ppa017522m, ppa017522m (mRNA) Prunus persica

Query:   94 VSITIHEEASP-REERLNKLR---EEAPPIQAEKVK-PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYD---ELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKK---------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHS 1371
            + I + + AS  RE+R   +    E++   Q  + K  +I KVP MLR  K F   +EP V ++GP+HH +      AE +K  +   F+ +S+Q    L  K+   I+ELR CY++ ATKKY+DE LAWM+ VDGCS L FI  Y    +L++  IK    AF + D+F                     +E  + I++F+G  +    PA ++                 E +P HLL+LLR  +L  ++  +                EL+A+GI FKP++  SLR I F S+ L  G L LP+I +DDST+ +F+NLIAYEMCP+  N+  VTSYICFLDSLID P+DVK LR++ +LRNFLG+D+EVA+LFNEI TDLVP++D Y  VK +I+ HY+   +  +A+  H HFSSPWT +AF           +QT Y+V   H+
Sbjct:   47 IDIVVEDNASSSREKRFKSVMGGPEDSKRSQLSETKWARIPKVPHMLRGTKDFKILFEPRVVSVGPYHHHK-HDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDEDLAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGF--EEGMQMIEQFIGSAAETDPPAVKSDN---------------EEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILL-GFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRHN 476          

Query:  835 EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRV----MAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            +EL A+GI  K S    LR I F S  +    L +P I +D+ST+  F+NLIAYEM  D  +DF   SY+ FLDSLID  DDVK L+   IL+N LG  EEVAQ FN +  +L  N   Y  V+ +I  H  N  N      M Q    +F SPWT IA+           VQT +SV
Sbjct:   35 KELMAAGIRIKRSPTRHLRDISFRSNGIT-ACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDF--ISYLRFLDSLIDHADDVKELQSIGILQNNLGTHEEVAQFFNTVSANLESNFHAYKDVRVRIRKHLKNHYNSKLKMWMTQCLDTYFGSPWTIIAWVGAALALFFTAVQTYFSV 209          

Query:  688 PAAAPADQNGQNPEAEE-----QRSQPGQEVEAEPTHL----LELLRTTMLPYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPN----NDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            P + P   N ++          +R+  G E    PTH     LE+     +       +EL  +GI  K S    LR I F S  +    L +P I +D+ST+  F+NLIAYEM  D  +DF   SY+ FLDSLID  DDVK L+   IL+N LG  +EVAQ FN +  +L  N     D+   ++  ++ HY++     M Q    +F SPWT IA+           VQT +S
Sbjct:   18 PKSKPQSPNNESKPCHHLLDLFRRNFLGDERSGSPTHPENENLEVRDVKEVMASFRNVKELMDAGIRIKRSPTRHLRDISFRSNGIT-ACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDF--ISYLRFLDSLIDHADDVKELQSIGILQNNLGTHDEVAQFFNTVSANLESNFHAYKDVRVKIRKHLQSHYNSKLTMWMTQCLDTYFGSPWTIIAWVGAALALFLTFVQTYFS 249          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRD---SKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVG-RNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML--------------------PYESEKK-----EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPN-NDIYSS-----VKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHS 1371
            I +VP  LR+  K    + P + ++GPFH+   P   + E+ K++     +      K   A+ L   E    + R+CY        D      M+ +DGC  LE +  Y+  E  +        V+  IF                   +   + K + E +     P          +P    +  +     E E  H+LE+ R+T L                    P   E++      EL+ +G+  K  E   L  I F +     G+L +P + +DD+T   F+N +AYE C D    F  T+Y+ F DSLI+   DV  L K  I+ + LG+D++VA LFN++G ++V + ++ Y S     V +  + +Y +          H++FS+PWT  +             QT Y+V GY+S
Sbjct:   42 IYRVPRNLREVHK--NAFVPKIISIGPFHYGD-PGLRFMEEHKVRYLLRLLGSRTPEKGGQAEELMSQELE-QKTRQCYT--GAFDIDSNDFVQMMVIDGCFVLELLRLYNRFEREKN-------VDDPIFTIRWMLRTLQRDLLKLENQLPFFVLKKLFELISLAEDPPLIDLVLTFFDPLLPRKNIEGNLNPEGEFDHMLEVFRSTFLSSVNQDITSGCEQLKISVNVPLVQERQLIHSVTELEKAGVKLKKREDCDLLDINFQA-----GVLKIPPLYIDDNTAVLFLNFVAYEQCEDTKPFF--TNYLMFFDSLINSSADVGILHKNGIINHVLGSDQDVADLFNKLGREVVYDLDECYLSQQIKRVNNYCKTYYASKWRVWFTNLKHDYFSNPWTFFSLLAAIALLLLTTAQTYYTVYGYYS 448          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANF-----------VRDSKQNDADLLKKVE-DNINELRKCYDEEATKKY------DDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKE--------------------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPN-NDIYSS-----VKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHSSK 1377
            + +VP  +R  +K    + P + ++GPFH+ + P     E+ K++                V DS Q    ++K +  +++ E  +  +++  + Y      D + L  M+ +DGC  LE +  Y + +N +   D +      +                       EL + +D+      P          +P    +  +       E  H+L++ R+T L   +E+ +                          ELQ +G+ FK  E   L  I F       G+L +P + +DD+T P F+NL+AYE C      F  T++  F DSLI+   DV  L K  I+ + LG+D++VA LFN++G ++V + ++ Y S     V D  + ++ +  +        ++FSSPWT ++             QT Y+V  Y+  K
Sbjct:   53 VYRVPKSMRGIQK--NAFLPKIISIGPFHN-KDPGLRIMEEHKMRYLLRLLESGPRENGERVEDSAQQVPQVVKAIRLEDLAESMRMLEQKTRENYSEDLQIDSDELIQMMVIDGCFVLELLRLYFKFDNEEEVEDPIFTTRWMLRTLQRDLLKLENQLPFFVLEKLYELIRLVDD------PPLVDLVVTFFDPLLPRKNIKGKLNPNEEFDHMLDVFRSTFLSSINERTKPAGWKQLQKLDNIPLVEERQLIHCVTELQEAGVRFKMREDLDLLDISFKD-----GMLKIPPLYIDDNTVPLFLNLVAYEQCDQDAKPF-FTNFCMFFDSLINSHTDVGILHKNGIINHVLGSDKDVANLFNKLGREIVYDLDECYLSQQMMDVNDYCKQYFASKWHVWFTNLIRDYFSSPWTFLSLLAAIALLLLTTAQTFYAVYAYYFPK 481          

Query:   91 EVSITIHEEASPREERLNKLREEAPPI---QAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDA---DLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKK-------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLV--PNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGY 1365
            +V + I E    R  R+ +   E P +    A +    I +VP  L +     + Y+P + ++GP+H    P  +  E+ K     + +  ++++     D L+ ++    E R+CY E       D FL  ML +DGC  ++F  K  ++  F+     V+      F                   +    K   +E    + P+ A       N   +       +    +  H L+LLR + +P E E                +L+ +GI  K  + +S  ++ F +     G++ +P + +DD     F N +A+E+C   H D    +T+Y   LD LI+   DV HL ++ I  N+ G D  VA+  N +G D+   P+N   S + + + ++Y N  +  +A   + +F +PW+ I+           IVQT Y+V  Y
Sbjct:    7 DVVVRIWEVNKERLARMQQKISEEPRLLRKSAGRSSCCIFRVPRTLVEINS--RSYQPHIISIGPYHRGE-PHLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMEARECYSEIIHLDTHD-FLE-MLVLDGCFIIDFFRKIGKMHPFEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTKMPGEE----SGPSLASLVLGFFNNTLQRPDEILQKHCNLKGKHFLDLLRLSFIPEEQELGTLDHRPTHLIQCVSKLRKAGIKLKSGKADSFLTVKFRN-----GVMEMPPVTIDDFLTCFFQNCVAFELC---HKDCTKHITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTVYPY 437          

Query:  112 EEASPREERLNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVE----HDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKE------------ELQASGIHFK--PSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIY-SSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            E A+  + RL++L   +      +V  K++KV           + Y P V ++GP HH         E+ KL+   NF+  +++   + ++ +       R CY E        EF+  M+ VDGC  +E I  +        K D   F +    +D+                       E+ +  + +      +        Q PEA++ +            H ++LL     P  +  +             +L  +G+ F+    E   L  +Y  S     G+L +P++K+DD   P F NLIA+E C  +     +T YI  +D LI+   DV  L  K I+ N LG++  V  LFN +  +     D Y + V + + ++ D   NR  A   H++F SPW G +           ++QT++S
Sbjct:    8 EVATSLQGRLDRLTPLSATCCIYRVPQKLRKVNM---------EAYTPRVVSIGPLHHGE-EHLIAMEEHKLRYLQNFLHRTRKTLEECVEIISREEKTARDCYMEPINMS-SKEFVE-MILVDGCFIIEVILGFQNWNGRTGKPDDRIFNKPWLIYDVRRDMTLLENQLPLFLLLTLYSQLEVPRHQNHYDSFLLLSVNFFKFYSQMPEAKKIK------------HFVDLLIVCQQPSSTRPQNRSDFKFMIPSATQLHEAGVRFELGSKEERLLDIVYRRS----DGVLKIPRLKLDDKCEPLFRNLIAFEQC-HYRERLYITDYITLMDQLINTTKDVDVLVNKGIIENLLGDNVAVTNLFNNLLINATTGTDFYLADVTEGLSEYCDVPWNRWKAALRHDYFCSPWRGASTIAAVILLLLTLIQTIFS 411          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFI---------YKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEE--------LQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPN-NDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYH 1368
            I ++P  LR+    DK Y P + +LGP+HH R  +    ++ K +   + ++ +  +    L  +++   + R CY  E T          M+ +DGC  LE             Y   +     R  +  ++ D+                    + K  +  ++  +G  +      DQ G +     +RS         P   + + R +     ++K+ +        L+ +GI FK  + +    I F +     GIL +P++ + D T+  F+NLIA+E C  D  ND  +TSY+ F+DSLI+ P+DV +L    I+ ++LG++ EVA LFN +  ++V + ND Y S                         S PWT I+F            QT Y+V  Y+
Sbjct:  102 IYRLPHYLREGD--DKAYIPQIVSLGPYHHGRR-RLRNMDRHKWRSLHHILKRTNHDIEIYLDAMKELEEKARACY--EGTICLSSNEFVEMMVLDGCFILELFRGVAGGFKHLGYARNDPVFAIRGSMHSIQRDMIMLENQIPLFP---------LTKSDRNRLESSLGYTTTFDPLGDQGGLHCLEVFRRSL--LRTGPRPVPRIWMKRWSHSNRVADKRRQQLIHCVTQLREAGIKFKKRKTDRFWDIKFKN-----GILRIPRLLIHDGTKSLFLNLIAFEQCHLDCSND--ITSYVIFMDSLINSPEDVGYLHYCGIMEHWLGSESEVADLFNRLCQEVVFDINDSYLS-------------------------SFPWTIISFVAAVVLLALTFAQTFYAVYSYY 463          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEE-------------LQASGIHFK----PSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIY--SSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            I +VP  LR+     + Y P V ++GP HH         E+ KL+    F+ ++++   + ++ +     + R  Y  E+ K   +EF+  M+ VD C  +E I  +    + +            I+                   +   L  S+     R  P   P +QN     +    S+       E  H ++LL   + P  S    E             L+ +G+ FK      + + L  + + +     G+L +P + + +     F NLIAYE C D H    +T Y+  +D LI+   DV  L +K I+ N LG++  V  LFN +  D     + +  + + +++  +YD+  NR  A   H++FSSPW G +           ++QTV++
Sbjct:   29 IYRVPQKLRKANM--EAYTPRVVSIGPLHHGE-EHLVAMEEHKLRYLQKFLSETRKTLEECVEIIYREEEKARGYY-MESIKMSREEFVK-MILVDACFIIEVILGFSSSHSIE--------TGDRIYNKPRLFIDVRRDMTLLENQLPFFLLLSLYSL--RAPPGPLPENQNDYAHYSFLLLSKKISS-RHEIKHFVDLLIVCLQPSSSSLPPESKSFKFVIPTATYLREAGVRFKLGSKDKDNDKLLDLDYNN-----GVLKIPHLILQEKCESLFRNLIAYEECHD-HAQTYITDYMYLMDHLINTTKDVNLLVRKGIISNHLGDNHAVKNLFNRLLIDTTTCKETFHFAGIYEKLNKYYDSPWNRWQATLRHDYFSSPWRGASTIAAVILLVLTLIQTVFT 411          

Query:  838 EMLVKELSHHSVTPVVVVIFYLVFNRGVNVIVRHQVSAYLIEELSHLLVIPKEVSKYLLFPQMLYIIGLIDERIEEAYVRCDPEIIVEIGTHFVGYQVHELGSGRVVDFYLRKMKDSME*MERPKIYAPQ*VALTRFKMDPRCLKL 1275
            EM+VK LS+ S+  ++VV+   +F   +++ + +QV A L+E L H+++  K+V + +L  Q+L I+ +I+E ++EAYVR D  +I  I THF+GY V ELG   V++ Y  K + + E +   +    Q    TRF++DP   KL
Sbjct:   29 EMVVKGLSYPSIHSLLVVLLNTIFYIFISIGI-YQVIADLVENLGHIVIAAKKVVENVLRSQLLDIVCMINEVVKEAYVRSDRIVIWGIWTHFIGYHVQELGLREVINGYWGKFQVAKEEVGFER-NVSQETRSTRFEIDPGSFKL 172          

Query:   94 VSITIHEEASP-REERLNKLR---EEAPPIQAEKVK-PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYD---ELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKK---------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHS 1371
            + I + + AS  RE+R   +    E++   Q  + K  +I KVP MLR  K F   +EP V ++GP+HH +      AE +K  +   F+ +S+Q    L  K+   I+ELR CY++ ATKKY+DE LAWM+ VDGCS L FI  Y    +L++  IK    AF + D+F                     +E  + I++F+G  +    PA ++                 E +P HLL+LLR  +L  ++  +                EL+A+GI FKP++  SLR I F S+ L  G L LP+I +DDST+ +F+NLIAYEMCP+  N+  VTSYICFLDSLID P+DVK LR++ +LRNFLG+D+EVA+LFNEI TDLVP++D Y  VK +I+ HY+   +  +A+  H HFSSPWT +AF           +QT Y+V   H+
Sbjct:   47 IDIVVEDNASSSREKRFKSVMGGPEDSKRSQLSETKWARIPKVPHMLRGTKDFKILFEPRVVSVGPYHHHK-HDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDEDLAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGF--EEGMQMIEQFIGSAAETDPPAVKSDN---------------EEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILL-GFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRHN 476          

Query:   79 PAEIEVSITIHEEASPREER-LNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKE--LKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML-------------PYESEKK---------------------------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLG 1362
            P E  + I    E SPR +  +  LR+     +++   P+  KVP MLR  + F K YEP V ++GP+HH + P     E IK   A  F+ DS Q+   L  K+  NI  +RKCYD  +T +YDDE LAWM+ +DGC  L+FI +  ++ NF ++  Q+ FV  D+F                    + +  +KK I EFV +              PEA ++      E++ EP HLL LLR+++L               + EKK                                 ++L+ASGIH KPS  + L  + F S   FHG L LP+I +DD T+ KF+N++AYEMCPD  +D+G+TSYIC LD LID  DDVK LR K IL N LGNDE+VAQLFNEIG DLV + + Y  VKD+I++HY+   N  +AQ  H+HFS+PWT IAF           VQT Y++ G
Sbjct:   29 PKEHRIDIN---EISPRVKNWIGGLRKTEERTESQTQWPRTPKVPQMLRGTQDFKKMYEPRVISIGPYHHGK-PDLGRVEMIKPPCAQEFLADSNQDIEALYTKIRSNIETVRKCYDWSSTSEYDDEALAWMMLLDGCFLLQFIRRKGKI-NF-LRNHQIIFVLQDLFLLENQLPYGVLKLIFEEAKFNDDSLMKKKIKEFVTKTG-----------RPEASDE------ELDEEPPHLLHLLRSSLLGRDKRIRGSQPEQEQQPEKKGKSSSSQGGDWGFRCPWKKCKQRAIWLYSFRSIKDLKASGIHLKPSRTSVLTDVSFKS-SFFHGYLKLPRIIIDDFTKKKFLNMVAYEMCPDAPDDYGITSYICLLDDLIDHADDVKELRSKNILYNLLGNDEDVAQLFNEIGNDLV-DPEAYEDVKDRIQEHYNKRMNTWIAQALHDHFSTPWTIIAFIAAVLILFLTGVQTYYALPG 480          

Query:  106 IHEEASPREERLNKLREEAPP-IQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKY----DELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKE--LKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML----------PYESEKK-----------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            I  E +P  E  N++ ++A   I ++   P++ KVP MLR  + F K YEP V ++GP+HH + P     E IK   A  F+    Q+  DL  K+E  I  +RKCYD + T +Y+DE L WM+ +DG   L+FI       D++ N  ++  Q+ FV  D+F                         ++K+I EFV   +    P   + +    EE +         EP+HLLELLR+ +L            E+EKK                 +EL+A+GI+ KPS  + L  I F S H F+G L LP+I +D  T+ KF+N++AYEMCPD   D  VTSY+CFL  LIDQ DDVK LR K IL N LG+DE+VA++FNEIG DLV +   Y  VK +I+ HYD   N  +A+  HEHF SPWT  +            +QT Y+
Sbjct:   34 IDVEINPTVENWNRIVQKAKERIPSQSQWPRLPKVPHMLRGTQDFKKLYEPRVISIGPYHHGK-PHLRPGEMIKPLYAEQFLAGINQDFKDLYTKIESKIEAVRKCYDTKPTNRYNDEALIWMMLLDGLFLLQFIGSTVDPRDDMSNV-LRDHQINFVTQDLFLLENQLPFGVLKLIFEGANFQDAPPMEKTIKEFV---TDFGMPEGLSSEIQLEEENK---------EPSHLLELLRSALLGGYKKIQPKQKQEAEKKGKSSSSGGGIWESFRHIKELKAAGIYLKPSRKSFLTEISFKS-HFFYGCLKLPRITIDGFTKTKFLNMVAYEMCPDAPVDQAVTSYVCFLYELIDQADDVKELRSKHILHNLLGSDEDVAKIFNEIGNDLV-DPGAYGDVKARIQKHYDKRVNTWIAEGLHEHFRSPWTFTSLIAAVWILIVTGLQTYYA 467          

Query:  121 SPREERLNKLREEAPPIQAEKVKP-KIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFI-YKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAP--------ADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYES--------------EKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            S R+  L+ + E+       K +  KIQKVP MLR D+  +K ++P V ++GP+H  + P+ +  E++K +     V +SK  D DL  +V   + + RKCY E +T + DD   A M+F+DGC  L+FI    D+ +   IK   VAFV  D+F                      E  + I+ FV  N+ A +P         D+  +    E  +++  Q+ E +P HLL +L   ++                      EL+A+GI FKPS+      + F    L  G L LP + VDDSTR   +NL+AYE CP   +DFGVTSY+CF+D LID  +DVK LR   IL NFLGND++VA+LFNEI  DLVPN   Y+ VK  IE HY+N     +A++ H HF+SPWT +AF           VQT ++
Sbjct:   54 SSRDPWLSSIMEDGGESGENKSQQSKIQKVPAMLRDDESNNKCFDPWVVSIGPYHRGK-PELQLMERLKKETVRQHVTESKVEDQDLYNRVVKVVGDARKCYKEGSTDELDDREFAQMMFLDGCFILQFICCSTDKDKKMNIKNHNVAFVRRDLFLLENQLPFLVLEALMLPK--KDEWLEKINNFVD-NTRAHSPDHHKQGGWLDRITKKLFREVPQAKEEQQPEQQPVHLLGILHAQLINQSDLNALSCSMSDWSSYRSANELKAAGIQFKPSKTRRFTDVNFEP-ALSFGTLELPPMMVDDSTRSMLLNLVAYESCPGAPDDFGVTSYLCFMDVLIDHAEDVKVLRSNGILLNFLGNDKQVAKLFNEIAKDLVPNPHAYARVKGDIEKHYNNKAKIWIAEWLHTHFTSPWTFLAFLGAILALALSCVQTYFA 483          

Query:  193 KIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIY-----KYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKE-LKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML--------------------PYESEKK---------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYH 1368
            KI KVP MLR  + F+K+YEP V + GP+HH + P     E +K      F+RDS Q+  +L +K+E NI  +R CYDE+ T KYDDE LAWM+ +DGCS L FI         +L +  +K   VAFV+ D F                   +  + +++ I+ F+  N   A P      +            ++  +P+HLL+LLR+ +L                    P E  K+         +EL+A+GI+ KPS    +R I F S+  F G L LP I +D ST+ K +NL AYEM P+   DFGVTSYICFLDSLI   +DV  L+    L NFLG+DE+VA LFN+I  DLVPN D Y+ VK  ++ HY+   N  ++++ H +F    T +AF          I QT ++    H
Sbjct:   61 KIPKVPQMLRHTQDFEKFYEPRVISFGPYHHGK-PHLLQGEMLKPLCGRRFLRDSGQSIQNLYRKIESNIKLVRMCYDEDQTYKYDDEELAWMMLLDGCSLLYFILCVMRRNESQLSDLNVKSHFVAFVQLDCFLLENQLPFGILELLFEGARLGADTMEEMIERFITSN--IAKPRGTMASD-----------LDLVKDPSHLLDLLRSGLLGPQPVPEQKGQPEGIWRGTGPREMRKQGDWQSYRNIKELEAAGIYLKPSRTTYMRDISFESYFFF-GYLKLPHITIDASTKLKLLNLAAYEMSPNGPGDFGVTSYICFLDSLIKNAEDVMLLQSNYTLFNFLGSDEKVADLFNDIAKDLVPNRDAYALVKAGVQKHYNTRVNVWISKWLHSNF----TFLAFIGAVVALGSSICQTYFAAFPPH 468          

Query:  187 KPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEE---------ATKKYDDEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEV---EAEPTHLLELLRTTMLPYESEKK-EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            +PKIQ+V   LR  K F+K+Y P   ++GP HH        AEK KL  AA ++ ++     DL KK+ DNI+EL+  +D++         A  +  +E L+WMLFVDGCS L  + K   +E  +  IK DQ+  V  D+                        L +S+  F+  +  A     Q+G+  +   +R   G  +   EA   +L +  R   +   + +  ++L+  GI+FK S+    R I F S  LF   L LP+I VDDS+   F+NLIAYEMCPDFHND+G+ S+  F+DSLID P+DVK LR K+IL N LG+DEEVA+LFN I TDLVPN D Y  V+ +I DHY N  N  +AQ F  +FSSPW  IAF           +QT ++V
Sbjct:   24 RPKIQRVLKSLRNRKNFEKHYSPKCVSIGPIHHHNT-NLILAEKYKLMWAAKYIENNGYIPEDLHKKIADNIDELKGHFDDDVLTSTRWSLAGFRSLEEKLSWMLFVDGCSLLYILEKANLNEPWHMNIKVDQLVLVMMDVLLLENQLPYQVLKLLWKDED-ESGLIESMMNFLDCHHWATPDESQSGKKKDMVPKRKGEGVTIRNNEANKENLSKKSRDEKVKMMTYRNIQDLRDVGINFKSSKTRRPRDIDF-SEGLFTAELTLPEIVVDDSSATTFLNLIAYEMCPDFHNDYGICSFAAFMDSLIDNPEDVKLLRSKEILLNSLGSDEEVAELFNIISTDLVPNADTYLEVRAKIHDHYRNRCNTWIAQGFRTYFSSPWAIIAFIAALIALVLTFIQTWFTV 425          

Query:  187 KPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEAT----KKYDD-----EFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQN-----------------------------GQNPEAEEQRSQPGQEVEAE-------------PTHLLELLR-------TTMLPYESEKK---------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            +PKIQ+V   LR  K F+K+Y P + ++GP HH   P  +  EK KL  AA ++ +  +N  DL KK+ DNINEL+  + ++      +  +D     E L+WMLFVDGCS L  + K          IK DQ+  V  D+                       EL KS+  F+  +  A     +N                              + P  +E+   P ++ E E             P HLL+L R       TT +  ES  +               ++L+A GI  K S+    R I F S  LF   L LP+I VDD++   F+NLIAYEMCPDF ND+G+ S+  F+DSLID P+DVK LR K IL N LG+DEEVA+LFN I TDLVPN++ Y  V+ +I DHY N  N  +A+ FH +FS+PW  IAF           +QT ++V
Sbjct:   26 RPKIQRVQEYLRNRKNFEKHYSPKLVSIGPIHHDN-PNLKTGEKYKLMWAAKYLENIGRNPRDLHKKIADNINELKGHFSDDVLTLTGQSLEDFGSLEEKLSWMLFVDGCSLLHILEKAKLHVPGQMNIKVDQLVLVMMDVLLLENQLPYEVLKLLWKDSD-ESELIKSMKNFLKCHHWATPDNKRNRRKRRNQETSNIVPDKTGKEQHSVLITNESETPSEKEKDMVPKRKGEGEHSLSIRNESQLETPFHLLDLQRNIILITSTTKINKESWSQKSSDEKVKMMTYRNIQDLRAVGIRLKSSKTRRPRDIDF-SEGLFAAELTLPEIVVDDTSAATFLNLIAYEMCPDFDNDYGICSFAAFMDSLIDNPEDVKLLRSKGILLNSLGSDEEVAELFNIISTDLVPNSETYFEVRAKIHDHYCNRCNTWIAEGFHTYFSNPWAIIAFIAAFTALVLTFIQTWFTV 487          

Query:  172 QAEKVK-------PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKY-DDEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXX------IHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQ------------------RSQPGQEVEAEPT-HLLELLRTTMLPYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHS 1371
            Q EK K       PKIQ+V   LR  K F K+Y P + ++GP HH         EK KL   A ++  + Q+   L +K+  NI +L++ + E+    + DDE L+WML VDGCS L+ + K   D  E   +K DQ+  V  D+                          I KE  K       R +  A   D +    + E++                  + +   E+  EP  HLL+ LR T          EL+A+GI  K S    ++   F    L+   L LP+I VDD+T P F+NLIAYEMCPDF N++ + S++ F+DSLID PDDVK LRK  IL N LG+DEEVA LFN I  DLVPN + YS V+ QIE HY N     +A   H +FS+PW  IAF           +QT Y++   H+
Sbjct:   13 QLEKAKLIPQTSAPKIQRVAHYLRDRKHFAKHYSPRLVSIGPIHHGA-KNLLLGEKYKLMWTARYLERTNQDAQTLYQKIASNIKQLKELFAEDVIADFPDDEKLSWMLLVDGCSLLQILEKGKLDYPEEMNVKVDQLVLVWQDVLLLENQLPYQVLKLLTGPENEAMLLNIMKEFLKCHHLSPVRPNHRAKTQDMDKDITKQEDRAFTEEGCTSVCTKNESTLQGEHRVEIPQEPPIHLLDQLRRT----------ELRAAGISLKKSNSRRIKDTSFSCGWLY-AELKLPEITVDDTTAPSFLNLIAYEMCPDFTNNYEICSFVAFIDSLIDNPDDVKELRKAGILLNMLGSDEEVANLFNTISADLVPNMEGYSHVRPQIERHYRNKCKTWIALGSHTYFSNPWAIIAFHAAVLAIVLTFIQTWYAIHPAHA 435          

Query:  175 AEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKY-DDEFLAW--MLFVDGCSTLEFIYKYD--ELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRN--SPAAAPADQN-GQNPEAEEQRSQPGQEV--------------EAEPTHLLELLRTTML--PYESEKKE------------------------ELQASGIHFKPSEGNS-LRSIYFG-SFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            A+   PKIQ+VP  LR  + F K+Y P + ++GP HH    + +  EK KL  AA ++  +KQ+   L +K+  NI +L+  + E+  + + DDE L+W  MLFVDGCS L+ + K +  + +   +K DQ+  V  D+                      K L KS++EF+  +  SP      Q+ G +   +E R+Q  + +                 P HLL+ LR  +L  P++ +K E                        EL+A+GI  K  +    LR + F   +      L LPQI VDD+T P F+NLIAYEMCPDF N+F + S++ F+DSLID P+DVK LR  ++L N LG+DE+VA+LFN I  DLVP+ + Y  V+ QIE HY +     +A  +H +FS+PW  IAF           +QT +++
Sbjct:   21 AQNSVPKIQRVPHHLRDRENFAKHYLPRLVSIGPIHHGA-EKLQLGEKYKLMWAAMYLERTKQDAQTLYQKIASNIEQLKDLFAEDVIRDFPDDEKLSWSWMLFVDGCSLLQILEKGELQDPKEMNVKVDQLVLVWQDVLLLENQLPYHVLKLLSDHEDDAK-LVKSMNEFLKCHHLSPELRSKKQDIGNSMTKDEHRTQTPKSLYIIIGVLHVDMLYFHESPIHLLDQLRRYVLDDPHKKQKNETGNVKKEDQNTNEDLDMTTYRNIQELRAAGIKLKRDKSRRRLRDVSFSYRWMCLCAELTLPQITVDDTTTPTFLNLIAYEMCPDFKNNFEICSFVVFMDSLIDHPEDVKELRAAKVLHNALGSDEDVAKLFNTISADLVPDMESYLHVRRQIEKHYRSKYRTWIALGYHTYFSNPWAVIAFHAALVVLVLTFIQTWFTI 462          

Query:  115 EASPREER-LNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKR----DQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDE--FVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEA-EPTHLLELLRTTMLPYESEKKE---------------------------------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMA 1254
            E SPR +  +  L+      Q++   P+I KVP +LR    F++ YEP V ++GP+HH + P  +  E IKL+ A  F+ DS Q+   L  K+  NI  LRKCYD+  T   DDE LAWM+ +DGC  L+FI    +     +       Q+ FVE D+F                   +  +L   + +  F G      +  +Q  +N        QP  E+   E +HLL+LLR+ +L   + K+E                                       EL+A+GIH +PS    L  I F S+  F G L+LP I VDDST+ +F+N++AYEMCPD  ND+ VTSY+ FL  LID  DDVK LR + IL N LG+DE+VA++FNEI  D+V + ++Y  VK +I+  Y+   N  +A
Sbjct:   39 EISPRVKNWIKSLKNAEESTQSQSSWPRIPKVPQLLRGTHDFERLYEPRVISIGPYHHGK-PHLQPVETIKLQYAQKFLADSDQDIEALYTKIGSNIEALRKCYDKIPT---DDEKLAWMMLLDGCFLLQFIRSRKDGSTVDLSNVLRIHQINFVERDLFL------------------LENQLPFGVLQLIFEGAKFNDGSTMEQMIKNFVTRIASLQPSSEIRLDERSHLLDLLRSAILGKSAPKQERQPDKKGKSSSSSGGDGRFCCPWKKGKQQGIRQSFRNIKELKAAGIHLQPSRTRFLTDISFNSY-FFRGYLNLPPIIVDDSTKSRFLNIVAYEMCPDAPNDYTVTSYLRFLYELIDHADDVKELRSRHILINHLGSDEDVARIFNEIANDVV-DTEVYGDVKARIQKDYNKRVNTCIA 441          

Query:  241 KYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDAD---LLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKS--IDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEELQASGIHFKPSEGNS---------------------LRSIYFG----------SFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDQPDDVKHLRK-KQILRNFLGNDEEVAQLFNEIGTDLVPNNDI--YSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHSSK 1377
            K Y+P V ++GP+H+      +  ++ K +L   F+ ++K+ D +   L+K V D  +++RK Y EE    +D   L +M+ +DGC  L           F I    +   E  IF                   +   + ++  +   +G +S     A    +NP  +++ S   +    +  HLL+L+R T LP  SE  ++  +  +  +  EG S                     L+ I F           +  L    L +PQ++ D      F+N +A+E    F+ D    +T+YI F+  L++  +DV  LR  K I+ N  G++ EV++ F  I  D+V   D    ++V   + ++   W N + A F H HF SPWT ++           ++Q+  ++L Y + K
Sbjct:   61 KAYKPKVVSIGPYHYGE-KHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMV---------FLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNP-IDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSES-DKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQ---FYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDK 462          

Query:  718 QNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFN 1155
            Q  EA   R +    ++ E   L+E L    +        +L  +G+ FKP+   ++ ++ F S     G  +LP I +D +T     NL+AYE   +       T Y   ++ +ID  +DV+ LR++ +L + L +D+E A+++N
Sbjct:  317 QENEATTTRQESVSILDIEKPPLVEELTIPSV-------SDLHKAGVRFKPTAHGNISTVTFDSNS---GQFYLPVINLDINTETVLRNLVAYE-ATNTSGPLVFTRYTELINGIIDSEEDVRLLREQGVLVSRLKSDQEAAEMWN 451          

Query:   79 PAEIEVSITIHEEASPREER------LNKLREEAPPIQAEKVKPK--IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQ-------------------IKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTH--LLELLRTTM--LPYES----EKKE-------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLV--PNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYH 1368
            P++IEV     +E  PRE R      +    E+A    A     K  I +VPF L+++ K  K Y P   ++GP+HH ++      E+ K +     +  +K N    +  +++   E R CY      K  +EF   ML +DGC  LE ++K   ++ FQ                   I+RD +  +E+ +                    I  E+     + +   S     ++++  + E  ++    G     +  H  L++   TT    PYE     EK++       EL+ +G++F   E   L  I F +     G L +P++ + D T+  F NLIA+E C    ++  +TSYI F+D+LI+   DV +L    I+ ++LG+D EVA LFN +  +++  P +   S +  ++  +Y    N + A    ++F++PW   +F            Q+ ++V  Y+
Sbjct:   50 PSKIEV-----KEEKPRETREEWVISIKDKMEKALSYDATNSWDKLCIYRVPFYLQENDK--KSYLPQTVSIGPYHHGKV-HLRPMERHKWRAVNMIMARTKHNIEMYIDAMKELEEEARACYQGPIDMKNSNEFTE-MLVLDGCFVLE-LFK-GTIQGFQKIGYARNDPVFAKRGLMHSIQRDMI-MLENQLPLFVLDRLLGLQTGTPNQTGIVAEVAVRFFKTLMPTSEVLTKSERSLDSQEKSDELGDNGGLHCLDVFHRSLIQSSETTNQGTPYEDMSMVEKQQQLIHCVTELRGAGVNFMRKETGQLWDIEFKN-----GYLKIPKLLIHDGTKSLFSNLIAFEQCHTQSSN-NITSYIIFMDNLINSSQDVSYLHHDGIIEHWLGSDSEVADLFNRLCKEVIFDPKDGYLSQLSREVNRYYSRKWNSLKATLRQKYFNNPWAYFSFSAAVILLFLTFFQSFFAVYAYY 505          

Query:  130 EERLNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHA--RLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFI---------YKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQ----PGQEVEAEPTHLLELLRTTML------------------PYESEKKE--------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFN----EIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGY 1365
            ++++ ++  +A     +K+   I +VP  L++  K    Y P   +LGP+HH    L   +Y +   + +     +   +   D +K++E+     R CY  E            ML +DGC  L+             YD  +     R  +  +  D+                      +     + +   R      P   +    E  ++ +     P  + E E  H L++ R ++L                  P  ++K++        EL+ +GI FK  + +    I F +     G L +P++ + D T+  F NLIAYE C  D  ND  +TSYI F+D+LID  +D+++L    I+ ++LGND EVA +FN    E+  DL   N   S + ++++ +Y+   N + A   H++FS+PW   +F          + Q+ ++   Y
Sbjct:   95 KDKMEQVMRDAATTSWDKIC--IYRVPLSLKKSDK--NSYFPQAVSLGPYHHGDEHLRPMDYHKWRAVNMVMKRTKQGIEMYIDAMKELEERA---RACY--EGPIGLSSNKFTQMLVLDGCFVLDLFRGAYEGFSKLGYDRNDPVFAMRGSMHSIRRDMLMLENQLPLFVLNRLLELQLGTQYQTGLVAQLAVRFFNPLMPTYMSSTKIENSQENNNKFFNPIADKEKEELHCLDVFRRSLLQPSLKPDPRLSRSRWSRKPLVADKRQQQLLHCVTELREAGIKFKRRKSDRFWDIQFKN-----GCLEIPKLLIHDGTKSLFSNLIAYEQCHIDSTND--ITSYIIFMDNLIDSAEDIRYLHYYDIIEHWLGNDSEVADVFNRLCQEVAFDL--ENTYLSELSNKVDRYYNRKWNVLKATLKHKYFSNPWAYFSFFAAVILLLLTLFQSFFTSYPY 534          

Query:  121 SPREERLNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHAR---LPQYEYAEKIKLKLAANFVRDSKQNDA----DLLKKVEDNINELRKCYD---EEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELEN-----------------FQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQ----NPEAEEQRSQ-------------PGQEVEAEPTHLLELLRTTMLPYESEKK----EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLV--PNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGY 1365
            S R++    LRE+A        K  I +VP  L+++ K  K Y P   +LGPFHH     LP   +  +     A N V    ++D     D +K++ED     R CY+   + ++ K+ +     ML +DGC  LE     DE  +                   I+RD V                           + +   +  D  +  + P     D   Q    NP A++ + +             P    E   + +    RT +     ++      EL+ +GI F+  + +    I F +     G L +P++ + D T+  F NLIA+E C  D  ND  +TSYI F+D+LID  +DV++L    I+ ++LGND EVA LFN +  ++   P N   S + ++++ +Y    N + A   H++F++PW   +F          + Q+ ++   Y
Sbjct:  119 SIRDKMEQALREDAT---TSWDKLCIYRVPQYLQENNK--KSYFPQTVSLGPFHHGNKHLLPMDRHKWR-----AVNMVMARTKHDIEMYIDAMKELEDRA---RACYEGPIDLSSNKFSE-----MLVLDGCFVLELFRGADEGFSELGYDRNDPVFAMRGSMHSIQRDMVMLENQLPLFVLNRLLEIQLGKRHQTGLVSRLAVRFFDPLMPTDEPLTKTDDSLEQDKFFNPIADKDKGELHCLDVFRRNLLRPCSNPEPRLSRMRWSWRTRVADKRQQQLIHCVTELREAGIKFRTRKTDRFWDIRFKN-----GYLEIPKLLIHDGTKSLFSNLIAFEQCHIDSSND--ITSYIIFMDNLIDSSEDVRYLHYCGIIEHWLGNDYEVADLFNRLCQEVAFDPQNSYLSQLSNKVDRNYSRKWNVLKAILKHKYFNNPWAYFSFFAALVLLVLTLFQSFFTAYPY 559          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEF----IYKYDEL-------------ENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML-------PYESEKK-------------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLV-PNNDIY-SSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYH 1368
            I +VP+ L+++   +K Y P   +LGP+HH +  +    ++ K +     ++ + Q     +  + +   + R CY+   +    +EF+  ML +DGC  LE     +  + EL                 I+RD V                           + +   +  D  +  + P         +N  A ++   P  ++     H L++ R ++L       P  + K+                    EL+ +GI F+  + +    + F +     G L +P++ + D T+  F+NLIA+E C  D  ND  +TSYI F+D+LID  +DV +L    I+ ++LG+D EVA LFN +  ++V    D Y S +  ++  +YD+  N   A   H++F++PW  ++F            Q+ Y+V  Y+
Sbjct:  105 IYRVPYYLQEND--NKSYFPQTVSLGPYHHGK-KRLRSMDRHKWRAVNRVLKRTNQGIKMYIDAMRELEEKARACYEGPLSLS-SNEFIE-MLVLDGCFVLELFRGAVEGFTELGYARNDPVFAMRGSMHSIQRDMVMLENQLPLFVLNRLLELQLGTRNQTGLVAQLAIRFFDPLMPTDEPLTKSGQSKLENSLARDKSFDPFADMGE--LHCLDVFRRSLLRSSPKPEPRLTRKRWSRNTRVADKRRQQLIHCVTELKEAGIKFRRRKTDRFWDMQFKN-----GYLEIPRLLIHDGTKSLFLNLIAFEQCHIDSSND--ITSYIIFMDNLIDSHEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDTEDSYLSRLSIEVNRYYDHKWNAWRATLKHKYFNNPWAIVSFCAAVILLVLTFSQSFYAVYAYY 527          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDA----DLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEP--THLLELLRTTMLPYESEKKE-----------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLV--PNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGY 1365
            I +VP  L+++    K Y P + ++GP+HH         E+ K + A N V    ++D     D +K++E+   + R CY        + EF+  ML +DG   +E I+K    E FQ    ++ +  +D                     +  +L  S+ + + +          N Q  +   Q   P +EV  E    H L++LR  +L       E                 EL+ +G+ F   E       +F      +G L +P++ + D T+  F+NLIA+E C    +   +TSYI F+D+LI+  +DV +L    I+ N+LG+D EV+ LFN +G +++  PN+   S++  ++  +Y    N + A   H++F++PW   +F            Q+ ++V  Y
Sbjct:  106 IYRVPPYLQENDT--KSYMPQIVSIGPYHHGH-KHLMPMERHKWR-AVNMVMARAKHDIEMYIDAMKELEE---KARACYQGPINMNRN-EFIE-MLVLDGVFIIE-IFKGTS-EGFQ----EIGYAPND---PVFGMRGLMQSIRRDMVMLENQLPWSVLKGLLQLQRPDVLDKVNVQLFQPFFQPLLPTREVLTEEGGLHCLDVLRRGLLQSSGTSDEDMSMVNKQPQQLIHCVTELRNAGVEFMRKETG-----HFWDIEFKNGYLKIPKLLIHDGTKSLFLNLIAFEQC-HIKSSKKITSYIIFMDNLINSSEDVSYLHHYGIIENWLGSDSEVSDLFNGLGKEVIFDPNDGYLSALTGEVNIYYRRKWNYLKATLRHKYFNNPWAYFSFIAAVTLLIFTFCQSFFAVFAY 496          

Query:  241 KYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQND---ADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHD--IFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFV------GRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKK----------------------EELQASGIHFKPSEG-NSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYE-MCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPN--NDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWT 1290
            K YEP + ++GP+HH +    +  ++ K +    FV   ++      +L+K V      +R  Y E+     D E L  M+ +DGC  L   +         +   +V +   D  IF                   +   L +++ E        G N  A    + + Q PE   ++         E  HLL+L+R T +P  S+++                      ++L   GI FKP +  +S+  I + +     G+LH+P + +DD T   F+N +A+E +  D  N   +TSY+ F+  LI++  D   L +++IL N+ G ++EV++ +  IG D+  +      + V + + ++     +   A+F H HF SPWT
Sbjct:   46 KAYEPKIVSIGPYHHGK-EHLKMTQQHKRRFLKFFVAKMEEKGFVPQELVKAVSSLEGVIRGSYSEDLG--LDSENLVQMMVLDGCFILTLFF---------VVSGKVEYTNLDDPIFRMPWILPSIRADLLLLENQVPYVLLQTLFETSKLVTCSGLNEIAFEFFNYSLQKPETFWEK-----HYGLEAKHLLDLIRKTFVPVPSQRRIKDHSSKSSFNDHEYLGFVLSAKKLHLRGIKFKPRKNTDSILDISYSN-----GVLHIPPVVMDDFTASIFLNCVAFEQLYADSSNH--ITSYVAFMACLINEESDASFLSERRILENYFGTEDEVSRFYKRIGKDIALDLEKSYLAKVFEGVNEYTSQGFHVHCAEFIHTHFDSPWT 408          

Query:  241 KYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDAD---LLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKS--IDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEELQASGIHFKPSEGNS---------------------LRSIYFG----------SFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDQPDDVKHLRK-KQILRNFLGNDEEVAQLFNEIGTDLVPNNDI--YSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHSSK 1377
            K Y+P V ++GP+H+      +  ++ K +L   F+ ++K+ D +   L+K V D  +++RK Y EE    +D   L +M+ +DGC  L           F I    +   E  IF                   +   + ++  +   +G +S     A    +NP  +++ S   +    +  HLL+L+R T LP  SE  ++  +  +  +  EG S                     L+ I F           +  L    L +PQ++ D      F+N +A+E    F+ D    +T+YI F+  L++  +DV  LR  K I+ N  G++ EV++ F  I  D+V   D    ++V   + ++   W N + A F H HF SPWT ++           ++Q+  ++L Y + K
Sbjct:   61 KAYKPKVVSIGPYHYGE-KHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMV---------FLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNP-IDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSES-DKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQ---FYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDK 462          

Query:  241 KYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDAD---LLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKS--IDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEELQASGIHFKPSEGNS---------------------LRSIYFG----------SFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFG--VTSYICFLDSLIDQPDDVKHLRK-KQILRNFLGNDEEVAQLFNEIGTDLVPNNDI--YSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHSSK 1377
            K Y+P V ++GP+H+      +  ++ K +L   F+ ++K+ D +   L+K V D  +++RK Y EE    +D   L +M+ +DGC  L           F I    +   E  IF                   +   + ++  +   +G +S     A    +NP  +++ S   +    +  HLL+L+R T LP  SE  ++  +  +  +  EG S                     L+ I F           +  L    L +PQ++ D      F+N +A+E    F+ D    +T+YI F+  L++  +DV  LR  K I+ N  G++ EV++ F  I  D+V   D    ++V   + ++   W N + A F H HF SPWT ++           ++Q+  ++L Y + K
Sbjct:   61 KAYKPKVVSIGPYHYGE-KHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMV---------FLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGSKIGVSSDLNRIAFHFFKNP-IDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSES-DKASSPHVQVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKNKLQIPQLRFDGFISSFFLNCVAFEQ---FYTDSSNEITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAILSYLNDK 462          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYK--YDEL--ENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKE-------------ELQASGIHFKPSEGNS-LRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIY-SSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVL 1359
            I KVP  LR+       Y P + + GP H  +  + +  E  K +   +F+  +  +  DL++         R CY E+  K + DEF+  ML VDG   +E + +  Y  L  EN +I  + +   +                       + KE+   +  +  + +P+     Q  Q   +        ++   EP H ++LLR+  LP    K E             EL  +G+ FKP+E +S L  I F       G+L +P I VDD T   + N+I +E C   + +F    YI  L   I  P D   L    I+ N+LGN  +V+ LFN I  +++ +   Y S + + ++ + +   NR  A    ++F +PW   +            +Q+V S+L
Sbjct:  295 IYKVPNKLRRLNP--DAYTPRLVSFGPLHRGK-EELQAMEDQKYRYLLSFIPRTNSSLEDLVRLARTWEQNARSCYAEDV-KLHSDEFVE-MLVVDGSFLVELLLRSHYPRLRGENDRIFGNSMMITD--------VCRDMILIENQLPFFVVKEIFLLLLNYYQQGTPSII---QLAQRHFSYFLSRIDDEKFITEPEHFVDLLRSCYLPQFPIKLEYTTVKVDNAPEATELHTAGVRFKPAETSSCLLDISFAD-----GVLKIPTIVVDDLTESLYKNIIGFEQCRCSNKNF--LDYIMLLGCFIKSPTDADLLIHSGIIVNYLGNSVDVSNLFNSISKEVIYDRRFYFSMLSENLQAYCNTPWNRWKAILRRDYFHNPWAVASVFAALLLLLLTFIQSVCSIL 678          

Query:  133 ERLNKLREEAPPI---QAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLK-LAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEK---------KEELQASGIHFKPS---EGNSLRSIYFGSFHLF----HGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLV--PNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            ER++K  +E P +    A K    I +VP  +       + YEP V ++GP+H  +  Q +  E+ K + L     R       D +K V++     R+CY E  T   D E    M+ +DGC  LE   K + L  F+     VA      F                   +    +   +     +  + A A  N      EE  ++  +E+ A+  HLL+LLR++ +P ESE          KE++ +  IH        G  LR +      L     HG + +P I VDD       N +AYE C         T+Y   LD L +   DV++L  + I+ N+ G D E+A+  N +G D+           + +++ ++Y +  +   A F   +F+SPW+ ++           ++QT+Y+V
Sbjct:   23 ERMHKKLKEPPRLLSSAAGKPTCSIFRVPQSMIDCN--GRCYEPRVVSIGPYHRGQT-QLKMIEEHKWRYLNVLLTRTQNLTLEDYMKSVKNVEEVARECYSE--TIHMDSEEFNEMMVLDGCFLLELFRKVNNLVPFEPNDPLVAMAWVLPFFYRDFLCLENQIPFFVLETLFNLTRGDNENETNASLQSLAFAFFNNMMHRTEEDLAR-FKELRAK--HLLDLLRSSFIP-ESELHTPPATNPGKEKMPSHIIHSISKLRRAGIKLRELKDAESFLVVRFRHGTIEMPAITVDDFMSSFLENCVAYEQC-HVACSMHFTTYATLLDCLTNTYKDVEYLCDQNIIENYFGTDTELAKFVNSLGRDVAFDITQCYLKDLFEEVNEYYKSSWHVEWATFKFTYFNSPWSFVSALAALVLLVLSVIQTIYTV 442          

Query:  151 REEAPPIQAEKVKPKIQKVPFMLRQDKKFDK-YYEPIVAALGPFHHARLPQYEYAEKIKLK--LAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKY-DELENFQIKRDQVA-FVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVG--RNSPAAAPAD-QNGQNPE--------AEEQRSQPGQEVEA-----EPTHLLELLRTTMLPYESEKKE----------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVL--GYHSSK 1377
            R+    +  E+      +VP + R++   ++  Y P+V ++GP+HH   P +E AE   LK  +   F  +S +    L  KVE+     +KCYDE +TK   D+    M+ +DGC  L+FI+ +  + +N ++    +A FV+ D+F                      E KK +++F+   R  P     D +NG+  +        A +  +QPG+  +      +P HLL+      +     ++                 EL++ GIHF PS+ +    I + S  +  G + LP+I +DDST+   +NL+A+E CP     FGVTSY+ F+DSLID P+DVK LRKK IL N LG+D+EVA LFNEI + +V + + Y +VK  IE H  N   +  A++ ++HFSSPWT +AF           +QT Y  L  G H +K
Sbjct:   27 RQHTIQVGQEESSKICHRVPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVQQFANESGKTREVLYSKVEELAVSAKKCYDERSTKDLGDKAFTEMMLLDGCFILQFIFCFLHDFQNLKLSNRVLAYFVKRDLFLLENQIPYEVLKSLMSLRFGDAEGKKLMEDFMDDVRGLPRDKSRDKENGKGLDCRFWSWRPAPKMNNQPGEIPQVPGEIPQPVHLLDFFHNRFMGGSRGQENLSLKGDGQWSSYRSVMELKSVGIHFMPSKTDMYTDILYKST-MRGGTVTLPRIVIDDSTKSLLLNLMAHEACPGPAEGFGVTSYVYFMDSLIDHPEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWAAEWLNDHFSSPWTFLAFFGAIFALVLTFIQT-YKTLYPGNHLNK 472          

Query:  178 EKVKPKIQKVPFMLRQDKKFDK-YYEPIVAALGPFHHARLPQYEYAEKIKLK--LAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKY-DELENFQIKRDQVA-FVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVG--RNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKE---------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVL--GYHSSK 1377
            E+   K  +VP + R++   ++  Y P+V ++GP+HH   P +E AE   LK  +   F  +S +   DL + V +  +  RKCYDE +TK   D     M+ +DGC  L+FI+ +  + +  ++    +A FV+ D+F                      + ++ ++ F+   R  P     D    N                +P HLL+      +    ++                 EL++ GIH  PS+ +    + + S  +  G + LP+I +DD T+   +NL+A+E CP     F VTSY+CFLDSLID  +DVK LRKK IL N LG+D+EVA LFNEI + +V + + Y +VK  IE H  N   + +A++ ++HFSSPWT +AF           +QT Y  L  G H +K
Sbjct:   13 EECSKKCHRVPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVEQFANNSGKTREDLYRNVAELASSARKCYDEGSTKNVGDNAFTKMMLLDGCFILQFIFCFLHDSQKLKLSNRVLAYFVKRDLFLLENQIPYKVLTSLMSLGFDGNKGQELMENFMDEVRGLPRGKSGDMENNN----------------QPAHLLDFYHNRFMGKRGQENPSRKGDSQWSSYRSVMELKSVGIHLMPSKTDMYTDLRYKST-MRGGTVTLPRIVIDDCTKSLLLNLMAHEACPGSAEGFWVTSYVCFLDSLIDHSEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWVAEWLNDHFSSPWTFLAFFGAIFALVLTFIQT-YKTLYPGNHLNK 418          

Query:  193 KIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHY 1227
            ++ +VP   R+ K+    YEP+V ++GP+HH +  + +  EK+K ++A  FV+DS+    ++  KV++ +++ RKCY EE+T++++DE    M+F+DG   L+ +   + L+   +++++VA V  D+F                   + +  K   D   G +  ++      G+  E E    + G+              T+   Y S   EEL+  GI F PS       + F +  L  G L +P + +++ T+P  +NL AYE C  ++ D   TSY+CF+ SLID+P+DVK LR K ILR  +G+D+ +AQ+F EI T+L PN   Y+ VK  +E HY
Sbjct:   16 EVPRVPSEFRKMKENTDCYEPLVVSIGPYHHGK-KELKEMEKLKAEMAGQFVKDSRVTAEEMYSKVKELVSDARKCYAEESTRQFNDEKFTQMMFLDGYFILQVV--SENLKQQNLRKEEVASVRRDLF------LLENQLPFRVLIPLMRIYKSKADHIAGEDKSSSRQFVYVGEELERERGGRRYGE-------------ITSWNRYYS--VEELKNVGISFMPSNTRVFTDVKFKN-TLLGGALCIPPLSIEEETKPLLLNLAAYETCAGWYYDMYCTSYVCFMRSLIDKPEDVKELRSKGILRTTIGSDDRIAQIFKEITTNLAPNPTAYTKVKRSVESHY 335          

Query:  190 PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHA-RLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAF-VEHDIFXXXXXXXXXXXXXXXXXXXIHKEL-KKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML-PYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            P I KVP  L+ D+   KYY+P V ++GP+H+  R  +   AEK+K+++A  FV  SK++   L  +V       ++ Y+  + + +DDE    M+F+DGC  L+FI      +N +   DQ  F V+ D+                      K+   K I++F+              Q  +    + +P      +   LL L+ TT+  P+      +LQ  GI+FKPS+ N+L  + F S  +F+  L LP I ++ +TR   +NL+AYE    F +D  VTSYICF+DSLI+  +DVK LR   IL N+LG D++VA LFN+IG    PN ++Y+ VK +I    D+   + +A+    +FSSPW  IAF            QT Y+
Sbjct:   69 PMIPKVPDNLKDDEN-KKYYKPSVVSIGPYHYKDRQNKLHEAEKLKVQMAREFVLYSKKDMEILYSEVAKVAENAKRFYEGSSIRCFDDEQFTQMMFLDGCFILQFIRCVSTTDNIKNMSDQQIFHVKQDLLLLENQLPFPVLKSLMSLTPDGKDHGMKIINDFLSL------------QILQQSNHQRRPVLTWLVKGYLLLLLIYTTVAYPFH-----DLQKVGIYFKPSKTNTLMDVEFVS-SIFYATLKLPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLINDAEDVKVLRSNGILINYLGPDQKVADLFNQIGHSREPNTNVYNDVKGEINLSCDSIWKKWIAECLQTYFSSPWAFIAFVAAATGLVLTATQTYYT 440          

Query:  190 PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIY-KYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKE---LKKSIDEFVGRNSPAAAPADQN---------GQNPEAEEQRSQPGQEVEA-EPTHLLELLRTTMLP--------------YESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGI-LHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            P+I KVP +LRQ +   K Y+P + ++GP+HH + P+    EK+K+   + FV DS     D   KV +   + R+CY E++T ++DDE    ++F+DGC  L+FI+      E+ ++   QV  V+ D+                       E     K I++F+ R+  A  P  ++         G+    + +++   +E E  +P HLL LL T  +               Y     ++L+  GI F+P+  N+   + F S   F G  L LP + +++S +   +NLIAYE C D   +  VTSY CFLDSLI   +DVK L+ + +L  F+  ++EVA LFN++  +LVPN   YS VK QIE    +   + +A++ H++FSSPW+ IA           ++Q+  ++
Sbjct:   44 PQIPKVPRLLRQIQSNQKCYDPSLVSIGPYHHGK-PELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEKFTQIMFLDGCFILQFIFFLLRRPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGEGGGRNKLINDFI-RHIRALPPRKESIKEMIKKFAGKCIWKQPKKTWGNKETEDHQPVHLLGLLHTDHINKEACSHCSTRSSDWYSYRSAKDLRTVGIRFRPNWTNAYSDVEFKSS--FRGSRLILPPVTIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVLNIFV-REQEVADLFNQMSRNLVPNPYAYSDVKRQIELDRKSIIKKWVAEWLHDYFSSPWSFIALVAATFTIVLTVIQSYVAI 456          

Query:  190 PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHA-RLPQYEYAEKIKLKLAANFVRDSKQNDADLL-KKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEE----QRSQPGQEVEAEPTHLLE-LLRTTMLPYESEKK---------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPN-NDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHSS 1374
            P I KVP  L+ + K  + Y+P V ++GP+H+  R  +    EK+K+++A  FV DSK  D ++L  +V       ++ Y+  +   +DDE    M+F+DGC  L+FI    +     +   Q+  V+ D+                    +  +L  S+ + +          D  G+     +    Q  Q  Q  +  P  +L  L++  + P     K         ++LQ  GIHFKPS+ ++L  + F S  +F+  L +P I ++ +TR   +NL+AYE    F +D  VTSYICF+DSLID  +DVK LR K IL N+LG D++VA LFN+IG  L PN N +Y+ VK +I    D+   + +A++   +FSSPW  IAF            QT Y+V  Y SS
Sbjct:   70 PMIPKVPDKLKHENK--ECYKPSVVSIGPYHYKDRQNKLHEVEKLKVQMAREFVLDSKIKDIEILYSEVAKVAENAKRFYEGSSISCFDDEQFTRMMFLDGCFILQFIRGVMD-NKLDMSDQQIILVKQDLLL------------------LENQLPFSVLKSL---MSLKNDGDDRGKEININDFLLLQILQ--QSDQRRPVWVLSWLVKGNLFPKSKLGKRGHNLYYSAKDLQKVGIHFKPSKTSTLMDVKFVS-SIFYATLKIPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLIDDAEDVKVLRSKGILTNYLGPDQKVADLFNQIGRSLEPNTNIVYNDVKRKINVSCDSTWKKWIAEWLQTYFSSPWAFIAFVAAAAVLVLTATQTYYTVYPYKSS 453          

Query:  190 PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIY-KYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKEL---KKSIDEFVGRNSPAAAPADQN---------GQNPEAEEQRSQPGQEVEA-EPTHLLELLRTTMLP--------------YESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            P+I KVP +LRQ +   K Y+P + ++GP+HH + P+    EK+K+   + FV DS     D   KV +   + R+CY E++T ++DDE    ++F+DGC  L+FI+      E+ ++   QV  V+ D+                       E     K I++F+ R+  A  P  ++         G+    + Q++   +E E  +P HLL LL T  +               Y     ++L+  GI F+P+  N+   + F S  +    L LP I +++S +   +NLIAYE C D   +  VTSY CFLDSLI   +DVK L+ + +L  F+  ++EVA LFN++  +LVPN   YS VK +IE    +   + +A++ H +FSSPW+ IA            +Q+ +++
Sbjct:    4 PQIPKVPRLLRQIQSNQKCYDPSLVSIGPYHHGK-PELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEKFTQIMFLDGCFILQFIFFLLRRPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGEEGGGNKLINDFI-RHIRALPPQQESFKEMIKKFAGKCIWKQPQKTWGNKETEEHQPVHLLGLLHTDHINKEACSHCSTRSCDWYSYRSSKDLRKVGIRFRPNWTNAYSDVEFKS-SVRGSRLILPPITIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVLNIFV-REQEVADLFNQMSRNLVPNPYAYSDVKRRIELDRKSIIKKWVAEWMHTYFSSPWSFIALVAATFTIVLTGIQSYFAI 416          

Query:  157 EAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDD--EFLAWMLFVDGCSTLEFIY-KYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXX-IHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVE---AEPT--------HLLELLRTTMLP------------YESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            E     +++  P+I +VP +        K YEP V ++GP++H +L + +  EK K  +   FV+ SK+   D+ + V D   + R+ Y E+ + K DD  EF   M+F+DGC  ++F+Y    + EN ++     A V  D+                       +E  K I +F+          +   +      +++ P + +     +P         HLLEL     +             Y      EL+  GIHFKPS+      + F    L  G L +P + +D+ST+   +NL+AYE C   +    VTSYICF+DSLID P+DV+ LR + IL   LG++EEVA+LFNE+   LVPN   ++ VK+ IE H+ N   R +A+    +FSSPW+ I             +Q+ +++
Sbjct:    4 ERTEAMSQQQGPRIPRVPQIFSGIGSNKKCYEPKVVSIGPYYHGKLDRLQEMEKSKCNMVRGFVQQSKKLIEDVYQTVVDVAEDARRYYVEDESVKLDDMTEFTR-MMFLDGCFVIQFMYCLLRDHENLKMSSHAAALVTRDLLLLENQLPFLVLRSLMKLRFGSDEEGMKLIKDFIKHIRAMPRQRESCWKKISKFFRKTIPRRALNYSAKDPAMGEYYGAGHLLELFHMHFVDKNFSVDSSKTSLYRYHPAMELRTVGIHFKPSKARQFTDVQFKPTWLA-GRLKIPPLTIDESTKSMLLNLVAYEACLGDNKKLWVTSYICFMDSLIDHPEDVRVLRSQGILLVTLGSEEEVARLFNEVAKYLVPNPHAFNKVKNDIESHFRNTIKRWVAEHVDTYFSSPWSFITLVAASLTIALTAIQSYFTL 428          

Query:   79 PAEIEVSITIHEEASPREERLNKLREEAPPIQAEKVK------PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDEL-ENFQIKRDQVAFVEHDIF---------XXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNP-----------EAEEQRSQPGQEVEA---EPTHLLELLRTTMLP---------------YESEKKE----------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDN 1233
            P +I++ I  H        R ++  +     + E+        P I +VP   R+ +     Y+P V ++GP+HH + P+ +  E  K+  A+ FV +S+     +  KVE   +  RKCY E++T+K++D+  + M+F+DGC  L F +   E  E  ++    V+ V  D+F                            + +   K I     R         +N                + +    P  E+ A   +P HLLEL     +                Y+ + ++          +L+ +GIHFKPS+ +    + F +  L  G L++P +++DDST+P  +NL+AYE C    +D+ VTSY+CF+DSLID   DVK LR K IL + LG+D++VA+LFNEI   LVPN   YS VK  IE+HY N
Sbjct:    2 PEKIDIVIADHASLQQSTSRFDEWLKSMMDRKREQTGNYQLGGPIIPRVPPTFRKIENNSGCYDPSVVSIGPYHHGK-PELKEMEDNKVTFASQFVMESQVAPDTMFCKVEGVASNARKCYTEDSTQKFEDKEFSQMMFLDGCFILHFFFCLSEQPEKLKMSNHHVSLVARDLFLLENQLPFEVLLELMSLRFNIQGGERVDLFEPFFKHIRSMPPRRESCREKLSKNLATISSFFRSLLKLFSSTDHPKSPTNELTAIHRKPAHLLELFHNKFVARSIIDAAGVKDHKSWYKDDSRKSWSGRYYPAKDLRKAGIHFKPSKTSLFTDVSF-TPTLLAGRLYIPPLRIDDSTKPLLLNLVAYEACLGTCDDW-VTSYVCFMDSLIDHHKDVKELRSKGILISTLGSDKQVAELFNEISDYLVPNPYAYSKVKRDIENHYRN 438          

Query:  157 EAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDS-KQNDADLLKKVEDNINELRKCYDEEATKKYDD--EFLAWMLFVDGCSTLEFIY-KYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKE----------------------LKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELL-----------------RTTMLPYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDN 1233
            E     +++  P+I +VP +    +   K YEP+V ++GP++H +L  +   EK K  +   FV+ S K N  +L K VED     R+CYDE+ +   +D  EF   M+F+DGC  ++F++    + +N ++     A V  D+F                      E                       +K I +F  +  P  A ++ + ++PE  E             +HLLEL                  RT++  Y      +L+  GIHFKPS+ +    + F    L  G L +P + +DDST+P  +NL+AYE C   ++   VTSYICF+DSLIDQP+DV+ LR + +L   LG++EEVA+LFNE+   LVPN   ++ VK  IE H  N
Sbjct:    4 ERTETMSQQQGPRIPRVPQIFSGIESNKKCYEPMVVSIGPYYHGKLDGFLEMEKCKCNMVRGFVQQSGKHNIEELYKTVEDVAEVARRCYDEDGSVILNDMTEFTK-MMFLDGCFVIQFMHCLLRDHQNLKMSSHFAALVARDMFLLENQLPFVVLRSLMKLRFGSDEEGIKLIKDFIKHIRAMPRQRVSCRKKISKFFSKTIPRIAISNYSAKDPEMGEYYGA---------SHLLELFHMHFVTSVDKNVTVDSSRTSLYRYHPAM--DLRRVGIHFKPSKTSQFTDVQFKPTWLA-GRLQIPALTIDDSTKPLLLNLVAYEACLGDNDKLWVTSYICFMDSLIDQPEDVRVLRSQGVLIVTLGSEEEVARLFNEVANYLVPNPLAFNKVKKDIESHCRN 392          

Query:    1 MAQKDENV---------RQVTKXXXXXXXXXXXXXPAEI-------EVSITIHEEA--SPREERLNKLREE-APPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQ--NDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAP---ADQNGQNPEAEEQRS----QPGQEVEAEPTH-LLELLRTTMLPYES------EKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            M+QKDENV          +V K             PAEI       E  ITIHEE   + R E+L K+R   A   Q +   PKIQ+VPFMLR  K  DKYYEP V ALGP HH +  +Y+ AEK+KL+L  +F++DS+Q  ND  LLK VED I ELR+CYD EATK +DDE LAWMLFVDGCSTLEF+ KY ELE F+IKRDQVAFVE D+FX                  +  +L   + E +  +S    P   + + G      + R     +P Q  +   TH LL+LL+T + P  S         +ELQA+GIHF+PSE NSL  IYF    L  G L+LP IKVDDS  PKFMN+IAYEMCPDF NDF VTSYI FLDSLID  DDVKHLRKK I++N LG+D+EVA+LFNEI TDLVPN  IY  V  QIE HY       MAQFFH+HF+SPWT + F           +QT Y+
Sbjct:    1 MSQKDENVVSMKKELSXTKVAKRGGGQASGGDQGQPAEITTTEQTSEEXITIHEEVIRTSRGEKLKKMRXALAEAAQKQNAXPKIQRVPFMLRDHKNLDKYYEPRVVALGPRHHGK-EKYKQAEKVKLQLTEHFIKDSEQTNNDETLLKNVEDKIKELRECYDXEATKDHDDEALAWMLFVDGCSTLEFMXKYXELEXFKIKRDQVAFVEQDMFX------------------LENQLPYQLXELLISSSNKRRPPSLSTEPGCTHHILDLRPMVGPRPSQSTKPGCTHRLLDLLQTMVXPRPSXLXHSFRNVQELQAAGIHFRPSEKNSLMDIYFKPLFLCCGFLYLPIIKVDDSMGPKFMNIIAYEMCPDFQNDFVVTSYIGFLDSLIDHADDVKHLRKKGIVQNLLGSDQEVAELFNEISTDLVPNXAIYRXVTAQIEXHYKTKWKTWMAQFFHDHFNSPWTFLGFIGVLLGLGLSGMQTWYA 467          

Query:  121 SPREERLNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKY--DELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML--PYESEKK------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            S +EER  KLR+ AP        PKIQKVPFMLR+ K  +KYYEP   A+GPFHH   P+ E AE+ KL L   F++ + Q    L +KVE  I ELR+CY EEAT+ YDDE LAWMLF+DGCSTL+FI+ +  +ELE   IKRDQ+AF + D+F                     ++LKK+I+ +V  N  A        +     E+  +P  + E EP HLL+LLRT ML  P   +K+            +EL A+GIHFK S  + L  I F S H F G L LP I VDDST PKFMNLIAYEMCPDF NDF VTSYI FLD+LID  DDVK LR   +L N LG+D+EVA+LFNEIGTDLVPN DIY  VK +IE HY       M+QF H+HF SPWT +AF           +QT ++V
Sbjct:    7 SSKEERFEKLRK-APEAPDYSSNPKIQKVPFMLRKPKTSEKYYEPRAVAIGPFHHGN-PRCELAEEFKLMLTKRFLKYTSQTVEALHQKVEKKIKELRECYAEEATQTYDDETLAWMLFLDGCSTLQFIHSFVDEELEELSIKRDQIAFAQQDLFLLENQVPYQVLELLMSSSNKCEDLKKAIETYVQANIGAPGKKQSEKKVAITMEKEKEPAHQ-EKEPAHLLDLLRTRMLGPPKNPDKRAKDHSVQSFRNVQELDAAGIHFKLSNSSLLGDISFVS-HSFAGYLSLPAISVDDSTGPKFMNLIAYEMCPDFQNDFAVTSYISFLDALIDHADDVKELRSAGVLYNLLGSDKEVAKLFNEIGTDLVPNTDIYHDVKAEIEKHYKTKWKTWMSQFCHDHFRSPWTFLAFVGVLAALGLTGIQTWFAV 430          

Query:    1 MAQKDENV---------RQVTKXXXXXXXXXXXXXPAEI-------EVSITIHEEASPREERLNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML---PYESEKK--------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            M++KDENV          +VTK             PAEI       EV ITIHEEA  R  R  KL                          KKF K+ + + + +        P      K     ++  + +++     LLKKV D IN+LR+CYDE+ATK YDDE LAWMLFVDGCSTLEF+YKY++LE F+IKRDQVAF E D+                    IH+EL  SI+ F+  +    AP D                   + EPTHLL+LLRT M+   P  S K               +ELQA+GIHF+ S+ NSLR+I F       G L+LP IKVDDS RPKFMN+IAYEMC DF NDF VTSYI FLDSLID PDDVKHLRKK I+RN LG+DEEVAQLFNEI TDLVPN+ IY +VK QIEDHY       MAQFFH+HF+SPWT +AF           +QT Y+V
Sbjct:    1 MSEKDENVVCMKKELSVTKVTKSGGGQASGGDQGQPAEITTTEQTSEVVITIHEEAI-RTRRGEKL--------------------------KKFGKWQKQLKSKMPNQRSKGFPSCSAITKFSTSASSQGLLNAET----LLKKVGDKINDLRECYDEKATKDYDDEALAWMLFVDGCSTLEFMYKYEKLEEFKIKRDQVAFAEQDMLLLENQLPHRLLKWLIKKSKIHQELNTSIEGFIRMHG--GAPRDP----------------ATKREPTHLLDLLRTRMVGCPPSPSTKSGRRSTEGGHSFRNVQELQAAGIHFRYSKTNSLRAISFKLRFQCCGFLYLPIIKVDDSMRPKFMNMIAYEMCSDFQNDFEVTSYIGFLDSLIDHPDDVKHLRKKGIVRNLLGSDEEVAQLFNEIATDLVPNDAIYRNVKTQIEDHYKTKWKTWMAQFFHDHFNSPWTFLAFIGVLLGLGLSGIQTWYAV 436          

Query:  118 ASPREERLNKLRE-------EAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDE--FLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPA-------DQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML--------------PYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHSSK 1377
            A   E+R N+LR+        +  +   + +P IQ V   LR +K  +KY+EP V A+GP HH + P++E   ++K +LAA+FV DS +++  L K+VEDNI EL++CYDE+ T++YD +   LAWM FVDGCS L+FI KY  LE F+IKRDQV F E D+F                    +++L   I  F+  +S AA  +        +  +     E R     E     THLLELLRT ML              P      +EL A+GIHF+ SEG  LR I F S   F G L LP +  D    P F+NLIAYEMCPDF ND+ VTSY+ FL S I  P+D K LR  +IL N L  DE +AQLFNEIG DLV N  I   +  ++E HY +     MAQFF +HFSSPW  +AF           +QT YS++ YH  K
Sbjct:    2 ADSLEQRFNRLRDAGTKNQDSSTSVVPSRSRPIIQNVSRTLRSNKNLEKYFEPRVLAIGPIHHGKFPEWE---ELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQKYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLWHGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGPAKNGREAADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSL-CFAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSII-HISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSIISYHYPK 444          

Query:  775 PTHLLELLRTTMLPYESEKKEELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIA 1299
            P  +LE+L ++     S+K+EEL+           +S++   + +     G L LP I VDDST PKFMNLI YEMCP FH DFGVTSYI FL +LID   DVK LR   +L N LG+D++V ++FNE+  DLVPN  IY      IE+HY+      +++FF+ HFSSPWT +A
Sbjct:  113 PYKILEMLMSS-----SDKREELK-----------DSIKIYVWANI----GFLCLPPISVDDSTGPKFMNLITYEMCPGFHTDFGVTSYIKFLRALIDHASDVKKLRSVSVLYNLLGSDKKVVEIFNELRIDLVPNTRIYCDAIADIENHYETKWKTCISRFFNHHFSSPWTFLA 267          

Query:  268 LGPFHHARLPQYEYAEKIKLKLAANFVR-DSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKY--DELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRN 684
            + PFHH   P+ E AE+ K  +   F+   S+Q   D+  K+++ + ELR CY EEATK+YD+E LAWMLF+DGCS L+F++ +   +LE   I+ DQ+AFV H++F                     +ELK SI  +V  N
Sbjct:    1 MDPFHHGN-PRCELAEEFKHMMTKIFLEYTSRQTAEDVHHKIDEKVKELRDCYAEEATKRYDEETLAWMLFIDGCSILQFMHSFVHKKLEELSIRMDQIAFVRHNLFLLENQVPYKILEMLMSSSDKREELKDSIKIYVWAN 141          

Query:  241 KYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDA---DLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQ--------VAFVEHDIFXXXXXXXXXXXXXXXXXXXI--HKELKKSID----EFVGRNSPAAAPADQNGQNPEAEEQR----SQPGQEVEAEPTHLLELLRTTMLPYESEKKE--------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNND--IYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYH 1368
            K Y P + ++GP+H    P+ +  E+ K K   + +  ++       D LK +E    + R+CY E       +EFL  ML +DGC  +E + K   L  F+  RD         + F+  D                        HKE  KS+     EF   +        Q   N   +       S+   E+     HLL+LLR++++P   E+                +L  +GI   P +G S   I F       G++ +P I +DD   P  +N +AYE C    +   +T+Y   LD L++   DV++L  + IL N+ GND EVAQ  N +G D+  + D    S + + +  +Y N  +   A F + +F++PW+ I+           +VQT+Y+V+ Y+
Sbjct:   66 KSYNPHIVSIGPYHRGE-PRVKMIEEHKWKYLGSLLARTEPKGLSLKDYLKALEPLEQQARECYSERINLT-TEEFLE-MLVLDGCFIIELLRKVGLLVRFE--RDDPLVXMVWIIPFLVRDFLRLENQIPYFVLLALFDLTTTEEHKENGKSLSLLALEFFNNHMQRPDHVIQKHHNLTGKLSNFNDISKTFFEISLFCMHLLDLLRSSVIPPGHEEPRSSNTIPTHTIHCVSKLXRAGIKLNPGKGESFLVIKFK-----RGVIEMPTITIDDFMSPFLLNCVAYEQCHKSSSKH-ITTYATLLDCLVNTYKDVEYLCDRNILENYFGNDGEVAQFINNLGKDVAFDMDRCYLSKLFNDVHHYYGNSWHVQWASFKYTYFNTPWSFISAFVALILLILTLVQTIYTVMSYY 467          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFI---------YKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPT------HLLELLRTTMLPYE------------------SEKKE--------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCP-DFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPN-NDIY-SSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYH 1368
            I KVP  LR+    DK   P + +LGP+HH +  +    ++ K +     ++ + Q     L  +++   + R CY+  A           M+ +DGC  LE             Y   +     R  +  ++ D+                       E K  + +   R      P D+     +  +  S        +P       H L++ R ++L                     ++K+         EL+ +GI FK  + +    + F +     GIL +P++ + D T+  F+NLIA+E C  D  ND  +TSY+ F+D+LI+ P DV +L    I+ ++LG+D+EVA LFN +  ++V + ND Y S +   +  +YD+  N   A   H +FS+PW  ++F            QT Y V GY+
Sbjct:  104 IYKVPHYLREGD--DKAIVPQIVSLGPYHHGKR-RLRQMDRHKWRSLLRMLKRTNQCIELYLNSIKEVEEKARACYEGPAAMGLSSNEFVEMMVLDGCFVLELFRGVGEGFKQLGYPRNDPIFAMRGSMHSIQRDMIMLENQLPLFILDRLLGLQLGDPEQKGLVAKLALRFFDPLMPTDEPLTKSDRNKLESSLAYATTFDPLSEQGGLHCLDVFRRSLLRTGLQAVPRVWIKRWSHSNRVADKRRQQLIHCVTELKEAGIKFKKRKTDRFWDVKFEN-----GILKIPRLLIHDGTKSLFLNLIAFEQCHLDCSND--ITSYVIFMDNLINSPQDVGYLHYCGIIEHWLGSDDEVADLFNRLCQEVVFDINDSYLSPLSADVNRYYDHRWNAWRASLKHNYFSNPWAILSFIAAVVLLFLTFAQTFYGVYGYY 528          

Query:  109 HEEASPREERLNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDE--FVGRNSPAAAPADQNGQ------NPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKE--------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNND--IYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            H+  +PR +    + +E   +        I KVP  LR     +K Y P V ++GP HH +    E  E+ K +    F+  +  +  D + K++    +LR CY     +   DEF+  ++ VD    +E + +Y              ++ HD                     +  +L   I E  F     PA  P+  +        +     +R   G     +  H ++L+RT  LP + E+ E              +L  +G+ FK     +L  + F       GIL +P + + DST     NL+A+E C    N      YI  +D L++ P+DV+ L K  I+ N LG++ EV+ L N +G  ++   D   Y+++   +  +Y+   N+  A   H++F++PW  I+           ++QTV S+
Sbjct:    9 HDFENPRIQLTTSMSQELDGLTPLSASCCIYKVPEQLRCVN--EKAYTPQVVSIGPIHHGK-KGLEDMEEHKKRYLQYFLYRTGVSLEDYVTKIKGKEEKLRSCY-AHTIELCSDEFVR-IILVDAAFIIELLLRYG------------GYIVHDSNDRIFNKPWLINIICPDMLLLENQLPFFIXEDLFATAEVPATVPSVFDLSYTYCKVSTSLYVKRDGLGSSSSFKVEHFVDLVRTLNLPTDQEENENRGSVESLAVPSMTKLHQAGVKFKARSSKNLFDMCFQE-----GILEIPNLNISDSTELVLRNLVAFEQCHCTPNTRYFNDYIFLMDYLVNTPNDVELLVKNGIVENMLGDNNEVSTLINSLGKGVLVFRDEFYYATLMKDLNKYYEKPWNKWKADLKHKYFNTPWKIISVIAATFIIILTLIQTVSSI 426          

Query:  241 KYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDA---DLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQ--------VAFVEHDIFXXXXXXXXXXXXXXXXXXXI--HKELKKSID----EFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPT---------------HLLELLRTTMLPYESEKKE--------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNND--IYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYH 1368
            K Y P + ++GP+H    P+ +  E+ K K   + +  ++       D LK +E    + R+CY E       DEFL  ML +DGC  +E   K+  L  F+  RD         + F+  D       X X           +  HKE  KS+     EF   +        Q  +N      ++     V                    HLL+LLR++++P   E+                +L+ +GI F P +  S   I F       G++ +P I +DD      +N +AYE C    +   +T+Y   LD L++   DV++L  + I+ N  GND EVA+  N +G D+  + D    + + + + D+Y N  +   A F + +F +PW+ I+           ++QT Y+VL Y+
Sbjct:  105 KSYNPHIVSIGPYHRGE-PRLKMIEEHKWKYXGSLLARTEPKGLTLXDYLKALEPLEQKARECYSEXINLS-TDEFLE-MLVLDGCFIIELFRKFGLLVRFE--RDDPLVNMVWIIPFLXRDFLRLENQXPXFVLLTLFDLTTMEEHKENGKSLSLLAVEFFNNHMQRPDNVIQKHRNLTGMLSQTSIFSSVHEFSAPLYVNIVFNTLFXGMHLLDLLRSSVIPPGHEEPRSSNTIPTHTIHCVSKLRRAGIKFNPGKDESFLVIKFK-----RGVIEMPPITIDDFMSSFLLNCVAYEQCHKSSSKH-ITTYATLLDCLVNTYKDVEYLSDRNIIENCFGNDGEVARFINNLGKDVAFDMDRCYLAKLFNDVHDYYGNSWHVQWASFKYTYFDTPWSFISAFAALILLILTLMQTFYTVLSYY 517          

Query:  196 IQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSI--DEFVGRNSPAAAPADQNGQNPEAEEQRS---------QPGQEVEAEPTHLLELLRTTMLPYESEKKE--------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNND--IYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            I +VP  LR+    +K Y P V ++GP HH +    E  E+ K +    F+  +  + A  ++K++D   ELR CY         DEF+  ++ VD    +E + +Y+             +V  D                     +  +L   I  D F     PA+ P+  +      +E  +         +P  +VE    H ++L+RT  LP   E  +              +L+ +G+ FK   G +L  I F       GIL +P++ + D+T     NLIA+E C    N F  + YI  +D+L++ P+DV+ L K  I+ + LG++ EV+ L N +G  L    D   Y+++  ++  +Y+   N+  A    ++F+SPWT I+           ++QTV S
Sbjct:   38 IYRVPEELRRVN--EKAYTPQVVSIGPLHHGK-EGLEDMEEHKKRYLKYFLDRTGVSLAGCVQKIKDKEAELRGCY-AHTIGLCSDEFVR-IILVDAVFIIELLLRYE------------GYVVRDSNDRIFNKPWLLKFIVPDMLLLENQLPLFILEDLFATAEVPASVPSVLDLFYEFCKESTNFYMEKGNWERPSFKVE----HFVDLVRTLHLPTPEENLKNGESVETLAVPSMTKLRQAGVKFKARSGKNLFDICFKD-----GILEIPKLYIYDNTELVLRNLIAFEQCHCTRNTFYFSDYIILMDNLVNTPNDVELLVKNGIVEHLLGDNNEVSTLINSLGKGLFVFRDEFYYATLLKELNIYYEKPWNKWKADLKQKYFNSPWTTISVIAATFIIILTLIQTVCS 424          

Query:   94 VSITIHEEASP-REERLNKLR---EEAPPIQAEKVK-PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYD---ELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKK---------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHS 1371
            + I + + AS  RE+R   +    E++   Q  + K  +I KVP MLR  K F   +EP V ++GP+HH +      AE +K  +   F+ +S+Q    L  K+   I+ELR CY++ ATKKY+DE LAWM+ VDGCS L FI  Y    +L++  IK    AF + D+F                     +E  + I++F+G  +    PA ++                 E +P HLL+LLR  +L  ++  +                EL+A+GI FKP++  SLR I F S+ L  G L LP+I +DDST+ +F+NLIAYEMCP+  N+  VTSYICFLDSLID P+DVK LR++ +LRNFLG+D+EVA+LFNEI TDLVP++D Y  VK +I+ HY+   +  +A+  H HFSSPWT +AF           +QT Y+V   H+
Sbjct:   47 IDIVVEDNASSSREKRFKSVMGGPEDSKRSQLSETKWARIPKVPHMLRGTKDFKILFEPRVVSVGPYHHHK-HDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDEDLAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGF--EEGMQMIEQFIGSAAETDPPAVKSDN---------------EEKPAHLLDLLRRRLLGNQTASETEAGKGTGWNSFRNVNELKAAGIRFKPAKSGSLRDISFNSYILL-GFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTVFPRHN 476          

Query:   79 PAEIEVSITIHEEASPREER-LNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKE--LKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML-------------PYESEKK---------------------------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLG 1362
            P E  + I    E SPR +  +  LR+     +++   P+  KVP MLR  + F K YEP V ++GP+HH + P     E IK   A  F+ DS Q+   L  K+  NI  +RKCYD  +T +YDDE LAWM+ +DGC  L+FI +  ++ NF ++  Q+ FV  D+F                    + +  +KK I EFV +              PEA ++      E++ EP HLL LLR+++L               + EKK                                 ++L+ASGIH KPS  + L  + F S   FHG L LP+I +DD T+ KF+N++AYEMCPD  +D+G+TSYIC LD LID  DDVK LR K IL N LGNDE+VAQLFNEIG DLV + + Y  VKD+I++HY+   N  +AQ  H+HFS+PWT IAF           VQT Y++ G
Sbjct:   29 PKEHRIDIN---EISPRVKNWIGGLRKTEERTESQTQWPRTPKVPQMLRGTQDFKKMYEPRVISIGPYHHGK-PDLGRVEMIKPPCAQEFLADSNQDIEALYTKIRSNIETVRKCYDWSSTSEYDDEALAWMMLLDGCFLLQFIRRKGKI-NF-LRNHQIIFVLQDLFLLENQLPYGVLKLIFEEAKFNDDSLMKKKIKEFVTKTG-----------RPEASDE------ELDEEPPHLLHLLRSSLLGRDKRIRGSQPEQEQQPEKKGKSSSSQGGDWGFRCPWKKCKQRAIWLYSFRSIKDLKASGIHLKPSRTSVLTDVSFKS-SFFHGYLKLPRIIIDDFTKKKFLNMVAYEMCPDAPDDYGITSYICLLDDLIDHADDVKELRSKNILYNLLGNDEDVAQLFNEIGNDLV-DPEAYEDVKDRIQEHYNKRMNTWIAQALHDHFSTPWTIIAFIAAVLILFLTGVQTYYALPG 480          

Query:  106 IHEEASPREERLNKLREEAPP-IQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKY----DELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKE--LKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML----------PYESEKK-----------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYS 1353
            I  E +P  E  N++ ++A   I ++   P++ KVP MLR  + F K YEP V ++GP+HH + P     E IK   A  F+    Q+  DL  K+E  I  +RKCYD + T +Y+DE L WM+ +DG   L+FI       D++ N  ++  Q+ FV  D+F                         ++K+I EFV   +    P   + +    EE +         EP+HLLELLR+ +L            E+EKK                 +EL+A+GI+ KPS  + L  I F S H F+G L LP+I +D  T+ KF+N++AYEMCPD   D  VTSY+CFL  LIDQ DDVK LR K IL N LG+DE+VA++FNEIG DLV +   Y  VK +I+ HYD   N  +A+  HEHF SPWT  +            +QT Y+
Sbjct:   34 IDVEINPTVENWNRIVQKAKERIPSQSQWPRLPKVPHMLRGTQDFKKLYEPRVISIGPYHHGK-PHLRPGEMIKPLYAEQFLAGINQDFKDLYTKIESKIEAVRKCYDTKPTNRYNDEALIWMMLLDGLFLLQFIGSTVDPRDDMSNV-LRDHQINFVTQDLFLLENQLPFGVLKLIFEGANFQDAPPMEKTIKEFV---TDFGMPEGLSSEIQLEEENK---------EPSHLLELLRSALLGGYKKIQPKQKQEAEKKGKSSSSGGGIWESFRHIKELKAAGIYLKPSRKSFLTEISFKS-HFFYGCLKLPRITIDGFTKTKFLNMVAYEMCPDAPVDQAVTSYVCFLYELIDQADDVKELRSKHILHNLLGSDEDVAKIFNEIGNDLV-DPGAYGDVKARIQKHYDKRVNTWIAEGLHEHFRSPWTFTSLIAAVWILIVTGLQTYYA 467          

Query:  187 KPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEE---------ATKKYDDEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEV---EAEPTHLLELLRTTMLPYESEKK-EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            +PKIQ+V   LR  K F+K+Y P   ++GP HH        AEK KL  AA ++ ++     DL KK+ DNI+EL+  +D++         A  +  +E L+WMLFVDGCS L  + K   +E  +  IK DQ+  V  D+                        L +S+  F+  +  A     Q+G+  +   +R   G  +   EA   +L +  R   +   + +  ++L+  GI+FK S+    R I F S  LF   L LP+I VDDS+   F+NLIAYEMCPDFHND+G+ S+  F+DSLID P+DVK LR K+IL N LG+DEEVA+LFN I TDLVPN D Y  V+ +I DHY N  N  +AQ F  +FSSPW  IAF           +QT ++V
Sbjct:   24 RPKIQRVLKSLRNRKNFEKHYSPKCVSIGPIHHHNT-NLILAEKYKLMWAAKYIENNGYIPEDLHKKIADNIDELKGHFDDDVLTSTRWSLAGFRSLEEKLSWMLFVDGCSLLYILEKANLNEPWHMNIKVDQLVLVMMDVLLLENQLPYQVLKLLWKDED-ESGLIESMMNFLDCHHWATPDESQSGKKKDMVPKRKGEGVTIRNNEANKENLSKKSRDEKVKMMTYRNIQDLRDVGINFKSSKTRRPRDIDF-SEGLFTAELTLPEIVVDDSSATTFLNLIAYEMCPDFHNDYGICSFAAFMDSLIDNPEDVKLLRSKEILLNSLGSDEEVAELFNIISTDLVPNADTYLEVRAKIHDHYRNRCNTWIAQGFRTYFSSPWAIIAFIAALIALVLTFIQTWFTV 425          

Query:  187 KPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEAT----KKYDD-----EFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQN-----------------------------GQNPEAEEQRSQPGQEVEAE-------------PTHLLELLR-------TTMLPYESEKK---------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            +PKIQ+V   LR  K F+K+Y P + ++GP HH   P  +  EK KL  AA ++ +  +N  DL KK+ DNINEL+  + ++      +  +D     E L+WMLFVDGCS L  + K          IK DQ+  V  D+                       EL KS+  F+  +  A     +N                              + P  +E+   P ++ E E             P HLL+L R       TT +  ES  +               ++L+A GI  K S+    R I F S  LF   L LP+I VDD++   F+NLIAYEMCPDF ND+G+ S+  F+DSLID P+DVK LR K IL N LG+DEEVA+LFN I TDLVPN++ Y  V+ +I DHY N  N  +A+ FH +FS+PW  IAF           +QT ++V
Sbjct:   26 RPKIQRVQEYLRNRKNFEKHYSPKLVSIGPIHHDN-PNLKTGEKYKLMWAAKYLENIGRNPRDLHKKIADNINELKGHFSDDVLTLTGQSLEDFGSLEEKLSWMLFVDGCSLLHILEKAKLHVPGQMNIKVDQLVLVMMDVLLLENQLPYEVLKLLWKDSD-ESELIKSMKNFLKCHHWATPDNKRNRRKRRNQETSNIVPDKTGKEQHSVLITNESETPSEKEKDMVPKRKGEGEHSLSIRNESQLETPFHLLDLQRNIILITSTTKINKESWSQKSSDEKVKMMTYRNIQDLRAVGIRLKSSKTRRPRDIDF-SEGLFAAELTLPEIVVDDTSAATFLNLIAYEMCPDFDNDYGICSFAAFMDSLIDNPEDVKLLRSKGILLNSLGSDEEVAELFNIISTDLVPNSETYFEVRAKIHDHYCNRCNTWIAEGFHTYFSNPWAIIAFIAAFTALVLTFIQTWFTV 487          

Query:  115 EASPREER-LNKLREEAPPIQAEKVKPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIYKYDELENFQIKR----DQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDE--FVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEA-EPTHLLELLRTTMLPYESEKKE---------------------------------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMA 1254
            E SPR +  +  L+      Q++   P+I KVP +LR    F++ YEP V ++GP+HH + P  +  E IKL+ A  F+ DS Q+   L  K+  NI  LRKCYD+  T   DDE LAWM+ +DGC  L+FI    +     +       Q+ FVE D+F                   +  +L   + +  F G      +  +Q  +N        QP  E+   E +HLL+LLR+ +L   + K+E                                       EL+A+GIH +PS    L  I F S+  F G L+LP I VDDST+ +F+N++AYEMCPD  ND+ VTSY+ FL  LID  DDVK LR + IL N LG+DE+VA++FNEI  D+V + ++Y  VK +I+  Y+   N  +A
Sbjct:   39 EISPRVKNWIKSLKNAEESTQSQSSWPRIPKVPQLLRGTHDFERLYEPRVISIGPYHHGK-PHLQPVETIKLQYAQKFLADSDQDIEALYTKIGSNIEALRKCYDKIPT---DDEKLAWMMLLDGCFLLQFIRSRKDGSTVDLSNVLRIHQINFVERDLFL------------------LENQLPFGVLQLIFEGAKFNDGSTMEQMIKNFVTRIASLQPSSEIRLDERSHLLDLLRSAILGKSAPKQERQPDKKGKSSSSSGGDGRFCCPWKKGKQQGIRQSFRNIKELKAAGIHLQPSRTRFLTDISFNSY-FFRGYLNLPPIIVDDSTKSRFLNIVAYEMCPDAPNDYTVTSYLRFLYELIDHADDVKELRSRHILINHLGSDEDVARIFNEIANDVV-DTEVYGDVKARIQKDYNKRVNTCIA 441          

Query:  187 KPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEAT----KKYD-----DEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNP--------EAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKK-----------------------------------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            +PKIQ+V   LR  K F+K+Y P + ++GP HH      +  EK KL  AA ++ ++     DL KK+ DNI+EL+  + ++      K  +     +E L+WMLFVDGCS L  + K   DE  +  IK DQ+  V  D+                       EL KS+  F+  +  A     Q  +          E E   S   +     PTHLL+L R  +L   + K                                    ++L+A GI  K S       + F S   F   L LP+I VDD++   F+NLIAYEMCPDF ND+G+ S+  F+DSLID+P+DVK LR K IL N LG+DEEVA  FN I TDLVPN  IY  V+++I +HY N     +A  FH +FS+PW  IAF           +QT ++V
Sbjct:   24 RPKIQRVAEYLRNRKNFEKHYSPKLLSVGPIHHDNT-NLKLGEKYKLMWAAKYIENTGHIPEDLHKKIADNIDELKGHFGDDVLTLTGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDND--SELIKSMMTFLDCHHWATPDESQPDKEKDMVPKGKGEGEHSVSITNESQLETPTHLLDLQRKIILTTSNSKTKSNEANNNKWSQKNSDENVKKNSKEDVKMMTYRSIQDLRAVGIRLKSSATRRPTDVDF-SAGWFAAKLTLPEIVVDDTSAATFLNLIAYEMCPDFENDYGICSFAAFMDSLIDRPEDVKELRSKGILLNSLGSDEEVADFFNIISTDLVPNTKIYFEVREKIHEHYCNKCKTWIALGFHTYFSNPWAIIAFLAAFIALALTFIQTWFAV 463          

Query:  172 QAEKVK-------PKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKY-DDEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXX------IHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQ------------------RSQPGQEVEAEPT-HLLELLRTTML-------------PYESEKKE-------------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSVLGYHS 1371
            Q EK K       PKIQ+V   LR  K F K+Y P + ++GP HH         EK KL   A ++  + Q+   L +K+  NI +L++ + E+    + DDE L+WML VDGCS L+ + K   D  E   +K DQ+  V  D+                          I KE  K       R +  A   D +    + E++                  + +   E+  EP  HLL+ LR T++                S+KK+                   EL+A+GI  K S    ++   F    L+   L LP+I VDD+T P F+NLIAYEMCPDF N++ + S++ F+DSLID PDDVK LRK  IL N LG+DEEVA LFN I  DLVPN + YS V+ QIE HY N     +A   H +FS+PW  IAF           +QT Y++   H+
Sbjct:   13 QLEKAKLIPQTSAPKIQRVAHYLRDRKHFAKHYSPRLVSIGPIHHGA-KNLLLGEKYKLMWTARYLERTNQDAQTLYQKIASNIKQLKELFAEDVIADFPDDEKLSWMLLVDGCSLLQILEKGKLDYPEEMNVKVDQLVLVWQDVLLLENQLPYQVLKLLTGPENEAMLLNIMKEFLKCHHLSPVRPNHRAKTQDMDKDITKQEDRAFTEEGCTSVCTKNESTLQGEHRVEIPQEPPIHLLDQLRRTVIHDPQKNHQDHRKKDTTSKKKKCKQNKKNEDSDIITYRNIKELRAAGISLKKSNSRRIKDTSFSCGWLY-AELKLPEITVDDTTAPSFLNLIAYEMCPDFTNNYEICSFVAFIDSLIDNPDDVKELRKAGILLNMLGSDEEVANLFNTISADLVPNMEGYSHVRPQIERHYRNKCKTWIALGSHTYFSNPWAIIAFHAAVLAIVLTFIQTWYAIHPAHA 477          

Query:  187 KPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQ--YEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEE----ATKKYD-----DEFLAWMLFVDGCSTLEFIYK--YDELENFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKEELQ---------------ASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            + +IQ+V   L+  K F+K+Y P + ++GP HH        +  EK KL  AA ++ ++  N  DL KK+ DNI+EL+  + ++    A K  +     +E L+WMLFVDGCS L  + K   DE  +  IK DQ+  V  D+                       EL KS+  F+ R+  A   +          E  +      E  PTHLL+L R  +L  +S+  + L+               A GI  K +   + +SI F     F   L LP+I VDD +    +NLIAYEMCPDF ND+G+ S+  F+DSLID P+DVK LR K IL N   +DEEVA LFN I T+ +P+ +IY  V+ +I++HY N     + Q  + +FS+PW  IAF          ++QT ++V
Sbjct:   25 RTQIQRVAEYLKNRKDFEKHYSPKLVSIGPIHHGNTSNANLKLGEKYKLTWAAKYIENAGLNPCDLHKKIIDNIDELKGHFSDDVLTLAGKSLEGFGSLEEKLSWMLFVDGCSLLYILEKAKLDEPGHMNIKVDQLVLVMMDVLLLENQLPYVVLKLLWKDNN-ESELIKSMKMFLTRHPWATLES--------ILELLTIISFSWEKLPTHLLDLQRNIILFTQSKSPKNLESHVRKMSYRSVQSLRAVGIRLKSTATRNPQSIEFAE-GWFTAKLTLPEIVVDDRSAATILNLIAYEMCPDFENDYGICSFATFMDSLIDHPEDVKLLRSKGILLNSPWSDEEVANLFNSIRTNFIPDTEIYFKVRAKIDEHYCNRWKTWIGQGLNTYFSNPWAFIAFVAAFIALALTLIQTWFTV 432          

Query:  187 KPKIQKVPFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDE-------EATKKYD--DEFLAWMLFVDGCSTLEFIYKYDELE--NFQIKRDQVAFVEHDIFXXXXXXXXXXXXXXXXXXXIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTML--------PYESEKK-----------EELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFXXXXXXXXXXIVQTVYSV 1356
            +PKIQ+VP  ++   KF ++Y P   ++GP HH      +  EK KL  AA +++++     DL KK+ DNI+EL+  + +       E+ + Y   +E L+WMLFVDGCS L  + K    E  +  +K DQ+  V  D+                       EL K +  F+  +  A     ++        +R Q  Q+    P HLL+L R  +L         Y++ K+           ++L+A GI  K S+    + I F     F   L LP+I VDD++   F+NLIAYEMCP+F ND+G+ S++ F+DSLID P+DVK LR K IL N LG+DEEVA+LFN IGTDLVPN + Y  VK ++ DHY  +   ++  ++     + +  IA            +QTV++V
Sbjct:   28 RPKIQRVPRYVKNRTKFKEHYSPKFVSIGPIHHGNT-DLKLGEKYKLMWAAKYIKNTGSIQKDLYKKIADNIDELKGHFSDDVLTLTGESLEGYHSLEEKLSWMLFVDGCSLLHILEKTMLYEPGHMNVKVDQLVLVMMDVLLLENQLPYQVLKLLWKDSN-ESELIKIMTNFLDCHHWATLDNKRS--------RRWQLNQDTTTIPAHLLDLQRNIILIKSTPKIENYKANKENWRMKTIYMNIKDLKALGIRLKSSKTRRPKDIDFTE-GWFTAELTLPEIVVDDTSATTFLNLIAYEMCPNFDNDYGICSFVAFMDSLIDHPEDVKVLRSKGILLNSLGSDEEVAELFNIIGTDLVPNPETYFEVKAKMIDHYYKYRTGIVRGYYTYFRIAAFIAIAL---------TFIQTVFTV 427