  V+    + +  +   L+DMY++ G +D A+ +F ++ +RD V+W +MIT Y       +AL L  +MQ           + + KP+ +TL+ +L +C+ +  + +G       I N  +   +   S L+D+  + G L  + ++  +  +  ++V   + +  A  +H N    + + R+++
Sbjct:   56 ISQSRSPEWWIDLLRSKVRSNLLREAVLTYVDMIVLG-IKPDNYAFPALLKAVADLQDMELGKQIHAHVYKFGYGVDSVTVANTLVNLYRKCGDFGAVYKVFDRISERNQVSWNSLISSLCSFEKWEMALEAFRCMLDENVEPSSFTLVSVVTACSNL-PMPEGLMMGKQVHAYGLRKGELNSFIINTLVAMYGKLGKLASSKVLLGSFGGRDLVTWNTVLSSLCQNEQLLEALEYLREMVLEGVEPDEFTISSVLPACSHLEMLRTGKELHAYALKNGSLDENSFVGSALVDMYCNCKQVLSGRRVFDGMFDRKIGLWNAMIAGYSQNEHDKEALLLFIGMEESAGLLANSTTMAGVVPACVRSGAFSRKEAIHGFVVKRGLDRDRFVQNTLMDMYSRLGKIDIAMRIFGKMEDRDLVTWNTMITGYVFSEHHEDALLLLHKMQNLERKVSKGASRVSLKPNSITLMTILPSCAALSALAKGKEIHAYAIKN-NLATDVAVGSALVDMYAKCGCLQMSRKVFDQIPQ--KNVITWNVIIMAYGMHGNGQEAIDLLRMMM 610          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL+ GK +H  + + G+  D  L   L+  Y +C      +L+F  I N   + LWN +M G+TK   F E++ LF  +L    +  +S+T   VLK   ALG V  GK +H  L+K G  S   V +SL+  Y K    D A +LFDE+  RDV  WN++IS Y  +G ++K +ELF+KM   G   +  T+ +++ +CA   D+  G  +H   +K  +   +   + L+DMY KCG LD A  VF+ + ++ VV W S+IAAY+  G S   I+ F  M+REG SP + T +++L AC+ +  L +GK +H ++  N ++++I++ ++L+D+Y   GS+  A +VF +MP  + +SWN MI GY K      AL+++ DM    ++P+  T+  IL AC+ LA+L++GKE+H  ++ + F +++ +  AL+DMY KCG    A  +F+ +P +D ++WT MI  YG HG    A+  F EM+Q+  +PD V+ +++L ACSH GL+DEG  FFN M     +KP++EHY+C++DLL R+G+L  AY+ + ++  I  D  +   L S CR+H ++ L  K+A  + E  P++   Y++L+NTYA  +KW+EVKK+R K+   GL+KNPGCSWIE+  K+H F  G+ SHPQ++
Sbjct:   18 SLQDGKKVHSFICSSGISIDSVLGSKLVFMYVTCGDLREGRLIFDKIRN-EKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLG-VEVNSHTVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKMLYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMDREGVSPDIFTITTVLHACACNGSLENGKDVHNYIRENDMQSNIFVCNALMDMYAKCGSMEDANSVFLEMPVKDIISWNTMIGGYSKNSLPNEALSLFGDMV-LEMKPDGTTLACILPACASLASLDRGKEVHGHILRNGFFSDQQVANALVDMYVKCGVPVLARLLFDMIPTKDLITWTVMIAGYGMHGFGNNAITTFNEMRQAGIEPDEVSFISILYACSHSGLLDEGWRFFNVMQDECNVKPKLEHYACIVDLLARSGKLAMAYKFI-KSMPIEPDATIWGALLSGCRIHHDVKLAEKVAEHVFELEPENTGYYVLLANTYAEAEKWEEVKKLRQKIGRRGLKKNPGCSWIEVKSKVHIFLAGNSSHPQAK 669          

Query:  271 DSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAG 1638
            +S T  S+L+    L  +  GK +H+ +  +G   D V+ S LV MY  C        +FD++    V  WN +++ Y + G  ++++ LF +M + G   NS T++ V+   A L  ++ G  +H  L+K  L   + V ++L+  Y K   +D+A+++F+++  ++V++WNSMI+ Y   G S   ++ F++M   G    L T  SIL AC+    +  G+ +H   ++  +       ++L+D+Y   G +  A  VF+ M     V+W  +I+ Y + G    A+ ++ +M   GV P+  T+T++L AC+   +LE GK++H  + +++ ++N  +  AL+DMYAKCG++++A +VF  +P +D +SW +MI  Y  +    EAL LFG+M     KPDG TL  +L AC+ +  +D G      ++ N G     +  + L+D+  + G
Sbjct:    2 ESRTCCSILQLSAELKSLQDGKKVHSFICSSGISIDSVLGSKLVFMYVTCGDLREGRLIFDKIRNEKVFLWNLMMNGYTKIGDFKESVSLFRQMLDLGVEVNSHTVSCVLKCFAALGSVKEGKWVHGFLLKLGLGSYNAVVNSLIAFYLKIRRVDVARKLFDELSNRDVISWNSMISGYVANGFSEKGVELFKKMLYLGVDMDLATMVSILQACANCGDVSLGRAVHGSGVKACVHWKTTFCNTLLDMYAKCGVLDGAILVFDLMSVRTVVTWTSLIAAYAREGLSDEAIRLFHEMDREGVSPDIFTITTVLHACACNGSLENGKDVHNYIRENDMQSNIFVCNALMDMYAKCGSMEDANSVFLEMPVKDIISWNTMIGGYSKNSLPNEALSLFGDM-VLEMKPDGTTLACILPACASLASLDRGKEVHGHILRN-GFFSDQQVANALVDMYVKCG 455          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTG-FVSDIVVASSLVCMYAKCNV-FDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKC---GCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGD-SISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            +++ + G L+H ++   GL+ D  +  +LI+ Y  C     A  +F+S+ N   +  W+ +++ +  N    EA+  F  +L   +  P+ Y +  V +AC     +  GK+I   L+KTG F SD+ V  +L+ M+ K N   + A ++FD MP+R+V  W  +I+ + Q G ++ A++LF  M  SG+ P+  TL+ V+S+CA +  L  G + H  ++K  L LD  V  +LVDMY KC   G +D A++VF+++P+ NV++W ++I  Y  +G      I+ F  M +    P   TFSS+L AC+  + +  G+ ++A +++  + +   + +SLI +Y   G++ +A+  F+ + + N VS+N +++ Y K  +   A  ++++++ AG   NA T  S+LS  S + A+ KG++IH  ++ S F++N  +  AL+ MY++CG ++ A  VFN + + + +SWTSMIT +  HG A  AL+ F +M ++   P+ VT +AVLSACSHVGL+ EG   F  M   +GI PR+EHY+C++DLLGR+G L EA E++  +   + D  +L T   ACR+H N+DLG   A +++E++P D + YI+LSN +AS  +W+EV ++R KMKE  L K  GCSWIE+  K+H F+VGD SHPQ++
Sbjct:  161 SHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFY-PNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDIWLGEQVYALVVKMRLASINCVGNSLISMYSRCGNMENARKAFDVLFEKNLVSYNTIVNAYAKSLNSEEAFELFNEIEGAGTGVNAFTFASLLSGASSIGAIGKGEQIHSRILKSGFKSNLHICNALISMYSRCGNIEAAFQVFNEMGDGNVISWTSMITGFAKHGFATRALETFHKMLEAGVSPNEVTYIAVLSACSHVGLISEGLKHFKSMKVEHGIVPRMEHYACVVDLLGRSGHLEEAMELV-NSMPFKADALVLRTFLGACRVHGNMDLGKHAAEIILEQDPHDPAAYILLSNLHASAGQWEEVAEIRKKMKERNLTKEAGCSWIEVENKVHKFYVGDTSHPQAQ 822          

Query:  268 PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEM-PERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIK-DQLVLDSFVTSALVDMYGK-CGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLY---FVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDY-FGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSE 1680
            PD  TY  +LK+C        G ++H+ L ++G   D V+ +SL+ +Y+KC  +  A  +F+ M  +RD+  W+ +ISCY  + +A +A+  F  M   GF PN    T V  +C+   ++  G  I   L+K      D  V  AL+DM+ K  G L+ A +VF+++P +NVV W  MI  +   G S   +  F  M   G  P   T S ++ AC+    L  G+  H  ++++ ++ D+ +  SL+D+Y      GSV  A+ VF++MP  N +SW  +I+GYV+ G     A+ ++ +M +  V+PN  T +S+L AC+ L+ +  G++++  V+     +   +  +L+ MY++CG ++ A   F+ L  ++ VS+ +++ AY     + EA +LF E++ +    +  T  ++LS  S +G + +G    ++++ + G K  +   + LI +  R G +  A+++     +
Sbjct:  146 PDLITYSLLLKSCIRSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDIWLGEQVYALVVKMRLASINCVGNSLISMYSRCGNMENARKAFDVLFEKNLVSYNTIVNAYAKSLNSEEAFELFNEIEGAGTGVNAFTFASLLSGASSIGAIGKGEQIHSRILKS-GFKSNLHICNALISMYSRCGNIEAAFQVFNEMGD 622          

Query:  523 QKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIR-NIIEADIYIYSSLIDLYFV-SGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKC---GAVDEALNVFNRLPNRDPVSWTSMITAY-GSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSC----LIDLLGRAGRLNEA 1653
            +KA+   ++M   G  P+ +T + ++ SC R  + + G  +H  L +  L LDS + ++L+ +Y KCG    A E+FE +  K ++V+W+++I+ Y+    +   I  F  M   G  P    F+ +  ACS    +  GK I  F+++    E+D+ +  +LID++   +G + SA  VF++MP  N V+W +MI+ + ++G    A+ ++ DM  +G  P+  T++ ++SAC+++  L  G++ H  V+ S  + +  +  +L+DMYAKC   G+VD+A  VF+R+P  + +SWT++IT Y  S G   EA++LF EM Q   KP+  T  +VL AC+++  +     +  + +    +K R+   +C    LI +  R G +  A
Sbjct:  130 KKAISTLDQMSLQGTHPDLITYSLLLKSCIRSHNYQLGHLVHHRLTQSGLELDSVILNSLISLYSKCGDWQQAHEIFESMGNKRDLVSWSALISCYANNEKAFEAISAFFDMLECGFYPNEYCFTGVFRACSNKENISLGKIIFGFLLKTGYFESDVCVGCALIDMFVKGNGDLESAYKVFDRMPDRNVVTWTLMITRFQQLGFSRDAVDLFLDMVLSGYVPDRFTLSGVVSACAEMGLLSLGRQFHCLVMKSGLDLDVCVGCSLVDMYAKCVADGSVDDARKVFDRMPVHNVMSWTAIITGYVQSGGCDREAIELFLEMVQGQVKPNHFTFSSVLKACANLSDI-----WLGEQVYALVVKMRLASINCVGNSLISMYSRCGNMENA 512          

Query:   25 KLIHQ---KMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            K +HQ   +++  GL N+      LI+ +        A  VF+ IE+    +L++ ++ G+ K+     AL  F S +++  + P  Y +  +LK CG    +  GK IH  +I +GF  ++   + +V MYAKC   + A  +FD MPERD+ CWNT+IS Y Q+G A+ A+ L  +M   G  P+S+T+ +++ + A    L  GM +H  +++        V++ALVDMY KCG + +A+ +F+ +  + VV+WNSMI  Y  +GD+   +  F++M  EG  PT  T    L AC+    L  GKF+H  + +  +++D+ + +SLI +Y     V  A ++F+ +     VSWN MI GY + G    AL  + +M+   ++P++ T+ S++ A ++L+   + K IH  VI    + N  +M AL+DMYAKCGA+  A  +F+ +  R  ++W +MI  YG+HG    +++LF EM++   KP+ +T L  LSACSH GLV+EG  FF  M  +YGI+P ++HY  ++DLLGRAGRLN+A++ +Q+   I+  + +   +  AC++H+N+DLG K A  + + NPDD   +++L+N YA+   W +V KVR  M++ GL+K PGCS +EI  ++H F+ G  SHPQS+
Sbjct:   54 KEVHQILPQIIKNGLYNETLFQTKLISLFCKYGNLTEASRVFEPIEDKFD-ALYHTMLKGYAKSSSLDSALSFF-SRMKHDSVRPVVYNFTYLLKLCGDNSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPERDLVCWNTMISGYAQNGFAKVALMLVLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKMLDEGVQPTNVTVMGALHACADLGDLERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEEGLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQK-MPIKPGITVYGAMLGACKIHKNVDLGEKAAFEIFKLNPDDGGYHVLLANIYATASMWGKVAKVRTIMEKSGLQKTPGCSLVEIGNEVHSFYSGTTSHPQSK 704          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIG--PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVT--SALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTV-IDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGS 1419
            N+ LK+GK IH  ++T G   +      ++N Y  C   + A  +F  +     +  WN +++G+ +N     AL L   +LR    G  PDS T  S+L A      +  G  +H ++++ GF S + V+++LV MY+KC     A  +FD M  R V  WN++I  Y Q G A+ AM +F+KM + G  P +VT+   + +CA L DLERG  +HK  + DQL LDS V+  ++L+ MY KC  +D+A ++F+ +  K +V+WN+MI  Y+  G     +  F  M      P   T  S++ A +  +     K+IH  +IR  ++ ++++ ++L+D+Y   G++ +A+ +F+ M   + ++WN MI GY   G    ++ ++ +MK+  ++PN IT    LSACS    +E+G     ++  D   E      GA++D+  + G +++A +   ++P +        IT YG+
Sbjct:  151 NSDLKRGKEIHGSVITSGFSWNLFAMTGVVNMYAKCRQINDAYNMFDRMPE-RDLVCWNTMISGYAQNGFAKVALML---VLRMSEEGHRPDSITIVSILPAVADTRLLRIGMAVHGYVLRAGFESLVNVSTALVDMYSKCGSVSIARVIFDGMDHRTVVSWNSMIDGYVQSGDAEGAMLIFQKMLDEGVQPTNVTVMGALHACADLGDLERGKFVHK--LVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVSWNAMILGYAQNGCVNEALNAFCEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEEGLCFFESMKKDYGIEPTMDHYGAMVDLLGRAGRLNQAWDFIQKMPIKPG------ITVYGA 615          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD---QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSV 813
            L++GK +H+ +  L L +D ++  +LI+ Y  C   D A  +F+++ N + +S WN ++ G+ +N    EAL  F   ++   I PDS+T  SV+ A   L      K IH  +I+     ++ V ++LV MYAKC     A +LFD M  R V  WN +I  Y   G  + ++ELF++M+     PN +T    +S+C+    +E G+   + + KD   +  +D +   A+VD+ G+ G L+ A +  +++PIK  +  + +M+ A  +
Sbjct:  356 LERGKFVHKLVDQLKLDSDVSVMNSLISMYSKCKRVDIAADIFKNLRNKTLVS-WNAMILGYAQNGCVNEALNAF-CEMQSRNIKPDSFTMVSVIPALAELSIPRQAKWIHGLVIRRFLDKNVFVMTALVDMYAKCGAIHTARKLFDMMNARHVITWNAMIDGYGTHGLGKTSVELFKEMKKGTIKPNDITFLCALSACSHSGLVEEGLCFFESMKKDYGIEPTMDHY--GAMVDLLGRAGRLNQAWDFIQKMPIKPGITVYGAMLGACKI 622          

Query:    1 MNNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            +   L  GK +H  ++  G  +D  +  +L+  Y  C     A+ +F +I + S +S WN + + +  + M  EA+ LF  ++    I P+ ++  S++  C  L     G+ IH +LIK G+ SD   A++LV MYAK  + + A  +FDE+ + D+  WN +I+         +A+EL  +M  SG  PN  TL++ + +CA +   E G ++H  LIK  +  DSF+   L+DMY KC  +D A+ VF+ +P ++++AWN++I+ +S   +       F  M+ EG     TT S++L + +        + IHA  +++  E D Y+ +SLID Y   G V  A  VFE+ P  + V +  +++ Y + G    AL +Y +M++ G++P++   +S+L+AC+ L+A E+GK++H  ++   F ++     +L++MYAKCG++++A   F+R+P R  VSW++MI     HG   EAL+LF +M +    P+ +TL++VL AC+H GLV E  H+FN M   +GI+P  EHY+C+IDLLGRAG+L  A E++ +    + +  +   L  A R+H+N+DLG + A +L+   P+   T+++L+N YASV  WD+V +VR  MK+  ++K PG SW+E+  K++ F VGD+SH +S
Sbjct:   94 VTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVS-WNALFSCYVHSDMHGEAVSLFHDMV-LSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFPLMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGFEFDNYVVNSLIDTYGKCGHVEDATRVFEESPTVDLVLFTSLVTAYAQDGQGEEALRLYLEMQDRGIKPDSFVCSSLLNACASLSAYEQGKQVHVHILKFGFMSDIFAGNSLVNMYAKCGSIEDASCAFSRIPVRGIVSWSAMIGGLAQHGYGKEALQLFKQMLKVGVPPNHITLVSVLCACNHAGLVAEAKHYFNSMKILFGIEPMQEHYACMIDLLGRAGKLEAAMELVNK-MPFQANALVWGALLGAARIHKNIDLGEQAAEMLLALEPEKSGTHVLLANIYASVGMWDKVARVRRLMKDGKVKKEPGMSWLEVKDKVYTFIVGDRSHSRS 748          

Query:   31 IHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEA 1653
            IH +++  GL  DP +   L+N Y  C     A+ +      P  +S W+ +++G+++N    EA+  F  +     I  + + +PSVLKAC     +  GK +H  ++ TGF SD  VA+SLV +YAKC  F  A  LFD +P+R V  WN + SCY       +A+ LF  M  SG  PN  +L+++I+ C  L D  +G KIH  LIK     D+F  +ALVDMY K G L+ A  VF++I   ++V+WN++IA   +       ++  R MN+ G  P + T SS L AC+  A    G+ +H+ +I+  + +D ++   LID+Y    S+  A+ VF+ MP+ + ++WN +ISG+ +  +   A +++  M   G+  N  T++++L + + L A    ++IH   + S FE +  ++ +L+D Y KCG V++A  VF   P  D V +TS++TAY   GQ  EAL+L+ EMQ    KPD     ++L+AC+ +   ++G    +  I  +G    I   + L+++  + G + +A
Sbjct:    3 IHARVIKFGLSQDPKIRNYLVNLYSKCQLFGYARKLLDRSTEPDLVS-WSALISGYSQNGFCQEAVLAFYEM-HLLGIKCNEFAFPSVLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLIKMDMGSDSFLGVGLIDMYSKCNSMDDARLVFKLMPERDMIAWNAVISGHSQNEEDEEAASLFPLMHTEGIGFNQTTLSTVLKSIAALQANYMCRQIHALSLKSGFEFDNYVVNSLIDTYGKCGHVEDATRVFEESPTVDLVLFTSLVTAYAQDGQGEEALRLYLEMQDRGIKPDSFVCSSLLNACASLSAYEQGKQ-VHVHILKFGFMSDIFAGNSLVNMYAKCGSIEDA 540          

Query:  637 MKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMI 1569
            M+IH  +IK  L  D  + + LV++Y KC     A+++ ++    ++V+W+++I+ YS  G     +  F  M+  G       F S+L AC+ +  L+ GK +H  ++    ++D ++ +SL+ LY   G    A+++F+ +P  + VSWN + S YV    +  A++++ DM  +G+RPN  +++S+++ C+ L    +G++IH  +I   ++++     AL+DMYAK G +++A +VF+ +   D VSW ++I     H     AL+L  EM +S   P+  TL + L AC+ + L + G    + +I
Sbjct:    1 MEIHARVIKFGLSQDPKIRNYLVNLYSKCQLFGYARKLLDRSTEPDLVSWSALISGYSQNGFCQEAVLAFYEMHLLGIKCNEFAFPSVLKACTVTKDLVLGKQVHGIVVVTGFDSDEFVANSLVILYAKCGGFGDARSLFDAIPDRSVVSWNALFSCYVHSDMHGEAVSLFHDMVLSGIRPNEFSLSSMINVCTGLEDSVQGRKIHGYLIKLGYDSDAFSANALVDMYAKVGILEDASSVFDEIAKPDIVSWNAIIAGCVLHEYHHRALELLREMNKSGMCPNMFTLSSALKACAGMALRELGRQLHSSLI 311          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIR-NIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKE-AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            L+Q K  H  ++  G   D  L   ++N Y        A   F  + N   +  WN +   +  +  F EAL  F        + PD YT+P V+KACG L     GK IH  ++K GF  D+ VA+SLV MY++  +   A +LFD+MP RD   WN +IS Y Q+G A +A+++ ++MR  G   +++T+ +V+  CA++ D+  G  IH  +IK  L  + FV++AL++MY K G L  A++VF Q+ ++++V+WNS+IAAY    + +S   FF +M      P L T  S+    ++     + + +H F++R       I I ++++D+Y   G++ SA+ VF  +   + VSWN +I+GY + G    A+ +Y  M+E   + PN  T  SIL A S + AL++G  IH  VI +   ++  +   L+DMY KCG +D+A+++F ++P ++ V W +MI+ YG HG   +AL+LF EM+    KPD +T +++LSACSH GLV +    FN M   YGIKP ++HY C++DL GRAG L  A+  +++   I+ D      L +ACR+H N++LG   +  L E + ++   Y++LSN YA+V KW+ V  VR   ++ GLRKNPG S I +N K+  F+ G+++HP+ E
Sbjct:   15 LQQVKCAHTLVVVSGRFKDNFLSSKIVNLYSQHGDVSLAWWTFHHLPN-KDVYTWNSMAFAYVSHGRFCEALGCFNQFFSTSGLRPDFYTFPPVVKACGDLLD---GKKIHCLVLKLGFEWDVFVAASLVHMYSRFGLVGDARKLFDDMPARDRGSWNAMISGYCQNGNAAEALDIADEMRLEGVKMDAITVASVLPVCAQVGDILSGKLIHLYVIKHGLEFELFVSNALINMYAKFGSLGHAQKVFGQMVVRDIVSWNSIIAAYEQNNNPVSAHLFFHKMQEARVQPDLLTLVSLASIVAQLNDHQNSRSVHGFVMRKGWFMEYIIIGNAVVDMYAKIGNLDSARAVFGGLLIKDVVSWNTLITGYAQNGLASEAIEVYLLMEEHEEIIPNQGTWVSILPAYSHVGALQQGMRIHGQVIKNCLYSDVFVGTCLIDMYGKCGKLDDAISLFYQVPRKNSVPWNAMISCYGVHGDGEKALELFREMKAERVKPDHITFVSLLSACSHSGLVSDAQWCFNMMEEEYGIKPSLKHYGCMVDLFGRAGELEMAFNFIKK-MPIQPDASAWGALLNACRIHGNIELGKHASERLFEVDSENVGYYVLLSNIYANVGKWEGVDDVRSLARDRGLRKNPGWSSIILNNKVDVFYTGNQTHPKCE 666          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            + +G  IH  ++  G  +   +  +L++ Y  C+    A+ +F  +   + +  WN +++ ++ N   +EAL LF  + +   +G ++YT  + L+AC        G  IH  ++K+  V D+ VA++LV M+ +      A R+FDE+ E+D   WN++I+ + Q+G   +A++ F  ++++   P+ V+L +++++  RL  L  G +IH   +K+ L  +  + + L+DMY KC C+  A  VF+++  K++++W ++IAAY+        ++  R++  +G         S LLACS    L H K +H + ++  + +D+ + + +ID+Y   G+++ A  +FE +   + VSW  MIS YV  G    AL ++  MKE  V P++IT+ SILSA + L+AL KGKEIH  +    F      + +L+DMYA CG+++ A  VF    ++  V WT+MI AYG HG+   A++LF  M+     PD +T LA+L ACSH GL++EG      M   Y ++P  EHY+CL+DLLGRA  L EAY  + ++ +I    ++      ACR+H N  LG   A+ L++ +PD   +Y+++SN +A+  +W +V++VR++MK  GL+KNPGCSWIE+  K+H F V DKSHP+S
Sbjct:   57 IHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAG-VGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGLQDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRKVQTKGMDVDTMMIGSTLLACSGLRCLSHAKEVHGYTLKRGL-SDLMMQNMIIDVYADCGNINYATRMFESIKCKDVVSWTSMISCYVHNGLANEALGVFYLMKETSVEPDSITLVSILSAAASLSALNKGKEIHGFIFRKGFMLEGSTVNSLVDMYACCGSLENAYKVFICTRSKSLVLWTTMINAYGMHGRGKAAVELFSIMEDQKLIPDHITFLALLYACSHSGLINEGKRLLETMKCKYQLEPWPEHYACLVDLLGRANHLEEAYHFV-KSMQIEPTAEVWCAFLGACRIHSNKKLGEIAAQKLLDLDPDSPGSYVLISNVFAASGRWKDVEEVRMRMKGGGLKKNPGCSWIEVGNKVHTFLVRDKSHPES 707          

Query:  163 SISLWNGVMTGFTKNHMFVEALELFESL--LRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLL-IEKNPDDHSTYIML 1815
            +I  WN +M     N   + ALELF  +  L  P+   DS+T+P VLKACG +  +  G  IH  +IK G+ S + VA+SLV MYAKCN    A +LFD M ER DV  WN++IS Y  +GQ  +A+ LF +M+ +G   N+ TL   + +C      + GM+IH  ++K   VLD +V +ALV M+ + G +  A  +F+++  K+ + WNSMIA ++  G     +QFF  +      P   +  SIL A  R   LL+GK IHA+ ++N +++++ I ++LID+Y     V+ A  VF+KM   + +SW  +I+ Y +   +  AL +   ++  G+  + + + S L ACS L  L   KE+H   +     ++ +M   ++D+YA CG ++ A  +F  +  +D VSWTSMI+ Y  +G A EAL +F  M++++ +PD +TL+++LSA + +  +++G    +  I   G        + L+D+    G L  AY++   T    + + L +T+ +A  +H      V++  ++  +K   DH T++ L
Sbjct:    5 TIFTWNAMMGANVSNGEPLRALELFREMRVLGVPF---DSFTFPCVLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGLQDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRKVQTKGMDVDTMMIGSTLLACSGLRCLSHAKEVHGYTLKRGL-SDLMMQNMIIDVYADCGNINYATRMFESIKCKDVVSWTSMISCYVHNGLANEALGVFYLMKETSVEPDSITLVSILSAAASLSALNKGKE-IHGFIFRKGFMLEGSTVNSLVDMYACCGSLENAYKVFICTRS--KSLVLWTTMINAYGMHGRGKAAVELFSIMEDQKLIPDHITFLAL 552          

Query:  457 MPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKN-VVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEH---YSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLS-TLFSACRLHRNL-DLGVKIARLLIEKNPD-DHSTYIMLSNTYASVKKWDEVKKV 1863
            M +R +  WN ++     +G+  +A+ELF +MR  G   +S T   V+ +C  + D+ RG +IH  +IK       FV ++LV MY KC  +  A+++F+++  +N VV+WNS+I+AYS+ G  +  +  FR M + G      T  + L AC  S+    G  IHA ++++    D+Y+ ++L+ ++   G +S A  +F+++ + + ++WN MI+G+ + G Y  AL  +  +++A ++P+ +++ SIL+A  +L  L  GKEIH   + +  ++N  +   L+DMY+KC  V  A  VF+++ N+D +SWT++I AY  +    EALKL  ++Q      D + + + L ACS +      C    + +  Y +K  +      + +ID+    G +N A     R  E  +  D++S T   +C +H  L +  + +  L+ E + + D  T + + +  AS+   ++ K++
Sbjct:    1 MHDRTIFTWNAMMGANVSNGEPLRALELFREMRVLGVPFDSFTFPCVLKACGVVEDIHRGAEIHGLIIKCGYDSIVFVANSLVSMYAKCNDILGARKLFDRMNERNDVVSWNSIISAYSLNGQCMEALGLFREMQKAGVGANTYTLVAALQACEDSSFKKLGMEIHAAILKSNQVLDVYVANALVAMHVRFGKMSYAARIFDELDEKDNITWNSMIAGFTQNGLYNEALQFFCGLQDANLKPDEVSLISILAASGRLGYLLNGKEIHAYAMKNWLDSNLRIGNTLIDMYSKCCCVAYAGLVFDKMINKDLISWTTVIAAYAQNNCHTEALKLLRKVQTKGMDVDTMMIGSTLLACSGL-----RCLSHAKEVHGYTLKRGLSDLMMQNMIIDVYADCGNINYA----TRMFESIKCKDVVSWTSMISCYVHNGLANEALGVFYLMKETSVEPDSITLVSILSAAASLSALNKGKEI 467          

Query:   10 SLKQGKLIHQKMLTLG-LQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSIS---LWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGA-LGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SLK+G+++H  ++ +  L +   L  NLI FY  C     AKLVF+++++ + +S   L +G+    +K   FV  LELF  ++    + PD++T+P V  A    LG     + +H   IKT  + D+ V SSLV  Y K      A +LFD MPER++  W T+IS Y     A++A+ +F  MR      N    T+V+S+      ++ G ++H  ++K+ ++    V +ALV MY KCG L+ +  +FE    KN + W+++I  YS  GDS   ++ F +M+  G  P+  T   +L ACS  A +  GK  H +++++  E  IY  ++L+D+Y   G    A+  F+ + + + V W  +I+GYV+ G    AL++Y  M+   + PN +T+ S+L ACS LAALE+GK+IH   I         +  AL  MYAKCG+++E + +F R+  RD VSW +MI+    +G   EAL+LF EM+    KPD +T + VLSACSH+G+V  G  +FN M   +G+ PR+EHY+C++D+L RAG+LNEA E ++ ++ I   + L   L  ACR H N +LG      L+E    + S Y++LS+ Y ++ +  +V +VR  MK  G+RK  GCSWIE+   +H F VGD+ HPQ E
Sbjct:   22 SLKKGQILHAHIIKIPYLSSCNYLANNLIKFYAKCGHLHGAKLVFENLKHKNVVSYNCLIHGLSHNGSKGSNFV--LELFRRMIANNIL-PDAHTFPGVFTAAALNLGCNFDARQVHVLGIKTASIDDVFVGSSLVNFYCKVGCVFEARKLFDRMPERNLVSWTTMISGYASKQMAKEALGVFGLMRLVEGNLNEFVFTSVLSALVCPEFVDSGKQVHCVVVKNGVLEFVSVLNALVTMYAKCGNLNYSLMLFEMCSDKNAITWSALITGYSQAGDSHKALKLFSKMHYAGFVPSEFTLVGVLKACSDVAAIEEGKQTHGYLLKSGYETQIYTATALVDMYAKFGFTGDARKGFDFLLEPDLVLWTSIIAGYVQNGKNEEALSMYGRMQMRKILPNELTMASVLKACSNLAALEQGKQIHARTIKYGLGPELSIRSALSTMYAKCGSLEEGVLIFRRMLQRDIVSWNAMISGLSQNGHGREALELFEEMRLEGTKPDHITFVTVLSACSHMGIVKRGWAYFNMMFDEFGLVPRVEHYACMVDVLSRAGKLNEAKEFIE-SAIIDHGMCLWRILLPACRNHCNYELGAYAGEKLMELGSRESSAYVLLSSIYTAMGRLADVVRVRRMMKVRGVRKETGCSWIELKSHVHVFVVGDQIHPQIE 678          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSG--FTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMG-ALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVD--LLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            ++ G++IH  ++ +GL  D  +   L+  Y  C   D A  VF  +   + +S WN ++  F++N    ++ +L   +L    + PD  T  ++L  C   G+V  G  IH   +K G   +++V +++V MY+KC   + A   F +   ++V  WNT+IS +  +G   +A  L ++M+  G     N VT+  V+ +C     L    ++H    +        +++A +  Y KCG L+ A++VF  I  K V +WN++I  ++  GD    +    +M   G  P   T SS+LLAC+    L +GK IH +++RN +E D ++ +SL+  Y   G  SSA+ +F++M   N VSWN MISGY + G  + +LA++      G++ + I + S+  ACSQL+AL  GKE H  V+ +  +T +  +G +++DMYAK G + E+  VF+ L +++  SW ++I A+G HG   EA++L+  M++    PD  T + +L AC H GLV+EG  +F +M     I+P++EHY+CLID+L RAGRL++A   L+  +E+ E+ D  + S+L  +CR    L++G K+A+ L+E  PD    Y++LSN YA + KWD V++VR  MKE+GL+K+ GCSWIE+  +++ F VGD   P+S
Sbjct:   75 VRLGEVIHGMVIKMGLVLDVFVGNALVGMYGKCGAVDEAMKVFDFMPETNLVS-WNSMICAFSENGFSRDSFDLLMEMLGEEGLLPDVVTVVTILPVCAGEGEVDIGMGIHGLAVKLGLSEEVMVNNAMVYMYSKCGYLNEAQMSFVKNNNKNVVSWNTMISAFSLEGDVNEAFNLLQEMQIQGEEMKANEVTILNVLPACLDKLQLRSLKELHGYSFR-HCFQHVELSNAFILAYAKCGALNSAEKVFHGIGDKTVSSWNALIGGHAQNGDPRKALHLLFQMTYSGQQPDWFTISSLLLACAHLKSLQYGKEIHGYVLRNGLETDFFVGTSLLSHYIHCGKASSARVLFDRMKDKNLVSWNAMISGYSQNGLPYESLALFRKSLSEGIQSHEIAIVSVFGACSQLSALRLGKEAHGYVLKA-LQTEDAFVGCSIIDMYAKSGCIKESRKVFDGLKDKNVASWNAIIVAHGIHGHGKEAIELYERMKKVGQMPDRFTYIGILMACGHAGLVEEGLKYFKEMQNFNLIEPKLEHYACLIDMLARAGRLDDA---LRLVNEMPEEADNRIWSSLLRSCRTFGALEIGEKVAKKLLELEPDKAENYVLLSNLYAGLGKWDGVRRVRQMMKEIGLQKDAGCSWIEVGGRVYSFVVGDSLQPKS 727          

Query:  100 YFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAME-LFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREG--TSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSC-LIDLLGRAGRLNEAYEI 1662
            Y  C     ++LVF ++E  + I  WN +++G+T+N ++ + +++F  L+      PD++T+PSV+KACG +  V  G++IH  +IK G V D+ V ++LV MY KC   D A+++FD MPE ++  WN++I  + ++G ++ + + L E +   G  P+ VT+ T++  CA   +++ GM IH   +K  L  +  V +A+V MY KCG L+ A+  F +   KNVV+WN+MI+A+S+ GD        + M  +G        T  ++L AC    QL   K +H +  R+  +  + + ++ I  Y   G+++SA+ VF  +      SWN +I G+ + GD   AL +   M  +G +P+  T++S+L AC+ L +L+ GKEIH  V+ +  ET+  +  +LL  Y  CG    A  +F+R+ +++ VSW +MI+ Y  +G   E+L LF +      +   + +++V  ACS +  +  G      ++    ++       C +ID+  ++G + E+ ++
Sbjct:    2 YAMCGSPLDSRLVFDNMETKNLIQ-WNALVSGYTRNGLYGDVVKVFMDLVSDTDFQPDNFTFPSVIKACGGILDVRLGEVIHGMVIKMGLVLDVFVGNALVGMYGKCGAVDEAMKVFDFMPETNLVSWNSMICAFSENGFSRDSFDLLMEMLGEEGLLPDVVTVVTILPVCAGEGEVDIGMGIHGLAVKLGLSEEVMVNNAMVYMYSKCGYLNEAQMSFVKNNNKNVVSWNTMISAFSLEGDVNEAFNLLQEMQIQGEEMKANEVTILNVLPACLDKLQLRSLKELHGYSFRHCFQ-HVELSNAFILAYAKCGALNSAEKVFHGIGDKTVSSWNALIGGHAQNGDPRKALHLLFQMTYSGQQPDWFTISSLLLACAHLKSLQYGKEIHGYVLRNGLETDFFVGTSLLSHYIHCGKASSARVLFDRMKDKNLVSWNAMISGYSQNGLPYESLALFRKSLSEGIQSHEIAIVSVFGACSQLSALRLGKEAHGYVLK--ALQTEDAFVGCSIIDMYAKSGCIKESRKV 522          

Query:  709 MYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRM-NREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVG---DYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEM--QQSNAKPDGVTLLAVLSAC 1518
            MY  CG    ++ VF+ +  KN++ WN++++ Y+  G     ++ F  + +     P   TF S++ AC     +  G+ IH  +I+  +  D+++ ++L+ +Y   G+V  A  VF+ MP+TN VSWN MI  + + G   D F  L   + + E G+ P+ +TV +IL  C+    ++ G  IH   +        ++  A++ MY+KCG ++EA   F +  N++ VSW +MI+A+   G   EA  L  EM  Q    K + VT+L VL AC
Sbjct:    1 MYAMCGSPLDSRLVFDNMETKNLIQWNALVSGYTRNGLYGDVVKVFMDLVSDTDFQPDNFTFPSVIKACGGILDVRLGEVIHGMVIKMGLVLDVFVGNALVGMYGKCGAVDEAMKVFDFMPETNLVSWNSMICAFSENGFSRDSFDLL--MEMLGEEGLLPDVVTVVTILPVCAGEGEVDIGMGIHGLAVKLGLSEEVMVNNAMVYMYSKCGYLNEAQMSFVKNNNKNVVSWNTMISAFSLEGDVNEAFNLLQEMQIQGEEMKANEVTILNVLPAC 274          

Query: 1012 LYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDM-KEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEM-QQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEA 1653
            +Y + GS   ++ VF+ M   N + WN ++SGY + G Y   + ++ D+  +   +P+  T  S++ AC  +  +  G+ IH  VI      +  +  AL+ MY KCGAVDEA+ VF+ +P  + VSW SMI A+  +G + ++  L  EM  +    PD VT++ +L  C+  G VD G    + +    G+   +   + ++ +  + G LNEA
Sbjct:    1 MYAMCGSPLDSRLVFDNMETKNLIQWNALVSGYTRNGLYGDVVKVFMDLVSDTDFQPDNFTFPSVIKACGGILDVRLGEVIHGMVIKMGLVLDVFVGNALVGMYGKCGAVDEAMKVFDFMPETNLVSWNSMICAFSENGFSRDSFDLLMEMLGEEGLLPDVVTVVTILPVCAGEGEVDIGMG-IHGLAVKLGLSEEVMVNNAMVYMYSKCGYLNEA 215          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADI-YIYSSLIDLYFVSGSVSSAKNVFEKM--PKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNR-DPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSH 1965
            +L  G L+H + L  GL ++  +  +L++ Y  C   ++AK VF ++ N  ++ LWN ++ G+ +N    E +ELF ++    +  PD +TY S+L AC  L  +  G  +H+ +IK  F S++ V ++LV MYAK    + A + F+ +  RD   WN +I  Y Q+    +A  LF +M   G  P+ V+L +++S+CA +  LE+G ++H   +K       +  S+L+DMY KCG +D A ++   +P ++VV+ N++IA Y+        +  FR M  EG + T  TF+S+L AC    +L  G+ IH  +++  ++ D  ++  SL+ +Y  S   + A  +F +   PK+  V W  MISG  +      AL +Y +M+   V P+  T  S L AC+ +++++ G E H  +  + F+++E+   AL+DMYAKCG V  ++ VF  +  + D +SW SMI  +  +G A +AL++F EM+QS+  PD VT L VL+ACSH G V EG   F+ M+  YG++PR +H +C++DLLGR G L EA E + + +    D  + +T+  ACR+H +   G + A  LIE  P + S Y++LSN YA+   WDEV  +R +M+E G++K PGCSWI + ++ + F  GDKSH
Sbjct:  342 ALDFGLLVHAEALKQGLHSNVYVGSSLVSMYAKCGKMEAAKKVFDTL-NEQNVVLWNAMLGGYVQNGYANEVMELFFNMKSCGFY-PDDFTYSSILSACACLKYLDLGHQLHSVIIKNKFASNLFVGNALVDMYAKSGALEDARQQFELIRNRDNVSWNVIIVGYVQEEDEVEAFHLFRRMNLLGILPDEVSLASILSACASVRGLEQGKQVHCLSVKTGQETKLYSGSSLIDMYAKCGAIDSAHKILACMPERSVVSMNALIAGYAQINLE-QAVNLFRDMLVEGINSTEITFASLLDACHEQQKLNLGRQIHCLILKMGLQLDDEFLGVSLLGMYMNSLRTTDASVLFSEFSNPKSAVV-WTAMISGLSQNDCSVVALQLYKEMRSCNVLPDQATFVSALRACAVVSSIKDGTETHSLIFHTGFDSDELTSSALVDMYAKCGDVKSSMQVFKEMSRKKDVISWNSMIVGFAKNGYAEDALRVFDEMKQSHVTPDDVTFLGVLTACSHSGRVSEGRLIFDMMVNLYGMQPRADHCACMVDLLGRWGSLKEAEEFINKLN-FEPDAKVWATMLGACRIHGDDIRGQQAAEKLIELEPQNSSPYVLLSNIYAASGNWDEVNTLRREMREKGVKKLPGCSWIVVGQETNMFVAGDKSH 992          

Query:   25 KLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIAR-LLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLR 1893
            K+IH + L LG  +   L   +++ Y  C   D A+  F+ +E+   I  WN +++  +K   F   +  +  LL    + P+ +T+  VL +C  L  V  G+ +H +++K GF S      +L+ MYAKCN    A  +FD   E D   W ++I  Y + G  ++A+++F++M   G  P+ V   TVI+                               A VD+    G LD A ++F ++P +NVVAWN MI+ ++  G  +  I+FF+ M + G   T +T  S+L A +  A L  G  +HA  ++  + +++Y+ SSL+ +Y   G + +AK VF+ + + N V WN M+ GYV+ G     + ++ +MK  G  P+  T +SILSAC+ L  L+ G ++H  +I ++F +N  +  AL+DMYAK GA+++A   F  + NRD VSW  +I  Y      +EA  LF  M      PD V+L ++LSAC+ V  +++G    + +    G + ++   S LID+  + G ++ A++IL    E R  V + + +    ++  NL+  V + R +L+E       T+  L +     +K +  +++   + ++GL+
Sbjct:   79 KIIHAQSLKLGFWSKGVLGNVIVDLYAKCADVDYAERAFKQLED-KDILAWNSILSMHSKQG-FPHLVVKYFGLLWNSGVWPNEFTFAIVLSSCARLEMVKCGRQVHCNVVKMGFESISYCEGALIGMYAKCNFLTDARSIFDGAVELDKVSWTSMIGGYIKVGLPEEAVKVFQEMEKVGQEPDQVAFVTVIN-------------------------------AYVDL----GRLDNASDLFSRMPNRNVVAWNLMISGHAKGGYGVEAIEFFQNMRKAGIKSTRSTLGSVLSAIASLAALDFGLLVHAEALKQGLHSNVYVGSSLVSMYAKCGKMEAAKKVFDTLNEQNVVLWNAMLGGYVQNGYANEVMELFFNMKSCGFYPDDFTYSSILSACACLKYLDLGHQLHSVIIKNKFASNLFVGNALVDMYAKSGALEDARQQFELIRNRDNVSWNVIIVGYVQEEDEVEAFHLFRRMNLLGILPDEVSLASILSACASVRGLEQGKQ-VHCLSVKTGQETKLYSGSSLIDMYAKCGAIDSAHKILACMPE-RSVVSMNALIAGYAQI--NLEQAVNLFRDMLVEGINSTEITFASLLDACHEQQKLNLGRQIHCLILKMGLQ 661          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSAC 1518
            +K G+ +H  ++ +G ++       LI  Y  C+F   A+ +F        +S W  ++ G+ K  +  EA+++F+ + +     PD   + +V+ A   LG++                                   D A  LF  MP R+V  WN +IS + + G   +A+E F+ MR +G      TL +V+S+ A L  L+ G+ +H E +K  L  + +V S+LV MY KCG ++ AK+VF+ +  +NVV WN+M+  Y   G +   ++ F  M   G  P   T+SSIL AC+    L  G  +H+ +I+N   +++++ ++L+D+Y  SG++  A+  FE +   + VSWNV+I GYV+  D   A  ++  M   G+ P+ +++ SILSAC+ +  LE+GK++H   + +  ET      +L+DMYAKCGA+D A  +   +P R  VS  ++I  Y       +A+ LF +M         +T  ++L AC
Sbjct:  176 VKCGRQVHCNVVKMGFESISYCEGALIGMYAKCNFLTDARSIFDGAVELDKVS-WTSMIGGYIKVGLPEEAVKVFQEMEKVGQ-EPDQVAFVTVINAYVDLGRL-----------------------------------DNASDLFSRMPNRNVVAWNLMISGHAKGGYGVEAIEFFQNMRKAGIKSTRSTLGSVLSAIASLAALDFGLLVHAEALKQGLHSNVYVGSSLVSMYAKCGKMEAAKKVFDTLNEQNVVLWNAMLGGYVQNGYANEVMELFFNMKSCGFYPDDFTYSSILSACACLKYLDLGHQLHSVIIKNKFASNLFVGNALVDMYAKSGALEDARQQFELIRNRDNVSWNVIIVGYVQEEDEVEAFHLFRRMNLLGILPDEVSLASILSACASVRGLEQGKQVHCLSVKTGQETKLYSGSSLIDMYAKCGAIDSAHKILACMPERSVVSMNALIAGYAQINLE-QAVNLFRDMLVEGINSTEITFASLLDAC 639          

Query:    7 NSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERD-VACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIK 663
            +S+K G   H  +   G  +D      L++ Y  C    S+  VF+ +     +  WN ++ GF KN    +AL +F+  ++  ++ PD  T+  VL AC   G+V  G++I                            FD  + L+   P  D  AC   ++  +   G  ++A E   K+    F P++    T++ +C    D  RG +  ++LI+
Sbjct:  746 SSIKDGTETHSLIFHTGFDSDELTSSALVDMYAKCGDVKSSMQVFKEMSRKKDVISWNSMIVGFAKNGYAEDALRVFDE-MKQSHVTPDDVTFLGVLTACSHSGRVSEGRLI----------------------------FDMMVNLYGMQPRADHCACMVDLLGRW---GSLKEAEEFINKL---NFEPDAKVWATMLGACRIHGDDIRGQQAAEKLIE 930          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPY-IGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            N     GK +H +++  G   D      L+NFY        A  +F  + + +++S    ++ G+++   F EA+ LF  L    + + P  + + +VLK   +      G  +H  + K GF SD  V ++L+  Y+ C   +CA ++FD +  +D+  W  +++CY ++   +++++LF +MR  GF PN+ T  +V+ +C  L     G  +H    K   + + FV   L+D+Y K G +D A +VFE++P  +V+ W+ MIA Y+ +  S   I+ F RM R    P   T +S+L AC+    L  G  IH  +++  ++ ++++ ++L+D+Y   G + ++  +F + P    VSWN +I GYV+ G+   AL ++ DM E  V+   +T +S+L AC+ +AALE G +IH   + + ++ N ++  AL+DMYAKCG + +A  VF+ L   D VSW +MI+ Y  HG   EALK F  M ++  KPD VT + +LSACS+ GL+D G  +F  M+  Y I+P  EHY+C++ LLGR+G L++A +++         V +   L SAC +H +++LG   A+ ++E  P+D +T+++LSN YA+ ++W  V  +R  MK  G+RK PG SWIE   ++H F VGD SHP +++
Sbjct:   57 NGDCATGKYLHCEIIKKGNCLDLFANNILLNFYVKYDSLPDAAKLFDEMPDRNTVSFVT-LIQGYSQCLRFSEAIGLFSRLQGEGHELNP--FVFSTVLKLLVSAEWAKLGFSVHACVYKLGFDSDAFVGTALIDCYSVCGYAECARQVFDAIEYKDMVSWTGMVACYVENECFEESLKLFSRMRIVGFKPNNFTFASVLKACVGLEVFNVGKAVHGCAFKTSYLEELFVGVELIDLYIKSGDVDDALQVFEEMPKDDVIPWSFMIARYAQSEQSEEAIEMFCRMRRGLVLPNQFTLASLLQACASLVDLQLGNQIHCHVVKVGLDMNVFVSNALMDMYAKCGRMENSLQLFSESPNCTDVSWNTVIVGYVQAGNGEKALILFKDMLECQVQGTEVTYSSVLRACAGIAALEPGSQIHSLSVKTIYDKNTVVGNALIDMYAKCGNIKDARLVFDMLREHDQVSWNAMISGYSVHGLYGEALKTFESMLETECKPDKVTFVGILSACSNAGLLDRGQAYFKSMVEEYDIEPCAEHYTCMVWLLGRSGHLDKAAKLVHEI-PFEPSVMVWRALLSACVIHNDVELGRISAQRVLEIEPEDEATHVLLSNIYANARRWGNVASIRTSMKRKGIRKEPGLSWIENQGRVHYFSVGDTSHPDTKL 712          

Query:  271 DSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEA 1653
            ++Y Y S+L++C   G    GK +H  +IK G   D+   + L+  Y K +    A +LFDEMP+R+   + T+I  Y Q  +  +A+ LF +++  G   N    +TV+         + G  +H  + K     D+FV +AL+D Y  CG  + A++VF+ I  K++V+W  M+A Y         ++ F RM   G  P   TF+S+L AC        GK +H    +     ++++   LIDLY  SG V  A  VFE+MPK + + W+ MI+ Y +      A+ ++  M+   V PN  T+ S+L AC+ L  L+ G +IH  V+    + N  +  AL+DMYAKCG ++ +L +F+  PN   VSW ++I  Y   G   +AL LF +M +   +   VT  +VL AC+ +  ++ G    +  +     K  +   + LID+  + G + +A
Sbjct:   43 NTYIYGSLLQSCIRNGDCATGKYLHCEIIKKGNCLDLFANNILLNFYVKYDSLPDAAKLFDEMPDRNTVSFVTLIQGYSQCLRFSEAIGLFSRLQGEGHELNPFVFSTVLKLLVSAEWAKLGFSVHACVYKLGFDSDAFVGTALIDCYSVCGYAECARQVFDAIEYKDMVSWTGMVACYVENECFEESLKLFSRMRIVGFKPNNFTFASVLKACVGLEVFNVGKAVHGCAFKTSYLEELFVGVELIDLYIKSGDVDDALQVFEEMPKDDVIPWSFMIARYAQSEQSEEAIEMFCRMRRGLVLPNQFTLASLLQACASLVDLQLGNQIHCHVVKVGLDMNVFVSNALMDMYAKCGRMENSLQLFSESPNCTDVSWNTVIVGYVQAGNGEKALILFKDMLECQVQGTEVTYSSVLRACAGIAALEPGSQIHSLSVKTIYDKNTVVG-NALIDMYAKCGNIKDA 502          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            LKQGKL+HQK+LTLGLQND ALCKNLI+FYFSCHF DSAKLVFQSIENPSSISLWNG+MT +TKN MF EALELF SLLRYPY+ PDSYTYPSVLK CGALG+V  GKMIHNHLIK GFVSDIVVASSLVCMYAKCN+F+CAI+LFDEMPERDVACWNTVISCYYQDGQA+KA++L+EKMRNSGF PNSVTLTTVISSCAR+ DLERGM+IHKELIK +LVLDSFV SALVDMYGKCGCLDMAK+VFEQIPIKNV++WNSMI AYSV+GDS SCIQ FRRMN EGTSPTLTTFSSILLACSRSAQL HGKFIHAF+IRNIIEADIYIYSSL+DLYF  GSVSSAK VFEKMPKTN  SWNVMISGYVKVGDYFGALA+YDDMK AGVRPNAITVTSILSACSQLAALEKGKEIHRT+IDSE ETNEI+MGALLDMYAKCG VDEAL VFNRLP+RD VSWTSMITAYG+HGQALEALKLFGEMQQS AKPDGVTLLAVLSACSHVGLVDEGCH+F+QMIT+YGIKPR+EHYSCL+DLLGRAGRL+ AY+ILQRT EIREDVDLLSTLFSAC LH++LDLGVKIA LL+EKNPDD STYIMLSN YASVKKWDEV+KVRLKMKELGLRK PGCSWIEINK+I PFFV DKSH QSEM
Sbjct:   19 LKQGKLVHQKILTLGLQNDLALCKNLIDFYFSCHFXDSAKLVFQSIENPSSISLWNGLMTAYTKNFMFNEALELFGSLLRYPYLCPDSYTYPSVLKGCGALGEVSLGKMIHNHLIKIGFVSDIVVASSLVCMYAKCNIFECAIQLFDEMPERDVACWNTVISCYYQDGQARKAIDLYEKMRNSGFMPNSVTLTTVISSCARISDLERGMEIHKELIKSRLVLDSFVCSALVDMYGKCGCLDMAKQVFEQIPIKNVISWNSMITAYSVSGDSRSCIQLFRRMNDEGTSPTLTTFSSILLACSRSAQLQHGKFIHAFIIRNIIEADIYIYSSLLDLYFKCGSVSSAKIVFEKMPKTNAASWNVMISGYVKVGDYFGALAMYDDMKVAGVRPNAITVTSILSACSQLAALEKGKEIHRTLIDSELETNEIVMGALLDMYAKCGVVDEALYVFNRLPDRDLVSWTSMITAYGAHGQALEALKLFGEMQQSYAKPDGVTLLAVLSACSHVGLVDEGCHYFSQMITDYGIKPRVEHYSCLMDLLGRAGRLDGAYQILQRTPEIREDVDLLSTLFSACCLHKDLDLGVKIAGLLMEKNPDDPSTYIMLSNIYASVKKWDEVRKVRLKMKELGLRKYPGCSWIEINKRIQPFFVEDKSHSQSEM 674          

Query:    7 NSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNI-IEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPK 1071
            + L++G  IH++++   L  D  +C  L++ Y  C   D AK VF+ I   + IS WN ++T ++ +      ++LF   +      P   T+ S+L AC    Q+  GK IH  +I+    +DI + SSL+ +Y KC     A  +F++MP+ + A WN +IS Y + G    A+ +++ M+ +G  PN++T+T+++S+C++L  LE+G +IH+ LI  +L  +  V  AL+DMY KCG +D A  VF ++P +++V+W SMI AY   G ++  ++ F  M +    P   T  ++L ACS    +  G    + MI +  I+  +  YS L+DL   +G +  A  + ++ P+
Sbjct:  221 SDLERGMEIHKELIKSRLVLDSFVCSALVDMYGKCGCLDMAKQVFEQIPIKNVIS-WNSMITAYSVSGDSRSCIQLFRR-MNDEGTSPTLTTFSSILLACSRSAQLQHGKFIHAFIIRNIIEADIYIYSSLLDLYFKCGSVSSAKIVFEKMPKTNAASWNVMISGYVKVGDYFGALAMYDDMKVAGVRPNAITVTSILSACSQLAALEKGKEIHRTLIDSELETNEIVMGALLDMYAKCGVVDEALYVFNRLPDRDLVSWTSMITAYGAHGQALEALKLFGEMQQSYAKPDGVTLLAVLSACSHVGLVDEGCHYFSQMITDYGIKPRVEHYSCLMDLLGRAGRLDGAYQILQRTPE 574          

Query:  574 NSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVA-WNSMIAAYSVTGDSISCIQFFRRMNR-EGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            ++  L  ++  C     L++G  +H++++   L  D  +   L+D Y  C   D AK VF+ I   + ++ WN ++ AY+        ++ F  + R     P   T+ S+L  C    ++  GK IH  +I+    +DI + SSL+ +Y        A  +F++MP+ +   WN +IS Y + G    A+ +Y+ M+ +G  PN++T+T+++S+C++++ LE+G EIH+ +I S    +  +  AL+DMY KCG +D A  VF ++P ++ +SW SMITAY   G +   ++LF  M      P   T  ++L ACS    +  G  F +  I    I+  I  YS L+DL  + G ++ A  + ++
Sbjct:    2 DTTKLLCLLRMCISSKLLKQGKLVHQKILTLGLQNDLALCKNLIDFYFSCHFXDSAKLVFQSIENPSSISLWNGLMTAYTKNFMFNEALELFGSLLRYPYLCPDSYTYPSVLKGCGALGEVSLGKMIHNHLIKIGFVSDIVVASSLVCMYAKCNIFECAIQLFDEMPERDVACWNTVISCYYQDGQARKAIDLYEKMRNSGFMPNSVTLTTVISSCARISDLERGMEIHKELIKSRLVLDSFVCSALVDMYGKCGCLDMAKQVFEQIPIKNVISWNSMITAYSVSGDSRSCIQLFRRMNDEGTSPTLTTFSSILLACSRSAQLQHG-KFIHAFIIRNIIEADIYIYSSLLDLYFKCGSVSSAKIVFEK 368          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            SL+ GK +H  +   G++ D  L   L+  Y  C     A+ VF  + N   + +WN ++  + K   F E + LF  +     I  +SYT+  VLK   ALG V  G+ IH +L K GF SD  V +SL+  Y K    + A ++FDE+ +RDV  WN++IS Y  +G A+K +E+F +M + G   +  T+  V+ +C    +L  G  +H   IK     D    + ++DMY KCG L  A +VF+++  ++VV+W SMIA +   G S   I  F  M R+G +P   T +SIL AC+ S  L  G+ IH ++  + +++ +Y+ ++L+D+Y   GS+  A +VF +MP  + VSWN MI GY K      AL ++ +M +   +P+++T+ S+L AC+ LAAL +G+EIH  ++ + + +   +  AL+DMY KCG +  A  +F+ +P +D +SWT +   YG HG   EA+  F EM+++  +PD V+ +++L ACSH GL DE   FF+ M  +YGI P++EHY+C++DLL R G L +AY+ + +T  I  D  +  +L   CR+H ++ L  K+A  + E  P++   Y++L+N YA  +KW+EVK +R ++   GL+KNPGCSWIEI  K+  F  GD SHPQ+
Sbjct:  559 SLQDGKXVHSVICDNGVEADGQLGAKLVFMYVKCGDLREARRVFDKLSN-GKVFVWNLMINEYAKVRNFREGVYLFGKMQELG-IQANSYTFSCVLKCFSALGCVREGEWIHGYLYKLGFGSDNTVGNSLMAFYFKNRRIEXARKVFDELCDRDVISWNSMISAYVSNGLAEKGVEIFRQMVSLGIDVDLATIINVLMACVAGGNLSLGRALHAYAIKASFDEDVMFCNNVLDMYSKCGDLSSAIQVFKKMGERSVVSWTSMIAGHIREGLSDEAIGLFSEMERDGVNPDAYTITSILHACASSGSLKKGRDIHNYIKEHGMDSSLYVCNTLMDMYAKCGSMEDAHSVFSRMPAKDIVSWNTMIGGYSKNCLPNEALKLFSEMMQKS-KPDSMTIASVLPACASLAALNRGQEIHGHILRNGYFSERHVANALVDMYVKCGVLVLARLLFDXIPVKDLISWTVIXAGYGMHGFGREAIAAFNEMRKAGIEPDSVSFISILYACSHSGLXDEAWRFFDTMRNDYGIVPKLEHYACMVDLLSRTGNLTKAYKFI-KTMPIEPDATIWGSLLCGCRIHHDVKLAEKVAEHVFELEPENTGYYVLLANIYAEAEKWEEVKMLRERITRRGLKKNPGCSWIEIKGKVKIFVAGDSSHPQA 1209          

Query:  271 DSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRL 1644
            D   Y SV++ C  +  +  GK +H+ +   G  +D  + + LV MY KC     A R+FD++    V  WN +I+ Y +    ++ + LF KM+  G   NS T + V+   + L  +  G  IH  L K     D+ V ++L+  Y K   ++ A++VF+++  ++V++WNSMI+AY   G +   ++ FR+M   G    L T  ++L+AC     L  G+ +HA+ I+   + D+   ++++D+Y   G +SSA  VF+KM + + VSW  MI+G+++ G    A+ ++ +M+  GV P+A T+TSIL AC+   +L+KG++IH  + +   +++  +   L+DMYAKCG++++A +VF+R+P +D VSW +MI  Y  +    EALKLF EM Q  +KPD +T+ +VL AC+ +  ++ G      ++ N G        + L+D+  + G L
Sbjct:  543 DLEAYCSVVELCAGMMSLQDGKXVHSVICDNGVEADGQLGAKLVFMYVKCGDLREARRVFDKLSNGKVFVWNLMINEYAKVRNFREGVYLFGKMQELGIQANSYTFSCVLKCFSALGCVREGEWIHGYLYKLGFGSDNTVGNSLMAFYFKNRRIEXARKVFDELCDRDVISWNSMISAYVSNGLAEKGVEIFRQMVSLGIDVDLATIINVLMACVAGGNLSLGRALHAYAIKASFDEDVMFCNNVLDMYSKCGDLSSAIQVFKKMGERSVVSWTSMIAGHIREGLSDEAIGLFSEMERDGVNPDAYTITSILHACASSGSLKKGRDIHNYIKEHGMDSSLYVCNTLMDMYAKCGSMEDAHSVFSRMPAKDIVSWNTMIGGYSKNCLPNEALKLFSEMMQ-KSKPDSMTIASVLPACASLAALNRGQEIHGHILRN-GYFSERHVANALVDMYVKCGVL 998          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSA-LVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGD 822
            + SLK+G+ IH  +   G+ +   +C  L++ Y  C   + A  VF  +     +S WN ++ G++KN +  EAL+LF  +++     PDS T  SVL AC +L  +  G+ IH H+++ G+ S+  VA++LV MY KC V   A  LFD +P +D+  W  + + Y   G  ++A+  F +MR +G  P+SV+  +++ +C+     +   +    +  D  ++      A +VD+  + G L  A +  + +PI+ +   W S++    +  D
Sbjct:  860 SGSLKKGRDIHNYIKEHGMDSSLYVCNTLMDMYAKCGSMEDAHSVFSRMPAKDIVS-WNTMIGGYSKNCLPNEALKLFSEMMQKS--KPDSMTIASVLPACASLAALNRGQEIHGHILRNGYFSERHVANALVDMYVKCGVLVLARLLFDXIPVKDLISWTVIXAGYGMHGFGREAIAAFNEMRKAGIEPDSVSFISILYACSHSGLXDEAWRFFDTMRNDYGIVPKLEHYACMVDLLSRTGNLTKAYKFIKTMPIEPDATIWGSLLCGCRIHHD 1131          

Query:    4 NNSLKQGKLIHQKML--TLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMN-REGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            + SL QGK IHQ +L  T  L++   L + + + Y +C+    A  VF  I  PS I LWN ++ G+  N  F +A++L+  +L+   + P +YTYP VLKAC  L  +  G+ IH H    G  SD+ V ++L+ +YAKC     A  +F  M  +D+  WN +I  +   G     ++L  +M+ +G +PNS T+ +V+ + A+   L +G  +H   ++     +  + + L+DMY K  C+  A+ +F+ +  KN V W++MI AY +       I  F  M  RE  +PT  T  SIL AC++   L  G+ +H + I+   + D  + ++++ +Y   G +  A   F+ M   +TVS+  +ISGYV+ G    AL ++ +M+ +G+ P+  T+  +L ACS LAAL+ G   H   I   F T+  +  AL+DMY+KCG ++    VF+++  RD +SW +MI  YG+HG  +EA+  F  MQ S  KPD VT + +LSACSH GLV EG H+F++M   + I PR+EHY C++D+L RAG L+EA+  +QR      DV + S L +ACR+H N++LG ++++ +  K  +     ++LSN Y++V +WD+   VR+K K+ GL+K+PGCSW+EI+  IH F  GD+SHPQS
Sbjct:  191 SKSLPQGKKIHQLLLKNTTHLKDSSFLLEKVAHLYITCNQLQLACRVFDKIPQPSVI-LWNLLIRGYAWNGPFEKAIDLYYGMLKSG-VQPTNYTYPFVLKACSGLQALEVGREIHEHARGLGLHSDVYVCTALIDLYAKCGDLVEAQSVFHGMLYKDIVAWNAMIXGFSLHGLYDDTVQLLVQMQRAGTSPNSSTIVSVLPTVAQANALRQGKAMHGYSLRRGFSGEVVLGTGLLDMYSKSQCIAYARRIFDAMNFKNEVCWSAMIGAYVICDSMTEAITLFHEMVIREEINPTAVTLGSILRACAKLTDLSRGRRVHCYAIKAGFDLDKMVGNTMLSVYAKCGIIDDAVRFFDTMNSKDTVSYGAIISGYVQNGYAKEALLMFHNMQLSGINPDVATMKGVLPACSHLAALQHGACGHAYSIVHGFCTDTSICNALIDMYSKCGKINIGRKVFDKMVTRDIISWNAMIVGYGNHGLGMEAISQFHHMQSSGIKPDDVTFIGLLSACSHSGLVTEGKHWFSKMSQEFNINPRMEHYICMVDILARAGHLDEAHSFIQR-MPFEADVRVWSALLAACRVHNNMELGEEVSKKIQGKGLEGTGNLVLLSNLYSAVGRWDDAADVRIKQKDQGLKKSPGCSWVEIDGVIHGFVGGDQSHPQS 847          

Query:  277 YTYPSVLKACGALGQVGFGKMIHNHLIK--TGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMK-EAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGC--HFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            + Y  +L+AC     +  GK IH  L+K  T       +   +  +Y  CN    A R+FD++P+  V  WN +I  Y  +G  +KA++L+  M  SG  P + T   V+ +C+ L  LE G +IH+      L  D +V +AL+D+Y KCG L  A+ VF  +  K++VAWN+MI  +S+ G     +Q   +M R GTSP  +T  S+L   +++  L  GK +H + +R     ++ + + L+D+Y  S  ++ A+ +F+ M   N V W+ MI  YV       A+ ++ +M     + P A+T+ SIL AC++L  L +G+ +H   I + F+ ++++   +L +YAKCG +D+A+  F+ + ++D VS+ ++I+ Y  +G A EAL +F  MQ S   PD  T+  VL ACSH+  +  G   H ++ +   +G        + LID+  + G++N   ++  +
Sbjct:  179 FDYKHLLEACIRSKSLPQGKKIHQLLLKNTTHLKDSSFLLEKVAHLYITCNQLQLACRVFDKIPQPSVILWNLLIRGYAWNGPFEKAIDLYYGMLKSGVQPTNYTYPFVLKACSGLQALEVGREIHEHARGLGLHSDVYVCTALIDLYAKCGDLVEAQSVFHGMLYKDIVAWNAMIXGFSLHGLYDDTVQLLVQMQRAGTSPNSSTIVSVLPTVAQANALRQGKAMHGYSLRRGFSGEVVLGTGLLDMYSKSQCIAYARRIFDAMNFKNEVCWSAMIGAYVICDSMTEAITLFHEMVIREEINPTAVTLGSILRACAKLTDLSRGRRVHCYAIKAGFDLDKMVGNTMLSVYAKCGIIDDAVRFFDTMNSKDTVSYGAIISGYVQNGYAKEALLMFHNMQLSGINPDVATMKGVLPACSHLAALQHGACGHAYSIV---HGFCTDTSICNALIDMYSKCGKINIGRKVFDK 645          

Query:  499 CYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVL--DSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQ-QSNAKPDGVTLLAVLSACSHVGLVDEG 1545
            CY+   QA   + L      +  T        ++ +C R   L +G KIH+ L+K+   L   SF+   +  +Y  C  L +A  VF++IP  +V+ WN +I  Y+  G     I  +  M + G  PT  T+  +L ACS    L  G+ IH       + +D+Y+ ++LIDLY   G +  A++VF  M   + V+WN MI G+   G Y   + +   M+ AG  PN+ T+ S+L   +Q  AL +GK +H   +   F    ++   LLDMY+K   +  A  +F+ +  ++ V W++MI AY       EA+ LF EM  +    P  VTL ++L AC+ +  +  G
Sbjct:  154 CYHTTQQA--VVILTHNFSTNTLTRLDFDYKHLLEACIRSKSLPQGKKIHQLLLKNTTHLKDSSFLLEKVAHLYITCNQLQLACRVFDKIPQPSVILWNLLIRGYAWNGPFEKAIDLYYGMLKSGVQPTNYTYPFVLKACSGLQALEVGREIHEHARGLGLHSDVYVCTALIDLYAKCGDLVEAQSVFHGMLYKDIVAWNAMIXGFSLHGLYDDTVQLLVQMQRAGTSPNSSTIVSVLPTVAQANALRQGKAMHGYSLRRGFSGEVVLGTGLLDMYSKSQCIAYARRIFDAMNFKNEVCWSAMIGAYVICDSMTEAITLFHEMVIREEINPTAVTLGSILRACAKLTDLSRG 503          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSP---TLTTFSSILLACSRSAQLLHGKFIHAFMIRN--IIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAG-VRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            ++   K +H  ++ LG   +  L   L+N Y        ++  F SI     +  WN +++ + ++  F EAL+ F        + PD YT+P VLKAC  L     GK IH  ++K GF  D+ VA+SL+ MY++      A +LFD+MP RD   WN +IS + Q+  A  A+++  +MR  G   + VT+ +++++CA+  D+  G  IH  +IK  L  D FV +AL++MY K G L  A+ VF+Q+ ++++V+WNS++AAY    D I+ ++ F  M   G  P   TL + +SIL   S S +    K +H F++R    +E D+ I ++++D+Y   G++ SA+ VFE +P  + VSWN +I+GY + G    A+ +Y  M++   + PN  T  SIL A + + AL++G ++H  VI +   ++  +   L+DMY KCG +D+AL +F+++P +  V W ++I+ +G HG   +AL+LF +M     KPD VT +++++ACSH GLV+EG  FF+ M   YGIKP ++HY C++DLLGRAG LN+AY  ++  S +R D  +   L  ACR+H N+++G   +  L E + ++   Y++LSN YA+  KW+ V+KVR   +  GL K PG S IE+N  +  F+  ++SHP+ E
Sbjct:   82 NVHHAKQLHAYLVVLGKSQNIFLAAKLVNRYAYLGDLSFSRRTFDSIPR-KDVYTWNSMVSAYVRSGRFREALDCFSQFSLTSDLHPDFYTFPPVLKACENLVD---GKKIHCRVLKLGFEWDVFVAASLIHMYSRFGFIYVARKLFDDMPIRDTGSWNAMISGFCQNANAADALDVLVEMRMEGIKMDRVTVASLLTACAQSNDISSGRLIHLYVIKHGLDFDLFVCNALINMYSKFGSLGHARRVFDQMEVRDLVSWNSIVAAYEQNNDPITALELFNAMQLRGIQPDFLTLVSLASILAQLSDSEK---SKSVHGFILRRDWFVE-DVVIGNAVVDMYAKLGAIDSARTVFEGLPTKDAVSWNTLITGYAQNGHASEAIEVYRMMQQCKEIIPNHGTWVSILPAYTHVGALQQGMKVHGRVIKNRVYSDVFVGTCLIDMYGKCGRLDDALCLFSQVPRKSSVPWNALISCHGVHGHGEKALQLFNDMLDEGVKPDHVTFVSLMAACSHSGLVNEGQSFFHTMQEQYGIKPSLKHYGCMVDLLGRAGHLNKAYSFIENMS-VRPDASVWGALLGACRIHGNVEMGKIASERLFEVDSENVGYYVLLSNIYANFGKWEGVEKVRSLARNRGLTKTPGWSSIEVNNNVDVFYTANQSHPKCE 734          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTG-FVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRN-SGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGK-FIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMP-KTNTVSWNVM-----ISGYVKVG 1122
            +N +  G+LIH  ++  GL  D  +C  LIN Y        A+ VF  +E    +S WN ++  + +N+  + ALELF + ++   I PD  T  S+      L      K +H  +++   FV D+V+ +++V MYAK    D A  +F+ +P +D   WNT+I+ Y Q+G A +A+E++  M+      PN  T  +++ +   +  L++GMK+H  +IK+++  D FV + L+DMYGKCG LD A  +F Q+P K+ V WN++I+ + V G     +Q F  M  EG  P   TF S++ ACS S  +  G+ F H    +  I+  +  Y  ++DL   +G ++ A +  E M  + +   W  +     I G V++G
Sbjct:  280 SNDISSGRLIHLYVIKHGLDFDLFVCNALINMYSKFGSLGHARRVFDQMEVRDLVS-WNSIVAAYEQNNDPITALELFNA-MQLRGIQPDFLTLVSLASILAQLSDSEKSKSVHGFILRRDWFVEDVVIGNAVVDMYAKLGAIDSARTVFEGLPTKDAVSWNTLITGYAQNGHASEAIEVYRMMQQCKEIIPNHGTWVSILPAYTHVGALQQGMKVHGRVIKNRVYSDVFVGTCLIDMYGKCGRLDDALCLFSQVPRKSSVPWNALISCHGVHGHGEKALQLFNDMLDEGVKPDHVTFVSLMAACSHSGLVNEGQSFFHTMQEQYGIKPSLKHYGCMVDLLGRAGHLNKAYSFIENMSVRPDASVWGALLGACRIHGNVEMG 659          

Query:   25 KLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFV-SDIVVASSLVCMYAKCNV-FDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKC---GCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSIS-CIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            KL+H ++    L+ D  L  +LI+ Y        A  +F+++ +  ++  W+ +++ F  N M  EA+  F  +L + +  P+ Y + SV++AC     +G GK+I   +IK G++ SD+ V  SL+ M+AK       A ++F+EMPE D   W  +I+ + Q G  ++A+ L+  M  SGF P+   L+ VIS+C +L  L  G ++H  +I+  L L   V   LVDMY KC   G ++ A++VF+++P  NV++W ++I  Y  +G      I+ F  M      P   TFSSIL AC+  + L  G+ IH+  +++ + +   + +SLI +Y  SG V  A+  F+ + + N +S+N ++  Y K  D   A  ++ ++++ G   +A T +S+LS  + + A  KG++IH  +I S  E+N+I+   L+ MY++CG +D A  VFN + + + +SWTSMIT +  HG A  A+++F +M ++  KP+ +T +AVLSACSH GLVDEG   F +M   +G+ PR+EHY+C++DLLGR+G L EA E +  +     D  +  T   ACR+H N++LG   A+++IE+NP D + Y +LSN YAS  +W+EV KVR  MKE  L K  G SWIE+  KIH F VGD SHP+++
Sbjct:   82 KLVHDRLAHSQLEPDQVLLNSLISLYSKSGDWKKANSIFENMGSERNLVSWSAMVSCFANNDMGFEAISTFLDMLEHGFY-PNEYCFASVIRACSNARNIGIGKVIFGSVIKGGYLGSDVCVGCSLIDMFAKGGGDLGEAYKVFEEMPETDAVTWTLMITRFAQMGFPREAIGLYVDMLLSGFMPDQFALSGVISACTKLESLSLGQQLHSWVIRSGLALGHCVGCCLVDMYAKCAADGSMNDARKVFDRMPNHNVMSWTAIINGYVQSGKGDEEAIKLFVEMMSGHVPPNHFTFSSILKACANLSDLCKGEQIHSLAVKSGLASVNCVGNSLITMYSKSGQVEDARKSFDVLYEKNLISYNTIVDAYAKHLDAEEAFGLFHEIQDTGYGASAFTFSSLLSGAASICAAGKGEQIHARIIKSGLESNQIICNXLVSMYSRCGNIDAAFLVFNEMEDWNVISWTSMITGFAKHGYAAAAVEMFNKMLEAGIKPNXITYIAVLSACSHAGLVDEGWKHFKEMQKKHGVVPRMEHYACMVDLLGRSGSLVEALEFI-NSMPFTADELIWRTFLGACRVHGNIELGKHAAKMIIEQNPRDSAAYSLLSNLYASTGRWEEVAKVRKYMKEKYLIKEVGSSWIEVKNKIHKFHVGDTSHPKAK 736          

Query:  244 LLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEM-PERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIK-DQLVLDSFVTSALVDMYGK-CGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLY---FVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVG-DYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSE 1680
            LL    I PD  TY  ++K+C         K++H+ L  +    D V+ +SL+ +Y+K   +  A  +F+ M  ER++  W+ ++SC+  +    +A+  F  M   GF PN     +VI +C+   ++  G  I   +IK   L  D  V  +L+DM+ K  G L  A +VFE++P  + V W  MI  ++  G     I  +  M   G  P     S ++ AC++   L  G+ +H+++IR+ +     +   L+D+Y      GS++ A+ VF++MP  N +SW  +I+GYV+ G     A+ ++ +M    V PN  T +SIL AC+ L+ L KG++IH   + S   +   +  +L+ MY+K G V++A   F+ L  ++ +S+ +++ AY  H  A EA  LF E+Q +       T  ++LS  + +    +G     ++I + G++      + L+ +  R G ++ A+ +     +
Sbjct:   52 LLAQRGIHPDLPTYSLLIKSCIRSRNFDLXKLVHDRLAHSQLEPDQVLLNSLISLYSKSGDWKKANSIFENMGSERNLVSWSAMVSCFANNDMGFEAISTFLDMLEHGFYPNEYCFASVIRACSNARNIGIGKVIFGSVIKGGYLGSDVCVGCSLIDMFAKGGGDLGEAYKVFEEMPETDAVTWTLMITRFAQMGFPREAIGLYVDMLLSGFMPDQFALSGVISACTKLESLSLGQQLHSWVIRSGLALGHCVGCCLVDMYAKCAADGSMNDARKVFDRMPNHNVMSWTAIINGYVQSGKGDEEAIKLFVEMMSGHVPPNHFTFSSILKACANLSDLCKGEQIHSLAVKSGLASVNCVGNSLITMYSKSGQVEDARKSFDVLYEKNLISYNTIVDAYAKHLDAEEAFGLFHEIQDTGYGASAFTFSSLLSGAASICAAGKGEQIHARIIKS-GLESNQIICNXLVSMYSRCGNIDAAFLVFNEMED 536          

Query:  514 GQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQI-PIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIR-NIIEADIYIYSSLIDLYFV-SGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKC---GAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQA-LEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSC----LIDLLGRAGRLNEA 1653
            G  +KA+   + +   G  P+  T + +I SC R  + +    +H  L   QL  D  + ++L+ +Y K G    A  +FE +   +N+V+W++M++ ++        I  F  M   G  P    F+S++ ACS +  +  GK I   +I+   + +D+ +  SLID++    G +  A  VFE+MP+T+ V+W +MI+ + ++G    A+ +Y DM  +G  P+   ++ ++SAC++L +L  G+++H  VI S       +   L+DMYAKC   G++++A  VF+R+PN + +SWT++I  Y   G+   EA+KLF EM   +  P+  T  ++L AC+++  + +G     + I +  +K  +   +C    LI +  ++G++ +A
Sbjct:   41 GHLRKAITTLDLLAQRGIHPDLPTYSLLIKSCIRSRNFDLXKLVHDRLAHSQLEPDQVLLNSLISLYSKSGDWKKANSIFENMGSERNLVSWSAMVSCFANNDMGFEAISTFLDMLEHGFYPNEYCFASVIRACSNARNIGIGKVIFGSVIKGGYLGSDVCVGCSLIDMFAKGGGDLGEAYKVFEEMPETDAVTWTLMITRFAQMGFPREAIGLYVDMLLSGFMPDQFALSGVISACTKLESLSLGQQLHSWVIRSGLALGHCVGCCLVDMYAKCAADGSMNDARKVFDRMPNHNVMSWTAIINGYVQSGKGDEEAIKLFVEMMSGHVPPNHFTFSSILKACANLSDLCKG-----EQIHSLAVKSGLASVNCVGNSLITMYSKSGQVEDA 426          

Query:   19 QGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFG-KMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMP-ERDVACWNTVI 495
            +G+ IH +++  GL+++  +C  L++ Y  C   D+A LVF  +E+ + IS W  ++TGF K+     A+E+F  +L    I P+  TY +VL AC   G V  G K       K G V  +   + +V +  +      A+   + MP   D   W T +
Sbjct:  491 KGEQIHARIIKSGLESNQIICNXLVSMYSRCGNIDAAFLVFNEMEDWNVIS-WTSMITGFAKHGYAAAAVEMFNKMLE-AGIKPNXITYIAVLSACSHAGLVDEGWKHFKEMQKKHGVVPRMEHYACMVDLLGRSGSLVEALEFINSMPFTADELIWRTFL 649          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPY-IGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMR--NSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMG-ALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            G+++H   + +GL +D  +   LI  Y  C   + A  +F+ +   + +S WN ++ GF++N +  E+  L   +L     + PD  T  +VL  C   G+V  G MIH+  +K G   +++V ++L  MY KC     A  LFD+  +++V  WN+VI  + ++G      +L  KM+        N VT+  V+ +C    +L    ++H    +   + D  V +A V  Y KCG L+ A+ VF  I  K V +WN++I   +  GD    +  + +M   G  P   +  S+LLAC+    L HG+ IH F++RN +E D +I  SL+ +Y   G +SSA+ +F++     +VSWN MI+GY +VG    AL ++  M    + P  I   S+  ACSQL+AL  GKE+H   + +   T ++ +G +L+DMYAK G ++++  VF+RL  +D  SW  +I  YG HG   +AL+LF EM     KPDG T + +L+ACSH GLV EG  +FNQM + Y I+P++EHY+C++D+LGRAGRL EA  ++    E   D  + S+L S+CR H NLD+G KIA  L++  P+    Y++LSN YA+  KWD V+ VR KMKE+GL+K+ G SWIE+  +++ F VGD S P+S
Sbjct:  214 GQVVHGMAVKMGLISDVFVGNALIAMYGKCGSVEDAAKMFEIMPEKNLVS-WNSMICGFSENGLDHESYSLLGKILESEEALVPDVATLVTVLPLCAGNGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVSWNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRNGLEMDSFIGISLLSVYIHCGKLSSARILFDRTESKISVSWNAMIAGYTQVGLPDKALDLFRQMLSDEILPCEIATMSMFGACSQLSALRSGKELHCFALKARL-TEDLFVGCSLIDMYAKSGCIEQSHRVFDRLTKKDVPSWNVIIAGYGIHGHGNKALELFREMLSFGQKPDGFTFIGILTACSHAGLVKEGIEYFNQMQSLYKIEPKLEHYACVVDMLGRAGRLEEALNLIHEMPE-EPDTRMWSSLLSSCRSHNNLDMGQKIAEKLLDLEPEKAENYVLLSNLYAASGKWDSVRNVRRKMKEIGLQKDAGRSWIELGGQVYSFVVGDTSLPES 865          

Query:   13 LKQGKLIHQKM-LTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNS--GFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTL--TTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEH---YSC-LIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIE--KNPD 1791
            ++ G+ +H  +  +    +D  L   +I  Y  C     ++ VF  ++   ++  WN +++G+ +N +FV+A++LF  L+      PD++T+P V KACG +  VG G+++H   +K G +SD+ V ++L+ MY KC   + A ++F+ MPE+++  WN++I  + ++G   ++  L  K+  S     P+  TL TV+  CA   ++  GM IH   +K  L  +  V +AL DMY KCG    A+ +F++   KNVV+WNS+I  +S  GD        R+M  E     +   T  ++L AC   ++LL  K +HA+  R+    D  + ++ +  Y   GS++SA+ VF  +      SWN +I G  + GD + AL +Y  MK +G+ P+  ++ S+L AC+ L  L+ G+EIH  V+ +  E +  +  +LL +Y  CG +  A  +F+R  ++  VSW +MI  Y   G   +AL LF +M      P  +  +++  ACS +  +  G     + +  + +K R+       C LID+  ++G + +++ +  R +  ++DV   + + +   +H + +  +++ R ++   + PD
Sbjct:  108 VETGRKVHNLVSASTVFSSDFVLNTRIITMYAMCGSPLDSRSVFDGLKR-KNLFQWNALVSGYARNELFVDAIDLFVELISVTEFKPDNFTFPCVFKACGGISDVGLGQVVHGMAVKMGLISDVFVGNALIAMYGKCGSVEDAAKMFEIMPEKNLVSWNSMICGFSENGLDHESYSLLGKILESEEALVPDVATLVTVLPLCAGNGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVSWNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRNGLEMDSFIGISLLSVYIHCGKLSSARILFDRTESKISVSWNAMIAGYTQVGLPDKALDLFRQMLSDEILPCEIATMSMFGACSQLSALRSG-----KELHCFALKARLTEDLFVGCSLIDMYAKSGCIEQSHRVFDRLT--KKDVPSWNVIIAGYGIHGHGNKALELFREMLSFGQKPD 703          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESL-LRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVID-SEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNR-DPVSWTSMITAYGSHGQALEALKLFGE-MQQSNAKPDGVTLLAVLSACS 1521
            N  +  G +IH   + LGL  +  +   L + Y  C +   A+++F   +  + +S WN V+ GF++        +L   + +    +  +  T  +VL AC    ++   K +H +  +  F+ D +VA++ V  Y KC   + A  +F  +  + V  WN VI    Q+G   KA++L+ +M+ SG  P+  ++ +++ +CA L  L+ G +IH  ++++ L +DSF+  +L+ +Y  CG L  A+ +F++   K  V+WN+MIA Y+  G     +  FR+M  +   P      S+  ACS+ + L  GK +H F ++  +  D+++  SLID+Y  SG +  +  VF+++ K +  SWNV+I+GY   G    AL ++ +M   G +P+  T   IL+ACS    +++G E    +    + E        ++DM  + G ++EALN+ + +P   D   W+S++++  SH       K+  + +     K +   LL+ L A S
Sbjct:  311 NGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVS-WNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRNGLEMDSFIGISLLSVYIHCGKLSSARILFDRTESKISVSWNAMIAGYTQVGLPDKALDLFRQMLSDEILPCEIATMSMFGACSQLSALRSGKELHCFALKARLTEDLFVGCSLIDMYAKSGCIEQSHRVFDRLTKKDVPSWNVIIAGYGIHGHGNKALELFREMLSFGQKPDGFTFIGILTACSHAGLVKEGIEYFNQMQSLYKIEPKLEHYACVVDMLGRAGRLEEALNLIHEMPEEPDTRMWSSLLSSCRSHNNLDMGQKIAEKLLDLEPEKAENYVLLSNLYAAS 819          

Query:  289 SVLKACGALGQVGFGKMIHNHL-IKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELF-EKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRM--NREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYD--DMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRT 1674
            ++L+ACG    V  G+ +HN +   T F SD V+ + ++ MYA C     +  +FD +  +++  WN ++S Y ++     A++LF E +  + F P++ T   V  +C  + D+  G  +H   +K  L+ D FV +AL+ MYGKCG ++ A ++FE +P KN+V+WNSMI  +S  G          ++  + E   P + T  ++L  C+ + ++  G  IH+  ++  +  ++ + ++L D+Y   G    A+ +F+K  K N VSWN +I G+ + GD  G   +     M+E  V+ N +T+ ++L AC + + L   KE+H       F  +E++  A +  Y KCG+++ A  VF+ +  +   SW ++I     +G   +AL L+ +M+ S   PD  ++ ++L AC+H+  +  G      ++ N G++        L+ +    G+L+ A  +  RT
Sbjct:   97 TLLQACGRRKDVETGRKVHNLVSASTVFSSDFVLNTRIITMYAMCGSPLDSRSVFDGLKRKNLFQWNALVSGYARNELFVDAIDLFVELISVTEFKPDNFTFPCVFKACGGISDVGLGQVVHGMAVKMGLISDVFVGNALIAMYGKCGSVEDAAKMFEIMPEKNLVSWNSMICGFSENGLDHESYSLLGKILESEEALVPDVATLVTVLPLCAGNGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVSWNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRN-GLEMDSFIGISLLSVYIHCGKLSSARILFDRT 563          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPY-IGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMR--NSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMG-ALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQS 1974
            G+++H   + +GL +D  +   LI  Y  C   + A  +F+ +   + +S WN ++ GF++N +  E+  L   +L     + PD  T  +VL  C   G+V  G MIH+  +K G   +++V ++L  MY KC     A  LFD+  +++V  WN+VI  + ++G      +L  KM+        N VT+  V+ +C    +L    ++H    +   + D  V +A V  Y KCG L+ A+ VF  I  K V +WN++I   +  GD    +  + +M   G  P   +  S+LLAC+    L HG+ IH F++RN +E D +I  SL+ +Y   G +SSA+ +F++     +VSWN MI+GY +VG    AL ++  M    + P  I   S+  ACSQL+AL  GKE+H   + +   T ++ +G +L+DMYAK G ++++  VF+RL  +D  SW  +I  YG HG   +AL+LF EM     KPDG T + +L+ACSH GLV EG  +FNQM + Y I+P++EHY+C++D+LGRAGRL EA  ++    E   D  + S+L S+CR H NLD+G KIA  L++  P+    Y++LSN YA+  KWD V+ VR KMKE+GL+K+ G SWIE+  +++ F VGD S P+S
Sbjct:  214 GQVVHGMAVKMGLISDVFVGNALIAMYGKCGSVEDAAKMFEIMPEKNLVS-WNSMICGFSENGLDHESYSLLGKILESEEALVPDVATLVTVLPLCAGNGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVSWNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRNGLEMDSFIGISLLSVYIHCGKLSSARILFDRTESKISVSWNAMIAGYTQVGLPDKALDLFRQMLSDEILPCEIATMSMFGACSQLSALRSGKELHCFALKARL-TEDLFVGCSLIDMYAKSGCIEQSHRVFDRLTKKDVPSWNVIIAGYGIHGHGNKALELFREMLSFGQKPDGFTFIGILTACSHAGLVKEGIEYFNQMQSLYKIEPKLEHYACVVDMLGRAGRLEEALNLIHEMPE-EPDTRMWSSLLSSCRSHNNLDMGQKIAEKLLDLEPEKAENYVLLSNLYAASGKWDSVRNVRRKMKEIGLQKDAGRSWIELGGQVYSFVVGDTSLPES 865          

Query:   13 LKQGKLIHQKM-LTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNS--GFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTL--TTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEH---YSC-LIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIE--KNPD 1791
            ++ G+ +H  +  +    +D  L   +I  Y  C     ++ VF  ++   ++  WN +++G+ +N +FV+A++LF  L+      PD++T+P V KACG +  VG G+++H   +K G +SD+ V ++L+ MY KC   + A ++F+ MPE+++  WN++I  + ++G   ++  L  K+  S     P+  TL TV+  CA   ++  GM IH   +K  L  +  V +AL DMY KCG    A+ +F++   KNVV+WNS+I  +S  GD        R+M  E     +   T  ++L AC   ++LL  K +HA+  R+    D  + ++ +  Y   GS++SA+ VF  +      SWN +I G  + GD + AL +Y  MK +G+ P+  ++ S+L AC+ L  L+ G+EIH  V+ +  E +  +  +LL +Y  CG +  A  +F+R  ++  VSW +MI  Y   G   +AL LF +M      P  +  +++  ACS +  +  G     + +  + +K R+       C LID+  ++G + +++ +  R +  ++DV   + + +   +H + +  +++ R ++   + PD
Sbjct:  108 VETGRKVHNLVSASTVFSSDFVLNTRIITMYAMCGSPLDSRSVFDGLKR-KNLFQWNALVSGYARNELFVDAIDLFVELISVTEFKPDNFTFPCVFKACGGISDVGLGQVVHGMAVKMGLISDVFVGNALIAMYGKCGSVEDAAKMFEIMPEKNLVSWNSMICGFSENGLDHESYSLLGKILESEEALVPDVATLVTVLPLCAGNGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVSWNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRNGLEMDSFIGISLLSVYIHCGKLSSARILFDRTESKISVSWNAMIAGYTQVGLPDKALDLFRQMLSDEILPCEIATMSMFGACSQLSALRSG-----KELHCFALKARLTEDLFVGCSLIDMYAKSGCIEQSHRVFDRLT--KKDVPSWNVIIAGYGIHGHGNKALELFREMLSFGQKPD 703          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESL-LRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVID-SEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNR-DPVSWTSMITAYGSHGQALEALKLFGE-MQQSNAKPDGVTLLAVLSACS 1521
            N  +  G +IH   + LGL  +  +   L + Y  C +   A+++F   +  + +S WN V+ GF++        +L   + +    +  +  T  +VL AC    ++   K +H +  +  F+ D +VA++ V  Y KC   + A  +F  +  + V  WN VI    Q+G   KA++L+ +M+ SG  P+  ++ +++ +CA L  L+ G +IH  ++++ L +DSF+  +L+ +Y  CG L  A+ +F++   K  V+WN+MIA Y+  G     +  FR+M  +   P      S+  ACS+ + L  GK +H F ++  +  D+++  SLID+Y  SG +  +  VF+++ K +  SWNV+I+GY   G    AL ++ +M   G +P+  T   IL+ACS    +++G E    +    + E        ++DM  + G ++EALN+ + +P   D   W+S++++  SH       K+  + +     K +   LL+ L A S
Sbjct:  311 NGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVS-WNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRNGLEMDSFIGISLLSVYIHCGKLSSARILFDRTESKISVSWNAMIAGYTQVGLPDKALDLFRQMLSDEILPCEIATMSMFGACSQLSALRSGKELHCFALKARLTEDLFVGCSLIDMYAKSGCIEQSHRVFDRLTKKDVPSWNVIIAGYGIHGHGNKALELFREMLSFGQKPDGFTFIGILTACSHAGLVKEGIEYFNQMQSLYKIEPKLEHYACVVDMLGRAGRLEEALNLIHEMPEEPDTRMWSSLLSSCRSHNNLDMGQKIAEKLLDLEPEKAENYVLLSNLYAAS 819          

Query:  289 SVLKACGALGQVGFGKMIHNHL-IKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELF-EKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRM--NREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYD--DMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRT 1674
            ++L+ACG    V  G+ +HN +   T F SD V+ + ++ MYA C     +  +FD +  +++  WN ++S Y ++     A++LF E +  + F P++ T   V  +C  + D+  G  +H   +K  L+ D FV +AL+ MYGKCG ++ A ++FE +P KN+V+WNSMI  +S  G          ++  + E   P + T  ++L  C+ + ++  G  IH+  ++  +  ++ + ++L D+Y   G    A+ +F+K  K N VSWN +I G+ + GD  G   +     M+E  V+ N +T+ ++L AC + + L   KE+H       F  +E++  A +  Y KCG+++ A  VF+ +  +   SW ++I     +G   +AL L+ +M+ S   PD  ++ ++L AC+H+  +  G      ++ N G++        L+ +    G+L+ A  +  RT
Sbjct:   97 TLLQACGRRKDVETGRKVHNLVSASTVFSSDFVLNTRIITMYAMCGSPLDSRSVFDGLKRKNLFQWNALVSGYARNELFVDAIDLFVELISVTEFKPDNFTFPCVFKACGGISDVGLGQVVHGMAVKMGLISDVFVGNALIAMYGKCGSVEDAAKMFEIMPEKNLVSWNSMICGFSENGLDHESYSLLGKILESEEALVPDVATLVTVLPLCAGNGEVNMGMMIHSLAVKLGLNQELMVNNALADMYLKCGYSVEAQVLFDKNDKKNVVSWNSVIGGFSREGDVCGTFDLLRKMQMEEEKVKVNEVTILNVLPACLEESELLSLKELHAYSFRHWFIYDELVANAFVAAYTKCGSLNSAELVFHGIETKTVGSWNAVIGGCAQNGDPYKALDLYLQMKYSGLDPDEFSIGSLLLACAHLKHLQHGREIHGFVLRN-GLEMDSFIGISLLSVYIHCGKLSSARILFDRT 563          

Query:   55 GLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            GL N+      L++ + +    + A  VF ++E+   +  ++ ++ G+ KN    +A   F   ++Y  + P  Y +  +LK CG    +  GK IH  LI +GF S++   +++V +YAKC   D A ++FD MPERD+  WNT+++ Y Q+G A+ AMEL  +M+  G  P+ +TL T++ + A    L  G  IH  +++        +++ALVDMY KCG +  A+ +F ++  K VV+WNSMI  Y    D    ++ F++M  +G  PT  T    L AC+    L  G F+H  + +  + +D+ + +SLI +Y     V  A  +F K+     VSWN MI GY + G    AL+ + +M    ++P++ T+ S++ A ++L+   + K IH  VI   F+ N  +M AL+DMYAKCGAV  A  +F+ +  R   +W +MI  YG++G    A+ LF EM++   KP+ +T L V+SACSH GLV+EG  +F  M  +YG++P ++HY  ++DLLGRAGRL EA++ +Q    +   + +   +  ACR+H+N++LG K A  + + NP D   +++L+N Y +   WD+V  VR  M++ GL+K PGCS +++  ++H F+ G  SHPQS+
Sbjct:   87 GLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEV-FYHTLLKGYAKNSSLGDAFSFF-CRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHSARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGRLYEAWDFIQ-NMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFKLNPADGGYHVLLANIYQTASLWDKVANVRTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSK 724          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIG--PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTV-IDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLP 1371
            N  L++GK IH  +++ G  ++      ++N Y  C   D A  +F  +     +S WN ++ G+ +N +   A+EL   ++R    G  PD  T  ++L A    G +  GK IH ++++ GF S + ++++LV MY+KC     A  +F  M  + V  WN++I  Y Q+   ++AME+F+KM + GF P +VT+   + +CA L DLERGM +HK L + +L  D  V ++L+ MY KC  +D+A ++F ++  K  V+WN+MI  Y+  G     +  F  M+ +   P   T  S++ A +  +     K+IH  +IR   + ++++ ++L+D+Y   G+V SA+ +F+ M + +  +WN MI GY   G    A+ ++++MK+  ++PN IT   ++SACS    +E+G +   ++  D   E      GA++D+  + G + EA +    +P
Sbjct:  171 NADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVS-WNTIVAGYAQNGLAKIAMEL---VIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHSARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGTIKPNDITFLCVISACSHSGLVEEGLQYFASMKEDYGLEPAMDHYGAMVDLLGRAGRLYEAWDFIQNMP 625          

Query:   55 GLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            GL N+      L++ + +    + A  VF ++E+   +  ++ ++ G+ KN    +A   F   ++Y  + P  Y +  +LK CG    +  GK IH  LI +GF S++   +++V +YAKC   D A ++FD MPERD+  WNT+++ Y Q+G A+ AMEL  +M+  G  P+ +TL T++ + A    L  G  IH  +++        +++ALVDMY KCG +  A+ +F ++  K VV+WNSMI  Y    D    ++ F++M  +G  PT  T    L AC+    L  G F+H  + +  + +D+ + +SLI +Y     V  A  +F K+     VSWN MI GY + G    AL+ + +M    ++P++ T+ S++ A ++L+   + K IH  VI   F+ N  +M AL+DMYAKCGAV  A  +F+ +  R   +W +MI  YG++G    A+ LF EM++   KP+ +T L V+SACSH GLV+EG  +F     +YG++P ++HY  ++DLLGRAGRL EA++ +Q    +   + +   +  ACR+H+N++LG K A  +   NP D   +++L+N Y +   WD+V  V   M++ GL+K PGCS +++  ++H F+ G  SHPQS+
Sbjct:  247 GLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEV-FYHTLLKGYAKNSSLGDAFSFF-CRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQ-NMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFXLNPADGGYHVLLANIYQTASLWDKVAXVXTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSK 884          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIG--PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTV-IDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLP 1371
            N  L++GK IH  +++ G  ++      ++N Y  C   D A  +F  +     +S WN ++ G+ +N +   A+EL   ++R    G  PD  T  ++L A    G +  GK IH ++++ GF S + ++++LV MY+KC     A  +F  M  + V  WN++I  Y Q+   ++AME+F+KM + GF P +VT+   + +CA L DLERGM +HK L + +L  D  V ++L+ MY KC  +D+A ++F ++  K  V+WN+MI  Y+  G     +  F  M+ +   P   T  S++ A +  +     K+IH  +IR   + ++++ ++L+D+Y   G+V  A+ +F+ M + +  +WN MI GY   G    A+ ++++MK+  ++PN IT   ++SACS    +E+G +   +   D   E      GA++D+  + G + EA +    +P
Sbjct:  331 NADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVS-WNTIVAGYAQNGLAKIAMEL---VIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKSAVDLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQNMP 785          

Query:  352 LIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSE 1680
            +IK G  ++ +  + LV ++      + A R+FD + ++    ++T++  Y ++     A   F +M+  G  P     T ++  C    DL RG +IH +LI      + F  +A+V++Y KC  +D A ++F+++P +++V+WN+++A Y+  G +   ++   RM  EG  P   T  ++L A +    L+ GK IHA+++R   E+ + + ++L+D+Y   GSV +A+ +F +M     VSWN MI GYV+  D   A+ ++  M + G  P  +T+   L AC+ L  LE+G  +H+ +   +  ++  +M +L+ MY+KC  VD A  +FN+L  + PVSW +MI  Y  +G+  EAL  F EM   N KPD  T+++V+ A + +  V     + + ++        +   + L+D+  + G ++ A ++     E
Sbjct:  243 IIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELS-VTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDE 684          

Query:   55 GLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            GL N+      L++ + +    + A  VF ++E+   +  ++ ++ G+ KN    +A   F   ++Y  + P  Y +  +LK CG    +  GK IH  LI +GF S++   +++V +YAKC   D A ++FD MPERD+  WNT+++ Y Q+G A+ AMEL  +M+  G  P+ +TL T++ + A    L  G  IH  +++        +++ALVDMY KCG +  A+ +F ++  K VV+WNSMI  Y    D    ++ F++M  +G  PT  T    L AC+    L  G F+H  + +  + +D+ + +SLI +Y     V  A  +F K+     VSWN MI GY + G    AL+ + +M    ++P++ T+ S++ A ++L+   + K IH  VI   F+ N  +M AL+DMYAKCGAV  A  +F+ +  R   +W +MI  YG++G    A+ LF EM++   KP+ +T L V+SACSH GLV+EG  +F     +YG++P ++HY  ++DLLGRAGRL EA++ +Q    +   + +   +  ACR+H+N++LG K A  +   NP D   +++L+N Y +   WD+V  V   M++ GL+K PGCS +++  ++H F+ G  SHPQS+
Sbjct:   87 GLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEV-FYHTLLKGYAKNSSLGDAFSFF-CRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKXAVXLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQ-NMPMEPGITVFGAMLGACRIHKNIELGEKAADKIFXLNPADGGYHVLLANIYQTASLWDKVAXVXTMMEKKGLQKTPGCSLVDLKNEVHTFYSGSTSHPQSK 724          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIG--PDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTV-IDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLP 1371
            N  L++GK IH  +++ G  ++      ++N Y  C   D A  +F  +     +S WN ++ G+ +N +   A+EL   ++R    G  PD  T  ++L A    G +  GK IH ++++ GF S + ++++LV MY+KC     A  +F  M  + V  WN++I  Y Q+   ++AME+F+KM + GF P +VT+   + +CA L DLERGM +HK L + +L  D  V ++L+ MY KC  +D+A ++F ++  K  V+WN+MI  Y+  G     +  F  M+ +   P   T  S++ A +  +     K+IH  +IR   + ++++ ++L+D+Y   G+V  A+ +F+ M + +  +WN MI GY   G    A+ ++++MK+  ++PN IT   ++SACS    +E+G +   +   D   E      GA++D+  + G + EA +    +P
Sbjct:  171 NADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVS-WNTIVAGYAQNGLAKIAMEL---VIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELSVTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDERHVTTWNAMIDGYGTNGLGKXAVXLFNEMKKGXIKPNDITFLCVISACSHSGLVEEGLQYFASXKEDYGLEPAMDHYGAMVDLLGRAGRLXEAWDFIQNMP 625          

Query:  229 ELFESLLRYPYIGPDSYTYPS--VLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSE 1680
            + F +L +  +I    Y +P+  +L+ C +  ++     I   +IK G  ++ +  + LV ++      + A R+FD + ++    ++T++  Y ++     A   F +M+  G  P     T ++  C    DL RG +IH +LI      + F  +A+V++Y KC  +D A ++F+++P +++V+WN+++A Y+  G +   ++   RM  EG  P   T  ++L A +    L+ GK IHA+++R   E+ + + ++L+D+Y   GSV +A+ +F +M     VSWN MI GYV+  D   A+ ++  M + G  P  +T+   L AC+ L  LE+G  +H+ +   +  ++  +M +L+ MY+KC  VD A  +FN+L  + PVSW +MI  Y  +G+  EAL  F EM   N KPD  T+++V+ A + +  V     + + ++        +   + L+D+  + G ++ A ++     E
Sbjct:   43 QTFHTLSQRTHIPSHVYKHPAAILLELCTSXQELN---QIIPLIIKNGLYNEHLFQTKLVSLFCNYGCPNEAARVFDTVEDKLEVFYHTLLKGYAKNSSLGDAFSFFCRMKYDGVKPVVYNFTYLLKVCGDNADLRRGKEIHGDLISSGFASNLFAMTAVVNLYAKCRQVDEAYKMFDRMPERDLVSWNTIVAGYAQNGLAKIAMELVIRMQEEGQKPDPITLVTLLPAVADFGSLIIGKSIHAYVVRAGFESHVNLSTALVDMYSKCGSVGTARLIFXRMKHKTVVSWNSMIDGYVQNEDPKEAMEVFQKMLDQGFEPTNVTIMEALHACADLGDLERGMFVHKLLDQMKLGSDVSVMNSLISMYSKCKRVDIAAKIFNKLQGKTPVSWNAMILGYAQNGRVSEALSHFXEMHSQNIKPDSFTMVSVIPAIAELS-VTRQAKWIHGLVIRKCFDKNVFVMTALVDMYAKCGAVHXARKLFDMMDE 524          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            LKQGKLIHQK+++LGLQN+  LCK+LIN YFSCH   SAKLVFQ+IENP  I+LWNG+M   TKN +F+E LE+F  LL +PY+ PD++TYPSVLKAC  LG+VG+GKM+H H+IK+GF  D+VV SS V MYAKCNVF+ AI+LFDEMPERDVA WN VISCYYQDGQ +KA+ELFE+M+ SGF P+SVTLTTVISSCARL DLERG +IH EL++    LD FV+SALVDMYGKCGCL+MAKEVFEQI  KNVV+WNSMIA YS+ GDS SCI+ FRRM+ EG  PTLTT SSIL+ACSRS  L  GKFIH ++IRN +EADI++ SSLIDLYF  G++ SA+NVF+ MPKTN VSWNVMISGYVKVG Y  AL I+ DM++AGV+P+AIT TS+L ACSQLA LEKGKEIH  +I+S+ E NE++MGALLDMYAKCGAVDEAL++FN+LP RD VSWTSMI AYGSHGQA EALKLF +MQQS+AKPD VT LA+LSACSH GLVDEGC++FNQMI  YG KP +EHYSCLIDLLGR GRL EAYEILQRT +IREDV LLSTLFSAC LH+ LDLG +I RLLIEK+PDD STYI+LSN YASVKKWDEV+KVRLK+KELGL+KNPGCSWIE+ K+IHPF V DKSHPQ++M
Sbjct:   19 LKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPDIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYIILSNMYASVKKWDEVRKVRLKIKELGLKKNPGCSWIEVGKRIHPFVVEDKSHPQADM 674          

Query:  289 SVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPE-RDVACWNTVISCYYQDGQAQKAMELFEKMRNSGF-TPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIE----HYSCLIDLLGRAGRLNEAYEILQRTSE 1680
            S+LK C     +  GK+IH  ++  G  ++I +  SL+ +Y  C++F  A  +F  +    D+  WN +++   ++    + +E+F ++ +  +  P++ T  +V+ +C+ L  +  G  +H  +IK    +D  V S+ V MY KC   + A ++F+++P ++V +WN++I+ Y   G     ++ F  M   G  P   T ++++ +C+R   L  GK IH  ++R+    D ++ S+L+D+Y   G +  AK VFE++ + N VSWN MI+GY   GD    + ++  M E G+RP   T++SIL ACS+   L+ GK IH  +I +  E +  +  +L+D+Y KCG +  A NVF  +P  + VSW  MI+ Y   G  LEAL +F +M+++  KPD +T  +VL ACS + ++++G     + I N+ I+ ++E        L+D+  + G ++EA  I  +  E
Sbjct:    8 SLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKG-----KEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPE 472          

Query:  574 NSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQI--PIKNVVAWNSMIAAYSVTGDSISCIQFFRR-MNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEH----YSCLIDLLGRAGRLNEAYEILQ 1668
            ++  L +++ +C     L++G  IH++++   L  +  +  +L+++Y  C     AK VF+ I  P+ ++  WN ++AA +     I  ++ F R ++     P   T+ S+L ACS   ++ +GK +H  +I++    D+ + SS + +Y        A  +F++MP+ +  SWN +IS Y + G    AL ++++MK +G +P+++T+T+++S+C++L  LE+GKEIH  ++ S F  +  +  AL+DMY KCG ++ A  VF ++  ++ VSW SMI  Y   G +   ++LF  M +   +P   TL ++L ACS    +  G     + I  Y I+ R+E      S LIDL  + G +  A  + Q
Sbjct:    2 DTTKLLSLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPL-DITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLG-----KFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQ 367          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD---QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIP 765
            +L+ GK IH  ++   ++ D  +  +LI+ YF C    SA+ VFQ++   + +S WN +++G+ K   ++EAL +F   +R   + PD+ T+ SVL AC  L  +  GK IHN +I++    + VV  +L+ MYAKC   D A+ +F+++PERD   W ++I+ Y   GQA +A++LFEKM+ S   P+ VT   ++S+C+    ++ G     ++I +   +  ++ +  S L+D+ G+ G L  A E+ ++ P
Sbjct:  323 NLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVS-WNVMISGYVKVGSYLEALVIFTD-MRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHY--SCLIDLLGRVGRLREAYEILQRTP 573          

Query:  883 TTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVS-WNVMISGYVKVGDYFGALAIYDDMKE-AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMI-TNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            T   S+L  C  S  L  GK IH  ++   ++ +I +  SLI+LYF      SAK VF+ +     ++ WN +++   K   +   L ++  +     ++P+A T  S+L ACS L  +  GK +H  VI S F  + ++M + + MYAKC   ++A+ +F+ +P RD  SW ++I+ Y   GQ  +AL+LF EM+ S  KPD VTL  V+S+C+ +  ++ G     +++ + + +   +   S L+D+ G+ G L  A E+ ++
Sbjct:    4 TKLLSLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVS--SALVDMYGKCGCLEMAKEVFEQ 267          

Query:   22 GKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            GKLIHQK+++LGLQN+  LCK+LIN YFSCH   SAKLVFQ+IENP  I+LWNG+M   TKN +F+E LE+F  LL +PY+ PD++TYPSVLKAC  LG+VG+GKM+H H+IK+GF  D+VV SS V MYAKCNVF+ AI+LFDEMPERDVA WN VISCYYQDGQ +KA+ELFE+M+ SGF P+SVTLTTVISSCARL DLERG +IH EL++    LD FV+SALVDMYGKCGCL+MAKEVFEQI  KNVV+WNSMIA YS+ GDS SCI+ FRRM+ EG  PTLTT SSIL+ACSRS  L  GKFIH ++IRN +EADI++ SSLIDLYF  G++ SA+NVF+ MPKTN VSWNVMISGYVKVG Y  AL I+ DM++AGV+P+AIT TS+L ACSQLA LEKGKEIH  +I+S+ E NE++MGALLDMYAKCGAVDEAL++FN+LP RD VSWTSMI AYGSHGQA EALKLF +MQQS+AKPD VT LA+LSACSH GLVDEGC++FNQMI  YG KP +EHYSCLIDLLGR GRL EAYEILQRT +IREDV LLSTLFSAC LH+ LDLG +I RLLIEK+PDD STYI+LSN YASVKKWDEV+KVRLK+KELGL+KNPGCSWIE+ K+IHPF V DKSHPQ++M
Sbjct:  214 GKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPDIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYIILSNMYASVKKWDEVRKVRLKIKELGLKKNPGCSWIEVGKRIHPFVVEDKSHPQADM 866          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNI-IEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNV 1356
            L++GK IH +++  G   D  +   L++ Y  C   + AK VF+ I+  + +S WN ++ G++        +ELF   +    I P   T  S+L AC     +  GK IH ++I+    +DI V SSL+ +Y KC     A  +F  MP+ +V  WN +IS Y + G   +A+ +F  MR +G  P+++T T+V+ +C++L  LE+G +IH  +I+ +L ++  V  AL+DMY KCG +D A  +F Q+P ++ V+W SMIAAY   G +   ++ F +M +    P   TF +IL ACS +  +  G +    MI     +  +  YS LIDL    G +  A  + ++ P                                  +R +   ++++ SAC     L+ G++I R +I+ + +     +  L +MYA     DE   V
Sbjct:  415 LERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVS-WNSMIAGYSLKGDSKSCIELFRR-MDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTP---------------------------------DIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYI-ILSNMYASVKKWDEVRKV 827          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD---QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIP 765
            +L+ GK IH  ++   ++ D  +  +LI+ YF C    SA+ VFQ++   + +S WN +++G+ K   ++EAL +F   +R   + PD+ T+ SVL AC  L  +  GK IHN +I++    + VV  +L+ MYAKC   D A+ +F+++PERD   W ++I+ Y   GQA +A++LFEKM+ S   P+ VT   ++S+C+    ++ G     ++I +   +  ++ +  S L+D+ G+ G L  A E+ ++ P
Sbjct:  515 NLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVS-WNVMISGYVKVGSYLEALVIFTD-MRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVVMGALLDMYAKCGAVDEALHIFNQLPERDFVSWTSMIAAYGSHGQAFEALKLFEKMQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHY--SCLIDLLGRVGRLREAYEILQRTP 765          

Query:  931 LHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVS-WNVMISGYVKVGDYFGALAIYDDMKE-AGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMI-TNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            L GK IH  ++   ++ +I +  SLI+LYF      SAK VF+ +     ++ WN +++   K   +   L ++  +     ++P+A T  S+L ACS L  +  GK +H  VI S F  + ++M + + MYAKC   ++A+ +F+ +P RD  SW ++I+ Y   GQ  +AL+LF EM+ S  KPD VTL  V+S+C+ +  ++ G     +++ + + +   +   S L+D+ G+ G L  A E+ ++
Sbjct:  212 LLGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEVFHRLLHFPYLKPDAFTYPSVLKACSGLGRVGYGKMVHTHVIKSGFAMDVVVMSSAVGMYAKCNVFEDAIKLFDEMPERDVASWNNVISCYYQDGQPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVS--SALVDMYGKCGCLEMAKEVFEQ 459          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            + SLKQGKLIHQK++TLGLQND  LCKNLIN Y SCH  D AK VF ++ENP  ISLWNG+M G+TKN+M+VEALELFE LL YPY+ PDSYTYPSVLKACG L +   GKMIH  L+KTG + DIVV SSLV MYAKCN F+ AI LF+EMPE+DVACWNTVISCYYQ G  ++A+E F  MR  GF PNSVT+TT ISSCARL DL RGM+IH+ELI    +LDSF++SALVDMYGKCG L+MA EVFEQ+P K VVAWNSMI+ Y + GDSISCIQ F+RM  EG  PTLTT SS+++ CSRSA+LL GKF+H + IRN I++D++I SSL+DLYF  G V  A+N+F+ +PK+  VSWNVMISGYV  G  F AL ++ +M+++ V P+AIT TS+L+ACSQLAALEKG+EIH  +I+ + + NE++MGALLDMYAKCGAVDEA +VF  LP RD VSWTSMITAYGSHGQA  AL+LF EM QSN KPD VT LA+LSAC H GLVDEGC++FNQM+  YGI PR+EHYSCLIDLLGRAGRL+EAYEILQ+  EIR+DV+LLSTLFSACRLHRN+DLG +IAR LI+K+PDD STYI+LSN YAS  KWDEV+ VR KMKELGL+KNPGCSWIEIN+KI PFFV D SH   E+
Sbjct:   16 SKSLKQGKLIHQKVVTLGLQNDIFLCKNLINLYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVLKACGGLYKYVLGKMIHTCLVKTGLMMDIVVGSSLVGMYAKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKEALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEVFEQMPKKTVVAWNSMISGYGLKGDSISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEGKFVHGYTIRNRIQSDVFINSSLMDLYFKCGKVELAENIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVEPDAITFTSVLTACSQLAALEKGEEIHNLIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSVFKCLPKRDLVSWTSMITAYGSHGQAYVALELFAEMLQSNMKPDRVTFLAILSACGHAGLVDEGCYYFNQMVNVYGIIPRVEHYSCLIDLLGRAGRLHEAYEILQQNPEIRDDVELLSTLFSACRLHRNIDLGAEIARTLIDKDPDDSSTYILLSNMYASAHKWDEVRVVRSKMKELGLKKNPGCSWIEINQKILPFFVEDNSHLHLEL 674          

Query:  292 VLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISCYYQDGQAQKAMELFEKMRNSGF-TPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEH----YSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKN-PDDHSTYIML 1815
            +L+AC     +  GK+IH  ++  G  +DI +  +L+ +Y  C+++D A  +FD M    +++ WN +++ Y ++    +A+ELFEK+ +  +  P+S T  +V+ +C  L+    G  IH  L+K  L++D  V S+LV MY KC   + A  +F ++P K+V  WN++I+ Y  +G+    +++F  M R G  P   T ++ + +C+R   L  G  IH  +I +    D +I S+L+D+Y   G +  A  VFE+MPK   V+WN MISGY   GD    + ++  M   GV+P   T++S++  CS+ A L +GK +H   I +  +++  +  +L+D+Y KCG V+ A N+F  +P    VSW  MI+ Y + G+  EAL LF EM++S  +PD +T  +VL+ACS +  +++G     + I N  I+ ++++       L+D+  + G ++EA+ + +     + D+   +++ +A   H    + +++   +++ N   D  T++ +
Sbjct:    9 LLRACMNSKSLKQGKLIHQKVVTLGLQNDIFLCKNLINLYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVLKACGGLYKYVLGKMIHTCLVKTGLMMDIVVGSSLVGMYAKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKEALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEVFEQMPKKTVVAWNSMISGYGLKGDSISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEGKFVHGYTIRNRIQSDVFINSSLMDLYFKCGKVELAENIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVEPDAITFTSVLTACSQLAALEKG-----EEIHNLIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSVFKCLP--KRDLVSWTSMITAYGSHGQAYVALELFAEMLQSNMKPDRVTFLAI 516          

Query:  586 LTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGDSISCIQFFRR-MNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEH----YSCLIDLLGRAGRLNEAYEILQ---------------------------------RTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYI-MLSNTYASVKKWDEVKKV 1863
            L  ++ +C     L++G  IH++++   L  D F+   L+++Y  C   D AK VF+ +     +  WN ++A Y+     +  ++ F + ++     P   T+ S+L AC    + + GK IH  +++  +  DI + SSL+ +Y    +   A  +F +MP+ +   WN +IS Y + G++  AL  +  M+  G  PN++T+T+ +S+C++L  L +G EIH  +I+S F  +  +  AL+DMY KCG ++ A+ VF ++P +  V+W SMI+ YG  G ++  ++LF  M     KP   TL +++  CS    + EG     + +  Y I+ RI+      S L+DL  + G++  A  I +                                 R S +  D    +++ +AC     L+ G +I  L+IEK  D++   +  L + YA     DE   V
Sbjct:    6 LLPLLRACMNSKSLKQGKLIHQKVVTLGLQNDIFLCKNLINLYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVLKACGGLYKYVLGKMIHTCLVKTGLMMDIVVGSSLVGMYAKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKEALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEVFEQMPKKTVVAWNSMISGYGLKGDSISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEG-----KFVHGYTIRNRIQSDVFINSSLMDLYFKCGKVELAENIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVEPDAITFTSVLTACSQLAALEKGEEIHNLIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSV 466          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            + SLKQGKLIHQK++TLGLQND  LCK LIN Y SCH  D AK VF ++ENP  ISLWNG+M G+TKN+M+VEALELFE LL YPY+ PDSYTYPSV KACG L +   GKMIH  LIKTG + DIVV SSLV MY KCN F+ AI LF+EMPE+DVACWNTVISCYYQ G  + A+E F  MR  GF PNSVT+TT ISSCARL DL RGM+IH+ELI    +LDSF++SALVDMYGKCG L+MA E+FEQ+P K VVAWNSMI+ Y + GD ISCIQ F+RM  EG  PTLTT SS+++ CSRSA+LL GKF+H + IRN I+ D+++ SSL+DLYF  G V  A+ +F+ +PK+  VSWNVMISGYV  G  F AL ++ +M+++ V  +AIT TS+L+ACSQLAALEKGKEIH  +I+ + + NE++MGALLDMYAKCGAVDEA +VF  LP RD VSWTSMITAYGSHG A  AL+LF EM QSN KPD V  LA+LSAC H GLVDEGC++FNQMI  YGI PR+EHYSCLIDLLGRAGRL+EAYEILQ+  EIR+DV+LLSTLFSACRLHRN+DLG +IAR LI+K+PDD STYI+LSN YAS  KWDEV+ VR KMKELGL+KNPGCSWIEIN+KI PFFV D SH   E+
Sbjct:   16 SKSLKQGKLIHQKVVTLGLQNDIFLCKTLINQYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVFKACGGLHRYVLGKMIHTCLIKTGLMMDIVVGSSLVGMYGKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKDALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEIFEQMPKKTVVAWNSMISGYGLKGDIISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEGKFVHGYTIRNRIQPDVFVNSSLMDLYFKCGKVELAEKIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVESDAITFTSVLTACSQLAALEKGKEIHNLIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSVFKCLPKRDLVSWTSMITAYGSHGHAYGALELFAEMLQSNVKPDRVAFLAILSACGHAGLVDEGCYYFNQMINVYGIIPRVEHYSCLIDLLGRAGRLHEAYEILQQNPEIRDDVELLSTLFSACRLHRNIDLGAEIARTLIDKDPDDSSTYILLSNMYASAHKWDEVRVVRSKMKELGLKKNPGCSWIEINQKILPFFVEDNSHLHLEL 674          

Query:  292 VLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISCYYQDGQAQKAMELFEKMRNSGF-TPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQ 1668
            +L+AC     +  GK+IH  ++  G  +DI +  +L+  Y  C+++D A  +FD M    +++ WN +++ Y ++    +A+ELFEK+ +  +  P+S T  +V  +C  L     G  IH  LIK  L++D  V S+LV MYGKC   + A  +F ++P K+V  WN++I+ Y  +G+    +++F  M R G  P   T ++ + +C+R   L  G  IH  +I +    D +I S+L+D+Y   G +  A  +FE+MPK   V+WN MISGY   GD    + ++  M   GV+P   T++S++  CS+ A L +GK +H   I +  + +  +  +L+D+Y KCG V+ A  +F  +P    VSW  MI+ Y + G+  EAL LF EM++S  + D +T  +VL+ACS +  +++G    N +I    +         L+D+  + G ++EA+ + +
Sbjct:    9 LLRACMNSKSLKQGKLIHQKVVTLGLQNDIFLCKTLINQYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVFKACGGLHRYVLGKMIHTCLIKTGLMMDIVVGSSLVGMYGKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKDALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEIFEQMPKKTVVAWNSMISGYGLKGDIISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEGKFVHGYTIRNRIQPDVFVNSSLMDLYFKCGKVELAEKIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVESDAITFTSVLTACSQLAALEKGKEIHN-LIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSVFK 468          

Query:  586 LTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGDSISCIQFFRR-MNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQ---------------------------------RTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYI-MLSNTYASVKKWDEVKKV 1863
            L  ++ +C     L++G  IH++++   L  D F+   L++ Y  C   D AK VF+ +     +  WN ++A Y+     +  ++ F + ++     P   T+ S+  AC    + + GK IH  +I+  +  DI + SSL+ +Y    +   A  +F +MP+ +   WN +IS Y + G++  AL  +  M+  G  PN++T+T+ +S+C++L  L +G EIH  +I+S F  +  +  AL+DMY KCG ++ A+ +F ++P +  V+W SMI+ YG  G  +  ++LF  M     KP   TL +++  CS    + EG       I N  I+P +   S L+DL  + G++  A +I +                                 R S +  D    +++ +AC     L+ G +I  L+IEK  D++   +  L + YA     DE   V
Sbjct:    6 LLPLLRACMNSKSLKQGKLIHQKVVTLGLQNDIFLCKTLINQYLSCHLYDHAKCVFDNMENPCEISLWNGLMAGYTKNYMYVEALELFEKLLHYPYLKPDSYTYPSVFKACGGLHRYVLGKMIHTCLIKTGLMMDIVVGSSLVGMYGKCNAFEKAIWLFNEMPEKDVACWNTVISCYYQSGNFKDALEYFGLMRRFGFEPNSVTITTAISSCARLLDLNRGMEIHEELINSGFLLDSFISSALVDMYGKCGHLEMAIEIFEQMPKKTVVAWNSMISGYGLKGDIISCIQLFKRMYNEGVKPTLTTLSSLIMVCSRSARLLEGKFVHGYTIRN-RIQPDVFVNSSLMDLYFKCGKVELAEKIFKLIPKSKVVSWNVMISGYVAEGKLFEALGLFSEMRKSYVESDAITFTSVLTACSQLAALEKGKEIHNLIIEKKLDNNEVVMGALLDMYAKCGAVDEAFSV 466          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSH 1965
            + SLKQGK++HQK++TLGLQND  +CKNLI+ Y SC+  D AK VF  IENP  ISL NG+M G+T+N M+ EAL LF+ L+ YP + PDSYTYPSVLKACG L +V  G+MIH  L+K G + DIVV SSLV MYAKCN F+CA++LFDEMP++DVACWNTVISCYYQ G+ ++A+  F  MR  GF P+SVT+TT ISSCARL DL+RG +IHKEL+     +DSFV++ALVDMYGKCG L+MA EVFEQ+P K VVAWNSMI  Y   GD ISCIQ F+RM  EG  PTLTT +S L+ACS+SAQLL GKF+H ++IRN I+ DI++ SSL+DLYF  G V SA+ +F+ MPKT TVSWNVMISGYV  G  F AL ++ +M ++ V P+AIT TS+L+ACSQLAALEKG+EIH  +++     NE++MGALLDMYAKCGAV+EA  VF  LP RD VSWTSMITAYGSHG+  EAL+LF EM QSN KPD VT LA+LSACSH GLVD+G + FNQMI  YGI PRIEHYSCLI LLGRAGRL+EAYEILQ   EI +D  LLSTLFSACRLH+NLDLGV+IA  LI+K+PDD STYI+LSN YAS  KWDEV+ VR KMK+LGL+KNPGCSWIEIN+KI PFFV D SH
Sbjct:   16 SKSLKQGKVLHQKVVTLGLQNDVYVCKNLISLYVSCNLFDYAKNVFDVIENPFEISLCNGLMAGYTRNCMYDEALGLFDKLMCYPCLKPDSYTYPSVLKACGGLRRVVLGQMIHTCLVKEGLMVDIVVGSSLVGMYAKCNEFECAVKLFDEMPDKDVACWNTVISCYYQSGKFEEALRYFGMMRRFGFEPDSVTITTAISSCARLLDLDRGREIHKELVNSGFRMDSFVSAALVDMYGKCGQLEMAIEVFEQMPNKTVVAWNSMINGYGFKGDGISCIQLFKRMYSEGVKPTLTTLTSTLMACSQSAQLLEGKFVHGYIIRNRIQPDIFLNSSLMDLYFKCGKVESAETIFKLMPKTTTVSWNVMISGYVTEGKLFDALRLFGEMSKSFVEPDAITFTSVLAACSQLAALEKGREIHNLIVERNLGNNEVVMGALLDMYAKCGAVEEAFGVFKCLPERDLVSWTSMITAYGSHGRVYEALELFAEMLQSNVKPDRVTFLAILSACSHAGLVDDGLYHFNQMINVYGIIPRIEHYSCLITLLGRAGRLHEAYEILQSNPEISDDFQLLSTLFSACRLHKNLDLGVEIAENLIDKDPDDSSTYIILSNMYASFGKWDEVRMVRSKMKDLGLKKNPGCSWIEINEKIVPFFVEDNSH 669          

Query:  898 ILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVS-WNVMISGYVKVGDYFGALAIYDD-MKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQR 1671
            +L A   S  L  GK +H  ++   ++ D+Y+  +LI LY        AKNVF+ +     +S  N +++GY +   Y  AL ++D  M    ++P++ T  S+L AC  L  +  G+ IH  ++      + ++  +L+ MYAKC   + A+ +F+ +P++D   W ++I+ Y   G+  EAL+ FG M++   +PD VT+   +S+C+ +  +D G     +++ N G +      + L+D+ G+ G+L  A E+ ++
Sbjct:    9 LLRASVNSKSLKQGKVLHQKVVTLGLQNDVYVCKNLISLYVSCNLFDYAKNVFDVIENPFEISLCNGLMAGYTRNCMYDEALGLFDKLMCYPCLKPDSYTYPSVLKACGGLRRVVLGQMIHTCLVKEGLMVDIVVGSSLVGMYAKCNEFECAVKLFDEMPDKDVACWNTVISCYYQSGKFEEALRYFGMMRRFGFEPDSVTITTAISSCARLLDLDRGREIHKELV-NSGFRMDSFVSAALVDMYGKCGQLEMAIEVFEQ 267          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL++ KL+HQ++LTLGL+ D  LCK+LIN YF+C    SA+ VF++ +  S + +WN +M+G++KN MF + LE+F+ LL      PDS+T+P+V+KA GALG+   G+MIH  ++K+G+V D+VVASSLV MYAK N+F+ ++++FDEMPERDVA WNTVISC+YQ G+A+KA+ELF +M +SGF PNSV+LT  IS+C+RL  LERG +IH++ +K    LD +V SALVDMYGKC CL++A+EVF+++P K++VAWNSMI  Y   GDS SC++   RM  EGT P+ TT +SIL+ACSRS  LLHGKFIH ++IR+++ ADIY+  SLIDLYF  G  + A+ VF K  K    SWNVMIS Y+ VG++F A+ +YD M   GV+P+ +T TS+L ACSQLAALEKGK+IH ++ +S  ET+E+++ ALLDMY+KCG   EA  +FN +P +D VSWT MI+AYGSHGQ  EAL  F EMQ+   KPDGVTLLAVLSAC H GL+DEG  FF+QM + YGI+P IEHYSC+ID+LGRAGRL EAYEI+Q+T E  ++ +LLSTLFSAC LH    LG +IARLL+E  PDD STY++L N YAS + WD  ++VRLKMKE+GLRK PGCSWIE++ K+  FF  D+SH ++E
Sbjct:   19 SLRRIKLVHQRILTLGLRRDVVLCKSLINVYFTCKDHCSARHVFENFDIRSDVYIWNSLMSGYSKNSMFHDTLEVFKRLLNCSICVPDSFTFPNVIKAYGALGREFLGRMIHTLVVKSGYVCDVVVASSLVGMYAKFNLFENSLQVFDEMPERDVASWNTVISCFYQSGEAEKALELFGRMESSGFEPNSVSLTVAISACSRLLWLERGKEIHRKCVKKGFELDEYVNSALVDMYGKCDCLEVAREVFQKMPRKSLVAWNSMIKGYVAKGDSKSCVEILNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFIHGYVIRSVVNADIYVNCSLIDLYFKCGEANLAETVFSKTQKDVAESWNVMISSYISVGNWFKAVEVYDQMVSVGVKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQMRSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTPETSDNAELLSTLFSACCLHLEHSLGDRIARLLVENYPDDASTYMVLFNLYASGESWDAARRVRLKMKEMGLRKKPGCSWIEMSDKVCHFFAEDRSHLRAE 674          

Query:    4 NNSLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVT--SALVDMYGKCGCLDMAKEVFEQIP 765
            + +L  GK IH  ++   +  D  +  +LI+ YF C   + A+ VF   +   + S WN +++ +     + +A+E+++ ++    + PD  T+ SVL AC  L  +  GK IH  + ++   +D ++ S+L+ MY+KC     A R+F+ +P++DV  W  +IS Y   GQ ++A+  F++M+  G  P+ VTL  V+S+C     ++ G+K   ++ + +  ++  +   S ++D+ G+ G L  A E+ +Q P
Sbjct:  322 SRNLLHGKFIHGYVIRSVVNADIYVNCSLIDLYFKCGEANLAETVFSKTQKDVAES-WNVMISSYISVGNWFKAVEVYDQMVSVG-VKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQM-RSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTP 574          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            SL+Q KL+HQ++LT+GL++D  LCK+LIN YF+C    SA+LVF++I+  S + +WN +++G++KN MF + L++F+ LL  P   PDS+TYP+V+KA GALG+   G+MIH  ++K+G V D+VVASSLV MYAK N+F+ ++++FDEMPERDVA WNTVIS +YQ G A+KA+ELF +M  S F PNSV++T  IS+C+RL  LERG +IH++ +K +  LD +V SALVDMYG+C  L+MA+EVF+Q+  K++VAWNSMI  Y   GDS SC++   RM  EGT P+ TT +SIL+ACSRS  LLHGKF+H ++IR++++ADIYI  SLIDLYF  G V  A+ VF K  K    SWNVMISGYV VG++F A+ +YD M   GV+P+ +T TS+LS CSQLAALEKGK+IH ++ +S  ET+E+++ ALLDMY+KCG V EA  +FN +P +D VSWT MI+AYGSHGQ  EAL  F EMQ+   KPDGVT LAVLSAC H GL+DEG  +F+QM + YGI+  IE YSCLID+LGRAGRL EAY ILQ+  E R++ +LLSTLF AC LHR+  LG  IA+LL+EK PDD STY +L N YAS + WD  K+VRLKMKE+G+RK PGCSWIE+N+K+  FF  D+SHPQ+E
Sbjct:   18 SLRQAKLVHQRILTVGLRSDVVLCKSLINVYFACKDHCSARLVFENIDIRSDVYIWNSLVSGYSKNSMFHDTLKVFKRLLNCPICVPDSFTYPNVIKAYGALGREFLGRMIHTVVVKSGHVCDVVVASSLVGMYAKFNLFEDSVQVFDEMPERDVASWNTVISSFYQRGDAEKALELFGRMERSDFEPNSVSITVAISACSRLLCLERGKEIHRKYLKKEFELDEYVNSALVDMYGRCDFLEMAREVFQQMRRKSLVAWNSMIRGYVARGDSKSCVELLNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFVHGYVIRSVVDADIYINCSLIDLYFKCGEVKLAETVFLKTQKDVVESWNVMISGYVSVGNWFKAVDVYDQMVSVGVQPDIVTFTSVLSTCSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNVKEASRIFNSIPKKDVVSWTVMISAYGSHGQPREALYHFDEMQKFGVKPDGVTFLAVLSACGHAGLIDEGVKYFSQMRSKYGIEASIEQYSCLIDILGRAGRLLEAYGILQQKPETRDNAELLSTLFCACCLHRDHLLGYTIAKLLVEKYPDDASTYTVLFNLYASGESWDAAKRVRLKMKEVGMRKKPGCSWIEMNEKVCHFFAEDRSHPQAE 673          

Query:  289 SVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISCYYQDGQAQKAMELFEKMRNSGF-TPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLH 1734
            S+L+ C     +   K++H  ++  G  SD+V+  SL+ +Y  C     A  +F+ +  R DV  WN+++S Y ++      +++F+++ N     P+S T   VI +   L     G  IH  ++K   V D  V S+LV MY K    + + +VF+++P ++V +WN++I+++   GD+   ++ F RM R    P   + +  + ACSR   L  GK IH   ++   E D Y+ S+L+D+Y     +  A+ VF++M + + V+WN MI GYV  GD    + + + M   G RP+  T+TSIL ACS+   L  GK +H  VI S  + +  +  +L+D+Y KCG V  A  VF +       SW  MI+ Y S G   +A+ ++ +M     +PD VT  +VLS CS +  +++G    +  I+   ++      S L+D+  + G + EA  I    S  ++DV   + + SA   H
Sbjct:    8 SLLRECTNTKSLRQAKLVHQRILTVGLRSDVVLCKSLINVYFACKDHCSARLVFENIDIRSDVYIWNSLVSGYSKNSMFHDTLKVFKRLLNCPICVPDSFTYPNVIKAYGALGREFLGRMIHTVVVKSGHVCDVVVASSLVGMYAKFNLFEDSVQVFDEMPERDVASWNTVISSFYQRGDAEKALELFGRMERSDFEPNSVSITVAISACSRLLCLERGKEIHRKYLKKEFELDEYVNSALVDMYGRCDFLEMAREVFQQMRRKSLVAWNSMIRGYVARGDSKSCVELLNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFVHGYVIRSVVDADIYINCSLIDLYFKCGEVKLAETVFLKTQKDVVESWNVMISGYVSVGNWFKAVDVYDQMVSVGVQPDIVTFTSVLSTCSQLAALEKGKQ-IHLSISESRLETDELLLSALLDMYSKCGNVKEASRIF--NSIPKKDVVSWTVMISAYGSH 488          

Query:  577 SVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIK-NVVAWNSMIAAYSVTGDSISCIQFFRR-MNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIE---HYSC-LIDLLGRAGRLNEAYEILQRTSE 1680
            S  L +++  C     L +   +H+ ++   L  D  +  +L+++Y  C     A+ VFE I I+ +V  WNS+++ YS        ++ F+R +N     P   T+ +++ A     +   G+ IH  ++++    D+ + SSL+ +Y        +  VF++MP+ +  SWN +IS + + GD   AL ++  M+ +   PN++++T  +SACS+L  LE+GKEIHR  +  EFE +E +  AL+DMY +C  ++ A  VF ++  +  V+W SMI  Y + G +   ++L   M     +P   TL ++L ACS    +  G     + +  Y I+  ++   + +C LIDL  + G +  A  +  +T +
Sbjct:    3 SSKLLSLLRECTNTKSLRQAKLVHQRILTVGLRSDVVLCKSLINVYFACKDHCSARLVFENIDIRSDVYIWNSLVSGYSKNSMFHDTLKVFKRLLNCPICVPDSFTYPNVIKAYGALGREFLGRMIHTVVVKSGHVCDVVVASSLVGMYAKFNLFEDSVQVFDEMPERDVASWNTVISSFYQRGDAEKALELFGRMERSDFEPNSVSITVAISACSRLLCLERGKEIHRKYLKKEFELDEYVNSALVDMYGRCDFLEMAREVFQQMRRKSLVAWNSMIRGYVARGDSKSCVELLNRMIIEGTRPSQTTLTSILMACSRSRNLLHG-----KFVHGYVIRSVVDADIYINCSLIDLYFKCGEVKLAETVFLKTQK 371          

Query:  187 MTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGR 1632
            M  +TKN M+ EALELF+ LL+YPY+ PDS+TYPSVLKACG LG+  +G+MIH HLIK+GFV DIVVASSLV ++AKCN+F  AI+LFDEMPERDVACWNTVISCYYQDG+A+KA+E+F KMR+SGF PNSVTLTTVISSCARL DLERG +IH+E++++ +VLD FV SALVDMYGK GCLD+AK++FEQ+P K +VAWNS+IA YS   DS  CI+ F RMN EGT PT+TT SSILLACSR+A L HG+FIH + +RN ++ DI++ S LI+LYF  G V SA+N+F  +PK N V WNVMISGYV +GDY  AL +YD+MK A V+P+A+T +SILSACSQLAALEKGKEIH  +  ++ ETNEI+MGALLDMYAKCGAVDEAL+VFN+LP RD +SWTS+I+AYGSHGQALEAL+LF E+QQS A PD VT LAVLSACSH GLVD+G ++FNQMITNYGIKP +EHYSCLIDLLGR
Sbjct:    1 MAAYTKNCMYTEALELFDRLLQYPYLQPDSFTYPSVLKACGGLGRYDYGRMIHTHLIKSGFVFDIVVASSLVSLHAKCNLFGYAIQLFDEMPERDVACWNTVISCYYQDGKAEKALEMFGKMRDSGFEPNSVTLTTVISSCARLLDLERGKEIHREVMQNGMVLDGFVGSALVDMYGKFGCLDLAKDIFEQMPKKTLVAWNSLIAGYSSAADSKECIELFWRMNMEGTKPTVTTLSSILLACSRAAHLQHGRFIHGYAVRNRVQLDIFVSSGLIELYFKCGKVQSAENIFYMLPKANVVLWNVMISGYVTIGDYVKALDMYDEMKIASVKPDAVTFSSILSACSQLAALEKGKEIHNCITKNDLETNEIVMGALLDMYAKCGAVDEALSVFNKLPERDLLSWTSIISAYGSHGQALEALRLFEELQQSKASPDAVTFLAVLSACSHAGLVDKGYYYFNQMITNYGIKPGLEHYSCLIDLLGR 482          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNI-IEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTN 1077
            L++GK IH++++  G+  D  +   L++ Y      D AK +F+ +   + ++ WN ++ G++      E +ELF   +      P   T  S+L AC     +  G+ IH + ++     DI V+S L+ +Y KC     A  +F  +P+ +V  WN +IS Y   G   KA++++++M+ +   P++VT ++++S+C++L  LE+G +IH  + K+ L  +  V  AL+DMY KCG +D A  VF ++P +++++W S+I+AY   G ++  ++ F  + +   SP   TF ++L ACS +  +  G +    MI N  I+  +  YS LIDL    G +        ++P  N
Sbjct:  147 LERGKEIHREVMQNGMVLDGFVGSALVDMYGKFGCLDLAKDIFEQMPKKTLVA-WNSLIAGYSSAADSKECIELFWR-MNMEGTKPTVTTLSSILLACSRAAHLQHGRFIHGYAVRNRVQLDIFVSSGLIELYFKCGKVQSAENIFYMLPKANVVLWNVMISGYVTIGDYVKALDMYDEMKIASVKPDAVTFSSILSACSQLAALEKGKEIHNCITKNDLETNEIVMGALLDMYAKCGAVDEALSVFNKLPERDLLSWTSIISAYGSHGQALEALRLFEELQQSKASPDAVTFLAVLSACSHAGLVDKGYYYFNQMITNYGIKPGLEHYSCLIDLL---GRIQEQSQELNEIPCPN 497          

Query:  289 SVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DVACWNTVISC------YYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSEM 1980
            S+LK C     +  GK+IH  ++  G  ++I +  SL+ +Y  C++F  A  +F  +    D+  WN +++       + +  + +KA+ELFE+M+ SGF P+SVTLTTVISSCARL DLERG +IH EL++    LD FV+SALVDMYGKCGCL+MAKEVFEQI  KNVV+WNSMIA YS+ GDS SCI+ FRRM+ EG  PTLTT SSIL+ACSRS  L  GKFIH ++IRN +EADI++ SSLIDLYF  G++ SA+NVF+ MPKTN VSWNVMISGYVKVG Y  AL I+ DM++AGV+P+AIT TS+L ACSQLA LEKGKEIH  +I+S+ E NE++   +    AK                 D V++ ++++A                                   CSH GLVDEGC++FNQMI  YG KP +EHYSCLIDLLGR GRL EAYEILQRT +IREDV LLSTLFSAC LH+ LDLG +I RLLIEK+PDD STYI+LSN YASVKKWDEV+KVRLK+KELGL+KNPGCSWIE+ K+IHPF V DKSHPQ++M
Sbjct:    8 SLLKTCIDSKYLKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEPEKALELFEEMKVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEVLFEKMQQSDAK----------------PDKVTFLAILSA-----------------------------------CSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPDIREDVGLLSTLFSACHLHKKLDLGEQIGRLLIEKDPDDPSTYIILSNMYASVKKWDEVRKVRLKIKELGLKKNPGCSWIEVGKRIHPFVVEDKSHPQADM 527          

Query:   13 LKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVE------ALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKG-KEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPN 1374
            LKQGKLIHQK+++LGLQN+  LCK+LIN YFSCH   SAKLVFQ+IENP  I+LWNG+M   TKN +F+E      ALELFE + +     PDS T  +V+ +C  L  +  GK IH  L+++GF  D  V+S+LV MY KC   + A  +F+++  ++V  WN++I+ Y   G ++  +ELF +M   G  P   TL++++ +C+R  +L+ G  IH  +I++++  D FV S+L+D+Y KCG +  A+ VF+ +P  NVV+WN MI+ Y   G  +  +  F  M + G  P   TF+S+L ACS+ A L  GK IH F+I + +E +                    + +FEK                               M+++  +P+ +T  +ILSACS    +++G    ++ + +  F+        L+D+  + G + EA  +  R P+
Sbjct:   19 LKQGKLIHQKIVSLGLQNNITLCKSLINLYFSCHLFQSAKLVFQTIENPLDITLWNGLMAACTKNFIFIEGLEPEKALELFEEM-KVSGFKPDSVTLTTVISSCARLLDLERGKEIHMELVRSGFALDGFVSSALVDMYGKCGCLEMAKEVFEQIQRKNVVSWNSMIAGYSLKGDSKSCIELFRRMDEEGIRPTLTTLSSILMACSRSVNLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVSWNVMISGYVKVGSYLEALVIFTDMRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEIN--------------------EVLFEK-------------------------------MQQSDAKPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHYSCLIDLLGRVGRLREAYEILQRTPD 427          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTGFTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKD---QLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIP 765
            +L+ GK IH  ++   ++ D  +  +LI+ YF C    SA+ VFQ++   + +S WN +++G+ K   ++EAL +F   +R   + PD+ T+ SVL AC  L  +  GK IHN +I++    + V                    LF++M + D                                 P+ VT   ++S+C+    ++ G     ++I +   +  ++ +  S L+D+ G+ G L  A E+ ++ P
Sbjct:  227 NLQLGKFIHGYIIRNRVEADIFVNSSLIDLYFKCGNIGSAENVFQNMPKTNVVS-WNVMISGYVKVGSYLEALVIFTD-MRKAGVKPDAITFTSVLPACSQLAVLEKGKEIHNFIIESKLEINEV--------------------LFEKMQQSDA-------------------------------KPDKVTFLAILSACSHAGLVDEGCYYFNQMIAEYGFKPAVEHY--SCLIDLLGRVGRLREAYEILQRTP 426          

Query:  334 KMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPER-DV--------ACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIMMGALLDMYAKCGAVDEALNVFNRLPNRDPVSWTSMITAYGSHGQALEALKLFGEMQQSNAKPDGVTLLAVLSACSHVGLVDEGCHFFNQMITNYGIKPRIEHYSCLIDLLGRAGRLNEAYEILQRTSEIREDVDLLSTLFSACRLHRNLDLGVKIARLLIEKNPDDHSTYIMLSNTYASVKKWDEVKKVRLKMKELGLRKNPGCSWIEINKKIHPFFVGDKSHPQSE 1977
            K++H  ++  G   D+V+  SL+ +Y  C     A  +F+    R DV        A WNTVISC+YQ G+A+KA+ELF +M +SGF PNSV+LT  IS+C+RL  LERG +IH++ +K    LD +V SALVDMYGKC CL++A+EVF+++P K++VAWNSMI  Y   GDS SC++   RM  EGT P+ TT +SIL+ACSRS  LLHGKFIHA +                           A+ VF K  K    SWNVMIS Y+ VG++F A+ +YD M   GV+P+ +T TS+L ACSQLAALEKGK+IH ++ +S  ET+E+++ ALLDMY+KCG   EA  +FN +P +D VSWT MI+AYGSHGQ  EAL  F EMQ+   KPDGVTLLAVLSAC H GL+DEG  FF+QM + YGI+P IEHYSC+ID+LGRAGRL EAYEI+Q+T E  ++ +LLSTLFSAC LH    LG +IARLL+E  PDD STY++L N YAS + WD  ++VRLKMKE+GLRK PGCSWIE++ K+  FF  D+SH ++E
Sbjct:   51 KLVHQRILTLGLRRDVVLCKSLINVYFTCKDHCSARHVFENFDIRSDVYIWNSLMSASWNTVISCFYQSGEAEKALELFGRMESSGFEPNSVSLTVAISACSRLLWLERGKEIHRKCVKKGFELDEYVNSALVDMYGKCDCLEVAREVFQKMPRKSLVAWNSMIKGYVAKGDSKSCVEILNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFIHANL---------------------------AETVFSKTQKDVAESWNVMISSYISVGNWFKAVEVYDQMVSVGVKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQMRSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTPETSDNAELLSTLFSACCLHLEHSLGDRIARLLVENYPDDASTYMVLFNLYASGESWDAARRVRLKMKEMGLRKKPGCSWIEMSDKVCHFFAEDRSHLRAE 580          

Query:   10 SLKQGKLIHQKMLTLGLQNDPALCKNLINFYFSCHFCDSAKLVFQSIENPSSISLWNGVMTG--------FTKNHMFVEALELFESLLRYPYIGPDSYTYPSVLKACGALGQVGFGKMIHNHLIKTGFVSDIVVASSLVCMYAKCNVFDCAIRLFDEMPERDVACWNTVISCYYQDGQAQKAMELFEKMRNSGFTPNSVTLTTVISSCARLFDLERGMKIHKELIKDQLVLDSFVTSALVDMYGKCGCLDMAKEVFEQIPIKNVVAWNSMIAAYSVTGDSISCIQFFRRMNREGTSPTLTTFSSILLACSRSAQLLHGKFIHAFMIRNIIEADIYIYSSLIDLYFVSGSVSSAKNVFEKMPKTNTVSWNVMISGYVKVGDYFGALAIYDDMKEAGVRPNAITVTSILSACSQLAALEKGKEIHRTVIDSEFETNEIM--MGALLDMYAKCGAVDEALNVFNRLP 1371
            SL++ KL+HQ++LTLGL+ D  LCK+LIN YF+C    SA+ VF++ +  S + +WN +M+         F ++    +ALELF  +    +  P+S +    + AC  L  +  GK IH   +K GF  D  V S+LV MY KC+  + A  +F +MP + +  WN++I  Y   G ++  +E+  +M   G  P+  TLT+++ +C+R  +L  G  IH  L                           A+ VF +       +WN MI++Y   G+    ++ + +M   G  P + TF+S+L ACS+ A L  GK IH  +  + +E D  + S+L+D+Y   G+   A  +F  +PK + VSW VMIS Y   G    AL  +D+M++ G++P+ +T+ ++LSAC     +++G +   + + S++    I+     ++D+  + G + EA  +  + P
Sbjct:   46 SLRRIKLVHQRILTLGLRRDVVLCKSLINVYFTCKDHCSARHVFENFDIRSDVYIWNSLMSASWNTVISCFYQSGEAEKALELFGRMESSGF-EPNSVSLTVAISACSRLLWLERGKEIHRKCVKKGFELDEYVNSALVDMYGKCDCLEVAREVFQKMPRKSLVAWNSMIKGYVAKGDSKSCVEILNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFIHANL---------------------------AETVFSKTQKDVAESWNVMISSYISVGNWFKAVEVYDQMVSVGVKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFF-SQMRSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTP 480